Saccharomyces cerevisiae

150 known processes

KAR2 (YJL034W)

Kar2p

(Aliases: GRP78)

KAR2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
modification dependent macromolecule catabolic processGO:00436322030.999
ubiquitin dependent protein catabolic processGO:00065111810.998
srp dependent cotranslational protein targeting to membraneGO:0006614140.998
transmembrane transportGO:00550853490.995
protein transmembrane transportGO:0071806820.993
protein localization to endoplasmic reticulumGO:0070972470.992
intracellular protein transmembrane transportGO:0065002800.988
protein targeting to erGO:0045047390.988
proteasomal protein catabolic processGO:00104981410.987
cellular protein catabolic processGO:00442572130.982
protein catabolic processGO:00301632210.981
establishment of protein localization to endoplasmic reticulumGO:0072599400.980
modification dependent protein catabolic processGO:00199411810.979
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611370.974
er associated ubiquitin dependent protein catabolic processGO:0030433460.970
protein foldingGO:0006457940.960
proteolysis involved in cellular protein catabolic processGO:00516031980.943
proteolysisGO:00065082680.941
cellular macromolecule catabolic processGO:00442653630.932
srp dependent cotranslational protein targeting to membrane translocationGO:000661690.928
cotranslational protein targeting to membraneGO:0006613150.911
single organism cellular localizationGO:19025803750.892
establishment of protein localization to organelleGO:00725942780.844
protein targetingGO:00066052720.823
establishment of protein localizationGO:00451843670.817
single organism membrane organizationGO:00448022750.777
intracellular protein transportGO:00068863190.748
protein targeting to membraneGO:0006612520.726
protein transportGO:00150313450.620
protein modification by small protein conjugationGO:00324461440.563
Mouse
protein localization to organelleGO:00333653370.544
protein refoldingGO:0042026160.529
establishment of protein localization to membraneGO:0090150990.523
membrane organizationGO:00610242760.499
posttranslational protein targeting to membraneGO:0006620170.488
macromolecule catabolic processGO:00090573830.479
protein localization to membraneGO:00726571020.321
protein modification by small protein conjugation or removalGO:00706471720.308
Mouse
intracellular protein transmembrane importGO:0044743670.290
purine containing compound catabolic processGO:00725233320.268
carbohydrate derivative catabolic processGO:19011363390.261
nucleus organizationGO:0006997620.255
protein targeting to mitochondrionGO:0006626560.243
ribonucleoside metabolic processGO:00091193890.243
regulation of protein modification processGO:00313991100.226
Mouse
nucleoside phosphate metabolic processGO:00067534580.223
response to external stimulusGO:00096051580.223
Human Zebrafish
nucleoside catabolic processGO:00091643350.206
ribonucleoside catabolic processGO:00424543320.201
single organism catabolic processGO:00447126190.200
purine ribonucleotide catabolic processGO:00091543270.197
ribonucleoprotein complex subunit organizationGO:00718261520.192
apoptotic processGO:0006915300.191
Human
ncrna processingGO:00344703300.168
response to nutrient levelsGO:00316671500.156
Human
ribonucleotide metabolic processGO:00092593770.152
cellular response to starvationGO:0009267900.147
Human
purine nucleoside triphosphate metabolic processGO:00091443560.146
regulation of protein ubiquitinationGO:0031396200.141
Mouse
cytoskeleton organizationGO:00070102300.139
Fly
regulation of molecular functionGO:00650093200.133
Yeast Mouse
response to extracellular stimulusGO:00099911560.127
Human
protein localization to mitochondrionGO:0070585630.126
mitochondrial transportGO:0006839760.120
reproductive processGO:00224142480.120
ribose phosphate metabolic processGO:00196933840.116
purine nucleoside catabolic processGO:00061523300.115
glycosyl compound catabolic processGO:19016583350.113
glycosyl compound metabolic processGO:19016573980.112
protein ubiquitinationGO:00165671180.109
Mouse
rrna metabolic processGO:00160722440.108
regulation of biological qualityGO:00650083910.104
Human
establishment of protein localization to mitochondrionGO:0072655630.102
programmed cell deathGO:0012501300.099
Human
nucleoside metabolic processGO:00091163940.098
purine containing compound metabolic processGO:00725214000.098
purine ribonucleoside metabolic processGO:00461283800.097
regulation of localizationGO:00328791270.092
Human
mitochondrion organizationGO:00070052610.088
response to organic substanceGO:00100331820.088
rrna processingGO:00063642270.087
purine ribonucleoside triphosphate metabolic processGO:00092053540.085
nucleoside triphosphate catabolic processGO:00091433290.084
nucleoside triphosphate metabolic processGO:00091413640.083
protein importGO:00170381220.082
rna splicing via transesterification reactionsGO:00003751180.079
protein folding in endoplasmic reticulumGO:0034975130.079
carbohydrate derivative metabolic processGO:19011355490.077
sexual reproductionGO:00199532160.075
