Caenorhabditis elegans

166 known processes

unc-53 (CELE_F45E10.1)

Protein UNC-53

unc-53 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
single organism reproductive processGO:004470211960.928
sexual reproductionGO:00199535460.918
locomotionGO:004001116340.902
cell projection organizationGO:00300302310.893
cell part morphogenesisGO:00329901520.885
multicellular organismal reproductive processGO:00486098150.881
multi organism reproductive processGO:00447038670.877
multicellular organism reproductionGO:00325048190.875
embryo developmentGO:000979030520.868
cell developmentGO:00484686960.843
reproductive structure developmentGO:00486088500.813
neurogenesisGO:00220082360.787
establishment of localizationGO:005123411710.783
neuron differentiationGO:00301822170.772
behaviorGO:00076105270.765
transportGO:000681010930.758
regulation of cell developmentGO:0060284490.750
developmental process involved in reproductionGO:000300611650.745
reproductive behaviorGO:00190983870.740
reproductive system developmentGO:00614588500.737
embryonic morphogenesisGO:00485981520.722
embryo development ending in birth or egg hatchingGO:000979229920.708
nervous system developmentGO:00073992530.673
ovipositionGO:00189913640.647
matingGO:0007618340.636
cell cell signalingGO:00072671180.630
positive regulation of nematode larval developmentGO:0061063540.590
sex differentiationGO:00075489090.580
gamete generationGO:00072764610.554
post embryonic developmentGO:000979121520.554
cellular process involved in reproduction in multicellular organismGO:00224123510.543
axon developmentGO:00615641630.531
regulation of cell differentiationGO:0045595810.520
multi multicellular organism processGO:00447063900.516
single organism transportGO:00447654470.510
cell motilityGO:00488703130.499
regulation of developmental processGO:00507936840.489
receptor mediated endocytosisGO:00068987150.486
rna metabolic processGO:00160702280.476
regulation of multicellular organismal processGO:00512397260.474
head developmentGO:006032210.474
cellular component morphogenesisGO:00329893180.471
germ cell developmentGO:00072813510.464
cell projection morphogenesisGO:00488581480.462
mating behaviorGO:0007617320.455
organ developmentGO:004851311020.447
oogenesisGO:00484772290.444
single organism organelle organizationGO:19025895010.430
multi organism reproductive behaviorGO:00447053870.423
cell morphogenesisGO:00009021630.420
cell morphogenesis involved in neuron differentiationGO:00486671110.410
gonad developmentGO:00084068400.397
taxisGO:00423301280.396
neuron recognitionGO:0008038830.382
regulation of cellular metabolic processGO:00313233050.379
neuron projection developmentGO:00311751870.363
genitalia developmentGO:00488067410.362
endocytosisGO:00068978190.361
multi organism behaviorGO:00517053890.351
epithelial tube morphogenesisGO:006056210.350
positive regulation of locomotionGO:0040017420.349
cellular component assemblyGO:00226072930.341
regulation of cell morphogenesis involved in differentiationGO:0010769290.336
cellular response to chemical stimulusGO:00708871290.331
female gamete generationGO:00072922540.325
protein complex subunit organizationGO:00718222800.324
single organism localizationGO:19025785180.316
cell migrationGO:00164773060.313
post embryonic organ developmentGO:00485693360.312
protein metabolic processGO:00195384220.309
single organism signalingGO:00447004010.303
nucleic acid templated transcriptionGO:00976591690.303
programmed cell deathGO:00125015000.300
anatomical structure formation involved in morphogenesisGO:00486462500.298
macromolecule catabolic processGO:00090572020.283
multicellular organismal agingGO:00102598120.281
positive regulation of neuron differentiationGO:004566640.278
regulation of nucleobase containing compound metabolic processGO:00192192220.273
multicellular organismal reproductive behaviorGO:00330573840.272
regulation of neuron projection developmentGO:0010975310.270
protein modification processGO:00362112070.266
cellular macromolecule biosynthetic processGO:00346452470.264
organelle organizationGO:00069967830.262
single organism behaviorGO:0044708830.254
catabolic processGO:00090563180.254
hermaphrodite genitalia developmentGO:00400357340.248
positive regulation of vulval developmentGO:0040026520.248
