IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

11 known processes

CCT2 (YIL142W)

Cct2p

(Aliases: TCP2,BIN3)

SGD: S000001404
Entrez: 854664
UniProtKB: P39076

Process Predictions
Disease Predictions

CCT2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
spindle assembly	GO:0051225	9	0.963	Fly
protein folding	GO:0006457	94	0.942
organelle fission	GO:0048285	272	0.918	Fly
mitotic nuclear division	GO:0007067	131	0.889	Fly
mitotic cell cycle	GO:0000278	306	0.812	Fly
nuclear division	GO:0000280	263	0.783	Fly
spindle organization	GO:0007051	37	0.780	Fly
sexual reproduction	GO:0019953	216	0.702	Mouse
microtubule cytoskeleton organization involved in mitosis	GO:1902850	13	0.688	Fly
meiotic cell cycle process	GO:1903046	229	0.662
single organism reproductive process	GO:0044702	159	0.644	Mouse
multi organism reproductive process	GO:0044703	216	0.629	Mouse
mitotic cell cycle process	GO:1903047	294	0.602	Fly
mitotic spindle organization	GO:0007052	30	0.575	Fly
microtubule based process	GO:0007017	117	0.506	Fly
microtubule cytoskeleton organization	GO:0000226	109	0.493	Fly
meiotic nuclear division	GO:0007126	163	0.448
positive regulation of rna biosynthetic process	GO:1902680	286	0.445
regulation of meiosis	GO:0040020	42	0.443
meiosis i	GO:0007127	92	0.435
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.422
protein complex assembly	GO:0006461	302	0.411	Human Fly
protein complex biogenesis	GO:0070271	314	0.405	Human Fly
regulation of meiotic cell cycle	GO:0051445	43	0.326
organelle assembly	GO:0070925	118	0.318	Fly
positive regulation of macromolecule metabolic process	GO:0010604	394	0.308
multi organism process	GO:0051704	233	0.305	Mouse
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.302
spindle assembly involved in mitosis	GO:0090307	4	0.283	Fly
positive regulation of gene expression	GO:0010628	321	0.267
regulation of cell cycle process	GO:0010564	150	0.254
negative regulation of nuclear division	GO:0051784	62	0.245
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.234
reproductive process	GO:0022414	248	0.213	Mouse
positive regulation of transcription dna templated	GO:0045893	286	0.211
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.201
cytoskeleton organization	GO:0007010	230	0.195	Fly
cellular amino acid biosynthetic process	GO:0008652	118	0.183
positive regulation of biosynthetic process	GO:0009891	336	0.180
signaling	GO:0023052	208	0.169
meiotic cell cycle	GO:0051321	272	0.164
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.163
fungal type cell wall organization or biogenesis	GO:0071852	169	0.154
negative regulation of meiotic cell cycle	GO:0051447	24	0.135
cell communication	GO:0007154	345	0.131
cation transport	GO:0006812	166	0.112
cellular component movement	GO:0006928	20	0.111
ncrna processing	GO:0034470	330	0.107
regulation of nuclear division	GO:0051783	103	0.106
negative regulation of cell cycle process	GO:0010948	86	0.102
macromolecule methylation	GO:0043414	85	0.102
oxoacid metabolic process	GO:0043436	351	0.095
negative regulation of cell division	GO:0051782	66	0.091
reciprocal meiotic recombination	GO:0007131	54	0.090
programmed cell death	GO:0012501	30	0.089
cell death	GO:0008219	30	0.086
microtubule polymerization or depolymerization	GO:0031109	36	0.085
single organism developmental process	GO:0044767	258	0.084	Fly
carboxylic acid metabolic process	GO:0019752	338	0.082
single organism signaling	GO:0044700	208	0.081
cell division	GO:0051301	205	0.079
protein dephosphorylation	GO:0006470	40	0.078
positive regulation of cellular biosynthetic process	GO:0031328	336	0.077
meiotic recombination checkpoint	GO:0051598	9	0.076
positive regulation of rna metabolic process	GO:0051254	294	0.076
microtubule polymerization	GO:0046785	30	0.075
response to chemical	GO:0042221	390	0.074
response to organic substance	GO:0010033	182	0.074
regulation of cellular catabolic process	GO:0031329	195	0.074
intracellular signal transduction	GO:0035556	112	0.070
negative regulation of molecular function	GO:0044092	68	0.068
regulation of cell division	GO:0051302	113	0.066
trna modification	GO:0006400	75	0.065
cell cycle phase transition	GO:0044770	144	0.064
organic acid metabolic process	GO:0006082	352	0.064
proteolysis	GO:0006508	268	0.060
mitochondrion organization	GO:0007005	261	0.060
