Saccharomyces cerevisiae

121 known processes

MCM4 (YPR019W)

Mcm4p

(Aliases: CDC54,HCD21)

MCM4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna replicationGO:00062601470.998
recombinational repairGO:0000725640.998
double strand break repair via break induced replicationGO:0000727250.996
dna replication initiationGO:0006270480.996
dna dependent dna replicationGO:00062611150.994
dna recombinationGO:00063101720.992
double strand break repair via homologous recombinationGO:0000724540.974
cellular response to dna damage stimulusGO:00069742870.963
double strand break repairGO:00063021050.949
dna strand elongation involved in dna replicationGO:0006271260.927
dna duplex unwindingGO:0032508420.924
cell cycle dna replicationGO:0044786360.910
dna geometric changeGO:0032392430.900
dna repairGO:00062812360.889
dna unwinding involved in dna replicationGO:0006268130.806
protein dna complex assemblyGO:00650041050.739
regulation of dna dependent dna replication initiationGO:0030174210.730
pre replicative complex assemblyGO:0036388200.719
dna strand elongationGO:0022616290.597
protein dna complex subunit organizationGO:00718241530.586
nuclear dna replicationGO:0033260270.585
pre replicative complex assembly involved in nuclear cell cycle dna replicationGO:0006267200.573
pre replicative complex assembly involved in cell cycle dna replicationGO:1902299200.561
mitotic cell cycle processGO:19030472940.540
Fly
dna conformation changeGO:0071103980.530
single organism signalingGO:00447002080.525
signalingGO:00230522080.408
regulation of cell cycleGO:00517261950.366
negative regulation of mitotic cell cycle phase transitionGO:1901991570.318
cell differentiationGO:00301541610.314
single organism developmental processGO:00447672580.299
meiotic cell cycleGO:00513212720.280
mitotic cell cycleGO:00002783060.277
Fly
purine containing compound metabolic processGO:00725214000.274
cell communicationGO:00071543450.255
regulation of cell cycle processGO:00105641500.247
single organism catabolic processGO:00447126190.216
developmental processGO:00325022610.212
cell cycle phase transitionGO:00447701440.209
meiotic cell cycle processGO:19030462290.193
nuclear divisionGO:00002802630.185
regulation of dna metabolic processGO:00510521000.183
negative regulation of cellular metabolic processGO:00313244070.181
mitotic cell cycle phase transitionGO:00447721410.172
organelle fissionGO:00482852720.167
purine nucleoside metabolic processGO:00422783800.165
negative regulation of cellular macromolecule biosynthetic processGO:20001132890.164
negative regulation of cell divisionGO:0051782660.163
heterocycle catabolic processGO:00467004940.150
negative regulation of cell cycle phase transitionGO:1901988590.146
cellular nitrogen compound catabolic processGO:00442704940.146
carbohydrate derivative metabolic processGO:19011355490.144
negative regulation of cell cycleGO:0045786910.141
oxoacid metabolic processGO:00434363510.139
regulation of phosphorylationGO:0042325860.139
purine ribonucleotide metabolic processGO:00091503720.138
cellular developmental processGO:00488691910.138
ribonucleoside metabolic processGO:00091193890.136
glycosyl compound metabolic processGO:19016573980.135
purine ribonucleoside triphosphate metabolic processGO:00092053540.133
nucleobase containing small molecule metabolic processGO:00550864910.130
negative regulation of cell cycle processGO:0010948860.126
protein complex assemblyGO:00064613020.124
regulation of mitotic cell cycleGO:00073461070.123
chromatin silencing at telomereGO:0006348840.122
reciprocal dna recombinationGO:0035825540.116
nucleoside phosphate metabolic processGO:00067534580.110
negative regulation of transcription dna templatedGO:00458922580.110
ribonucleoside triphosphate metabolic processGO:00091993560.110
negative regulation of mitotic cell cycleGO:0045930630.109
organic acid metabolic processGO:00060823520.109
purine nucleotide metabolic processGO:00061633760.107
dna integrity checkpointGO:0031570410.107
negative regulation of nucleobase containing compound metabolic processGO:00459342950.107
regulation of cellular component organizationGO:00511283340.106
phosphorylationGO:00163102910.106
ribonucleotide metabolic processGO:00092593770.102
regulation of biological qualityGO:00650083910.101
chromosome condensationGO:0030261190.101
gene silencingGO:00164581510.100
cell cycle checkpointGO:0000075820.096
negative regulation of biosynthetic processGO:00098903120.096
multi organism reproductive processGO:00447032160.095
nucleoside catabolic processGO:00091643350.090
glycosyl compound catabolic processGO:19016583350.089
dna damage checkpointGO:0000077290.089
negative regulation of nitrogen compound metabolic processGO:00511723000.086
