IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

121 known processes

EPL1 (YFL024C)

Epl1p

SGD: S000001870
Entrez: 850520
UniProtKB: P43572

Process Predictions
Disease Predictions

EPL1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
histone modification	GO:0016570	119	0.978
chromatin modification	GO:0016568	200	0.964
protein acylation	GO:0043543	66	0.956
dna repair	GO:0006281	236	0.942
histone acetylation	GO:0016573	51	0.933
peptidyl lysine modification	GO:0018205	77	0.924
chromatin organization	GO:0006325	242	0.911
histone exchange	GO:0043486	18	0.907
covalent chromatin modification	GO:0016569	119	0.901
peptidyl lysine acetylation	GO:0018394	52	0.898
atp dependent chromatin remodeling	GO:0043044	36	0.843
chromatin remodeling	GO:0006338	80	0.832
internal peptidyl lysine acetylation	GO:0018393	52	0.828
internal protein amino acid acetylation	GO:0006475	52	0.817
peptidyl amino acid modification	GO:0018193	116	0.749
cellular response to dna damage stimulus	GO:0006974	287	0.737
nucleosome organization	GO:0034728	63	0.663
protein acetylation	GO:0006473	59	0.609
double strand break repair	GO:0006302	105	0.387
protein dna complex subunit organization	GO:0071824	153	0.308
chromatin silencing at telomere	GO:0006348	84	0.285
anatomical structure morphogenesis	GO:0009653	160	0.248
microtubule based process	GO:0007017	117	0.241
histone deacetylation	GO:0016575	26	0.216
negative regulation of rna metabolic process	GO:0051253	262	0.208
chromatin silencing	GO:0006342	147	0.196
negative regulation of gene expression	GO:0010629	312	0.185
negative regulation of gene expression epigenetic	GO:0045814	147	0.183
negative regulation of rna biosynthetic process	GO:1902679	260	0.179
transcription elongation from rna polymerase ii promoter	GO:0006368	81	0.167
negative regulation of transcription dna templated	GO:0045892	258	0.159
single organism catabolic process	GO:0044712	619	0.155
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.151
negative regulation of cellular biosynthetic process	GO:0031327	312	0.149
developmental process	GO:0032502	261	0.144
cellular developmental process	GO:0048869	191	0.142
negative regulation of cellular metabolic process	GO:0031324	407	0.142
regulation of gene expression epigenetic	GO:0040029	147	0.124
signaling	GO:0023052	208	0.121
protein complex assembly	GO:0006461	302	0.116
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.104
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	40	0.103
dna templated transcription elongation	GO:0006354	91	0.094
regulation of cell communication	GO:0010646	124	0.092
regulation of chromatin silencing	GO:0031935	39	0.087
single organism developmental process	GO:0044767	258	0.083
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.081
response to starvation	GO:0042594	96	0.080
negative regulation of macromolecule metabolic process	GO:0010605	375	0.080
cell cycle phase transition	GO:0044770	144	0.077
positive regulation of macromolecule metabolic process	GO:0010604	394	0.076
protein complex biogenesis	GO:0070271	314	0.075
anatomical structure development	GO:0048856	160	0.075
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	38	0.070
chromatin silencing at silent mating type cassette	GO:0030466	53	0.070
cellular protein complex assembly	GO:0043623	209	0.067
response to chemical	GO:0042221	390	0.065
regulation of cellular catabolic process	GO:0031329	195	0.064
positive regulation of cell death	GO:0010942	3	0.063
microtubule cytoskeleton organization	GO:0000226	109	0.060
regulation of cellular protein metabolic process	GO:0032268	232	0.059
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.058
response to organic substance	GO:0010033	182	0.056
nuclear import	GO:0051170	57	0.056
regulation of protein metabolic process	GO:0051246	237	0.053
gene silencing	GO:0016458	151	0.048
response to oxidative stress	GO:0006979	99	0.048
cellular response to nutrient levels	GO:0031669	144	0.047
nucleoside phosphate metabolic process	GO:0006753	458	0.047
response to oxygen containing compound	GO:1901700	61	0.046
