Saccharomyces cerevisiae

123 known processes

LHS1 (YKL073W)

Lhs1p

(Aliases: SSI1,CER1)

LHS1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane transportGO:00550853490.835
protein localization to endoplasmic reticulumGO:0070972470.650
protein targetingGO:00066052720.526
protein targeting to erGO:0045047390.497
signal transductionGO:00071652080.489
Mouse
single organism cellular localizationGO:19025803750.303
protein modification by small protein conjugation or removalGO:00706471720.288
Mouse
signalingGO:00230522080.280
Mouse
ubiquitin dependent protein catabolic processGO:00065111810.279
Yeast
response to chemicalGO:00422213900.266
protein modification by small protein conjugationGO:00324461440.256
Mouse
establishment of protein localization to organelleGO:00725942780.253
proteasomal protein catabolic processGO:00104981410.240
Yeast
establishment of protein localization to endoplasmic reticulumGO:0072599400.237
sexual reproductionGO:00199532160.219
Yeast
single organism membrane organizationGO:00448022750.216
er associated ubiquitin dependent protein catabolic processGO:0030433460.208
Yeast
intracellular protein transportGO:00068863190.206
multi organism cellular processGO:00447641200.197
Yeast
protein foldingGO:0006457940.196
establishment of organelle localizationGO:0051656960.192
cell communicationGO:00071543450.190
Human Mouse
conjugationGO:00007461070.187
Yeast
single organism signalingGO:00447002080.184
Mouse
modification dependent macromolecule catabolic processGO:00436322030.180
Yeast
modification dependent protein catabolic processGO:00199411810.175
Yeast
protein transportGO:00150313450.167
response to organic substanceGO:00100331820.164
multi organism processGO:00517042330.164
Yeast
carbohydrate derivative metabolic processGO:19011355490.164
multi organism reproductive processGO:00447032160.161
Yeast
protein ubiquitinationGO:00165671180.160
Mouse
regulation of map kinase activityGO:0043405120.159
regulation of molecular functionGO:00650093200.159
negative regulation of signal transductionGO:0009968300.156
Mouse
establishment of protein localizationGO:00451843670.151
response to topologically incorrect proteinGO:0035966380.146
organelle localizationGO:00516401280.139
cell wall organization or biogenesisGO:00715541900.137
protein folding in endoplasmic reticulumGO:0034975130.137
regulation of cell communicationGO:00106461240.122
Mouse
peptidyl amino acid modificationGO:00181931160.122
regulation of cellular component biogenesisGO:00440871120.121
negative regulation of cell communicationGO:0010648330.120
Mouse
regulation of protein serine threonine kinase activityGO:0071900410.119
protein localization to membraneGO:00726571020.115
regulation of protein kinase activityGO:0045859670.113
Mouse
cellular macromolecule catabolic processGO:00442653630.112
Yeast Mouse
protein targeting to membraneGO:0006612520.112
membrane organizationGO:00610242760.111
regulation of response to stimulusGO:00485831570.111
Mouse
regulation of localizationGO:00328791270.110
Human
conjugation with cellular fusionGO:00007471060.108
Yeast
signal transduction by phosphorylationGO:0023014310.107
regulation of biological qualityGO:00650083910.107
Human
vesicle organizationGO:0016050680.104
regulation of transferase activityGO:0051338830.103
Mouse
regulation of cellular response to stressGO:0080135500.103
establishment of protein localization to membraneGO:0090150990.101
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611370.100
Yeast
regulation of catalytic activityGO:00507903070.099
negative regulation of intracellular signal transductionGO:1902532270.098
protein localization to organelleGO:00333653370.094
microtubule based processGO:00070171170.092
Fly
vesicle mediated transportGO:00161923350.090
negative regulation of nucleobase containing compound metabolic processGO:00459342950.090
reproductive processGO:00224142480.089
Yeast
negative regulation of response to stimulusGO:0048585400.089
Mouse
heterocycle catabolic processGO:00467004940.088
