Caenorhabditis elegans

217 known processes

let-60 (CELE_ZK792.6)

Protein LET-60

let-60 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
axonogenesisGO:00074091020.964
positive regulation of locomotionGO:0040017420.958
Human
cell part morphogenesisGO:00329901520.950
neuron projection guidanceGO:0097485820.944
cell morphogenesisGO:00009021630.942
Fly
cell fate commitmentGO:00451651390.920
positive regulation of nematode larval developmentGO:0061063540.919
developmental process involved in reproductionGO:000300611650.902
neuron projection morphogenesisGO:00488121140.881
axon guidanceGO:0007411820.881
response to fibroblast growth factorGO:007177450.879
positive regulation of rna biosynthetic processGO:19026801020.878
Human
regulation of vulval developmentGO:00400282480.877
cell projection morphogenesisGO:00488581480.873
establishment of localizationGO:005123411710.856
cell morphogenesis involved in neuron differentiationGO:00486671110.851
Fly
cell motilityGO:00488703130.829
Human Fly
taxisGO:00423301280.810
regulation of cell migrationGO:0030334550.807
Human
locomotionGO:004001116340.807
post embryonic developmentGO:000979121520.804
regulation of nitrogen compound metabolic processGO:00511712220.802
cell projection organizationGO:00300302310.796
embryo development ending in birth or egg hatchingGO:000979229920.795
response to woundingGO:000961140.790
Human
sex differentiationGO:00075489090.789
epidermis developmentGO:0008544240.770
positive regulation of signalingGO:0023056660.764
Human Mouse Fly
fibroblast growth factor receptor signaling pathwayGO:000854350.749
cell surface receptor signaling pathwayGO:00071661490.746
organ developmentGO:004851311020.741
localization of cellGO:00516743130.740
Human Fly
cellular response to growth factor stimulusGO:0071363180.733
regulation of cell fate commitmentGO:0010453220.730
signalingGO:00230524010.727
cellular component morphogenesisGO:00329893180.726
Fly
cell morphogenesis involved in differentiationGO:00009041120.723
Fly
guanosine containing compound metabolic processGO:1901068490.719
positive regulation of ras protein signal transductionGO:004657970.713
Mouse
cell migrationGO:00164773060.709
Human Fly
chemotaxisGO:00069351200.697
positive regulation of vulval developmentGO:0040026520.696
regulation of nucleic acid templated transcriptionGO:19035061650.689
Human
reproductive structure developmentGO:00486088500.671
positive regulation of signal transductionGO:0009967400.670
Human Mouse Fly
positive regulation of cellular processGO:00485223320.669
positive regulation of transcription dna templatedGO:00458931020.664
Human
transportGO:000681010930.663
skin developmentGO:0043588240.662
single organism reproductive processGO:004470211960.655
development of primary sexual characteristicsGO:00451378400.652
generation of neuronsGO:00486992350.650
Fly
regulation of cell morphogenesisGO:0022604400.647
positive regulation of post embryonic developmentGO:0048582540.644
positive regulation of cell migrationGO:003033530.642
Human
tissue developmentGO:00098881120.633
Mouse Fly
erbb signaling pathwayGO:003812790.628
wnt signaling pathwayGO:0016055270.625
vulval developmentGO:00400253330.619
gonad developmentGO:00084068400.614
embryo developmentGO:000979030520.607
purine ribonucleoside triphosphate catabolic processGO:0009207720.605
ribonucleotide catabolic processGO:0009261750.598
ribonucleoside triphosphate catabolic processGO:0009203720.593
cell developmentGO:00484686960.591
skeletal muscle organ developmentGO:006053830.589
Mouse
regulation of nematode larval developmentGO:00610622600.587
positive regulation of nucleobase containing compound metabolic processGO:00459351340.580
neuron developmentGO:00486661990.579
Fly
positive regulation of cell communicationGO:0010647690.575
Human Mouse Fly
carbohydrate derivative catabolic processGO:1901136820.574
