| proteolysis | GO:0006508 | 268 | 0.731 | |
| single organism cellular localization | GO:1902580 | 375 | 0.714 | |
| mitotic cell cycle process | GO:1903047 | 294 | 0.542 | |
| cell surface receptor signaling pathway | GO:0007166 | 38 | 0.511 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 181 | 0.466 | |
| protein complex biogenesis | GO:0070271 | 314 | 0.458 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 203 | 0.439 | |
| membrane organization | GO:0061024 | 276 | 0.409 | |
| actin filament organization | GO:0007015 | 56 | 0.407 | |
| single organism membrane organization | GO:0044802 | 275 | 0.405 | |
| proteasomal protein catabolic process | GO:0010498 | 141 | 0.377 | |
| cell communication | GO:0007154 | 345 | 0.368 | |
| protein targeting | GO:0006605 | 272 | 0.322 | |
| regulation of protein catabolic process | GO:0042176 | 40 | 0.321 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 375 | 0.316 | |
| modification dependent protein catabolic process | GO:0019941 | 181 | 0.303 | |
| endocytosis | GO:0006897 | 90 | 0.271 | |
| mitotic cell cycle | GO:0000278 | 306 | 0.269 | |
| negative regulation of biosynthetic process | GO:0009890 | 312 | 0.263 | |
| cellular protein complex assembly | GO:0043623 | 209 | 0.247 | |
| regulation of proteolysis | GO:0030162 | 44 | 0.214 | |
| regulation of organelle organization | GO:0033043 | 243 | 0.198 | |
| single organism catabolic process | GO:0044712 | 619 | 0.195 | |
| protein polymerization | GO:0051258 | 51 | 0.193 | |
| negative regulation of gene expression | GO:0010629 | 312 | 0.188 | |
| cytoskeleton organization | GO:0007010 | 230 | 0.179 | |
| cellular protein catabolic process | GO:0044257 | 213 | 0.175 | |
| actin filament based process | GO:0030029 | 104 | 0.172 | |
| microtubule based process | GO:0007017 | 117 | 0.170 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 34 | 0.168 | |
| protein transport | GO:0015031 | 345 | 0.166 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 336 | 0.151 | |
| establishment of protein localization | GO:0045184 | 367 | 0.145 | |
| regulation of response to stress | GO:0080134 | 57 | 0.137 | |
| regulation of catabolic process | GO:0009894 | 199 | 0.132 | |
| regulation of dna metabolic process | GO:0051052 | 100 | 0.131 | |
| positive regulation of biosynthetic process | GO:0009891 | 336 | 0.124 | |
| regulation of cellular component organization | GO:0051128 | 334 | 0.124 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 260 | 0.117 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 325 | 0.115 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 260 | 0.114 | |
| regulation of cellular protein catabolic process | GO:1903362 | 36 | 0.114 | |
| single organism signaling | GO:0044700 | 208 | 0.113 | |
| protein import into nucleus | GO:0006606 | 55 | 0.112 | |
| intracellular protein transport | GO:0006886 | 319 | 0.107 | |
| regulation of actin filament based process | GO:0032970 | 31 | 0.105 | |
| signal transduction | GO:0007165 | 208 | 0.105 | |
| vesicle mediated transport | GO:0016192 | 335 | 0.105 | |
| signaling | GO:0023052 | 208 | 0.095 | |
| response to organic substance | GO:0010033 | 182 | 0.095 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 198 | 0.094 | |
| regulation of cell cycle | GO:0051726 | 195 | 0.093 | |
| protein complex assembly | GO:0006461 | 302 | 0.090 | |
| protein catabolic process | GO:0030163 | 221 | 0.088 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 312 | 0.087 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 409 | 0.081 | |
| cell differentiation | GO:0030154 | 161 | 0.079 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 36 | 0.077 | |
| protein localization to organelle | GO:0033365 | 337 | 0.074 | |
| macromolecule catabolic process | GO:0009057 | 383 | 0.072 | |
| small gtpase mediated signal transduction | GO:0007264 | 36 | 0.072 | |
| oxoacid metabolic process | GO:0043436 | 351 | 0.071 | |
| negative regulation of rna metabolic process | GO:0051253 | 262 | 0.069 | |
| cellular macromolecule catabolic process | GO:0044265 | 363 | 0.068 | |
