Saccharomyces cerevisiae

158 known processes

TOP2 (YNL088W)

Top2p

(Aliases: TRF3,TOR3)

TOP2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
mitotic cell cycle processGO:19030472940.806
mitotic cell cycleGO:00002783060.560
dna repairGO:00062812360.463
positive regulation of macromolecule biosynthetic processGO:00105573250.372
Mouse
nuclear divisionGO:00002802630.340
positive regulation of rna biosynthetic processGO:19026802860.286
Mouse
nucleoside phosphate metabolic processGO:00067534580.249
positive regulation of gene expressionGO:00106283210.231
Mouse
dna conformation changeGO:0071103980.217
positive regulation of transcription dna templatedGO:00458932860.212
Mouse
positive regulation of nitrogen compound metabolic processGO:00511734120.202
Human Mouse
protein localization to nucleusGO:0034504740.190
positive regulation of rna metabolic processGO:00512542940.186
Human Mouse
organelle fissionGO:00482852720.160
negative regulation of macromolecule metabolic processGO:00106053750.150
Worm
g2 m transition of mitotic cell cycleGO:0000086380.149
positive regulation of macromolecule metabolic processGO:00106043940.144
Human Mouse
cellular response to dna damage stimulusGO:00069742870.136
Human
macromolecule catabolic processGO:00090573830.131
cell cycle checkpointGO:0000075820.129
negative regulation of cellular macromolecule biosynthetic processGO:20001132890.127
aromatic compound catabolic processGO:00194394910.127
nucleoside catabolic processGO:00091643350.125
regulation of cellular protein metabolic processGO:00322682320.116
positive regulation of transcription from rna polymerase ii promoterGO:00459442520.115
Mouse
response to chemicalGO:00422213900.113
cell cycle phase transitionGO:00447701440.113
protein catabolic processGO:00301632210.111
positive regulation of nucleic acid templated transcriptionGO:19035082860.110
Mouse
organophosphate metabolic processGO:00196375970.109
meiotic cell cycleGO:00513212720.108
microtubule based processGO:00070171170.107
mitotic nuclear divisionGO:00070671310.106
purine nucleotide metabolic processGO:00061633760.104
regulation of cell cycle processGO:00105641500.103
negative regulation of biosynthetic processGO:00098903120.099
negative regulation of gene expressionGO:00106293120.098
Worm
positive regulation of cellular biosynthetic processGO:00313283360.098
Mouse
ribonucleotide metabolic processGO:00092593770.096
mrna metabolic processGO:00160712690.095
regulation of transcription from rna polymerase ii promoterGO:00063573940.091
Mouse
mitotic cell cycle phase transitionGO:00447721410.090
nucleocytoplasmic transportGO:00069131630.086
negative regulation of cell cycle processGO:0010948860.085
regulation of cell cycleGO:00517261950.085
protein complex assemblyGO:00064613020.085
protein localization to organelleGO:00333653370.084
nucleobase containing compound catabolic processGO:00346554790.081
purine nucleoside triphosphate catabolic processGO:00091463290.074
purine ribonucleoside metabolic processGO:00461283800.072
negative regulation of cellular biosynthetic processGO:00313273120.070
organonitrogen compound catabolic processGO:19015654040.067
carbohydrate derivative metabolic processGO:19011355490.066
negative regulation of gene expression epigeneticGO:00458141470.065
nuclear transportGO:00511691650.065
regulation of biological qualityGO:00650083910.063
positive regulation of nucleobase containing compound metabolic processGO:00459354090.061
Human Mouse
mrna processingGO:00063971850.061
regulation of protein metabolic processGO:00512462370.061
cytoskeleton organizationGO:00070102300.060
glycosyl compound catabolic processGO:19016583350.059
heterocycle catabolic processGO:00467004940.056
gene silencingGO:00164581510.054
Worm
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:00003771090.053
negative regulation of transcription dna templatedGO:00458922580.052
purine nucleoside metabolic processGO:00422783800.052
microtubule cytoskeleton organizationGO:00002261090.051
ribonucleoside metabolic processGO:00091193890.050
positive regulation of dna templated transcription elongationGO:0032786420.050
regulation of protein modification processGO:00313991100.049
dna replicationGO:00062601470.047
regulation of organelle organizationGO:00330432430.047
cellular amine metabolic processGO:0044106510.047
methylationGO:00322591010.045
cellular macromolecule catabolic processGO:00442653630.044
mitotic cell cycle checkpointGO:0007093560.043
organic cyclic compound catabolic processGO:19013614990.043
purine ribonucleoside monophosphate metabolic processGO:00091672620.043
ubiquitin dependent protein catabolic processGO:00065111810.043
nucleobase containing small molecule metabolic processGO:00550864910.043
