Saccharomyces cerevisiae

100 known processes

MEC1 (YBR136W)

Mec1p

(Aliases: SAD3,ESR1)

MEC1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
anatomical structure homeostasisGO:0060249740.987
cellular response to dna damage stimulusGO:00069742870.980
recombinational repairGO:0000725640.976
Fly
dna recombinationGO:00063101720.963
meiotic cell cycle processGO:19030462290.901
meiotic cell cycleGO:00513212720.885
telomere maintenanceGO:0000723740.883
dna repairGO:00062812360.854
Fly
regulation of biological qualityGO:00650083910.854
telomere organizationGO:0032200750.850
meiotic nuclear divisionGO:00071261630.832
meiosis iGO:0007127920.758
homeostatic processGO:00425922270.748
double strand break repairGO:00063021050.691
Fly
telomere maintenance via telomere lengtheningGO:0010833220.688
organelle fissionGO:00482852720.671
telomere maintenance via telomeraseGO:0007004210.632
nuclear divisionGO:00002802630.616
telomere maintenance via recombinationGO:0000722320.601
dna damage checkpointGO:0000077290.589
Human Fly
double strand break repair via homologous recombinationGO:0000724540.559
Fly
dna replicationGO:00062601470.555
macromolecule catabolic processGO:00090573830.513
Fly
regulation of dna metabolic processGO:00510521000.511
nucleic acid phosphodiester bond hydrolysisGO:00903051940.487
Fly
dna dependent dna replicationGO:00062611150.481
nucleotide excision repairGO:0006289500.418
reproduction of a single celled organismGO:00325051910.414
signal transductionGO:00071652080.410
Human
dna geometric changeGO:0032392430.369
heterocycle catabolic processGO:00467004940.360
Fly
developmental process involved in reproductionGO:00030061590.355
cellular macromolecule catabolic processGO:00442653630.346
Fly
cellular nitrogen compound catabolic processGO:00442704940.345
Fly
response to chemicalGO:00422213900.309
Fly
single organism reproductive processGO:00447021590.305
negative regulation of cell cycle processGO:0010948860.303
Fly
nucleobase containing compound catabolic processGO:00346554790.296
Fly
negative regulation of cell cycle phase transitionGO:1901988590.283
Fly
negative regulation of dna metabolic processGO:0051053360.279
Human
single organism signalingGO:00447002080.272
Human
cell communicationGO:00071543450.271
Human
cell cycle checkpointGO:0000075820.270
Human Fly
dna duplex unwindingGO:0032508420.252
single organism catabolic processGO:00447126190.228
Fly
organic cyclic compound catabolic processGO:19013614990.226
Fly
sex determinationGO:0007530320.224
regulation of cell cycle processGO:00105641500.216
Fly
dna integrity checkpointGO:0031570410.211
Human Fly
negative regulation of cell divisionGO:0051782660.209
cell fate commitmentGO:0045165320.205
developmental processGO:00325022610.200
Human Fly
mitotic recombinationGO:0006312550.199
negative regulation of cellular metabolic processGO:00313244070.197
Human
protein phosphorylationGO:00064681970.193
aromatic compound catabolic processGO:00194394910.193
Fly
dna unwinding involved in dna replicationGO:0006268130.189
establishment of protein localizationGO:00451843670.189
cell differentiationGO:00301541610.188
response to oxygen containing compoundGO:1901700610.188
carbohydrate derivative metabolic processGO:19011355490.185
negative regulation of nucleobase containing compound metabolic processGO:00459342950.162
Human
regulation of cellular protein metabolic processGO:00322682320.160
reproductive processGO:00224142480.158
organophosphate metabolic processGO:00196375970.158
reproductive process in single celled organismGO:00224131450.158
single organism developmental processGO:00447672580.154
Human Fly
fungal type cell wall organization or biogenesisGO:00718521690.154
protein modification by small protein conjugationGO:00324461440.152
regulation of response to stimulusGO:00485831570.146
Human
cell wall organization or biogenesisGO:00715541900.141
response to extracellular stimulusGO:00099911560.131
mating type switchingGO:0007533280.129
protein modification by small protein conjugation or removalGO:00706471720.123
regulation of protein modification processGO:00313991100.120
negative regulation of mitotic cell cycleGO:0045930630.118
Fly
regulation of meiotic cell cycleGO:0051445430.114
lipid metabolic processGO:00066292690.109
mismatch repairGO:0006298140.108
cellular component morphogenesisGO:0032989970.104
Fly
signalingGO:00230522080.104
Human
