Caenorhabditis elegans

98 known processes

ref-1 (CELE_T01E8.2)

Protein REF-1

ref-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
embryo development ending in birth or egg hatchingGO:000979229920.500
embryo developmentGO:000979030520.297
positive regulation of cellular biosynthetic processGO:00313281090.266
growthGO:00400075620.252
locomotionGO:004001116340.217
positive regulation of multicellular organismal processGO:00512404170.203
positive regulation of rna metabolic processGO:00512541030.195
sex differentiationGO:00075489090.194
neuron projection guidanceGO:0097485820.183
regulation of multicellular organismal developmentGO:20000263170.179
organic cyclic compound biosynthetic processGO:19013621950.172
regulation of multicellular organismal processGO:00512397260.165
cell developmentGO:00484686960.164
positive regulation of rna biosynthetic processGO:19026801020.164
cellular component morphogenesisGO:00329893180.162
nucleic acid templated transcriptionGO:00976591690.162
tube developmentGO:00352951260.153
single organism reproductive processGO:004470211960.151
multicellular organismal reproductive processGO:00486098150.148
nervous system developmentGO:00073992530.145
multicellular organism growthGO:00352643850.145
positive regulation of gene expressionGO:00106281120.131
regulation of cell differentiationGO:0045595810.129
multi organism reproductive processGO:00447038670.129
determination of adult lifespanGO:00083408120.128
agingGO:00075688120.122
developmental process involved in reproductionGO:000300611650.122
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.115
multicellular organismal agingGO:00102598120.110
behaviorGO:00076105270.110
sensory organ morphogenesisGO:009059620.109
regulation of nucleobase containing compound metabolic processGO:00192192220.108
regulation of cellular metabolic processGO:00313233050.108
organ developmentGO:004851311020.106
regulation of biological qualityGO:00650087410.103
gonad developmentGO:00084068400.102
positive regulation of multicellular organism growthGO:00400183520.102
regulation of nucleic acid templated transcriptionGO:19035061650.101
reproductive structure developmentGO:00486088500.101
regulation of macromolecule metabolic processGO:00602554210.101
multi multicellular organism processGO:00447063900.101
tissue developmentGO:00098881120.100
development of primary sexual characteristicsGO:00451378400.100
positive regulation of growthGO:00459273690.098
positive regulation of macromolecule metabolic processGO:00106041490.097
negative regulation of biological processGO:00485195670.094
heterocycle biosynthetic processGO:00181301870.093
generation of neuronsGO:00486992350.092
positive regulation of developmental processGO:00510944080.091
digestive tract developmentGO:00485651220.090
post embryonic developmentGO:000979121520.090
cell projection organizationGO:00300302310.089
regulation of growthGO:00400084090.089
negative regulation of multicellular organismal processGO:00512412360.089
positive regulation of transcription dna templatedGO:00458931020.088
positive regulation of developmental growthGO:00486393540.088
macromolecule localizationGO:00330367710.086
organelle organizationGO:00069967830.086
neurogenesisGO:00220082360.084
ovipositionGO:00189913640.083
positive regulation of transcription from rna polymerase ii promoter in response to osmotic stressGO:006139310.083
reproductive system developmentGO:00614588500.082
maintenance of locationGO:00512355800.081
regulation of cellular biosynthetic processGO:00313261890.081
regulation of rna biosynthetic processGO:20011411650.080
lipid localizationGO:00108765730.080
negative regulation of developmental processGO:00510932270.080
positive regulation of neurogenesisGO:005076940.079
regulation of developmental processGO:00507936840.078
negative regulation of macromolecule metabolic processGO:00106052290.078
positive regulation of nucleic acid templated transcriptionGO:19035081020.078
aromatic compound biosynthetic processGO:00194381920.074
regulation of developmental growthGO:00486383890.073
regulation of metabolic processGO:00192224780.073
axon guidanceGO:0007411820.073
digestive system developmentGO:00551231220.072
cellular biosynthetic processGO:00442493150.070
lipid storageGO:00199155650.070
anatomical structure formation involved in morphogenesisGO:00486462500.069
transcription from rna polymerase ii promoterGO:00063661490.068
multi organism reproductive behaviorGO:00447053870.067
multicellular organism reproductionGO:00325048190.065
endocytosisGO:00068978190.064
sexual reproductionGO:00199535460.062
reproductive behaviorGO:00190983870.061
single organism signalingGO:00447004010.060
regulation of biosynthetic processGO:00098891890.060