vesicle mediated transport	GO:0016192	335	0.060
ascospore formation	GO:0030437	107	0.059
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.059
signal transduction	GO:0007165	208	0.058
protein catabolic process	GO:0030163	221	0.057
negative regulation of meiosis	GO:0045835	23	0.056
mitotic cell cycle phase transition	GO:0044772	141	0.053
regulation of response to stimulus	GO:0048583	157	0.052
apoptotic process	GO:0006915	30	0.050
regulation of cell cycle phase transition	GO:1901987	70	0.049
regulation of chromosome segregation	GO:0051983	44	0.048
cell cycle checkpoint	GO:0000075	82	0.048
cell wall organization or biogenesis	GO:0071554	190	0.047
regulation of signaling	GO:0023051	119	0.047
anatomical structure morphogenesis	GO:0009653	160	0.047
rrna metabolic process	GO:0016072	244	0.046
negative regulation of chromatin silencing	GO:0031936	25	0.046
developmental process	GO:0032502	261	0.045	Fly
regulation of gtp catabolic process	GO:0033124	84	0.044
methylation	GO:0032259	101	0.043
replicative cell aging	GO:0001302	46	0.042
regulation of cellular component organization	GO:0051128	334	0.042
anatomical structure development	GO:0048856	160	0.041	Fly
negative regulation of cell cycle	GO:0045786	91	0.040
response to external stimulus	GO:0009605	158	0.040
regulation of intracellular signal transduction	GO:1902531	78	0.039
polyphosphate metabolic process	GO:0006797	12	0.039
positive regulation of catabolic process	GO:0009896	135	0.038
trna processing	GO:0008033	101	0.038
negative regulation of cellular component organization	GO:0051129	109	0.038
endosomal transport	GO:0016197	86	0.037
regulation of protein processing	GO:0070613	34	0.037
protein complex disassembly	GO:0043241	70	0.037
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.035
chromatin modification	GO:0016568	200	0.035
dicarboxylic acid metabolic process	GO:0043648	20	0.034
regulation of catalytic activity	GO:0050790	307	0.034
meiotic cell cycle checkpoint	GO:0033313	10	0.034
protein alkylation	GO:0008213	48	0.034
negative regulation of proteasomal protein catabolic process	GO:1901799	25	0.034
protein localization to mitochondrion	GO:0070585	63	0.033
regulation of cell communication	GO:0010646	124	0.033
covalent chromatin modification	GO:0016569	119	0.033
rna modification	GO:0009451	99	0.032
regulation of mitotic cell cycle	GO:0007346	107	0.032
negative regulation of cellular metabolic process	GO:0031324	407	0.031
trna wobble base modification	GO:0002097	27	0.031
cellular response to pheromone	GO:0071444	88	0.031
cellular response to oxidative stress	GO:0034599	94	0.030
amino acid activation	GO:0043038	35	0.030
negative regulation of protein maturation	GO:1903318	33	0.029
organonitrogen compound biosynthetic process	GO:1901566	314	0.029
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	137	0.028
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.028
regulation of cell cycle	GO:0051726	195	0.028
mitotic sister chromatid separation	GO:0051306	26	0.027
negative regulation of chromosome organization	GO:2001251	39	0.027
ubiquitin dependent protein catabolic process	GO:0006511	181	0.027
dephosphorylation	GO:0016311	127	0.027
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.027
exit from mitosis	GO:0010458	37	0.027
chemical homeostasis	GO:0048878	137	0.027
fungal type cell wall biogenesis	GO:0009272	80	0.027
positive regulation of response to stimulus	GO:0048584	37	0.026
trna metabolic process	GO:0006399	151	0.026
histone modification	GO:0016570	119	0.026
death	GO:0016265	30	0.026
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.026
cell aging	GO:0007569	70	0.025
ion transport	GO:0006811	274	0.025
reproduction of a single celled organism	GO:0032505	191	0.025
response to oxygen containing compound	GO:1901700	61	0.025
metal ion transport	GO:0030001	75	0.025
nitrogen compound transport	GO:0071705	212	0.025
cellular metal ion homeostasis	GO:0006875	78	0.025
single organism catabolic process	GO:0044712	619	0.024
homeostatic process	GO:0042592	227	0.024
trna aminoacylation	GO:0043039	35	0.024
regulation of vesicle mediated transport	GO:0060627	39	0.024
protein targeting to er	GO:0045047	39	0.024
regulation of cellular response to stress	GO:0080135	50	0.023
cell development	GO:0048468	107	0.023
response to extracellular stimulus	GO:0009991	156	0.023
