IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

57 known processes

CRN1 (YLR429W)

Crn1p

SGD: S000004421
Entrez: 851148
UniProtKB: Q06440

Process Predictions
Disease Predictions

CRN1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cytoskeleton organization	GO:0007010	230	0.993
actin cytoskeleton organization	GO:0030036	100	0.669
cell division	GO:0051301	205	0.582
organic acid metabolic process	GO:0006082	352	0.507
regulation of nuclear division	GO:0051783	103	0.499
vesicle mediated transport	GO:0016192	335	0.423	Human Mouse
developmental process	GO:0032502	261	0.385	Human Mouse Worm Fly
chromosome segregation	GO:0007059	159	0.349
establishment of protein localization	GO:0045184	367	0.318
negative regulation of macromolecule metabolic process	GO:0010605	375	0.278
single organism catabolic process	GO:0044712	619	0.269
single organism cellular localization	GO:1902580	375	0.267	Fly
organelle localization	GO:0051640	128	0.254
single organism reproductive process	GO:0044702	159	0.251	Worm
regulation of mitosis	GO:0007088	65	0.246
microtubule based process	GO:0007017	117	0.244
protein complex assembly	GO:0006461	302	0.236	Human Mouse
actin filament based process	GO:0030029	104	0.228
mitotic cell cycle	GO:0000278	306	0.224
nucleoside catabolic process	GO:0009164	335	0.224
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.217
regulation of cell division	GO:0051302	113	0.211
cellular nitrogen compound catabolic process	GO:0044270	494	0.211
endomembrane system organization	GO:0010256	74	0.206
ncrna processing	GO:0034470	330	0.204
regulation of catalytic activity	GO:0050790	307	0.189
cellular protein complex disassembly	GO:0043624	42	0.179
organic cyclic compound catabolic process	GO:1901361	499	0.178
negative regulation of cell cycle process	GO:0010948	86	0.175
cellular developmental process	GO:0048869	191	0.174	Human Mouse Worm Fly
positive regulation of catalytic activity	GO:0043085	178	0.173
regulation of cellular catabolic process	GO:0031329	195	0.171
reproductive process	GO:0022414	248	0.171	Worm
nucleobase containing compound catabolic process	GO:0034655	479	0.165
sexual reproduction	GO:0019953	216	0.163	Worm
mitotic cell cycle process	GO:1903047	294	0.156
golgi vesicle transport	GO:0048193	188	0.153	Human
nucleic acid phosphodiester bond hydrolysis	GO:0090305	194	0.152
negative regulation of cellular component organization	GO:0051129	109	0.149
organonitrogen compound biosynthetic process	GO:1901566	314	0.140
establishment of protein localization to organelle	GO:0072594	278	0.139
macromolecule catabolic process	GO:0009057	383	0.136
mitotic nuclear division	GO:0007067	131	0.130
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.130
positive regulation of hydrolase activity	GO:0051345	112	0.129
meiotic nuclear division	GO:0007126	163	0.128	Worm
protein localization to organelle	GO:0033365	337	0.128
developmental process involved in reproduction	GO:0003006	159	0.127	Worm
regulation of molecular function	GO:0065009	320	0.124
negative regulation of cellular catabolic process	GO:0031330	43	0.124
multi organism reproductive process	GO:0044703	216	0.123	Worm
establishment of protein localization to membrane	GO:0090150	99	0.121
purine containing compound catabolic process	GO:0072523	332	0.121
microtubule cytoskeleton organization	GO:0000226	109	0.120
dna repair	GO:0006281	236	0.119
single organism developmental process	GO:0044767	258	0.118	Human Mouse Worm Fly
nuclear division	GO:0000280	263	0.111	Worm
regulation of catabolic process	GO:0009894	199	0.109
reproduction of a single celled organism	GO:0032505	191	0.108
organophosphate metabolic process	GO:0019637	597	0.104
protein transport	GO:0015031	345	0.099
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.098
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	137	0.097
protein targeting	GO:0006605	272	0.095
aromatic compound catabolic process	GO:0019439	491	0.094
negative regulation of cell cycle	GO:0045786	91	0.093
negative regulation of biosynthetic process	GO:0009890	312	0.092
protein complex biogenesis	GO:0070271	314	0.092	Human Mouse
regulation of organelle organization	GO:0033043	243	0.090
cellular macromolecule catabolic process	GO:0044265	363	0.089
glycosyl compound catabolic process	GO:1901658	335	0.088
regulation of protein complex assembly	GO:0043254	77	0.085
