Saccharomyces cerevisiae

105 known processes

MLH1 (YMR167W)

Mlh1p

(Aliases: PMS2)

MLH1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiosis iGO:0007127920.997
meiotic cell cycle processGO:19030462290.994
dna recombinationGO:00063101720.989
dna repairGO:00062812360.983
meiotic nuclear divisionGO:00071261630.981
nuclear divisionGO:00002802630.956
cellular response to dna damage stimulusGO:00069742870.941
reciprocal meiotic recombinationGO:0007131540.937
organelle fissionGO:00482852720.914
meiotic cell cycleGO:00513212720.769
reciprocal dna recombinationGO:0035825540.426
macromolecule catabolic processGO:00090573830.375
Mouse
cellular macromolecule catabolic processGO:00442653630.314
Mouse
negative regulation of nucleobase containing compound metabolic processGO:00459342950.297
Mouse
negative regulation of cellular metabolic processGO:00313244070.256
Mouse
developmental process involved in reproductionGO:00030061590.246
Mouse
negative regulation of nitrogen compound metabolic processGO:00511723000.241
Mouse
mismatch repairGO:0006298140.236
nucleic acid phosphodiester bond hydrolysisGO:00903051940.218
mitotic recombinationGO:0006312550.193
Mouse
reproductive process in single celled organismGO:00224131450.184
cell fate commitmentGO:0045165320.178
dna catabolic processGO:0006308420.174
regulation of dna metabolic processGO:00510521000.172
Mouse
heterocycle catabolic processGO:00467004940.163
aromatic compound catabolic processGO:00194394910.162
organic cyclic compound catabolic processGO:19013614990.149
nucleobase containing compound catabolic processGO:00346554790.145
meiotic mismatch repairGO:000071090.143
single organism developmental processGO:00447672580.142
Mouse
protein complex biogenesisGO:00702713140.133
Mouse
chromosome segregationGO:00070591590.124
Zebrafish Mouse
mating type determinationGO:0007531320.122
reproduction of a single celled organismGO:00325051910.113
organic acid metabolic processGO:00060823520.112
positive regulation of nucleobase containing compound metabolic processGO:00459354090.111
negative regulation of macromolecule biosynthetic processGO:00105582910.106
cellular nitrogen compound catabolic processGO:00442704940.102
cytoskeleton organizationGO:00070102300.094
Mouse
positive regulation of macromolecule metabolic processGO:00106043940.092
regulation of cell cycleGO:00517261950.092
response to chemicalGO:00422213900.089
non recombinational repairGO:0000726330.088
Mouse
mitotic cell cycle processGO:19030472940.085
chromosome organization involved in meiosisGO:0070192320.084
Zebrafish Mouse
mitotic cell cycleGO:00002783060.084
positive regulation of rna biosynthetic processGO:19026802860.083
cellular developmental processGO:00488691910.082
Mouse
gene silencingGO:00164581510.080
single organism catabolic processGO:00447126190.076
developmental processGO:00325022610.074
Mouse
regulation of biological qualityGO:00650083910.071
homeostatic processGO:00425922270.068
mitotic cell cycle phase transitionGO:00447721410.068
positive regulation of transcription dna templatedGO:00458932860.068
positive regulation of macromolecule biosynthetic processGO:00105573250.066
mating type switchingGO:0007533280.064
regulation of mitotic cell cycle phase transitionGO:1901990680.060
regulation of transcription from rna polymerase ii promoterGO:00063573940.060
regulation of protein metabolic processGO:00512462370.059
negative regulation of cellular biosynthetic processGO:00313273120.059
negative regulation of biosynthetic processGO:00098903120.057
positive regulation of gene expressionGO:00106283210.055
single organism reproductive processGO:00447021590.054
Zebrafish Mouse
ribonucleoside metabolic processGO:00091193890.054
negative regulation of gene expressionGO:00106293120.052
chromatin organizationGO:00063252420.051
positive regulation of nitrogen compound metabolic processGO:00511734120.051