| response to chemical | GO:0042221 | 390 | 0.067 | |
| regulation of biological quality | GO:0065008 | 391 | 0.061 | |
| cellular response to chemical stimulus | GO:0070887 | 315 | 0.061 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 115 | 0.058 | |
| cellular amino acid metabolic process | GO:0006520 | 225 | 0.057 | |
| positive regulation of gene expression | GO:0010628 | 321 | 0.054 | |
| positive regulation of catabolic process | GO:0009896 | 135 | 0.052 | |
| regulation of cellular catabolic process | GO:0031329 | 195 | 0.051 | |
| regulation of protein metabolic process | GO:0051246 | 237 | 0.051 | |
| endomembrane system organization | GO:0010256 | 74 | 0.050 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 291 | 0.046 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 289 | 0.045 | |
| cell division | GO:0051301 | 205 | 0.044 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 356 | 0.043 | |
| regulation of response to stimulus | GO:0048583 | 157 | 0.042 | |
| nuclear import | GO:0051170 | 57 | 0.042 | |
| response to oxidative stress | GO:0006979 | 99 | 0.042 | |
| developmental process | GO:0032502 | 261 | 0.041 | |
| histone modification | GO:0016570 | 119 | 0.040 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 300 | 0.039 | |
| regulation of protein polymerization | GO:0032271 | 33 | 0.038 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 394 | 0.038 | |
| protein localization to nucleus | GO:0034504 | 74 | 0.038 | |
| establishment of protein localization to organelle | GO:0072594 | 278 | 0.037 | |
| carbohydrate derivative metabolic process | GO:1901135 | 549 | 0.037 | |
| positive regulation of signaling | GO:0023056 | 20 | 0.036 | |
| cellular response to endogenous stimulus | GO:0071495 | 22 | 0.036 | |
| regulation of dna replication | GO:0006275 | 51 | 0.036 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 295 | 0.036 | |
| translation | GO:0006412 | 230 | 0.035 | |
| negative regulation of cellular metabolic process | GO:0031324 | 407 | 0.035 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 329 | 0.035 | |
| nucleoside metabolic process | GO:0009116 | 394 | 0.034 | |
| purine ribonucleoside metabolic process | GO:0046128 | 380 | 0.033 | |
| response to endogenous stimulus | GO:0009719 | 26 | 0.032 | |
| ribonucleotide catabolic process | GO:0009261 | 327 | 0.031 | |
| negative regulation of transcription dna templated | GO:0045892 | 258 | 0.031 | |
| peptidyl amino acid modification | GO:0018193 | 116 | 0.031 | |
| purine nucleoside metabolic process | GO:0042278 | 380 | 0.031 | |
| carbohydrate derivative catabolic process | GO:1901136 | 339 | 0.031 | |
| cellular component movement | GO:0006928 | 20 | 0.031 | |
| dna replication | GO:0006260 | 147 | 0.031 | |
| positive regulation of protein metabolic process | GO:0051247 | 93 | 0.030 | |
| purine ribonucleotide metabolic process | GO:0009150 | 372 | 0.030 | |
| positive regulation of cellular catabolic process | GO:0031331 | 128 | 0.029 | |
| single organism developmental process | GO:0044767 | 258 | 0.028 | |
| anatomical structure morphogenesis | GO:0009653 | 160 | 0.028 | |
| regulation of signaling | GO:0023051 | 119 | 0.028 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 16 | 0.027 | |
| regulation of cellular protein metabolic process | GO:0032268 | 232 | 0.027 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 329 | 0.026 | |
| regulation of intracellular signal transduction | GO:1902531 | 78 | 0.025 | |
| multi organism process | GO:0051704 | 233 | 0.025 | |
| positive regulation of cell communication | GO:0010647 | 28 | 0.024 | |
| organonitrogen compound catabolic process | GO:1901565 | 404 | 0.024 | |
| purine ribonucleoside catabolic process | GO:0046130 | 330 | 0.023 | |
| endosome organization | GO:0007032 | 9 | 0.023 | |
| cellular protein complex disassembly | GO:0043624 | 42 | 0.023 | |
| ribonucleoside metabolic process | GO:0009119 | 389 | 0.022 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 286 | 0.022 | |
| regulation of actin cytoskeleton organization | GO:0032956 | 31 | 0.022 | |