rna splicingGO:00083801310.040
protein complex biogenesisGO:00702713140.040
amine metabolic processGO:0009308510.040
proteolysisGO:00065082680.040
phosphorylationGO:00163102910.040
response to abiotic stimulusGO:00096281590.039
regulation of cellular component organizationGO:00511283340.039
single organism catabolic processGO:00447126190.038
purine ribonucleoside triphosphate metabolic processGO:00092053540.038
nucleotide metabolic processGO:00091174530.038
meiotic nuclear divisionGO:00071261630.037
modification dependent macromolecule catabolic processGO:00436322030.037
glycosyl compound metabolic processGO:19016573980.036
negative regulation of mitotic cell cycle phase transitionGO:1901991570.033
negative regulation of cell cycleGO:0045786910.033
positive regulation of cellular protein metabolic processGO:0032270890.033
negative regulation of macromolecule biosynthetic processGO:00105582910.033
cellular response to abiotic stimulusGO:0071214620.032
ribonucleoside triphosphate metabolic processGO:00091993560.032
cellular protein catabolic processGO:00442572130.032
atp catabolic processGO:00062002240.032
negative regulation of protein metabolic processGO:0051248850.032
regulation of cell divisionGO:00513021130.032
response to oxidative stressGO:0006979990.031
establishment of protein localization to organelleGO:00725942780.031
positive regulation of biosynthetic processGO:00098913360.031
Mouse
positive regulation of protein metabolic processGO:0051247930.031
negative regulation of chromosome organizationGO:2001251390.030
cellular nitrogen compound catabolic processGO:00442704940.030
negative regulation of nitrogen compound metabolic processGO:00511723000.030
nucleoside phosphate biosynthetic processGO:1901293800.029
nucleus localizationGO:0051647220.028
growth of unicellular organism as a thread of attached cellsGO:00707831050.028
response to uvGO:000941140.028
dna dependent dna replicationGO:00062611150.027
purine nucleoside monophosphate catabolic processGO:00091282240.027
atp metabolic processGO:00460342510.027
negative regulation of nucleic acid templated transcriptionGO:19035072600.026
regulation of protein localizationGO:0032880620.026
nucleoside metabolic processGO:00091163940.026
posttranscriptional regulation of gene expressionGO:00106081150.026
Worm
ribonucleoside triphosphate catabolic processGO:00092033270.026
chromatin remodelingGO:0006338800.026
nucleoside monophosphate catabolic processGO:00091252240.026
nucleotide catabolic processGO:00091663300.026
cell wall organization or biogenesisGO:00715541900.025
purine nucleoside catabolic processGO:00061523300.025
cell differentiationGO:00301541610.025
Mouse
cell communicationGO:00071543450.025
purine ribonucleotide catabolic processGO:00091543270.025
developmental process involved in reproductionGO:00030061590.024
regulation of catabolic processGO:00098941990.024
septin ring assemblyGO:0000921140.024
organophosphate catabolic processGO:00464343380.023
double strand break repairGO:00063021050.023
purine nucleotide catabolic processGO:00061953280.023
cellular ketone metabolic processGO:0042180630.022
ribonucleoside monophosphate metabolic processGO:00091612650.022
positive regulation of cellular catabolic processGO:00313311280.022
ribonucleotide catabolic processGO:00092613270.022
multi organism reproductive processGO:00447032160.022
protein processingGO:0016485640.021
regulation of dna metabolic processGO:00510521000.021
regulation of cellular component biogenesisGO:00440871120.021
mrna 3 end processingGO:0031124540.020
regulation of gene expression epigeneticGO:00400291470.020
Worm
cellular protein complex assemblyGO:00436232090.020
response to heatGO:0009408690.020
chromatin silencing at silent mating type cassetteGO:0030466530.020
regulation of dna templated transcription elongationGO:0032784440.020
nucleoside phosphate catabolic processGO:19012923310.020
negative regulation of cellular metabolic processGO:00313244070.020
mrna splicing via spliceosomeGO:00003981080.019
nucleic acid phosphodiester bond hydrolysisGO:00903051940.019
ribose phosphate metabolic processGO:00196933840.019
intracellular protein transportGO:00068863190.019
negative regulation of cellular component organizationGO:00511291090.019
protein modification by small protein conjugationGO:00324461440.018
dna strand elongationGO:0022616290.018
positive regulation of programmed cell deathGO:004306830.018
Human
external encapsulating structure organizationGO:00452291460.018
single organism nuclear importGO:1902593560.018
regulation of cellular amino acid metabolic processGO:0006521160.018
regulation of nuclear divisionGO:00517831030.018