cellular lipid metabolic processGO:00442552290.088
mitotic cell cycleGO:00002783060.087
carbohydrate derivative biosynthetic processGO:19011371810.087
negative regulation of molecular functionGO:0044092680.086
nitrogen compound transportGO:00717052120.086
regulation of mapk cascadeGO:0043408220.082
negative regulation of macromolecule metabolic processGO:00106053750.080
Fly
membrane lipid metabolic processGO:0006643670.080
organic anion transportGO:00157111140.077
cellular response to dna damage stimulusGO:00069742870.077
negative regulation of kinase activityGO:0033673240.074
ribonucleoside triphosphate catabolic processGO:00092033270.073
mapk cascadeGO:0000165300.072
membrane lipid biosynthetic processGO:0046467540.072
purine ribonucleoside catabolic processGO:00461303300.070
negative regulation of map kinase activityGO:004340790.069
regulation of cellular component organizationGO:00511283340.069
regulation of protein modification processGO:00313991100.068
Mouse
intracellular signal transductionGO:00355561120.068
negative regulation of cellular macromolecule biosynthetic processGO:20001132890.068
purine ribonucleotide catabolic processGO:00091543270.066
cellular protein complex assemblyGO:00436232090.066
purine nucleoside metabolic processGO:00422783800.065
ribonucleoside catabolic processGO:00424543320.065
protein import into mitochondrial matrixGO:0030150200.065
regulation of phosphate metabolic processGO:00192202300.064
Mouse
negative regulation of protein phosphorylationGO:0001933240.062
protein phosphorylationGO:00064681970.061
Mouse
regulation of kinase activityGO:0043549710.061
Mouse
cellular nitrogen compound catabolic processGO:00442704940.060
protein complex assemblyGO:00064613020.059
positive regulation of phosphorus metabolic processGO:00105621470.059
Mouse
single organism catabolic processGO:00447126190.059
organic cyclic compound catabolic processGO:19013614990.058
negative regulation of transferase activityGO:0051348310.057
regulation of phosphorus metabolic processGO:00511742300.057
Mouse
regulation of transportGO:0051049850.056
establishment of protein localization to mitochondrionGO:0072655630.055
lipid metabolic processGO:00066292690.055
negative regulation of cellular metabolic processGO:00313244070.055
cytoskeleton organizationGO:00070102300.054
Fly
nucleus organizationGO:0006997620.053
Yeast
regulation of signal transductionGO:00099661140.053
Mouse
positive regulation of phosphate metabolic processGO:00459371470.051
Mouse
negative regulation of cellular component organizationGO:00511291090.051
negative regulation of nucleic acid templated transcriptionGO:19035072600.050
meiotic nuclear divisionGO:00071261630.049
nucleoside phosphate catabolic processGO:19012923310.049
gpi anchor metabolic processGO:0006505280.048
ribonucleoside triphosphate metabolic processGO:00091993560.048
cell surface receptor signaling pathwayGO:0007166380.048
Mouse
regulation of response to stressGO:0080134570.048
glycerolipid metabolic processGO:00464861080.048
positive regulation of macromolecule metabolic processGO:00106043940.048
Mouse
aromatic compound catabolic processGO:00194394910.045
single organism developmental processGO:00447672580.045
Human Mouse
negative regulation of protein metabolic processGO:0051248850.044
nucleoside triphosphate catabolic processGO:00091433290.044
negative regulation of mapk cascadeGO:0043409110.044
ribose phosphate metabolic processGO:00196933840.044
regulation of membrane lipid distributionGO:0097035140.043
cotranslational protein targeting to membraneGO:0006613150.043
Yeast
negative regulation of catalytic activityGO:0043086600.042
positive regulation of cell deathGO:001094230.042
spindle organizationGO:0007051370.042
negative regulation of signalingGO:0023057300.041
Mouse
mitotic cell cycle processGO:19030472940.041
cellular protein catabolic processGO:00442572130.041
Yeast Mouse
cellular response to chemical stimulusGO:00708873150.041
Mouse Rat
