Caenorhabditis elegans

37 known processes

pde-4 (CELE_R153.1)

Protein PDE-4

pde-4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
g protein coupled receptor signaling pathwayGO:0007186460.762
negative regulation of vulval developmentGO:00400272060.543
muscle tissue developmentGO:006053710.528
response to chemicalGO:00422213560.499
post embryonic developmentGO:000979121520.499
embryo developmentGO:000979030520.495
cell developmentGO:00484686960.455
axon guidanceGO:0007411820.447
neuron projection guidanceGO:0097485820.420
multicellular organism reproductionGO:00325048190.387
regulation of developmental processGO:00507936840.380
locomotionGO:004001116340.370
multi organism reproductive behaviorGO:00447053870.362
signal transductionGO:00071653170.349
regulation of multicellular organismal processGO:00512397260.348
signalingGO:00230524010.338
embryo development ending in birth or egg hatchingGO:000979229920.327
single organism signalingGO:00447004010.295
negative regulation of biological processGO:00485195670.293
regulation of g protein coupled receptor protein signaling pathwayGO:000827740.286
regulation of multicellular organismal developmentGO:20000263170.278
establishment of localization in cellGO:00516493180.276
positive regulation of multicellular organismal processGO:00512404170.272
cellular component morphogenesisGO:00329893180.271
skeletal muscle organ developmentGO:006053830.269
positive regulation of nitrogen compound metabolic processGO:00511731340.258
neuron developmentGO:00486661990.257
programmed cell deathGO:00125015000.244
positive regulation of cellular metabolic processGO:00313251780.232
apoptotic processGO:00069154780.226
vesicle mediated transportGO:00161928520.226
regulation of macromolecule metabolic processGO:00602554210.224
multi organism reproductive processGO:00447038670.219
secretionGO:00469031470.218
regulation of biosynthetic processGO:00098891890.218
developmental process involved in reproductionGO:000300611650.213
neuron differentiationGO:00301822170.213
multi organism behaviorGO:00517053890.209
negative regulation of nematode larval developmentGO:00610642080.207
endocytosisGO:00068978190.207
single organism reproductive processGO:004470211960.206
cell migrationGO:00164773060.204
cellular localizationGO:00516413600.203
behaviorGO:00076105270.201
neuron projection developmentGO:00311751870.200
nucleobase containing compound metabolic processGO:00061394060.196
macromolecular complex subunit organizationGO:00439333200.195
positive regulation of macromolecule metabolic processGO:00106041490.191
neuron projection morphogenesisGO:00488121140.189
single organism localizationGO:19025785180.189
transportGO:000681010930.185
deathGO:00162655470.184
head developmentGO:006032210.184
neurogenesisGO:00220082360.183
regulation of nematode larval developmentGO:00610622600.181
multicellular organismal reproductive processGO:00486098150.181
single organism behaviorGO:0044708830.180
gamete generationGO:00072764610.178
negative regulation of developmental processGO:00510932270.176
regulation of gene expressionGO:00104683660.174
generation of neuronsGO:00486992350.171
single organism transportGO:00447654470.171
establishment of localizationGO:005123411710.171
ovipositionGO:00189913640.170
nucleobase containing compound biosynthetic processGO:00346541840.169
cellular component movementGO:00069283880.167
calcium ion transmembrane transportGO:0070588130.167
cellular process involved in reproduction in multicellular organismGO:00224123510.166
heterocycle biosynthetic processGO:00181301870.165
negative regulation of metabolic processGO:00098922400.164
cell part morphogenesisGO:00329901520.162
cellular response to organic substanceGO:00713101190.161
regulation of primary metabolic processGO:00800902920.160
sexual reproductionGO:00199535460.159
organ developmentGO:004851311020.159
cell projection organizationGO:00300302310.158
growthGO:00400075620.156
regulation of nucleocytoplasmic transportGO:004682230.156
transcription dna templatedGO:00063511680.155
gene expressionGO:00104674120.155
phosphate containing compound metabolic processGO:00067962320.155
regulation of multi organism processGO:0043900690.154