regulation of multicellular organism growthGO:00400143730.058
neuron developmentGO:00486661990.058
multicellular organismal reproductive behaviorGO:00330573840.058
regulation of transcription dna templatedGO:00063551640.056
neuron projection developmentGO:00311751870.055
rna metabolic processGO:00160702280.055
rna biosynthetic processGO:00327741690.054
multi organism behaviorGO:00517053890.053
cell motilityGO:00488703130.053
positive regulation of macromolecule biosynthetic processGO:00105571090.053
neuron recognitionGO:0008038830.053
taxisGO:00423301280.052
developmental growthGO:00485894120.050
gene expressionGO:00104674120.050
cell deathGO:00082195470.049
nucleobase containing compound metabolic processGO:00061394060.049
regulation of nematode larval developmentGO:00610622600.049
neuron projection morphogenesisGO:00488121140.049
cell proliferationGO:00082831160.049
positive regulation of transcription from rna polymerase ii promoter in response to salt stressGO:003625110.049
genitalia developmentGO:00488067410.048
signal transductionGO:00071653170.048
negative regulation of vulval developmentGO:00400272060.048
cellular nitrogen compound biosynthetic processGO:00442711920.047
positive regulation of cellular metabolic processGO:00313251780.047
regulation of primary metabolic processGO:00800902920.047
transcription dna templatedGO:00063511680.046
response to external stimulusGO:00096052890.046
secretionGO:00469031470.045
neuroblast fate determinationGO:000740010.045
body morphogenesisGO:00101716200.044
molting cycleGO:00423032810.043
head developmentGO:006032210.043
protein modification processGO:00362112070.043
receptor mediated endocytosisGO:00068987150.042
digestive tract morphogenesisGO:0048546760.042
regulation of locomotionGO:00400121610.042
positive regulation of neuron differentiationGO:004566640.041
response to chemicalGO:00422213560.041
macromolecule biosynthetic processGO:00090592500.041
hermaphrodite genitalia developmentGO:00400357340.040
embryonic morphogenesisGO:00485981520.040
regulation of cell cycle processGO:00105641450.040
cellular macromolecular complex assemblyGO:00346221840.040
regulation of gene expressionGO:00104683660.039
negative regulation of rna biosynthetic processGO:1902679530.039
positive regulation of nucleobase containing compound metabolic processGO:00459351340.039
secretion by cellGO:00329401380.039
dauer larval developmentGO:0040024920.039
male sex differentiationGO:0046661860.038
inductive cell migrationGO:00400391450.038
transportGO:000681010930.037
mesodermal cell differentiationGO:0048333150.037
regulation of cell proliferationGO:00421271050.036
positive regulation of biosynthetic processGO:00098911090.036
protein complex biogenesisGO:00702711860.035
vulval developmentGO:00400253330.035
striated muscle myosin thick filament assemblyGO:00716881380.034
post embryonic organ developmentGO:00485693360.034
establishment of localizationGO:005123411710.034
molting cycle collagen and cuticulin based cuticleGO:00189962810.033
axon developmentGO:00615641630.033
signalingGO:00230524010.033
positive regulation of transcription from rna polymerase ii promoter involved in defense response to fungusGO:190124410.033
positive regulation of metabolic processGO:00098931870.033
cell surface receptor signaling pathwayGO:00071661490.031
muscle structure developmentGO:00610611910.031
calcium mediated signalingGO:001972230.031
male anatomical structure morphogenesisGO:0090598780.031
negative regulation of post embryonic developmentGO:00485812080.031
regulation of meiosisGO:0040020940.030
cellular process involved in reproduction in multicellular organismGO:00224123510.030
vesicle mediated transportGO:00161928520.030
regulation of localizationGO:00328791940.030
regulation of post embryonic developmentGO:00485802600.030
positive regulation of cellular processGO:00485223320.030
system processGO:00030081360.030
cellular protein modification processGO:00064642070.030
pharynx developmentGO:0060465510.030
programmed cell deathGO:00125015000.030
muscle cell developmentGO:00550011580.029
cell fate commitmentGO:00451651390.029
tube morphogenesisGO:0035239790.029
cell migrationGO:00164773060.029
negative regulation of cellular processGO:00485232390.029
actomyosin structure organizationGO:00310321540.029
muscle cell differentiationGO:00426921710.029
regulation of transcription from rna polymerase ii promoter in response to osmotic stressGO:006139210.029
single organism organelle organizationGO:19025895010.029
myosin filament assemblyGO:00310341380.028
axonal fasciculationGO:0007413790.028
biosynthetic processGO:00090583230.028
neuron differentiationGO:00301822170.028
cell cycle processGO:00224024820.028
positive regulation of transcription from rna polymerase ii promoter in response to stressGO:003600320.028
