IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

130 known processes

STE4 (YOR212W)

Ste4p

(Aliases: HMD2)

SGD: S000005738
Entrez: 854387
UniProtKB: P18851

Process Predictions
Disease Predictions

STE4 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
response to pheromone	GO:0019236	92	0.998
multi organism cellular process	GO:0044764	120	0.994
multi organism reproductive process	GO:0044703	216	0.994
response to organic substance	GO:0010033	182	0.990
cellular response to pheromone	GO:0071444	88	0.987
signaling	GO:0023052	208	0.987
conjugation	GO:0000746	107	0.985
signal transduction	GO:0007165	208	0.985
multi organism process	GO:0051704	233	0.982
g protein coupled receptor signaling pathway	GO:0007186	37	0.981
reproductive process	GO:0022414	248	0.981
single organism signaling	GO:0044700	208	0.976
sexual reproduction	GO:0019953	216	0.966
conjugation with cellular fusion	GO:0000747	106	0.964
pheromone dependent signal transduction involved in conjugation with cellular fusion	GO:0000750	31	0.963
cell surface receptor signaling pathway	GO:0007166	38	0.961
cell communication	GO:0007154	345	0.954
response to pheromone involved in conjugation with cellular fusion	GO:0000749	74	0.950
cellular response to organic substance	GO:0071310	159	0.945
cellular response to chemical stimulus	GO:0070887	315	0.923
signal transduction involved in conjugation with cellular fusion	GO:0032005	31	0.919
response to chemical	GO:0042221	390	0.909
regulation of mapk cascade	GO:0043408	22	0.844
protein complex biogenesis	GO:0070271	314	0.792
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.781
protein complex assembly	GO:0006461	302	0.756
negative regulation of macromolecule metabolic process	GO:0010605	375	0.724
nucleoside triphosphate catabolic process	GO:0009143	329	0.670
vesicle mediated transport	GO:0016192	335	0.670
heterocycle catabolic process	GO:0046700	494	0.663
cellular nitrogen compound catabolic process	GO:0044270	494	0.657
microtubule cytoskeleton organization	GO:0000226	109	0.656
cellular component movement	GO:0006928	20	0.631	Zebrafish
signal transduction by phosphorylation	GO:0023014	31	0.616
purine ribonucleotide catabolic process	GO:0009154	327	0.603
regulation of catalytic activity	GO:0050790	307	0.587
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.569
meiosis i	GO:0007127	92	0.551
negative regulation of nuclear division	GO:0051784	62	0.539
protein phosphorylation	GO:0006468	197	0.532
regulation of nuclear division	GO:0051783	103	0.524
positive regulation of phosphate metabolic process	GO:0045937	147	0.509
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.506
nucleoside catabolic process	GO:0009164	335	0.503
nuclear division	GO:0000280	263	0.499
single organism catabolic process	GO:0044712	619	0.484
spindle organization	GO:0007051	37	0.469
regulation of cellular protein metabolic process	GO:0032268	232	0.465
regulation of phosphorus metabolic process	GO:0051174	230	0.449
purine nucleotide metabolic process	GO:0006163	376	0.428
ribonucleotide catabolic process	GO:0009261	327	0.424
negative regulation of gene expression epigenetic	GO:0045814	147	0.424
nucleotide catabolic process	GO:0009166	330	0.421
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.404
regulation of protein modification process	GO:0031399	110	0.402
regulation of transferase activity	GO:0051338	83	0.395
regulation of phosphorylation	GO:0042325	86	0.393
purine ribonucleoside metabolic process	GO:0046128	380	0.391
guanosine containing compound catabolic process	GO:1901069	109	0.385
aromatic compound catabolic process	GO:0019439	491	0.379
purine ribonucleoside catabolic process	GO:0046130	330	0.372
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.370