| trna metabolic process | GO:0006399 | 151 | 0.022 | |
| regulation of localization | GO:0032879 | 127 | 0.021 | |
| response to biotic stimulus | GO:0009607 | 8 | 0.021 | |
| regulation of actin polymerization or depolymerization | GO:0008064 | 19 | 0.020 | |
| regulation of cell communication | GO:0010646 | 124 | 0.019 | |
| glycosyl compound catabolic process | GO:1901658 | 335 | 0.019 | |
| negative regulation of cellular component organization | GO:0051129 | 109 | 0.019 | |
| protein import | GO:0017038 | 122 | 0.019 | |
| regulation of ras gtpase activity | GO:0032318 | 41 | 0.019 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 412 | 0.019 | |
| regulation of anatomical structure size | GO:0090066 | 50 | 0.019 | |
| ribonucleoside catabolic process | GO:0042454 | 332 | 0.018 | |
| regulation of actin filament polymerization | GO:0030833 | 19 | 0.017 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 172 | 0.017 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 394 | 0.017 | |
| cell cycle phase transition | GO:0044770 | 144 | 0.017 | |
| response to organic cyclic compound | GO:0014070 | 1 | 0.017 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 137 | 0.017 | |
| positive regulation of organelle organization | GO:0010638 | 85 | 0.016 | |
| nucleoside phosphate catabolic process | GO:1901292 | 331 | 0.016 | |
| purine ribonucleotide catabolic process | GO:0009154 | 327 | 0.016 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.016 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 327 | 0.015 | |
| organophosphate catabolic process | GO:0046434 | 338 | 0.015 | |
| purine containing compound metabolic process | GO:0072521 | 400 | 0.015 | |
| purine containing compound catabolic process | GO:0072523 | 332 | 0.015 | |
| single organism membrane budding | GO:1902591 | 21 | 0.014 | |
| cytokinesis | GO:0000910 | 92 | 0.014 | |
| regulation of nucleotide metabolic process | GO:0006140 | 110 | 0.014 | |
| positive regulation of apoptotic process | GO:0043065 | 3 | 0.014 | |
| cell budding | GO:0007114 | 48 | 0.014 | |
| positive regulation of response to stimulus | GO:0048584 | 37 | 0.014 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 224 | 0.014 | |
| regulation of actin filament length | GO:0030832 | 19 | 0.014 | |
| positive regulation of programmed cell death | GO:0043068 | 3 | 0.014 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 109 | 0.013 | |
| actin polymerization or depolymerization | GO:0008154 | 17 | 0.013 | |
| negative regulation of intracellular signal transduction | GO:1902532 | 27 | 0.013 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 286 | 0.013 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 224 | 0.013 | |
| organelle fission | GO:0048285 | 272 | 0.013 | |
| regulation of protein complex assembly | GO:0043254 | 77 | 0.013 | |
| purine nucleoside catabolic process | GO:0006152 | 330 | 0.012 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 356 | 0.012 | |
| protein depolymerization | GO:0051261 | 21 | 0.012 | |
| nucleobase containing compound catabolic process | GO:0034655 | 479 | 0.012 | |
| cellular developmental process | GO:0048869 | 191 | 0.012 | |
| actin filament bundle organization | GO:0061572 | 19 | 0.011 | |
| amine metabolic process | GO:0009308 | 51 | 0.011 | |
| organophosphate metabolic process | GO:0019637 | 597 | 0.011 | |
| protein targeting to nucleus | GO:0044744 | 57 | 0.011 | |
| heterocycle catabolic process | GO:0046700 | 494 | 0.011 | |
| organic cyclic compound catabolic process | GO:1901361 | 499 | 0.011 | |
| actin filament bundle assembly | GO:0051017 | 19 | 0.011 | |
| regulation of molecular function | GO:0065009 | 320 | 0.011 | |
| regulation of signal transduction | GO:0009966 | 114 | 0.011 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 224 | 0.010 | |
| actin filament polymerization | GO:0030041 | 16 | 0.010 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.010 | |
| positive regulation of cell death | GO:0010942 | 3 | 0.010 | |
| regulation of protein localization | GO:0032880 | 62 | 0.010 | |