IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

37 known processes

MDM20 (YOL076W)

Mdm20p

(Aliases: DEC1,NAA25)

SGD: S000005436
Entrez: 854079
UniProtKB: Q12387

Process Predictions
Disease Predictions

MDM20 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
establishment of protein localization	GO:0045184	367	0.778
cell communication	GO:0007154	345	0.431
developmental process	GO:0032502	261	0.430
cytoskeleton organization	GO:0007010	230	0.388
protein targeting	GO:0006605	272	0.318
protein transport	GO:0015031	345	0.302
cellular response to dna damage stimulus	GO:0006974	287	0.289
peptidyl amino acid modification	GO:0018193	116	0.261
cellular amino acid metabolic process	GO:0006520	225	0.229
regulation of biological quality	GO:0065008	391	0.197
regulation of chromosome organization	GO:0033044	66	0.176
mitotic cell cycle process	GO:1903047	294	0.171
oxoacid metabolic process	GO:0043436	351	0.164
dna repair	GO:0006281	236	0.160
mitotic cell cycle	GO:0000278	306	0.152
establishment of protein localization to organelle	GO:0072594	278	0.149
organelle inheritance	GO:0048308	51	0.147
single organism signaling	GO:0044700	208	0.146
carboxylic acid metabolic process	GO:0019752	338	0.138
organic acid metabolic process	GO:0006082	352	0.133
histone modification	GO:0016570	119	0.124
membrane organization	GO:0061024	276	0.121
signaling	GO:0023052	208	0.121
signal transduction	GO:0007165	208	0.120
negative regulation of organelle organization	GO:0010639	103	0.118
small molecule biosynthetic process	GO:0044283	258	0.116
golgi vesicle transport	GO:0048193	188	0.110
protein localization to organelle	GO:0033365	337	0.109
single organism developmental process	GO:0044767	258	0.108
organelle fission	GO:0048285	272	0.108
intracellular protein transport	GO:0006886	319	0.108
regulation of cellular component organization	GO:0051128	334	0.107
negative regulation of cellular component organization	GO:0051129	109	0.105
chromosome segregation	GO:0007059	159	0.093
response to extracellular stimulus	GO:0009991	156	0.093
organelle localization	GO:0051640	128	0.089
regulation of organelle organization	GO:0033043	243	0.088
chemical homeostasis	GO:0048878	137	0.086
cellular response to external stimulus	GO:0071496	150	0.086
mitochondrion organization	GO:0007005	261	0.085
histone acetylation	GO:0016573	51	0.083
response to chemical	GO:0042221	390	0.083
single organism cellular localization	GO:1902580	375	0.082
mitotic cytokinesis site selection	GO:1902408	35	0.080
mrna metabolic process	GO:0016071	269	0.080
mitotic cell cycle phase transition	GO:0044772	141	0.080
regulation of chromatin modification	GO:1903308	23	0.078
negative regulation of cell cycle phase transition	GO:1901988	59	0.077
double strand break repair	GO:0006302	105	0.073
maintenance of location in cell	GO:0051651	58	0.072
protein complex assembly	GO:0006461	302	0.070
maintenance of location	GO:0051235	66	0.067
cellular response to oxygen containing compound	GO:1901701	43	0.067
macromolecule catabolic process	GO:0009057	383	0.067
regulation of signal transduction	GO:0009966	114	0.066
single organism catabolic process	GO:0044712	619	0.065
phosphorylation	GO:0016310	291	0.064
cellular homeostasis	GO:0019725	138	0.064
vesicle organization	GO:0016050	68	0.063
cytokinesis site selection	GO:0007105	40	0.063
protein complex biogenesis	GO:0070271	314	0.062
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.061
single organism membrane organization	GO:0044802	275	0.061
macromolecular complex disassembly	GO:0032984	80	0.060
negative regulation of nuclear division	GO:0051784	62	0.060
regulation of cell communication	GO:0010646	124	0.058
regulation of histone modification	GO:0031056	18	0.057
chromatin organization	GO:0006325	242	0.056
negative regulation of chromosome organization	GO:2001251	39	0.055
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.055
ubiquitin dependent protein catabolic process	GO:0006511	181	0.054
internal peptidyl lysine acetylation	GO:0018393	52	0.054
maintenance of protein location	GO:0045185	53	0.054
cellular protein complex assembly	GO:0043623	209	0.053
spindle checkpoint	GO:0031577	35	0.052
protein processing	GO:0016485	64	0.051
regulation of chromosome segregation	GO:0051983	44	0.051
protein localization to endoplasmic reticulum	GO:0070972	47	0.050
carboxylic acid biosynthetic process	GO:0046394	152	0.050
response to external stimulus	GO:0009605	158	0.050
regulation of cellular component biogenesis	GO:0044087	112	0.049
establishment or maintenance of cell polarity	GO:0007163	96	0.049
