Saccharomyces cerevisiae

81 known processes

RAD53 (YPL153C)

Rad53p

(Aliases: MEC2,SPK1,LSD1)

RAD53 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
double strand break repairGO:00063021050.999
dna repairGO:00062812360.999
dna recombinationGO:00063101720.999
meiosis iGO:0007127920.998
dna conformation changeGO:0071103980.992
recombinational repairGO:0000725640.989
double strand break repair via homologous recombinationGO:0000724540.988
cellular response to dna damage stimulusGO:00069742870.984
reciprocal meiotic recombinationGO:0007131540.971
mitotic cell cycle processGO:19030472940.970
negative regulation of cell cycle processGO:0010948860.957
Yeast
telomere organizationGO:0032200750.950
mitotic cell cycleGO:00002783060.948
dna replicationGO:00062601470.941
reciprocal dna recombinationGO:0035825540.931
mitotic sister chromatid segregationGO:0000070850.923
negative regulation of mitotic cell cycleGO:0045930630.920
negative regulation of cell cycleGO:0045786910.914
Yeast
nuclear divisionGO:00002802630.907
Yeast
regulation of dna metabolic processGO:00510521000.890
Yeast
dna integrity checkpointGO:0031570410.882
telomere maintenanceGO:0000723740.878
regulation of cell cycle processGO:00105641500.875
Yeast
chromosome condensationGO:0030261190.856
dna packagingGO:0006323550.851
cell cycle checkpointGO:0000075820.842
dna damage checkpointGO:0000077290.841
protein complex biogenesisGO:00702713140.832
mitotic sister chromatid cohesionGO:0007064380.783
regulation of cell cycleGO:00517261950.777
Yeast
negative regulation of mitotic cell cycle phase transitionGO:1901991570.707
meiotic nuclear divisionGO:00071261630.698
Yeast
dna dependent dna replicationGO:00062611150.687
negative regulation of cell cycle phase transitionGO:1901988590.667
meiotic cell cycle processGO:19030462290.660
Yeast
mitotic cell cycle checkpointGO:0007093560.657
regulation of dna replicationGO:0006275510.622
Yeast
dna replication initiationGO:0006270480.610
chromosome segregationGO:00070591590.601
negative regulation of cellular metabolic processGO:00313244070.585
non recombinational repairGO:0000726330.581
regulation of g2 m transition of mitotic cell cycleGO:001038980.579
negative regulation of dna metabolic processGO:0051053360.569
Yeast
mitotic cell cycle phase transitionGO:00447721410.560
organelle fissionGO:00482852720.549
Yeast
negative regulation of nucleobase containing compound metabolic processGO:00459342950.546
Yeast
double strand break repair via break induced replicationGO:0000727250.542
protein phosphorylationGO:00064681970.527
sister chromatid cohesionGO:0007062490.484
phosphorylationGO:00163102910.476
regulation of chromosome organizationGO:0033044660.441
reproductive processGO:00224142480.436
dna unwinding involved in dna replicationGO:0006268130.432
regulation of cellular component organizationGO:00511283340.430
Yeast
single organism signalingGO:00447002080.423
Yeast
regulation of cellular protein metabolic processGO:00322682320.411
Yeast
organic cyclic compound catabolic processGO:19013614990.396
cell cycle g1 s phase transitionGO:0044843640.354
regulation of cell cycle phase transitionGO:1901987700.341
regulation of organelle organizationGO:00330432430.341
Yeast
negative regulation of dna replicationGO:0008156150.330
Yeast
telomere maintenance via telomeraseGO:0007004210.319
heterocycle catabolic processGO:00467004940.319
rna dependent dna replicationGO:0006278250.303
nucleic acid phosphodiester bond hydrolysisGO:00903051940.288
regulation of mitotic cell cycleGO:00073461070.286
cell cycle dna replicationGO:0044786360.281
telomere maintenance via telomere lengtheningGO:0010833220.278
regulation of protein kinase activityGO:0045859670.273
dna geometric changeGO:0032392430.273
negative regulation of chromosome organizationGO:2001251390.272
regulation of protein modification processGO:00313991100.265
Yeast
regulation of cell cycle g2 m phase transitionGO:190274980.251
cellular nitrogen compound catabolic processGO:00442704940.248
aromatic compound catabolic processGO:00194394910.242
regulation of meiosisGO:0040020420.240
Yeast
regulation of dna dependent dna replicationGO:0090329370.238
Yeast
negative regulation of cellular biosynthetic processGO:00313273120.223
Yeast
dna strand elongationGO:0022616290.222
macromolecule catabolic processGO:00090573830.214
nucleoside phosphate metabolic processGO:00067534580.211
sister chromatid segregationGO:0000819930.210
regulation of catalytic activityGO:00507903070.206
nucleoside phosphate biosynthetic processGO:1901293800.202
cell divisionGO:00513012050.202
Yeast
