Caenorhabditis elegans

86 known processes

paa-1 (CELE_F48E8.5)

Protein PAA-1

paa-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to endoplasmic reticulum stressGO:0034976710.587
germ cell developmentGO:00072813510.535
post embryonic developmentGO:000979121520.522
developmental process involved in reproductionGO:000300611650.485
locomotionGO:004001116340.476
establishment of localizationGO:005123411710.464
endocytosisGO:00068978190.349
meiotic nuclear divisionGO:00071263000.346
sexual reproductionGO:00199535460.336
multicellular organismal reproductive processGO:00486098150.327
cell cycleGO:00070495260.314
programmed cell deathGO:00125015000.308
embryo development ending in birth or egg hatchingGO:000979229920.306
regulation of developmental processGO:00507936840.280
multicellular organism reproductionGO:00325048190.270
single organism reproductive processGO:004470211960.270
cellular process involved in reproduction in multicellular organismGO:00224123510.264
cell deathGO:00082195470.253
signalingGO:00230524010.239
Human
body morphogenesisGO:00101716200.234
oogenesisGO:00484772290.222
growthGO:00400075620.219
meiotic cell cycleGO:00513213350.218
multi organism reproductive processGO:00447038670.215
meiotic cell cycle processGO:19030461700.209
nervous system developmentGO:00073992530.205
cell migrationGO:00164773060.205
embryo developmentGO:000979030520.204
single organism organelle organizationGO:19025895010.204
agingGO:00075688120.200
single organism signalingGO:00447004010.185
Human
signal transductionGO:00071653170.183
Human
neurogenesisGO:00220082360.179
protein metabolic processGO:00195384220.178
Yeast
development of primary sexual characteristicsGO:00451378400.176
multicellular organismal agingGO:00102598120.173
gamete generationGO:00072764610.172
macromolecular complex subunit organizationGO:00439333200.171
cytoskeleton organizationGO:00070103390.169
negative regulation of nematode larval developmentGO:00610642080.162
cellular component biogenesisGO:00440852970.160
organ developmentGO:004851311020.159
negative regulation of vulval developmentGO:00400272060.156
cellular component movementGO:00069283880.156
microtubule based processGO:00070171820.155
regulation of vulval developmentGO:00400282480.154
transportGO:000681010930.151
generation of neuronsGO:00486992350.149
vesicle mediated transportGO:00161928520.148
multicellular organism growthGO:00352643850.148
determination of adult lifespanGO:00083408120.148
female gamete generationGO:00072922540.147
regulation of cellular protein metabolic processGO:0032268750.142
Yeast
regulation of biological qualityGO:00650087410.140
negative regulation of biological processGO:00485195670.137
regulation of multicellular organismal processGO:00512397260.136
cellular response to topologically incorrect proteinGO:0035967760.134
regulation of multicellular organismal developmentGO:20000263170.125
regulation of nematode larval developmentGO:00610622600.123
vulval developmentGO:00400253330.122
regulation of developmental growthGO:00486383890.121
cellular protein metabolic processGO:00442672790.120
Yeast
apoptotic processGO:00069154780.116
reproductive structure developmentGO:00486088500.116
response to topologically incorrect proteinGO:0035966820.115
developmental growthGO:00485894120.113
organelle localizationGO:00516401270.112
response to unfolded proteinGO:0006986710.111
mitotic nuclear divisionGO:0007067890.109
positive regulation of growthGO:00459273690.109
cellular response to stressGO:00335541620.108
protein modification processGO:00362112070.107
receptor mediated endocytosisGO:00068987150.107
organelle fissionGO:00482853630.105
regulation of growthGO:00400084090.104
fertilizationGO:0009566630.102
positive regulation of multicellular organism growthGO:00400183520.101
negative regulation of cellular processGO:00485232390.098
Yeast
endoplasmic reticulum unfolded protein responseGO:0030968660.097
gonad developmentGO:00084068400.097
protein complex biogenesisGO:00702711860.095
cell developmentGO:00484686960.095
Human
cellular protein modification processGO:00064642070.095
single fertilizationGO:0007338610.094
genitalia developmentGO:00488067410.093
system processGO:00030081360.091
deathGO:00162655470.091
positive regulation of developmental processGO:00510944080.091
cellular component assemblyGO:00226072930.090
axon developmentGO:00615641630.090
single organism localizationGO:19025785180.088
cellular response to unfolded proteinGO:0034620710.087
