IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

85 known processes

RPM2 (YML091C)

Rpm2p

Entrez: 854883
SGD: S000004556
UniProtKB: Q02773

Process Predictions
Disease Predictions

RPM2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
generation of precursor metabolites and energy	GO:0006091	147	0.773
cellular respiration	GO:0045333	82	0.506
translational initiation	GO:0006413	56	0.397
nucleotide metabolic process	GO:0009117	453	0.364
organophosphate metabolic process	GO:0019637	597	0.354
nucleobase containing small molecule metabolic process	GO:0055086	491	0.334
nucleoside phosphate metabolic process	GO:0006753	458	0.321
aerobic respiration	GO:0009060	55	0.276
ribonucleoside metabolic process	GO:0009119	389	0.275
carbohydrate derivative metabolic process	GO:1901135	549	0.273
phosphorylation	GO:0016310	291	0.263
purine nucleotide metabolic process	GO:0006163	376	0.260
ribonucleotide metabolic process	GO:0009259	377	0.257
oxidation reduction process	GO:0055114	353	0.237
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.233
mitochondrial electron transport ubiquinol to cytochrome c	GO:0006122	11	0.233
mitochondrion organization	GO:0007005	261	0.231
purine containing compound metabolic process	GO:0072521	400	0.228
translation	GO:0006412	230	0.222
glycosyl compound metabolic process	GO:1901657	398	0.217
energy derivation by oxidation of organic compounds	GO:0015980	125	0.213
negative regulation of gene expression	GO:0010629	312	0.198
protein complex assembly	GO:0006461	302	0.197
regulation of biological quality	GO:0065008	391	0.197
inorganic cation transmembrane transport	GO:0098662	98	0.192
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.189
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.188
regulation of molecular function	GO:0065009	320	0.185
purine nucleoside monophosphate metabolic process	GO:0009126	262	0.185
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.182
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.177
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.177
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.169
organic acid metabolic process	GO:0006082	352	0.161
purine ribonucleoside metabolic process	GO:0046128	380	0.160
protein complex biogenesis	GO:0070271	314	0.154
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.152
nucleoside triphosphate metabolic process	GO:0009141	364	0.140
ribose phosphate metabolic process	GO:0019693	384	0.138
purine ribonucleotide metabolic process	GO:0009150	372	0.130
purine ribonucleoside triphosphate biosynthetic process	GO:0009206	17	0.127
regulation of protein metabolic process	GO:0051246	237	0.120
positive regulation of macromolecule metabolic process	GO:0010604	394	0.119
atp metabolic process	GO:0046034	251	0.119
nucleoside monophosphate metabolic process	GO:0009123	267	0.115
nucleoside metabolic process	GO:0009116	394	0.112
carboxylic acid metabolic process	GO:0019752	338	0.109
positive regulation of rna metabolic process	GO:0051254	294	0.101
purine ribonucleotide biosynthetic process	GO:0009152	39	0.096
hydrogen ion transmembrane transport	GO:1902600	49	0.094
organonitrogen compound biosynthetic process	GO:1901566	314	0.094
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.090
oxidative phosphorylation	GO:0006119	26	0.090
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.090
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.090
ribonucleoprotein complex subunit organization	GO:0071826	152	0.087
signaling	GO:0023052	208	0.085
negative regulation of macromolecule metabolic process	GO:0010605	375	0.084
purine nucleotide biosynthetic process	GO:0006164	41	0.083
nucleotide catabolic process	GO:0009166	330	0.082
mitochondrial transport	GO:0006839	76	0.080
single organism catabolic process	GO:0044712	619	0.079
cellular component disassembly	GO:0022411	86	0.078
transmembrane transport	GO:0055085	349	0.077
negative regulation of cellular biosynthetic process	GO:0031327	312	0.077
rna localization	GO:0006403	112	0.076
oxoacid metabolic process	GO:0043436	351	0.074
mitotic cell cycle phase transition	GO:0044772	141	0.074
negative regulation of cellular metabolic process	GO:0031324	407	0.073
organic cyclic compound catabolic process	GO:1901361	499	0.072
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.071
cell communication	GO:0007154	345	0.071