ribonucleoside monophosphate metabolic processGO:00091612650.083
regulation of mitotic cell cycle phase transitionGO:1901990680.081
mitotic dna integrity checkpointGO:0044774180.080
nucleobase containing compound catabolic processGO:00346554790.078
response to chemicalGO:00422213900.078
regulation of phosphorus metabolic processGO:00511742300.076
regulation of dna replicationGO:0006275510.076
organic cyclic compound catabolic processGO:19013614990.076
negative regulation of cellular component organizationGO:00511291090.076
aromatic compound catabolic processGO:00194394910.075
purine nucleoside catabolic processGO:00061523300.074
regulation of phosphate metabolic processGO:00192202300.074
regulation of cellular component biogenesisGO:00440871120.073
nucleotide metabolic processGO:00091174530.072
positive regulation of cellular component organizationGO:00511301160.071
positive regulation of nitrogen compound metabolic processGO:00511734120.070
cellular amino acid metabolic processGO:00065202250.070
negative regulation of nucleic acid templated transcriptionGO:19035072600.069
positive regulation of nucleobase containing compound metabolic processGO:00459354090.066
negative regulation of dna metabolic processGO:0051053360.066
negative regulation of macromolecule metabolic processGO:00106053750.066
carboxylic acid metabolic processGO:00197523380.066
purine ribonucleoside monophosphate metabolic processGO:00091672620.066
negative regulation of macromolecule biosynthetic processGO:00105582910.065
purine nucleoside triphosphate metabolic processGO:00091443560.063
homeostatic processGO:00425922270.062
reproductive processGO:00224142480.062
positive regulation of macromolecule metabolic processGO:00106043940.062
response to organic substanceGO:00100331820.062
signal transductionGO:00071652080.062
regulation of chromatin silencing at telomereGO:0031938270.061
regulation of molecular functionGO:00650093200.061
nucleoside metabolic processGO:00091163940.059
protein complex biogenesisGO:00702713140.059
nucleoside triphosphate catabolic processGO:00091433290.058
positive regulation of rna metabolic processGO:00512542940.057
regulation of dna dependent dna replicationGO:0090329370.057
ribonucleoside triphosphate catabolic processGO:00092033270.057
g1 s transition of mitotic cell cycleGO:0000082640.057
organonitrogen compound catabolic processGO:19015654040.055
nucleotide catabolic processGO:00091663300.054
negative regulation of gene expression epigeneticGO:00458141470.053
cellular response to chemical stimulusGO:00708873150.053
reciprocal meiotic recombinationGO:0007131540.053
atp metabolic processGO:00460342510.052
purine ribonucleoside metabolic processGO:00461283800.050
regulation of protein complex assemblyGO:0043254770.048
purine nucleotide catabolic processGO:00061953280.048
chromatin assemblyGO:0031497350.047
protein phosphorylationGO:00064681970.046
positive regulation of protein phosphorylationGO:0001934280.046
chromosome segregationGO:00070591590.046
positive regulation of biosynthetic processGO:00098913360.046
positive regulation of nucleic acid templated transcriptionGO:19035082860.045
mitotic nuclear divisionGO:00070671310.045
chromatin silencing at silent mating type cassetteGO:0030466530.044
regulation of gene silencingGO:0060968410.044
multi organism processGO:00517042330.043
purine nucleoside monophosphate metabolic processGO:00091262620.043
purine ribonucleotide catabolic processGO:00091543270.043
negative regulation of cellular biosynthetic processGO:00313273120.043
regulation of signalingGO:00230511190.042
chromatin assembly or disassemblyGO:0006333600.042
ribonucleoside catabolic processGO:00424543320.042
negative regulation of rna biosynthetic processGO:19026792600.041
nucleoside monophosphate metabolic processGO:00091232670.041
sexual reproductionGO:00199532160.040
organophosphate catabolic processGO:00464343380.040
regulation of gene expression epigeneticGO:00400291470.040
cellular response to organic substanceGO:00713101590.039
dna packagingGO:0006323550.039
small molecule biosynthetic processGO:00442832580.039
negative regulation of rna metabolic processGO:00512532620.039
carbohydrate derivative catabolic processGO:19011363390.038
negative regulation of cellular catabolic processGO:0031330430.037
cellular amino acid biosynthetic processGO:00086521180.036
negative regulation of chromatin silencing at telomereGO:0031939150.036
regulation of purine nucleotide metabolic processGO:19005421090.035
positive regulation of cell cycle processGO:0090068310.035
regulation of nucleotide catabolic processGO:00308111060.035
nucleoside monophosphate catabolic processGO:00091252240.035
