Caenorhabditis elegans

63 known processes

atg-18 (CELE_F41E6.13)

Protein ATG-18

atg-18 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
locomotionGO:004001116340.567
post embryonic developmentGO:000979121520.539
autophagyGO:0006914290.493
protein modification processGO:00362112070.491
organic substance catabolic processGO:19015752940.443
vulval developmentGO:00400253330.422
growthGO:00400075620.418
post embryonic organ developmentGO:00485693360.392
apoptotic processGO:00069154780.392
genitalia developmentGO:00488067410.387
cellular response to nutrient levelsGO:0031669130.377
Fly
single organism transportGO:00447654470.362
response to external stimulusGO:00096052890.346
Fly
protein metabolic processGO:00195384220.342
sex differentiationGO:00075489090.306
agingGO:00075688120.304
regulation of vulval developmentGO:00400282480.295
regulation of cellular component organizationGO:00511282480.292
endocytosisGO:00068978190.290
organelle fissionGO:00482853630.272
deathGO:00162655470.270
multicellular organismal reproductive processGO:00486098150.263
cellular protein modification processGO:00064642070.253
transportGO:000681010930.251
organ developmentGO:004851311020.250
programmed cell deathGO:00125015000.246
hermaphrodite genitalia developmentGO:00400357340.234
cell migrationGO:00164773060.230
organelle organizationGO:00069967830.220
Fly
positive regulation of macromolecule metabolic processGO:00106041490.210
cell cycle processGO:00224024820.204
cell cycleGO:00070495260.203
mitotic nuclear divisionGO:0007067890.202
regulation of developmental processGO:00507936840.197
gamete generationGO:00072764610.194
positive regulation of cellular processGO:00485223320.192
receptor mediated endocytosisGO:00068987150.191
multicellular organism reproductionGO:00325048190.185
development of primary sexual characteristicsGO:00451378400.184
single organism localizationGO:19025785180.181
sensory organ morphogenesisGO:009059620.174
negative regulation of vulval developmentGO:00400272060.170
small molecule metabolic processGO:00442811860.166
negative regulation of post embryonic developmentGO:00485812080.163
reproductive structure developmentGO:00486088500.160
negative regulation of nematode larval developmentGO:00610642080.160
gonad developmentGO:00084068400.157
establishment of localizationGO:005123411710.156
cellular catabolic processGO:00442481990.152
cellular protein metabolic processGO:00442672790.151
multi organism reproductive processGO:00447038670.151
cell developmentGO:00484686960.150
Fly
regulation of multicellular organismal processGO:00512397260.150
macromolecule modificationGO:00434122180.149
cell deathGO:00082195470.149
reproductive system developmentGO:00614588500.147
response to extracellular stimulusGO:0009991380.147
Fly
signalingGO:00230524010.143
Fly
macroautophagyGO:0016236110.143
Fly
neurogenesisGO:00220082360.141
negative regulation of multicellular organismal processGO:00512412360.133
macromolecular complex subunit organizationGO:00439333200.132
cellular response to chemical stimulusGO:00708871290.128
single organism reproductive processGO:004470211960.127
regulation of nematode larval developmentGO:00610622600.125
multicellular organismal agingGO:00102598120.124
developmental process involved in reproductionGO:000300611650.124
catabolic processGO:00090563180.123
proteolysisGO:0006508610.119
female gamete generationGO:00072922540.117
cytoskeleton organizationGO:00070103390.116
neuron differentiationGO:00301822170.115
neuron developmentGO:00486661990.111
regulation of biological qualityGO:00650087410.109
organic substance biosynthetic processGO:19015763230.108
neuron projection developmentGO:00311751870.105
nervous system developmentGO:00073992530.104
cell projection organizationGO:00300302310.103
regulation of post embryonic developmentGO:00485802600.102
anatomical structure formation involved in morphogenesisGO:00486462500.101
vesicle mediated transportGO:00161928520.101
regulation of primary metabolic processGO:00800902920.101
immune responseGO:00069551920.101