positive regulation of gene expression	GO:0010628	321	0.046
single organism signaling	GO:0044700	208	0.046
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.045
positive regulation of apoptotic process	GO:0043065	3	0.044
positive regulation of cell communication	GO:0010647	28	0.044
positive regulation of response to stimulus	GO:0048584	37	0.043
regulation of histone exchange	GO:1900049	4	0.043
positive regulation of cellular component organization	GO:0051130	116	0.043
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.043
establishment of protein localization	GO:0045184	367	0.043
cellular response to extracellular stimulus	GO:0031668	150	0.043
cellular response to starvation	GO:0009267	90	0.042
protein targeting to nucleus	GO:0044744	57	0.042
double strand break repair via nonhomologous end joining	GO:0006303	27	0.042
non recombinational repair	GO:0000726	33	0.041
alpha amino acid metabolic process	GO:1901605	124	0.041
endocytosis	GO:0006897	90	0.041
cellular response to external stimulus	GO:0071496	150	0.041
intracellular signal transduction	GO:0035556	112	0.040
positive regulation of rna biosynthetic process	GO:1902680	286	0.039
regulation of cell cycle	GO:0051726	195	0.039
regulation of mitotic sister chromatid segregation	GO:0033047	30	0.039
cell fate commitment	GO:0045165	32	0.039
regulation of signal transduction	GO:0009966	114	0.038
organophosphate metabolic process	GO:0019637	597	0.038
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.038
nuclear transport	GO:0051169	165	0.036
sex determination	GO:0007530	32	0.036
cell communication	GO:0007154	345	0.036
rrna metabolic process	GO:0016072	244	0.036
positive regulation of cellular biosynthetic process	GO:0031328	336	0.035
positive regulation of biosynthetic process	GO:0009891	336	0.035
signal transduction	GO:0007165	208	0.035
autophagy	GO:0006914	106	0.035
response to nutrient levels	GO:0031667	150	0.034
macromolecular complex disassembly	GO:0032984	80	0.034
positive regulation of cellular protein metabolic process	GO:0032270	89	0.034
protein localization to nucleus	GO:0034504	74	0.034
growth	GO:0040007	157	0.033
regulation of biological quality	GO:0065008	391	0.033
regulation of dna templated transcription elongation	GO:0032784	44	0.032
positive regulation of programmed cell death	GO:0043068	3	0.032
regulation of catabolic process	GO:0009894	199	0.032
mitotic cell cycle phase transition	GO:0044772	141	0.031
nucleocytoplasmic transport	GO:0006913	163	0.029
protein complex disassembly	GO:0043241	70	0.029
histone h3 acetylation	GO:0043966	5	0.028
regulation of mitotic sister chromatid separation	GO:0010965	29	0.028
mitotic cell cycle checkpoint	GO:0007093	56	0.028
reproduction of a single celled organism	GO:0032505	191	0.028
regulation of gene silencing	GO:0060968	41	0.027
actin filament based process	GO:0030029	104	0.027
ion transport	GO:0006811	274	0.026
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	137	0.026
homeostatic process	GO:0042592	227	0.026
negative regulation of biosynthetic process	GO:0009890	312	0.026
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.025
positive regulation of protein metabolic process	GO:0051247	93	0.025
regulation of autophagy	GO:0010506	18	0.025
nucleobase containing small molecule metabolic process	GO:0055086	491	0.025
regulation of chromatin silencing at silent mating type cassette	GO:0090054	13	0.025
regulation of transcription by chromatin organization	GO:0034401	19	0.025
regulation of hydrolase activity	GO:0051336	133	0.025
negative regulation of chromatin silencing	GO:0031936	25	0.024
dna dependent dna replication	GO:0006261	115	0.024
protein deacetylation	GO:0006476	26	0.023
protein transport	GO:0015031	345	0.023
proteolysis	GO:0006508	268	0.023
cellular response to chemical stimulus	GO:0070887	315	0.023
organonitrogen compound catabolic process	GO:1901565	404	0.023
regulation of transcription factor import into nucleus	GO:0042990	4	0.023
positive regulation of rna metabolic process	GO:0051254	294	0.023
aging	GO:0007568	71	0.023
