| cytoskeleton organization | GO:0007010 | 230 | 0.993 | |
| actin cytoskeleton organization | GO:0030036 | 100 | 0.669 | |
| cell division | GO:0051301 | 205 | 0.582 | |
| organic acid metabolic process | GO:0006082 | 352 | 0.507 | |
| regulation of nuclear division | GO:0051783 | 103 | 0.499 | |
| vesicle mediated transport | GO:0016192 | 335 | 0.423 | Human Mouse |
| developmental process | GO:0032502 | 261 | 0.385 | Human Mouse Worm Fly |
| chromosome segregation | GO:0007059 | 159 | 0.349 | |
| establishment of protein localization | GO:0045184 | 367 | 0.318 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 375 | 0.278 | |
| single organism catabolic process | GO:0044712 | 619 | 0.269 | |
| single organism cellular localization | GO:1902580 | 375 | 0.267 | Fly |
| organelle localization | GO:0051640 | 128 | 0.254 | |
| single organism reproductive process | GO:0044702 | 159 | 0.251 | Worm |
| regulation of mitosis | GO:0007088 | 65 | 0.246 | |
| microtubule based process | GO:0007017 | 117 | 0.244 | |
| protein complex assembly | GO:0006461 | 302 | 0.236 | Human Mouse |
| actin filament based process | GO:0030029 | 104 | 0.228 | |
| mitotic cell cycle | GO:0000278 | 306 | 0.224 | |
| nucleoside catabolic process | GO:0009164 | 335 | 0.224 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 295 | 0.217 | |
| regulation of cell division | GO:0051302 | 113 | 0.211 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 494 | 0.211 | |
| endomembrane system organization | GO:0010256 | 74 | 0.206 | |
| ncrna processing | GO:0034470 | 330 | 0.204 | |
| regulation of catalytic activity | GO:0050790 | 307 | 0.189 | |
| cellular protein complex disassembly | GO:0043624 | 42 | 0.179 | |
| organic cyclic compound catabolic process | GO:1901361 | 499 | 0.178 | |
| negative regulation of cell cycle process | GO:0010948 | 86 | 0.175 | |
| cellular developmental process | GO:0048869 | 191 | 0.174 | Human Mouse Worm Fly |
| positive regulation of catalytic activity | GO:0043085 | 178 | 0.173 | |
| regulation of cellular catabolic process | GO:0031329 | 195 | 0.171 | |
| reproductive process | GO:0022414 | 248 | 0.171 | Worm |
| nucleobase containing compound catabolic process | GO:0034655 | 479 | 0.165 | |
| sexual reproduction | GO:0019953 | 216 | 0.163 | Worm |
| mitotic cell cycle process | GO:1903047 | 294 | 0.156 | |
| golgi vesicle transport | GO:0048193 | 188 | 0.153 | Human |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 194 | 0.152 | |
| negative regulation of cellular component organization | GO:0051129 | 109 | 0.149 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 314 | 0.140 | |
| establishment of protein localization to organelle | GO:0072594 | 278 | 0.139 | |
| macromolecule catabolic process | GO:0009057 | 383 | 0.136 | |
| mitotic nuclear division | GO:0007067 | 131 | 0.130 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 198 | 0.130 | |
| positive regulation of hydrolase activity | GO:0051345 | 112 | 0.129 | |
| meiotic nuclear division | GO:0007126 | 163 | 0.128 | Worm |
| protein localization to organelle | GO:0033365 | 337 | 0.128 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.127 | Worm |
| regulation of molecular function | GO:0065009 | 320 | 0.124 | |
| negative regulation of cellular catabolic process | GO:0031330 | 43 | 0.124 | |
| multi organism reproductive process | GO:0044703 | 216 | 0.123 | Worm |
| establishment of protein localization to membrane | GO:0090150 | 99 | 0.121 | |
| purine containing compound catabolic process | GO:0072523 | 332 | 0.121 | |
| microtubule cytoskeleton organization | GO:0000226 | 109 | 0.120 | |
| dna repair | GO:0006281 | 236 | 0.119 | |
| single organism developmental process | GO:0044767 | 258 | 0.118 | Human Mouse Worm Fly |
| nuclear division | GO:0000280 | 263 | 0.111 | Worm |
| regulation of catabolic process | GO:0009894 | 199 | 0.109 | |
| reproduction of a single celled organism | GO:0032505 | 191 | 0.108 | |
| organophosphate metabolic process | GO:0019637 | 597 | 0.104 | |