positive regulation of metabolic processGO:00098931870.153
organelle organizationGO:00069967830.150
multicellular organism growthGO:00352643850.150
reproductive behaviorGO:00190983870.149
response to woundingGO:000961140.146
negative regulation of macromolecule metabolic processGO:00106052290.146
organic cyclic compound biosynthetic processGO:19013621950.146
protein metabolic processGO:00195384220.145
multi multicellular organism processGO:00447063900.145
chemical homeostasisGO:0048878290.142
cellular biosynthetic processGO:00442493150.142
vulval developmentGO:00400253330.141
muscle structure developmentGO:00610611910.140
positive regulation of nucleobase containing compound metabolic processGO:00459351340.140
receptor mediated endocytosisGO:00068987150.139
secretion by cellGO:00329401380.139
phosphorus metabolic processGO:00067932320.138
regulation of metabolic processGO:00192224780.135
cell morphogenesis involved in differentiationGO:00009041120.135
multicellular organismal reproductive behaviorGO:00330573840.133
cell cycleGO:00070495260.133
positive regulation of locomotionGO:0040017420.133
regulation of oocyte maturationGO:190019370.133
cell deathGO:00082195470.132
positive regulation of cellular processGO:00485223320.131
negative regulation of cytosolic calcium ion concentrationGO:005148110.128
regulation of reproductive processGO:2000241660.127
positive regulation of nucleic acid templated transcriptionGO:19035081020.127
organic substance biosynthetic processGO:19015763230.127
cell projection morphogenesisGO:00488581480.126
positive regulation of developmental processGO:00510944080.125
axon developmentGO:00615641630.123
regulation of vulval developmentGO:00400282480.123
macromolecule biosynthetic processGO:00090592500.123
positive regulation of biosynthetic processGO:00098911090.123
cellular homeostasisGO:0019725220.120
multicellular organismal agingGO:00102598120.120
cellular response to chemical stimulusGO:00708871290.119
sarcomere organizationGO:0045214100.118
muscle cell developmentGO:00550011580.118
aromatic compound biosynthetic processGO:00194381920.118
regulation of post embryonic developmentGO:00485802600.118
cell motilityGO:00488703130.117
body morphogenesisGO:00101716200.116
agingGO:00075688120.116
cell surface receptor signaling pathwayGO:00071661490.116
regulation of nitrogen compound metabolic processGO:00511712220.115
cation transportGO:0006812780.113
single organism organelle organizationGO:19025895010.112
oogenesisGO:00484772290.112
adult behaviorGO:003053430.108
organonitrogen compound metabolic processGO:19015641510.108
muscle organ developmentGO:0007517260.108
striated muscle cell differentiationGO:00511461580.108
regulation of phosphate metabolic processGO:0019220810.108
purine nucleotide metabolic processGO:0006163950.106
cell morphogenesis involved in neuron differentiationGO:00486671110.106
cytosolic calcium ion homeostasisGO:005148020.105
macromolecule catabolic processGO:00090572020.104
negative regulation of post embryonic developmentGO:00485812080.104
response to organic substanceGO:00100331310.103
regulation of ovipositionGO:0046662430.102
regulation of growthGO:00400084090.102
immune responseGO:00069551920.101
regulation of cellular metabolic processGO:00313233050.100
chemotaxisGO:00069351200.099
regulation of phosphorus metabolic processGO:0051174810.098
organelle assemblyGO:00709252140.098
regulation of rna metabolic processGO:00512521730.097
anatomical structure formation involved in morphogenesisGO:00486462500.096
cell cycle processGO:00224024820.095
post embryonic organ developmentGO:00485693360.095
regulation of cellular macromolecule biosynthetic processGO:20001121880.095
regulation of cellular biosynthetic processGO:00313261890.094
cellular component assemblyGO:00226072930.093
macromolecule localizationGO:00330367710.093
cell type specific apoptotic processGO:009728540.092
regulation of cell developmentGO:0060284490.092
regulation of localizationGO:00328791940.092
regulation of transcription dna templatedGO:00063551640.091
neuroblast proliferationGO:000740590.091
nucleic acid metabolic processGO:00903042990.091
single organism cellular localizationGO:1902580720.090