positive regulation of nitrogen compound metabolic processGO:00511731340.570
regulation of locomotionGO:00400121610.560
Human
sexual reproductionGO:00199535460.557
gastrulationGO:0007369580.556
Fly
multicellular organism reproductionGO:00325048190.551
positive regulation of transcription from rna polymerase ii promoterGO:0045944980.550
Human
regulation of signalingGO:00230511720.549
gamete generationGO:00072764610.547
ribonucleoside triphosphate metabolic processGO:0009199870.542
single organism localizationGO:19025785180.541
response to endogenous stimulusGO:0009719330.534
negative regulation of biological processGO:00485195670.532
transmembrane receptor protein tyrosine kinase signaling pathwayGO:0007169340.531
regulation of cell fate specificationGO:0042659220.531
head developmentGO:006032210.524
positive regulation of small gtpase mediated signal transductionGO:005105770.522
Mouse
nucleotide metabolic processGO:00091171080.517
axon developmentGO:00615641630.517
multicellular organismal reproductive processGO:00486098150.516
cell growthGO:0016049440.515
Fly
purine containing compound catabolic processGO:0072523750.513
regulation of multicellular organismal developmentGO:20000263170.513
glycosyl compound metabolic processGO:19016571000.509
reproductive system developmentGO:00614588500.506
nucleoside triphosphate catabolic processGO:0009143720.501
organonitrogen compound catabolic processGO:1901565900.494
multicellular organismal reproductive behaviorGO:00330573840.493
positive regulation of cellular metabolic processGO:00313251780.488
muscle tissue developmentGO:006053710.487
Mouse
cellular component movementGO:00069283880.480
Human Fly
positive regulation of nucleic acid templated transcriptionGO:19035081020.473
Human
regulation of gtp catabolic processGO:0033124320.466
nucleic acid templated transcriptionGO:00976591690.465
Human
regulation of developmental processGO:00507936840.463
establishment of vesicle localizationGO:0051650230.461
genitalia developmentGO:00488067410.460
response to organic substanceGO:00100331310.458
regulation of rna metabolic processGO:00512521730.455
Human
regulation of cellular metabolic processGO:00313233050.448
regulation of filopodium assemblyGO:005148920.447
enzyme linked receptor protein signaling pathwayGO:0007167500.446
autophagyGO:0006914290.443
Fly
positive regulation of intracellular signal transductionGO:1902533240.440
Human Mouse Fly
nucleotide catabolic processGO:0009166770.436
response to chemicalGO:00422213560.426
nucleobase containing compound metabolic processGO:00061394060.426
positive regulation of macromolecule biosynthetic processGO:00105571090.423
Human
regulation of nucleobase containing compound metabolic processGO:00192192220.420
nucleoside triphosphate metabolic processGO:0009141870.419
nucleic acid metabolic processGO:00903042990.418
Human
heterocycle catabolic processGO:00467001190.415
small gtpase mediated signal transductionGO:0007264320.414
Human Mouse
regulation of cellular component movementGO:0051270620.409
Human
positive regulation of neurogenesisGO:005076940.408
Fly
nucleobase containing compound catabolic processGO:00346551140.407
cellular process involved in reproduction in multicellular organismGO:00224123510.403
catabolic processGO:00090563180.400
regulation of rna biosynthetic processGO:20011411650.399
Human
regulation of response to stimulusGO:00485832430.399
single organism signalingGO:00447004010.395
nervous system developmentGO:00073992530.394
Fly
ras protein signal transductionGO:0007265310.387
Human Mouse
male sex differentiationGO:0046661860.385
protein modification processGO:00362112070.380
Human
regulation of organ morphogenesisGO:200002740.376
Fly
digestive tract developmentGO:00485651220.374
Fly
neuron differentiationGO:00301822170.373
Fly
tissue morphogenesisGO:0048729650.371
Mouse
behaviorGO:00076105270.368
