Caenorhabditis elegans

92 known processes

zen-4 (CELE_M03D4.1)

Protein ZEN-4

zen-4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
gonad developmentGO:00084068400.896
embryo development ending in birth or egg hatchingGO:000979229920.886
sexual reproductionGO:00199535460.865
sex differentiationGO:00075489090.864
developmental process involved in reproductionGO:000300611650.848
reproductive system developmentGO:00614588500.813
meiotic cell cycle processGO:19030461700.775
hermaphrodite genitalia developmentGO:00400357340.740
development of primary sexual characteristicsGO:00451378400.695
gamete generationGO:00072764610.650
positive regulation of cellular processGO:00485223320.644
Human Fly
organ developmentGO:004851311020.638
multicellular organismal reproductive processGO:00486098150.621
multicellular organism reproductionGO:00325048190.608
vulval developmentGO:00400253330.598
regulation of vulval developmentGO:00400282480.593
regulation of nematode larval developmentGO:00610622600.587
genitalia developmentGO:00488067410.558
meiotic cell cycleGO:00513213350.549
cellular process involved in reproduction in multicellular organismGO:00224123510.512
positive regulation of vulval developmentGO:0040026520.503
single organism reproductive processGO:004470211960.502
post embryonic developmentGO:000979121520.499
post embryonic organ developmentGO:00485693360.494
embryo developmentGO:000979030520.483
negative regulation of vulval developmentGO:00400272060.468
catabolic processGO:00090563180.441
Human
germ cell developmentGO:00072813510.433
meiotic chromosome segregationGO:00451321390.430
Fly
cellular catabolic processGO:00442481990.414
Human
cell cycle processGO:00224024820.388
negative regulation of cellular processGO:00485232390.374
regulation of developmental processGO:00507936840.369
mitotic nuclear divisionGO:0007067890.345
response to chemicalGO:00422213560.341
cell fate commitmentGO:00451651390.339
Fly
organic substance catabolic processGO:19015752940.330
Human
reproductive structure developmentGO:00486088500.327
positive regulation of nematode larval developmentGO:0061063540.307
growthGO:00400075620.292
sister chromatid segregationGO:0000819460.290
multicellular organismal reproductive behaviorGO:00330573840.289
regulation of multicellular organismal processGO:00512397260.288
organelle fissionGO:00482853630.266
chromosome organization involved in meiosisGO:0070192250.255
nucleobase containing compound metabolic processGO:00061394060.250
Human
body morphogenesisGO:00101716200.247
negative regulation of biological processGO:00485195670.241
ovipositionGO:00189913640.235
locomotionGO:004001116340.234
negative regulation of nematode larval developmentGO:00610642080.232
negative regulation of post embryonic developmentGO:00485812080.223
regulation of meiotic cell cycleGO:00514451360.223
multi organism reproductive processGO:00447038670.219
positive regulation of developmental processGO:00510944080.216
protein catabolic processGO:00301631620.214
chromosome organizationGO:00512761040.212
chromosome segregationGO:00070591800.212
Fly
cell divisionGO:00513012620.211
regulation of multicellular organismal developmentGO:20000263170.211
regulation of macromolecule metabolic processGO:00602554210.198
oogenesisGO:00484772290.197
cell developmentGO:00484686960.196
regulation of primary metabolic processGO:00800902920.193
spindle organizationGO:0007051920.192
single organism catabolic processGO:00447121290.191
Human
regulation of post embryonic developmentGO:00485802600.191
meiotic nuclear divisionGO:00071263000.187
female gamete generationGO:00072922540.186
regulation of mitotic cell cycleGO:0007346760.186
macromolecule biosynthetic processGO:00090592500.184
apoptotic processGO:00069154780.182
negative regulation of multicellular organismal processGO:00512412360.179
negative regulation of developmental processGO:00510932270.169
cellular protein catabolic processGO:0044257370.165
positive regulation of multicellular organismal processGO:00512404170.164
macromolecule catabolic processGO:00090572020.159
multi multicellular organism processGO:00447063900.154
neurogenesisGO:00220082360.150
Fly