regulation of cell cycle phase transitionGO:1901987700.103
Fly
regulation of meiosisGO:0040020420.101
agingGO:0007568710.101
Human
phosphorylationGO:00163102910.099
regulation of signalingGO:00230511190.097
Human
cell growthGO:0016049890.095
nucleoside triphosphate metabolic processGO:00091413640.093
protein ubiquitinationGO:00165671180.092
asexual reproductionGO:0019954480.091
positive regulation of cellular protein metabolic processGO:0032270890.088
negative regulation of cellular biosynthetic processGO:00313273120.088
Human
regulation of dna replicationGO:0006275510.086
positive regulation of phosphorus metabolic processGO:00105621470.085
cellular developmental processGO:00488691910.084
Fly
chromatin organizationGO:00063252420.084
dna topological changeGO:0006265100.083
rna dependent dna replicationGO:0006278250.082
positive regulation of protein modification processGO:0031401490.082
nuclear transportGO:00511691650.082
dna catabolic processGO:0006308420.082
Fly
histone modificationGO:00165701190.082
double strand break repair via break induced replicationGO:0000727250.080
double strand break repair via synthesis dependent strand annealingGO:0045003120.079
Fly
regulation of cell cycleGO:00517261950.079
Fly
cellular protein catabolic processGO:00442572130.078
regulation of cell divisionGO:00513021130.074
Fly
positive regulation of phosphate metabolic processGO:00459371470.074
cell buddingGO:0007114480.073
negative regulation of nuclear divisionGO:0051784620.071
growthGO:00400071570.070
maintenance of protein location in cellGO:0032507500.069
regulation of transportGO:0051049850.069
cell cycle phase transitionGO:00447701440.069
Fly
regulation of cellular component organizationGO:00511283340.069
Fly
intracellular protein transportGO:00068863190.068
negative regulation of cellular component organizationGO:00511291090.067
reciprocal meiotic recombinationGO:0007131540.065
mitotic cell cycle checkpointGO:0007093560.063
Fly
double strand break repair via single strand annealingGO:004500270.063
Fly
negative regulation of cell communicationGO:0010648330.062
negative regulation of mitotic cell cycle phase transitionGO:1901991570.061
Fly
purine containing compound catabolic processGO:00725233320.060
positive regulation of gene expressionGO:00106283210.059
alcohol metabolic processGO:00060661120.059
reciprocal dna recombinationGO:0035825540.058
response to nutrient levelsGO:00316671500.058
regulation of molecular functionGO:00650093200.057
positive regulation of cellular component organizationGO:00511301160.056
filamentous growthGO:00304471240.056
positive regulation of endocytosisGO:0045807120.056
positive regulation of transportGO:0051050320.056
nucleobase containing small molecule metabolic processGO:00550864910.056
rna catabolic processGO:00064011180.054
anion transportGO:00068201450.054
cellular response to external stimulusGO:00714961500.053
monosaccharide transportGO:0015749240.051
response to organic substanceGO:00100331820.050
Fly
glucose metabolic processGO:0006006650.050
nucleocytoplasmic transportGO:00069131630.050
cellular lipid metabolic processGO:00442552290.050
translationGO:00064122300.049
ribonucleoside monophosphate metabolic processGO:00091612650.049
heteroduplex formationGO:003049190.048
regulation of dna repairGO:0006282140.048
purine ribonucleoside monophosphate metabolic processGO:00091672620.048
organic hydroxy compound metabolic processGO:19016151250.047
regulation of cellular component biogenesisGO:00440871120.046
chromosome localizationGO:0050000200.045
nucleoside phosphate metabolic processGO:00067534580.045
mating type determinationGO:0007531320.045
monocarboxylic acid metabolic processGO:00327871220.044
cellular homeostasisGO:00197251380.044
organonitrogen compound biosynthetic processGO:19015663140.043
regulation of mitotic cell cycle phase transitionGO:1901990680.043
Fly
negative regulation of meiotic cell cycleGO:0051447240.043
regulation of signal transductionGO:00099661140.042
Human
cell agingGO:0007569700.042
Human
purine nucleoside metabolic processGO:00422783800.042
negative regulation of nitrogen compound metabolic processGO:00511723000.042
Human
nucleoside monophosphate metabolic processGO:00091232670.041
oxoacid metabolic processGO:00434363510.041
maintenance of locationGO:0051235660.041
regulation of mitotic cell cycleGO:00073461070.041
Fly
ion transportGO:00068112740.040