anatomical structure development	GO:0048856	160	0.083	Human Mouse Worm Fly
nuclear transport	GO:0051169	165	0.080
regulation of cell cycle process	GO:0010564	150	0.079
regulation of protein metabolic process	GO:0051246	237	0.076
regulation of cellular component organization	GO:0051128	334	0.075
negative regulation of organelle organization	GO:0010639	103	0.075
cell communication	GO:0007154	345	0.075	Mouse
positive regulation of molecular function	GO:0044093	185	0.073
protein catabolic process	GO:0030163	221	0.073
organelle fission	GO:0048285	272	0.073	Worm
regulation of cell cycle	GO:0051726	195	0.072
heterocycle catabolic process	GO:0046700	494	0.072
nuclear export	GO:0051168	124	0.068
ribonucleotide catabolic process	GO:0009261	327	0.066
actin filament organization	GO:0007015	56	0.064
positive regulation of cellular protein metabolic process	GO:0032270	89	0.064
organophosphate catabolic process	GO:0046434	338	0.063
mitochondrion organization	GO:0007005	261	0.062
er to golgi vesicle mediated transport	GO:0006888	86	0.062
ribonucleoside metabolic process	GO:0009119	389	0.061
regulation of mitotic cell cycle	GO:0007346	107	0.060
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.060
purine ribonucleoside catabolic process	GO:0046130	330	0.059
regulation of biological quality	GO:0065008	391	0.059
multi organism cellular process	GO:0044764	120	0.055
growth	GO:0040007	157	0.055
endocytosis	GO:0006897	90	0.055	Human
modification dependent macromolecule catabolic process	GO:0043632	203	0.055
meiotic cell cycle	GO:0051321	272	0.054	Worm
negative regulation of cellular biosynthetic process	GO:0031327	312	0.054
gene silencing	GO:0016458	151	0.053
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.053
protein polymerization	GO:0051258	51	0.053	Human Mouse
single organism membrane organization	GO:0044802	275	0.052	Mouse Fly
reproductive process in single celled organism	GO:0022413	145	0.051
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.050
negative regulation of catabolic process	GO:0009895	43	0.050
rrna processing	GO:0006364	227	0.050
proteasomal protein catabolic process	GO:0010498	141	0.050
nucleotide metabolic process	GO:0009117	453	0.049
regulation of chromosome organization	GO:0033044	66	0.049
mrna metabolic process	GO:0016071	269	0.048
nucleobase containing small molecule metabolic process	GO:0055086	491	0.046
regulation of cellular protein metabolic process	GO:0032268	232	0.045
regulation of hydrolase activity	GO:0051336	133	0.045
carbohydrate derivative catabolic process	GO:1901136	339	0.044
purine containing compound metabolic process	GO:0072521	400	0.043
peptidyl amino acid modification	GO:0018193	116	0.043
establishment of organelle localization	GO:0051656	96	0.043
multi organism process	GO:0051704	233	0.043	Worm Fly
glycerolipid metabolic process	GO:0046486	108	0.043
cellular component morphogenesis	GO:0032989	97	0.042	Human Mouse Fly
positive regulation of protein metabolic process	GO:0051247	93	0.041
sexual sporulation	GO:0034293	113	0.041
response to chemical	GO:0042221	390	0.041	Human Mouse Fly
nucleobase containing compound transport	GO:0015931	124	0.040
mrna catabolic process	GO:0006402	93	0.040
double strand break repair	GO:0006302	105	0.039
dna packaging	GO:0006323	55	0.038
meiotic cell cycle process	GO:1903046	229	0.038
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.037
proteolysis	GO:0006508	268	0.037
cell differentiation	GO:0030154	161	0.036	Worm Fly
protein localization to membrane	GO:0072657	102	0.036	Fly
regulation of meiotic cell cycle	GO:0051445	43	0.036
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.035
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.034
cellular protein complex assembly	GO:0043623	209	0.034	Human Mouse
negative regulation of rna biosynthetic process	GO:1902679	260	0.034
negative regulation of gene expression	GO:0010629	312	0.034
negative regulation of nuclear division	GO:0051784	62	0.034
negative regulation of mitotic cell cycle	GO:0045930	63	0.033
cell morphogenesis	GO:0000902	30	0.032	Human Mouse Fly
mitotic cell cycle checkpoint	GO:0007093	56	0.032
dna dependent dna replication	GO:0006261	115	0.031
carbohydrate derivative metabolic process	GO:1901135	549	0.031
dna conformation change	GO:0071103	98	0.031
negative regulation of chromosome organization	GO:2001251	39	0.031
protein folding	GO:0006457	94	0.031