regulation of cytoplasmic transportGO:190364930.090
cellular protein metabolic processGO:00442672790.089
posttranscriptional regulation of gene expressionGO:00106081660.089
nervous system developmentGO:00073992530.088
regulation of cellular catabolic processGO:0031329510.087
regulation of biological qualityGO:00650087410.085
homeostatic processGO:0042592510.084
extracellular structure organizationGO:004306270.083
memoryGO:000761330.083
meiotic cell cycleGO:00513213350.082
actin filament based processGO:00300291910.082
protein localizationGO:00081042050.082
regulation of catabolic processGO:0009894570.080
macromolecule modificationGO:00434122180.080
protein complex subunit organizationGO:00718222800.080
regulation of locomotionGO:00400121610.079
female gamete generationGO:00072922540.079
proteolysisGO:0006508610.079
developmental growthGO:00485894120.079
development of primary sexual characteristicsGO:00451378400.077
mating behaviorGO:0007617320.077
sensory organ morphogenesisGO:009059620.076
positive regulation of growthGO:00459273690.076
cellular protein modification processGO:00064642070.076
regulation of macromolecule biosynthetic processGO:00105561890.076
purine ribonucleotide metabolic processGO:0009150950.076
synaptic transmissionGO:00072681060.075
embryonic morphogenesisGO:00485981520.075
axonogenesisGO:00074091020.074
regulation of anatomical structure sizeGO:0090066460.074
meiotic nuclear divisionGO:00071263000.073
regulation of cell cycle processGO:00105641450.073
regulation of response to woundingGO:190303410.073
ion transmembrane transportGO:0034220910.073
regulation of signalingGO:00230511720.072
negative regulation of macromolecule biosynthetic processGO:0010558650.072
biosynthetic processGO:00090583230.072
regulation of developmental growthGO:00486383890.071
regulation of response to stimulusGO:00485832430.071
purine containing compound metabolic processGO:0072521950.069
regulation of signal transductionGO:00099661350.069
cytoskeleton organizationGO:00070103390.068
negative regulation of multicellular organismal processGO:00512412360.068
cell cell signalingGO:00072671180.067
germ cell developmentGO:00072813510.066
negative regulation of cellular processGO:00485232390.065
organophosphate metabolic processGO:00196371250.065
positive regulation of rna metabolic processGO:00512541030.065
negative regulation of gene expressionGO:00106292170.065
cation transmembrane transportGO:0098655590.065
regulation of cell cycleGO:00517261940.064
cellular protein localizationGO:0034613750.064
ion homeostasisGO:0050801210.063
epithelial tube morphogenesisGO:006056210.063
catabolic processGO:00090563180.062
ribonucleotide metabolic processGO:0009259990.062
cyclic nucleotide biosynthetic processGO:000919020.062
protein phosphorylationGO:0006468850.062
pattern specification processGO:0007389590.062
positive regulation of rna biosynthetic processGO:19026801020.061
neuromuscular junction developmentGO:000752820.061
macromolecular complex assemblyGO:00650031930.061
regulation of meiotic cell cycleGO:00514451360.060
maintenance of locationGO:00512355800.060
regulation of protein metabolic processGO:0051246810.060
stem cell proliferationGO:007208990.059
phosphorylationGO:00163101160.059
cellular macromolecule biosynthetic processGO:00346452470.059
regulation of synaptic transmissionGO:0050804340.059
lipid storageGO:00199155650.059
cellular component biogenesisGO:00440852970.058
taxisGO:00423301280.058
actin cytoskeleton organizationGO:00300361840.058
protein complex biogenesisGO:00702711860.058
muscle fiber developmentGO:004874720.057
regulation of transcription from rna polymerase ii promoterGO:00063571450.057
regulation of nucleic acid templated transcriptionGO:19035061650.056
myofibril assemblyGO:00302391540.056
dendrite developmentGO:0016358420.056
metal ion transportGO:0030001490.056
nucleobase containing small molecule metabolic processGO:00550861150.056
negative regulation of cellular metabolic processGO:0031324950.056
purine containing compound catabolic processGO:0072523750.055
localization of cellGO:00516743130.055
sex differentiationGO:00075489090.055
defense responseGO:00069522960.055
