IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

107 known processes

SGV1 (YPR161C)

Sgv1p

(Aliases: BUR1)

SGD: S000006365
Entrez: 856290
UniProtKB: P23293

Process Predictions
Disease Predictions

SGV1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
nuclear division	GO:0000280	263	0.974
protein modification by small protein conjugation or removal	GO:0070647	172	0.860
meiotic nuclear division	GO:0007126	163	0.851
organelle fission	GO:0048285	272	0.765
negative regulation of gene expression	GO:0010629	312	0.746
negative regulation of biosynthetic process	GO:0009890	312	0.720	Human
positive regulation of biosynthetic process	GO:0009891	336	0.718
meiotic cell cycle	GO:0051321	272	0.716
chromosome segregation	GO:0007059	159	0.706
dna templated transcription elongation	GO:0006354	91	0.679	Fly
cellular macromolecule catabolic process	GO:0044265	363	0.640
regulation of chromosome organization	GO:0033044	66	0.634
macromolecule catabolic process	GO:0009057	383	0.613
mitotic cell cycle process	GO:1903047	294	0.603
negative regulation of macromolecule metabolic process	GO:0010605	375	0.578	Human
mitotic nuclear division	GO:0007067	131	0.562
regulation of protein metabolic process	GO:0051246	237	0.518
regulation of cellular protein metabolic process	GO:0032268	232	0.516
response to organic substance	GO:0010033	182	0.491	Human
regulation of translation	GO:0006417	89	0.454
positive regulation of macromolecule metabolic process	GO:0010604	394	0.440
negative regulation of cellular metabolic process	GO:0031324	407	0.433	Human
cation homeostasis	GO:0055080	105	0.384
protein modification by small protein conjugation	GO:0032446	144	0.379
positive regulation of cellular biosynthetic process	GO:0031328	336	0.371
meiosis i	GO:0007127	92	0.371
microtubule organizing center organization	GO:0031023	33	0.350
cellular response to organic substance	GO:0071310	159	0.338	Human
translation	GO:0006412	230	0.338
regulation of organelle organization	GO:0033043	243	0.330
mrna processing	GO:0006397	185	0.322
cellular response to dna damage stimulus	GO:0006974	287	0.315	Human
protein ubiquitination	GO:0016567	118	0.308
response to chemical	GO:0042221	390	0.302	Human
negative regulation of rna metabolic process	GO:0051253	262	0.299
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.299
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.294
regulation of cellular component organization	GO:0051128	334	0.282
negative regulation of cellular biosynthetic process	GO:0031327	312	0.277	Human
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.273
regulation of cellular catabolic process	GO:0031329	195	0.273
cellular response to chemical stimulus	GO:0070887	315	0.273	Human
response to abiotic stimulus	GO:0009628	159	0.261	Fly
cytokinesis	GO:0000910	92	0.260
protein phosphorylation	GO:0006468	197	0.253
mitotic cell cycle	GO:0000278	306	0.253	Fly
multi organism process	GO:0051704	233	0.247
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.246	Human
dna repair	GO:0006281	236	0.245	Human
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.238	Human
cell cycle phase transition	GO:0044770	144	0.237
positive regulation of gene expression	GO:0010628	321	0.235
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.232	Human
mrna 3 end processing	GO:0031124	54	0.230
modification dependent protein catabolic process	GO:0019941	181	0.226
regulation of cellular component size	GO:0032535	50	0.226
ribonucleoprotein complex subunit organization	GO:0071826	152	0.225
transcription elongation from rna polymerase ii promoter	GO:0006368	81	0.212	Fly
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.212
dna dependent dna replication	GO:0006261	115	0.203	Human
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.194