positive regulation of gene expression	GO:0010628	321	0.030
regulation of gene expression epigenetic	GO:0040029	147	0.030
regulation of reproductive process	GO:2000241	24	0.030
glycosyl compound metabolic process	GO:1901657	398	0.030
purine nucleoside catabolic process	GO:0006152	330	0.030
mitochondrial translation	GO:0032543	52	0.029
conjugation with cellular fusion	GO:0000747	106	0.029
copii coated vesicle budding	GO:0090114	12	0.029
purine ribonucleotide catabolic process	GO:0009154	327	0.029
rna localization	GO:0006403	112	0.028
organic anion transport	GO:0015711	114	0.027
regulation of cell cycle phase transition	GO:1901987	70	0.026
cell aging	GO:0007569	70	0.026
establishment or maintenance of cell polarity	GO:0007163	96	0.026
meiosis i	GO:0007127	92	0.026
negative regulation of cellular metabolic process	GO:0031324	407	0.026
regulation of cell communication	GO:0010646	124	0.026
protein localization to plasma membrane	GO:0072659	18	0.025
alcohol metabolic process	GO:0006066	112	0.025
translation	GO:0006412	230	0.025
cellular amine metabolic process	GO:0044106	51	0.025
regulation of meiosis	GO:0040020	42	0.024
protein depolymerization	GO:0051261	21	0.024
gtp metabolic process	GO:0046039	107	0.024
regulation of cellular component biogenesis	GO:0044087	112	0.024
negative regulation of rna metabolic process	GO:0051253	262	0.023
chromatin silencing	GO:0006342	147	0.023
chromatin organization	GO:0006325	242	0.023
plasma membrane organization	GO:0007009	21	0.023
response to organic cyclic compound	GO:0014070	1	0.023
phospholipid metabolic process	GO:0006644	125	0.023
posttranscriptional regulation of gene expression	GO:0010608	115	0.023
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.023
positive regulation of rna metabolic process	GO:0051254	294	0.023
organonitrogen compound catabolic process	GO:1901565	404	0.022
nucleoside phosphate catabolic process	GO:1901292	331	0.022
cellular component disassembly	GO:0022411	86	0.022
er associated ubiquitin dependent protein catabolic process	GO:0030433	46	0.022
regulation of developmental process	GO:0050793	30	0.022	Human Mouse
purine nucleotide catabolic process	GO:0006195	328	0.022
positive regulation of macromolecule metabolic process	GO:0010604	394	0.022
guanosine containing compound metabolic process	GO:1901068	111	0.022
trna processing	GO:0008033	101	0.022
glycerolipid biosynthetic process	GO:0045017	71	0.021
membrane organization	GO:0061024	276	0.021	Mouse Fly
actin filament bundle organization	GO:0061572	19	0.021	Human
positive regulation of translation	GO:0045727	34	0.021
metal ion homeostasis	GO:0055065	79	0.021	Mouse
rna catabolic process	GO:0006401	118	0.021
ribonucleoside catabolic process	GO:0042454	332	0.021
rrna metabolic process	GO:0016072	244	0.020
positive regulation of protein polymerization	GO:0032273	22	0.020
actin filament bundle assembly	GO:0051017	19	0.020	Human
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.019
cellular protein catabolic process	GO:0044257	213	0.019
gene conversion	GO:0035822	14	0.019
alcohol biosynthetic process	GO:0046165	75	0.019
protein acylation	GO:0043543	66	0.019
chromosome localization	GO:0050000	20	0.019
dna recombination	GO:0006310	172	0.018
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.018
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.018
response to extracellular stimulus	GO:0009991	156	0.018
nucleic acid transport	GO:0050657	94	0.018
protein localization to vacuole	GO:0072665	92	0.018
homeostatic process	GO:0042592	227	0.018	Mouse
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.018
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.017
meiotic chromosome segregation	GO:0045132	31	0.017
regulation of protein modification process	GO:0031399	110	0.017
maintenance of location	GO:0051235	66	0.017
purine ribonucleotide metabolic process	GO:0009150	372	0.017
negative regulation of transcription dna templated	GO:0045892	258	0.017
regulation of signaling	GO:0023051	119	0.016
regulation of actin filament polymerization	GO:0030833	19	0.016
regulation of proteasomal protein catabolic process	GO:0061136	34	0.016
nucleoside triphosphate catabolic process	GO:0009143	329	0.016
phosphatidylcholine biosynthetic process	GO:0006656	18	0.016
positive regulation of cellular catabolic process	GO:0031331	128	0.016