| protein transport | GO:0015031 | 345 | 0.099 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 260 | 0.098 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 137 | 0.097 | |
| protein targeting | GO:0006605 | 272 | 0.095 | |
| aromatic compound catabolic process | GO:0019439 | 491 | 0.094 | |
| negative regulation of cell cycle | GO:0045786 | 91 | 0.093 | |
| negative regulation of biosynthetic process | GO:0009890 | 312 | 0.092 | |
| protein complex biogenesis | GO:0070271 | 314 | 0.092 | Human Mouse |
| regulation of organelle organization | GO:0033043 | 243 | 0.090 | |
| cellular macromolecule catabolic process | GO:0044265 | 363 | 0.089 | |
| glycosyl compound catabolic process | GO:1901658 | 335 | 0.088 | |
| regulation of protein complex assembly | GO:0043254 | 77 | 0.085 | |
| anatomical structure development | GO:0048856 | 160 | 0.083 | Human Mouse Worm Fly |
| nuclear transport | GO:0051169 | 165 | 0.080 | |
| regulation of cell cycle process | GO:0010564 | 150 | 0.079 | |
| regulation of protein metabolic process | GO:0051246 | 237 | 0.076 | |
| regulation of cellular component organization | GO:0051128 | 334 | 0.075 | |
| negative regulation of organelle organization | GO:0010639 | 103 | 0.075 | |
| cell communication | GO:0007154 | 345 | 0.075 | Mouse |
| positive regulation of molecular function | GO:0044093 | 185 | 0.073 | |
| protein catabolic process | GO:0030163 | 221 | 0.073 | |
| organelle fission | GO:0048285 | 272 | 0.073 | Worm |
| regulation of cell cycle | GO:0051726 | 195 | 0.072 | |
| heterocycle catabolic process | GO:0046700 | 494 | 0.072 | |
| nuclear export | GO:0051168 | 124 | 0.068 | |
| ribonucleotide catabolic process | GO:0009261 | 327 | 0.066 | |
| actin filament organization | GO:0007015 | 56 | 0.064 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 89 | 0.064 | |
| organophosphate catabolic process | GO:0046434 | 338 | 0.063 | |
| mitochondrion organization | GO:0007005 | 261 | 0.062 | |
| er to golgi vesicle mediated transport | GO:0006888 | 86 | 0.062 | |
| ribonucleoside metabolic process | GO:0009119 | 389 | 0.061 | |
| regulation of mitotic cell cycle | GO:0007346 | 107 | 0.060 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 327 | 0.060 | |
| purine ribonucleoside catabolic process | GO:0046130 | 330 | 0.059 | |
| regulation of biological quality | GO:0065008 | 391 | 0.059 | |
| multi organism cellular process | GO:0044764 | 120 | 0.055 | |
| growth | GO:0040007 | 157 | 0.055 | |
| endocytosis | GO:0006897 | 90 | 0.055 | Human |
| modification dependent macromolecule catabolic process | GO:0043632 | 203 | 0.055 | |
| meiotic cell cycle | GO:0051321 | 272 | 0.054 | Worm |
| negative regulation of cellular biosynthetic process | GO:0031327 | 312 | 0.054 | |
| gene silencing | GO:0016458 | 151 | 0.053 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 409 | 0.053 | |
| protein polymerization | GO:0051258 | 51 | 0.053 | Human Mouse |
| single organism membrane organization | GO:0044802 | 275 | 0.052 | Mouse Fly |
| reproductive process in single celled organism | GO:0022413 | 145 | 0.051 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 300 | 0.050 | |
| negative regulation of catabolic process | GO:0009895 | 43 | 0.050 | |
| rrna processing | GO:0006364 | 227 | 0.050 | |
| proteasomal protein catabolic process | GO:0010498 | 141 | 0.050 | |
| nucleotide metabolic process | GO:0009117 | 453 | 0.049 | |
| regulation of chromosome organization | GO:0033044 | 66 | 0.049 | |
| mrna metabolic process | GO:0016071 | 269 | 0.048 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 491 | 0.046 | |
| regulation of cellular protein metabolic process | GO:0032268 | 232 | 0.045 | |
| regulation of hydrolase activity | GO:0051336 | 133 | 0.045 | |
| carbohydrate derivative catabolic process | GO:1901136 | 339 | 0.044 | |
| purine containing compound metabolic process | GO:0072521 | 400 | 0.043 | |
| peptidyl amino acid modification | GO:0018193 | 116 | 0.043 | |
| establishment of organelle localization | GO:0051656 | 96 | 0.043 | |