carbohydrate derivative biosynthetic process	GO:1901137	181	0.070
positive regulation of gene expression	GO:0010628	321	0.069
mitochondrion localization	GO:0051646	29	0.069
monosaccharide metabolic process	GO:0005996	83	0.069
purine nucleotide catabolic process	GO:0006195	328	0.067
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.067
gtp metabolic process	GO:0046039	107	0.066
cellular developmental process	GO:0048869	191	0.065
respiratory electron transport chain	GO:0022904	25	0.065
mitochondrial atp synthesis coupled electron transport	GO:0042775	25	0.064
mitochondrial translation	GO:0032543	52	0.063
hydrogen transport	GO:0006818	61	0.062
guanosine containing compound catabolic process	GO:1901069	109	0.062
regulation of catalytic activity	GO:0050790	307	0.062
ribonucleoprotein complex assembly	GO:0022618	143	0.062
mitotic cell cycle	GO:0000278	306	0.061
organelle localization	GO:0051640	128	0.061
atp synthesis coupled electron transport	GO:0042773	25	0.060
purine nucleoside monophosphate biosynthetic process	GO:0009127	28	0.059
cell cycle phase transition	GO:0044770	144	0.058
carbon catabolite regulation of transcription	GO:0045990	39	0.058
negative regulation of transcription dna templated	GO:0045892	258	0.057
nucleobase containing compound transport	GO:0015931	124	0.057
cellular response to dna damage stimulus	GO:0006974	287	0.056
cation transmembrane transport	GO:0098655	135	0.056
purine nucleoside metabolic process	GO:0042278	380	0.056
signal transduction	GO:0007165	208	0.056
nucleoside triphosphate biosynthetic process	GO:0009142	22	0.056
macromolecule catabolic process	GO:0009057	383	0.055
nucleoside biosynthetic process	GO:0009163	38	0.053
single organism carbohydrate metabolic process	GO:0044723	237	0.053
carbohydrate derivative catabolic process	GO:1901136	339	0.052
nucleoside monophosphate biosynthetic process	GO:0009124	33	0.052
carbohydrate metabolic process	GO:0005975	252	0.051
regulation of cellular protein metabolic process	GO:0032268	232	0.051
response to chemical	GO:0042221	390	0.051
purine nucleoside triphosphate biosynthetic process	GO:0009145	17	0.051
cellular protein complex assembly	GO:0043623	209	0.050
inorganic ion transmembrane transport	GO:0098660	109	0.049
hexose metabolic process	GO:0019318	78	0.049
organophosphate biosynthetic process	GO:0090407	182	0.049
posttranscriptional regulation of gene expression	GO:0010608	115	0.047
cellular nitrogen compound catabolic process	GO:0044270	494	0.046
nitrogen compound transport	GO:0071705	212	0.046
proteolysis	GO:0006508	268	0.046
regulation of phosphorus metabolic process	GO:0051174	230	0.045
ion transmembrane transport	GO:0034220	200	0.044
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.043
energy coupled proton transport down electrochemical gradient	GO:0015985	17	0.043
proton transport	GO:0015992	61	0.043
cellular macromolecule catabolic process	GO:0044265	363	0.042
regulation of mitotic cell cycle	GO:0007346	107	0.041
protein transmembrane transport	GO:0071806	82	0.041
nuclear transcribed mrna catabolic process	GO:0000956	89	0.040
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.040
negative regulation of biosynthetic process	GO:0009890	312	0.039
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.039
purine ribonucleoside catabolic process	GO:0046130	330	0.038
nucleotide biosynthetic process	GO:0009165	79	0.038
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.037
protein import	GO:0017038	122	0.037
cytoplasmic translation	GO:0002181	65	0.037
response to external stimulus	GO:0009605	158	0.037
cell fate commitment	GO:0045165	32	0.036
organophosphate catabolic process	GO:0046434	338	0.036
meiotic cell cycle process	GO:1903046	229	0.036
guanosine containing compound metabolic process	GO:1901068	111	0.035
purine ribonucleoside monophosphate biosynthetic process	GO:0009168	28	0.035
heterocycle catabolic process	GO:0046700	494	0.035
nucleoside catabolic process	GO:0009164	335	0.035
proton transporting two sector atpase complex assembly	GO:0070071	15	0.035
meiotic nuclear division	GO:0007126	163	0.035
purine ribonucleotide catabolic process	GO:0009154	327	0.035
ribonucleoside catabolic process	GO:0042454	332	0.034
regulation of translation	GO:0006417	89	0.034
negative regulation of rna biosynthetic process	GO:1902679	260	0.034