regulation of cellular macromolecule biosynthetic processGO:20001121880.028
striated muscle cell differentiationGO:00511461580.027
myosin filament organizationGO:00310331380.027
regulation of signalingGO:00230511720.027
actin cytoskeleton organizationGO:00300361840.027
meiotic cell cycleGO:00513213350.027
protein metabolic processGO:00195384220.027
organic substance transportGO:00717021130.027
dendrite developmentGO:0016358420.027
response to acid chemicalGO:000110140.027
negative regulation of neurogenesisGO:005076840.027
negative regulation of response to stimulusGO:0048585730.026
single organism transportGO:00447654470.025
regulation of transcription from rna polymerase ii promoter in response to stressGO:004361820.025
pattern specification processGO:0007389590.025
negative regulation of macromolecule biosynthetic processGO:0010558650.025
regulation of sequence specific dna binding transcription factor activityGO:005109030.025
cell fate commitment involved in formation of primary germ layerGO:0060795330.025
single organism behaviorGO:0044708830.025
nucleobase containing compound biosynthetic processGO:00346541840.024
hormone transportGO:000991420.024
negative regulation of metabolic processGO:00098922400.024
macromolecular complex subunit organizationGO:00439333200.024
cytoskeleton organizationGO:00070103390.024
mitotic cell cycle processGO:19030471940.024
establishment of localization in cellGO:00516493180.024
negative regulation of signal transductionGO:0009968600.023
mesodermal cell fate specificationGO:0007501130.023
regulation of neuron differentiationGO:0045664400.023
endodermal cell fate determinationGO:000749320.023
protein complex subunit organizationGO:00718222800.023
positive regulation of nitrogen compound metabolic processGO:00511731340.023
regulation of nuclear divisionGO:00517831150.022
positive regulation of transcription from rna polymerase ii promoter in response to increased saltGO:006140410.022
regulation of cell communicationGO:00106461760.022
single organism localizationGO:19025785180.022
cellular protein complex assemblyGO:00436231780.022
enzyme linked receptor protein signaling pathwayGO:0007167500.022
organic substance biosynthetic processGO:19015763230.022
cell type specific apoptotic processGO:009728540.022
myofibril assemblyGO:00302391540.022
cellular macromolecule biosynthetic processGO:00346452470.022
negative regulation of cellular metabolic processGO:0031324950.021
chemotaxisGO:00069351200.021
negative regulation of nematode larval developmentGO:00610642080.021
bmp signaling pathwayGO:003050930.021
macromolecular complex assemblyGO:00650031930.021
regulation of neurogenesisGO:0050767400.021
deathGO:00162655470.021
macromolecule modificationGO:00434122180.021
localization of cellGO:00516743130.021
nucleic acid metabolic processGO:00903042990.021
immune responseGO:00069551920.020
cell cycleGO:00070495260.020
positive regulation of cell cycleGO:0045787550.020
chemosensory behaviorGO:0007635330.020
actin filament based processGO:00300291910.020
cell recognitionGO:0008037850.020
cellular component biogenesisGO:00440852970.020
regulation of meiotic cell cycleGO:00514451360.020
striated muscle cell developmentGO:00550021570.020
epidermal cell fate specificationGO:000995750.019
protein complex assemblyGO:00064611860.019
peptide hormone secretionGO:003007220.019
nematode male tail tip morphogenesisGO:0045138770.019
cellular response to organic substanceGO:00713101190.019
meiotic nuclear divisionGO:00071263000.019
regulation of nitrogen compound metabolic processGO:00511712220.019
apoptotic processGO:00069154780.019
organelle assemblyGO:00709252140.018
regulation of reproductive processGO:2000241660.018
homeostatic processGO:0042592510.018
response to organic substanceGO:00100331310.018
response to oxygen containing compoundGO:1901700440.018
stem cell proliferationGO:007208990.018
regulation of cell developmentGO:0060284490.018
negative regulation of nitrogen compound metabolic processGO:0051172630.018
cellular component movementGO:00069283880.017
embryonic body morphogenesisGO:0010172490.017
negative regulation of nucleobase containing compound metabolic processGO:0045934630.017
cellular localizationGO:00516413600.017
cell projection morphogenesisGO:00488581480.017
catabolic processGO:00090563180.017
synaptic transmissionGO:00072681060.017
cell part morphogenesisGO:00329901520.017
axonogenesisGO:00074091020.017
defecationGO:0030421470.017
organelle fissionGO:00482853630.017
regulation of epithelial cell differentiationGO:003085640.017
cellular component assembly involved in morphogenesisGO:00109271830.017
protein catabolic processGO:00301631620.016
oogenesisGO:00484772290.016