positive regulation of cellular metabolic processGO:00313251780.086
meiotic chromosome segregationGO:00451321390.086
maintenance of locationGO:00512355800.085
macromolecule localizationGO:00330367710.085
cell cycle processGO:00224024820.084
positive regulation of macromolecule metabolic processGO:00106041490.083
regulation of primary metabolic processGO:00800902920.082
Yeast
ovipositionGO:00189913640.081
gene silencingGO:00164581430.080
positive regulation of developmental growthGO:00486393540.080
regulation of macromolecule metabolic processGO:00602554210.080
behaviorGO:00076105270.080
cell motilityGO:00488703130.079
regulation of multicellular organism growthGO:00400143730.078
response to woundingGO:000961140.075
lipid localizationGO:00108765730.075
er nucleus signaling pathwayGO:0006984660.074
neuron developmentGO:00486661990.074
organelle organizationGO:00069967830.071
membrane organizationGO:00610241350.071
negative regulation of multicellular organismal processGO:00512412360.070
protein localization to endoplasmic reticulumGO:007097220.069
regulation of post embryonic developmentGO:00485802600.068
establishment of organelle localizationGO:00516561230.067
lipid storageGO:00199155650.067
negative regulation of post embryonic developmentGO:00485812080.064
single organism membrane fusionGO:0044801130.063
multi organism behaviorGO:00517053890.062
negative regulation of developmental processGO:00510932270.059
multi multicellular organism processGO:00447063900.059
cell proliferationGO:00082831160.058
chromosome segregationGO:00070591800.057
Human Yeast
cellular macromolecule biosynthetic processGO:00346452470.057
Yeast
neuron differentiationGO:00301822170.057
hermaphrodite genitalia developmentGO:00400357340.057
macromolecule modificationGO:00434122180.057
nucleic acid metabolic processGO:00903042990.056
protein complex subunit organizationGO:00718222800.056
regulation of signal transductionGO:00099661350.056
Human
phagocytosisGO:00069091150.056
multi organism reproductive behaviorGO:00447053870.056
negative regulation of macromolecule metabolic processGO:00106052290.055
sensory organ morphogenesisGO:009059620.054
organelle assemblyGO:00709252140.054
mitotic cell cycle processGO:19030471940.054
regulation of response to stimulusGO:00485832430.053
Human
inductive cell migrationGO:00400391450.053
protein complex assemblyGO:00064611860.052
positive regulation of multicellular organismal processGO:00512404170.051
muscle tissue developmentGO:006053710.051
heterocycle biosynthetic processGO:00181301870.051
cellular biosynthetic processGO:00442493150.050
Yeast
regulation of cellular macromolecule biosynthetic processGO:20001121880.050
Yeast
localization of cellGO:00516743130.050
proteolysisGO:0006508610.049
Yeast
sex differentiationGO:00075489090.049
actin filament based processGO:00300291910.048
organic substance catabolic processGO:19015752940.048
Yeast
regulation of rna metabolic processGO:00512521730.048
regulation of cellular component organizationGO:00511282480.048
Yeast
cell divisionGO:00513012620.048
macromolecular complex assemblyGO:00650031930.047
positive regulation of cellular processGO:00485223320.047
Human
positive regulation of molecular functionGO:0044093610.047
post embryonic organ developmentGO:00485693360.046
phosphate containing compound metabolic processGO:00067962320.046
Yeast
regulation of gene expressionGO:00104683660.045
oxidation reduction processGO:0055114590.045
neuromuscular junction developmentGO:000752820.045
regulation of localizationGO:00328791940.044
gene expressionGO:00104674120.044
aromatic compound biosynthetic processGO:00194381920.044
organelle disassemblyGO:190300820.044
protein localizationGO:00081042050.042
mitotic nuclear envelope reassemblyGO:000708430.042
biosynthetic processGO:00090583230.042
Yeast
regulation of protein metabolic processGO:0051246810.041
Yeast
cellular catabolic processGO:00442481990.041
Yeast
cell surface receptor signaling pathwayGO:00071661490.038
Human
memoryGO:000761330.038
regulation of cell migrationGO:0030334550.037
phagocytosis engulfmentGO:0006911980.037
response to external stimulusGO:00096052890.036
single organism catabolic processGO:00447121290.036
Yeast
reproductive system developmentGO:00614588500.036
establishment of mitotic spindle orientationGO:0000132280.035
cellular protein complex assemblyGO:00436231780.035
regulation of metabolic processGO:00192224780.035