Mouse
mesodermal cell differentiationGO:0048333150.367
motor neuron axon guidanceGO:0008045130.364
regulation of cell motilityGO:2000145570.364
Human
nucleoside phosphate catabolic processGO:1901292770.363
positive regulation of biosynthetic processGO:00098911090.362
Human
hermaphrodite genitalia developmentGO:00400357340.358
response to growth factorGO:0070848180.354
neurogenesisGO:00220082360.353
Fly
meiotic cell cycleGO:00513213350.352
organelle organizationGO:00069967830.351
Human Mouse
neuron projection developmentGO:00311751870.351
regulation of macromolecule biosynthetic processGO:00105561890.348
Human
purine nucleotide catabolic processGO:0006195750.346
post embryonic organ developmentGO:00485693360.343
regulation of primary metabolic processGO:00800902920.343
positive regulation of purine nucleotide catabolic processGO:0033123280.338
regulation of cellular component organizationGO:00511282480.336
organic cyclic compound biosynthetic processGO:19013621950.334
Human
regulation of signal transductionGO:00099661350.334
positive regulation of response to stimulusGO:0048584550.334
Human Mouse Fly
meiotic nuclear divisionGO:00071263000.333
pattern specification processGO:0007389590.332
Fly
negative regulation of cellular processGO:00485232390.330
Human Mouse Fly
programmed cell deathGO:00125015000.329
Mouse Fly
anterior posterior axis specificationGO:0009948170.326
protein complex subunit organizationGO:00718222800.319
embryonic pattern specificationGO:0009880210.319
protein metabolic processGO:00195384220.319
Human
epidermal growth factor receptor signaling pathwayGO:000717390.315
positive regulation of neuron differentiationGO:004566640.314
Fly
regulation of transcription dna templatedGO:00063551640.311
Human
positive regulation of cell morphogenesis involved in differentiationGO:001077040.310
male anatomical structure morphogenesisGO:0090598780.309
membrane organizationGO:00610241350.308
response to external stimulusGO:00096052890.291
Fly
sensory organ morphogenesisGO:009059620.289
Fly
regulation of multicellular organismal processGO:00512397260.289
rna metabolic processGO:00160702280.287
Human
macromolecule catabolic processGO:00090572020.285
regulation of meiosisGO:0040020940.284
positive regulation of ras gtpase activityGO:0032320190.282
purine ribonucleoside metabolic processGO:0046128920.281
ovipositionGO:00189913640.280
signal transductionGO:00071653170.277
purine nucleoside triphosphate metabolic processGO:0009144870.276
regulation of cell communicationGO:00106461760.276
cellular protein metabolic processGO:00442672790.276
Human
regulation of cell differentiationGO:0045595810.275
nucleoside phosphate metabolic processGO:00067531080.273
vesicle mediated transportGO:00161928520.272
single organism transportGO:00447654470.271
reproductive behaviorGO:00190983870.270
cellular response to organic substanceGO:00713101190.270
regulation of neuron differentiationGO:0045664400.270
Fly
establishment of localization in cellGO:00516493180.270
regulation of molecular functionGO:0065009890.270
ribonucleoside catabolic processGO:0042454770.269
rho protein signal transductionGO:000726620.267
purine nucleoside metabolic processGO:0042278920.266
macromolecule biosynthetic processGO:00090592500.266
Human
cellular response to endogenous stimulusGO:0071495320.266
cellular macromolecule biosynthetic processGO:00346452470.265
Human
positive regulation of cell cycleGO:0045787550.263
positive regulation of metabolic processGO:00098931870.259
regionalizationGO:0003002310.259
Fly
anterior posterior pattern specificationGO:0009952270.259
regulation of nucleoside metabolic processGO:0009118370.257
organophosphate catabolic processGO:0046434810.257
ribonucleotide metabolic processGO:0009259990.251
regulation of post embryonic developmentGO:00485802600.251
regulation of meiotic cell cycleGO:00514451360.251