regulation of mitotic cell cycle phase transitionGO:1901990680.201
dna topological changeGO:0006265100.184
nucleotide excision repairGO:0006289500.170
regulation of protein serine threonine kinase activityGO:0071900410.167
meiotic cell cycleGO:00513212720.164
Yeast
protein complex assemblyGO:00064613020.161
negative regulation of biosynthetic processGO:00098903120.160
Yeast
nucleotide metabolic processGO:00091174530.157
mitotic nuclear divisionGO:00070671310.157
regulation of nuclear divisionGO:00517831030.156
Yeast
anatomical structure homeostasisGO:0060249740.154
dna duplex unwindingGO:0032508420.150
dna dependent dna replication maintenance of fidelityGO:0045005140.148
Yeast
mitotic dna integrity checkpointGO:0044774180.147
regulation of biological qualityGO:00650083910.145
organonitrogen compound catabolic processGO:19015654040.144
single organism catabolic processGO:00447126190.140
regulation of protein phosphorylationGO:0001932750.135
Yeast
regulation of kinase activityGO:0043549710.134
negative regulation of macromolecule biosynthetic processGO:00105582910.126
Yeast
nucleobase containing small molecule metabolic processGO:00550864910.126
cell cycle phase transitionGO:00447701440.123
regulation of protein metabolic processGO:00512462370.121
Yeast
cell differentiationGO:00301541610.121
organophosphate biosynthetic processGO:00904071820.120
sexual reproductionGO:00199532160.120
negative regulation of cellular component organizationGO:00511291090.119
Yeast
regulation of meiotic cell cycleGO:0051445430.116
Yeast
glycosyl compound catabolic processGO:19016583350.115
glycosyl compound metabolic processGO:19016573980.115
dna catabolic processGO:0006308420.109
signal transductionGO:00071652080.109
Yeast
purine containing compound catabolic processGO:00725233320.107
nucleobase containing compound catabolic processGO:00346554790.107
mitotic recombinationGO:0006312550.106
regulation of phosphorylationGO:0042325860.104
negative regulation of cellular macromolecule biosynthetic processGO:20001132890.101
Yeast
mitotic dna damage checkpointGO:0044773110.101
negative regulation of sister chromatid segregationGO:0033046240.099
homeostatic processGO:00425922270.097
positive regulation of protein modification processGO:0031401490.096
Yeast
single organism reproductive processGO:00447021590.096
regulation of response to stressGO:0080134570.093
negative regulation of macromolecule metabolic processGO:00106053750.091
Yeast
dna strand elongation involved in dna replicationGO:0006271260.091
regulation of cell divisionGO:00513021130.087
Yeast
multi organism reproductive processGO:00447032160.086
conjugationGO:00007461070.086
regulation of meiosis iGO:0060631140.085
telomere maintenance via recombinationGO:0000722320.084
regulation of molecular functionGO:00650093200.082
regulation of transferase activityGO:0051338830.082
negative regulation of cell divisionGO:0051782660.081
Yeast
cellular ketone metabolic processGO:0042180630.079
double strand break repair via nonhomologous end joiningGO:0006303270.079
ribonucleotide metabolic processGO:00092593770.077
positive regulation of protein metabolic processGO:0051247930.076
Yeast
regulation of mitosisGO:0007088650.075
purine nucleotide metabolic processGO:00061633760.073
positive regulation of phosphorylationGO:0042327330.072
Yeast
g1 s transition of mitotic cell cycleGO:0000082640.070
purine ribonucleotide metabolic processGO:00091503720.069
positive regulation of phosphorus metabolic processGO:00105621470.068
Yeast
nucleoside metabolic processGO:00091163940.068
negative regulation of mitotic sister chromatid separationGO:2000816230.067
signalingGO:00230522080.067
Yeast
carbohydrate derivative metabolic processGO:19011355490.067
replication fork protectionGO:004847860.067
Yeast
intracellular signal transductionGO:00355561120.066
meiotic chromosome segregationGO:0045132310.065
positive regulation of cell cycle processGO:0090068310.065
cytoskeleton organizationGO:00070102300.064
positive regulation of catalytic activityGO:00430851780.064
nucleoside triphosphate catabolic processGO:00091433290.063
purine ribonucleoside catabolic processGO:00461303300.063
regulation of dna dependent dna replication initiationGO:0030174210.062
reproduction of a single celled organismGO:00325051910.062
Yeast
negative regulation of transcription dna templatedGO:00458922580.061
nucleoside catabolic processGO:00091643350.061
mitotic sister chromatid separationGO:0051306260.059
telomere cappingGO:0016233100.058
ribonucleoside metabolic processGO:00091193890.058
purine nucleoside catabolic processGO:00061523300.057