positive regulation of mapk cascade	GO:0043410	10	0.370
regulation of organelle organization	GO:0033043	243	0.369
negative regulation of cellular metabolic process	GO:0031324	407	0.364
regulation of signal transduction	GO:0009966	114	0.364	Fly
organic cyclic compound catabolic process	GO:1901361	499	0.357
cytoskeleton organization	GO:0007010	230	0.347	Fly
nucleoside phosphate catabolic process	GO:1901292	331	0.338
organonitrogen compound catabolic process	GO:1901565	404	0.336
regulation of cell communication	GO:0010646	124	0.333	Fly
cellular macromolecule catabolic process	GO:0044265	363	0.332
negative regulation of cellular biosynthetic process	GO:0031327	312	0.330
gtp catabolic process	GO:0006184	107	0.329
microtubule based process	GO:0007017	117	0.328
mitotic cell cycle process	GO:1903047	294	0.324
intracellular signal transduction	GO:0035556	112	0.320
ribonucleotide metabolic process	GO:0009259	377	0.318
positive regulation of biosynthetic process	GO:0009891	336	0.317
guanosine containing compound metabolic process	GO:1901068	111	0.316
meiotic cell cycle	GO:0051321	272	0.311
actin cytoskeleton organization	GO:0030036	100	0.308	Fly
purine nucleotide catabolic process	GO:0006195	328	0.301
negative regulation of cell division	GO:0051782	66	0.297
regulation of protein phosphorylation	GO:0001932	75	0.297
regulation of intracellular signal transduction	GO:1902531	78	0.297
gtp metabolic process	GO:0046039	107	0.292
dna recombination	GO:0006310	172	0.281
negative regulation of gene expression	GO:0010629	312	0.277
nucleobase containing compound catabolic process	GO:0034655	479	0.274
negative regulation of organelle organization	GO:0010639	103	0.269
mitotic cell cycle	GO:0000278	306	0.261
mrna catabolic process	GO:0006402	93	0.260
single organism membrane fusion	GO:0044801	71	0.259
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.259
nucleoside triphosphate metabolic process	GO:0009141	364	0.256
regulation of phosphate metabolic process	GO:0019220	230	0.249
negative regulation of cellular component organization	GO:0051129	109	0.248
regulation of meiosis	GO:0040020	42	0.244
purine containing compound catabolic process	GO:0072523	332	0.243
purine nucleoside catabolic process	GO:0006152	330	0.242
positive regulation of protein phosphorylation	GO:0001934	28	0.236
single organism developmental process	GO:0044767	258	0.235	Human Zebrafish Mouse Fly
regulation of gtpase activity	GO:0043087	84	0.234
establishment of nucleus localization	GO:0040023	22	0.232
macromolecule catabolic process	GO:0009057	383	0.227
regulation of chromosome segregation	GO:0051983	44	0.226
ribonucleoside metabolic process	GO:0009119	389	0.219
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.218
positive regulation of protein modification process	GO:0031401	49	0.216
regulation of localization	GO:0032879	127	0.215	Human
regulation of molecular function	GO:0065009	320	0.215
regulation of biological quality	GO:0065008	391	0.210	Rat
regulation of kinase activity	GO:0043549	71	0.209
developmental process	GO:0032502	261	0.208	Human Zebrafish Mouse Fly
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.205
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.205
regulation of cell cycle	GO:0051726	195	0.202
regulation of response to stress	GO:0080134	57	0.195
glycosyl compound catabolic process	GO:1901658	335	0.194
negative regulation of biosynthetic process	GO:0009890	312	0.193
organophosphate catabolic process	GO:0046434	338	0.190
meiotic nuclear division	GO:0007126	163	0.189
negative regulation of cell cycle process	GO:0010948	86	0.187
regulation of protein metabolic process	GO:0051246	237	0.187
negative regulation of catabolic process	GO:0009895	43	0.182
