IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

67 known processes

PMI40 (YER003C)

Pmi40p

SGD: S000000805
Entrez: 856720
UniProtKB: P29952

Process Predictions
Disease Predictions

PMI40 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
glycosylation	GO:0070085	66	0.713
macromolecule glycosylation	GO:0043413	57	0.711
protein glycosylation	GO:0006486	57	0.666
carbohydrate derivative metabolic process	GO:1901135	549	0.657
single organism carbohydrate metabolic process	GO:0044723	237	0.652
glycoprotein metabolic process	GO:0009100	62	0.632
carbohydrate derivative biosynthetic process	GO:1901137	181	0.580
nucleotide biosynthetic process	GO:0009165	79	0.575
nucleotide metabolic process	GO:0009117	453	0.463
glycoprotein biosynthetic process	GO:0009101	61	0.425
carbohydrate metabolic process	GO:0005975	252	0.386
nucleoside phosphate metabolic process	GO:0006753	458	0.362
organophosphate biosynthetic process	GO:0090407	182	0.358
organophosphate metabolic process	GO:0019637	597	0.307
nucleobase containing small molecule metabolic process	GO:0055086	491	0.305
single organism catabolic process	GO:0044712	619	0.251
nucleobase containing compound catabolic process	GO:0034655	479	0.248
protein n linked glycosylation	GO:0006487	34	0.246
cellular nitrogen compound catabolic process	GO:0044270	494	0.230
organonitrogen compound biosynthetic process	GO:1901566	314	0.215
carboxylic acid metabolic process	GO:0019752	338	0.208
nitrogen compound transport	GO:0071705	212	0.205
ion transport	GO:0006811	274	0.204
organophosphate ester transport	GO:0015748	45	0.203
organic cyclic compound catabolic process	GO:1901361	499	0.200
pyridine nucleotide metabolic process	GO:0019362	45	0.185
cofactor metabolic process	GO:0051186	126	0.165
membrane budding	GO:0006900	22	0.165
pyrimidine containing compound metabolic process	GO:0072527	37	0.164
nicotinamide nucleotide metabolic process	GO:0046496	44	0.164
glycosyl compound metabolic process	GO:1901657	398	0.155
ribonucleoside catabolic process	GO:0042454	332	0.145
negative regulation of cellular metabolic process	GO:0031324	407	0.132
oxoacid metabolic process	GO:0043436	351	0.130
oligosaccharide metabolic process	GO:0009311	35	0.130
negative regulation of biosynthetic process	GO:0009890	312	0.127
pyridine containing compound metabolic process	GO:0072524	53	0.127
nucleoside metabolic process	GO:0009116	394	0.126
organic acid biosynthetic process	GO:0016053	152	0.120
cellular response to extracellular stimulus	GO:0031668	150	0.118
intracellular protein transport	GO:0006886	319	0.114
coenzyme biosynthetic process	GO:0009108	66	0.112
cofactor biosynthetic process	GO:0051188	80	0.112
generation of precursor metabolites and energy	GO:0006091	147	0.111
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.111
oxidoreduction coenzyme metabolic process	GO:0006733	58	0.110
organonitrogen compound catabolic process	GO:1901565	404	0.103
positive regulation of macromolecule metabolic process	GO:0010604	394	0.100
purine ribonucleoside metabolic process	GO:0046128	380	0.100
cellular lipid metabolic process	GO:0044255	229	0.099
aromatic compound catabolic process	GO:0019439	491	0.099
purine containing compound metabolic process	GO:0072521	400	0.089
small molecule biosynthetic process	GO:0044283	258	0.087
nucleoside triphosphate metabolic process	GO:0009141	364	0.084
establishment of protein localization	GO:0045184	367	0.082
membrane organization	GO:0061024	276	0.079
establishment of organelle localization	GO:0051656	96	0.077
vesicle organization	GO:0016050	68	0.076
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.076
cellular chemical homeostasis	GO:0055082	123	0.074
purine nucleoside metabolic process	GO:0042278	380	0.072
purine containing compound catabolic process	GO:0072523	332	0.071
heterocycle catabolic process	GO:0046700	494	0.070
protein transport	GO:0015031	345	0.068
nucleoside catabolic process	GO:0009164	335	0.068
ribonucleoside metabolic process	GO:0009119	389	0.067
phosphatidylinositol metabolic process	GO:0046488	62	0.066
organic acid metabolic process	GO:0006082	352	0.066