regulation of transcription dna templatedGO:00063551640.140
multi organism reproductive behaviorGO:00447053870.140
cellular macromolecule biosynthetic processGO:00346452470.139
purine nucleotide catabolic processGO:0006195750.137
Human
cell proliferationGO:00082831160.137
regulation of nucleobase containing compound metabolic processGO:00192192220.134
mitotic cell cycle processGO:19030471940.132
localization of cellGO:00516743130.130
single organism signalingGO:00447004010.129
Fly
regulation of cellular metabolic processGO:00313233050.129
biosynthetic processGO:00090583230.126
organelle organizationGO:00069967830.125
cellular nitrogen compound catabolic processGO:00442701190.123
Human
regulation of response to stimulusGO:00485832430.120
Fly
pattern specification processGO:0007389590.118
protein metabolic processGO:00195384220.118
macromolecule modificationGO:00434122180.118
meiosis iGO:0007127190.117
regulation of multicellular organism growthGO:00400143730.116
regulation of growthGO:00400084090.113
macromolecular complex subunit organizationGO:00439333200.111
ribonucleotide catabolic processGO:0009261750.111
Human
positive regulation of post embryonic developmentGO:0048582540.110
multicellular organism growthGO:00352643850.107
nucleoside catabolic processGO:0009164780.106
Human
nucleoside triphosphate metabolic processGO:0009141870.105
Human
modification dependent protein catabolic processGO:0019941320.104
regulation of gene expressionGO:00104683660.101
regulation of cell cycleGO:00517261940.100
regulation of signalingGO:00230511720.100
Fly
embryonic morphogenesisGO:00485981520.099
proteolysis involved in cellular protein catabolic processGO:0051603320.099
response to external stimulusGO:00096052890.098
cell migrationGO:00164773060.098
organonitrogen compound catabolic processGO:1901565900.097
Human
glycosyl compound metabolic processGO:19016571000.096
Human
regulation of rna metabolic processGO:00512521730.096
ubiquitin dependent protein catabolic processGO:0006511320.096
cellular biosynthetic processGO:00442493150.096
organic cyclic compound biosynthetic processGO:19013621950.094
regulation of nucleic acid templated transcriptionGO:19035061650.094
regulation of developmental growthGO:00486383890.092
attachment of spindle microtubules to kinetochoreGO:000860880.092
transmembrane transportGO:00550851100.091
regulation of metabolic processGO:00192224780.090
establishment of localizationGO:005123411710.090
positive regulation of multicellular organism growthGO:00400183520.089
signalingGO:00230524010.089
Fly
molting cycleGO:00423032810.088
multi organism behaviorGO:00517053890.088
reproductive behaviorGO:00190983870.087
mitotic sister chromatid segregationGO:0000070380.085
cellular protein metabolic processGO:00442672790.084
purine ribonucleotide catabolic processGO:0009154750.083
Human
negative regulation of metabolic processGO:00098922400.083
agingGO:00075688120.080
nucleic acid metabolic processGO:00903042990.080
behaviorGO:00076105270.080
dna metabolic processGO:0006259740.080
regulation of biological qualityGO:00650087410.080
Fly
cell cycleGO:00070495260.080
spindle assemblyGO:005122580.079
phosphorus metabolic processGO:00067932320.078
Human
tissue developmentGO:00098881120.078
purine nucleoside catabolic processGO:0006152750.077
Human
proteolysisGO:0006508610.077
regulation of cellular macromolecule biosynthetic processGO:20001121880.077
aromatic compound biosynthetic processGO:00194381920.077
glycosyl compound catabolic processGO:1901658790.076
Human
gene expressionGO:00104674120.075
transcription dna templatedGO:00063511680.075
regulation of nuclear divisionGO:00517831150.074
developmental growthGO:00485894120.073
ribonucleoside monophosphate metabolic processGO:0009161450.073
Human
aromatic compound catabolic processGO:00194391160.072
Human
nucleoside phosphate catabolic processGO:1901292770.072
Human
synaptonemal complex assemblyGO:000713060.071
establishment of localization in cellGO:00516493180.071
nucleoside metabolic processGO:0009116990.071
Human
nucleic acid templated transcriptionGO:00976591690.069
cell deathGO:00082195470.069
regulation of rna biosynthetic processGO:20011411650.069
