IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

19 known processes

ARC35 (YNR035C)

Arc35p

(Aliases: END9)

SGD: S000005318
Entrez: 855771
UniProtKB: P53731

Process Predictions
Disease Predictions

ARC35 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
actin filament based process	GO:0030029	104	0.992
actin cytoskeleton organization	GO:0030036	100	0.991
cytoskeleton organization	GO:0007010	230	0.916
regulation of actin polymerization or depolymerization	GO:0008064	19	0.885	Human
actin filament organization	GO:0007015	56	0.860	Human
positive regulation of protein complex assembly	GO:0031334	39	0.825	Human
protein polymerization	GO:0051258	51	0.702	Human
regulation of cellular component organization	GO:0051128	334	0.650	Human Fly
actin filament polymerization	GO:0030041	16	0.647	Human
cellular component morphogenesis	GO:0032989	97	0.636	Fly
regulation of cellular component biogenesis	GO:0044087	112	0.621	Human
regulation of actin filament polymerization	GO:0030833	19	0.605	Human
actin polymerization or depolymerization	GO:0008154	17	0.588	Human
cortical actin cytoskeleton organization	GO:0030866	11	0.540	Fly
meiotic cell cycle process	GO:1903046	229	0.536
meiotic cell cycle	GO:0051321	272	0.518
establishment of protein localization	GO:0045184	367	0.460
protein complex biogenesis	GO:0070271	314	0.434	Human
regulation of actin filament length	GO:0030832	19	0.428	Human
regulation of actin cytoskeleton organization	GO:0032956	31	0.417	Human
regulation of organelle organization	GO:0033043	243	0.367	Human
developmental process	GO:0032502	261	0.365	Fly
positive regulation of protein polymerization	GO:0032273	22	0.350	Human
organelle localization	GO:0051640	128	0.343
regulation of actin filament based process	GO:0032970	31	0.333	Human
protein transport	GO:0015031	345	0.326
cell morphogenesis	GO:0000902	30	0.318	Fly
regulation of protein complex assembly	GO:0043254	77	0.313	Human
cell development	GO:0048468	107	0.305
anatomical structure development	GO:0048856	160	0.304	Fly
regulation of cytoskeleton organization	GO:0051493	63	0.291	Human
membrane organization	GO:0061024	276	0.287
positive regulation of cellular component biogenesis	GO:0044089	45	0.286	Human
single organism cellular localization	GO:1902580	375	0.267
regulation of protein polymerization	GO:0032271	33	0.262	Human
single organism catabolic process	GO:0044712	619	0.258
negative regulation of organelle organization	GO:0010639	103	0.244
heterocycle catabolic process	GO:0046700	494	0.241
positive regulation of actin filament polymerization	GO:0030838	10	0.239	Human
positive regulation of cytoskeleton organization	GO:0051495	39	0.213	Human
endocytosis	GO:0006897	90	0.212
anatomical structure morphogenesis	GO:0009653	160	0.210	Fly
chromosome segregation	GO:0007059	159	0.204
regulation of biological quality	GO:0065008	391	0.199	Human Fly
reproductive process in single celled organism	GO:0022413	145	0.196
cellular developmental process	GO:0048869	191	0.195	Fly
arp2 3 complex mediated actin nucleation	GO:0034314	7	0.192	Human
positive regulation of cellular component organization	GO:0051130	116	0.190	Human
actin cortical patch assembly	GO:0000147	9	0.186
negative regulation of cell cycle process	GO:0010948	86	0.167
protein complex assembly	GO:0006461	302	0.164	Human
cell division	GO:0051301	205	0.156
intracellular protein transport	GO:0006886	319	0.155
actin nucleation	GO:0045010	10	0.148	Human
nuclear division	GO:0000280	263	0.145
regulation of signal transduction	GO:0009966	114	0.142
reproductive process	GO:0022414	248	0.131
phosphorylation	GO:0016310	291	0.131
nucleoside phosphate metabolic process	GO:0006753	458	0.129
chromosome localization	GO:0050000	20	0.128
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.123
single organism developmental process	GO:0044767	258	0.119	Fly
cell differentiation	GO:0030154	161	0.118	Fly
developmental process involved in reproduction	GO:0003006	159	0.118
negative regulation of cellular biosynthetic process	GO:0031327	312	0.113
single organism reproductive process	GO:0044702	159	0.106