positive regulation of rna biosynthetic process	GO:1902680	286	0.180
negative regulation of cell communication	GO:0010648	33	0.178
phosphorylation	GO:0016310	291	0.170
positive regulation of phosphorus metabolic process	GO:0010562	147	0.165
purine nucleoside metabolic process	GO:0042278	380	0.158
positive regulation of transferase activity	GO:0051347	28	0.156
nucleobase containing small molecule metabolic process	GO:0055086	491	0.150
regulation of protein kinase activity	GO:0045859	67	0.149
cell division	GO:0051301	205	0.147	Fly
peptidyl amino acid modification	GO:0018193	116	0.146
regulation of purine nucleotide catabolic process	GO:0033121	106	0.146
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.145
positive regulation of phosphorylation	GO:0042327	33	0.143
nucleus localization	GO:0051647	22	0.139
positive regulation of protein kinase activity	GO:0045860	22	0.138
ribonucleoside catabolic process	GO:0042454	332	0.134
single organism reproductive process	GO:0044702	159	0.134
reproductive process in single celled organism	GO:0022413	145	0.134
endocytosis	GO:0006897	90	0.132
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.131
regulation of meiotic cell cycle	GO:0051445	43	0.131
regulation of nucleoside metabolic process	GO:0009118	106	0.128
negative regulation of mitosis	GO:0045839	39	0.127
regulation of catabolic process	GO:0009894	199	0.127
negative regulation of meiotic cell cycle	GO:0051447	24	0.125
regulation of gene silencing	GO:0060968	41	0.121
covalent chromatin modification	GO:0016569	119	0.120
mitotic sister chromatid separation	GO:0051306	26	0.118
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.116
nucleoside phosphate metabolic process	GO:0006753	458	0.113
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.113
intracellular protein transport	GO:0006886	319	0.108
regulation of cell division	GO:0051302	113	0.108
filamentous growth of a population of unicellular organisms	GO:0044182	109	0.107
regulation of mitotic cell cycle	GO:0007346	107	0.107
glycosyl compound metabolic process	GO:1901657	398	0.106
rna catabolic process	GO:0006401	118	0.105
membrane organization	GO:0061024	276	0.104
positive regulation of intracellular signal transduction	GO:1902533	16	0.103
establishment of organelle localization	GO:0051656	96	0.101
positive regulation of macromolecule metabolic process	GO:0010604	394	0.101
membrane fusion	GO:0061025	73	0.100
nucleoside metabolic process	GO:0009116	394	0.100
purine ribonucleotide metabolic process	GO:0009150	372	0.095
regulation of cellular component organization	GO:0051128	334	0.093
histone modification	GO:0016570	119	0.092
reproduction of a single celled organism	GO:0032505	191	0.088
regulation of cell cycle process	GO:0010564	150	0.088
negative regulation of protein metabolic process	GO:0051248	85	0.088
organelle fission	GO:0048285	272	0.088
positive regulation of rna metabolic process	GO:0051254	294	0.088
negative regulation of cell cycle	GO:0045786	91	0.085
organelle fusion	GO:0048284	85	0.083
regulation of gtp catabolic process	GO:0033124	84	0.081
adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion	GO:0000754	23	0.079
negative regulation of rna metabolic process	GO:0051253	262	0.078
mapk cascade	GO:0000165	30	0.078
regulation of purine nucleotide metabolic process	GO:1900542	109	0.078
organophosphate metabolic process	GO:0019637	597	0.078
negative regulation of cellular catabolic process	GO:0031330	43	0.078
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.077
organelle localization	GO:0051640	128	0.076
filamentous growth	GO:0030447	124	0.076
positive regulation of response to stimulus	GO:0048584	37	0.075
meiotic cell cycle process	GO:1903046	229	0.075