chemical homeostasisGO:00488781370.018
protein targeting to nucleusGO:0044744570.017
dna integrity checkpointGO:0031570410.017
carbohydrate derivative catabolic processGO:19011363390.017
nucleoside triphosphate metabolic processGO:00091413640.017
regulation of cellular catabolic processGO:00313291950.017
purine ribonucleoside triphosphate catabolic processGO:00092073270.017
organic acid metabolic processGO:00060823520.017
negative regulation of protein catabolic processGO:0042177270.017
dna packagingGO:0006323550.017
Human Mouse
cell cycle g2 m phase transitionGO:0044839390.016
positive regulation of catalytic activityGO:00430851780.016
generation of precursor metabolites and energyGO:00060911470.016
nucleosome assemblyGO:0006334160.016
cell growthGO:0016049890.016
transcription elongation from rna polymerase ii promoterGO:0006368810.016
regulation of molecular functionGO:00650093200.016
reproductive processGO:00224142480.016
purine ribonucleoside monophosphate catabolic processGO:00091692240.016
cell agingGO:0007569700.016
single organism developmental processGO:00447672580.016
Mouse Worm
negative regulation of cellular protein metabolic processGO:0032269850.016
negative regulation of rna biosynthetic processGO:19026792600.015
regulation of response to stimulusGO:00485831570.015
negative regulation of organelle organizationGO:00106391030.015
positive regulation of organelle organizationGO:0010638850.015
dna recombinationGO:00063101720.015
nucleotide biosynthetic processGO:0009165790.015
ribonucleoside monophosphate catabolic processGO:00091582240.015
reproduction of a single celled organismGO:00325051910.014
sexual reproductionGO:00199532160.014
protein import into nucleusGO:0006606550.014
regulation of gene silencingGO:0060968410.014
protein modification by small protein conjugation or removalGO:00706471720.014
alcohol metabolic processGO:00060661120.014
protein acetylationGO:0006473590.014
regulation of protein phosphorylationGO:0001932750.014
cellular response to chemical stimulusGO:00708873150.014
protein dna complex subunit organizationGO:00718241530.014
chromatin assemblyGO:0031497350.014
nucleoside triphosphate catabolic processGO:00091433290.014
protein phosphorylationGO:00064681970.014
rna splicing via transesterification reactionsGO:00003751180.014
regulation of cellular amine metabolic processGO:0033238210.014
developmental processGO:00325022610.013
Mouse Worm
lipid metabolic processGO:00066292690.013
regulation of rna splicingGO:004348430.013
positive regulation of cell cycleGO:0045787320.013
negative regulation of mitotic cell cycleGO:0045930630.013
cellular response to oxidative stressGO:0034599940.013
positive regulation of transcription elongation from rna polymerase ii promoterGO:0032968380.013
meiosis iGO:0007127920.013
fungal type cell wall organization or biogenesisGO:00718521690.013
positive regulation of protein complex assemblyGO:0031334390.013
maintenance of locationGO:0051235660.013
negative regulation of nucleobase containing compound metabolic processGO:00459342950.013
chromatin assembly or disassemblyGO:0006333600.013
nuclear importGO:0051170570.013
lipid localizationGO:0010876600.012
positive regulation of sequence specific dna binding transcription factor activityGO:005109120.012
single organism reproductive processGO:00447021590.012
pseudohyphal growthGO:0007124750.012
cell wall organizationGO:00715551460.012
growthGO:00400071570.012
positive regulation of catabolic processGO:00098961350.012
membrane organizationGO:00610242760.012
signalingGO:00230522080.012
regulation of cellular ketone metabolic processGO:0010565420.012
protein transportGO:00150313450.012
negative regulation of cell cycle phase transitionGO:1901988590.012
positive regulation of cellular component organizationGO:00511301160.011
positive regulation of apoptotic processGO:004306530.011
Human
nucleosome organizationGO:0034728630.011
regulation of transcription by chromatin organizationGO:0034401190.011
regulation of catalytic activityGO:00507903070.011
chromosome separationGO:0051304330.011
chromatin organizationGO:00063252420.011
multi organism processGO:00517042330.011
Human
protein ubiquitinationGO:00165671180.011
regulation of cell cycle phase transitionGO:1901987700.011
cellular chemical homeostasisGO:00550821230.011
reciprocal meiotic recombinationGO:0007131540.010
proteolysis involved in cellular protein catabolic processGO:00516031980.010
covalent chromatin modificationGO:00165691190.010
anatomical structure developmentGO:00488561600.010
Mouse Worm
oxidation reduction processGO:00551143530.010
purine containing compound catabolic processGO:00725233320.010

TOP2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org