carbohydrate derivative metabolic processGO:19011355490.049
nucleoside phosphate metabolic processGO:00067534580.049
regulation of cellular component organizationGO:00511283340.048
protein catabolic processGO:00301632210.048
protein complex assemblyGO:00064613020.047
Mouse
cell differentiationGO:00301541610.047
Mouse
positive regulation of nucleic acid templated transcriptionGO:19035082860.047
negative regulation of transcription dna templatedGO:00458922580.045
lipid metabolic processGO:00066292690.045
regulation of molecular functionGO:00650093200.045
negative regulation of macromolecule metabolic processGO:00106053750.045
Mouse
nucleobase containing small molecule metabolic processGO:00550864910.045
regulation of nuclear divisionGO:00517831030.045
gene conversionGO:0035822140.044
anatomical structure morphogenesisGO:00096531600.044
reproductive processGO:00224142480.043
Zebrafish Mouse
anion transportGO:00068201450.043
regulation of dna recombinationGO:0000018240.043
Mouse
negative regulation of rna metabolic processGO:00512532620.043
double strand break repairGO:00063021050.043
Mouse
chemical homeostasisGO:00488781370.042
mitotic nuclear divisionGO:00070671310.041
organonitrogen compound biosynthetic processGO:19015663140.040
negative regulation of mitotic cell cycle phase transitionGO:1901991570.040
negative regulation of cellular macromolecule biosynthetic processGO:20001132890.037
cellular lipid metabolic processGO:00442552290.037
positive regulation of biosynthetic processGO:00098913360.037
cell cycle phase transitionGO:00447701440.037
positive regulation of transcription from rna polymerase ii promoterGO:00459442520.036
cellular protein complex assemblyGO:00436232090.036
Mouse
regulation of response to stimulusGO:00485831570.036
microtubule cytoskeleton organizationGO:00002261090.035
Mouse
regulation of gene expression epigeneticGO:00400291470.035
mitochondrion organizationGO:00070052610.035
meiotic chromosome segregationGO:0045132310.035
Zebrafish Mouse
microtubule based processGO:00070171170.034
Mouse
organic anion transportGO:00157111140.034
negative regulation of dna metabolic processGO:0051053360.033
Mouse
negative regulation of nucleic acid templated transcriptionGO:19035072600.033
nucleobase containing compound transportGO:00159311240.033
regulation of mitotic cell cycleGO:00073461070.033
response to abiotic stimulusGO:00096281590.032
mitochondrial genome maintenanceGO:0000002400.031
purine ribonucleoside metabolic processGO:00461283800.031
regulation of organelle organizationGO:00330432430.030
positive regulation of rna metabolic processGO:00512542940.030
filamentous growthGO:00304471240.030
sporulationGO:00439341320.030
regulation of catabolic processGO:00098941990.030
negative regulation of cell cycle phase transitionGO:1901988590.030
cell communicationGO:00071543450.030
Mouse
positive regulation of cellular biosynthetic processGO:00313283360.030
modification dependent macromolecule catabolic processGO:00436322030.029
sex determinationGO:0007530320.028
regulation of cellular catabolic processGO:00313291950.028
regulation of cell cycle phase transitionGO:1901987700.027
organelle assemblyGO:00709251180.026
Mouse
ribose phosphate metabolic processGO:00196933840.026
organophosphate metabolic processGO:00196375970.026
nucleoside catabolic processGO:00091643350.026
mitotic cell cycle checkpointGO:0007093560.026
glycosyl compound catabolic processGO:19016583350.026
chromatin modificationGO:00165682000.026
regulation of signalingGO:00230511190.025
rna localizationGO:00064031120.025
protein modification by small protein conjugation or removalGO:00706471720.025
nucleotide excision repairGO:0006289500.025
negative regulation of transcription from rna polymerase ii promoterGO:00001221370.025
purine nucleoside monophosphate metabolic processGO:00091262620.025
fatty acid metabolic processGO:0006631510.025