establishment of organelle localization	GO:0051656	96	0.023
regulation of signaling	GO:0023051	119	0.022
macroautophagy	GO:0016236	55	0.022
regulation of cellular localization	GO:0060341	50	0.022
response to extracellular stimulus	GO:0009991	156	0.022
negative regulation of cell cycle	GO:0045786	91	0.021
chromosome separation	GO:0051304	33	0.021
regulation of response to stimulus	GO:0048583	157	0.021
positive regulation of protein localization to nucleus	GO:1900182	7	0.021
cellular nitrogen compound catabolic process	GO:0044270	494	0.021
chromatin disassembly	GO:0031498	19	0.021
macromolecule deacylation	GO:0098732	27	0.021
regulation of macroautophagy	GO:0016241	15	0.021
regulation of cellular response to stress	GO:0080135	50	0.021
nucleoside monophosphate metabolic process	GO:0009123	267	0.021
single organism carbohydrate metabolic process	GO:0044723	237	0.021
regulation of dna replication	GO:0006275	51	0.020
regulation of cellular component organization	GO:0051128	334	0.020
microtubule organizing center organization	GO:0031023	33	0.020
ascospore formation	GO:0030437	107	0.020
cytoskeleton organization	GO:0007010	230	0.019
reproductive process in single celled organism	GO:0022413	145	0.019
positive regulation of dna templated transcription elongation	GO:0032786	42	0.019
positive regulation of transcription dna templated	GO:0045893	286	0.019
negative regulation of cell cycle process	GO:0010948	86	0.018
multi organism reproductive process	GO:0044703	216	0.018
establishment of protein localization to organelle	GO:0072594	278	0.018
oxidation reduction process	GO:0055114	353	0.018
negative regulation of cellular component organization	GO:0051129	109	0.018
regulation of response to stress	GO:0080134	57	0.018
positive regulation of cellular catabolic process	GO:0031331	128	0.017
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.017
conjugation with cellular fusion	GO:0000747	106	0.017
positive regulation of signaling	GO:0023056	20	0.017
maintenance of protein location	GO:0045185	53	0.017
negative regulation of cellular response to alkaline ph by negative regulation of transcription from rna polymerase ii promoter	GO:1900463	1	0.017
vesicle mediated transport	GO:0016192	335	0.017
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.017
regulation of chromatin organization	GO:1902275	23	0.017
regulation of dna metabolic process	GO:0051052	100	0.017
regulation of organelle organization	GO:0033043	243	0.017
positive regulation of cellular response to drug	GO:2001040	3	0.016
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.016
cellular protein catabolic process	GO:0044257	213	0.016
organic acid catabolic process	GO:0016054	71	0.016
developmental process involved in reproduction	GO:0003006	159	0.016
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.016
membrane docking	GO:0022406	22	0.016
cellular lipid metabolic process	GO:0044255	229	0.016
cell cycle checkpoint	GO:0000075	82	0.016
nitrogen compound transport	GO:0071705	212	0.016
actin cytoskeleton organization	GO:0030036	100	0.016
double strand break repair via homologous recombination	GO:0000724	54	0.016
protein import into nucleus	GO:0006606	55	0.016
response to endogenous stimulus	GO:0009719	26	0.016
protein import	GO:0017038	122	0.016
aromatic compound catabolic process	GO:0019439	491	0.015
protein modification by small protein conjugation or removal	GO:0070647	172	0.015
recombinational repair	GO:0000725	64	0.015
regulation of dna dependent dna replication	GO:0090329	37	0.015
positive regulation of transcription on exit from mitosis	GO:0007072	1	0.015
cell differentiation	GO:0030154	161	0.015
nucleotide metabolic process	GO:0009117	453	0.015
mitotic cell cycle process	GO:1903047	294	0.015
protein modification by small protein removal	GO:0070646	29	0.015
positive regulation of intracellular protein transport	GO:0090316	3	0.015
negative regulation of chromatin silencing at telomere	GO:0031939	15	0.015
sexual reproduction	GO:0019953	216	0.015
mitochondrion organization	GO:0007005	261	0.014
sporulation	GO:0043934	132	0.014