purine nucleotide metabolic processGO:00061633760.041
localization within membraneGO:0051668290.040
purine ribonucleoside triphosphate metabolic processGO:00092053540.040
negative regulation of nitrogen compound metabolic processGO:00511723000.040
regulation of signalingGO:00230511190.040
Mouse
ribosome biogenesisGO:00422543350.039
cell wall biogenesisGO:0042546930.039
negative regulation of biosynthetic processGO:00098903120.039
protein glycosylationGO:0006486570.038
organophosphate metabolic processGO:00196375970.038
purine nucleoside catabolic processGO:00061523300.038
regulation of protein ubiquitinationGO:0031396200.038
Mouse
ncrna processingGO:00344703300.038
ion transportGO:00068112740.037
cellular response to organic substanceGO:00713101590.037
Mouse
regulation of protein metabolic processGO:00512462370.037
Mouse
nucleoside metabolic processGO:00091163940.036
negative regulation of cellular biosynthetic processGO:00313273120.036
regulation of gene expression epigeneticGO:00400291470.036
Fly
nucleocytoplasmic transportGO:00069131630.035
cellular response to pheromoneGO:0071444880.035
maintenance of location in cellGO:0051651580.035
Human
developmental processGO:00325022610.035
Human Mouse
macromolecular complex disassemblyGO:0032984800.034
karyogamyGO:0000741170.034
Yeast
nucleoside triphosphate metabolic processGO:00091413640.034
negative regulation of rna metabolic processGO:00512532620.033
gtp catabolic processGO:00061841070.033
proteolysisGO:00065082680.033
Yeast Mouse
sporulationGO:00439341320.033
organic hydroxy compound metabolic processGO:19016151250.033
regulation of purine nucleotide metabolic processGO:19005421090.031
purine containing compound catabolic processGO:00725233320.031
ribonucleotide catabolic processGO:00092613270.031
organophosphate catabolic processGO:00464343380.031
phosphatidylinositol biosynthetic processGO:0006661390.031
protein catabolic processGO:00301632210.031
Yeast Mouse
gpi anchor biosynthetic processGO:0006506260.031
nucleoside catabolic processGO:00091643350.030
regulation of cellular protein metabolic processGO:00322682320.030
Mouse
regulation of hydrolase activityGO:00513361330.030
Mouse
nucleobase containing compound catabolic processGO:00346554790.030
negative regulation of macromolecule biosynthetic processGO:00105582910.030
positive regulation of kinase activityGO:0033674240.030
Mouse
intracellular protein transmembrane importGO:0044743670.030
glycosyl compound metabolic processGO:19016573980.030
fungal type cell wall organizationGO:00315051450.030
positive regulation of phosphorylationGO:0042327330.030
Mouse
rrna processingGO:00063642270.030
rrna metabolic processGO:00160722440.029
purine ribonucleotide metabolic processGO:00091503720.029
regulation of protein modification by small protein conjugation or removalGO:1903320290.029
Mouse
purine ribonucleoside triphosphate catabolic processGO:00092073270.029
negative regulation of phosphorus metabolic processGO:0010563490.029
guanosine containing compound catabolic processGO:19010691090.029
protein complex biogenesisGO:00702713140.029
ribonucleoside metabolic processGO:00091193890.028
regulation of organelle organizationGO:00330432430.028
response to temperature stimulusGO:0009266740.028
nuclear exportGO:00511681240.028
negative regulation of protein serine threonine kinase activityGO:0071901180.028
regulation of nucleoside metabolic processGO:00091181060.028
ribonucleoprotein complex subunit organizationGO:00718261520.027
gene silencingGO:00164581510.027
Fly
external encapsulating structure organizationGO:00452291460.027
glycerolipid biosynthetic processGO:0045017710.027
positive regulation of apoptotic processGO:004306530.026
glycerophospholipid metabolic processGO:0006650980.026
alcohol metabolic processGO:00060661120.026
regulation of intracellular signal transductionGO:1902531780.026
guanosine containing compound metabolic processGO:19010681110.025
membrane buddingGO:0006900220.024
response to external stimulusGO:00096051580.024