response to woundingGO:000961140.016
cellular response to stressGO:00335541620.016
cellular hyperosmotic salinity responseGO:007147510.016
regulation of gastrulationGO:001047040.016
regulation of response to stimulusGO:00485832430.016
nitrogen compound transportGO:0071705490.016
cellular component assemblyGO:00226072930.016
neuron fate specificationGO:004866580.015
regulation of rna metabolic processGO:00512521730.015
regulation of transcription from rna polymerase ii promoterGO:00063571450.015
excretionGO:0007588490.015
regulation of axon extensionGO:0030516200.015
regulation of system processGO:0044057270.015
regulation of nucleocytoplasmic transportGO:004682230.015
cellular protein metabolic processGO:00442672790.015
regulation of bmp signaling pathwayGO:003051030.015
germ cell developmentGO:00072813510.015
epithelial tube morphogenesisGO:006056210.014
neurological system processGO:0050877530.014
notch signaling pathwayGO:0007219220.014
gamete generationGO:00072764610.014
positive regulation of transcription from rna polymerase ii promoter involved in defense response to gram negative bacteriumGO:190209740.014
regulation of vulval developmentGO:00400282480.014
negative regulation of cellular macromolecule biosynthetic processGO:2000113650.014
regulation of cation channel activityGO:200125730.013
regulation of cellular component movementGO:0051270620.013
tissue morphogenesisGO:0048729650.013
response to biotic stimulusGO:00096071010.013
negative regulation of cell communicationGO:0010648610.013
negative regulation of cellular biosynthetic processGO:0031327650.013
regulation of cellular component organizationGO:00511282480.013
developmental maturationGO:0021700260.013
negative regulation of transcription dna templatedGO:0045892530.013
cell divisionGO:00513012620.013
neuron projection extensionGO:1990138370.013
inactivation of mapkkk activityGO:005139020.013
regulation of cell projection organizationGO:0031344380.013
protein localizationGO:00081042050.013
small molecule metabolic processGO:00442811860.012
regulation of organelle organizationGO:00330431640.012
regulation of neuromuscular synaptic transmissionGO:190007310.012
positive regulation of epithelial cell proliferationGO:005067910.012
response to abiotic stimulusGO:00096281520.012
cuticle developmentGO:00423351000.012
positive regulation of mitotic sister chromatid separationGO:190197010.012
muscle tissue developmentGO:006053710.012
organism emergence from protective structureGO:0071684480.012
organic substance catabolic processGO:19015752940.012
signal releaseGO:0023061280.012
sex determinationGO:0007530600.012
memoryGO:000761330.012
macromolecule catabolic processGO:00090572020.012
axon extension involved in axon guidanceGO:0048846130.012
negative regulation of gene expressionGO:00106292170.012
cellular response to chemical stimulusGO:00708871290.012
regulation of protein import into nucleusGO:004230630.012
insulin secretionGO:003007320.012
regulation of cell divisionGO:00513021420.012
regulation of synaptic plasticityGO:004816710.011
negative regulation of signalingGO:0023057610.011
response to other organismGO:00517071010.011
gabaergic neuron differentiationGO:009715410.011
negative regulation of mitotic cell cycleGO:0045930420.011
asymmetric cell divisionGO:0008356360.011
regulation of synaptic transmissionGO:0050804340.011
negative regulation of neuron differentiationGO:004566540.011
positive regulation of post embryonic developmentGO:0048582540.011
female gamete generationGO:00072922540.011
regulation of signal transductionGO:00099661350.011
hormone secretionGO:004687920.011
regenerationGO:003109940.011
adult behaviorGO:003053430.011
eating behaviorGO:0042755590.011
regulation of mitotic cell cycleGO:0007346760.011
ion transmembrane transportGO:0034220910.011
positive regulation of nematode larval developmentGO:0061063540.011
response to external biotic stimulusGO:00432071010.011
mesoderm morphogenesisGO:0048332240.011
positive regulation of intracellular transportGO:003238820.011
cell maturationGO:0048469260.011
intracellular signal transductionGO:0035556960.011
positive regulation of protein transportGO:005122240.011
membrane fusionGO:0061025160.011
negative regulation of nucleic acid templated transcriptionGO:1903507530.010
gastrulationGO:0007369580.010
regulation of defecation rhythmGO:200074630.010
regulation of cell morphogenesisGO:0022604400.010
regulation of cell motilityGO:2000145570.010
cell cell signalingGO:00072671180.010
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.010
neuroblast proliferationGO:000740590.010

ref-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.019
disease of metabolismDOID:001466700.012
cancerDOID:16200.011
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.011