| spindle assembly | GO:0051225 | 9 | 0.963 | Fly |
| protein folding | GO:0006457 | 94 | 0.942 | |
| organelle fission | GO:0048285 | 272 | 0.918 | Fly |
| mitotic nuclear division | GO:0007067 | 131 | 0.889 | Fly |
| mitotic cell cycle | GO:0000278 | 306 | 0.812 | Fly |
| nuclear division | GO:0000280 | 263 | 0.783 | Fly |
| spindle organization | GO:0007051 | 37 | 0.780 | Fly |
| sexual reproduction | GO:0019953 | 216 | 0.702 | Mouse |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 13 | 0.688 | Fly |
| meiotic cell cycle process | GO:1903046 | 229 | 0.662 | |
| single organism reproductive process | GO:0044702 | 159 | 0.644 | Mouse |
| multi organism reproductive process | GO:0044703 | 216 | 0.629 | Mouse |
| mitotic cell cycle process | GO:1903047 | 294 | 0.602 | Fly |
| mitotic spindle organization | GO:0007052 | 30 | 0.575 | Fly |
| microtubule based process | GO:0007017 | 117 | 0.506 | Fly |
| microtubule cytoskeleton organization | GO:0000226 | 109 | 0.493 | Fly |
| meiotic nuclear division | GO:0007126 | 163 | 0.448 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 286 | 0.445 | |
| regulation of meiosis | GO:0040020 | 42 | 0.443 | |
| meiosis i | GO:0007127 | 92 | 0.435 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 286 | 0.422 | |
| protein complex assembly | GO:0006461 | 302 | 0.411 | Human Fly |
| protein complex biogenesis | GO:0070271 | 314 | 0.405 | Human Fly |
| regulation of meiotic cell cycle | GO:0051445 | 43 | 0.326 | |
| organelle assembly | GO:0070925 | 118 | 0.318 | Fly |
| positive regulation of macromolecule metabolic process | GO:0010604 | 394 | 0.308 | |
| multi organism process | GO:0051704 | 233 | 0.305 | Mouse |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 409 | 0.302 | |
| spindle assembly involved in mitosis | GO:0090307 | 4 | 0.283 | Fly |
| positive regulation of gene expression | GO:0010628 | 321 | 0.267 | |
| regulation of cell cycle process | GO:0010564 | 150 | 0.254 | |
| negative regulation of nuclear division | GO:0051784 | 62 | 0.245 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 394 | 0.234 | |
| reproductive process | GO:0022414 | 248 | 0.213 | Mouse |
| positive regulation of transcription dna templated | GO:0045893 | 286 | 0.211 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 325 | 0.201 | |
| cytoskeleton organization | GO:0007010 | 230 | 0.195 | Fly |
| cellular amino acid biosynthetic process | GO:0008652 | 118 | 0.183 | |
| positive regulation of biosynthetic process | GO:0009891 | 336 | 0.180 | |
| signaling | GO:0023052 | 208 | 0.169 | |
| meiotic cell cycle | GO:0051321 | 272 | 0.164 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 252 | 0.163 | |
| fungal type cell wall organization or biogenesis | GO:0071852 | 169 | 0.154 | |
| negative regulation of meiotic cell cycle | GO:0051447 | 24 | 0.135 | |
| cell communication | GO:0007154 | 345 | 0.131 | |
| cation transport | GO:0006812 | 166 | 0.112 | |
| cellular component movement | GO:0006928 | 20 | 0.111 | |
| ncrna processing | GO:0034470 | 330 | 0.107 | |
| regulation of nuclear division | GO:0051783 | 103 | 0.106 | |
| negative regulation of cell cycle process | GO:0010948 | 86 | 0.102 | |
| macromolecule methylation | GO:0043414 | 85 | 0.102 | |
| oxoacid metabolic process | GO:0043436 | 351 | 0.095 | |
| negative regulation of cell division | GO:0051782 | 66 | 0.091 | |
