Saccharomyces cerevisiae

118 known processes

TOP1 (YOL006C)

Top1p

(Aliases: MAK17,MAK1)

TOP1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repairGO:00063021050.745
macromolecule catabolic processGO:00090573830.735
dna recombinationGO:00063101720.579
negative regulation of gene expressionGO:00106293120.426
cellular macromolecule catabolic processGO:00442653630.413
regulation of gene expression epigeneticGO:00400291470.308
nucleic acid phosphodiester bond hydrolysisGO:00903051940.291
dna conformation changeGO:0071103980.217
nucleobase containing compound catabolic processGO:00346554790.214
negative regulation of nucleobase containing compound metabolic processGO:00459342950.206
mrna metabolic processGO:00160712690.202
double strand break repair via homologous recombinationGO:0000724540.183
cellular response to dna damage stimulusGO:00069742870.160
chromatin silencingGO:00063421470.156
membrane organizationGO:00610242760.151
chromatin organizationGO:00063252420.150
single organism membrane organizationGO:00448022750.146
dna packagingGO:0006323550.141
regulation of dna metabolic processGO:00510521000.137
regulation of dna replicationGO:0006275510.134
negative regulation of nitrogen compound metabolic processGO:00511723000.115
protein catabolic processGO:00301632210.114
rna catabolic processGO:00064011180.112
chromatin assembly or disassemblyGO:0006333600.110
dna dependent dna replicationGO:00062611150.109
aromatic compound catabolic processGO:00194394910.103
cellular nitrogen compound catabolic processGO:00442704940.100
negative regulation of cellular biosynthetic processGO:00313273120.087
negative regulation of transcription dna templatedGO:00458922580.081
meiotic cell cycle processGO:19030462290.080
organic cyclic compound catabolic processGO:19013614990.079
cellular component disassemblyGO:0022411860.079
negative regulation of cellular macromolecule biosynthetic processGO:20001132890.074
sister chromatid cohesionGO:0007062490.069
mating type switchingGO:0007533280.067
negative regulation of gene expression epigeneticGO:00458141470.066
chromosome condensationGO:0030261190.065
regulation of dna dependent dna replicationGO:0090329370.065
recombinational repairGO:0000725640.062
response to extracellular stimulusGO:00099911560.061
translationGO:00064122300.061
negative regulation of cellular metabolic processGO:00313244070.060
cellular lipid metabolic processGO:00442552290.057
sex determinationGO:0007530320.056
regulation of response to dna damage stimulusGO:2001020170.056
mitotic sister chromatid segregationGO:0000070850.056
dna replication initiationGO:0006270480.054
nucleocytoplasmic transportGO:00069131630.053
double strand break repair via nonhomologous end joiningGO:0006303270.052
rrna metabolic processGO:00160722440.049
regulation of biological qualityGO:00650083910.048
autophagyGO:00069141060.047
positive regulation of gene expressionGO:00106283210.046
transcription from rna polymerase i promoterGO:0006360630.046
response to external stimulusGO:00096051580.045
negative regulation of rna metabolic processGO:00512532620.045
proteolysis involved in cellular protein catabolic processGO:00516031980.045
non recombinational repairGO:0000726330.045
heterocycle catabolic processGO:00467004940.045
negative regulation of macromolecule metabolic processGO:00106053750.045
negative regulation of macromolecule biosynthetic processGO:00105582910.045
negative regulation of biosynthetic processGO:00098903120.045
dna repairGO:00062812360.044
dna templated transcription initiationGO:0006352710.044
protein complex disassemblyGO:0043241700.044
chromatin silencing at rdnaGO:0000183320.043
dna catabolic processGO:0006308420.041
nuclear transportGO:00511691650.040
positive regulation of macromolecule biosynthetic processGO:00105573250.039
single organism cellular localizationGO:19025803750.039
negative regulation of nucleic acid templated transcriptionGO:19035072600.038
multi organism processGO:00517042330.035
gene silencingGO:00164581510.034
cellular response to external stimulusGO:00714961500.033
regulation of organelle organizationGO:00330432430.033
positive regulation of rna metabolic processGO:00512542940.031
negative regulation of cellular component organizationGO:00511291090.031
developmental process involved in reproductionGO:00030061590.031
negative regulation of cell cycleGO:0045786910.031
protein transportGO:00150313450.030
negative regulation of chromosome organizationGO:2001251390.029
rna localizationGO:00064031120.029
multi organism reproductive processGO:00447032160.029
reciprocal dna recombinationGO:0035825540.029
organelle assemblyGO:00709251180.026
cellular response to nutrient levelsGO:00316691440.026