reproduction of a single celled organismGO:00325051910.034
regulation of catalytic activityGO:00507903070.034
positive regulation of cellular component biogenesisGO:0044089450.033
regulation of cell cycle phase transitionGO:1901987700.033
nitrogen compound transportGO:00717052120.033
macromolecule catabolic processGO:00090573830.032
intracellular signal transductionGO:00355561120.032
atp catabolic processGO:00062002240.032
meiotic nuclear divisionGO:00071261630.031
nucleoside phosphate catabolic processGO:19012923310.030
cation transportGO:00068121660.029
chemical homeostasisGO:00488781370.029
regulation of signal transductionGO:00099661140.029
negative regulation of gene expressionGO:00106293120.029
organonitrogen compound biosynthetic processGO:19015663140.028
regulation of intracellular signal transductionGO:1902531780.028
ribose phosphate metabolic processGO:00196933840.028
regulation of hydrolase activityGO:00513361330.028
cation homeostasisGO:00550801050.028
purine ribonucleoside monophosphate catabolic processGO:00091692240.027
regulation of transcription from rna polymerase ii promoterGO:00063573940.027
negative regulation of catabolic processGO:0009895430.026
positive regulation of phosphate metabolic processGO:00459371470.026
cellular chemical homeostasisGO:00550821230.026
regulation of nucleotide metabolic processGO:00061401100.026
organic acid biosynthetic processGO:00160531520.025
regulation of exit from mitosisGO:0007096290.025
establishment or maintenance of cell polarityGO:0007163960.025
organophosphate metabolic processGO:00196375970.025
negative regulation of organelle organizationGO:00106391030.024
peptidyl amino acid modificationGO:00181931160.024
chromatin organizationGO:00063252420.024
intracellular protein transportGO:00068863190.024
proteolysis involved in cellular protein catabolic processGO:00516031980.024
meiotic chromosome segregationGO:0045132310.024
dna dependent dna replication maintenance of fidelityGO:0045005140.024
positive regulation of macromolecule biosynthetic processGO:00105573250.024
cell cycle g1 s phase transitionGO:0044843640.023
regulation of kinase activityGO:0043549710.023
establishment of organelle localizationGO:0051656960.022
alpha amino acid metabolic processGO:19016051240.022
regulation of meiosis iGO:0060631140.022
negative regulation of molecular functionGO:0044092680.022
negative regulation of nuclear divisionGO:0051784620.022
regulation of cell communicationGO:00106461240.022
carbohydrate metabolic processGO:00059752520.022
lagging strand elongationGO:0006273100.021
positive regulation of cell cycleGO:0045787320.021
regulation of cellular catabolic processGO:00313291950.021
purine containing compound catabolic processGO:00725233320.021
cellular response to starvationGO:0009267900.021
purine ribonucleoside triphosphate catabolic processGO:00092073270.021
positive regulation of gene expressionGO:00106283210.021
negative regulation of dna replicationGO:0008156150.021
actin filament bundle organizationGO:0061572190.020
mitotic cell cycle checkpointGO:0007093560.020
positive regulation of catalytic activityGO:00430851780.020
regulation of catabolic processGO:00098941990.020
cellular homeostasisGO:00197251380.020
nucleobase containing compound transportGO:00159311240.020
dna templated transcription initiationGO:0006352710.020
positive regulation of transcription dna templatedGO:00458932860.020
negative regulation of cellular protein metabolic processGO:0032269850.019
carboxylic acid biosynthetic processGO:00463941520.019
regulation of response to stimulusGO:00485831570.019
response to starvationGO:0042594960.019
positive regulation of protein kinase activityGO:0045860220.019
positive regulation of kinase activityGO:0033674240.019
positive regulation of phosphorus metabolic processGO:00105621470.018
positive regulation of protein modification processGO:0031401490.018
apoptotic processGO:0006915300.018
regulation of response to stressGO:0080134570.018
modification dependent macromolecule catabolic processGO:00436322030.018
negative regulation of dna dependent dna replicationGO:200010480.018
negative regulation of phosphate metabolic processGO:0045936490.018
ribonucleotide catabolic processGO:00092613270.018
detection of stimulusGO:005160640.017
cell cycle g2 m phase transitionGO:0044839390.017
regulation of protein kinase activityGO:0045859670.017
chromatin silencingGO:00063421470.017
cellular response to abiotic stimulusGO:0071214620.017
cellular cation homeostasisGO:00300031000.017
positive regulation of transcription from rna polymerase ii promoterGO:00459442520.017
response to abiotic stimulusGO:00096281590.017