molting cycle collagen and cuticulin based cuticleGO:00189962810.068
defense responseGO:00069522960.067
modification dependent macromolecule catabolic processGO:0043632320.066
tube developmentGO:00352951260.066
rna biosynthetic processGO:00327741690.065
organonitrogen compound metabolic processGO:19015641510.064
Human
protein modification processGO:00362112070.064
organ morphogenesisGO:0009887670.063
regulation of cell proliferationGO:00421271050.063
regulation of macromolecule biosynthetic processGO:00105561890.062
cytokinesisGO:0000910800.061
purine ribonucleoside metabolic processGO:0046128920.060
Human
positive regulation of chromosome segregationGO:005198410.060
digestive tract developmentGO:00485651220.059
microtubule based processGO:00070171820.056
single organism biosynthetic processGO:0044711910.056
nucleoside triphosphate catabolic processGO:0009143720.055
Human
regulation of cellular biosynthetic processGO:00313261890.055
cellular macromolecular complex assemblyGO:00346221840.053
receptor mediated endocytosisGO:00068987150.053
negative regulation of gene expressionGO:00106292170.053
single organism localizationGO:19025785180.052
Zebrafish Fly
fertilizationGO:0009566630.052
positive regulation of nucleobase containing compound metabolic processGO:00459351340.050
positive regulation of cellular protein catabolic processGO:190336430.050
positive regulation of mitotic sister chromatid separationGO:190197010.050
microtubule polymerization or depolymerizationGO:0031109220.049
small molecule metabolic processGO:00442811860.049
Human
maintenance of locationGO:00512355800.049
Fly
purine ribonucleoside triphosphate metabolic processGO:0009205870.048
Human
ribonucleoside catabolic processGO:0042454770.048
Human
positive regulation of developmental growthGO:00486393540.048
cellular nitrogen compound biosynthetic processGO:00442711920.048
ribonucleoside triphosphate catabolic processGO:0009203720.047
Human
cellular response to stressGO:00335541620.047
organic cyclic compound catabolic processGO:19013611190.047
Human
programmed cell deathGO:00125015000.047
lipid localizationGO:00108765730.046
single organism transportGO:00447654470.046
Zebrafish Fly
macromolecule localizationGO:00330367710.044
Fly
positive regulation of cell cycleGO:0045787550.044
Human
cell motilityGO:00488703130.044
oocyte differentiationGO:0009994450.044
proteasomal protein catabolic processGO:0010498200.043
nucleobase containing compound catabolic processGO:00346551140.043
Human
cell projection organizationGO:00300302310.043
cell surface receptor signaling pathwayGO:00071661490.042
Fly
inductive cell migrationGO:00400391450.041
head developmentGO:006032210.041
protein complex subunit organizationGO:00718222800.041
nucleobase containing compound biosynthetic processGO:00346541840.041
multicellular organismal agingGO:00102598120.041
cellular macromolecule catabolic processGO:0044265730.040
lipid storageGO:00199155650.040
cellular component morphogenesisGO:00329893180.039
ribonucleoside triphosphate metabolic processGO:0009199870.039
Human
deathGO:00162655470.039
protein complex assemblyGO:00064611860.039
mitotic spindle organizationGO:0007052810.039
rna metabolic processGO:00160702280.038
intracellular signal transductionGO:0035556960.038
small gtpase mediated signal transductionGO:0007264320.038
regulation of meiosisGO:0040020940.038
purine nucleoside triphosphate catabolic processGO:0009146720.037
Human
purine containing compound catabolic processGO:0072523750.037
Human
organic substance biosynthetic processGO:19015763230.037
heterocycle catabolic processGO:00467001190.037
Human
negative regulation of signal transductionGO:0009968600.037
posttranscriptional regulation of gene expressionGO:00106081660.037
regulation of phosphorus metabolic processGO:0051174810.037
chromatin remodelingGO:000633820.036
cellular protein modification processGO:00064642070.036
positive regulation of proteasomal protein catabolic processGO:190180010.036
regulation of organelle organizationGO:00330431640.035
Fly
epithelium developmentGO:0060429680.035
nervous system developmentGO:00073992530.035
Fly
negative regulation of macromolecule metabolic processGO:00106052290.035