regulation of macromolecule biosynthetic processGO:00105561890.243
positive regulation of cell projection organizationGO:003134640.243
signalingGO:00230524010.242
neurotransmitter transportGO:0006836320.239
regulation of synaptic transmissionGO:0050804340.236
protein catabolic processGO:00301631620.235
negative regulation of biological processGO:00485195670.230
regulation of macromolecule metabolic processGO:00602554210.228
developmental growthGO:00485894120.225
purine nucleoside catabolic processGO:0006152750.221
response to chemicalGO:00422213560.220
determination of adult lifespanGO:00083408120.217
regulation of metabolic processGO:00192224780.216
regulation of primary metabolic processGO:00800902920.210
tissue morphogenesisGO:0048729650.207
organic substance catabolic processGO:19015752940.202
purine ribonucleotide metabolic processGO:0009150950.201
regulation of biological qualityGO:00650087410.200
neuron developmentGO:00486661990.198
generation of neuronsGO:00486992350.197
positive regulation of cell morphogenesis involved in differentiationGO:001077040.193
axon guidanceGO:0007411820.191
gene expressionGO:00104674120.184
tube morphogenesisGO:0035239790.184
regulation of gene expressionGO:00104683660.184
dendrite developmentGO:0016358420.182
regulation of cellular component organizationGO:00511282480.182
heterocycle catabolic processGO:00467001190.180
regulation of phosphorus metabolic processGO:0051174810.180
signal transductionGO:00071653170.180
protein phosphorylationGO:0006468850.176
agingGO:00075688120.175
regulation of locomotionGO:00400121610.174
positive regulation of macromolecule metabolic processGO:00106041490.173
phosphate containing compound metabolic processGO:00067962320.171
positive regulation of cellular processGO:00485223320.171
negative regulation of cellular processGO:00485232390.168
nucleobase containing compound metabolic processGO:00061394060.168
muscle contractionGO:0006936430.167
regulation of neuron differentiationGO:0045664400.167
regulation of cell morphogenesisGO:0022604400.167
epithelium developmentGO:0060429680.164
cell cycleGO:00070495260.164
positive regulation of cellular metabolic processGO:00313251780.163
macromolecular complex subunit organizationGO:00439333200.161
positive regulation of gtpase activityGO:0043547280.159
regulation of multicellular organismal developmentGO:20000263170.158
negative regulation of macromolecule metabolic processGO:00106052290.157
regulation of purine nucleotide catabolic processGO:0033121350.157
cytoskeleton organizationGO:00070103390.157
system processGO:00030081360.155
apoptotic processGO:00069154780.155
growthGO:00400075620.154
positive regulation of nitrogen compound metabolic processGO:00511731340.154
positive regulation of organ growthGO:004662240.151
heterocycle biosynthetic processGO:00181301870.148
macromolecule localizationGO:00330367710.148
oocyte differentiationGO:0009994450.147
synaptic transmissionGO:00072681060.144
establishment of organelle localizationGO:00516561230.142
positive regulation of neuron projection developmentGO:001097640.142
microtubule based processGO:00070171820.139
regulation of response to stimulusGO:00485832430.138
regulation of vulval developmentGO:00400282480.138
ion transportGO:00068111130.138
cellular nitrogen compound biosynthetic processGO:00442711920.137
negative regulation of metabolic processGO:00098922400.134
nucleic acid metabolic processGO:00903042990.133
negative regulation of multicellular organismal processGO:00512412360.131
neuron projection morphogenesisGO:00488121140.130
oocyte developmentGO:0048599440.128
macromolecular complex assemblyGO:00650031930.128
development of primary sexual characteristicsGO:00451378400.124
regulation of anatomical structure sizeGO:0090066460.121
regulation of rna biosynthetic processGO:20011411650.121
regulation of cell fate specificationGO:0042659220.121
regulation of phosphate metabolic processGO:0019220810.121
signal transduction by phosphorylationGO:0023014310.118
regulation of nucleoside metabolic processGO:0009118370.118
cellular component biogenesisGO:00440852970.116
digestive tract developmentGO:00485651220.115
regulation of catalytic activityGO:0050790780.113