| multi organism process | GO:0051704 | 233 | 0.043 | Worm Fly |
| glycerolipid metabolic process | GO:0046486 | 108 | 0.043 | |
| cellular component morphogenesis | GO:0032989 | 97 | 0.042 | Human Mouse Fly |
| positive regulation of protein metabolic process | GO:0051247 | 93 | 0.041 | |
| sexual sporulation | GO:0034293 | 113 | 0.041 | |
| response to chemical | GO:0042221 | 390 | 0.041 | Human Mouse Fly |
| nucleobase containing compound transport | GO:0015931 | 124 | 0.040 | |
| mrna catabolic process | GO:0006402 | 93 | 0.040 | |
| double strand break repair | GO:0006302 | 105 | 0.039 | |
| dna packaging | GO:0006323 | 55 | 0.038 | |
| meiotic cell cycle process | GO:1903046 | 229 | 0.038 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 68 | 0.037 | |
| proteolysis | GO:0006508 | 268 | 0.037 | |
| cell differentiation | GO:0030154 | 161 | 0.036 | Worm Fly |
| protein localization to membrane | GO:0072657 | 102 | 0.036 | Fly |
| regulation of meiotic cell cycle | GO:0051445 | 43 | 0.036 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 136 | 0.035 | |
| sexual sporulation resulting in formation of a cellular spore | GO:0043935 | 113 | 0.034 | |
| cellular protein complex assembly | GO:0043623 | 209 | 0.034 | Human Mouse |
| negative regulation of rna biosynthetic process | GO:1902679 | 260 | 0.034 | |
| negative regulation of gene expression | GO:0010629 | 312 | 0.034 | |
| negative regulation of nuclear division | GO:0051784 | 62 | 0.034 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 63 | 0.033 | |
| cell morphogenesis | GO:0000902 | 30 | 0.032 | Human Mouse Fly |
| mitotic cell cycle checkpoint | GO:0007093 | 56 | 0.032 | |
| dna dependent dna replication | GO:0006261 | 115 | 0.031 | |
| carbohydrate derivative metabolic process | GO:1901135 | 549 | 0.031 | |
| dna conformation change | GO:0071103 | 98 | 0.031 | |
| negative regulation of chromosome organization | GO:2001251 | 39 | 0.031 | |
| protein folding | GO:0006457 | 94 | 0.031 | |
| positive regulation of gene expression | GO:0010628 | 321 | 0.030 | |
| regulation of gene expression epigenetic | GO:0040029 | 147 | 0.030 | |
| regulation of reproductive process | GO:2000241 | 24 | 0.030 | |
| glycosyl compound metabolic process | GO:1901657 | 398 | 0.030 | |
| purine nucleoside catabolic process | GO:0006152 | 330 | 0.030 | |
| mitochondrial translation | GO:0032543 | 52 | 0.029 | |
| conjugation with cellular fusion | GO:0000747 | 106 | 0.029 | |
| copii coated vesicle budding | GO:0090114 | 12 | 0.029 | |
| purine ribonucleotide catabolic process | GO:0009154 | 327 | 0.029 | |
| rna localization | GO:0006403 | 112 | 0.028 | |
| organic anion transport | GO:0015711 | 114 | 0.027 | |
| regulation of cell cycle phase transition | GO:1901987 | 70 | 0.026 | |
| cell aging | GO:0007569 | 70 | 0.026 | |
| establishment or maintenance of cell polarity | GO:0007163 | 96 | 0.026 | |
| meiosis i | GO:0007127 | 92 | 0.026 | |
| negative regulation of cellular metabolic process | GO:0031324 | 407 | 0.026 | |
| regulation of cell communication | GO:0010646 | 124 | 0.026 | |
| protein localization to plasma membrane | GO:0072659 | 18 | 0.025 | |
| alcohol metabolic process | GO:0006066 | 112 | 0.025 | |
| translation | GO:0006412 | 230 | 0.025 | |
| cellular amine metabolic process | GO:0044106 | 51 | 0.025 | |
| regulation of meiosis | GO:0040020 | 42 | 0.024 | |
| protein depolymerization | GO:0051261 | 21 | 0.024 | |
| gtp metabolic process | GO:0046039 | 107 | 0.024 | |
| regulation of cellular component biogenesis | GO:0044087 | 112 | 0.024 | |
| negative regulation of rna metabolic process | GO:0051253 | 262 | 0.023 | |
| chromatin silencing | GO:0006342 | 147 | 0.023 | |
| chromatin organization | GO:0006325 | 242 | 0.023 | |
| plasma membrane organization | GO:0007009 | 21 | 0.023 | |
| response to organic cyclic compound | GO:0014070 | 1 | 0.023 | |
| phospholipid metabolic process | GO:0006644 | 125 | 0.023 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 115 | 0.023 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 327 | 0.023 | |