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.103
regulation of anatomical structure size	GO:0090066	50	0.101	Human
nucleobase containing compound catabolic process	GO:0034655	479	0.099
aromatic compound catabolic process	GO:0019439	491	0.099
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.099
cellular component movement	GO:0006928	20	0.097
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.094
regulation of cellular component size	GO:0032535	50	0.092	Human
protein targeting	GO:0006605	272	0.092
sexual reproduction	GO:0019953	216	0.091
single organism signaling	GO:0044700	208	0.090	Fly
cellular nitrogen compound catabolic process	GO:0044270	494	0.088
positive regulation of organelle organization	GO:0010638	85	0.087	Human
cortical cytoskeleton organization	GO:0030865	11	0.086	Fly
regulation of response to stimulus	GO:0048583	157	0.086
negative regulation of cellular component organization	GO:0051129	109	0.085
negative regulation of macromolecule metabolic process	GO:0010605	375	0.081
nucleotide catabolic process	GO:0009166	330	0.079
purine ribonucleoside monophosphate catabolic process	GO:0009169	224	0.078
regulation of cell cycle process	GO:0010564	150	0.077
regulation of cellular protein metabolic process	GO:0032268	232	0.077
signaling	GO:0023052	208	0.077	Fly
organelle fission	GO:0048285	272	0.074
regulation of cell cycle	GO:0051726	195	0.071
cellular protein complex assembly	GO:0043623	209	0.071	Human
mitochondrion localization	GO:0051646	29	0.070
protein localization to membrane	GO:0072657	102	0.070
negative regulation of cell division	GO:0051782	66	0.069
positive regulation of macromolecule metabolic process	GO:0010604	394	0.069
signal transduction	GO:0007165	208	0.067
sporulation	GO:0043934	132	0.067
negative regulation of biosynthetic process	GO:0009890	312	0.066
cell cycle phase transition	GO:0044770	144	0.065
sexual sporulation	GO:0034293	113	0.064
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.063
positive regulation of signaling	GO:0023056	20	0.062
nucleobase containing small molecule metabolic process	GO:0055086	491	0.059
post golgi vesicle mediated transport	GO:0006892	72	0.059
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.055
response to chemical	GO:0042221	390	0.055
golgi to plasma membrane transport	GO:0006893	33	0.054
fungal type cell wall assembly	GO:0071940	53	0.053
regulation of cell communication	GO:0010646	124	0.051
regulation of cell division	GO:0051302	113	0.051
meiotic chromosome segregation	GO:0045132	31	0.050
negative regulation of cellular metabolic process	GO:0031324	407	0.050
nucleoside catabolic process	GO:0009164	335	0.049
negative regulation of actin filament polymerization	GO:0030837	10	0.047
regulation of localization	GO:0032879	127	0.046
spore wall assembly	GO:0042244	52	0.045
purine nucleotide metabolic process	GO:0006163	376	0.044
negative regulation of gene expression	GO:0010629	312	0.043
organonitrogen compound catabolic process	GO:1901565	404	0.043
positive regulation of rna metabolic process	GO:0051254	294	0.043
establishment of organelle localization	GO:0051656	96	0.043
negative regulation of cell cycle	GO:0045786	91	0.042
multi organism reproductive process	GO:0044703	216	0.041
regulation of catalytic activity	GO:0050790	307	0.041
response to organic substance	GO:0010033	182	0.040
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.040
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.039
dna repair	GO:0006281	236	0.039
vacuolar transport	GO:0007034	145	0.039
meiotic nuclear division	GO:0007126	163	0.038
cell communication	GO:0007154	345	0.038	Fly
regulation of developmental process	GO:0050793	30	0.037	Fly
macromolecule catabolic process	GO:0009057	383	0.037
cellular component disassembly	GO:0022411	86	0.037
protein phosphorylation	GO:0006468	197	0.036
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.036
ascospore formation	GO:0030437	107	0.035
protein targeting to vacuole	GO:0006623	91	0.035
actin cytoskeleton reorganization	GO:0031532	11	0.035