cellular macromolecular complex assemblyGO:00346221840.112
phosphorus metabolic processGO:00067932320.112
olfactory behaviorGO:0042048270.108
regulation of cell communicationGO:00106461760.106
negative regulation of cellular protein metabolic processGO:0032269270.106
positive regulation of gene expressionGO:00106281120.106
developmental cell growthGO:0048588390.105
organ morphogenesisGO:0009887670.105
Zebrafish
deathGO:00162655470.105
vulval developmentGO:00400253330.103
body morphogenesisGO:00101716200.102
vesicle mediated transportGO:00161928520.100
tissue developmentGO:00098881120.099
cell deathGO:00082195470.099
negative regulation of developmental processGO:00510932270.098
positive regulation of multicellular organismal processGO:00512404170.098
cell cycle processGO:00224024820.097
establishment of localization in cellGO:00516493180.097
positive regulation of developmental processGO:00510944080.097
regulation of transcription from rna polymerase ii promoterGO:00063571450.095
intracellular signal transductionGO:0035556960.095
chemotaxisGO:00069351200.094
regulation of neurotransmitter levelsGO:0001505360.094
gastrulationGO:0007369580.093
mapk cascadeGO:0000165310.093
cellular protein complex assemblyGO:00436231780.090
purine containing compound metabolic processGO:0072521950.090
positive regulation of nucleotide catabolic processGO:0030813280.090
negative regulation of locomotionGO:0040013210.090
positive regulation of growthGO:00459273690.088
axonogenesisGO:00074091020.088
regulation of cell fate commitmentGO:0010453220.087
regulation of neurotransmitter secretionGO:0046928160.087
regulation of neurogenesisGO:0050767400.086
nucleotide catabolic processGO:0009166770.086
regulation of nematode larval developmentGO:00610622600.084
negative regulation of cellular metabolic processGO:0031324950.084
anatomical structure homeostasisGO:0060249110.083
adult behaviorGO:003053430.083
detection of external stimulusGO:000958140.082
secretionGO:00469031470.081
cell surface receptor signaling pathwayGO:00071661490.079
cellular component movementGO:00069283880.079
rna biosynthetic processGO:00327741690.078
macromolecule biosynthetic processGO:00090592500.078
regulation of signalingGO:00230511720.076
negative regulation of nucleobase containing compound metabolic processGO:0045934630.076
guanosine containing compound catabolic processGO:1901069480.075
regulation of transcription dna templatedGO:00063551640.075
response to mechanical stimulusGO:0009612280.075
regulation of cellular macromolecule biosynthetic processGO:20001121880.074
regulation of localizationGO:00328791940.074
neuron projection guidanceGO:0097485820.074
positive regulation of nucleotide metabolic processGO:0045981280.074
cellular protein modification processGO:00064642070.073
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.073
response to external stimulusGO:00096052890.073
neurological system processGO:0050877530.072
transcription from rna polymerase ii promoterGO:00063661490.072
cellular component assembly involved in morphogenesisGO:00109271830.071
organelle assemblyGO:00709252140.071
nucleoside triphosphate metabolic processGO:0009141870.071
cation transportGO:0006812780.071
regulation of system processGO:0044057270.071
positive regulation of nucleobase containing compound metabolic processGO:00459351340.070
purine nucleoside triphosphate metabolic processGO:0009144870.070
sensory organ morphogenesisGO:009059620.070
regulation of nitrogen compound metabolic processGO:00511712220.070
positive regulation of macromolecule biosynthetic processGO:00105571090.070
lipid localizationGO:00108765730.068
single organism catabolic processGO:00447121290.068
striated muscle cell developmentGO:00550021570.068
positive regulation of metabolic processGO:00098931870.067
cell recognitionGO:0008037850.067
regulation of organelle organizationGO:00330431640.067
pattern specification processGO:0007389590.066
cilium morphogenesisGO:0060271330.066
nucleobase containing small molecule metabolic processGO:00550861150.065
mitotic cell cycle processGO:19030471940.064
cellular protein metabolic processGO:00442672790.064
negative regulation of post embryonic developmentGO:00485812080.064
establishment of cell polarityGO:0030010460.064