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.074
mrna metabolic process	GO:0016071	269	0.073
regulation of cell cycle phase transition	GO:1901987	70	0.072
positive regulation of transcription dna templated	GO:0045893	286	0.071
mitotic spindle organization	GO:0007052	30	0.070
negative regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032435	24	0.069
positive regulation of kinase activity	GO:0033674	24	0.068
regulation of mitosis	GO:0007088	65	0.067
negative regulation of chromatin silencing at telomere	GO:0031939	15	0.067
ncrna processing	GO:0034470	330	0.066
nuclear transcribed mrna catabolic process	GO:0000956	89	0.065
chromatin silencing at telomere	GO:0006348	84	0.065
chromatin silencing	GO:0006342	147	0.065
positive regulation of gene expression	GO:0010628	321	0.064
maintenance of location in cell	GO:0051651	58	0.063
regulation of nucleotide catabolic process	GO:0030811	106	0.062
ribonucleoprotein complex subunit organization	GO:0071826	152	0.062
regulation of response to stimulus	GO:0048583	157	0.062	Fly
regulation of sister chromatid segregation	GO:0033045	30	0.062
translation	GO:0006412	230	0.062
response to extracellular stimulus	GO:0009991	156	0.062
regulation of cellular catabolic process	GO:0031329	195	0.062
carbohydrate derivative metabolic process	GO:1901135	549	0.061
purine containing compound metabolic process	GO:0072521	400	0.060
nuclear export	GO:0051168	124	0.059
positive regulation of molecular function	GO:0044093	185	0.059	Fly
transmembrane transport	GO:0055085	349	0.059	Human Rat
invasive growth in response to glucose limitation	GO:0001403	61	0.058
spindle checkpoint	GO:0031577	35	0.057
negative regulation of transcription dna templated	GO:0045892	258	0.057
protein transport	GO:0015031	345	0.057
negative regulation of cellular protein metabolic process	GO:0032269	85	0.057
external encapsulating structure organization	GO:0045229	146	0.057
mitotic cell cycle checkpoint	GO:0007093	56	0.057
establishment of protein localization	GO:0045184	367	0.056
growth	GO:0040007	157	0.055
response to abiotic stimulus	GO:0009628	159	0.055	Rat Fly
single organism membrane organization	GO:0044802	275	0.055
positive regulation of purine nucleotide catabolic process	GO:0033123	97	0.054
vacuole fusion non autophagic	GO:0042144	40	0.053
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.053
reciprocal meiotic recombination	GO:0007131	54	0.052
cell development	GO:0048468	107	0.052
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.052
cell cycle checkpoint	GO:0000075	82	0.051
chromatin modification	GO:0016568	200	0.051
karyogamy	GO:0000741	17	0.051
negative regulation of signaling	GO:0023057	30	0.051
regulation of protein catabolic process	GO:0042176	40	0.050
mitotic nuclear division	GO:0007067	131	0.049
gene silencing	GO:0016458	151	0.048
anatomical structure development	GO:0048856	160	0.047	Human Zebrafish Mouse Fly
negative regulation of rna biosynthetic process	GO:1902679	260	0.047
carbohydrate derivative catabolic process	GO:1901136	339	0.047
regulation of nucleotide metabolic process	GO:0006140	110	0.046
cell differentiation	GO:0030154	161	0.046	Fly
negative regulation of protein catabolic process	GO:0042177	27	0.045
mitotic cell cycle phase transition	GO:0044772	141	0.044
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.044
positive regulation of cellular protein metabolic process	GO:0032270	89	0.043
protein targeting	GO:0006605	272	0.043
nucleotide metabolic process	GO:0009117	453	0.042
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.042
cortical actin cytoskeleton organization	GO:0030866	11	0.042
regulation of mitotic sister chromatid segregation	GO:0033047	30	0.042