protein acylation	GO:0043543	66	0.049
negative regulation of cell division	GO:0051782	66	0.048
macromolecule methylation	GO:0043414	85	0.048
cellular macromolecule catabolic process	GO:0044265	363	0.048
regulation of signaling	GO:0023051	119	0.047
sister chromatid segregation	GO:0000819	93	0.047
response to starvation	GO:0042594	96	0.047
regulation of response to stimulus	GO:0048583	157	0.046
regulation of mitosis	GO:0007088	65	0.046
protein maturation	GO:0051604	76	0.045
cellular bud site selection	GO:0000282	35	0.044
peptidyl lysine acetylation	GO:0018394	52	0.044
dna templated transcription elongation	GO:0006354	91	0.043
nuclear division	GO:0000280	263	0.042
protein catabolic process	GO:0030163	221	0.042
protein phosphorylation	GO:0006468	197	0.041
maintenance of protein location in cell	GO:0032507	50	0.041
regulation of cellular amino acid metabolic process	GO:0006521	16	0.040
vacuolar transport	GO:0007034	145	0.040
intracellular signal transduction	GO:0035556	112	0.039
protein localization to membrane	GO:0072657	102	0.039
cellular component disassembly	GO:0022411	86	0.038
cellular response to organic substance	GO:0071310	159	0.038
cellular nitrogen compound catabolic process	GO:0044270	494	0.038
cellular response to chemical stimulus	GO:0070887	315	0.038
cytokinetic process	GO:0032506	78	0.038
actin cytoskeleton organization	GO:0030036	100	0.037
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.037
peptidyl lysine modification	GO:0018205	77	0.037
protein targeting to membrane	GO:0006612	52	0.037
response to uv	GO:0009411	4	0.035
mitotic nuclear division	GO:0007067	131	0.035
cellular ketone metabolic process	GO:0042180	63	0.035
modification dependent protein catabolic process	GO:0019941	181	0.035
cell division	GO:0051301	205	0.035
regulation of protein localization	GO:0032880	62	0.034
amine metabolic process	GO:0009308	51	0.034
cellular response to nutrient levels	GO:0031669	144	0.034
translation	GO:0006412	230	0.033
anatomical structure development	GO:0048856	160	0.033
cellular developmental process	GO:0048869	191	0.033
mrna 3 end processing	GO:0031124	54	0.032
vacuole organization	GO:0007033	75	0.032
protein acetylation	GO:0006473	59	0.032
regulation of protein metabolic process	GO:0051246	237	0.032
nucleobase containing compound catabolic process	GO:0034655	479	0.031
negative regulation of cell cycle	GO:0045786	91	0.031
protein complex disassembly	GO:0043241	70	0.031
mrna processing	GO:0006397	185	0.031
proteolysis	GO:0006508	268	0.031
macroautophagy	GO:0016236	55	0.031
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	38	0.031
regulation of cellular ketone metabolic process	GO:0010565	42	0.030
regulation of chromatin organization	GO:1902275	23	0.030
proteasomal protein catabolic process	GO:0010498	141	0.030
regulation of localization	GO:0032879	127	0.030
positive regulation of organelle organization	GO:0010638	85	0.029
vesicle mediated transport	GO:0016192	335	0.029
regulation of phosphate metabolic process	GO:0019220	230	0.029
homeostatic process	GO:0042592	227	0.029
cell cycle phase transition	GO:0044770	144	0.029
endosomal transport	GO:0016197	86	0.029
purine nucleoside metabolic process	GO:0042278	380	0.029
developmental process involved in reproduction	GO:0003006	159	0.029
positive regulation of biosynthetic process	GO:0009891	336	0.029
regulation of catabolic process	GO:0009894	199	0.028
nucleoside metabolic process	GO:0009116	394	0.028
transcription elongation from rna polymerase ii promoter	GO:0006368	81	0.028
establishment of protein localization to membrane	GO:0090150	99	0.027
positive regulation of rna biosynthetic process	GO:1902680	286	0.027
negative regulation of gene expression	GO:0010629	312	0.027
dna conformation change	GO:0071103	98	0.026
protein alkylation	GO:0008213	48	0.026
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	137	0.025
organonitrogen compound biosynthetic process	GO:1901566	314	0.025
aging	GO:0007568	71	0.025
regulation of cellular protein metabolic process	GO:0032268	232	0.025
purine nucleotide metabolic process	GO:0006163	376	0.025
chromosome localization	GO:0050000	20	0.024
negative regulation of protein depolymerization	GO:1901880	12	0.024
single organism reproductive process	GO:0044702	159	0.024
cellular protein catabolic process	GO:0044257	213	0.023
response to oxygen containing compound	GO:1901700	61	0.022
apoptotic process	GO:0006915	30	0.022
cell differentiation	GO:0030154	161	0.022
heterocycle catabolic process	GO:0046700	494	0.022