response to oxygen containing compoundGO:1901700610.016
positive regulation of intracellular protein transportGO:009031630.016
positive regulation of molecular functionGO:00440931850.016
mitotic dna damage checkpointGO:0044773110.016
anatomical structure developmentGO:00488561600.016
transmembrane transportGO:00550853490.016
cellular response to external stimulusGO:00714961500.016
cellular ion homeostasisGO:00068731120.015
response to heatGO:0009408690.015
purine nucleoside triphosphate catabolic processGO:00091463290.015
transition metal ion homeostasisGO:0055076590.015
multi organism cellular processGO:00447641200.015
macroautophagyGO:0016236550.015
regulation of organelle organizationGO:00330432430.015
establishment of rna localizationGO:0051236920.014
retrograde transport endosome to golgiGO:0042147330.014
meiosis iGO:0007127920.014
positive regulation of programmed cell deathGO:004306830.014
establishment of protein localizationGO:00451843670.014
purine ribonucleoside catabolic processGO:00461303300.014
ion homeostasisGO:00508011180.014
positive regulation of apoptotic processGO:004306530.014
cell deathGO:0008219300.014
ncrna processingGO:00344703300.014
g2 dna damage checkpointGO:003157210.014
regulation of g2 m transition of mitotic cell cycleGO:001038980.014
cellular response to nutrient levelsGO:00316691440.014
anion transportGO:00068201450.014
response to inorganic substanceGO:0010035470.014
amine metabolic processGO:0009308510.013
non recombinational repairGO:0000726330.013
positive regulation of mitotic cell cycleGO:0045931160.013
single organism cellular localizationGO:19025803750.013
deathGO:0016265300.013
protein ubiquitinationGO:00165671180.013
regulation of protein metabolic processGO:00512462370.013
cell agingGO:0007569700.013
positive regulation of cellular catabolic processGO:00313311280.013
regulation of protein phosphorylationGO:0001932750.013
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:00003771090.013
negative regulation of mitosisGO:0045839390.013
positive regulation of intracellular transportGO:003238840.012
nucleic acid phosphodiester bond hydrolysisGO:00903051940.012
response to extracellular stimulusGO:00099911560.012
g2 m transition of mitotic cell cycleGO:0000086380.012
positive regulation of cell deathGO:001094230.012
conjugation with cellular fusionGO:00007471060.012
growth of unicellular organism as a thread of attached cellsGO:00707831050.012
agingGO:0007568710.012
regulation of cellular amino acid metabolic processGO:0006521160.012
negative regulation of phosphorus metabolic processGO:0010563490.012
positive regulation of transferase activityGO:0051347280.012
positive regulation of organelle organizationGO:0010638850.012
dna templated transcriptional preinitiation complex assemblyGO:0070897510.012
proteasome mediated ubiquitin dependent protein catabolic processGO:00431611370.012
cellular ketone metabolic processGO:0042180630.012
metal ion homeostasisGO:0055065790.012
negative regulation of exit from mitosisGO:0001100160.012
chromatin modificationGO:00165682000.012
programmed cell deathGO:0012501300.011
regulation of dna templated transcription initiationGO:2000142190.011
cellular amine metabolic processGO:0044106510.011
positive regulation of rna biosynthetic processGO:19026802860.011
positive regulation of cellular biosynthetic processGO:00313283360.011
regulation of protein modification processGO:00313991100.011
regulation of chromatin silencingGO:0031935390.011
cell divisionGO:00513012050.011
cellular metal ion homeostasisGO:0006875780.011
response to oxidative stressGO:0006979990.011
replication fork protectionGO:004847860.011
dna biosynthetic processGO:0071897330.011
protein modification by small protein conjugation or removalGO:00706471720.011
establishment of nucleus localizationGO:0040023220.011
cellular modified amino acid metabolic processGO:0006575510.011
double strand break repair via nonhomologous end joiningGO:0006303270.011
negative regulation of cell communicationGO:0010648330.011
cellular response to extracellular stimulusGO:00316681500.011
sister chromatid segregationGO:0000819930.011
mitotic g2 m transition checkpointGO:004481830.011
response to organic cyclic compoundGO:001407010.011
response to nutrient levelsGO:00316671500.011
regulation of nuclear divisionGO:00517831030.010
ras protein signal transductionGO:0007265290.010
cellular protein catabolic processGO:00442572130.010
nucleoside triphosphate metabolic processGO:00091413640.010
gtp metabolic processGO:00460391070.010
response to osmotic stressGO:0006970830.010

MCM4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
inherited metabolic disorderDOID:65500.018
disease of metabolismDOID:001466700.018