nucleoside phosphate metabolic process	GO:0006753	458	0.016
mitotic spindle checkpoint	GO:0071174	34	0.015
nucleus organization	GO:0006997	62	0.015
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.015
positive regulation of protein modification process	GO:0031401	49	0.015
regulation of signal transduction	GO:0009966	114	0.015
purine ribonucleoside metabolic process	GO:0046128	380	0.015
purine nucleotide metabolic process	GO:0006163	376	0.015
positive regulation of apoptotic process	GO:0043065	3	0.015
negative regulation of cellular protein catabolic process	GO:1903363	27	0.014
response to organic substance	GO:0010033	182	0.014	Mouse
regulation of nucleotide catabolic process	GO:0030811	106	0.014
internal protein amino acid acetylation	GO:0006475	52	0.014
regulation of transferase activity	GO:0051338	83	0.014
protein complex disassembly	GO:0043241	70	0.014
reciprocal dna recombination	GO:0035825	54	0.014
negative regulation of protein metabolic process	GO:0051248	85	0.014
amine metabolic process	GO:0009308	51	0.014
conjugation	GO:0000746	107	0.014
negative regulation of gene expression epigenetic	GO:0045814	147	0.014
gene conversion at mating type locus	GO:0007534	11	0.014
anatomical structure morphogenesis	GO:0009653	160	0.014	Human Mouse Fly
negative regulation of phosphate metabolic process	GO:0045936	49	0.014
cellular response to organic substance	GO:0071310	159	0.014	Mouse
purine nucleoside monophosphate catabolic process	GO:0009128	224	0.014
protein localization to nucleus	GO:0034504	74	0.014
anion transport	GO:0006820	145	0.013
trna wobble base modification	GO:0002097	27	0.013
dna dependent dna replication maintenance of fidelity	GO:0045005	14	0.013
cell cycle g2 m phase transition	GO:0044839	39	0.013
phosphatidylcholine metabolic process	GO:0046470	20	0.013
regulation of response to stimulus	GO:0048583	157	0.013
mitotic recombination	GO:0006312	55	0.013
regulation of gene silencing	GO:0060968	41	0.013
negative regulation of phosphorus metabolic process	GO:0010563	49	0.013
cell cycle phase transition	GO:0044770	144	0.013
modification dependent protein catabolic process	GO:0019941	181	0.012
regulation of purine nucleotide metabolic process	GO:1900542	109	0.012
positive regulation of organelle organization	GO:0010638	85	0.012
rna phosphodiester bond hydrolysis	GO:0090501	112	0.012
vesicle localization	GO:0051648	9	0.012
sister chromatid segregation	GO:0000819	93	0.012
g2 m transition of mitotic cell cycle	GO:0000086	38	0.012
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.012
regulation of translation	GO:0006417	89	0.012
intracellular protein transmembrane import	GO:0044743	67	0.012
pyridine containing compound metabolic process	GO:0072524	53	0.012
phosphatidylinositol metabolic process	GO:0046488	62	0.012
trna modification	GO:0006400	75	0.012
spindle assembly checkpoint	GO:0071173	23	0.012
regulation of nucleotide metabolic process	GO:0006140	110	0.012
dna replication	GO:0006260	147	0.012
negative regulation of mitosis	GO:0045839	39	0.012
poly a mrna export from nucleus	GO:0016973	24	0.012
carboxylic acid biosynthetic process	GO:0046394	152	0.012
steroid biosynthetic process	GO:0006694	35	0.012
cellular amino acid metabolic process	GO:0006520	225	0.012
ascospore formation	GO:0030437	107	0.011
spindle checkpoint	GO:0031577	35	0.011
sporulation	GO:0043934	132	0.011
regulation of dna dependent dna replication	GO:0090329	37	0.011
dna catabolic process	GO:0006308	42	0.011
trna wobble uridine modification	GO:0002098	26	0.011
cell wall organization	GO:0071555	146	0.011
cell cycle checkpoint	GO:0000075	82	0.011
protein dna complex subunit organization	GO:0071824	153	0.010
cellular lipid metabolic process	GO:0044255	229	0.010
mitochondrion localization	GO:0051646	29	0.010
guanosine containing compound catabolic process	GO:1901069	109	0.010
regulation of purine nucleotide catabolic process	GO:0033121	106	0.010
nucleoside metabolic process	GO:0009116	394	0.010
cellular biogenic amine metabolic process	GO:0006576	37	0.010
negative regulation of cytoskeleton organization	GO:0051494	24	0.010
iron sulfur cluster assembly	GO:0016226	22	0.010
regulation of nucleoside metabolic process	GO:0009118	106	0.010

CRN1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.096
	nervous system disease	DOID:863	0	0.012

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