organic cyclic compound catabolic process	GO:1901361	499	0.035
positive regulation of gene expression	GO:0010628	321	0.035
purine nucleoside monophosphate catabolic process	GO:0009128	224	0.035
purine ribonucleotide metabolic process	GO:0009150	372	0.034
regulation of nuclear division	GO:0051783	103	0.034
positive regulation of signal transduction	GO:0009967	20	0.034
regulation of phosphorus metabolic process	GO:0051174	230	0.034
protein localization to nucleus	GO:0034504	74	0.034
organophosphate catabolic process	GO:0046434	338	0.034
positive regulation of biosynthetic process	GO:0009891	336	0.033
mitotic cell cycle phase transition	GO:0044772	141	0.033
ribose phosphate metabolic process	GO:0019693	384	0.031
atp catabolic process	GO:0006200	224	0.031
purine nucleoside metabolic process	GO:0042278	380	0.030
positive regulation of cytoplasmic transport	GO:1903651	4	0.030
regulation of signaling	GO:0023051	119	0.029
ribonucleoside catabolic process	GO:0042454	332	0.029
purine nucleoside catabolic process	GO:0006152	330	0.029
ribonucleotide catabolic process	GO:0009261	327	0.029
actin cortical patch organization	GO:0044396	10	0.029
positive regulation of cellular biosynthetic process	GO:0031328	336	0.028
actin filament depolymerization	GO:0030042	9	0.028
response to oxidative stress	GO:0006979	99	0.028
purine nucleoside monophosphate metabolic process	GO:0009126	262	0.028
cell projection assembly	GO:0030031	8	0.028	Human Fly
establishment of protein localization to vacuole	GO:0072666	91	0.028
nucleoside metabolic process	GO:0009116	394	0.027
negative regulation of actin filament depolymerization	GO:0030835	7	0.027
nucleoside phosphate catabolic process	GO:1901292	331	0.026
regulation of protein metabolic process	GO:0051246	237	0.025
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.025
cell wall biogenesis	GO:0042546	93	0.025
regulation of catabolic process	GO:0009894	199	0.025
regulation of cell cycle phase transition	GO:1901987	70	0.024
regulation of actin filament depolymerization	GO:0030834	7	0.024
positive regulation of intracellular transport	GO:0032388	4	0.024
cell cycle g2 m phase transition	GO:0044839	39	0.024
cellular carbohydrate metabolic process	GO:0044262	135	0.024
regulation of protein localization	GO:0032880	62	0.024
positive regulation of response to stimulus	GO:0048584	37	0.024
nucleoside triphosphate catabolic process	GO:0009143	329	0.023
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.023
ribonucleotide metabolic process	GO:0009259	377	0.023
posttranscriptional regulation of gene expression	GO:0010608	115	0.023
plasma membrane organization	GO:0007009	21	0.023
purine nucleotide catabolic process	GO:0006195	328	0.023
response to oxygen containing compound	GO:1901700	61	0.023
mitochondrion inheritance	GO:0000001	21	0.023
cellular response to abiotic stimulus	GO:0071214	62	0.023
response to osmotic stress	GO:0006970	83	0.022
purine ribonucleoside metabolic process	GO:0046128	380	0.022
establishment of protein localization to organelle	GO:0072594	278	0.022
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.022
nucleotide metabolic process	GO:0009117	453	0.022
negative regulation of cell cycle phase transition	GO:1901988	59	0.021
organelle assembly	GO:0070925	118	0.021
peptidyl amino acid modification	GO:0018193	116	0.021
fungal type cell wall organization or biogenesis	GO:0071852	169	0.020
vesicle mediated transport	GO:0016192	335	0.020
external encapsulating structure organization	GO:0045229	146	0.020
covalent chromatin modification	GO:0016569	119	0.020
regulation of phosphorylation	GO:0042325	86	0.020
cell wall assembly	GO:0070726	54	0.020
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.019
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.019
regulation of dna templated transcription elongation	GO:0032784	44	0.019
regulation of phosphate metabolic process	GO:0019220	230	0.018
maintenance of location	GO:0051235	66	0.018
multi organism process	GO:0051704	233	0.018
barbed end actin filament capping	GO:0051016	7	0.018