positive regulation of signalingGO:0023056660.101
regulation of signal transductionGO:00099661350.099
Fly
generation of neuronsGO:00486992350.099
cellular component movementGO:00069283880.098
negative regulation of developmental processGO:00510932270.097
actin filament based processGO:00300291910.097
ovipositionGO:00189913640.096
determination of adult lifespanGO:00083408120.095
chromosome organizationGO:00512761040.094
positive regulation of signal transductionGO:0009967400.094
germ cell developmentGO:00072813510.093
cell fate commitmentGO:00451651390.093
cellular process involved in reproduction in multicellular organismGO:00224123510.093
mitotic cell cycle processGO:19030471940.091
positive regulation of cellular metabolic processGO:00313251780.090
chromosome segregationGO:00070591800.090
positive regulation of metabolic processGO:00098931870.089
cell motilityGO:00488703130.088
meiotic cell cycle processGO:19030461700.088
intracellular signal transductionGO:0035556960.087
Fly
positive regulation of nitrogen compound metabolic processGO:00511731340.086
negative regulation of cellular component organizationGO:0051129330.086
multicellular organismal reproductive behaviorGO:00330573840.085
cellular biosynthetic processGO:00442493150.084
macromolecule catabolic processGO:00090572020.084
ubiquitin dependent protein catabolic processGO:0006511320.084
regulation of response to stimulusGO:00485832430.084
Fly
embryo developmentGO:000979030520.083
meiotic nuclear divisionGO:00071263000.083
single organism organelle organizationGO:19025895010.082
head developmentGO:006032210.081
multi multicellular organism processGO:00447063900.081
regulation of nuclear divisionGO:00517831150.080
body morphogenesisGO:00101716200.079
defense response to other organismGO:00985421000.078
Fly
regulation of multicellular organismal developmentGO:20000263170.077
cellular protein catabolic processGO:0044257370.076
cellular response to stressGO:00335541620.076
Fly
cellular component assembly involved in morphogenesisGO:00109271830.076
regulation of metabolic processGO:00192224780.076
cellular component biogenesisGO:00440852970.075
Fly
regulation of mitotic cell cycleGO:0007346760.075
spindle organizationGO:0007051920.075
single organism catabolic processGO:00447121290.074
Fly
defense responseGO:00069522960.073
Fly
molting cycleGO:00423032810.073
macromolecule localizationGO:00330367710.073
localization of cellGO:00516743130.073
single organism signalingGO:00447004010.071
Fly
embryo development ending in birth or egg hatchingGO:000979229920.070
oogenesisGO:00484772290.070
secretion by cellGO:00329401380.068
sexual reproductionGO:00199535460.068
biosynthetic processGO:00090583230.067
lipid storageGO:00199155650.067
regulation of apoptotic processGO:0042981360.067
cellular component assemblyGO:00226072930.066
Fly
regulation of cell cycle processGO:00105641450.066
regulation of growthGO:00400084090.065
tissue developmentGO:00098881120.065
Fly
positive regulation of developmental processGO:00510944080.064
meiotic cell cycleGO:00513213350.064
multi organism behaviorGO:00517053890.064
digestive tract morphogenesisGO:0048546760.064
cellular response to extracellular stimulusGO:0031668160.064
Fly
positive regulation of multicellular organismal processGO:00512404170.062
reproductive behaviorGO:00190983870.061
positive regulation of biosynthetic processGO:00098911090.061
regulation of cellular protein metabolic processGO:0032268750.059
regulation of organelle organizationGO:00330431640.059
response to abiotic stimulusGO:00096281520.059
protein catabolic processGO:00301631620.058
negative regulation of signalingGO:0023057610.058
Fly
maintenance of locationGO:00512355800.058
multicellular organism growthGO:00352643850.057
canonical wnt signaling pathwayGO:006007030.057
macromolecule biosynthetic processGO:00090592500.055
molting cycle collagen and cuticulin based cuticleGO:00189962810.054
regulation of cell divisionGO:00513021420.054
positive regulation of developmental growthGO:00486393540.053