protein complex assemblyGO:00064611860.064
neurotransmitter secretionGO:0007269260.063
digestive tract morphogenesisGO:0048546760.063
positive regulation of nucleoside metabolic processGO:0045979280.062
regulation of biosynthetic processGO:00098891890.062
ras protein signal transductionGO:0007265310.062
regulation of signal transductionGO:00099661350.061
purine ribonucleoside metabolic processGO:0046128920.061
nucleoside phosphate catabolic processGO:1901292770.061
protein complex biogenesisGO:00702711860.061
establishment of spindle localizationGO:0051293510.060
cell morphogenesis involved in differentiationGO:00009041120.060
metal ion transportGO:0030001490.060
lipid storageGO:00199155650.060
regulation of nucleic acid templated transcriptionGO:19035061650.059
purine nucleotide metabolic processGO:0006163950.059
regulation of oocyte maturationGO:190019370.058
mitotic spindle organizationGO:0007052810.057
transcription dna templatedGO:00063511680.056
regulation of muscle contractionGO:0006937200.056
establishment of mitotic spindle orientationGO:0000132280.056
protein localizationGO:00081042050.056
secretion by cellGO:00329401380.056
regulation of programmed cell deathGO:0043067500.056
cell growthGO:0016049440.055
adult locomotory behaviorGO:000834410.055
purine ribonucleotide catabolic processGO:0009154750.055
nucleobase containing compound catabolic processGO:00346551140.054
cellular localizationGO:00516413600.054
regulation of rna metabolic processGO:00512521730.054
regulation of post embryonic developmentGO:00485802600.053
nucleotide metabolic processGO:00091171080.053
defense responseGO:00069522960.052
positive regulation of rna biosynthetic processGO:19026801020.052
biosynthetic processGO:00090583230.052
regulation of cellular protein metabolic processGO:0032268750.052
maintenance of locationGO:00512355800.051
negative regulation of nucleic acid templated transcriptionGO:1903507530.051
homeostatic processGO:0042592510.050
positive regulation of developmental growthGO:00486393540.050
multicellular organism growthGO:00352643850.050
establishment of protein localization to membraneGO:009015030.050
positive regulation of cellular biosynthetic processGO:00313281090.049
actin cytoskeleton organizationGO:00300361840.049
developmental growth involved in morphogenesisGO:0060560370.049
regulation of cell cycle processGO:00105641450.048
organophosphate catabolic processGO:0046434810.047
cell fate commitment involved in formation of primary germ layerGO:0060795330.047
organic cyclic compound biosynthetic processGO:19013621950.047
establishment of mitotic spindle localizationGO:0040001410.047
regulation of organ morphogenesisGO:200002740.047
organic cyclic compound catabolic processGO:19013611190.047
small molecule metabolic processGO:00442811860.046
regulation of cytoskeleton organizationGO:0051493410.046
ribonucleotide catabolic processGO:0009261750.046
purine ribonucleoside triphosphate metabolic processGO:0009205870.046
muscle cell developmentGO:00550011580.046
regulation of developmental growthGO:00486383890.046
embryonic pattern specificationGO:0009880210.046
regulation of nucleotide catabolic processGO:0030811350.045
establishment of vesicle localizationGO:0051650230.045
organic substance biosynthetic processGO:19015763230.044
organic substance transportGO:00717021130.044
small gtpase mediated signal transductionGO:0007264320.044
purine nucleoside triphosphate catabolic processGO:0009146720.044
cellular biosynthetic processGO:00442493150.044
mesoderm morphogenesisGO:0048332240.043
cognitionGO:0050890270.043
purine ribonucleoside catabolic processGO:0046130750.043
striated muscle cell differentiationGO:00511461580.042
nucleoside phosphate metabolic processGO:00067531080.042
regulation of transportGO:0051049910.042
cilium organizationGO:0044782320.042
striated muscle myosin thick filament assemblyGO:00716881380.042
regulation of nervous system developmentGO:0051960410.042
response to organic substanceGO:00100331310.041
ribonucleoside triphosphate catabolic processGO:0009203720.041
actin filament based processGO:00300291910.041
cellular protein localizationGO:0034613750.041
dorsal ventral axon guidanceGO:0033563190.041
positive regulation of neurogenesisGO:005076940.040