| reciprocal meiotic recombination | GO:0007131 | 54 | 0.090 | |
| programmed cell death | GO:0012501 | 30 | 0.089 | |
| cell death | GO:0008219 | 30 | 0.086 | |
| microtubule polymerization or depolymerization | GO:0031109 | 36 | 0.085 | |
| single organism developmental process | GO:0044767 | 258 | 0.084 | Fly |
| carboxylic acid metabolic process | GO:0019752 | 338 | 0.082 | |
| single organism signaling | GO:0044700 | 208 | 0.081 | |
| cell division | GO:0051301 | 205 | 0.079 | |
| protein dephosphorylation | GO:0006470 | 40 | 0.078 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 336 | 0.077 | |
| meiotic recombination checkpoint | GO:0051598 | 9 | 0.076 | |
| positive regulation of rna metabolic process | GO:0051254 | 294 | 0.076 | |
| microtubule polymerization | GO:0046785 | 30 | 0.075 | |
| response to chemical | GO:0042221 | 390 | 0.074 | |
| response to organic substance | GO:0010033 | 182 | 0.074 | |
| regulation of cellular catabolic process | GO:0031329 | 195 | 0.074 | |
| intracellular signal transduction | GO:0035556 | 112 | 0.070 | |
| negative regulation of molecular function | GO:0044092 | 68 | 0.068 | |
| regulation of cell division | GO:0051302 | 113 | 0.066 | |
| trna modification | GO:0006400 | 75 | 0.065 | |
| cell cycle phase transition | GO:0044770 | 144 | 0.064 | |
| organic acid metabolic process | GO:0006082 | 352 | 0.064 | |
| proteolysis | GO:0006508 | 268 | 0.060 | |
| mitochondrion organization | GO:0007005 | 261 | 0.060 | |
| vesicle mediated transport | GO:0016192 | 335 | 0.060 | |
| ascospore formation | GO:0030437 | 107 | 0.059 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 412 | 0.059 | |
| signal transduction | GO:0007165 | 208 | 0.058 | |
| protein catabolic process | GO:0030163 | 221 | 0.057 | |
| negative regulation of meiosis | GO:0045835 | 23 | 0.056 | |
| mitotic cell cycle phase transition | GO:0044772 | 141 | 0.053 | |
| regulation of response to stimulus | GO:0048583 | 157 | 0.052 | |
| apoptotic process | GO:0006915 | 30 | 0.050 | |
| regulation of cell cycle phase transition | GO:1901987 | 70 | 0.049 | |
| regulation of chromosome segregation | GO:0051983 | 44 | 0.048 | |
| cell cycle checkpoint | GO:0000075 | 82 | 0.048 | |
| cell wall organization or biogenesis | GO:0071554 | 190 | 0.047 | |
| regulation of signaling | GO:0023051 | 119 | 0.047 | |
| anatomical structure morphogenesis | GO:0009653 | 160 | 0.047 | |
| rrna metabolic process | GO:0016072 | 244 | 0.046 | |
| negative regulation of chromatin silencing | GO:0031936 | 25 | 0.046 | |
| developmental process | GO:0032502 | 261 | 0.045 | Fly |
| regulation of gtp catabolic process | GO:0033124 | 84 | 0.044 | |
| methylation | GO:0032259 | 101 | 0.043 | |
| replicative cell aging | GO:0001302 | 46 | 0.042 | |
| regulation of cellular component organization | GO:0051128 | 334 | 0.042 | |
| anatomical structure development | GO:0048856 | 160 | 0.041 | Fly |
| negative regulation of cell cycle | GO:0045786 | 91 | 0.040 | |
| response to external stimulus | GO:0009605 | 158 | 0.040 | |
| regulation of intracellular signal transduction | GO:1902531 | 78 | 0.039 | |
| polyphosphate metabolic process | GO:0006797 | 12 | 0.039 | |
| positive regulation of catabolic process | GO:0009896 | 135 | 0.038 | |
| trna processing | GO:0008033 | 101 | 0.038 | |