cellular macromolecule biosynthetic processGO:00346452470.053
regulation of signalingGO:00230511720.052
Fly
secretionGO:00469031470.052
positive regulation of cell communicationGO:0010647690.052
cellular macromolecular complex assemblyGO:00346221840.052
regulation of multicellular organism growthGO:00400143730.050
regulation of locomotionGO:00400121610.050
cellular localizationGO:00516413600.050
cellular response to external stimulusGO:0071496160.049
Fly
organelle assemblyGO:00709252140.048
Fly
negative regulation of biological processGO:00485195670.048
Fly
negative regulation of macromolecule metabolic processGO:00106052290.048
response to biotic stimulusGO:00096071010.048
Fly
response to woundingGO:000961140.047
regulation of programmed cell deathGO:0043067500.047
positive regulation of nucleic acid templated transcriptionGO:19035081020.047
cellular response to starvationGO:0009267130.046
Fly
lipid localizationGO:00108765730.045
oxoacid metabolic processGO:0043436470.044
regulation of cell cycleGO:00517261940.044
regulation of phosphate metabolic processGO:0019220810.044
cellular response to organic substanceGO:00713101190.044
response to nutrient levelsGO:0031667350.044
Fly
phosphorus metabolic processGO:00067932320.043
wnt signaling pathwayGO:0016055270.043
cell divisionGO:00513012620.042
cellular protein complex assemblyGO:00436231780.042
regulation of cell motilityGO:2000145570.042
protein phosphorylationGO:0006468850.042
organ morphogenesisGO:0009887670.041
response to other organismGO:00517071010.041
Fly
dna metabolic processGO:0006259740.041
organic cyclic compound biosynthetic processGO:19013621950.041
behaviorGO:00076105270.041
regulation of cellular component movementGO:0051270620.040
regulation of cell deathGO:0010941650.040
aromatic compound biosynthetic processGO:00194381920.040
establishment of localization in cellGO:00516493180.040
regulation of catalytic activityGO:0050790780.039
regulation of organ morphogenesisGO:200002740.039
phagocytosisGO:00069091150.039
regulation of transportGO:0051049910.039
regulation of developmental growthGO:00486383890.038
regulation of phosphorus metabolic processGO:0051174810.038
positive regulation of multicellular organism growthGO:00400183520.037
system processGO:00030081360.036
regulation of cell communicationGO:00106461760.036
Fly
organic substance transportGO:00717021130.036
macromolecular complex assemblyGO:00650031930.036
protein localizationGO:00081042050.036
developmental growthGO:00485894120.035
phosphate containing compound metabolic processGO:00067962320.035
positive regulation of neurogenesisGO:005076940.035
membrane organizationGO:00610241350.035
regulation of endocytosisGO:0030100250.035
response to chemicalGO:00422213560.034
striated muscle cell differentiationGO:00511461580.034
nucleobase containing compound metabolic processGO:00061394060.034
small gtpase mediated signal transductionGO:0007264320.034
regulation of intracellular signal transductionGO:1902531770.034
Fly
meiotic chromosome segregationGO:00451321390.033
protein complex assemblyGO:00064611860.033
cellular nitrogen compound biosynthetic processGO:00442711920.032
digestive tract developmentGO:00485651220.032
regulation of macromolecule metabolic processGO:00602554210.032
histone modificationGO:0016570300.032
protein modification by small protein conjugation or removalGO:0070647400.032
regulation of nucleobase containing compound metabolic processGO:00192192220.032
positive regulation of gene expressionGO:00106281120.031
male gamete generationGO:0048232410.031
cellular macromolecule catabolic processGO:0044265730.031
protein complex subunit organizationGO:00718222800.031
asymmetric cell divisionGO:0008356360.030
response to external biotic stimulusGO:00432071010.030
Fly
response to topologically incorrect proteinGO:0035966820.030
regulation of catabolic processGO:0009894570.030
Fly
epithelium developmentGO:0060429680.030
transcription dna templatedGO:00063511680.030
cell part morphogenesisGO:00329901520.030