negative regulation of rna biosynthetic processGO:19026792600.024
sexual reproductionGO:00199532160.024
cellular amine metabolic processGO:0044106510.023
response to chemicalGO:00422213900.023
Human
chromatin silencing at telomereGO:0006348840.022
nucleus organizationGO:0006997620.022
response to uvGO:000941140.022
mitotic recombinationGO:0006312550.022
amine metabolic processGO:0009308510.022
homeostatic processGO:00425922270.021
replicative cell agingGO:0001302460.020
protein ubiquitinationGO:00165671180.020
protein modification by small protein conjugationGO:00324461440.020
cell cycle phase transitionGO:00447701440.019
establishment of protein localization to organelleGO:00725942780.019
negative regulation of organelle organizationGO:00106391030.019
sister chromatid segregationGO:0000819930.019
regulation of cell cycle processGO:00105641500.019
negative regulation of dna metabolic processGO:0051053360.019
glycerolipid metabolic processGO:00464861080.019
cellular response to heatGO:0034605530.019
organophosphate metabolic processGO:00196375970.019
cellular protein complex disassemblyGO:0043624420.018
protein processingGO:0016485640.018
nuclear exportGO:00511681240.018
nitrogen compound transportGO:00717052120.018
single organism developmental processGO:00447672580.018
Mouse
protein modification by small protein conjugation or removalGO:00706471720.018
cellular ketone metabolic processGO:0042180630.017
meiotic cell cycleGO:00513212720.017
regulation of protein complex assemblyGO:0043254770.017
transcription dependent tethering of rna polymerase ii gene dna at nuclear peripheryGO:0000972190.017
cellular protein catabolic processGO:00442572130.017
regulation of dna dependent dna replication initiationGO:0030174210.017
single organism catabolic processGO:00447126190.016
reproductive process in single celled organismGO:00224131450.016
protein targetingGO:00066052720.016
regulation of cellular amine metabolic processGO:0033238210.016
positive regulation of apoptotic processGO:004306530.016
reproductive processGO:00224142480.016
mitotic cell cycleGO:00002783060.016
conjugationGO:00007461070.016
dna replicationGO:00062601470.015
cell differentiationGO:00301541610.015
gene conversionGO:0035822140.015
positive regulation of nucleic acid templated transcriptionGO:19035082860.015
chromatin silencing at silent mating type cassetteGO:0030466530.015
negative regulation of dna replicationGO:0008156150.015
response to nutrient levelsGO:00316671500.014
mating type determinationGO:0007531320.014
histone ubiquitinationGO:0016574170.014
protein maturationGO:0051604760.014
carboxylic acid metabolic processGO:00197523380.014
positive regulation of dna metabolic processGO:0051054260.013
ncrna processingGO:00344703300.013
cytoskeleton organizationGO:00070102300.013
rna 3 end processingGO:0031123880.013
negative regulation of mitotic cell cycleGO:0045930630.013
mrna catabolic processGO:0006402930.013
chromatin remodelingGO:0006338800.013
Human
macromolecular complex disassemblyGO:0032984800.013
programmed cell deathGO:0012501300.013
conjugation with cellular fusionGO:00007471060.013
cellular response to extracellular stimulusGO:00316681500.013
negative regulation of cellular carbohydrate metabolic processGO:0010677170.013
dna double strand break processingGO:000072980.012
protein complex biogenesisGO:00702713140.012
organonitrogen compound biosynthetic processGO:19015663140.012
nucleotide excision repairGO:0006289500.012
cellular response to abiotic stimulusGO:0071214620.012
chemical homeostasisGO:00488781370.012
negative regulation of cell cycle phase transitionGO:1901988590.012
nucleobase containing compound transportGO:00159311240.012
regulation of generation of precursor metabolites and energyGO:0043467230.012
posttranscriptional tethering of rna polymerase ii gene dna at nuclear peripheryGO:0000973160.011
protein dna complex assemblyGO:00650041050.011
chromosome organization involved in meiosisGO:0070192320.011
positive regulation of programmed cell deathGO:004306830.011
mrna export from nucleus in response to heat stressGO:0031990110.011
positive regulation of mitotic cell cycleGO:0045931160.011
regulation of cellular amino acid metabolic processGO:0006521160.011
generation of precursor metabolites and energyGO:00060911470.011
fungal type cell wall organizationGO:00315051450.011
positive regulation of cellular component organizationGO:00511301160.010
proteolysisGO:00065082680.010
regulation of dna templated transcription elongationGO:0032784440.010
regulation of cellular catabolic processGO:00313291950.010
microtubule cytoskeleton organizationGO:00002261090.010
chromatin assemblyGO:0031497350.010

TOP1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org