| negative regulation of cellular component organization | GO:0051129 | 109 | 0.038 | |
| endosomal transport | GO:0016197 | 86 | 0.037 | |
| regulation of protein processing | GO:0070613 | 34 | 0.037 | |
| protein complex disassembly | GO:0043241 | 70 | 0.037 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 68 | 0.035 | |
| chromatin modification | GO:0016568 | 200 | 0.035 | |
| dicarboxylic acid metabolic process | GO:0043648 | 20 | 0.034 | |
| regulation of catalytic activity | GO:0050790 | 307 | 0.034 | |
| meiotic cell cycle checkpoint | GO:0033313 | 10 | 0.034 | |
| protein alkylation | GO:0008213 | 48 | 0.034 | |
| negative regulation of proteasomal protein catabolic process | GO:1901799 | 25 | 0.034 | |
| protein localization to mitochondrion | GO:0070585 | 63 | 0.033 | |
| regulation of cell communication | GO:0010646 | 124 | 0.033 | |
| covalent chromatin modification | GO:0016569 | 119 | 0.033 | |
| rna modification | GO:0009451 | 99 | 0.032 | |
| regulation of mitotic cell cycle | GO:0007346 | 107 | 0.032 | |
| negative regulation of cellular metabolic process | GO:0031324 | 407 | 0.031 | |
| trna wobble base modification | GO:0002097 | 27 | 0.031 | |
| cellular response to pheromone | GO:0071444 | 88 | 0.031 | |
| cellular response to oxidative stress | GO:0034599 | 94 | 0.030 | |
| amino acid activation | GO:0043038 | 35 | 0.030 | |
| negative regulation of protein maturation | GO:1903318 | 33 | 0.029 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 314 | 0.029 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 137 | 0.028 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 198 | 0.028 | |
| regulation of cell cycle | GO:0051726 | 195 | 0.028 | |
| mitotic sister chromatid separation | GO:0051306 | 26 | 0.027 | |
| negative regulation of chromosome organization | GO:2001251 | 39 | 0.027 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 181 | 0.027 | |
| dephosphorylation | GO:0016311 | 127 | 0.027 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 260 | 0.027 | |
| exit from mitosis | GO:0010458 | 37 | 0.027 | |
| chemical homeostasis | GO:0048878 | 137 | 0.027 | |
| fungal type cell wall biogenesis | GO:0009272 | 80 | 0.027 | |
| positive regulation of response to stimulus | GO:0048584 | 37 | 0.026 | |
| trna metabolic process | GO:0006399 | 151 | 0.026 | |
| histone modification | GO:0016570 | 119 | 0.026 | |
| death | GO:0016265 | 30 | 0.026 | |
| sexual sporulation resulting in formation of a cellular spore | GO:0043935 | 113 | 0.026 | |
| cell aging | GO:0007569 | 70 | 0.025 | |
| ion transport | GO:0006811 | 274 | 0.025 | |
| reproduction of a single celled organism | GO:0032505 | 191 | 0.025 | |
| response to oxygen containing compound | GO:1901700 | 61 | 0.025 | |
| metal ion transport | GO:0030001 | 75 | 0.025 | |
| nitrogen compound transport | GO:0071705 | 212 | 0.025 | |
| cellular metal ion homeostasis | GO:0006875 | 78 | 0.025 | |
| single organism catabolic process | GO:0044712 | 619 | 0.024 | |
| homeostatic process | GO:0042592 | 227 | 0.024 | |
| trna aminoacylation | GO:0043039 | 35 | 0.024 | |
| regulation of vesicle mediated transport | GO:0060627 | 39 | 0.024 | |
| protein targeting to er | GO:0045047 | 39 | 0.024 | |
| regulation of cellular response to stress | GO:0080135 | 50 | 0.023 | |
| cell development | GO:0048468 | 107 | 0.023 | |