regulation of phosphorus metabolic process	GO:0051174	230	0.065
nucleoside phosphate biosynthetic process	GO:1901293	80	0.064
homeostatic process	GO:0042592	227	0.059
methylation	GO:0032259	101	0.058
coenzyme metabolic process	GO:0006732	104	0.058
divalent inorganic cation homeostasis	GO:0072507	21	0.058
glycosyl compound catabolic process	GO:1901658	335	0.056
cellular ion homeostasis	GO:0006873	112	0.054
protein export from nucleus	GO:0006611	17	0.053
purine nucleotide metabolic process	GO:0006163	376	0.053
post golgi vesicle mediated transport	GO:0006892	72	0.052
cellular divalent inorganic cation homeostasis	GO:0072503	21	0.051
actin cytoskeleton organization	GO:0030036	100	0.049
regulation of phosphate metabolic process	GO:0019220	230	0.049
purine ribonucleotide catabolic process	GO:0009154	327	0.049
macromolecule methylation	GO:0043414	85	0.049
nuclear export	GO:0051168	124	0.047
cell communication	GO:0007154	345	0.046
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.046
ribonucleotide metabolic process	GO:0009259	377	0.046
lipid biosynthetic process	GO:0008610	170	0.046
carbohydrate derivative catabolic process	GO:1901136	339	0.045
lipid metabolic process	GO:0006629	269	0.044
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.044
ribose phosphate metabolic process	GO:0019693	384	0.044
regulation of biological quality	GO:0065008	391	0.043
nuclear transport	GO:0051169	165	0.043
cellular response to chemical stimulus	GO:0070887	315	0.042
monocarboxylic acid metabolic process	GO:0032787	122	0.042
protein o linked glycosylation	GO:0006493	15	0.042
nucleobase containing compound transport	GO:0015931	124	0.041
carboxylic acid biosynthetic process	GO:0046394	152	0.041
nucleotide catabolic process	GO:0009166	330	0.040
fungal type cell wall organization or biogenesis	GO:0071852	169	0.040
single organism cellular localization	GO:1902580	375	0.040
cellular developmental process	GO:0048869	191	0.040
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.039
rrna metabolic process	GO:0016072	244	0.039
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.039
ribonucleotide catabolic process	GO:0009261	327	0.038
golgi vesicle transport	GO:0048193	188	0.038
fungal type cell wall organization	GO:0031505	145	0.037
signaling	GO:0023052	208	0.037
purine ribonucleoside catabolic process	GO:0046130	330	0.037
oxidation reduction process	GO:0055114	353	0.037
cellular response to dna damage stimulus	GO:0006974	287	0.037
aerobic respiration	GO:0009060	55	0.036
establishment of protein localization to membrane	GO:0090150	99	0.036
single organism carbohydrate catabolic process	GO:0044724	73	0.036
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.036
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.036
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.035
glycerophospholipid biosynthetic process	GO:0046474	68	0.035
regulation of purine nucleotide metabolic process	GO:1900542	109	0.035
alpha amino acid metabolic process	GO:1901605	124	0.035
purine ribonucleotide metabolic process	GO:0009150	372	0.035
rna 3 end processing	GO:0031123	88	0.034
anion transport	GO:0006820	145	0.034
organelle localization	GO:0051640	128	0.034
regulation of signal transduction	GO:0009966	114	0.034
negative regulation of gene expression	GO:0010629	312	0.034
nucleoside triphosphate catabolic process	GO:0009143	329	0.034
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.033
cation transport	GO:0006812	166	0.033
phospholipid metabolic process	GO:0006644	125	0.033
regulation of catabolic process	GO:0009894	199	0.032
maintenance of location	GO:0051235	66	0.032
regulation of nuclear division	GO:0051783	103	0.032
pyrimidine containing compound biosynthetic process	GO:0072528	33	0.032
sporulation	GO:0043934	132	0.032
cell cycle checkpoint	GO:0000075	82	0.032
cellular homeostasis	GO:0019725	138	0.031
macromolecule catabolic process	GO:0009057	383	0.031
regulation of purine nucleotide catabolic process	GO:0033121	106	0.031
endomembrane system organization	GO:0010256	74	0.031