regulation of mitotic cell cycleGO:0007346760.035
Yeast
reproductive behaviorGO:00190983870.035
posttranscriptional gene silencingGO:00164411430.035
apoptotic cell clearanceGO:00432771110.035
actin cytoskeleton organizationGO:00300361840.034
taxisGO:00423301280.034
regulation of biosynthetic processGO:00098891890.033
Yeast
positive regulation of metabolic processGO:00098931870.033
neuron projection developmentGO:00311751870.033
regulation of cell motilityGO:2000145570.033
regulation of organelle organizationGO:00330431640.033
Yeast
positive regulation of nitrogen compound metabolic processGO:00511731340.032
regulation of cell cycle processGO:00105641450.031
Yeast
positive regulation of protein metabolic processGO:0051247450.031
regulation of cytoskeleton organizationGO:0051493410.031
multicellular organismal reproductive behaviorGO:00330573840.030
secretionGO:00469031470.030
cellular component morphogenesisGO:00329893180.030
single organism membrane organizationGO:0044802350.030
negative regulation of gene expressionGO:00106292170.030
cell part morphogenesisGO:00329901520.030
macromolecule catabolic processGO:00090572020.030
Yeast
negative regulation of cellular component organizationGO:0051129330.030
Yeast
transmembrane transportGO:00550851100.030
regulation of transcription dna templatedGO:00063551640.030
chromatin assembly or disassemblyGO:000633310.030
protein catabolic processGO:00301631620.030
Yeast
regulation of signalingGO:00230511720.029
Human
molting cycleGO:00423032810.029
response to heatGO:0009408500.029
head developmentGO:006032210.029
embryonic body morphogenesisGO:0010172490.028
cell morphogenesis involved in differentiationGO:00009041120.028
cellular nitrogen compound biosynthetic processGO:00442711920.028
negative regulation of gene expression epigeneticGO:004581420.028
response to temperature stimulusGO:0009266660.028
organ morphogenesisGO:0009887670.028
rna biosynthetic processGO:00327741690.028
response to abiotic stimulusGO:00096281520.027
nuclear migrationGO:0007097540.027
phosphorus metabolic processGO:00067932320.027
Yeast
nucleobase containing compound metabolic processGO:00061394060.027
regulation of cell proliferationGO:00421271050.027
establishment of protein localization to membraneGO:009015030.026
positive regulation of phosphate metabolic processGO:0045937560.026
regenerationGO:003109940.026
pattern specification processGO:0007389590.026
regulation of nucleic acid templated transcriptionGO:19035061650.025
neuroblast divisionGO:005505790.025
negative regulation of cell morphogenesis involved in differentiationGO:001077120.025
macromolecule biosynthetic processGO:00090592500.025
Yeast
regulation of rna biosynthetic processGO:20011411650.025
oxoacid metabolic processGO:0043436470.025
gene silencing by rnaGO:00310471430.025
phosphorylationGO:00163101160.025
cellular macromolecular complex assemblyGO:00346221840.024
maintenance of protein locationGO:0045185150.024
synaptic vesicle localizationGO:0097479220.023
cellular response to inorganic substanceGO:007124130.023
protein phosphorylationGO:0006468850.023
golgi vesicle transportGO:004819330.023
collagen and cuticulin based cuticle developmentGO:0040002990.023
molting cycle collagen and cuticulin based cuticleGO:00189962810.023
nucleobase containing compound biosynthetic processGO:00346541840.023
negative regulation of biosynthetic processGO:0009890650.023
epithelial tube morphogenesisGO:006056210.023
single organism carbohydrate metabolic processGO:0044723290.022
nucleic acid templated transcriptionGO:00976591690.022
transcription dna templatedGO:00063511680.022
adult behaviorGO:003053430.022
positive regulation of post embryonic developmentGO:0048582540.021
rna processingGO:0006396340.021
endomembrane system organizationGO:0010256220.021
signal transduction by phosphorylationGO:0023014310.021
neuron projection morphogenesisGO:00488121140.021
positive regulation of phosphorus metabolic processGO:0010562560.020
mitotic spindle organizationGO:0007052810.020
adult locomotory behaviorGO:000834410.020
regulation of phosphate metabolic processGO:0019220810.020
regulation of meiotic cell cycleGO:00514451360.020
carbohydrate derivative metabolic processGO:19011351410.020
single organism transportGO:00447654470.020
regulation of locomotionGO:00400121610.020
regulation of cellular biosynthetic processGO:00313261890.020
Yeast
cellular response to chemical stimulusGO:00708871290.019
negative regulation of signal transductionGO:0009968600.019