taxisGO:00423301280.035
signal transductionGO:00071653170.034
Fly
nucleoside phosphate metabolic processGO:00067531080.033
Human
vesicle mediated transportGO:00161928520.033
cellular component movementGO:00069283880.033
positive regulation of growthGO:00459273690.033
phosphate containing compound metabolic processGO:00067962320.032
Human
regulation of molecular functionGO:0065009890.032
purine ribonucleoside catabolic processGO:0046130750.032
Human
neuron projection developmentGO:00311751870.032
positive regulation of chromosome organizationGO:200125220.032
carbohydrate derivative catabolic processGO:1901136820.031
Human
regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243450.030
regulation of cell communicationGO:00106461760.030
Fly
cellular response to chemical stimulusGO:00708871290.030
purine nucleoside triphosphate metabolic processGO:0009144870.030
Human
regulation of mitosisGO:0007088180.029
posttranscriptional gene silencingGO:00164411430.029
response to abiotic stimulusGO:00096281520.029
transportGO:000681010930.029
Zebrafish Fly
negative regulation of response to stimulusGO:0048585730.029
single organism organelle organizationGO:19025895010.028
male gamete generationGO:0048232410.028
regulation of cell differentiationGO:0045595810.028
organophosphate catabolic processGO:0046434810.028
Human
chromatin modificationGO:0016568320.028
polar body extrusion after meiotic divisionsGO:0040038140.028
purine nucleoside monophosphate metabolic processGO:0009126430.028
Human
determination of adult lifespanGO:00083408120.028
negative regulation of signalingGO:0023057610.028
negative regulation of cellular protein metabolic processGO:0032269270.028
positive regulation of cellular metabolic processGO:00313251780.028
microtubule anchoringGO:003445380.028
dna conformation changeGO:0071103110.028
negative regulation of nucleic acid templated transcriptionGO:1903507530.028
microtubule depolymerizationGO:0007019100.027
regulation of nitrogen compound metabolic processGO:00511712220.027
digestive system developmentGO:00551231220.027
regulation of cell divisionGO:00513021420.027
positive regulation of transcription dna templatedGO:00458931020.026
regulation of locomotionGO:00400121610.026
system processGO:00030081360.026
response to other organismGO:00517071010.026
cellular localizationGO:00516413600.026
positive regulation of macromolecule biosynthetic processGO:00105571090.026
positive regulation of nitrogen compound metabolic processGO:00511731340.026
endocytosisGO:00068978190.026
actin filament based processGO:00300291910.026
muscle structure developmentGO:00610611910.026
Fly
cellular protein localizationGO:0034613750.026
Fly
nucleotide catabolic processGO:0009166770.026
Human
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161200.026
cytoskeleton dependent cytokinesisGO:0061640350.026
dna repairGO:0006281230.025
regulation of phosphate metabolic processGO:0019220810.025
regulation of biosynthetic processGO:00098891890.025
regulation of cellular component organizationGO:00511282480.025
Fly
positive regulation of proteolysis involved in cellular protein catabolic processGO:190305210.024
carbohydrate derivative metabolic processGO:19011351410.024
Human
neuron developmentGO:00486661990.024
collagen and cuticulin based cuticle developmentGO:0040002990.024
gene silencing by rnaGO:00310471430.024
ribonucleoside metabolic processGO:0009119980.024
Human
positive regulation of phosphorus metabolic processGO:0010562560.024
oocyte developmentGO:0048599440.023
heterocycle biosynthetic processGO:00181301870.023
synapsisGO:0007129100.023
rna interferenceGO:00162461370.023
generation of neuronsGO:00486992350.023
negative regulation of protein metabolic processGO:0051248270.023
purine ribonucleoside triphosphate catabolic processGO:0009207720.023
Human
tube morphogenesisGO:0035239790.023
amine metabolic processGO:0009308150.023
cellular amine metabolic processGO:0044106150.022
cytoskeleton organizationGO:00070103390.022
organelle assemblyGO:00709252140.022
dna recombinationGO:0006310190.022
transcription from rna polymerase ii promoterGO:00063661490.022
regulation of signal transductionGO:00099661350.022