ubiquitin dependent protein catabolic process	GO:0006511	181	0.192
regulation of dna templated transcription elongation	GO:0032784	44	0.186
negative regulation of transcription dna templated	GO:0045892	258	0.165
protein catabolic process	GO:0030163	221	0.164
meiotic cell cycle process	GO:1903046	229	0.162
mrna metabolic process	GO:0016071	269	0.159
positive regulation of rna metabolic process	GO:0051254	294	0.158
cell cycle checkpoint	GO:0000075	82	0.155
negative regulation of catabolic process	GO:0009895	43	0.155
regulation of catabolic process	GO:0009894	199	0.153
positive regulation of transcription dna templated	GO:0045893	286	0.151
positive regulation of dna templated transcription elongation	GO:0032786	42	0.146
nuclear transport	GO:0051169	165	0.145
posttranscriptional regulation of gene expression	GO:0010608	115	0.143
proteolysis	GO:0006508	268	0.141
negative regulation of cellular component organization	GO:0051129	109	0.139
intracellular signal transduction	GO:0035556	112	0.137
chromatin modification	GO:0016568	200	0.136
nucleus organization	GO:0006997	62	0.136
nucleotide excision repair	GO:0006289	50	0.135
regulation of biological quality	GO:0065008	391	0.133	Fly
autophagy	GO:0006914	106	0.132
carboxylic acid metabolic process	GO:0019752	338	0.131
nuclear transcribed mrna catabolic process	GO:0000956	89	0.128
sister chromatid segregation	GO:0000819	93	0.125
lipid metabolic process	GO:0006629	269	0.125
regulation of cell cycle process	GO:0010564	150	0.121	Human
negative regulation of rna biosynthetic process	GO:1902679	260	0.121
rna localization	GO:0006403	112	0.117
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.115
positive regulation of rna biosynthetic process	GO:1902680	286	0.110
rna catabolic process	GO:0006401	118	0.109
ribonucleoprotein complex assembly	GO:0022618	143	0.105
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.100
regulation of cell division	GO:0051302	113	0.099
positive regulation of translation	GO:0045727	34	0.098
cell division	GO:0051301	205	0.097
negative regulation of chromosome organization	GO:2001251	39	0.096
rna 3 end processing	GO:0031123	88	0.094
positive regulation of cellular protein metabolic process	GO:0032270	89	0.093
cellular protein catabolic process	GO:0044257	213	0.093
cellular response to extracellular stimulus	GO:0031668	150	0.089
negative regulation of organelle organization	GO:0010639	103	0.088
cellular chemical homeostasis	GO:0055082	123	0.087
negative regulation of cellular protein metabolic process	GO:0032269	85	0.086
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	40	0.086
chemical homeostasis	GO:0048878	137	0.086
covalent chromatin modification	GO:0016569	119	0.085
gene silencing	GO:0016458	151	0.082
regulation of chromatin modification	GO:1903308	23	0.080
rrna processing	GO:0006364	227	0.079
positive regulation of catabolic process	GO:0009896	135	0.078
organic acid metabolic process	GO:0006082	352	0.076
mrna transport	GO:0051028	60	0.075
regulation of chromatin organization	GO:1902275	23	0.073
multi organism reproductive process	GO:0044703	216	0.073
negative regulation of mitotic cell cycle	GO:0045930	63	0.072
single organism catabolic process	GO:0044712	619	0.071
cellular homeostasis	GO:0019725	138	0.071
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.070
aromatic compound catabolic process	GO:0019439	491	0.070
negative regulation of cell cycle process	GO:0010948	86	0.067	Human
regulation of mitotic cell cycle	GO:0007346	107	0.067
cytokinetic process	GO:0032506	78	0.066
rna transport	GO:0050658	92	0.065
spindle checkpoint	GO:0031577	35	0.065
chromatin organization	GO:0006325	242	0.065
negative regulation of cellular catabolic process	GO:0031330	43	0.065