gtp catabolic processGO:0006184460.248
actin filament based processGO:00300291910.248
Human Mouse
regulation of cellular biosynthetic processGO:00313261890.246
Human
developmental growth involved in morphogenesisGO:0060560370.243
purine ribonucleotide catabolic processGO:0009154750.238
vesicle localizationGO:0051648240.231
regulation of cell projection organizationGO:0031344380.230
positive regulation of molecular functionGO:0044093610.229
regulation of response to woundingGO:190303410.229
Human
regulation of cell cycleGO:00517261940.227
Human
inductive cell migrationGO:00400391450.226
glycosyl compound catabolic processGO:1901658790.224
secretion by cellGO:00329401380.223
regulation of gtpase activityGO:0043087300.221
regulation of cell projection assemblyGO:006049130.216
Human
positive regulation of gene expressionGO:00106281120.216
Human Mouse
regulation of anatomical structure morphogenesisGO:0022603510.216
Fly
agingGO:00075688120.215
Human Mouse Worm
aromatic compound biosynthetic processGO:00194381920.214
Human
cell type specific apoptotic processGO:009728540.213
Mouse
filopodium assemblyGO:004684720.212
regenerationGO:003109940.208
regulation of metabolic processGO:00192224780.208
regulation of ras gtpase activityGO:0032318210.206
germ cell developmentGO:00072813510.204
protein catabolic processGO:00301631620.204
cell cycleGO:00070495260.203
Human
regulation of cell adhesionGO:003015560.202
system processGO:00030081360.201
Mouse
organic substance catabolic processGO:19015752940.200
positive regulation of catalytic activityGO:0043085590.199
memoryGO:000761330.197
purine nucleoside triphosphate catabolic processGO:0009146720.197
body morphogenesisGO:00101716200.196
mesoderm morphogenesisGO:0048332240.195
digestive tract morphogenesisGO:0048546760.195
Fly
gene expressionGO:00104674120.193
Human Mouse
rna biosynthetic processGO:00327741690.192
Human
epidermal cell differentiationGO:000991370.191
regulation of cellular macromolecule biosynthetic processGO:20001121880.191
Human
cellular biosynthetic processGO:00442493150.189
Human
cellular nitrogen compound biosynthetic processGO:00442711920.189
Human
regulation of biosynthetic processGO:00098891890.187
Human
regulation of ras protein signal transductionGO:0046578410.187
positive regulation of gtpase activityGO:0043547280.186
multi organism behaviorGO:00517053890.184
positive regulation of rna metabolic processGO:00512541030.182
Human
carbohydrate derivative metabolic processGO:19011351410.181
determination of adult lifespanGO:00083408120.181
Worm
cell substrate adhesionGO:003158910.180
endocytosisGO:00068978190.180
cell cycle processGO:00224024820.180
Human
regulation of organelle organizationGO:00330431640.179
Human
single organism organelle organizationGO:19025895010.176
Human Mouse
protein localizationGO:00081042050.175
Worm Fly
multi organism reproductive behaviorGO:00447053870.175
multi multicellular organism processGO:00447063900.174
cell projection assemblyGO:0030031350.174
Human
cellular protein localizationGO:0034613750.173
Worm Fly
nucleobase containing compound biosynthetic processGO:00346541840.172
Human
positive regulation of epithelial cell proliferationGO:005067910.172
Human
ribose phosphate metabolic processGO:0019693990.172
cell divisionGO:00513012620.171
neural precursor cell proliferationGO:006135190.170
biosynthetic processGO:00090583230.169
Human
apoptotic processGO:00069154780.167
Mouse Fly
multi organism reproductive processGO:00447038670.166
tube morphogenesisGO:0035239790.165
Mouse Fly
axis specificationGO:0009798230.165
Fly
regulation of canonical wnt signaling pathwayGO:006082810.164
small molecule metabolic processGO:00442811860.163
receptor mediated endocytosisGO:00068987150.160
regulation of transcription from rna polymerase ii promoterGO:00063571450.160
Human
epithelium developmentGO:0060429680.159