regulation of protein metabolic processGO:0051246810.029
signal transductionGO:00071653170.029
Fly
positive regulation of growthGO:00459273690.028
regulation of molecular functionGO:0065009890.028
regenerationGO:003109940.028
transmembrane transportGO:00550851100.028
collagen and cuticulin based cuticle developmentGO:0040002990.028
microtubule based processGO:00070171820.028
regulation of protein import into nucleusGO:004230630.028
modification dependent protein catabolic processGO:0019941320.028
epidermis morphogenesisGO:004873070.028
negative regulation of cell cycleGO:0045786530.027
nucleobase containing compound biosynthetic processGO:00346541840.027
positive regulation of protein metabolic processGO:0051247450.027
negative regulation of cellular processGO:00485232390.027
Fly
regulation of cell proliferationGO:00421271050.027
striated muscle cell developmentGO:00550021570.027
tissue morphogenesisGO:0048729650.027
response to organic substanceGO:00100331310.026
cell cycle g1 s phase transitionGO:004484320.026
ras protein signal transductionGO:0007265310.026
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.025
nucleoside metabolic processGO:0009116990.025
dauer larval developmentGO:0040024920.025
organonitrogen compound catabolic processGO:1901565900.025
positive regulation of phosphorus metabolic processGO:0010562560.025
muscle cell developmentGO:00550011580.025
organonitrogen compound metabolic processGO:19015641510.025
cellular component morphogenesisGO:00329893180.025
positive regulation of phosphate metabolic processGO:0045937560.025
gene expressionGO:00104674120.024
muscle structure developmentGO:00610611910.024
regulation of cell differentiationGO:0045595810.024
regulation of apoptotic signaling pathwayGO:200123310.024
actomyosin structure organizationGO:00310321540.024
neurological system processGO:0050877530.024
phosphorylationGO:00163101160.024
regulation of response to stressGO:0080134280.023
Fly
axon developmentGO:00615641630.023
lipid metabolic processGO:0006629770.023
proteolysis involved in cellular protein catabolic processGO:0051603320.023
regulation of cytoplasmic transportGO:190364930.023
stress activated protein kinase signaling cascadeGO:0031098100.023
regulation of response to woundingGO:190303410.023
embryonic morphogenesisGO:00485981520.023
regulation of behaviorGO:0050795970.022
posttranscriptional regulation of gene expressionGO:00106081660.022
membrane invaginationGO:0010324980.022
regulation of gene expressionGO:00104683660.022
regulation of phosphorylationGO:0042325450.022
neuromuscular junction developmentGO:000752820.022
negative regulation of gene expression epigeneticGO:004581420.022
positive regulation of nucleobase containing compound metabolic processGO:00459351340.021
regulation of nucleocytoplasmic transportGO:004682230.021
response to unfolded proteinGO:0006986710.021
purine ribonucleoside metabolic processGO:0046128920.021
establishment of mitotic spindle orientationGO:0000132280.021
rna metabolic processGO:00160702280.021
regulation of cellular metabolic processGO:00313233050.021
Fly
dephosphorylationGO:0016311170.020
er nucleus signaling pathwayGO:0006984660.020
tube developmentGO:00352951260.020
protein neddylationGO:004511630.020
g1 s transition of mitotic cell cycleGO:000008220.020
positive regulation of cell migrationGO:003033530.020
negative regulation of rna biosynthetic processGO:1902679530.020
enzyme linked receptor protein signaling pathwayGO:0007167500.020
negative regulation of cell communicationGO:0010648610.020
Fly
endoderm developmentGO:0007492200.020
amine metabolic processGO:0009308150.019
positive regulation of cell deathGO:0010942380.019
regulation of nitrogen compound metabolic processGO:00511712220.019
signal transduction by phosphorylationGO:0023014310.019
developmental inductionGO:003112810.019
multi organism reproductive behaviorGO:00447053870.019
negative regulation of metabolic processGO:00098922400.019
regulation of localizationGO:00328791940.019