lipid localizationGO:00108765730.054
protein catabolic processGO:00301631620.053
carbohydrate derivative metabolic processGO:19011351410.053
response to nitrogen compoundGO:1901698250.052
cation homeostasisGO:0055080200.052
rna metabolic processGO:00160702280.052
regulation of molecular functionGO:0065009890.052
cellular macromolecule localizationGO:0070727750.052
positive regulation of cellular biosynthetic processGO:00313281090.052
learning or memoryGO:0007611270.051
negative regulation of response to stimulusGO:0048585730.051
positive regulation of developmental growthGO:00486393540.051
protein modification processGO:00362112070.050
nucleoside phosphate metabolic processGO:00067531080.050
dopamine receptor signaling pathwayGO:0007212110.049
transcription from rna polymerase ii promoterGO:00063661490.049
developmental maturationGO:0021700260.049
intracellular signal transductionGO:0035556960.048
locomotory behaviorGO:0007626400.048
inorganic cation transmembrane transportGO:0098662460.048
cellular catabolic processGO:00442481990.048
negative regulation of biosynthetic processGO:0009890650.047
regulation of cellular component organizationGO:00511282480.047
response to abiotic stimulusGO:00096281520.047
striated muscle cell developmentGO:00550021570.047
cognitionGO:0050890270.046
positive regulation of purine nucleotide metabolic processGO:1900544280.046
actomyosin structure organizationGO:00310321540.046
positive regulation of gene expressionGO:00106281120.046
ribonucleoside triphosphate metabolic processGO:0009199870.045
determination of adult lifespanGO:00083408120.045
regulation of purine nucleotide catabolic processGO:0033121350.045
nucleic acid templated transcriptionGO:00976591690.044
positive regulation of transportGO:0051050320.044
regulation of rna biosynthetic processGO:20011411650.044
phagocytosis engulfmentGO:0006911980.044
muscle cell differentiationGO:00426921710.044
nucleoside triphosphate metabolic processGO:0009141870.043
spermatogenesisGO:0007283410.043
regulation of multicellular organism growthGO:00400143730.043
apoptotic cell clearanceGO:00432771110.043
single organism intracellular transportGO:1902582700.043
divalent inorganic cation transportGO:0072511170.042
phagocytosisGO:00069091150.042
response to endogenous stimulusGO:0009719330.041
intracellular transportGO:0046907770.041
cell morphogenesisGO:00009021630.041
transmembrane transportGO:00550851100.041
response to oxygen containing compoundGO:1901700440.041
monovalent inorganic cation transportGO:0015672330.040
molting cycleGO:00423032810.040
positive regulation of multicellular organism growthGO:00400183520.040
oocyte developmentGO:0048599440.040
ribose phosphate metabolic processGO:0019693990.040
membrane organizationGO:00610241350.040
ribosome biogenesisGO:004225440.039
regulation of lipid metabolic processGO:001921640.039
purine nucleotide catabolic processGO:0006195750.039
negative regulation of neurogenesisGO:005076840.039
male gamete generationGO:0048232410.039
positive regulation of intracellular transportGO:003238820.039
regulation of cell communicationGO:00106461760.039
positive regulation of macromolecule biosynthetic processGO:00105571090.039
purine ribonucleoside catabolic processGO:0046130750.039
cellular component assembly involved in morphogenesisGO:00109271830.038
glycosyl compound catabolic processGO:1901658790.037
regulation of nervous system developmentGO:0051960410.037
genitalia developmentGO:00488067410.037
epithelium developmentGO:0060429680.037
hermaphrodite genitalia developmentGO:00400357340.037
ion transportGO:00068111130.037
cell proliferationGO:00082831160.036
positive regulation of molecular functionGO:0044093610.036
cyclic purine nucleotide metabolic processGO:005265220.036
positive regulation of cytosolic calcium ion concentrationGO:000720410.035
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.035
canonical wnt signaling pathwayGO:006007030.035
divalent metal ion transportGO:0070838170.035
regulation of neurogenesisGO:0050767400.035
positive regulation of neuron differentiationGO:004566640.034
metal ion homeostasisGO:0055065130.034
protein complex assemblyGO:00064611860.034
extracellular matrix organizationGO:003019860.034