Mouse Fly
purine containing compound metabolic processGO:0072521950.159
canonical wnt signaling pathwayGO:006007030.158
regulation of axonogenesisGO:0050770240.155
negative regulation of multicellular organismal processGO:00512412360.155
female gamete generationGO:00072922540.154
tube developmentGO:00352951260.154
Mouse Fly
embryonic morphogenesisGO:00485981520.153
Zebrafish Fly
defense responseGO:00069522960.150
cellular response to fibroblast growth factor stimulusGO:004434450.149
negative regulation of macromolecule metabolic processGO:00106052290.149
Human
regulation of gene expressionGO:00104683660.149
Human Mouse
establishment of organelle localizationGO:00516561230.148
transcription dna templatedGO:00063511680.146
Human
positive regulation of macromolecule metabolic processGO:00106041490.146
Human Mouse
regulation of cell morphogenesis involved in differentiationGO:0010769290.144
tube formationGO:003514820.144
stem cell divisionGO:0017145180.144
cellular component biogenesisGO:00440852970.143
Human
secretionGO:00469031470.143
phosphate containing compound metabolic processGO:00067962320.142
negative regulation of nematode larval developmentGO:00610642080.142
cell adhesionGO:0007155210.141
nucleobase containing small molecule metabolic processGO:00550861150.141
growthGO:00400075620.141
Fly
organonitrogen compound metabolic processGO:19015641510.141
positive regulation of cell projection organizationGO:003134640.140
Human
regulation of cell divisionGO:00513021420.139
nucleoside metabolic processGO:0009116990.138
organophosphate metabolic processGO:00196371250.134
transcription from rna polymerase ii promoterGO:00063661490.132
Human
organelle localizationGO:00516401270.131
positive regulation of phosphate metabolic processGO:0045937560.131
regulation of biological qualityGO:00650087410.131
Mouse Fly
oogenesisGO:00484772290.129
cell deathGO:00082195470.129
Mouse Fly
macromolecule localizationGO:00330367710.128
Worm Fly
regulation of anatomical structure sizeGO:0090066460.126
Fly
single organism catabolic processGO:00447121290.126
cellular localizationGO:00516413600.126
macromolecular complex subunit organizationGO:00439333200.126
digestive system developmentGO:00551231220.124
Fly
cellular response to stressGO:00335541620.123
Human Fly
negative regulation of neurogenesisGO:005076840.123
cellular response to chemical stimulusGO:00708871290.122
epithelial tube morphogenesisGO:006056210.122
Mouse
axon extensionGO:0048675370.121
aromatic compound catabolic processGO:00194391160.119
single organism nuclear importGO:190259360.119
Fly
heterocycle biosynthetic processGO:00181301870.118
Human
organelle fissionGO:00482853630.118
ribonucleoside metabolic processGO:0009119980.117
multicellular organismal agingGO:00102598120.117
Worm
developmental cell growthGO:0048588390.116
Fly
purine ribonucleoside catabolic processGO:0046130750.116
biological adhesionGO:0022610210.115
positive regulation of nucleotide metabolic processGO:0045981280.114
cognitionGO:0050890270.114
Mouse
cellular response to abiotic stimulusGO:007121440.114
dauer larval developmentGO:0040024920.113
purine ribonucleoside triphosphate metabolic processGO:0009205870.113
regulation of cell cycle processGO:00105641450.113
Human
hyperosmotic responseGO:0006972190.112
regulation of neurogenesisGO:0050767400.111
Fly
negative regulation of vulval developmentGO:00400272060.111
cellular component assemblyGO:00226072930.110
Human
developmental growthGO:00485894120.110
Fly
mesodermal cell fate specificationGO:0007501130.107
regulation of neuron projection developmentGO:0010975310.106
cytoskeleton organizationGO:00070103390.105
Human Mouse
nematode male tail tip morphogenesisGO:0045138770.105
molting cycleGO:00423032810.105
negative regulation of response to stimulusGO:0048585730.105
Fly
macromolecule modificationGO:00434122180.104
Human