positive regulation of cell morphogenesis involved in differentiationGO:001077040.019
muscle cell differentiationGO:00426921710.019
cellular macromolecule localizationGO:0070727750.019
cell morphogenesis involved in differentiationGO:00009041120.019
regulation of cellular biosynthetic processGO:00313261890.019
regulation of cell migrationGO:0030334550.018
cell proliferationGO:00082831160.018
cell fate commitment involved in formation of primary germ layerGO:0060795330.018
regulation of cellular ketone metabolic processGO:001056530.018
response to starvationGO:0042594260.018
Fly
cellular lipid metabolic processGO:0044255400.018
chromatin organizationGO:0006325320.018
regulation of cellular amine metabolic processGO:003323800.018
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161200.018
myofibril assemblyGO:00302391540.018
regulation of cellular amino acid metabolic processGO:000652100.018
regulation of protein stabilityGO:003164730.018
cell surface receptor signaling pathwayGO:00071661490.018
ribonucleoprotein complex assemblyGO:002261840.018
rna biosynthetic processGO:00327741690.018
cell cell signalingGO:00072671180.017
rna interferenceGO:00162461370.017
regulation of rna metabolic processGO:00512521730.017
single organism cellular localizationGO:1902580720.017
organic cyclic compound catabolic processGO:19013611190.017
protein complex biogenesisGO:00702711860.017
axonogenesisGO:00074091020.017
actin cytoskeleton organizationGO:00300361840.017
cellular amine metabolic processGO:0044106150.017
positive regulation of catalytic activityGO:0043085590.017
negative regulation of response to stimulusGO:0048585730.017
Fly
regulation of protein ubiquitinationGO:003139630.017
positive regulation of protein modification processGO:0031401290.017
regulation of protein targetingGO:190353330.016
intracellular receptor signaling pathwayGO:003052220.016
muscle tissue developmentGO:006053710.016
phagocytosis engulfmentGO:0006911980.016
protein oligomerizationGO:005125940.016
response to bacteriumGO:0009617860.016
neuron projection morphogenesisGO:00488121140.016
positive regulation of cellular protein catabolic processGO:190336430.016
gene silencing by rnaGO:00310471430.016
positive regulation of neuron differentiationGO:004566640.016
cell projection morphogenesisGO:00488581480.015
positive regulation of protein transportGO:005122240.015
positive regulation of apoptotic processGO:0043065170.015
protein modification by small protein conjugationGO:0032446310.015
oocyte constructionGO:000730820.015
cellular ketone metabolic processGO:0042180140.015
meiosis iGO:0007127190.015
negative regulation of biosynthetic processGO:0009890650.015
regulation of mitotic cell cycle embryonicGO:000979450.015
cellular protein localizationGO:0034613750.015
positive regulation of stress activated protein kinase signaling cascadeGO:007030430.015
positive regulation of cellular biosynthetic processGO:00313281090.015
positive regulation of programmed cell deathGO:0043068270.015
positive regulation of cell projection organizationGO:003134640.015
positive regulation of cellular component organizationGO:0051130340.015
carboxylic acid metabolic processGO:0019752340.015
negative regulation of cellular metabolic processGO:0031324950.015
negative regulation of signal transductionGO:0009968600.015
Fly
regionalizationGO:0003002310.015
heterocycle biosynthetic processGO:00181301870.015
negative regulation of mitotic cell cycle phase transitionGO:190199150.015
positive regulation of catabolic processGO:0009896380.015
cell type specific apoptotic processGO:009728540.015
regulation of cellular response to stressGO:0080135190.015
cuticle developmentGO:00423351000.015
regulation of protein localizationGO:0032880500.014
myosin filament organizationGO:00310331380.014
nucleobase containing compound catabolic processGO:00346551140.014
regulation of cellular localizationGO:0060341420.014
negative regulation of neurogenesisGO:005076840.014
negative regulation of cell cycle processGO:0010948120.014
establishment of organelle localizationGO:00516561230.014