cellular amine metabolic process	GO:0044106	51	0.022
conjugation with cellular fusion	GO:0000747	106	0.022
multi organism cellular process	GO:0044764	120	0.022
mrna catabolic process	GO:0006402	93	0.022
actin filament based process	GO:0030029	104	0.022
methylation	GO:0032259	101	0.022
dna recombination	GO:0006310	172	0.022
negative regulation of protein processing	GO:0010955	33	0.021
ribonucleoside metabolic process	GO:0009119	389	0.021
regulation of cytoskeleton organization	GO:0051493	63	0.021
ribose phosphate metabolic process	GO:0019693	384	0.021
termination of rna polymerase ii transcription	GO:0006369	26	0.021
posttranscriptional regulation of gene expression	GO:0010608	115	0.021
covalent chromatin modification	GO:0016569	119	0.021
mitotic sister chromatid segregation	GO:0000070	85	0.021
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	40	0.020
purine nucleotide catabolic process	GO:0006195	328	0.020
nuclear transcribed mrna catabolic process deadenylation dependent decay	GO:0000288	44	0.020
cellular response to starvation	GO:0009267	90	0.020
positive regulation of transcription dna templated	GO:0045893	286	0.020
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.020
regulation of cell wall organization or biogenesis	GO:1903338	18	0.020
positive regulation of cell cycle process	GO:0090068	31	0.020
positive regulation of protein modification process	GO:0031401	49	0.020
nucleoside triphosphate metabolic process	GO:0009141	364	0.020
cellular response to extracellular stimulus	GO:0031668	150	0.020
reproductive process	GO:0022414	248	0.020
nucleoside phosphate metabolic process	GO:0006753	458	0.020
cellular chemical homeostasis	GO:0055082	123	0.020
cell cycle checkpoint	GO:0000075	82	0.020
response to pheromone involved in conjugation with cellular fusion	GO:0000749	74	0.019
carbohydrate biosynthetic process	GO:0016051	82	0.019
purine ribonucleotide metabolic process	GO:0009150	372	0.019
regulation of dna templated transcription elongation	GO:0032784	44	0.019
meiotic cell cycle process	GO:1903046	229	0.019
response to nutrient levels	GO:0031667	150	0.019
cell aging	GO:0007569	70	0.019
meiotic nuclear division	GO:0007126	163	0.018
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.018
ion homeostasis	GO:0050801	118	0.018
chromatin assembly	GO:0031497	35	0.018
phospholipid metabolic process	GO:0006644	125	0.017
mating type determination	GO:0007531	32	0.017
cellular amino acid catabolic process	GO:0009063	48	0.017
establishment of organelle localization	GO:0051656	96	0.017
endocytosis	GO:0006897	90	0.017
protein import into nucleus	GO:0006606	55	0.017
regulation of cellular catabolic process	GO:0031329	195	0.017
establishment of cell polarity	GO:0030010	64	0.017
negative regulation of protein metabolic process	GO:0051248	85	0.017
cellular component morphogenesis	GO:0032989	97	0.017
nuclear transcribed mrna catabolic process	GO:0000956	89	0.017
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.017
positive regulation of secretion	GO:0051047	2	0.017
modification dependent macromolecule catabolic process	GO:0043632	203	0.016
positive regulation of gene expression	GO:0010628	321	0.016
positive regulation of cellular component organization	GO:0051130	116	0.016
positive regulation of cell cycle	GO:0045787	32	0.016
organonitrogen compound catabolic process	GO:1901565	404	0.016
organelle fusion	GO:0048284	85	0.016
dna templated transcription termination	GO:0006353	42	0.016
meiotic cell cycle	GO:0051321	272	0.016
response to abiotic stimulus	GO:0009628	159	0.016
negative regulation of cellular protein metabolic process	GO:0032269	85	0.016
negative regulation of cellular metabolic process	GO:0031324	407	0.016
ribonucleotide metabolic process	GO:0009259	377	0.016
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.015
response to inorganic substance	GO:0010035	47	0.015
growth	GO:0040007	157	0.015
meiosis i	GO:0007127	92	0.015
response to organic cyclic compound	GO:0014070	1	0.015
positive regulation of intracellular protein transport	GO:0090316	3	0.015
dna packaging	GO:0006323	55	0.015
regulation of anatomical structure size	GO:0090066	50	0.015
negative regulation of mitotic cell cycle	GO:0045930	63	0.015
negative regulation of signal transduction	GO:0009968	30	0.015
chromatin remodeling	GO:0006338	80	0.014
sexual reproduction	GO:0019953	216	0.014
post golgi vesicle mediated transport	GO:0006892	72	0.014
positive regulation of macromolecule metabolic process	GO:0010604	394	0.014
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.014