organophosphate metabolic processGO:00196375970.075
positive regulation of macromolecule metabolic processGO:00106043940.074
Mouse
multi organism processGO:00517042330.074
nucleotide catabolic processGO:00091663300.073
regulation of protein metabolic processGO:00512462370.072
Mouse
organophosphate catabolic processGO:00464343380.072
developmental processGO:00325022610.071
Human Mouse Worm
regulation of protein modification by small protein conjugation or removalGO:1903320290.071
Mouse
rna splicingGO:00083801310.070
cell communicationGO:00071543450.070
Human Mouse Worm
nucleobase containing compound catabolic processGO:00346554790.069
response to topologically incorrect proteinGO:0035966380.069
positive regulation of protein modification by small protein conjugation or removalGO:1903322120.069
Mouse
organic cyclic compound catabolic processGO:19013614990.069
nucleobase containing small molecule metabolic processGO:00550864910.069
microtubule organizing center organizationGO:0031023330.068
Fly
organonitrogen compound catabolic processGO:19015654040.068
purine nucleotide catabolic processGO:00061953280.067
nucleoside phosphate catabolic processGO:19012923310.066
purine ribonucleotide metabolic processGO:00091503720.066
response to chemicalGO:00422213900.066
secretionGO:0046903500.065
macromolecular complex disassemblyGO:0032984800.065
cellular nitrogen compound catabolic processGO:00442704940.062
cellular response to topologically incorrect proteinGO:0035967320.059
Mouse Worm
purine nucleoside metabolic processGO:00422783800.059
posttranscriptional regulation of gene expressionGO:00106081150.059
Fly
microtubule cytoskeleton organizationGO:00002261090.058
Fly
multi organism reproductive processGO:00447032160.058
purine nucleotide metabolic processGO:00061633760.058
positive regulation of nitrogen compound metabolic processGO:00511734120.057
Mouse
response to starvationGO:0042594960.057
Human
regulation of catalytic activityGO:00507903070.056
Yeast Mouse
signalingGO:00230522080.055
Mouse Worm
multi organism cellular processGO:00447641200.054
purine ribonucleoside catabolic processGO:00461303300.053
regulation of cellular component organizationGO:00511283340.051
cell deathGO:0008219300.049
Human
heterocycle catabolic processGO:00467004940.049
purine nucleoside triphosphate catabolic processGO:00091463290.049
ribonucleotide catabolic processGO:00092613270.046
cation transportGO:00068121660.045
ion transportGO:00068112740.045
homeostatic processGO:00425922270.045
organelle fissionGO:00482852720.044
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:00003771090.044
signal transductionGO:00071652080.043
Mouse Worm
regulation of cellular component biogenesisGO:00440871120.041
negative regulation of macromolecule metabolic processGO:00106053750.041
Fly
misfolded or incompletely synthesized protein catabolic processGO:0006515210.041
regulation of cellular protein metabolic processGO:00322682320.040
Mouse
chaperone mediated protein foldingGO:006107730.040
gene silencing by rnaGO:003104730.038
Fly
protein phosphorylationGO:00064681970.038
Mouse
deathGO:0016265300.038
Human
positive regulation of molecular functionGO:00440931850.037
Mouse
mrna splicing via spliceosomeGO:00003981080.037
phosphorylationGO:00163102910.037
Mouse
gene silencingGO:00164581510.036
Fly
positive regulation of protein metabolic processGO:0051247930.036
Mouse
single organism signalingGO:00447002080.036
Mouse Worm
regulation of response to stimulusGO:00485831570.035
Mouse
regulation of gene expression epigeneticGO:00400291470.034
Fly
ribonucleoside triphosphate metabolic processGO:00091993560.033
regulation of phosphorus metabolic processGO:00511742300.032
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092073270.032
positive regulation of nucleobase containing compound metabolic processGO:00459354090.032
Mouse
response to unfolded proteinGO:0006986290.032
oxidation reduction processGO:00551143530.031
protein complex biogenesisGO:00702713140.031
regulation of phosphate metabolic processGO:00192202300.031
Mouse
ribosomal subunit export from nucleusGO:0000054460.030
maintenance of location in cellGO:0051651580.030
Human
karyogamy involved in conjugation with cellular fusionGO:0000742150.030
negative regulation of cellular component organizationGO:00511291090.030
meiotic nuclear divisionGO:00071261630.029
regulation of cellular localizationGO:0060341500.029
regulation of transportGO:0051049850.028
karyogamyGO:0000741170.028
regulation of hydrolase activityGO:00513361330.028
Mouse
cellular response to chemical stimulusGO:00708873150.028
Mouse Rat Worm
response to abiotic stimulusGO:00096281590.028
ribonucleoside monophosphate metabolic processGO:00091612650.027
purine ribonucleoside monophosphate catabolic processGO:00091692240.027
protein complex assemblyGO:00064613020.027
ribonucleoside triphosphate catabolic processGO:00092033270.027
protein import into mitochondrial matrixGO:0030150200.026
organelle fusionGO:0048284850.026
aromatic compound catabolic processGO:00194394910.025