cell agingGO:0007569700.024
phosphorylationGO:00163102910.024
regulation of response to stressGO:0080134570.024
response to external stimulusGO:00096051580.023
positive regulation of hydrolase activityGO:00513451120.023
response to nutrient levelsGO:00316671500.023
cellular response to chemical stimulusGO:00708873150.023
energy derivation by oxidation of organic compoundsGO:00159801250.023
positive regulation of molecular functionGO:00440931850.023
protein importGO:00170381220.023
single organism cellular localizationGO:19025803750.022
lipid biosynthetic processGO:00086101700.022
nitrogen compound transportGO:00717052120.022
rna catabolic processGO:00064011180.022
Mouse
ribonucleoside catabolic processGO:00424543320.021
chromatin silencingGO:00063421470.021
regulation of cellular protein metabolic processGO:00322682320.021
purine ribonucleotide catabolic processGO:00091543270.021
carboxylic acid biosynthetic processGO:00463941520.021
oxoacid metabolic processGO:00434363510.021
oxidation reduction processGO:00551143530.021
double strand break repair via single strand annealingGO:004500270.020
removal of nonhomologous endsGO:000073560.020
nuclear transportGO:00511691650.020
g1 s transition of mitotic cell cycleGO:0000082640.020
regulation of localizationGO:00328791270.020
cell developmentGO:00484681070.020
Mouse
chromatin silencing at silent mating type cassetteGO:0030466530.020
regulation of translationGO:0006417890.020
mrna metabolic processGO:00160712690.019
Mouse
cellular response to abiotic stimulusGO:0071214620.019
apoptotic processGO:0006915300.019
Mouse
regulation of meiosisGO:0040020420.019
ribonucleoside triphosphate catabolic processGO:00092033270.019
nucleotide metabolic processGO:00091174530.019
maintenance of location in cellGO:0051651580.019
cellular response to organic substanceGO:00713101590.019
cellular ion homeostasisGO:00068731120.019
carboxylic acid metabolic processGO:00197523380.019
negative regulation of rna biosynthetic processGO:19026792600.018
negative regulation of cellular protein metabolic processGO:0032269850.018
sexual reproductionGO:00199532160.018
Zebrafish Mouse
ion homeostasisGO:00508011180.018
histone modificationGO:00165701190.018
regulation of cell cycle processGO:00105641500.018
glycosyl compound metabolic processGO:19016573980.017
protein transportGO:00150313450.017
sister chromatid segregationGO:0000819930.017
synapsisGO:0007129190.017
Zebrafish Mouse
regulation of hydrolase activityGO:00513361330.017
organelle localizationGO:00516401280.017
Zebrafish Mouse
purine ribonucleoside triphosphate catabolic processGO:00092073270.016
purine nucleoside catabolic processGO:00061523300.016
cell divisionGO:00513012050.016
signalingGO:00230522080.016
Mouse
organonitrogen compound catabolic processGO:19015654040.016
dna conformation changeGO:0071103980.016
agingGO:0007568710.016
positive regulation of cellular catabolic processGO:00313311280.016
negative regulation of gene expression epigeneticGO:00458141470.016
programmed cell deathGO:0012501300.015
Mouse
positive regulation of cell cycleGO:0045787320.015
purine nucleoside monophosphate catabolic processGO:00091282240.015
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611370.015
purine ribonucleotide metabolic processGO:00091503720.015
response to organic cyclic compoundGO:001407010.015
purine containing compound metabolic processGO:00725214000.015
double strand break repair via synthesis dependent strand annealingGO:0045003120.014
cellular response to external stimulusGO:00714961500.014
positive regulation of catalytic activityGO:00430851780.014
mitotic dna integrity checkpointGO:0044774180.014
purine containing compound catabolic processGO:00725233320.014
regulation of dna replicationGO:0006275510.014
cellular response to oxidative stressGO:0034599940.014
gene conversion at mating type locusGO:0007534110.014
response to drugGO:0042493410.014