ribosome biogenesis	GO:0042254	335	0.034
cell division	GO:0051301	205	0.034
regulation of cellular catabolic process	GO:0031329	195	0.033
mitotic cell cycle process	GO:1903047	294	0.033
gtp catabolic process	GO:0006184	107	0.033
dephosphorylation	GO:0016311	127	0.032
negative regulation of protein metabolic process	GO:0051248	85	0.032
single organism developmental process	GO:0044767	258	0.032
developmental process	GO:0032502	261	0.032
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.032
aromatic compound catabolic process	GO:0019439	491	0.032
establishment of organelle localization	GO:0051656	96	0.032
regulation of signaling	GO:0023051	119	0.031
glycosyl compound catabolic process	GO:1901658	335	0.031
purine nucleoside catabolic process	GO:0006152	330	0.031
regulation of phosphorylation	GO:0042325	86	0.031
positive regulation of rna biosynthetic process	GO:1902680	286	0.031
ion transport	GO:0006811	274	0.031
protein targeting to mitochondrion	GO:0006626	56	0.031
regulation of protein modification process	GO:0031399	110	0.031
negative regulation of rna metabolic process	GO:0051253	262	0.030
positive regulation of transcription dna templated	GO:0045893	286	0.030
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.030
nucleoside phosphate catabolic process	GO:1901292	331	0.030
cellular amino acid metabolic process	GO:0006520	225	0.030
cellular component morphogenesis	GO:0032989	97	0.030
positive regulation of biosynthetic process	GO:0009891	336	0.030
carbohydrate catabolic process	GO:0016052	77	0.030
membrane organization	GO:0061024	276	0.030
golgi vesicle transport	GO:0048193	188	0.029
single organism signaling	GO:0044700	208	0.029
intracellular protein transmembrane import	GO:0044743	67	0.029
carbon catabolite activation of transcription from rna polymerase ii promoter	GO:0000436	22	0.029
cell cycle checkpoint	GO:0000075	82	0.029
purine ribonucleoside biosynthetic process	GO:0046129	31	0.029
carbon catabolite regulation of transcription from rna polymerase ii promoter	GO:0000429	34	0.028
ubiquitin dependent protein catabolic process	GO:0006511	181	0.028
negative regulation of cell division	GO:0051782	66	0.028
alpha amino acid metabolic process	GO:1901605	124	0.028
nicotinamide nucleotide metabolic process	GO:0046496	44	0.027
establishment of protein localization	GO:0045184	367	0.027
ribonucleotide biosynthetic process	GO:0009260	44	0.027
mitochondrial proton transporting atp synthase complex assembly	GO:0033615	11	0.027
dna dependent dna replication	GO:0006261	115	0.026
atp synthesis coupled proton transport	GO:0015986	17	0.026
protein targeting	GO:0006605	272	0.026
positive regulation of cellular catabolic process	GO:0031331	128	0.026
regulation of kinase activity	GO:0043549	71	0.026
cellular response to chemical stimulus	GO:0070887	315	0.026
dna replication	GO:0006260	147	0.026
proton transporting atp synthase complex assembly	GO:0043461	11	0.025
regulation of catabolic process	GO:0009894	199	0.025
organic acid biosynthetic process	GO:0016053	152	0.025
organophosphate ester transport	GO:0015748	45	0.025
nucleoside triphosphate catabolic process	GO:0009143	329	0.025
cellular response to organic substance	GO:0071310	159	0.025
nuclear division	GO:0000280	263	0.025
positive regulation of phosphate metabolic process	GO:0045937	147	0.024
regulation of dna replication	GO:0006275	51	0.024
establishment of protein localization to mitochondrion	GO:0072655	63	0.024
organonitrogen compound catabolic process	GO:1901565	404	0.024
purine containing compound biosynthetic process	GO:0072522	53	0.024
regulation of anatomical structure size	GO:0090066	50	0.024
detection of stimulus	GO:0051606	4	0.024
purine containing compound catabolic process	GO:0072523	332	0.023
regulation of dna dependent dna replication	GO:0090329	37	0.023
alpha amino acid biosynthetic process	GO:1901607	91	0.023
ribonucleoside triphosphate biosynthetic process	GO:0009201	19	0.023
ribose phosphate biosynthetic process	GO:0046390	50	0.023
positive regulation of cell death	GO:0010942	3	0.022
organelle assembly	GO:0070925	118	0.022
single organism cellular localization	GO:1902580	375	0.022
organic hydroxy compound metabolic process	GO:1901615	125	0.022
detection of glucose	GO:0051594	3	0.022
response to organic substance	GO:0010033	182	0.022
nucleoside phosphate biosynthetic process	GO:1901293	80	0.022