| positive regulation of rna metabolic process | GO:0051254 | 294 | 0.023 | |
| organonitrogen compound catabolic process | GO:1901565 | 404 | 0.022 | |
| nucleoside phosphate catabolic process | GO:1901292 | 331 | 0.022 | |
| cellular component disassembly | GO:0022411 | 86 | 0.022 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 46 | 0.022 | |
| regulation of developmental process | GO:0050793 | 30 | 0.022 | Human Mouse |
| purine nucleotide catabolic process | GO:0006195 | 328 | 0.022 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 394 | 0.022 | |
| guanosine containing compound metabolic process | GO:1901068 | 111 | 0.022 | |
| trna processing | GO:0008033 | 101 | 0.022 | |
| glycerolipid biosynthetic process | GO:0045017 | 71 | 0.021 | |
| membrane organization | GO:0061024 | 276 | 0.021 | Mouse Fly |
| actin filament bundle organization | GO:0061572 | 19 | 0.021 | Human |
| positive regulation of translation | GO:0045727 | 34 | 0.021 | |
| metal ion homeostasis | GO:0055065 | 79 | 0.021 | Mouse |
| rna catabolic process | GO:0006401 | 118 | 0.021 | |
| ribonucleoside catabolic process | GO:0042454 | 332 | 0.021 | |
| rrna metabolic process | GO:0016072 | 244 | 0.020 | |
| positive regulation of protein polymerization | GO:0032273 | 22 | 0.020 | |
| actin filament bundle assembly | GO:0051017 | 19 | 0.020 | Human |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 291 | 0.019 | |
| cellular protein catabolic process | GO:0044257 | 213 | 0.019 | |
| gene conversion | GO:0035822 | 14 | 0.019 | |
| alcohol biosynthetic process | GO:0046165 | 75 | 0.019 | |
| protein acylation | GO:0043543 | 66 | 0.019 | |
| chromosome localization | GO:0050000 | 20 | 0.019 | |
| dna recombination | GO:0006310 | 172 | 0.018 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 329 | 0.018 | |
| sporulation resulting in formation of a cellular spore | GO:0030435 | 129 | 0.018 | |
| response to extracellular stimulus | GO:0009991 | 156 | 0.018 | |
| nucleic acid transport | GO:0050657 | 94 | 0.018 | |
| protein localization to vacuole | GO:0072665 | 92 | 0.018 | |
| homeostatic process | GO:0042592 | 227 | 0.018 | Mouse |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 354 | 0.018 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 57 | 0.017 | |
| meiotic chromosome segregation | GO:0045132 | 31 | 0.017 | |
| regulation of protein modification process | GO:0031399 | 110 | 0.017 | |
| maintenance of location | GO:0051235 | 66 | 0.017 | |
| purine ribonucleotide metabolic process | GO:0009150 | 372 | 0.017 | |
| negative regulation of transcription dna templated | GO:0045892 | 258 | 0.017 | |
| regulation of signaling | GO:0023051 | 119 | 0.016 | |
| regulation of actin filament polymerization | GO:0030833 | 19 | 0.016 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 34 | 0.016 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 329 | 0.016 | |
| phosphatidylcholine biosynthetic process | GO:0006656 | 18 | 0.016 | |
| positive regulation of cellular catabolic process | GO:0031331 | 128 | 0.016 | |
| nucleoside phosphate metabolic process | GO:0006753 | 458 | 0.016 | |
| mitotic spindle checkpoint | GO:0071174 | 34 | 0.015 | |
| nucleus organization | GO:0006997 | 62 | 0.015 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 289 | 0.015 | |
| positive regulation of protein modification process | GO:0031401 | 49 | 0.015 | |
| regulation of signal transduction | GO:0009966 | 114 | 0.015 | |
| purine ribonucleoside metabolic process | GO:0046128 | 380 | 0.015 | |
| purine nucleotide metabolic process | GO:0006163 | 376 | 0.015 | |
| positive regulation of apoptotic process | GO:0043065 | 3 | 0.015 | |
| negative regulation of cellular protein catabolic process | GO:1903363 | 27 | 0.014 | |
| response to organic substance | GO:0010033 | 182 | 0.014 | Mouse |
| regulation of nucleotide catabolic process | GO:0030811 | 106 | 0.014 | |
| internal protein amino acid acetylation | GO:0006475 | 52 | 0.014 | |
| regulation of transferase activity | GO:0051338 | 83 | 0.014 | |