purine nucleoside monophosphate metabolic processGO:00091262620.040
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145350.040
response to abiotic stimulusGO:00096281590.040
Human
dna strand elongationGO:0022616290.039
regulation of gene silencingGO:0060968410.039
protein transportGO:00150313450.039
cellular amino acid metabolic processGO:00065202250.039
meiotic mismatch repairGO:000071090.039
fungal type cell wall organizationGO:00315051450.038
cell divisionGO:00513012050.038
Fly
ubiquitin dependent protein catabolic processGO:00065111810.038
intracellular signal transductionGO:00355561120.038
Human
ribonucleoside metabolic processGO:00091193890.038
purine nucleotide metabolic processGO:00061633760.038
negative regulation of cellular protein metabolic processGO:0032269850.037
purine ribonucleotide metabolic processGO:00091503720.037
regulation of catalytic activityGO:00507903070.037
dna dependent dna replication maintenance of fidelityGO:0045005140.037
nuclear exportGO:00511681240.037
chemical homeostasisGO:00488781370.036
regulation of response to dna damage stimulusGO:2001020170.036
Human
nucleoside metabolic processGO:00091163940.036
positive regulation of nucleobase containing compound metabolic processGO:00459354090.035
anatomical structure developmentGO:00488561600.035
Fly
base excision repairGO:0006284140.035
cellular response to nutrient levelsGO:00316691440.035
spindle assembly checkpointGO:0071173230.034
protein catabolic processGO:00301632210.034
regulation of localizationGO:00328791270.034
ribonucleotide metabolic processGO:00092593770.034
positive regulation of protein metabolic processGO:0051247930.034
organelle assemblyGO:00709251180.034
non recombinational repairGO:0000726330.033
Fly
purine ribonucleoside metabolic processGO:00461283800.033
covalent chromatin modificationGO:00165691190.033
organic acid metabolic processGO:00060823520.033
proteolysis involved in cellular protein catabolic processGO:00516031980.033
cellular chemical homeostasisGO:00550821230.033
cellular response to oxidative stressGO:0034599940.033
external encapsulating structure organizationGO:00452291460.033
atp metabolic processGO:00460342510.033
posttranscriptional regulation of gene expressionGO:00106081150.032
positive regulation of phosphorylationGO:0042327330.032
carbohydrate metabolic processGO:00059752520.032
negative regulation of phosphorylationGO:0042326280.031
cellular response to chemical stimulusGO:00708873150.031
negative regulation of macromolecule biosynthetic processGO:00105582910.030
Human
response to starvationGO:0042594960.030
osmosensory signaling pathwayGO:0007231220.030
lipid localizationGO:0010876600.029
regulation of phosphate metabolic processGO:00192202300.029
regulation of translationGO:0006417890.029
negative regulation of signalingGO:0023057300.029
mitochondrion organizationGO:00070052610.029
negative regulation of response to stimulusGO:0048585400.029
protein complex assemblyGO:00064613020.029
organophosphate biosynthetic processGO:00904071820.028
glycerophospholipid metabolic processGO:0006650980.028
nucleotide metabolic processGO:00091174530.028
ribose phosphate metabolic processGO:00196933840.028
nucleoside catabolic processGO:00091643350.027
regulation of cell communicationGO:00106461240.027
Human
positive regulation of intracellular protein transportGO:009031630.027
mitotic cell cycle phase transitionGO:00447721410.027
Fly
protein dna complex subunit organizationGO:00718241530.027
positive regulation of biosynthetic processGO:00098913360.026
negative regulation of organelle organizationGO:00106391030.026
organonitrogen compound catabolic processGO:19015654040.026
response to oxidative stressGO:0006979990.026
regulation of protein serine threonine kinase activityGO:0071900410.026
ribonucleoside catabolic processGO:00424543320.025
positive regulation of macromolecule metabolic processGO:00106043940.025
programmed cell deathGO:0012501300.025
negative regulation of signal transductionGO:0009968300.025
glycosyl compound catabolic processGO:19016583350.025
microtubule cytoskeleton organizationGO:00002261090.025
positive regulation of intracellular transportGO:003238840.025
gene conversion at mating type locusGO:0007534110.025
regulation of anatomical structure sizeGO:0090066500.024
carboxylic acid biosynthetic processGO:00463941520.024
response to osmotic stressGO:0006970830.024