| response to extracellular stimulus | GO:0009991 | 156 | 0.023 | |
| regulation of catabolic process | GO:0009894 | 199 | 0.023 | |
| external encapsulating structure organization | GO:0045229 | 146 | 0.023 | |
| regulation of molecular function | GO:0065009 | 320 | 0.023 | |
| positive regulation of cellular catabolic process | GO:0031331 | 128 | 0.023 | |
| mitotic cell cycle checkpoint | GO:0007093 | 56 | 0.022 | |
| regulation of organelle organization | GO:0033043 | 243 | 0.022 | |
| transmembrane transport | GO:0055085 | 349 | 0.022 | |
| histone methylation | GO:0016571 | 28 | 0.022 | |
| cellular protein catabolic process | GO:0044257 | 213 | 0.022 | |
| histone deacetylation | GO:0016575 | 26 | 0.022 | |
| detection of stimulus | GO:0051606 | 4 | 0.022 | |
| guanosine containing compound catabolic process | GO:1901069 | 109 | 0.022 | |
| dna repair | GO:0006281 | 236 | 0.022 | |
| macromolecule deacylation | GO:0098732 | 27 | 0.021 | |
| stress activated protein kinase signaling cascade | GO:0031098 | 4 | 0.021 | |
| cellular chemical homeostasis | GO:0055082 | 123 | 0.021 | |
| protein maturation | GO:0051604 | 76 | 0.021 | |
| regulation of biological quality | GO:0065008 | 391 | 0.021 | |
| reproductive process in single celled organism | GO:0022413 | 145 | 0.021 | |
| positive regulation of apoptotic process | GO:0043065 | 3 | 0.021 | |
| growth | GO:0040007 | 157 | 0.021 | |
| peptidyl amino acid modification | GO:0018193 | 116 | 0.020 | |
| reciprocal dna recombination | GO:0035825 | 54 | 0.020 | |
| regulation of response to external stimulus | GO:0032101 | 20 | 0.020 | |
| modification dependent protein catabolic process | GO:0019941 | 181 | 0.020 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.020 | |
| golgi vesicle transport | GO:0048193 | 188 | 0.020 | |
| positive regulation of catalytic activity | GO:0043085 | 178 | 0.020 | |
| response to starvation | GO:0042594 | 96 | 0.020 | |
| regulation of nucleotide catabolic process | GO:0030811 | 106 | 0.020 | |
| cellular protein complex assembly | GO:0043623 | 209 | 0.020 | Human |
| response to oxidative stress | GO:0006979 | 99 | 0.020 | |
| negative regulation of protein catabolic process | GO:0042177 | 27 | 0.019 | |
| regulation of protein maturation | GO:1903317 | 34 | 0.019 | |
| cellular cation homeostasis | GO:0030003 | 100 | 0.019 | |
| purine containing compound metabolic process | GO:0072521 | 400 | 0.019 | |
| regulation of mapk cascade | GO:0043408 | 22 | 0.019 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 295 | 0.019 | |
| er to golgi vesicle mediated transport | GO:0006888 | 86 | 0.018 | |
| response to organic cyclic compound | GO:0014070 | 1 | 0.018 | |
| cellular protein complex disassembly | GO:0043624 | 42 | 0.018 | |
| regulation of transcription by pheromones | GO:0009373 | 14 | 0.018 | |
| cellular amino acid metabolic process | GO:0006520 | 225 | 0.018 | |
| regulation of chromosome organization | GO:0033044 | 66 | 0.018 | |
| cell wall organization | GO:0071555 | 146 | 0.017 | |
| cation homeostasis | GO:0055080 | 105 | 0.017 | |
| mitochondrial translation | GO:0032543 | 52 | 0.017 | |
| response to monosaccharide | GO:0034284 | 13 | 0.017 | |
| cell cycle g1 s phase transition | GO:0044843 | 64 | 0.017 | |
| regulation of histone methylation | GO:0031060 | 8 | 0.017 | |