| protein complex disassembly | GO:0043241 | 70 | 0.014 | |
| reciprocal dna recombination | GO:0035825 | 54 | 0.014 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.014 | |
| amine metabolic process | GO:0009308 | 51 | 0.014 | |
| conjugation | GO:0000746 | 107 | 0.014 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 147 | 0.014 | |
| gene conversion at mating type locus | GO:0007534 | 11 | 0.014 | |
| anatomical structure morphogenesis | GO:0009653 | 160 | 0.014 | Human Mouse Fly |
| negative regulation of phosphate metabolic process | GO:0045936 | 49 | 0.014 | |
| cellular response to organic substance | GO:0071310 | 159 | 0.014 | Mouse |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 224 | 0.014 | |
| protein localization to nucleus | GO:0034504 | 74 | 0.014 | |
| anion transport | GO:0006820 | 145 | 0.013 | |
| trna wobble base modification | GO:0002097 | 27 | 0.013 | |
| dna dependent dna replication maintenance of fidelity | GO:0045005 | 14 | 0.013 | |
| cell cycle g2 m phase transition | GO:0044839 | 39 | 0.013 | |
| phosphatidylcholine metabolic process | GO:0046470 | 20 | 0.013 | |
| regulation of response to stimulus | GO:0048583 | 157 | 0.013 | |
| mitotic recombination | GO:0006312 | 55 | 0.013 | |
| regulation of gene silencing | GO:0060968 | 41 | 0.013 | |
| negative regulation of phosphorus metabolic process | GO:0010563 | 49 | 0.013 | |
| cell cycle phase transition | GO:0044770 | 144 | 0.013 | |
| modification dependent protein catabolic process | GO:0019941 | 181 | 0.012 | |
| regulation of purine nucleotide metabolic process | GO:1900542 | 109 | 0.012 | |
| positive regulation of organelle organization | GO:0010638 | 85 | 0.012 | |
| rna phosphodiester bond hydrolysis | GO:0090501 | 112 | 0.012 | |
| vesicle localization | GO:0051648 | 9 | 0.012 | |
| sister chromatid segregation | GO:0000819 | 93 | 0.012 | |
| g2 m transition of mitotic cell cycle | GO:0000086 | 38 | 0.012 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 356 | 0.012 | |
| regulation of translation | GO:0006417 | 89 | 0.012 | |
| intracellular protein transmembrane import | GO:0044743 | 67 | 0.012 | |
| pyridine containing compound metabolic process | GO:0072524 | 53 | 0.012 | |
| phosphatidylinositol metabolic process | GO:0046488 | 62 | 0.012 | |
| trna modification | GO:0006400 | 75 | 0.012 | |
| spindle assembly checkpoint | GO:0071173 | 23 | 0.012 | |
| regulation of nucleotide metabolic process | GO:0006140 | 110 | 0.012 | |
| dna replication | GO:0006260 | 147 | 0.012 | |
| negative regulation of mitosis | GO:0045839 | 39 | 0.012 | |
| poly a mrna export from nucleus | GO:0016973 | 24 | 0.012 | |
| carboxylic acid biosynthetic process | GO:0046394 | 152 | 0.012 | |
| steroid biosynthetic process | GO:0006694 | 35 | 0.012 | |
| cellular amino acid metabolic process | GO:0006520 | 225 | 0.012 | |
| ascospore formation | GO:0030437 | 107 | 0.011 | |
| spindle checkpoint | GO:0031577 | 35 | 0.011 | |
| sporulation | GO:0043934 | 132 | 0.011 | |
| regulation of dna dependent dna replication | GO:0090329 | 37 | 0.011 | |
| dna catabolic process | GO:0006308 | 42 | 0.011 | |
| trna wobble uridine modification | GO:0002098 | 26 | 0.011 | |
| cell wall organization | GO:0071555 | 146 | 0.011 | |
| cell cycle checkpoint | GO:0000075 | 82 | 0.011 | |
| protein dna complex subunit organization | GO:0071824 | 153 | 0.010 | |
| cellular lipid metabolic process | GO:0044255 | 229 | 0.010 | |
| mitochondrion localization | GO:0051646 | 29 | 0.010 | |
| guanosine containing compound catabolic process | GO:1901069 | 109 | 0.010 | |
| regulation of purine nucleotide catabolic process | GO:0033121 | 106 | 0.010 | |
| nucleoside metabolic process | GO:0009116 | 394 | 0.010 | |
| cellular biogenic amine metabolic process | GO:0006576 | 37 | 0.010 | |
| negative regulation of cytoskeleton organization | GO:0051494 | 24 | 0.010 | |
| iron sulfur cluster assembly | GO:0016226 | 22 | 0.010 | |
| regulation of nucleoside metabolic process | GO:0009118 | 106 | 0.010 | |