peptidyl serine modificationGO:0018209200.034
regulation of nucleobase containing compound metabolic processGO:00192192220.034
regulation of protein localizationGO:0032880500.034
rna biosynthetic processGO:00327741690.033
organ morphogenesisGO:0009887670.033
small molecule metabolic processGO:00442811860.033
digestive system developmentGO:00551231220.032
membrane invaginationGO:0010324980.032
regulation of cell differentiationGO:0045595810.032
regulation of nucleotide metabolic processGO:0006140370.032
regulation of gtp catabolic processGO:0033124320.032
matingGO:0007618340.032
organonitrogen compound catabolic processGO:1901565900.032
regulation of cellular protein metabolic processGO:0032268750.032
nucleobase containing compound catabolic processGO:00346551140.032
purine nucleoside triphosphate metabolic processGO:0009144870.031
negative regulation of signalingGO:0023057610.031
regulation of cell proliferationGO:00421271050.031
regulation of nucleoside metabolic processGO:0009118370.031
nucleoside triphosphate catabolic processGO:0009143720.030
reproductive system developmentGO:00614588500.030
dauer larval developmentGO:0040024920.030
posttranscriptional gene silencingGO:00164411430.030
regulation of cell deathGO:0010941650.030
tube morphogenesisGO:0035239790.029
gonad developmentGO:00084068400.029
cellular response to inorganic substanceGO:007124130.029
negative regulation of cellular protein metabolic processGO:0032269270.029
positive regulation of hydrolase activityGO:0051345380.029
purine nucleoside triphosphate catabolic processGO:0009146720.029
response to extracellular stimulusGO:0009991380.029
neurological system processGO:0050877530.028
positive regulation of transcription dna templatedGO:00458931020.028
positive regulation of secretionGO:0051047170.028
regulation of pharyngeal pumpingGO:0043051360.028
larval behaviorGO:003053750.028
muscle contractionGO:0006936430.028
pharyngeal pumpingGO:0043050580.027
organic substance catabolic processGO:19015752940.027
response to temperature stimulusGO:0009266660.027
cell fate commitmentGO:00451651390.027
epithelial cell proliferationGO:005067310.027
adult locomotory behaviorGO:000834410.027
organelle fissionGO:00482853630.027
oxoacid metabolic processGO:0043436470.027
response to nutrient levelsGO:0031667350.027
rhythmic behaviorGO:000762230.027
regulation of cell projection organizationGO:0031344380.027
tissue developmentGO:00098881120.026
ribonucleoside catabolic processGO:0042454770.026
response to organonitrogen compoundGO:0010243150.026
nucleotide metabolic processGO:00091171080.026
response to external stimulusGO:00096052890.026
reproductive structure developmentGO:00486088500.026
aromatic compound catabolic processGO:00194391160.026
regulation of gene expression epigeneticGO:00400291630.026
regulation of transportGO:0051049910.026
organophosphate catabolic processGO:0046434810.026
cellular protein complex assemblyGO:00436231780.026
regulation of sequence specific dna binding transcription factor activityGO:005109030.026
regulation of development heterochronicGO:0040034180.026
protein oligomerizationGO:005125940.026
feeding behaviorGO:0007631700.026
heterocycle catabolic processGO:00467001190.025
cell maturationGO:0048469260.025
regulation of cellular ketone metabolic processGO:001056530.025
calcium ion transportGO:0006816160.025
male mating behaviorGO:0060179260.025
oocyte differentiationGO:0009994450.025
cellular macromolecular complex assemblyGO:00346221840.025
cellular nitrogen compound biosynthetic processGO:00442711920.025
organic substance transportGO:00717021130.025
eating behaviorGO:0042755590.025
negative regulation of locomotionGO:0040013210.025
generation of precursor metabolites and energyGO:0006091180.025
organelle localizationGO:00516401270.024
fertilizationGO:0009566630.024
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.024
carbohydrate derivative catabolic processGO:1901136820.024
positive regulation of protein metabolic processGO:0051247450.024
embryonic body morphogenesisGO:0010172490.024
negative regulation of cellular biosynthetic processGO:0031327650.024
negative regulation of signal transductionGO:0009968600.024