mitotic spindle checkpoint	GO:0071174	34	0.041
positive regulation of gtp catabolic process	GO:0033126	80	0.041
ribonucleoprotein complex assembly	GO:0022618	143	0.040
vacuole organization	GO:0007033	75	0.040
negative regulation of chromatin silencing	GO:0031936	25	0.039
spindle assembly involved in mitosis	GO:0090307	4	0.039
positive regulation of gtpase activity	GO:0043547	80	0.039
protein acylation	GO:0043543	66	0.038
regulation of reproductive process	GO:2000241	24	0.038
response to organic cyclic compound	GO:0014070	1	0.038
response to osmotic stress	GO:0006970	83	0.037
single organism cellular localization	GO:1902580	375	0.037
regulation of signaling	GO:0023051	119	0.037	Fly
regulation of chromatin silencing at telomere	GO:0031938	27	0.036
positive regulation of cellular component organization	GO:0051130	116	0.036
dna repair	GO:0006281	236	0.035
fungal type cell wall organization or biogenesis	GO:0071852	169	0.035
response to starvation	GO:0042594	96	0.035
posttranscriptional regulation of gene expression	GO:0010608	115	0.035
positive regulation of nucleoside metabolic process	GO:0045979	97	0.034
cellular response to dna damage stimulus	GO:0006974	287	0.033
chromosome segregation	GO:0007059	159	0.033
positive regulation of purine nucleotide metabolic process	GO:1900544	100	0.033
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.033
rrna metabolic process	GO:0016072	244	0.032
internal peptidyl lysine acetylation	GO:0018393	52	0.032
methylation	GO:0032259	101	0.032
regulation of gene expression epigenetic	GO:0040029	147	0.032
response to inorganic substance	GO:0010035	47	0.032
positive regulation of cellular biosynthetic process	GO:0031328	336	0.031
ribose phosphate metabolic process	GO:0019693	384	0.031
invasive filamentous growth	GO:0036267	65	0.031
chromatin organization	GO:0006325	242	0.031
cell wall organization or biogenesis	GO:0071554	190	0.030
response to nutrient levels	GO:0031667	150	0.030
carboxylic acid metabolic process	GO:0019752	338	0.030
budding cell bud growth	GO:0007117	29	0.029
pyrimidine containing compound metabolic process	GO:0072527	37	0.029
positive regulation of organelle organization	GO:0010638	85	0.028
protein localization to organelle	GO:0033365	337	0.028
transposition	GO:0032196	20	0.028
regulation of protein serine threonine kinase activity	GO:0071900	41	0.028
maintenance of protein location	GO:0045185	53	0.028
fungal type cell wall organization	GO:0031505	145	0.028
exit from mitosis	GO:0010458	37	0.028
positive regulation of chromatin modification	GO:1903310	13	0.027
positive regulation of cellular component biogenesis	GO:0044089	45	0.027
protein alkylation	GO:0008213	48	0.027
negative regulation of protein processing	GO:0010955	33	0.027
regulation of cellular amine metabolic process	GO:0033238	21	0.027
dephosphorylation	GO:0016311	127	0.027
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	30	0.027
organic hydroxy compound transport	GO:0015850	41	0.026
cellular response to starvation	GO:0009267	90	0.026
positive regulation of protein metabolic process	GO:0051247	93	0.026
negative regulation of intracellular signal transduction	GO:1902532	27	0.025
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	36	0.025
regulation of cellular localization	GO:0060341	50	0.025
cellular developmental process	GO:0048869	191	0.025	Fly
regulation of transport	GO:0051049	85	0.025	Human
response to endogenous stimulus	GO:0009719	26	0.025
aging	GO:0007568	71	0.025
negative regulation of proteasomal protein catabolic process	GO:1901799	25	0.025
regulation of protein processing	GO:0070613	34	0.024
regulation of translation	GO:0006417	89	0.024
maintenance of protein location in cell	GO:0032507	50	0.024