single organism behaviorGO:0044708830.104
Mouse
purine nucleoside catabolic processGO:0006152750.103
gtp metabolic processGO:0046039460.101
neuron projection extension involved in neuron projection guidanceGO:1902284130.101
phosphorus metabolic processGO:00067932320.100
guanosine containing compound catabolic processGO:1901069480.099
cilium morphogenesisGO:0060271330.099
cellular catabolic processGO:00442481990.098
endodermal cell differentiationGO:0035987180.096
regulation of bmp signaling pathwayGO:003051030.096
oocyte axis specificationGO:000730920.095
Fly
actin filament organizationGO:0007015210.095
regulation of response to stressGO:0080134280.094
Human Fly
muscle organ morphogenesisGO:004864440.092
regulation of nuclear divisionGO:00517831150.092
cellular nitrogen compound catabolic processGO:00442701190.091
nucleoside catabolic processGO:0009164780.090
anatomical structure formation involved in morphogenesisGO:00486462500.090
Fly
axon extension involved in axon guidanceGO:0048846130.090
positive regulation of phosphorus metabolic processGO:0010562560.089
positive regulation of hydrolase activityGO:0051345380.089
cell proliferationGO:00082831160.089
Human Mouse Fly
positive regulation of growthGO:00459273690.088
regulation of gastrulationGO:001047040.088
deathGO:00162655470.088
Mouse Fly
negative regulation of transcription from rna polymerase ii promoterGO:0000122450.087
oocyte constructionGO:000730820.087
Fly
cellular response to hormone stimulusGO:0032870140.085
positive regulation of nucleotide catabolic processGO:0030813280.085
organic substance biosynthetic processGO:19015763230.085
Human
muscle structure developmentGO:00610611910.084
intracellular signal transductionGO:0035556960.083
Human Mouse Fly
cell fate commitment involved in formation of primary germ layerGO:0060795330.083
regulation of catabolic processGO:0009894570.082
regulation of nucleotide metabolic processGO:0006140370.082
regulation of intracellular signal transductionGO:1902531770.082
regulation of cellular component biogenesisGO:0044087260.081
Human
molting cycle collagen and cuticulin based cuticleGO:00189962810.080
regulation of mapk cascadeGO:0043408230.079
Human Fly
cellular protein modification processGO:00064642070.079
Human
protein phosphorylationGO:0006468850.077
Human
negative regulation of transcription dna templatedGO:0045892530.077
regulation of wnt signaling pathwayGO:003011190.075
positive regulation of cell differentiationGO:004559780.075
Fly
establishment or maintenance of cell polarityGO:0007163630.074
Fly
phosphorylationGO:00163101160.073
Human Fly
regulation of localizationGO:00328791940.073
Human Worm
synaptic transmissionGO:00072681060.073
Mouse
negative regulation of developmental processGO:00510932270.073
regulation of phosphorus metabolic processGO:0051174810.072
maintenance of locationGO:00512355800.071
positive regulation of phosphorylationGO:0042327270.071
Human Fly
regulation of apoptotic processGO:0042981360.071
Mouse Fly
cellular macromolecule localizationGO:0070727750.069
Worm Fly
embryonic body morphogenesisGO:0010172490.069
positive regulation of developmental growthGO:00486393540.069
regulation of mesoderm developmentGO:200038020.069
epithelial cell differentiationGO:0030855170.068
Fly
positive regulation of developmental processGO:00510944080.067
macromolecular complex assemblyGO:00650031930.067
mitotic nuclear divisionGO:0007067890.066
regulation of cell proliferationGO:00421271050.066
Human Mouse Fly
bmp signaling pathwayGO:003050930.066
signal transduction by phosphorylationGO:0023014310.066
Human Fly
regulation of hydrolase activityGO:0051336450.064
regulation of nucleotide catabolic processGO:0030811350.064
response to peptide hormoneGO:0043434140.062
lipid storageGO:00199155650.062
regulation of apoptotic signaling pathwayGO:200123310.061
Fly
stem cell proliferationGO:007208990.061