regulation of gtp catabolic processGO:0033124320.040
regulation of multicellular organism growthGO:00400143730.039
regulation of axon extensionGO:0030516200.039
regulation of extent of cell growthGO:0061387200.039
monovalent inorganic cation transportGO:0015672330.039
sensory perception of chemical stimulusGO:0007606150.039
male mating behaviorGO:0060179260.039
regulation of growthGO:00400084090.039
regulation of protein metabolic processGO:0051246810.038
muscle fiber developmentGO:004874720.038
spindle organizationGO:0007051920.038
signal releaseGO:0023061280.038
positive regulation of multicellular organism growthGO:00400183520.037
negative regulation of neurogenesisGO:005076840.037
positive regulation of purine nucleotide metabolic processGO:1900544280.037
muscle system processGO:0003012430.037
macromolecule modificationGO:00434122180.037
carbohydrate derivative metabolic processGO:19011351410.037
localization of cellGO:00516743130.037
regulation of synapse assemblyGO:005196320.037
establishment or maintenance of cell polarityGO:0007163630.036
negative regulation of cellular component organizationGO:0051129330.036
cilium assemblyGO:0042384280.036
organonitrogen compound catabolic processGO:1901565900.036
regulation of cellular component sizeGO:0032535400.036
developmental inductionGO:003112810.035
synaptic vesicle transportGO:0048489210.035
chemosensory behaviorGO:0007635330.035
regulation of cell cycleGO:00517261940.035
regulation of hydrolase activityGO:0051336450.035
positive regulation of phosphorus metabolic processGO:0010562560.035
positive regulation of gtp catabolic processGO:0033126280.035
intercellular transportGO:001049610.035
ribonucleoside triphosphate metabolic processGO:0009199870.034
mesodermal cell differentiationGO:0048333150.034
rho protein signal transductionGO:000726620.034
negative regulation of rna metabolic processGO:0051253530.034
cellular nitrogen compound catabolic processGO:00442701190.034
negative regulation of nitrogen compound metabolic processGO:0051172630.034
spindle localizationGO:0051653510.034
regulation of gastrulationGO:001047040.034
organelle localizationGO:00516401270.034
nucleobase containing compound biosynthetic processGO:00346541840.033
phosphorylationGO:00163101160.033
posttranscriptional regulation of gene expressionGO:00106081660.033
regulation of phosphorylationGO:0042325450.033
ribose phosphate metabolic processGO:0019693990.033
calcium mediated signalingGO:001972230.033
mitotic nuclear divisionGO:0007067890.032
regulation of mapk cascadeGO:0043408230.032
glycosyl compound metabolic processGO:19016571000.032
muscle cell differentiationGO:00426921710.032
regulation of nucleotide metabolic processGO:0006140370.032
purine containing compound catabolic processGO:0072523750.032
pharyngeal pumpingGO:0043050580.031
negative regulation of gene expressionGO:00106292170.031
regulation of mesoderm developmentGO:200038020.031
regulation of gtpase activityGO:0043087300.031
cell maturationGO:0048469260.031
ribonucleoside metabolic processGO:0009119980.031
positive regulation of axonogenesisGO:005077240.031
regulation of multi organism processGO:0043900690.031
regulation of protein stabilityGO:003164730.030
guanosine containing compound metabolic processGO:1901068490.030
negative regulation of protein serine threonine kinase activityGO:007190160.030
mechanosensory behaviorGO:0007638250.030
defense response to other organismGO:00985421000.030
regulation of intracellular signal transductionGO:1902531770.030
muscle organ developmentGO:0007517260.029
regulation of purine nucleotide metabolic processGO:1900542370.029
purine ribonucleoside triphosphate catabolic processGO:0009207720.029
actomyosin structure organizationGO:00310321540.029
regulation of ras protein signal transductionGO:0046578410.029
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.029
neuron projection extensionGO:1990138370.029
potassium ion transportGO:0006813210.029
cell proliferationGO:00082831160.029
regulation of g protein coupled receptor protein signaling pathwayGO:000827740.028
regulation of anatomical structure morphogenesisGO:0022603510.028
negative regulation of macromolecule biosynthetic processGO:0010558650.028
myosin filament assemblyGO:00310341380.027