actin filament based process	GO:0030029	104	0.030
gtp metabolic process	GO:0046039	107	0.030
chromatin silencing	GO:0006342	147	0.030
purine nucleoside catabolic process	GO:0006152	330	0.030
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.030
gene silencing	GO:0016458	151	0.030
reproductive process	GO:0022414	248	0.030
cellular respiration	GO:0045333	82	0.029
regulation of response to stimulus	GO:0048583	157	0.029
negative regulation of cellular biosynthetic process	GO:0031327	312	0.029
purine nucleotide catabolic process	GO:0006195	328	0.029
response to nutrient levels	GO:0031667	150	0.029
phospholipid biosynthetic process	GO:0008654	89	0.029
amine metabolic process	GO:0009308	51	0.028
cell wall organization	GO:0071555	146	0.028
cellular cation homeostasis	GO:0030003	100	0.028
regulation of nucleotide metabolic process	GO:0006140	110	0.028
tetrapyrrole metabolic process	GO:0033013	15	0.028
cellular metal ion homeostasis	GO:0006875	78	0.027
cation homeostasis	GO:0055080	105	0.027
organophosphate catabolic process	GO:0046434	338	0.027
porphyrin containing compound metabolic process	GO:0006778	15	0.027
meiotic cell cycle process	GO:1903046	229	0.026
cellular carbohydrate metabolic process	GO:0044262	135	0.026
protein localization to endoplasmic reticulum	GO:0070972	47	0.026
gtp catabolic process	GO:0006184	107	0.026
glycerolipid biosynthetic process	GO:0045017	71	0.026
cellular amine metabolic process	GO:0044106	51	0.026
establishment of protein localization to organelle	GO:0072594	278	0.025
vacuolar transport	GO:0007034	145	0.025
regulation of gtp catabolic process	GO:0033124	84	0.025
external encapsulating structure organization	GO:0045229	146	0.025
regulation of gtpase activity	GO:0043087	84	0.025
regulation of cell communication	GO:0010646	124	0.025
positive regulation of transcription dna templated	GO:0045893	286	0.025
negative regulation of rna metabolic process	GO:0051253	262	0.025
developmental process involved in reproduction	GO:0003006	159	0.025
cellular macromolecule catabolic process	GO:0044265	363	0.025
multi organism reproductive process	GO:0044703	216	0.025
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.024
response to chemical	GO:0042221	390	0.024
carbohydrate derivative transport	GO:1901264	27	0.023
energy derivation by oxidation of organic compounds	GO:0015980	125	0.023
cellular protein catabolic process	GO:0044257	213	0.022
tetrapyrrole biosynthetic process	GO:0033014	14	0.022
filamentous growth of a population of unicellular organisms	GO:0044182	109	0.022
establishment of protein localization to vacuole	GO:0072666	91	0.022
guanosine containing compound catabolic process	GO:1901069	109	0.022
organelle inheritance	GO:0048308	51	0.021
hexose metabolic process	GO:0019318	78	0.021
regulation of cellular ketone metabolic process	GO:0010565	42	0.021
response to external stimulus	GO:0009605	158	0.021
anatomical structure homeostasis	GO:0060249	74	0.021
regulation of nucleotide catabolic process	GO:0030811	106	0.021
positive regulation of gene expression	GO:0010628	321	0.021
nucleocytoplasmic transport	GO:0006913	163	0.021
glutamine family amino acid biosynthetic process	GO:0009084	18	0.021
chemical homeostasis	GO:0048878	137	0.021
nad metabolic process	GO:0019674	25	0.021
metal ion homeostasis	GO:0055065	79	0.021
rrna containing ribonucleoprotein complex export from nucleus	GO:0071428	46	0.021
ion homeostasis	GO:0050801	118	0.020
single organism signaling	GO:0044700	208	0.020
mrna processing	GO:0006397	185	0.020
regulation of cellular catabolic process	GO:0031329	195	0.020
regulation of protein metabolic process	GO:0051246	237	0.020
mrna metabolic process	GO:0016071	269	0.020
cellular modified amino acid metabolic process	GO:0006575	51	0.019
regulation of hydrolase activity	GO:0051336	133	0.019
dna conformation change	GO:0071103	98	0.019
maintenance of location in cell	GO:0051651	58	0.019
regulation of nucleoside metabolic process	GO:0009118	106	0.019
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.019
regulation of metal ion transport	GO:0010959	2	0.019