Human
glycerophospholipid biosynthetic processGO:0046474680.024
carbohydrate derivative transportGO:1901264270.024
negative regulation of rna biosynthetic processGO:19026792600.024
regulation of nucleotide metabolic processGO:00061401100.024
purine nucleotide catabolic processGO:00061953280.023
nucleoside phosphate metabolic processGO:00067534580.023
ribonucleoprotein complex assemblyGO:00226181430.023
purine nucleoside triphosphate catabolic processGO:00091463290.023
negative regulation of phosphate metabolic processGO:0045936490.023
microtubule cytoskeleton organizationGO:00002261090.023
Fly
protein sumoylationGO:0016925170.022
generation of precursor metabolites and energyGO:00060911470.022
glycoprotein metabolic processGO:0009100620.022
g protein coupled receptor signaling pathwayGO:0007186370.022
positive regulation of hydrolase activityGO:00513451120.021
Mouse
response to organic cyclic compoundGO:001407010.021
homeostatic processGO:00425922270.021
endomembrane system organizationGO:0010256740.020
nuclear transportGO:00511691650.020
negative regulation of gene expression epigeneticGO:00458141470.020
purine ribonucleoside metabolic processGO:00461283800.020
positive regulation of protein metabolic processGO:0051247930.020
Mouse
stress activated protein kinase signaling cascadeGO:003109840.020
glycosyl compound catabolic processGO:19016583350.020
proteolysis involved in cellular protein catabolic processGO:00516031980.020
Yeast Mouse
nucleobase containing small molecule metabolic processGO:00550864910.020
detection of stimulusGO:005160640.020
liposaccharide metabolic processGO:1903509310.020
purine nucleoside triphosphate metabolic processGO:00091443560.020
positive regulation of programmed cell deathGO:004306830.019
positive regulation of protein phosphorylationGO:0001934280.019
Mouse
anion transportGO:00068201450.019
rna localizationGO:00064031120.019
response to pheromone involved in conjugation with cellular fusionGO:0000749740.019
agingGO:0007568710.019
sexual sporulationGO:00342931130.019
organelle inheritanceGO:0048308510.019
protein transmembrane transportGO:0071806820.019
apoptotic processGO:0006915300.018
Human
cellular protein complex disassemblyGO:0043624420.018
anatomical structure morphogenesisGO:00096531600.018
Mouse
response to unfolded proteinGO:0006986290.018
regulation of multi organism processGO:0043900200.018
lipoprotein metabolic processGO:0042157400.018
regulation of cellular localizationGO:0060341500.018
phosphorylationGO:00163102910.017
Mouse
negative regulation of transcription dna templatedGO:00458922580.017
chemical homeostasisGO:00488781370.017
gtp metabolic processGO:00460391070.017
cellular response to topologically incorrect proteinGO:0035967320.017
Mouse
cation transmembrane transportGO:00986551350.017
positive regulation of nitrogen compound metabolic processGO:00511734120.017
Mouse
karyogamy involved in conjugation with cellular fusionGO:0000742150.017
Yeast
golgi vesicle transportGO:00481931880.017
lipid transportGO:0006869580.017
regulation of nucleotide catabolic processGO:00308111060.017
phospholipid biosynthetic processGO:0008654890.017
organophosphate ester transportGO:0015748450.017
nucleotide metabolic processGO:00091174530.017
inorganic ion transmembrane transportGO:00986601090.017
ribonucleotide metabolic processGO:00092593770.017
regulation of dna templated transcription in response to stressGO:0043620510.017
regulation of metal ion transportGO:001095920.016
positive regulation of secretion by cellGO:190353220.016
protein lipidationGO:0006497400.016
nucleotide catabolic processGO:00091663300.016
er nucleus signaling pathwayGO:0006984230.016
Mouse
atp metabolic processGO:00460342510.016
cellular cation homeostasisGO:00300031000.016
ribonucleoside monophosphate catabolic processGO:00091582240.016
stress activated mapk cascadeGO:005140340.015
energy derivation by oxidation of organic compoundsGO:00159801250.015
cellular component disassemblyGO:0022411860.015