glycosyl compound catabolic processGO:1901658790.027
g protein coupled receptor signaling pathwayGO:0007186460.027
positive regulation of rna metabolic processGO:00512541030.027
regulation of protein kinase activityGO:0045859280.027
response to inorganic substanceGO:0010035500.026
organelle fissionGO:00482853630.026
chromosome organizationGO:00512761040.026
aromatic compound biosynthetic processGO:00194381920.026
negative regulation of axon extensionGO:003051720.026
response to abiotic stimulusGO:00096281520.026
regulation of cellular biosynthetic processGO:00313261890.026
negative regulation of nematode larval developmentGO:00610642080.025
feeding behaviorGO:0007631700.025
apoptotic cell clearanceGO:00432771110.025
cellular catabolic processGO:00442481990.025
regulation of organ growthGO:004662050.025
regulation of atp catabolic processGO:190328930.025
nucleoside catabolic processGO:0009164780.025
muscle tissue developmentGO:006053710.024
intracellular transportGO:0046907770.024
molting cycleGO:00423032810.024
axon extensionGO:0048675370.024
nucleoside metabolic processGO:0009116990.024
positive regulation of epithelial cell proliferationGO:005067910.024
filopodium assemblyGO:004684720.024
muscle organ morphogenesisGO:004864440.024
regulation of nuclear divisionGO:00517831150.024
regulation of cell motilityGO:2000145570.024
positive regulation of biosynthetic processGO:00098911090.023
regulation of transferase activityGO:0051338310.023
positive regulation of catabolic processGO:0009896380.023
cellular response to organic substanceGO:00713101190.023
oocyte constructionGO:000730820.023
negative regulation of signalingGO:0023057610.023
myosin filament organizationGO:00310331380.023
sleepGO:003043140.022
regulation of epithelial cell differentiationGO:003085640.022
organophosphate metabolic processGO:00196371250.022
ribonucleotide metabolic processGO:0009259990.022
regulation of cell sizeGO:0008361300.022
cellular response to abiotic stimulusGO:007121440.022
regulation of kinase activityGO:0043549290.022
regulation of cell divisionGO:00513021420.022
regulation of protein serine threonine kinase activityGO:0071900180.022
single organism cellular localizationGO:1902580720.022
neuroblast divisionGO:005505790.022
canonical wnt signaling pathwayGO:006007030.021
defense response to gram negative bacteriumGO:0050829640.021
membrane depolarizationGO:005189910.021
epithelial cell differentiationGO:0030855170.021
negative regulation of vulval developmentGO:00400272060.021
response to endogenous stimulusGO:0009719330.021
regulation of ovipositionGO:0046662430.021
response to external biotic stimulusGO:00432071010.021
positive regulation of cell migrationGO:003033530.020
positive regulation of lipase activityGO:006019320.020
glutamate receptor signaling pathwayGO:000721520.020
response to woundingGO:000961140.019
enzyme linked receptor protein signaling pathwayGO:0007167500.019
myofibril assemblyGO:00302391540.019
digestive system developmentGO:00551231220.019
tube developmentGO:00352951260.019
negative regulation of axonogenesisGO:005077120.019
regulation of neuromuscular synaptic transmissionGO:190007310.019
developmental maturationGO:0021700260.018
establishment of spindle orientationGO:0051294340.018
regulation of neurotransmitter transportGO:0051588160.018
response to bacteriumGO:0009617860.018
regulation of cytoplasmic transportGO:190364930.018
negative regulation of cell communicationGO:0010648610.018
regulation of development heterochronicGO:0040034180.018
purine nucleoside metabolic processGO:0042278920.018
positive regulation of cell communicationGO:0010647690.018
regulation of cellular ketone metabolic processGO:001056530.018
defense response to bacteriumGO:0042742860.018
positive regulation of signalingGO:0023056660.018
axonal fasciculationGO:0007413790.018
synaptic growth at neuromuscular junctionGO:005112410.017

unc-53 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.103
organ system cancerDOID:005068600.054
cancerDOID:16200.054
disease of cellular proliferationDOID:1456600.054
nervous system diseaseDOID:86300.020
female reproductive organ cancerDOID:12000.019
reproductive organ cancerDOID:19300.019
gastrointestinal system cancerDOID:311900.018