| negative regulation of chromatin modification | GO:1903309 | 9 | 0.017 | |
| positive regulation of transcription from rna polymerase i promoter | GO:0045943 | 19 | 0.017 | |
| cell differentiation | GO:0030154 | 161 | 0.016 | Fly |
| sporulation | GO:0043934 | 132 | 0.016 | |
| regulation of dna dependent dna replication | GO:0090329 | 37 | 0.016 | |
| cellular response to oxygen containing compound | GO:1901701 | 43 | 0.016 | |
| cellular homeostasis | GO:0019725 | 138 | 0.016 | |
| regulation of response to stress | GO:0080134 | 57 | 0.016 | |
| fungal type cell wall organization | GO:0031505 | 145 | 0.016 | |
| protein processing | GO:0016485 | 64 | 0.016 | |
| negative regulation of proteolysis | GO:0045861 | 33 | 0.016 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 2 | 0.016 | |
| response to biotic stimulus | GO:0009607 | 8 | 0.016 | |
| protein transport | GO:0015031 | 345 | 0.015 | |
| single organism membrane fusion | GO:0044801 | 71 | 0.015 | |
| organic acid biosynthetic process | GO:0016053 | 152 | 0.015 | |
| positive regulation of secretion by cell | GO:1903532 | 2 | 0.015 | |
| mitochondrial transport | GO:0006839 | 76 | 0.015 | |
| alpha amino acid metabolic process | GO:1901605 | 124 | 0.015 | |
| mapk cascade | GO:0000165 | 30 | 0.015 | |
| regulation of transport | GO:0051049 | 85 | 0.015 | |
| peroxisome organization | GO:0007031 | 68 | 0.015 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 291 | 0.015 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 152 | 0.015 | |
| aging | GO:0007568 | 71 | 0.015 | |
| organelle fusion | GO:0048284 | 85 | 0.015 | |
| alpha amino acid biosynthetic process | GO:1901607 | 91 | 0.015 | |
| regulation of dna metabolic process | GO:0051052 | 100 | 0.015 | |
| cellular response to extracellular stimulus | GO:0031668 | 150 | 0.014 | |
| establishment of protein localization to membrane | GO:0090150 | 99 | 0.014 | |
| ribosome biogenesis | GO:0042254 | 335 | 0.014 | |
| positive regulation of cell communication | GO:0010647 | 28 | 0.014 | |
| regulation of protein metabolic process | GO:0051246 | 237 | 0.014 | |
| spore wall biogenesis | GO:0070590 | 52 | 0.014 | |
| establishment of protein localization to mitochondrion | GO:0072655 | 63 | 0.014 | |
| glutamine family amino acid metabolic process | GO:0009064 | 31 | 0.014 | |
| negative regulation of cell communication | GO:0010648 | 33 | 0.014 | |
| protein acylation | GO:0043543 | 66 | 0.014 | |
| single organism cellular localization | GO:1902580 | 375 | 0.014 | |
| protein methylation | GO:0006479 | 48 | 0.014 | |
| ribonucleoprotein complex assembly | GO:0022618 | 143 | 0.014 | |
| chromosome segregation | GO:0007059 | 159 | 0.013 | |
| dna integrity checkpoint | GO:0031570 | 41 | 0.013 | |
| regulation of transcription elongation from rna polymerase ii promoter | GO:0034243 | 40 | 0.013 | |
| dna replication initiation | GO:0006270 | 48 | 0.013 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 97 | 0.013 | |
| negative regulation of rna metabolic process | GO:0051253 | 262 | 0.013 | |
| cellular protein complex localization | GO:0034629 | 28 | 0.013 | |
| gene silencing by rna | GO:0031047 | 3 | 0.013 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 57 | 0.013 | |
| gtp metabolic process | GO:0046039 | 107 | 0.013 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 115 | 0.013 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 64 | 0.013 | |