mitochondrion organization	GO:0007005	261	0.019
nucleotide transport	GO:0006862	19	0.019
regulation of localization	GO:0032879	127	0.019
monocarboxylic acid biosynthetic process	GO:0072330	35	0.019
regulation of lipid metabolic process	GO:0019216	45	0.018
glutamine family amino acid metabolic process	GO:0009064	31	0.018
ribosome localization	GO:0033750	46	0.018
filamentous growth	GO:0030447	124	0.018
ras protein signal transduction	GO:0007265	29	0.018
misfolded or incompletely synthesized protein catabolic process	GO:0006515	21	0.018
regulation of cell division	GO:0051302	113	0.018
er to golgi vesicle mediated transport	GO:0006888	86	0.017
glycerophospholipid metabolic process	GO:0006650	98	0.017
glycerolipid metabolic process	GO:0046486	108	0.017
golgi to vacuole transport	GO:0006896	23	0.017
protein localization to vacuole	GO:0072665	92	0.017
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.017
single organism reproductive process	GO:0044702	159	0.017
signal transduction	GO:0007165	208	0.017
cellular ketone metabolic process	GO:0042180	63	0.017
nucleoside phosphate catabolic process	GO:1901292	331	0.017
dephosphorylation	GO:0016311	127	0.017
lipid localization	GO:0010876	60	0.017
anatomical structure development	GO:0048856	160	0.016
protein catabolic process	GO:0030163	221	0.016
single organism developmental process	GO:0044767	258	0.016
secretion by cell	GO:0032940	50	0.016
negative regulation of phosphate metabolic process	GO:0045936	49	0.016
ethanolamine containing compound metabolic process	GO:0042439	21	0.016
fatty acid biosynthetic process	GO:0006633	22	0.016
adenine nucleotide transport	GO:0051503	7	0.016
protein alkylation	GO:0008213	48	0.015
single organism membrane organization	GO:0044802	275	0.015
regulation of cellular amine metabolic process	GO:0033238	21	0.015
cellular amino acid biosynthetic process	GO:0008652	118	0.015
protein complex biogenesis	GO:0070271	314	0.015
negative regulation of rna biosynthetic process	GO:1902679	260	0.015
positive regulation of molecular function	GO:0044093	185	0.015
atp metabolic process	GO:0046034	251	0.015
carbon catabolite regulation of transcription from rna polymerase ii promoter	GO:0000429	34	0.015
response to organic substance	GO:0010033	182	0.015
purine nucleoside monophosphate metabolic process	GO:0009126	262	0.014
carboxylic acid catabolic process	GO:0046395	71	0.014
protein dna complex subunit organization	GO:0071824	153	0.014
negative regulation of cell cycle process	GO:0010948	86	0.014
cellular amino acid metabolic process	GO:0006520	225	0.014
response to abiotic stimulus	GO:0009628	159	0.014
positive regulation of secretion by cell	GO:1903532	2	0.014
srp dependent cotranslational protein targeting to membrane translocation	GO:0006616	9	0.014
regulation of intracellular signal transduction	GO:1902531	78	0.014
maintenance of protein location	GO:0045185	53	0.014
nucleoside transport	GO:0015858	14	0.014
protein localization to organelle	GO:0033365	337	0.014
rna localization	GO:0006403	112	0.014
protein o linked mannosylation	GO:0035269	7	0.014
protein targeting	GO:0006605	272	0.014
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	109	0.014
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.014
regulation of cell cycle	GO:0051726	195	0.014
negative regulation of gene expression epigenetic	GO:0045814	147	0.014
telomere maintenance	GO:0000723	74	0.014
nicotinamide nucleotide biosynthetic process	GO:0019359	16	0.014
ribosomal subunit export from nucleus	GO:0000054	46	0.014
nucleoside monophosphate metabolic process	GO:0009123	267	0.014
regulation of ras protein signal transduction	GO:0046578	47	0.014
heme metabolic process	GO:0042168	15	0.014
phosphorylation	GO:0016310	291	0.014
er nucleus signaling pathway	GO:0006984	23	0.013
invasive growth in response to glucose limitation	GO:0001403	61	0.013
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.013
sexual reproduction	GO:0019953	216	0.013
conjugation	GO:0000746	107	0.013
response to starvation	GO:0042594	96	0.013
carbon catabolite regulation of transcription	GO:0045990	39	0.013