negative regulation of cellular protein metabolic processGO:0032269270.019
Yeast
regulation of cell communicationGO:00106461760.019
Human
posttranscriptional gene silencing by rnaGO:00351941430.019
establishment of spindle localizationGO:0051293510.019
establishment of mitotic spindle localizationGO:0040001410.019
cell fate commitmentGO:00451651390.019
regulation of nucleobase containing compound metabolic processGO:00192192220.019
ras protein signal transductionGO:0007265310.019
protein targeting to mitochondrionGO:000662620.019
cell cell signalingGO:00072671180.018
regulation of transcription from rna polymerase ii promoterGO:00063571450.018
regulation of apoptotic processGO:0042981360.018
Human
dna metabolic processGO:0006259740.018
skeletal muscle organ developmentGO:006053830.018
negative regulation of signalingGO:0023057610.018
regulation of catalytic activityGO:0050790780.018
spindle localizationGO:0051653510.018
cellular response to organic substanceGO:00713101190.018
er associated ubiquitin dependent protein catabolic processGO:003043360.018
establishment of vesicle localizationGO:0051650230.018
cellular amine metabolic processGO:0044106150.018
establishment of synaptic vesicle localizationGO:0097480210.018
positive regulation of vulval developmentGO:0040026520.018
myofibril assemblyGO:00302391540.017
organic cyclic compound biosynthetic processGO:19013621950.017
regulation of nitrogen compound metabolic processGO:00511712220.017
regulation of molecular functionGO:0065009890.017
regulation of phosphorus metabolic processGO:0051174810.017
cuticle developmentGO:00423351000.017
engulfment of apoptotic cellGO:0043652940.017
cellular protein localizationGO:0034613750.017
tissue developmentGO:00098881120.017
membrane invaginationGO:0010324980.017
carbohydrate metabolic processGO:0005975340.017
chromatin remodelingGO:000633820.017
positive regulation of nematode larval developmentGO:0061063540.017
anatomical structure formation involved in morphogenesisGO:00486462500.016
cellular localizationGO:00516413600.016
establishment or maintenance of cell polarityGO:0007163630.016
actin filament organizationGO:0007015210.016
muscle structure developmentGO:00610611910.016
cell type specific apoptotic processGO:009728540.016
cation transportGO:0006812780.016
organic substance biosynthetic processGO:19015763230.016
Yeast
cell morphogenesis involved in neuron differentiationGO:00486671110.016
small molecule metabolic processGO:00442811860.016
regulation of synapse assemblyGO:005196320.016
axon guidanceGO:0007411820.016
nucleus organizationGO:0006997380.016
organic substance transportGO:00717021130.016
posttranscriptional regulation of gene expressionGO:00106081660.015
rna metabolic processGO:00160702280.015
organophosphate metabolic processGO:00196371250.015
regulation of multi organism processGO:0043900690.015
small gtpase mediated signal transductionGO:0007264320.015
eating behaviorGO:0042755590.015
cell recognitionGO:0008037850.015
ribonucleoprotein complex assemblyGO:002261840.015
positive regulation of nucleic acid templated transcriptionGO:19035081020.015
male sex differentiationGO:0046661860.015
muscle contractionGO:0006936430.015
negative regulation of metabolic processGO:00098922400.015
membrane fusionGO:0061025160.015
positive regulation of transcription dna templatedGO:00458931020.015
positive regulation of protein modification processGO:0031401290.014
regulation of protein stabilityGO:003164730.014
regulation of protein ubiquitinationGO:003139630.014
negative regulation of neurogenesisGO:005076840.014
cellular component assembly involved in morphogenesisGO:00109271830.014
regulation of sequence specific dna binding transcription factor activityGO:005109030.014
regulation of macromolecule biosynthetic processGO:00105561890.014
Yeast
synaptic growth at neuromuscular junctionGO:005112410.014
cellular macromolecule localizationGO:0070727750.014
sterol transportGO:001591840.014
organelle fusionGO:004828480.014
mapk cascadeGO:0000165310.014
regulation of cellular ketone metabolic processGO:001056530.014
nucleus localizationGO:0051647550.014
anion transportGO:0006820300.014
neuronal stem cell divisionGO:003644590.014
protein modification by small protein conjugation or removalGO:0070647400.014
spindle assemblyGO:005122580.013
negative regulation of cell communicationGO:0010648610.013
microtubule cytoskeleton organization involved in mitosisGO:1902850120.013