| endocytosis | GO:0006897 | 90 | 0.013 | |
| chromatin organization | GO:0006325 | 242 | 0.013 | |
| negative regulation of protein modification process | GO:0031400 | 37 | 0.013 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 260 | 0.013 | |
| purine ribonucleotide catabolic process | GO:0009154 | 327 | 0.013 | |
| negative regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032435 | 24 | 0.013 | |
| cellular response to chemical stimulus | GO:0070887 | 315 | 0.013 | |
| positive regulation of organelle organization | GO:0010638 | 85 | 0.013 | |
| regulation of phosphate metabolic process | GO:0019220 | 230 | 0.013 | |
| negative regulation of dna metabolic process | GO:0051053 | 36 | 0.012 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 109 | 0.012 | |
| cellular response to external stimulus | GO:0071496 | 150 | 0.012 | |
| cellular lipid metabolic process | GO:0044255 | 229 | 0.012 | |
| mitotic sister chromatid segregation | GO:0000070 | 85 | 0.012 | |
| sexual sporulation | GO:0034293 | 113 | 0.012 | |
| vitamin metabolic process | GO:0006766 | 41 | 0.012 | |
| stress activated mapk cascade | GO:0051403 | 4 | 0.012 | |
| negative regulation of catabolic process | GO:0009895 | 43 | 0.012 | |
| purine ribonucleoside metabolic process | GO:0046128 | 380 | 0.012 | |
| regulation of mitosis | GO:0007088 | 65 | 0.012 | |
| nucleoside metabolic process | GO:0009116 | 394 | 0.012 | |
| cellular developmental process | GO:0048869 | 191 | 0.012 | Fly |
| regulation of transferase activity | GO:0051338 | 83 | 0.012 | |
| positive regulation of programmed cell death | GO:0043068 | 3 | 0.012 | |
| positive regulation of intracellular transport | GO:0032388 | 4 | 0.012 | |
| organonitrogen compound catabolic process | GO:1901565 | 404 | 0.012 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 46 | 0.012 | |
| regulation of hydrolase activity | GO:0051336 | 133 | 0.011 | |
| meiotic chromosome segregation | GO:0045132 | 31 | 0.011 | |
| small molecule biosynthetic process | GO:0044283 | 258 | 0.011 | |
| sister chromatid segregation | GO:0000819 | 93 | 0.011 | |
| mrna export from nucleus | GO:0006406 | 60 | 0.011 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 4 | 0.011 | |
| regulation of proteolysis | GO:0030162 | 44 | 0.011 | |
| rrna processing | GO:0006364 | 227 | 0.011 | |
| regulation of cellular localization | GO:0060341 | 50 | 0.011 | |
| regulation of mitotic sister chromatid segregation | GO:0033047 | 30 | 0.011 | |
| positive regulation of cellular component organization | GO:0051130 | 116 | 0.011 | |
| regulation of protein catabolic process | GO:0042176 | 40 | 0.011 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 327 | 0.010 | |
| regulation of gtpase activity | GO:0043087 | 84 | 0.010 | |
| mitotic spindle checkpoint | GO:0071174 | 34 | 0.010 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 63 | 0.010 | |
| response to temperature stimulus | GO:0009266 | 74 | 0.010 | |
| trna pseudouridine synthesis | GO:0031119 | 7 | 0.010 | |
| maturation of lsu rrna | GO:0000470 | 39 | 0.010 | |
| protein complex localization | GO:0031503 | 32 | 0.010 | |
| cell wall assembly | GO:0070726 | 54 | 0.010 | |
| exocytosis | GO:0006887 | 42 | 0.010 | |
| cellular response to organic substance | GO:0071310 | 159 | 0.010 | |