negative regulation of cellular macromolecule biosynthetic processGO:20001132890.024
Human
positive regulation of cellular biosynthetic processGO:00313283360.024
nucleoside triphosphate catabolic processGO:00091433290.024
sexual reproductionGO:00199532160.023
regulation of response to stressGO:0080134570.023
Human
purine nucleoside catabolic processGO:00061523300.023
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435240.023
purine containing compound metabolic processGO:00725214000.023
regulation of cellular catabolic processGO:00313291950.023
purine nucleoside monophosphate catabolic processGO:00091282240.023
telomere cappingGO:0016233100.023
filamentous growth of a population of unicellular organismsGO:00441821090.023
negative regulation of dna replicationGO:0008156150.022
Human
dna catabolic process exonucleolyticGO:0000738190.022
Fly
positive regulation of molecular functionGO:00440931850.022
protein maturationGO:0051604760.022
negative regulation of intracellular signal transductionGO:1902532270.022
microtubule based processGO:00070171170.022
nucleoside phosphate catabolic processGO:19012923310.022
nucleotide catabolic processGO:00091663300.021
response to drugGO:0042493410.021
mitotic cell cycle processGO:19030472940.021
Fly
atp catabolic processGO:00062002240.021
negative regulation of protein catabolic processGO:0042177270.021
organophosphate catabolic processGO:00464343380.021
modification dependent macromolecule catabolic processGO:00436322030.021
ribonucleotide catabolic processGO:00092613270.021
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051270.021
negative regulation of cell cycleGO:0045786910.021
Fly
negative regulation of mitosisGO:0045839390.021
organic hydroxy compound biosynthetic processGO:1901617810.021
dna conformation changeGO:0071103980.021
Fly
positive regulation of macromolecule biosynthetic processGO:00105573250.021
purine ribonucleoside monophosphate catabolic processGO:00091692240.021
purine ribonucleoside catabolic processGO:00461303300.020
negative regulation of gene silencingGO:0060969270.020
purine ribonucleoside triphosphate metabolic processGO:00092053540.020
ribonucleoside triphosphate metabolic processGO:00091993560.020
cell morphogenesisGO:0000902300.020
Fly
purine ribonucleoside triphosphate catabolic processGO:00092073270.019
cellular glucan metabolic processGO:0006073440.019
regulation of intracellular signal transductionGO:1902531780.019
Human
ribonucleoside monophosphate catabolic processGO:00091582240.019
multi organism reproductive processGO:00447032160.019
purine nucleoside triphosphate metabolic processGO:00091443560.018
purine nucleotide catabolic processGO:00061953280.018
purine ribonucleotide catabolic processGO:00091543270.018
regulation of phosphorylationGO:0042325860.018
cellular response to extracellular stimulusGO:00316681500.018
regulation of protein metabolic processGO:00512462370.018
cellular carbohydrate metabolic processGO:00442621350.018
purine nucleoside triphosphate catabolic processGO:00091463290.017
cell developmentGO:00484681070.017
regulation of dna recombinationGO:0000018240.017
actin filament based processGO:00300291040.017
Fly
response to uvGO:000941140.017
Human
replicative cell agingGO:0001302460.017
nucleoside monophosphate catabolic processGO:00091252240.017
regulation of organelle organizationGO:00330432430.017
Fly
ribonucleoside triphosphate catabolic processGO:00092033270.017
spindle checkpointGO:0031577350.017
anatomical structure morphogenesisGO:00096531600.017
Fly
regulation of endocytosisGO:0030100170.017
alcohol biosynthetic processGO:0046165750.017
transmembrane transportGO:00550853490.017
glycosyl compound metabolic processGO:19016573980.017
response to organic cyclic compoundGO:001407010.016
Fly
dna biosynthetic processGO:0071897330.016
negative regulation of macromolecule metabolic processGO:00106053750.016
Human
modification dependent protein catabolic processGO:00199411810.016
rrna metabolic processGO:00160722440.016
carbohydrate derivative catabolic processGO:19011363390.016
positive regulation of cytoplasmic transportGO:190365140.016
pseudohyphal growthGO:0007124750.016
regulation of cytoskeleton organizationGO:0051493630.016
maintenance of protein locationGO:0045185530.015
lipid transportGO:0006869580.015
chromatin assembly or disassemblyGO:0006333600.015