regulation of cell morphogenesisGO:0022604400.024
posttranscriptional gene silencing by rnaGO:00351941430.024
rna interferenceGO:00162461370.024
negative regulation of nitrogen compound metabolic processGO:0051172630.024
regulation of cation channel activityGO:200125730.024
nucleotide catabolic processGO:0009166770.023
synaptic growth at neuromuscular junctionGO:005112410.023
gene silencing by rnaGO:00310471430.023
bmp signaling pathwayGO:003050930.023
cellular ion homeostasisGO:0006873110.023
positive regulation of ion transportGO:0043270100.023
mitotic nuclear divisionGO:0007067890.022
regulation of feeding behaviorGO:0060259380.022
peptidyl serine phosphorylationGO:0018105200.022
positive regulation of protein transportGO:005122240.022
response to ketoneGO:190165410.022
nuclear migrationGO:0007097540.022
ribonucleoside triphosphate catabolic processGO:0009203720.022
regulation of nuclear divisionGO:00517831150.022
gene silencingGO:00164581430.022
organic cyclic compound catabolic processGO:19013611190.021
regulation of cellular amino acid metabolic processGO:000652100.021
regulation of behaviorGO:0050795970.021
cellular amine metabolic processGO:0044106150.021
myosin filament assemblyGO:00310341380.021
cellular nitrogen compound catabolic processGO:00442701190.021
detection of external stimulusGO:000958140.021
regulation of synapse assemblyGO:005196320.021
regulation of lipid transportGO:003236840.021
regulation of hydrolase activityGO:0051336450.020
negative regulation of transcription dna templatedGO:0045892530.020
pigmentationGO:004347320.020
response to organic cyclic compoundGO:0014070100.020
positive regulation of cell communicationGO:0010647690.020
regulation of epithelial cell proliferationGO:005067810.020
system processGO:00030081360.020
muscle system processGO:0003012430.020
long term memoryGO:000761620.020
negative regulation of nucleobase containing compound metabolic processGO:0045934630.020
purine ribonucleoside triphosphate catabolic processGO:0009207720.020
regulation of purine nucleotide metabolic processGO:1900542370.020
regulation of bmp signaling pathwayGO:003051030.020
purine ribonucleoside triphosphate metabolic processGO:0009205870.020
molting cycle collagen and cuticulin based cuticleGO:00189962810.020
ribonucleoprotein complex assemblyGO:002261840.019
response to endoplasmic reticulum stressGO:0034976710.019
negative regulation of cell communicationGO:0010648610.019
regulation of organelle organizationGO:00330431640.019
microtubule based processGO:00070171820.019
innate immune responseGO:00450871900.019
regulation of cellular amine metabolic processGO:003323800.019
positive regulation of cell deathGO:0010942380.019
purine ribonucleotide catabolic processGO:0009154750.019
negative regulation of response to external stimulusGO:003210230.018
purine ribonucleoside metabolic processGO:0046128920.018
organ growthGO:003526550.018
positive regulation of neurogenesisGO:005076940.018
nucleoside catabolic processGO:0009164780.018
response to heatGO:0009408500.018
cellular metal ion homeostasisGO:000687570.018
meiotic cell cycle processGO:19030461700.018
single organism biosynthetic processGO:0044711910.018
purine nucleoside metabolic processGO:0042278920.018
organic acid metabolic processGO:0006082470.018
regulation of mitotic cell cycleGO:0007346760.018
regulation of epithelial cell differentiationGO:003085640.018
purine nucleoside catabolic processGO:0006152750.018
neurotransmitter secretionGO:0007269260.017
establishment of organelle localizationGO:00516561230.017
regulation of protein targetingGO:190353330.017
striated muscle myosin thick filament assemblyGO:00716881380.017
regulation of response to stressGO:0080134280.017
peptidyl amino acid modificationGO:0018193580.017
positive regulation of protein modification processGO:0031401290.017
peptidyl threonine modificationGO:0018210140.017
regulation of cellular localizationGO:0060341420.017

pde-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
musculoskeletal system diseaseDOID:1700.028
disease of cellular proliferationDOID:1456600.021
nervous system diseaseDOID:86300.021
organ system cancerDOID:005068600.017
cancerDOID:16200.017