negative regulation of protein depolymerization	GO:1901880	12	0.018
response to abiotic stimulus	GO:0009628	159	0.017
internal peptidyl lysine acetylation	GO:0018393	52	0.017
fungal type cell wall organization	GO:0031505	145	0.017
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.017
nucleoside monophosphate metabolic process	GO:0009123	267	0.017
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.017
regulation of anatomical structure morphogenesis	GO:0022603	17	0.017	Fly
regulation of metal ion transport	GO:0010959	2	0.017
protein complex disassembly	GO:0043241	70	0.017
spore wall biogenesis	GO:0070590	52	0.017
ribonucleoside metabolic process	GO:0009119	389	0.016
cytokinesis	GO:0000910	92	0.016
regulation of molecular function	GO:0065009	320	0.016
protein localization to vacuole	GO:0072665	92	0.016
glycosyl compound catabolic process	GO:1901658	335	0.016
positive regulation of cell communication	GO:0010647	28	0.016
programmed cell death	GO:0012501	30	0.016
ribonucleoside monophosphate catabolic process	GO:0009158	224	0.016
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.016
glycosyl compound metabolic process	GO:1901657	398	0.016
reproduction of a single celled organism	GO:0032505	191	0.016
negative regulation of protein metabolic process	GO:0051248	85	0.016
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.015
nucleoside monophosphate catabolic process	GO:0009125	224	0.015
mitotic nuclear division	GO:0007067	131	0.015
carbohydrate derivative catabolic process	GO:1901136	339	0.014
regulation of protein modification process	GO:0031399	110	0.014
energy derivation by oxidation of organic compounds	GO:0015980	125	0.014
ascospore wall biogenesis	GO:0070591	52	0.014
actin filament capping	GO:0051693	7	0.014
nuclear import	GO:0051170	57	0.014
regulation of cellular catabolic process	GO:0031329	195	0.014
negative regulation of rna biosynthetic process	GO:1902679	260	0.013
nucleic acid phosphodiester bond hydrolysis	GO:0090305	194	0.013
alcohol biosynthetic process	GO:0046165	75	0.013
regulation of hydrolase activity	GO:0051336	133	0.013
mrna metabolic process	GO:0016071	269	0.013
positive regulation of rna biosynthetic process	GO:1902680	286	0.013
cellular response to organic substance	GO:0071310	159	0.012
regulation of cellular amine metabolic process	GO:0033238	21	0.012
spindle localization	GO:0051653	14	0.012
positive regulation of hydrolase activity	GO:0051345	112	0.012
regulation of kinase activity	GO:0043549	71	0.012
fungal type cell wall biogenesis	GO:0009272	80	0.012
organic hydroxy compound biosynthetic process	GO:1901617	81	0.012
carbohydrate derivative metabolic process	GO:1901135	549	0.012
establishment of protein localization to membrane	GO:0090150	99	0.012
regulation of cell shape	GO:0008360	4	0.011	Fly
atp metabolic process	GO:0046034	251	0.011
purine containing compound metabolic process	GO:0072521	400	0.011
g2 m transition of mitotic cell cycle	GO:0000086	38	0.011
macromolecular complex disassembly	GO:0032984	80	0.011
cell wall organization or biogenesis	GO:0071554	190	0.011
mitotic cell cycle	GO:0000278	306	0.011
intracellular signal transduction	GO:0035556	112	0.011
maintenance of protein location	GO:0045185	53	0.011
negative regulation of cell communication	GO:0010648	33	0.011
protein import into nucleus	GO:0006606	55	0.011
microtubule based process	GO:0007017	117	0.011
histone acetylation	GO:0016573	51	0.011
positive regulation of molecular function	GO:0044093	185	0.010
cellular metal ion homeostasis	GO:0006875	78	0.010
organic hydroxy compound metabolic process	GO:1901615	125	0.010
organelle inheritance	GO:0048308	51	0.010
stress activated protein kinase signaling cascade	GO:0031098	4	0.010
mrna catabolic process	GO:0006402	93	0.010
vesicle organization	GO:0016050	68	0.010
response to organic cyclic compound	GO:0014070	1	0.010
negative regulation of chromosome organization	GO:2001251	39	0.010
cellular response to oxidative stress	GO:0034599	94	0.010

ARC35 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.026

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