cellular amino acid biosynthetic process	GO:0008652	118	0.022
ncrna processing	GO:0034470	330	0.022
reproductive process in single celled organism	GO:0022413	145	0.022
carbon catabolite activation of transcription	GO:0045991	26	0.021
multi organism cellular process	GO:0044764	120	0.021
ribonucleoside monophosphate biosynthetic process	GO:0009156	31	0.021
nadh metabolic process	GO:0006734	12	0.021
regulation of cellular component organization	GO:0051128	334	0.021
regulation of purine nucleotide metabolic process	GO:1900542	109	0.021
positive regulation of apoptotic process	GO:0043065	3	0.021
carboxylic acid biosynthetic process	GO:0046394	152	0.021
intracellular protein transport	GO:0006886	319	0.021
positive regulation of programmed cell death	GO:0043068	3	0.020
single organism membrane organization	GO:0044802	275	0.020
regulation of cyclin dependent protein serine threonine kinase activity	GO:0000079	19	0.020
protein maturation	GO:0051604	76	0.019
glycosyl compound biosynthetic process	GO:1901659	42	0.019
regulation of phosphate metabolic process	GO:0019220	230	0.019
phospholipid metabolic process	GO:0006644	125	0.019
regulation of cell cycle	GO:0051726	195	0.019
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.019
protein catabolic process	GO:0030163	221	0.019
regulation of transferase activity	GO:0051338	83	0.019
purine nucleoside biosynthetic process	GO:0042451	31	0.019
single organism carbohydrate catabolic process	GO:0044724	73	0.019
mitochondrial genome maintenance	GO:0000002	40	0.019
nucleobase containing compound catabolic process	GO:0034655	479	0.018
ribonucleoside biosynthetic process	GO:0042455	37	0.018
negative regulation of cellular component organization	GO:0051129	109	0.018
developmental process involved in reproduction	GO:0003006	159	0.018
positive regulation of molecular function	GO:0044093	185	0.018
metallo sulfur cluster assembly	GO:0031163	22	0.018
establishment of protein localization to organelle	GO:0072594	278	0.018
regulation of cell cycle phase transition	GO:1901987	70	0.018
modification dependent macromolecule catabolic process	GO:0043632	203	0.018
regulation of translational initiation	GO:0006446	18	0.018
negative regulation of cell cycle	GO:0045786	91	0.018
carbohydrate derivative transport	GO:1901264	27	0.018
negative regulation of nuclear division	GO:0051784	62	0.018
positive regulation of protein metabolic process	GO:0051247	93	0.017
positive regulation of secretion	GO:0051047	2	0.017
macromolecular complex disassembly	GO:0032984	80	0.017
regulation of dna metabolic process	GO:0051052	100	0.017
regulation of response to stimulus	GO:0048583	157	0.017
cellular ketone metabolic process	GO:0042180	63	0.017
electron transport chain	GO:0022900	25	0.017
proteasomal protein catabolic process	GO:0010498	141	0.017
regulation of protein kinase activity	GO:0045859	67	0.017
chromatin modification	GO:0016568	200	0.017
atp biosynthetic process	GO:0006754	17	0.016
coenzyme metabolic process	GO:0006732	104	0.016
protein dna complex subunit organization	GO:0071824	153	0.016
regulation of cellular ketone metabolic process	GO:0010565	42	0.016
response to nutrient	GO:0007584	52	0.016
nuclear transcribed mrna catabolic process deadenylation dependent decay	GO:0000288	44	0.016
amine metabolic process	GO:0009308	51	0.016
protein dna complex assembly	GO:0065004	105	0.016
positive regulation of cellular biosynthetic process	GO:0031328	336	0.016
trna metabolic process	GO:0006399	151	0.016
oxidoreduction coenzyme metabolic process	GO:0006733	58	0.016
regulation of nucleoside metabolic process	GO:0009118	106	0.016
positive regulation of catabolic process	GO:0009896	135	0.016
cellular protein catabolic process	GO:0044257	213	0.015
mitochondrial membrane organization	GO:0007006	48	0.015
phospholipid biosynthetic process	GO:0008654	89	0.015
modification dependent protein catabolic process	GO:0019941	181	0.015
multi organism process	GO:0051704	233	0.015
cell differentiation	GO:0030154	161	0.015
nucleic acid transport	GO:0050657	94	0.015
organic anion transport	GO:0015711	114	0.015
spindle assembly	GO:0051225	9	0.015
cellular amine metabolic process	GO:0044106	51	0.015
anatomical structure morphogenesis	GO:0009653	160	0.015
negative regulation of cellular protein metabolic process	GO:0032269	85	0.015