response to unfolded protein	GO:0006986	29	0.013
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.013
cellular response to topologically incorrect protein	GO:0035967	32	0.013
regulation of cellular component organization	GO:0051128	334	0.013
proton transport	GO:0015992	61	0.013
rna splicing	GO:0008380	131	0.013
growth	GO:0040007	157	0.013
glucose metabolic process	GO:0006006	65	0.013
cell division	GO:0051301	205	0.013
cation transmembrane transport	GO:0098655	135	0.013
cellular response to organic substance	GO:0071310	159	0.013
rna transport	GO:0050658	92	0.013
positive regulation of intracellular protein transport	GO:0090316	3	0.013
positive regulation of hydrolase activity	GO:0051345	112	0.013
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.013
protein modification by small protein conjugation	GO:0032446	144	0.013
porphyrin containing compound biosynthetic process	GO:0006779	14	0.013
response to extracellular stimulus	GO:0009991	156	0.013
rrna processing	GO:0006364	227	0.012
sexual sporulation	GO:0034293	113	0.012
inorganic ion transmembrane transport	GO:0098660	109	0.012
golgi to plasma membrane transport	GO:0006893	33	0.012
regulation of signaling	GO:0023051	119	0.012
retrograde protein transport er to cytosol	GO:0030970	8	0.012
positive regulation of cytoplasmic transport	GO:1903651	4	0.012
small gtpase mediated signal transduction	GO:0007264	36	0.012
carbohydrate catabolic process	GO:0016052	77	0.012
establishment of protein localization to endoplasmic reticulum	GO:0072599	40	0.012
mitochondrial genome maintenance	GO:0000002	40	0.012
response to topologically incorrect protein	GO:0035966	38	0.012
cellular response to nutrient	GO:0031670	50	0.012
regulation of mitosis	GO:0007088	65	0.012
positive regulation of phosphate metabolic process	GO:0045937	147	0.012
positive regulation of catabolic process	GO:0009896	135	0.012
protein targeting to er	GO:0045047	39	0.012
vacuole organization	GO:0007033	75	0.012
cellular component morphogenesis	GO:0032989	97	0.012
regulation of cell cycle process	GO:0010564	150	0.012
membrane lipid biosynthetic process	GO:0046467	54	0.012
positive regulation of phosphorus metabolic process	GO:0010562	147	0.012
regulation of catalytic activity	GO:0050790	307	0.012
deoxyribonucleotide biosynthetic process	GO:0009263	7	0.012
cellular response to external stimulus	GO:0071496	150	0.011
protein import into nucleus	GO:0006606	55	0.011
dolichol linked oligosaccharide biosynthetic process	GO:0006488	11	0.011
rna methylation	GO:0001510	39	0.011
protein localization to membrane	GO:0072657	102	0.011
mitotic cell cycle process	GO:1903047	294	0.011
multi organism cellular process	GO:0044764	120	0.011
mitotic cell cycle	GO:0000278	306	0.011
regulation of transporter activity	GO:0032409	1	0.011
ion transmembrane transport	GO:0034220	200	0.011
chromatin organization	GO:0006325	242	0.011
histone lysine methylation	GO:0034968	26	0.011
cellular response to oxidative stress	GO:0034599	94	0.011
dna integrity checkpoint	GO:0031570	41	0.011
establishment of rna localization	GO:0051236	92	0.011
guanosine containing compound metabolic process	GO:1901068	111	0.011
establishment of vesicle localization	GO:0051650	9	0.011
ribonucleoprotein complex export from nucleus	GO:0071426	46	0.011
cytoskeleton organization	GO:0007010	230	0.011
nadp metabolic process	GO:0006739	16	0.011
regulation of anatomical structure morphogenesis	GO:0022603	17	0.011
regulation of cellular response to stress	GO:0080135	50	0.011
protein localization to nucleus	GO:0034504	74	0.010
alpha amino acid biosynthetic process	GO:1901607	91	0.010
maintenance of protein location in cell	GO:0032507	50	0.010
response to nutrient	GO:0007584	52	0.010
invasive filamentous growth	GO:0036267	65	0.010
protein mannosylation	GO:0035268	7	0.010
protein import	GO:0017038	122	0.010
negative regulation of transcription dna templated	GO:0045892	258	0.010
phosphatidylcholine biosynthetic process	GO:0006656	18	0.010

PMI40 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.016

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