regulation of catabolic process	GO:0009894	199	0.023
external encapsulating structure organization	GO:0045229	146	0.023
regulation of molecular function	GO:0065009	320	0.023
positive regulation of cellular catabolic process	GO:0031331	128	0.023
mitotic cell cycle checkpoint	GO:0007093	56	0.022
regulation of organelle organization	GO:0033043	243	0.022
transmembrane transport	GO:0055085	349	0.022
histone methylation	GO:0016571	28	0.022
cellular protein catabolic process	GO:0044257	213	0.022
histone deacetylation	GO:0016575	26	0.022
detection of stimulus	GO:0051606	4	0.022
guanosine containing compound catabolic process	GO:1901069	109	0.022
dna repair	GO:0006281	236	0.022
macromolecule deacylation	GO:0098732	27	0.021
stress activated protein kinase signaling cascade	GO:0031098	4	0.021
cellular chemical homeostasis	GO:0055082	123	0.021
protein maturation	GO:0051604	76	0.021
regulation of biological quality	GO:0065008	391	0.021
reproductive process in single celled organism	GO:0022413	145	0.021
positive regulation of apoptotic process	GO:0043065	3	0.021
growth	GO:0040007	157	0.021
peptidyl amino acid modification	GO:0018193	116	0.020
reciprocal dna recombination	GO:0035825	54	0.020
regulation of response to external stimulus	GO:0032101	20	0.020
modification dependent protein catabolic process	GO:0019941	181	0.020
negative regulation of protein metabolic process	GO:0051248	85	0.020
golgi vesicle transport	GO:0048193	188	0.020
positive regulation of catalytic activity	GO:0043085	178	0.020
response to starvation	GO:0042594	96	0.020
regulation of nucleotide catabolic process	GO:0030811	106	0.020
cellular protein complex assembly	GO:0043623	209	0.020	Human
response to oxidative stress	GO:0006979	99	0.020
negative regulation of protein catabolic process	GO:0042177	27	0.019
regulation of protein maturation	GO:1903317	34	0.019
cellular cation homeostasis	GO:0030003	100	0.019
purine containing compound metabolic process	GO:0072521	400	0.019
regulation of mapk cascade	GO:0043408	22	0.019
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.019
er to golgi vesicle mediated transport	GO:0006888	86	0.018
response to organic cyclic compound	GO:0014070	1	0.018
cellular protein complex disassembly	GO:0043624	42	0.018
regulation of transcription by pheromones	GO:0009373	14	0.018
cellular amino acid metabolic process	GO:0006520	225	0.018
regulation of chromosome organization	GO:0033044	66	0.018
cell wall organization	GO:0071555	146	0.017
cation homeostasis	GO:0055080	105	0.017
mitochondrial translation	GO:0032543	52	0.017
response to monosaccharide	GO:0034284	13	0.017
cell cycle g1 s phase transition	GO:0044843	64	0.017
regulation of histone methylation	GO:0031060	8	0.017
negative regulation of chromatin modification	GO:1903309	9	0.017
positive regulation of transcription from rna polymerase i promoter	GO:0045943	19	0.017
cell differentiation	GO:0030154	161	0.016	Fly
sporulation	GO:0043934	132	0.016
regulation of dna dependent dna replication	GO:0090329	37	0.016
cellular response to oxygen containing compound	GO:1901701	43	0.016
cellular homeostasis	GO:0019725	138	0.016
regulation of response to stress	GO:0080134	57	0.016
fungal type cell wall organization	GO:0031505	145	0.016
protein processing	GO:0016485	64	0.016
negative regulation of proteolysis	GO:0045861	33	0.016
positive regulation of sequence specific dna binding transcription factor activity	GO:0051091	2	0.016
response to biotic stimulus	GO:0009607	8	0.016
protein transport	GO:0015031	345	0.015
single organism membrane fusion	GO:0044801	71	0.015
organic acid biosynthetic process	GO:0016053	152	0.015
positive regulation of secretion by cell	GO:1903532	2	0.015
mitochondrial transport	GO:0006839	76	0.015
alpha amino acid metabolic process	GO:1901605	124	0.015
mapk cascade	GO:0000165	30	0.015
regulation of transport	GO:0051049	85	0.015
peroxisome organization	GO:0007031	68	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.015
ribonucleoprotein complex subunit organization	GO:0071826	152	0.015
aging	GO:0007568	71	0.015
organelle fusion	GO:0048284	85	0.015
alpha amino acid biosynthetic process	GO:1901607	91	0.015
regulation of dna metabolic process	GO:0051052	100	0.015
cellular response to extracellular stimulus	GO:0031668	150	0.014