regulation of carbohydrate metabolic process	GO:0006109	43	0.014
inner mitochondrial membrane organization	GO:0007007	26	0.014
negative regulation of catabolic process	GO:0009895	43	0.014
chromatin remodeling	GO:0006338	80	0.014
rrna processing	GO:0006364	227	0.014
regulation of nucleotide metabolic process	GO:0006140	110	0.014
lipid metabolic process	GO:0006629	269	0.014
positive regulation of phosphorus metabolic process	GO:0010562	147	0.014
establishment of rna localization	GO:0051236	92	0.014
positive regulation of secretion by cell	GO:1903532	2	0.013
cellular response to nutrient	GO:0031670	50	0.013
pyridine containing compound metabolic process	GO:0072524	53	0.013
cell cycle g2 m phase transition	GO:0044839	39	0.013
maintenance of location in cell	GO:0051651	58	0.013
anatomical structure development	GO:0048856	160	0.013
regulation of dna templated transcription in response to stress	GO:0043620	51	0.013
ribonucleotide catabolic process	GO:0009261	327	0.013
ribonucleoside monophosphate catabolic process	GO:0009158	224	0.013
positive regulation of intracellular transport	GO:0032388	4	0.013
protein processing	GO:0016485	64	0.013
anion transport	GO:0006820	145	0.013
rna transport	GO:0050658	92	0.013
lipid biosynthetic process	GO:0008610	170	0.013
regulation of cell size	GO:0008361	30	0.013
regulation of nuclear division	GO:0051783	103	0.013
nad metabolic process	GO:0019674	25	0.013
regulation of organelle organization	GO:0033043	243	0.013
cytoskeleton organization	GO:0007010	230	0.013
meiotic cell cycle	GO:0051321	272	0.013
negative regulation of proteolysis	GO:0045861	33	0.013
cellular carbohydrate metabolic process	GO:0044262	135	0.012
chromatin silencing	GO:0006342	147	0.012
organelle inheritance	GO:0048308	51	0.012
microtubule cytoskeleton organization	GO:0000226	109	0.012
regulation of signal transduction	GO:0009966	114	0.012
regulation of cellular amine metabolic process	GO:0033238	21	0.012
conjugation with cellular fusion	GO:0000747	106	0.012
regulation of cell division	GO:0051302	113	0.012
response to inorganic substance	GO:0010035	47	0.012
actin cytoskeleton organization	GO:0030036	100	0.012
negative regulation of organelle organization	GO:0010639	103	0.012
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.012
regulation of cellular carbohydrate metabolic process	GO:0010675	41	0.012
positive regulation of protein modification process	GO:0031401	49	0.012
rna modification	GO:0009451	99	0.012
response to extracellular stimulus	GO:0009991	156	0.012
trna processing	GO:0008033	101	0.012
cellular lipid metabolic process	GO:0044255	229	0.012
misfolded or incompletely synthesized protein catabolic process	GO:0006515	21	0.012
regulation of cellular component size	GO:0032535	50	0.012
regulation of glucose metabolic process	GO:0010906	27	0.012
positive regulation of cell cycle	GO:0045787	32	0.011
positive regulation of cellular component organization	GO:0051130	116	0.011
mitotic nuclear division	GO:0007067	131	0.011
cellular response to extracellular stimulus	GO:0031668	150	0.011
g2 m transition of mitotic cell cycle	GO:0000086	38	0.011
acetate biosynthetic process	GO:0019413	4	0.011
chromatin organization	GO:0006325	242	0.011
monocarboxylic acid metabolic process	GO:0032787	122	0.011
nuclear export	GO:0051168	124	0.011
negative regulation of cell cycle process	GO:0010948	86	0.011
regulation of hydrolase activity	GO:0051336	133	0.011
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.010
pyruvate metabolic process	GO:0006090	37	0.010
hexose biosynthetic process	GO:0019319	30	0.010
regulation of transmembrane transporter activity	GO:0022898	1	0.010
small molecule biosynthetic process	GO:0044283	258	0.010
cell surface receptor signaling pathway	GO:0007166	38	0.010
autophagy	GO:0006914	106	0.010
pyridine nucleotide metabolic process	GO:0019362	45	0.010
regulation of cellular amino acid metabolic process	GO:0006521	16	0.010
purine ribonucleoside monophosphate catabolic process	GO:0009169	224	0.010
mrna catabolic process	GO:0006402	93	0.010

RPM2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease	DO term ID	Probability
cancer	DOID:162	0.013
organ system cancer	DOID:0050686	0.013
disease of cellular proliferation	DOID:14566	0.013
disease of anatomical entity	DOID:7	0.011

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