oocyte axis specificationGO:000730920.013
maintenance of protein location in cellGO:0032507120.013
regulation of cellular amine metabolic processGO:003323800.013
asymmetric neuroblast divisionGO:005505980.013
single organism biosynthetic processGO:0044711910.013
autophagyGO:0006914290.013
regulation of cell cycleGO:00517261940.013
Yeast
positive regulation of gene expressionGO:00106281120.013
intracellular signal transductionGO:0035556960.013
regulation of intracellular signal transductionGO:1902531770.013
positive regulation of catalytic activityGO:0043085590.013
defense response to other organismGO:00985421000.013
male anatomical structure morphogenesisGO:0090598780.013
rna interferenceGO:00162461370.013
axonal fasciculationGO:0007413790.013
negative regulation of cell cycleGO:0045786530.012
Yeast
positive regulation of neurogenesisGO:005076940.012
carboxylic acid metabolic processGO:0019752340.012
vesicle localizationGO:0051648240.012
positive regulation of protein transportGO:005122240.012
nucleic acid transportGO:005065730.012
cell projection organizationGO:00300302310.012
response to organic substanceGO:00100331310.012
regulation of behaviorGO:0050795970.012
single organism behaviorGO:0044708830.012
nuclear envelope reassemblyGO:003146840.012
protein localization to mitochondrionGO:007058520.012
immune responseGO:00069551920.012
feeding behaviorGO:0007631700.012
negative regulation of cellular metabolic processGO:0031324950.012
Yeast
organonitrogen compound metabolic processGO:19015641510.012
hatchingGO:0035188480.012
negative regulation of protein metabolic processGO:0051248270.012
Yeast
positive regulation of cell communicationGO:0010647690.012
Human
regulation of synaptic growth at neuromuscular junctionGO:000858210.012
regulation of ras protein signal transductionGO:0046578410.012
myosin filament organizationGO:00310331380.012
embryonic morphogenesisGO:00485981520.012
cell projection morphogenesisGO:00488581480.012
muscle cell differentiationGO:00426921710.012
regulation of response to woundingGO:190303410.012
regulation of small gtpase mediated signal transductionGO:0051056410.012
organic acid metabolic processGO:0006082470.012
negative regulation of response to stimulusGO:0048585730.012
regulation of cell deathGO:0010941650.011
Human
spindle assembly involved in mitosisGO:009030760.011
regulation of programmed cell deathGO:0043067500.011
Human
positive regulation of catabolic processGO:0009896380.011
striated muscle cell developmentGO:00550021570.011
regulation of protein targetingGO:190353330.011
regulation of cellular metabolic processGO:00313233050.011
Yeast
striated muscle cell differentiationGO:00511461580.011
regulation of cell differentiationGO:0045595810.011
purine nucleoside monophosphate metabolic processGO:0009126430.011
neurological system processGO:0050877530.011
mitotic cell cycle phase transitionGO:0044772130.011
Yeast
positive regulation of purine nucleotide metabolic processGO:1900544280.011
negative regulation of nitrogen compound metabolic processGO:0051172630.011
positive regulation of signal transductionGO:0009967400.011
Human
positive regulation of cellular catabolic processGO:0031331350.011
chemotaxisGO:00069351200.011
regulation of lipid metabolic processGO:001921640.011
regulation of apoptotic signaling pathwayGO:200123310.011
Human
pronuclear migrationGO:0035046510.011
synaptic transmissionGO:00072681060.011
myosin filament assemblyGO:00310341380.011
short term memoryGO:000761420.011
endosomal transportGO:0016197260.010
g protein coupled receptor signaling pathwayGO:0007186460.010
mitochondrion organizationGO:0007005200.010
cell projection assemblyGO:0030031350.010
purine ribonucleotide metabolic processGO:0009150950.010
response to chemicalGO:00422213560.010
muscle cell developmentGO:00550011580.010
cellular protein catabolic processGO:0044257370.010
Yeast

paa-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.031
lipodystrophyDOID:81100.027
integumentary system diseaseDOID:1600.027
familial partial lipodystrophyDOID:005044000.027
skin diseaseDOID:3700.027
congenital muscular dystrophyDOID:005055700.023
musculoskeletal system diseaseDOID:1700.023
muscular dystrophyDOID:988400.023
muscular diseaseDOID:008000000.023
muscle tissue diseaseDOID:6600.023
myopathyDOID:42300.023
progeriaDOID:391100.020
nervous system diseaseDOID:86300.018
cardiovascular system diseaseDOID:128700.010
cardiomyopathyDOID:005070000.010
heart diseaseDOID:11400.010