surface biofilm formation	GO:0090604	3	0.014
dna replication initiation	GO:0006270	48	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.014
protein deacylation	GO:0035601	27	0.014
regulation of nucleoside metabolic process	GO:0009118	106	0.014
organonitrogen compound biosynthetic process	GO:1901566	314	0.014
heterochromatin organization	GO:0070828	11	0.014
negative regulation of organelle organization	GO:0010639	103	0.014
organic acid metabolic process	GO:0006082	352	0.014
nucleobase containing compound catabolic process	GO:0034655	479	0.014
transfer rna gene mediated silencing	GO:0061587	14	0.013
regulation of cellular component biogenesis	GO:0044087	112	0.013
metaphase anaphase transition of cell cycle	GO:0044784	28	0.013
single organism reproductive process	GO:0044702	159	0.013
positive regulation of signal transduction	GO:0009967	20	0.013
regulation of response to nutrient levels	GO:0032107	20	0.013
lipid metabolic process	GO:0006629	269	0.013
protein localization to chromosome	GO:0034502	28	0.013
mating type switching	GO:0007533	28	0.012
chemical homeostasis	GO:0048878	137	0.012
conjugation	GO:0000746	107	0.012
positive regulation of catabolic process	GO:0009896	135	0.012
protein deubiquitination	GO:0016579	17	0.012
positive regulation of transcription by oleic acid	GO:0061421	4	0.012
regulation of chromatin silencing at telomere	GO:0031938	27	0.012
posttranscriptional regulation of gene expression	GO:0010608	115	0.012
positive regulation of organelle organization	GO:0010638	85	0.012
positive regulation of transport	GO:0051050	32	0.012
mitotic cell cycle	GO:0000278	306	0.012
single organism nuclear import	GO:1902593	56	0.012
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.012
nuclear export	GO:0051168	124	0.012
positive regulation of translation	GO:0045727	34	0.012
positive regulation of ethanol catabolic process	GO:1900066	1	0.012
negative regulation of cell division	GO:0051782	66	0.012
regulation of nucleotide catabolic process	GO:0030811	106	0.012
positive regulation of nucleoside metabolic process	GO:0045979	97	0.012
regulation of response to extracellular stimulus	GO:0032104	20	0.012
maintenance of protein location in cell	GO:0032507	50	0.012
macromolecule catabolic process	GO:0009057	383	0.011
regulation of intracellular transport	GO:0032386	26	0.011
purine ribonucleoside monophosphate catabolic process	GO:0009169	224	0.011
trna metabolic process	GO:0006399	151	0.011
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.011
meiotic cell cycle process	GO:1903046	229	0.011
replicative cell aging	GO:0001302	46	0.011
regulation of molecular function	GO:0065009	320	0.011
cell death	GO:0008219	30	0.011
intracellular protein transport	GO:0006886	319	0.011
small molecule biosynthetic process	GO:0044283	258	0.011
response to organic cyclic compound	GO:0014070	1	0.011
ribonucleoside monophosphate catabolic process	GO:0009158	224	0.011
regulation of developmental process	GO:0050793	30	0.011
cell aging	GO:0007569	70	0.011
regulation of protein import into nucleus	GO:0042306	10	0.011
regulation of protein targeting	GO:1903533	10	0.011
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.011
cellular cation homeostasis	GO:0030003	100	0.010
maintenance of location	GO:0051235	66	0.010
negative regulation of gene silencing	GO:0060969	27	0.010
positive regulation of sulfite transport by positive regulation of transcription from rna polymerase ii promoter	GO:0061426	1	0.010
cytokinesis	GO:0000910	92	0.010
positive regulation of macroautophagy	GO:0016239	8	0.010
cell division	GO:0051301	205	0.010
multi organism process	GO:0051704	233	0.010
negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from rna polymerase ii promoter	GO:1900464	2	0.010
acetate biosynthetic process	GO:0019413	4	0.010
regulation of transcription from rna polymerase ii promoter in response to stress	GO:0043618	51	0.010
organelle inheritance	GO:0048308	51	0.010

EPL1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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