regulation of transportGO:0051049850.014
nucleoside phosphate catabolic processGO:19012923310.014
growthGO:00400071570.014
ribonucleoside triphosphate metabolic processGO:00091993560.013
anatomical structure developmentGO:00488561600.013
Mouse
amine metabolic processGO:0009308510.013
intracellular signal transductionGO:00355561120.013
Mouse
sexual sporulation resulting in formation of a cellular sporeGO:00439351130.013
membrane organizationGO:00610242760.013
cellular homeostasisGO:00197251380.013
nucleoside monophosphate catabolic processGO:00091252240.013
proteolysisGO:00065082680.013
double strand break repair via homologous recombinationGO:0000724540.013
nucleoside metabolic processGO:00091163940.013
deathGO:0016265300.013
Mouse
purine nucleoside triphosphate catabolic processGO:00091463290.013
actin cytoskeleton organizationGO:00300361000.013
cellular respirationGO:0045333820.013
proteasomal protein catabolic processGO:00104981410.013
mitotic sister chromatid segregationGO:0000070850.013
regulation of response to external stimulusGO:0032101200.012
proteolysis involved in cellular protein catabolic processGO:00516031980.012
establishment of protein localization to mitochondrionGO:0072655630.012
multi organism processGO:00517042330.012
Zebrafish Mouse
positive regulation of protein metabolic processGO:0051247930.012
dna packagingGO:0006323550.012
mrna export from nucleusGO:0006406600.012
cellular chemical homeostasisGO:00550821230.012
ribonucleoside monophosphate catabolic processGO:00091582240.012
response to extracellular stimulusGO:00099911560.012
mitochondrion localizationGO:0051646290.012
positive regulation of cell cycle processGO:0090068310.012
translationGO:00064122300.012
cell growthGO:0016049890.012
pseudohyphal growthGO:0007124750.012
ribonucleoside monophosphate metabolic processGO:00091612650.012
organic acid catabolic processGO:0016054710.012
regulation of growthGO:0040008500.012
mitotic cytokinesisGO:0000281580.012
single organism signalingGO:00447002080.012
Mouse
nucleoside triphosphate metabolic processGO:00091413640.012
protein dna complex subunit organizationGO:00718241530.012
regulation of cell divisionGO:00513021130.011
response to oxidative stressGO:0006979990.011
ribonucleotide catabolic processGO:00092613270.011
positive regulation of catabolic processGO:00098961350.011
rna splicingGO:00083801310.011
cellular amine metabolic processGO:0044106510.011
regulation of catalytic activityGO:00507903070.011
single organism membrane organizationGO:00448022750.011
filamentous growth of a population of unicellular organismsGO:00441821090.011
regulation of protein localizationGO:0032880620.011
protein ubiquitinationGO:00165671180.011
posttranscriptional regulation of gene expressionGO:00106081150.011
establishment of protein localization to membraneGO:0090150990.011
regulation of phosphorus metabolic processGO:00511742300.011
negative regulation of mitotic cell cycleGO:0045930630.011
macromolecular complex disassemblyGO:0032984800.011
carbohydrate derivative catabolic processGO:19011363390.011
small molecule biosynthetic processGO:00442832580.011
regulation of signal transductionGO:00099661140.011
negative regulation of cellular component organizationGO:00511291090.011
protein modification by small protein conjugationGO:00324461440.010
maintenance of protein locationGO:0045185530.010
response to uvGO:000941140.010
response to oxygen containing compoundGO:1901700610.010
aerobic respirationGO:0009060550.010
nucleotide catabolic processGO:00091663300.010
purine ribonucleoside triphosphate metabolic processGO:00092053540.010
regulation of response to nutrient levelsGO:0032107200.010
nucleic acid transportGO:0050657940.010
cellular component disassemblyGO:0022411860.010
purine nucleoside metabolic processGO:00422783800.010

MLH1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org