response to endoplasmic reticulum stressGO:0034976230.015
Mouse Rat
aerobic respirationGO:0009060550.015
regulation of intracellular transportGO:0032386260.014
endoplasmic reticulum unfolded protein responseGO:0030968230.014
Mouse
regulation of chromatin organizationGO:1902275230.014
cellular chemical homeostasisGO:00550821230.014
protein complex disassemblyGO:0043241700.014
negative regulation of phosphorylationGO:0042326280.014
positive regulation of purine nucleotide catabolic processGO:0033123970.014
cellular response to unfolded proteinGO:0034620230.014
Mouse
organelle assemblyGO:00709251180.014
positive regulation of nucleotide metabolic processGO:00459811010.014
positive regulation of nucleobase containing compound metabolic processGO:00459354090.013
Mouse
mitochondrion organizationGO:00070052610.013
purine containing compound metabolic processGO:00725214000.013
establishment of vesicle localizationGO:005165090.013
potassium ion transportGO:0006813170.013
steroid metabolic processGO:0008202470.013
positive regulation of transportGO:0051050320.013
glycoprotein biosynthetic processGO:0009101610.013
programmed cell deathGO:0012501300.013
Human
cellular homeostasisGO:00197251380.013
positive regulation of molecular functionGO:00440931850.013
Mouse
positive regulation of nucleoside metabolic processGO:0045979970.013
positive regulation of intracellular transportGO:003238840.013
positive regulation of protein modification processGO:0031401490.013
Mouse
maintenance of protein location in cellGO:0032507500.012
Human
endoplasmic reticulum organizationGO:0007029300.012
regulation of purine nucleotide catabolic processGO:00331211060.012
posttranslational protein targeting to membraneGO:0006620170.012
signal transduction involved in conjugation with cellular fusionGO:0032005310.012
pheromone dependent signal transduction involved in conjugation with cellular fusionGO:0000750310.012
organonitrogen compound catabolic processGO:19015654040.012
negative regulation of gene expressionGO:00106293120.012
Fly
organophosphate biosynthetic processGO:00904071820.012
chromatin silencingGO:00063421470.012
organic acid metabolic processGO:00060823520.012
response to pheromoneGO:0019236920.012
positive regulation of organelle organizationGO:0010638850.012
protein refoldingGO:0042026160.011
dephosphorylationGO:00163111270.011
nuclear divisionGO:00002802630.011
nucleoside monophosphate catabolic processGO:00091252240.011
fungal type cell wall assemblyGO:0071940530.011
regulation of phosphorylationGO:0042325860.011
Mouse
cell developmentGO:00484681070.011
sphingolipid biosynthetic processGO:0030148290.011
regulation of gtpase activityGO:0043087840.011
meiotic cell cycleGO:00513212720.011
copii coated vesicle buddingGO:0090114120.011
regulation of reproductive processGO:2000241240.011
alpha amino acid metabolic processGO:19016051240.011
response to calcium ionGO:005159210.011
sporulation resulting in formation of a cellular sporeGO:00304351290.011
positive regulation of protein kinase activityGO:0045860220.011
Mouse
mitochondrial transportGO:0006839760.011
protein localization to mitochondrionGO:0070585630.011
rna splicingGO:00083801310.011
response to extracellular stimulusGO:00099911560.011
Human
regulation of establishment of protein localizationGO:0070201170.011
ion homeostasisGO:00508011180.011
regulation of stress activated mapk cascadeGO:003287240.010
positive regulation of cellular component organizationGO:00511301160.010
positive regulation of cytoplasmic transportGO:190365140.010
inorganic cation transmembrane transportGO:0098662980.010
regulation of protein transportGO:0051223170.010
ascospore wall biogenesisGO:0070591520.010
gene silencing by rnaGO:003104730.010
Fly
posttranscriptional regulation of gene expressionGO:00106081150.010
Fly
cellular metabolic compound salvageGO:0043094200.010
cellular ion homeostasisGO:00068731120.010
fungal type cell wall biogenesisGO:0009272800.010

LHS1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.012