response to oxidative stress	GO:0006979	99	0.024
histone deacetylation	GO:0016575	26	0.024
recombinational repair	GO:0000725	64	0.024
maintenance of cell polarity	GO:0030011	10	0.024
maintenance of location	GO:0051235	66	0.024
response to temperature stimulus	GO:0009266	74	0.023
cellular response to heat	GO:0034605	53	0.023
regulation of chromosome organization	GO:0033044	66	0.023
rrna processing	GO:0006364	227	0.023
replicative cell aging	GO:0001302	46	0.022
regulation of transcription by pheromones	GO:0009373	14	0.022
protein processing	GO:0016485	64	0.022
response to external stimulus	GO:0009605	158	0.022
regulation of hydrolase activity	GO:0051336	133	0.022
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.022
vacuole fusion	GO:0097576	40	0.021
regulation of conjugation	GO:0046999	16	0.021
negative regulation of cell cycle phase transition	GO:1901988	59	0.021
g1 s transition of mitotic cell cycle	GO:0000082	64	0.021
actin filament organization	GO:0007015	56	0.021	Fly
negative regulation of mitotic cell cycle	GO:0045930	63	0.021
positive regulation of gene expression epigenetic	GO:0045815	25	0.021
regulation of metal ion transport	GO:0010959	2	0.020	Human
programmed cell death	GO:0012501	30	0.020	Rat
cation homeostasis	GO:0055080	105	0.020	Rat
cell cycle phase transition	GO:0044770	144	0.020
reciprocal dna recombination	GO:0035825	54	0.020
regulation of growth	GO:0040008	50	0.020
positive regulation of apoptotic process	GO:0043065	3	0.019
negative regulation of signal transduction	GO:0009968	30	0.019
double strand break repair via homologous recombination	GO:0000724	54	0.019
negative regulation of proteolysis	GO:0045861	33	0.019
autophagy	GO:0006914	106	0.019
protein localization to nucleus	GO:0034504	74	0.019
septin ring organization	GO:0031106	26	0.019
nuclear transcribed mrna catabolic process deadenylation dependent decay	GO:0000288	44	0.019
regulation of cellular protein catabolic process	GO:1903362	36	0.019
protein dna complex subunit organization	GO:0071824	153	0.019
death	GO:0016265	30	0.018	Rat
positive regulation of programmed cell death	GO:0043068	3	0.018
cellular component disassembly	GO:0022411	86	0.018
ras protein signal transduction	GO:0007265	29	0.018
regulation of chromatin silencing	GO:0031935	39	0.018
generation of precursor metabolites and energy	GO:0006091	147	0.018
lipid metabolic process	GO:0006629	269	0.018
peptidyl lysine modification	GO:0018205	77	0.018
regulation of exit from mitosis	GO:0007096	29	0.018
stress activated mapk cascade	GO:0051403	4	0.017
chromosome separation	GO:0051304	33	0.017
cellular homeostasis	GO:0019725	138	0.017	Rat
protein maturation	GO:0051604	76	0.017
negative regulation of response to stimulus	GO:0048585	40	0.017
microtubule polymerization or depolymerization	GO:0031109	36	0.017
cellular response to nutrient levels	GO:0031669	144	0.017
peroxisome organization	GO:0007031	68	0.017
cellular metal ion homeostasis	GO:0006875	78	0.017	Rat
cellular response to extracellular stimulus	GO:0031668	150	0.016
response to organonitrogen compound	GO:0010243	18	0.016
regulation of cytoskeleton organization	GO:0051493	63	0.016
histone acetylation	GO:0016573	51	0.016
anatomical structure morphogenesis	GO:0009653	160	0.016	Fly
mitotic cytokinesis	GO:0000281	58	0.016
protein acetylation	GO:0006473	59	0.016
positive regulation of intracellular protein transport	GO:0090316	3	0.016
divalent metal ion transport	GO:0070838	17	0.016	Human Rat
cell death	GO:0008219	30	0.015	Rat
positive regulation of cell cycle	GO:0045787	32	0.015
cellular response to hypoxia	GO:0071456	4	0.015	Rat
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.015
negative regulation of phosphorus metabolic process	GO:0010563	49	0.015