positive regulation of protein metabolic process	GO:0051247	93	0.065
negative regulation of cell cycle	GO:0045786	91	0.064	Human
ion homeostasis	GO:0050801	118	0.064
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.062
mitochondrion localization	GO:0051646	29	0.062
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	38	0.060
negative regulation of cell division	GO:0051782	66	0.059
regulation of histone modification	GO:0031056	18	0.059
negative regulation of mitosis	GO:0045839	39	0.059
dna replication	GO:0006260	147	0.058	Human
regulation of meiotic cell cycle	GO:0051445	43	0.058
regulation of cell cycle	GO:0051726	195	0.057
regulation of gene expression epigenetic	GO:0040029	147	0.057
nucleocytoplasmic transport	GO:0006913	163	0.055
exit from mitosis	GO:0010458	37	0.055
endosomal transport	GO:0016197	86	0.053
phosphorylation of rna polymerase ii c terminal domain	GO:0070816	20	0.052
sister chromatid cohesion	GO:0007062	49	0.052
chromosome organization involved in meiosis	GO:0070192	32	0.050
meiotic chromosome segregation	GO:0045132	31	0.050
nucleic acid transport	GO:0050657	94	0.049
rna export from nucleus	GO:0006405	88	0.049
regulation of nuclear division	GO:0051783	103	0.049
regulation of cellular ketone metabolic process	GO:0010565	42	0.049
mrna export from nucleus	GO:0006406	60	0.049
regulation of microtubule based process	GO:0032886	32	0.048
regulation of cell size	GO:0008361	30	0.048
cation transport	GO:0006812	166	0.048
cellular cation homeostasis	GO:0030003	100	0.048
negative regulation of protein metabolic process	GO:0051248	85	0.047
regulation of multi organism process	GO:0043900	20	0.044
double strand break repair via homologous recombination	GO:0000724	54	0.044
regulation of anatomical structure size	GO:0090066	50	0.043
mitotic cell cycle phase transition	GO:0044772	141	0.043
transcription from rna polymerase i promoter	GO:0006360	63	0.043
positive regulation of organelle organization	GO:0010638	85	0.043
mitotic sister chromatid segregation	GO:0000070	85	0.042
mrna catabolic process	GO:0006402	93	0.042
regulation of metal ion transport	GO:0010959	2	0.042
regulation of response to external stimulus	GO:0032101	20	0.041
establishment of organelle localization	GO:0051656	96	0.041
histone modification	GO:0016570	119	0.040
sexual reproduction	GO:0019953	216	0.040
regulation of protein ubiquitination	GO:0031396	20	0.038
negative regulation of gene expression epigenetic	GO:0045814	147	0.038
recombinational repair	GO:0000725	64	0.037
cellular protein complex disassembly	GO:0043624	42	0.037
single organism signaling	GO:0044700	208	0.037
modification dependent macromolecule catabolic process	GO:0043632	203	0.036
regulation of response to stimulus	GO:0048583	157	0.036	Human
protein alkylation	GO:0008213	48	0.035
dna conformation change	GO:0071103	98	0.035
microtubule based process	GO:0007017	117	0.035
regulation of dna dependent dna replication	GO:0090329	37	0.035	Human
regulation of protein modification process	GO:0031399	110	0.034
response to organic cyclic compound	GO:0014070	1	0.034
cellular response to starvation	GO:0009267	90	0.034
organelle localization	GO:0051640	128	0.034
positive regulation of cellular component organization	GO:0051130	116	0.033
cellular metal ion homeostasis	GO:0006875	78	0.032
response to nitrogen compound	GO:1901698	18	0.032
regulation of response to osmotic stress	GO:0047484	11	0.032
nucleobase containing compound catabolic process	GO:0034655	479	0.032
regulation of mitosis	GO:0007088	65	0.031
maintenance of protein location in cell	GO:0032507	50	0.031
signaling	GO:0023052	208	0.031
negative regulation of multi organism process	GO:0043901	6	0.030
membrane organization	GO:0061024	276	0.030
aging	GO:0007568	71	0.029