Fly
positive regulation of organ growthGO:004662240.060
purine ribonucleotide metabolic processGO:0009150950.057
neuron projection extensionGO:1990138370.057
organic cyclic compound catabolic processGO:19013611190.057
cell cell signalingGO:00072671180.056
Mouse
cell cycle phase transitionGO:0044770190.056
Human
regulation of growthGO:00400084090.056
Fly
regulation of embryonic developmentGO:0045995160.056
oocyte differentiationGO:0009994450.055
Fly
regulation of programmed cell deathGO:0043067500.055
Mouse Fly
stem cell fate commitmentGO:004886550.055
Fly
intracellular transportGO:0046907770.054
Fly
neuroblast proliferationGO:000740590.054
ovulationGO:0030728330.053
positive regulation of map kinase activityGO:004340690.053
Human
mesoderm developmentGO:0007498270.053
activation of protein kinase activityGO:0032147110.053
specification of axis polarityGO:0065001130.053
cell junction organizationGO:0034330180.053
negative regulation of cellular metabolic processGO:0031324950.053
Human Fly
peptidyl serine modificationGO:0018209200.052
lipid localizationGO:00108765730.052
muscle system processGO:0003012430.052
positive regulation of mapk cascadeGO:0043410140.051
Human Fly
neurological system processGO:0050877530.051
Mouse
positive regulation of multicellular organismal processGO:00512404170.050
organ morphogenesisGO:0009887670.050
Zebrafish Mouse Fly
muscle cell differentiationGO:00426921710.049
Mouse
phagocytosisGO:00069091150.049
protein complex biogenesisGO:00702711860.048
engulfment of apoptotic cellGO:0043652940.048
establishment of protein localization to membraneGO:009015030.047
cell matrix adhesionGO:000716010.047
regulation of cell cell adhesionGO:002240710.047
regulation of sequence specific dna binding transcription factor activityGO:005109030.047
negative regulation of metabolic processGO:00098922400.047
Human Fly
positive regulation of protein metabolic processGO:0051247450.046
Human
regulation of developmental growthGO:00486383890.046
Fly
positive regulation of transferase activityGO:0051347210.046
Human
epithelial cell proliferationGO:005067310.045
Human
positive regulation of protein kinase activityGO:0045860180.045
Human
negative regulation of cell cycleGO:0045786530.045
Human
negative regulation of cellular component organizationGO:0051129330.045
negative regulation of signalingGO:0023057610.045
Fly
actin cytoskeleton organizationGO:00300361840.045
Human Mouse
mitotic cell cycle processGO:19030471940.044
Human
muscle organ developmentGO:0007517260.044
phagocytosis engulfmentGO:0006911980.044
regulation of small gtpase mediated signal transductionGO:0051056410.043
regulation of epithelial cell proliferationGO:005067810.043
Human
regulation of reproductive processGO:2000241660.043
developmental inductionGO:003112810.042
membrane invaginationGO:0010324980.042
apoptotic cell clearanceGO:00432771110.042
extracellular matrix organizationGO:003019860.041
cellular protein complex assemblyGO:00436231780.041
single organism membrane organizationGO:0044802350.041
positive regulation of catabolic processGO:0009896380.041
organic substance transportGO:00717021130.041
Fly
protein complex assemblyGO:00064611860.040
mesodermal cell migrationGO:000807890.040
regulation of axon extensionGO:0030516200.040
negative regulation of macromolecule biosynthetic processGO:0010558650.039
regulation of nervous system developmentGO:0051960410.039
Fly
regulation of nucleocytoplasmic transportGO:004682230.039
somatic stem cell divisionGO:004810390.039
single organism intracellular transportGO:1902582700.038
Fly

let-60 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in worm and predicted with the worm functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.061
cardiovascular system diseaseDOID:128700.061
disease of cellular proliferationDOID:1456600.050
Human
cancerDOID:16200.044
Human