organic cyclic compound catabolic process	GO:1901361	499	0.014
mitotic spindle checkpoint	GO:0071174	34	0.014
organophosphate metabolic process	GO:0019637	597	0.014
regulation of cellular localization	GO:0060341	50	0.013
internal protein amino acid acetylation	GO:0006475	52	0.013
cellular lipid metabolic process	GO:0044255	229	0.013
positive regulation of chromosome organization	GO:2001252	20	0.013
response to hypoxia	GO:0001666	4	0.013
mitotic cytokinetic process	GO:1902410	45	0.013
programmed cell death	GO:0012501	30	0.013
cellular ion homeostasis	GO:0006873	112	0.013
carbohydrate derivative metabolic process	GO:1901135	549	0.013
asexual reproduction	GO:0019954	48	0.013
carbohydrate derivative catabolic process	GO:1901136	339	0.013
ribonucleotide catabolic process	GO:0009261	327	0.013
negative regulation of protein maturation	GO:1903318	33	0.013
dephosphorylation	GO:0016311	127	0.013
aromatic compound catabolic process	GO:0019439	491	0.013
purine ribonucleotide catabolic process	GO:0009154	327	0.013
regulation of transport	GO:0051049	85	0.013
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.013
cellular component assembly involved in morphogenesis	GO:0010927	73	0.013
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.013
er to golgi vesicle mediated transport	GO:0006888	86	0.013
positive regulation of secretion by cell	GO:1903532	2	0.013
regulation of cell cycle process	GO:0010564	150	0.013
cellular protein complex disassembly	GO:0043624	42	0.012
organic acid biosynthetic process	GO:0016053	152	0.012
multi organism reproductive process	GO:0044703	216	0.012
regulation of intracellular transport	GO:0032386	26	0.012
protein methylation	GO:0006479	48	0.012
carbohydrate metabolic process	GO:0005975	252	0.012
mitotic cytokinesis	GO:0000281	58	0.012
regulation of carbohydrate biosynthetic process	GO:0043255	31	0.012
ras protein signal transduction	GO:0007265	29	0.012
atp dependent chromatin remodeling	GO:0043044	36	0.012
lipid localization	GO:0010876	60	0.012
organophosphate catabolic process	GO:0046434	338	0.012
protein transmembrane transport	GO:0071806	82	0.012
positive regulation of cellular biosynthetic process	GO:0031328	336	0.012
regulation of cellular amine metabolic process	GO:0033238	21	0.012
actin filament organization	GO:0007015	56	0.012
organic hydroxy compound metabolic process	GO:1901615	125	0.012
purine nucleoside catabolic process	GO:0006152	330	0.012
regulation of translation	GO:0006417	89	0.012
response to pheromone	GO:0019236	92	0.011
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	109	0.011
regulation of hydrolase activity	GO:0051336	133	0.011
lipid metabolic process	GO:0006629	269	0.011
positive regulation of apoptotic process	GO:0043065	3	0.011
glycosyl compound catabolic process	GO:1901658	335	0.011
regulation of gene expression epigenetic	GO:0040029	147	0.011
positive regulation of cell death	GO:0010942	3	0.011
purine containing compound catabolic process	GO:0072523	332	0.011
cellular polysaccharide biosynthetic process	GO:0033692	38	0.011
rrna processing	GO:0006364	227	0.011
regulation of nuclear division	GO:0051783	103	0.011
regulation of protein processing	GO:0070613	34	0.011
anatomical structure morphogenesis	GO:0009653	160	0.011
positive regulation of chromatin modification	GO:1903310	13	0.011
regulation of dna dependent dna replication	GO:0090329	37	0.011
purine nucleoside monophosphate metabolic process	GO:0009126	262	0.011
cell death	GO:0008219	30	0.011
positive regulation of molecular function	GO:0044093	185	0.011
vacuole inheritance	GO:0000011	16	0.011
replicative cell aging	GO:0001302	46	0.010
response to organic substance	GO:0010033	182	0.010
cation transport	GO:0006812	166	0.010
nucleoside triphosphate catabolic process	GO:0009143	329	0.010
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.010
reproduction of a single celled organism	GO:0032505	191	0.010
positive regulation of response to stimulus	GO:0048584	37	0.010
mitotic cell cycle checkpoint	GO:0007093	56	0.010
regulation of protein transport	GO:0051223	17	0.010
cellular glucan metabolic process	GO:0006073	44	0.010
positive regulation of protein metabolic process	GO:0051247	93	0.010
positive regulation of cellular catabolic process	GO:0031331	128	0.010
protein ubiquitination	GO:0016567	118	0.010
negative regulation of cellular biosynthetic process	GO:0031327	312	0.010
microtubule anchoring	GO:0034453	25	0.010

MDM20 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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