Fly
mitotic metaphase plate congressionGO:000708050.022
negative regulation of cellular component organizationGO:0051129330.022
gene silencingGO:00164581430.022
ribose phosphate metabolic processGO:0019693990.022
Human
posttranscriptional gene silencing by rnaGO:00351941430.022
positive regulation of catalytic activityGO:0043085590.021
histone modificationGO:0016570300.021
protein phosphorylationGO:0006468850.021
positive regulation of phosphate metabolic processGO:0045937560.021
female meiotic divisionGO:0007143170.021
nucleoside monophosphate metabolic processGO:0009123460.021
Human
regulation of localizationGO:00328791940.020
Fly
pronuclear migrationGO:0035046510.020
chemotaxisGO:00069351200.020
metaphase anaphase transition of mitotic cell cycleGO:0007091100.020
phosphorylationGO:00163101160.020
negative regulation of cell cycleGO:0045786530.020
muscle system processGO:0003012430.019
actomyosin structure organizationGO:00310321540.019
muscle contractionGO:0006936430.019
regulation of cellular ketone metabolic processGO:001056530.019
mitotic sister chromatid separationGO:0051306130.019
oxoacid metabolic processGO:0043436470.019
response to external biotic stimulusGO:00432071010.019
kinetochore organizationGO:005138370.018
regulation of sister chromatid segregationGO:0033045160.018
regulation of cellular amine metabolic processGO:003323800.018
cellular protein complex assemblyGO:00436231780.018
negative regulation of nitrogen compound metabolic processGO:0051172630.018
metaphase anaphase transition of cell cycleGO:0044784150.018
regulation of intracellular signal transductionGO:1902531770.018
cellular component biogenesisGO:00440852970.017
response to endoplasmic reticulum stressGO:0034976710.017
ion transportGO:00068111130.017
positive regulation of cellular catabolic processGO:0031331350.017
covalent chromatin modificationGO:0016569300.017
dna packagingGO:000632370.017
peptidyl amino acid modificationGO:0018193580.017
cellular response to organic substanceGO:00713101190.017
axon guidanceGO:0007411820.017
establishment of organelle localizationGO:00516561230.017
chromatin organizationGO:0006325320.017
regulation of mitotic metaphase anaphase transitionGO:003007150.017
immune responseGO:00069551920.017
purine nucleoside metabolic processGO:0042278920.017
Human
defense response to other organismGO:00985421000.017
male sex differentiationGO:0046661860.016
neuron recognitionGO:0008038830.016
regulation of sequence specific dna binding transcription factor activityGO:005109030.016
establishment of chromosome localizationGO:0051303100.016
axon developmentGO:00615641630.016
spermatogenesisGO:0007283410.016
anatomical structure formation involved in morphogenesisGO:00486462500.016
neuron projection morphogenesisGO:00488121140.016
macromolecular complex assemblyGO:00650031930.015
regulation of apoptotic signaling pathwayGO:200123310.015
positive regulation of nucleic acid templated transcriptionGO:19035081020.015
regulation of protein stabilityGO:003164730.015
cell part morphogenesisGO:00329901520.015
regulation of cellular amino acid metabolic processGO:000652100.015
membrane organizationGO:00610241350.015
negative regulation of biosynthetic processGO:0009890650.015
epidermis developmentGO:0008544240.015
atp metabolic processGO:0046034420.015
Human
regulation of cell cycle processGO:00105641450.015
epithelial cell proliferationGO:005067310.015
metaphase plate congressionGO:005131050.015
peptidyl tyrosine phosphorylationGO:001810820.015
nucleus organizationGO:0006997380.015
lipid metabolic processGO:0006629770.015
regulation of mitotic cell cycle embryonicGO:000979450.015
ras protein signal transductionGO:0007265310.015
synaptonemal complex organizationGO:007019380.014
protein dna complex assemblyGO:006500470.014
regulation of epithelial cell differentiationGO:003085640.014
regulation of phosphorylationGO:0042325450.014
meiotic cytokinesisGO:0033206150.014
organic acid metabolic processGO:0006082470.014
cell cycle dna replicationGO:004478630.014
nucleus localizationGO:0051647550.014
meiosis iiGO:0007135160.014
chromatin assembly or disassemblyGO:000633310.014