establishment of protein localization to membrane	GO:0090150	99	0.014
ribosome biogenesis	GO:0042254	335	0.014
positive regulation of cell communication	GO:0010647	28	0.014
regulation of protein metabolic process	GO:0051246	237	0.014
spore wall biogenesis	GO:0070590	52	0.014
establishment of protein localization to mitochondrion	GO:0072655	63	0.014
glutamine family amino acid metabolic process	GO:0009064	31	0.014
negative regulation of cell communication	GO:0010648	33	0.014
protein acylation	GO:0043543	66	0.014
single organism cellular localization	GO:1902580	375	0.014
protein methylation	GO:0006479	48	0.014
ribonucleoprotein complex assembly	GO:0022618	143	0.014
chromosome segregation	GO:0007059	159	0.013
dna integrity checkpoint	GO:0031570	41	0.013
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	40	0.013
dna replication initiation	GO:0006270	48	0.013
positive regulation of purine nucleotide catabolic process	GO:0033123	97	0.013
negative regulation of rna metabolic process	GO:0051253	262	0.013
cellular protein complex localization	GO:0034629	28	0.013
gene silencing by rna	GO:0031047	3	0.013
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.013
gtp metabolic process	GO:0046039	107	0.013
posttranscriptional regulation of gene expression	GO:0010608	115	0.013
g1 s transition of mitotic cell cycle	GO:0000082	64	0.013
endocytosis	GO:0006897	90	0.013
chromatin organization	GO:0006325	242	0.013
negative regulation of protein modification process	GO:0031400	37	0.013
negative regulation of rna biosynthetic process	GO:1902679	260	0.013
purine ribonucleotide catabolic process	GO:0009154	327	0.013
negative regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032435	24	0.013
cellular response to chemical stimulus	GO:0070887	315	0.013
positive regulation of organelle organization	GO:0010638	85	0.013
regulation of phosphate metabolic process	GO:0019220	230	0.013
negative regulation of dna metabolic process	GO:0051053	36	0.012
regulation of purine nucleotide metabolic process	GO:1900542	109	0.012
cellular response to external stimulus	GO:0071496	150	0.012
cellular lipid metabolic process	GO:0044255	229	0.012
mitotic sister chromatid segregation	GO:0000070	85	0.012
sexual sporulation	GO:0034293	113	0.012
vitamin metabolic process	GO:0006766	41	0.012
stress activated mapk cascade	GO:0051403	4	0.012
negative regulation of catabolic process	GO:0009895	43	0.012
purine ribonucleoside metabolic process	GO:0046128	380	0.012
regulation of mitosis	GO:0007088	65	0.012
nucleoside metabolic process	GO:0009116	394	0.012
cellular developmental process	GO:0048869	191	0.012	Fly
regulation of transferase activity	GO:0051338	83	0.012
positive regulation of programmed cell death	GO:0043068	3	0.012
positive regulation of intracellular transport	GO:0032388	4	0.012
organonitrogen compound catabolic process	GO:1901565	404	0.012
er associated ubiquitin dependent protein catabolic process	GO:0030433	46	0.012
regulation of hydrolase activity	GO:0051336	133	0.011
meiotic chromosome segregation	GO:0045132	31	0.011
small molecule biosynthetic process	GO:0044283	258	0.011
sister chromatid segregation	GO:0000819	93	0.011
mrna export from nucleus	GO:0006406	60	0.011
positive regulation of cytoplasmic transport	GO:1903651	4	0.011
regulation of proteolysis	GO:0030162	44	0.011
rrna processing	GO:0006364	227	0.011
regulation of cellular localization	GO:0060341	50	0.011
regulation of mitotic sister chromatid segregation	GO:0033047	30	0.011
positive regulation of cellular component organization	GO:0051130	116	0.011
regulation of protein catabolic process	GO:0042176	40	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.010
regulation of gtpase activity	GO:0043087	84	0.010
mitotic spindle checkpoint	GO:0071174	34	0.010
negative regulation of mitotic cell cycle	GO:0045930	63	0.010
response to temperature stimulus	GO:0009266	74	0.010
trna pseudouridine synthesis	GO:0031119	7	0.010
maturation of lsu rrna	GO:0000470	39	0.010
protein complex localization	GO:0031503	32	0.010
cell wall assembly	GO:0070726	54	0.010
exocytosis	GO:0006887	42	0.010
cellular response to organic substance	GO:0071310	159	0.010

CCT2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.042
	nervous system disease	DOID:863	0	0.015

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