mitochondrion inheritance	GO:0000001	21	0.029
lipid biosynthetic process	GO:0008610	170	0.029
mitotic cell cycle checkpoint	GO:0007093	56	0.029
programmed cell death	GO:0012501	30	0.029
response to uv	GO:0009411	4	0.028
mitotic recombination	GO:0006312	55	0.028
histone ubiquitination	GO:0016574	17	0.028
cellular response to pheromone	GO:0071444	88	0.028
maintenance of location in cell	GO:0051651	58	0.028
nucleobase containing compound transport	GO:0015931	124	0.028
single organism developmental process	GO:0044767	258	0.028	Worm Fly
endocytosis	GO:0006897	90	0.027
protein modification by small protein removal	GO:0070646	29	0.026
phosphorylation	GO:0016310	291	0.026
nitrogen compound transport	GO:0071705	212	0.025
histone lysine methylation	GO:0034968	26	0.025
cellular ketone metabolic process	GO:0042180	63	0.025
negative regulation of response to stimulus	GO:0048585	40	0.025
regulation of cytoskeleton organization	GO:0051493	63	0.025
regulation of cellular localization	GO:0060341	50	0.024
signal transduction	GO:0007165	208	0.024
chromatin remodeling	GO:0006338	80	0.024
mitotic spindle checkpoint	GO:0071174	34	0.024
conjugation	GO:0000746	107	0.023
establishment of nucleus localization	GO:0040023	22	0.023
homeostatic process	GO:0042592	227	0.023
karyogamy	GO:0000741	17	0.023
rna capping	GO:0036260	13	0.023
protein depolymerization	GO:0051261	21	0.023
peroxisome organization	GO:0007031	68	0.023
chromatin silencing	GO:0006342	147	0.023
sexual sporulation	GO:0034293	113	0.022
establishment of rna localization	GO:0051236	92	0.022
dna templated transcription termination	GO:0006353	42	0.021
nuclear export	GO:0051168	124	0.021
maintenance of protein location	GO:0045185	53	0.021
dna recombination	GO:0006310	172	0.021
anatomical structure morphogenesis	GO:0009653	160	0.021	Fly
multi organism cellular process	GO:0044764	120	0.020
dephosphorylation	GO:0016311	127	0.020
rrna metabolic process	GO:0016072	244	0.020
gtp metabolic process	GO:0046039	107	0.020
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.020
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.020
regulation of cellular response to stress	GO:0080135	50	0.020	Human
regulation of response to nutrient levels	GO:0032107	20	0.020
developmental process	GO:0032502	261	0.019	Worm Fly
positive regulation of dna metabolic process	GO:0051054	26	0.019
metal ion transport	GO:0030001	75	0.019
peptidyl amino acid modification	GO:0018193	116	0.019
response to heat	GO:0009408	69	0.018	Fly
positive regulation of lipid catabolic process	GO:0050996	4	0.018
microtubule cytoskeleton organization involved in mitosis	GO:1902850	13	0.018
spindle organization	GO:0007051	37	0.018
establishment of protein localization	GO:0045184	367	0.018
metaphase plate congression	GO:0051310	8	0.017
mrna splicing via spliceosome	GO:0000398	108	0.017
regulation of transcription involved in g1 s transition of mitotic cell cycle	GO:0000083	27	0.017
amine metabolic process	GO:0009308	51	0.017
reproductive process in single celled organism	GO:0022413	145	0.017
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.017
dna packaging	GO:0006323	55	0.017
g1 s transition of mitotic cell cycle	GO:0000082	64	0.017
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.017	Human
conjugation with cellular fusion	GO:0000747	106	0.016
cellular response to nutrient levels	GO:0031669	144	0.016
dna damage checkpoint	GO:0000077	29	0.016
nucleoside catabolic process	GO:0009164	335	0.016
response to oxygen containing compound	GO:1901700	61	0.016
response to nutrient levels	GO:0031667	150	0.016
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	137	0.016
nuclear transcribed mrna poly a tail shortening	GO:0000289	14	0.016
mitochondrion distribution	GO:0048311	21	0.016