ribonucleoprotein complex assemblyGO:002261840.014
regulation of protein serine threonine kinase activityGO:0071900180.014
regulation of catalytic activityGO:0050790780.014
endomembrane system organizationGO:0010256220.014
positive regulation of epithelial cell proliferationGO:005067910.014
neuron differentiationGO:00301822170.014
development of primary male sexual characteristicsGO:004654640.014
positive regulation of embryonic developmentGO:004001930.014
nucleobase containing small molecule metabolic processGO:00550861150.014
Human
regulation of lipid metabolic processGO:001921640.014
positive regulation of proteasomal ubiquitin dependent protein catabolic processGO:003243610.014
negative regulation of neurogenesisGO:005076840.014
regulation of mitotic sister chromatid segregationGO:0033047160.014
protein oligomerizationGO:005125940.013
positive regulation of meiotic cell cycleGO:0051446470.013
cellular component assemblyGO:00226072930.013
response to bacteriumGO:0009617860.013
meiotic chromosome separationGO:005130750.013
protein complex biogenesisGO:00702711860.013
reciprocal meiotic recombinationGO:0007131110.013
positive regulation of rna metabolic processGO:00512541030.013
response to biotic stimulusGO:00096071010.013
regulation of mitotic spindle organizationGO:006023630.013
cuticle developmentGO:00423351000.013
digestive tract morphogenesisGO:0048546760.013
carboxylic acid metabolic processGO:0019752340.013
regulation of microtubule cytoskeleton organizationGO:0070507210.013
Fly
cellular ketone metabolic processGO:0042180140.012
cellular protein complex disassemblyGO:0043624180.012
regulation of cellular protein metabolic processGO:0032268750.012
striated muscle cell differentiationGO:00511461580.012
phagocytosisGO:00069091150.012
positive regulation of gene expressionGO:00106281120.012
positive regulation of rna biosynthetic processGO:19026801020.012
organophosphate metabolic processGO:00196371250.012
Human
regulation of cellular response to oxidative stressGO:190040710.012
regulation of gene expression epigeneticGO:00400291630.012
mitotic spindle stabilizationGO:004314820.012
nematode male tail tip morphogenesisGO:0045138770.012
feeding behaviorGO:0007631700.012
muscle cell differentiationGO:00426921710.012
chromosome separationGO:0051304190.012
cellular response to abiotic stimulusGO:007121440.012
regulation of organ morphogenesisGO:200002740.012
mitotic cell cycle phase transitionGO:0044772130.011
cell cycle phase transitionGO:0044770190.011
negative regulation of cellular biosynthetic processGO:0031327650.011
purine containing compound metabolic processGO:0072521950.011
Human
negative regulation of macromolecule biosynthetic processGO:0010558650.011
internal peptidyl lysine acetylationGO:001839330.011
pharyngeal pumpingGO:0043050580.011
maintenance of protein location in cellGO:0032507120.011
Fly
axonal fasciculationGO:0007413790.011
mesoderm developmentGO:0007498270.011
secretionGO:00469031470.011
cell cycle g2 m phase transitionGO:004483910.011
negative regulation of mitotic cell cycleGO:0045930420.011
regulation of nucleocytoplasmic transportGO:004682230.011
Fly
negative regulation of cell communicationGO:0010648610.011
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.011
sensory organ morphogenesisGO:009059620.011
organelle localizationGO:00516401270.011
peptidyl lysine acetylationGO:001839430.011
nuclear envelope disassemblyGO:005108120.010
positive regulation of catabolic processGO:0009896380.010
cell morphogenesisGO:00009021630.010
cell type specific apoptotic processGO:009728540.010
g1 s transition of mitotic cell cycleGO:000008220.010
autophagyGO:0006914290.010
cellular response to dna damage stimulusGO:0006974410.010
actin filament bundle assemblyGO:005101730.010
macromolecular complex disassemblyGO:0032984200.010
positive regulation of signal transductionGO:0009967400.010
nucleoside monophosphate catabolic processGO:0009125280.010
Human
negative regulation of nucleobase containing compound metabolic processGO:0045934630.010

zen-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
disease of cellular proliferationDOID:1456600.016
cancerDOID:16200.016
nervous system diseaseDOID:86300.013