cell cycle phase transitionGO:0044770190.014
defense response to bacteriumGO:0042742860.014
pattern specification processGO:0007389590.014
myosin filament assemblyGO:00310341380.014
inductive cell migrationGO:00400391450.013
regulation of cytoskeleton organizationGO:0051493410.013
oocyte axis specificationGO:000730920.013
nucleic acid metabolic processGO:00903042990.013
negative regulation of gene expressionGO:00106292170.013
positive regulation of rna metabolic processGO:00512541030.013
response to endoplasmic reticulum stressGO:0034976710.013
regulation of transcription from rna polymerase ii promoterGO:00063571450.013
positive regulation of response to stimulusGO:0048584550.013
insulin receptor signaling pathwayGO:0008286140.013
negative regulation of nucleic acid templated transcriptionGO:1903507530.013
single organism biosynthetic processGO:0044711910.013
regulation of vesicle mediated transportGO:0060627270.013
organelle localizationGO:00516401270.013
endoplasmic reticulum unfolded protein responseGO:0030968660.013
regulation of sequence specific dna binding transcription factor activityGO:005109030.012
mapk cascadeGO:0000165310.012
engulfment of apoptotic cellGO:0043652940.012
nucleic acid templated transcriptionGO:00976591690.012
regulation of lipid biosynthetic processGO:004689010.012
regulation of meiosisGO:0040020940.012
positive regulation of vulval developmentGO:0040026520.012
positive regulation of intracellular protein transportGO:009031620.012
ribose phosphate metabolic processGO:0019693990.012
lamellipodium assemblyGO:003003220.012
regulation of lipid metabolic processGO:001921640.012
cellular response to unfolded proteinGO:0034620710.012
single organism membrane organizationGO:0044802350.012
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.012
cell recognitionGO:0008037850.012
regulation of nucleic acid templated transcriptionGO:19035061650.012
nucleoside catabolic processGO:0009164780.012
maintenance of protein location in cellGO:0032507120.012
cell morphogenesis involved in neuron differentiationGO:00486671110.012
organophosphate metabolic processGO:00196371250.012
proteasomal protein catabolic processGO:0010498200.011
striated muscle myosin thick filament assemblyGO:00716881380.011
protein transportGO:0015031450.011
positive regulation of macromolecule biosynthetic processGO:00105571090.011
regulation of protein catabolic processGO:0042176130.011
negative regulation of response to external stimulusGO:003210230.011
regulation of proteolysis involved in cellular protein catabolic processGO:190305050.011
developmental maturationGO:0021700260.011
digestive system developmentGO:00551231220.011
positive regulation of sequence specific dna binding transcription factor activityGO:005109120.011
response to oxygen containing compoundGO:1901700440.011
regulation of cellular component biogenesisGO:0044087260.011
stress activated mapk cascadeGO:0051403100.011
cytokinesisGO:0000910800.011
negative regulation of cellular biosynthetic processGO:0031327650.011
mitotic spindle organizationGO:0007052810.011
organic acid metabolic processGO:0006082470.010
regulation of canonical wnt signaling pathwayGO:006082810.010
regulation of cellular catabolic processGO:0031329510.010
Fly
positive regulation of proteasomal protein catabolic processGO:190180010.010
asymmetric protein localizationGO:0008105350.010
regulation of mapk cascadeGO:0043408230.010
epithelial cell proliferationGO:005067310.010
regulation of transcription dna templatedGO:00063551640.010
positive regulation of intracellular transportGO:003238820.010
oxidation reduction processGO:0055114590.010

atg-18 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
nervous system diseaseDOID:86300.014
cardiovascular system diseaseDOID:128700.011
disease of cellular proliferationDOID:1456600.011
muscular diseaseDOID:008000000.010
myopathyDOID:42300.010
heart diseaseDOID:11400.010
cardiomyopathyDOID:005070000.010
muscle tissue diseaseDOID:6600.010
musculoskeletal system diseaseDOID:1700.010