carbohydrate biosynthetic processGO:0016051820.025
regulation of purine nucleotide catabolic processGO:00331211060.024
rrna containing ribonucleoprotein complex export from nucleusGO:0071428460.024
regulation of catabolic processGO:00098941990.024
metal ion homeostasisGO:0055065790.024
positive regulation of cell deathGO:001094230.023
maintenance of protein location in cellGO:0032507500.023
Human
negative regulation of cellular metabolic processGO:00313244070.023
nucleotide metabolic processGO:00091174530.023
growthGO:00400071570.023
atp catabolic processGO:00062002240.023
ribonucleoside monophosphate catabolic processGO:00091582240.022
ribonucleoprotein complex disassemblyGO:0032988110.022
cellular response to organic substanceGO:00713101590.022
Mouse Worm
positive regulation of programmed cell deathGO:004306830.022
telomere organizationGO:0032200750.022
nucleoside monophosphate catabolic processGO:00091252240.022
positive regulation of apoptotic processGO:004306530.021
conjugation with cellular fusionGO:00007471060.021
ribosome biogenesisGO:00422543350.020
cell growthGO:0016049890.020
cellular response to nutrient levelsGO:00316691440.020
Human
nuclear divisionGO:00002802630.019
negative regulation of protein modification processGO:0031400370.019
carbohydrate metabolic processGO:00059752520.019
secretion by cellGO:0032940500.019
purine nucleoside monophosphate catabolic processGO:00091282240.019
mitotic cell cycle processGO:19030472940.019
negative regulation of cellular protein metabolic processGO:0032269850.019
positive regulation of protein ubiquitinationGO:003139870.018
Mouse
carboxylic acid metabolic processGO:00197523380.018
inclusion body assemblyGO:007084110.018
guanosine containing compound metabolic processGO:19010681110.017
endoplasmic reticulum unfolded protein responseGO:0030968230.017
Mouse Worm
gtp catabolic processGO:00061841070.017
positive regulation of rna splicingGO:003312020.017
mrna metabolic processGO:00160712690.017
protein maturationGO:0051604760.017
regulation of nucleotide metabolic processGO:00061401100.016
cellular homeostasisGO:00197251380.016
organonitrogen compound biosynthetic processGO:19015663140.016
translational elongationGO:0006414320.016
mitotic cell cycleGO:00002783060.016
positive regulation of hydrolase activityGO:00513451120.016
Mouse
pyrimidine containing compound metabolic processGO:0072527370.015
establishment of ribosome localizationGO:0033753460.015
regulation of phosphorylationGO:0042325860.014
Mouse
rna catabolic processGO:00064011180.014
regulation of gtpase activityGO:0043087840.014
guanosine containing compound catabolic processGO:19010691090.014
purine ribonucleoside monophosphate metabolic processGO:00091672620.013
ribonucleoprotein complex localizationGO:0071166460.013
regulation of purine nucleotide metabolic processGO:19005421090.013
chemical homeostasisGO:00488781370.013
peptidyl amino acid modificationGO:00181931160.013
ion homeostasisGO:00508011180.013
meiotic cell cycleGO:00513212720.013
generation of precursor metabolites and energyGO:00060911470.013
negative regulation of macromolecule biosynthetic processGO:00105582910.013
posttranslational protein targeting to membrane translocationGO:003120490.013
negative regulation of nitrogen compound metabolic processGO:00511723000.012
autophagyGO:00069141060.012
er nucleus signaling pathwayGO:0006984230.012
Mouse Worm
establishment of organelle localizationGO:0051656960.012
response to organic cyclic compoundGO:001407010.012
single organism membrane buddingGO:1902591210.012
regulation of cellular catabolic processGO:00313291950.012
organophosphate biosynthetic processGO:00904071820.012
membrane buddingGO:0006900220.012
single organism developmental processGO:00447672580.012
Human Mouse Worm
negative regulation of transcription dna templatedGO:00458922580.012
regulation of signal transductionGO:00099661140.011
Mouse
atp metabolic processGO:00460342510.011
response to toxic substanceGO:000963690.011
Rat
transition metal ion homeostasisGO:0055076590.011
negative regulation of gene expressionGO:00106293120.011
Fly
purine nucleoside monophosphate metabolic processGO:00091262620.011
conjugationGO:00007461070.011
cellular response to unfolded proteinGO:0034620230.011
Mouse Worm
negative regulation of nucleic acid templated transcriptionGO:19035072600.011
macromolecule methylationGO:0043414850.011
cellular ion homeostasisGO:00068731120.011
cellular developmental processGO:00488691910.011
telomere maintenanceGO:0000723740.011
regulation of rna splicingGO:004348430.011
protein complex disassemblyGO:0043241700.011
response to temperature stimulusGO:0009266740.011
regulation of signalingGO:00230511190.010
Mouse
mrna processingGO:00063971850.010
cellular protein complex disassemblyGO:0043624420.010
ion transmembrane transportGO:00342202000.010
cellular response to heatGO:0034605530.010
response to uvGO:000941140.010
positive regulation of signalingGO:0023056200.010
negative regulation of protein metabolic processGO:0051248850.010

KAR2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012