lipid biosynthetic processGO:00086101700.015
negative regulation of phosphate metabolic processGO:0045936490.015
regulation of protein phosphorylationGO:0001932750.015
cellular protein complex assemblyGO:00436232090.015
ion homeostasisGO:00508011180.015
regulation of chromosome organizationGO:0033044660.015
cellular response to organic substanceGO:00713101590.014
cell cycle g1 s phase transitionGO:0044843640.014
membrane lipid biosynthetic processGO:0046467540.014
regulation of protein kinase activityGO:0045859670.014
meiotic chromosome segregationGO:0045132310.014
Fly
growth of unicellular organism as a thread of attached cellsGO:00707831050.014
single organism carbohydrate metabolic processGO:00447232370.014
gene conversionGO:0035822140.014
protein processingGO:0016485640.014
positive regulation of programmed cell deathGO:004306830.014
regulation of dna dependent dna replicationGO:0090329370.014
regulation of lipid metabolic processGO:0019216450.014
response to external stimulusGO:00096051580.014
mitotic spindle checkpointGO:0071174340.014
membrane organizationGO:00610242760.014
cellular response to abiotic stimulusGO:0071214620.014
Human
positive regulation of nitrogen compound metabolic processGO:00511734120.014
meiotic dna double strand break processingGO:000070650.013
Fly
positive regulation of nucleocytoplasmic transportGO:004682440.013
regulation of nuclear divisionGO:00517831030.013
Fly
mitotic dna damage checkpointGO:0044773110.013
Fly
regulation of transferase activityGO:0051338830.013
organelle localizationGO:00516401280.013
positive regulation of catalytic activityGO:00430851780.013
dna double strand break processingGO:000072980.013
Fly
small molecule biosynthetic processGO:00442832580.013
positive regulation of catabolic processGO:00098961350.013
positive regulation of rna metabolic processGO:00512542940.013
maintenance of location in cellGO:0051651580.013
mrna metabolic processGO:00160712690.013
protein localization to organelleGO:00333653370.013
positive regulation of cell deathGO:001094230.013
spore wall biogenesisGO:0070590520.013
protein complex localizationGO:0031503320.013
regulation of protein processingGO:0070613340.012
negative regulation of protein processingGO:0010955330.012
cellular response to osmotic stressGO:0071470500.012
mitotic dna integrity checkpointGO:0044774180.012
Fly
response to inorganic substanceGO:0010035470.012
lagging strand elongationGO:0006273100.012
cellular amine metabolic processGO:0044106510.012
nucleoside phosphate biosynthetic processGO:1901293800.012
cell deathGO:0008219300.012
negative regulation of phosphorus metabolic processGO:0010563490.012
endocytosisGO:0006897900.012
negative regulation of protein modification processGO:0031400370.012
glycogen metabolic processGO:0005977300.012
negative regulation of dna dependent dna replicationGO:200010480.012
phospholipid metabolic processGO:00066441250.012
regulation of dna templated transcription in response to stressGO:0043620510.012
microtubule anchoringGO:0034453250.012
polyol metabolic processGO:0019751220.011
carbohydrate derivative biosynthetic processGO:19011371810.011
positive regulation of cell cycle processGO:0090068310.011
regulation of translational elongationGO:0006448250.011
apoptotic processGO:0006915300.011
regulation of protein modification by small protein conjugation or removalGO:1903320290.011
single organism membrane fusionGO:0044801710.011
proteolysisGO:00065082680.011
regulation of hydrolase activityGO:00513361330.011
positive regulation of protein kinase activityGO:0045860220.011
positive regulation of response to stimulusGO:0048584370.011
Human
cellular ketone metabolic processGO:0042180630.011
cell cycle dna replicationGO:0044786360.011
positive regulation of secretionGO:005104720.011
positive regulation of protein phosphorylationGO:0001934280.011
regulation of homeostatic processGO:0032844190.010
cation homeostasisGO:00550801050.010
rna localizationGO:00064031120.010
transposition rna mediatedGO:0032197170.010
membrane lipid metabolic processGO:0006643670.010
response to nitrogen compoundGO:1901698180.010
Fly
establishment of rna localizationGO:0051236920.010
regulation of phosphorus metabolic processGO:00511742300.010

MEC1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.013
disease of cellular proliferationDOID:1456600.011
organ system cancerDOID:005068600.010
cancerDOID:16200.010