regulation of microtubule cytoskeleton organization	GO:0070507	32	0.016
regulation of conjugation with cellular fusion	GO:0031137	16	0.015
vacuole organization	GO:0007033	75	0.015
cellular response to endogenous stimulus	GO:0071495	22	0.015
steroid biosynthetic process	GO:0006694	35	0.015
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.014
spindle assembly involved in mitosis	GO:0090307	4	0.014
synapsis	GO:0007129	19	0.014
positive regulation of cytoskeleton organization	GO:0051495	39	0.014
vesicle mediated transport	GO:0016192	335	0.014
anatomical structure development	GO:0048856	160	0.014	Worm Fly
organelle inheritance	GO:0048308	51	0.014
histone h3 k4 methylation	GO:0051568	18	0.013
reciprocal meiotic recombination	GO:0007131	54	0.013
spindle pole body organization	GO:0051300	33	0.013
sporulation	GO:0043934	132	0.013
response to temperature stimulus	GO:0009266	74	0.013	Fly
cell communication	GO:0007154	345	0.013
regulation of protein localization	GO:0032880	62	0.013
negative regulation of cell cycle phase transition	GO:1901988	59	0.013
regulation of chromosome segregation	GO:0051983	44	0.013
proteasomal protein catabolic process	GO:0010498	141	0.012
protein localization to membrane	GO:0072657	102	0.012
organic cyclic compound catabolic process	GO:1901361	499	0.012
golgi vesicle transport	GO:0048193	188	0.012
chromosome localization	GO:0050000	20	0.012
negative regulation of dna metabolic process	GO:0051053	36	0.012	Human
single organism membrane organization	GO:0044802	275	0.012
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.012
cellular carbohydrate metabolic process	GO:0044262	135	0.012
metal ion homeostasis	GO:0055065	79	0.012
regulation of conjugation	GO:0046999	16	0.012
negative regulation of protein maturation	GO:1903318	33	0.012
developmental process involved in reproduction	GO:0003006	159	0.012
single organism cellular localization	GO:1902580	375	0.012
budding cell apical bud growth	GO:0007118	19	0.012
cell wall organization or biogenesis	GO:0071554	190	0.011
regulation of transcription by pheromones	GO:0009373	14	0.011
oxoacid metabolic process	GO:0043436	351	0.011
death	GO:0016265	30	0.011
regulation of lipid catabolic process	GO:0050994	4	0.011
reproductive process	GO:0022414	248	0.011
negative regulation of cytoskeleton organization	GO:0051494	24	0.011
microtubule polymerization or depolymerization	GO:0031109	36	0.011
ascospore formation	GO:0030437	107	0.011
ribosome biogenesis	GO:0042254	335	0.011
cellular response to external stimulus	GO:0071496	150	0.011
microtubule cytoskeleton organization	GO:0000226	109	0.011
carbohydrate metabolic process	GO:0005975	252	0.011
positive regulation of gene expression epigenetic	GO:0045815	25	0.011
positive regulation of cellular catabolic process	GO:0031331	128	0.011
regulation of protein modification by small protein conjugation or removal	GO:1903320	29	0.011
gene silencing by rna	GO:0031047	3	0.011
regulation of autophagy	GO:0010506	18	0.011
synaptonemal complex organization	GO:0070193	16	0.011
regulation of cellular amine metabolic process	GO:0033238	21	0.011
translational initiation	GO:0006413	56	0.011
positive regulation of intracellular protein transport	GO:0090316	3	0.010
negative regulation of protein modification process	GO:0031400	37	0.010
cytokinetic cell separation	GO:0000920	21	0.010
7 methylguanosine rna capping	GO:0009452	11	0.010
regulation of meiosis	GO:0040020	42	0.010
cellular response to uv	GO:0034644	3	0.010
cell aging	GO:0007569	70	0.010
regulation of cell cycle phase transition	GO:1901987	70	0.010

SGV1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	nervous system disease	DOID:863	0	0.011
	disease of anatomical entity	DOID:7	0	0.011

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