positive regulation of signal transduction	GO:0009967	20	0.015
positive regulation of hydrolase activity	GO:0051345	112	0.015	Fly
negative regulation of cytoskeleton organization	GO:0051494	24	0.015
energy derivation by oxidation of organic compounds	GO:0015980	125	0.015
organelle assembly	GO:0070925	118	0.015
actin filament based process	GO:0030029	104	0.015	Fly
cell aging	GO:0007569	70	0.015
negative regulation of cellular protein catabolic process	GO:1903363	27	0.015
regulation of protein dephosphorylation	GO:0035304	4	0.015
negative regulation of gene silencing	GO:0060969	27	0.014
negative regulation of phosphate metabolic process	GO:0045936	49	0.014
cytoskeleton dependent cytokinesis	GO:0061640	65	0.014
chemical homeostasis	GO:0048878	137	0.014	Rat
protein ubiquitination	GO:0016567	118	0.014
negative regulation of mitotic sister chromatid segregation	GO:0033048	24	0.014
negative regulation of phosphorylation	GO:0042326	28	0.014
regulation of cellular response to stress	GO:0080135	50	0.014
microtubule based movement	GO:0007018	18	0.014
positive regulation of cell death	GO:0010942	3	0.014
positive regulation of histone modification	GO:0031058	12	0.014
protein dna complex assembly	GO:0065004	105	0.014
dna replication initiation	GO:0006270	48	0.013
sister chromatid segregation	GO:0000819	93	0.013
regulation of actin filament based process	GO:0032970	31	0.013
sterol transport	GO:0015918	24	0.013
protein folding	GO:0006457	94	0.013
dna damage checkpoint	GO:0000077	29	0.013
protein localization to membrane	GO:0072657	102	0.013
mitotic spindle elongation	GO:0000022	14	0.013
protein localization to endoplasmic reticulum	GO:0070972	47	0.013
cellular chemical homeostasis	GO:0055082	123	0.013	Rat
vesicle organization	GO:0016050	68	0.013
macromolecular complex disassembly	GO:0032984	80	0.013
internal protein amino acid acetylation	GO:0006475	52	0.012
mitotic spindle assembly checkpoint	GO:0007094	23	0.012
negative regulation of mapk cascade	GO:0043409	11	0.012
cytokinesis	GO:0000910	92	0.012
macroautophagy	GO:0016236	55	0.012
regulation of response to external stimulus	GO:0032101	20	0.012	Fly
ncrna catabolic process	GO:0034661	33	0.012
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.012
transposition rna mediated	GO:0032197	17	0.012
rho protein signal transduction	GO:0007266	12	0.012
regulation of cellular component biogenesis	GO:0044087	112	0.012
response to heat	GO:0009408	69	0.012
establishment of protein localization to membrane	GO:0090150	99	0.011
cell cycle dna replication	GO:0044786	36	0.011
regulation of protein localization	GO:0032880	62	0.011
cellular response to oxidative stress	GO:0034599	94	0.011
protein complex localization	GO:0031503	32	0.011
regulation of dna replication	GO:0006275	51	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	7	0.011
lipid localization	GO:0010876	60	0.011
regulation of dna metabolic process	GO:0051052	100	0.011
organelle disassembly	GO:1903008	13	0.011
protein dephosphorylation	GO:0006470	40	0.011
peptidyl lysine acetylation	GO:0018394	52	0.011
regulation of macroautophagy	GO:0016241	15	0.011
regulation of cellular amino acid metabolic process	GO:0006521	16	0.011
lipid transport	GO:0006869	58	0.011
positive regulation of catalytic activity	GO:0043085	178	0.011	Fly
nuclear rna surveillance	GO:0071027	30	0.010
spindle assembly	GO:0051225	9	0.010
negative regulation of meiosis	GO:0045835	23	0.010
cell growth	GO:0016049	89	0.010
developmental process involved in reproduction	GO:0003006	159	0.010
regulation of multi organism process	GO:0043900	20	0.010

STE4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.047	Human

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