organophosphate metabolic processGO:00196375970.056
protein dna complex assemblyGO:00650041050.056
regulation of dna recombinationGO:0000018240.056
purine nucleoside triphosphate catabolic processGO:00091463290.055
purine ribonucleoside metabolic processGO:00461283800.054
negative regulation of cell cycle g2 m phase transitionGO:190275050.054
conjugation with cellular fusionGO:00007471060.053
negative regulation of catabolic processGO:0009895430.053
lagging strand elongationGO:0006273100.052
regulation of phosphate metabolic processGO:00192202300.052
metaphase anaphase transition of cell cycleGO:0044784280.051
dna biosynthetic processGO:0071897330.050
negative regulation of cellular catabolic processGO:0031330430.050
cellular developmental processGO:00488691910.049
Yeast
single organism developmental processGO:00447672580.049
Yeast
mitotic spindle assembly checkpointGO:0007094230.048
regulation of cellular response to stressGO:0080135500.048
cellular response to chemical stimulusGO:00708873150.047
Yeast
ribonucleoside catabolic processGO:00424543320.047
nucleoside phosphate catabolic processGO:19012923310.047
regulation of metaphase anaphase transition of cell cycleGO:1902099270.047
protein dna complex subunit organizationGO:00718241530.046
dna double strand break processingGO:000072980.045
g2 m transition of mitotic cell cycleGO:0000086380.045
response to organic cyclic compoundGO:001407010.044
establishment of nucleus localizationGO:0040023220.044
ribonucleotide catabolic processGO:00092613270.043
response to abiotic stimulusGO:00096281590.043
Yeast
negative regulation of organelle organizationGO:00106391030.042
Yeast
negative regulation of protein metabolic processGO:0051248850.042
ribose phosphate metabolic processGO:00196933840.042
reproductive process in single celled organismGO:00224131450.042
nuclear dna replicationGO:0033260270.041
mitotic spindle checkpointGO:0071174340.041
purine nucleoside metabolic processGO:00422783800.041
mitotic cytokinesisGO:0000281580.041
chromosome separationGO:0051304330.041
hexose metabolic processGO:0019318780.040
Yeast
regulation of phosphorus metabolic processGO:00511742300.040
cell cycle g2 m phase transitionGO:0044839390.039
regulation of response to stimulusGO:00485831570.038
negative regulation of dna dependent dna replicationGO:200010480.038
Yeast
meiotic mismatch repairGO:000071090.037
purine ribonucleoside triphosphate catabolic processGO:00092073270.037
purine ribonucleotide catabolic processGO:00091543270.036
regulation of transcription from rna polymerase ii promoterGO:00063573940.035
mating type switchingGO:0007533280.035
purine nucleotide catabolic processGO:00061953280.035
negative regulation of mitotic sister chromatid segregationGO:0033048240.034
nucleotide catabolic processGO:00091663300.034
cellular amino acid metabolic processGO:00065202250.034
double strand break repair via single strand annealingGO:004500270.034
gene conversion at mating type locusGO:0007534110.034
meiotic recombination checkpointGO:005159890.034
Yeast
chromatin assembly or disassemblyGO:0006333600.033
cellular amine metabolic processGO:0044106510.033
negative regulation of gene expressionGO:00106293120.033
negative regulation of cellular protein metabolic processGO:0032269850.033
heteroduplex formationGO:003049190.033
cell communicationGO:00071543450.033
Yeast
negative regulation of nucleic acid templated transcriptionGO:19035072600.032
carbohydrate derivative catabolic processGO:19011363390.032
ribonucleoside triphosphate catabolic processGO:00092033270.032
regulation of mitotic sister chromatid segregationGO:0033047300.032
negative regulation of gene expression epigeneticGO:00458141470.031
negative regulation of rna metabolic processGO:00512532620.031
oxidation reduction processGO:00551143530.030
multi organism processGO:00517042330.030
negative regulation of phosphate metabolic processGO:0045936490.030
positive regulation of dna metabolic processGO:0051054260.030
microtubule based processGO:00070171170.029
purine ribonucleoside triphosphate metabolic processGO:00092053540.028
double strand break repair via synthesis dependent strand annealingGO:0045003120.028
developmental processGO:00325022610.028
Yeast
regulation of intracellular signal transductionGO:1902531780.028
developmental process involved in reproductionGO:00030061590.028
regulation of mitotic metaphase anaphase transitionGO:0030071270.028
establishment of mitotic sister chromatid cohesionGO:0034087150.028
negative regulation of rna biosynthetic processGO:19026792600.028
metaphase anaphase transition of mitotic cell cycleGO:0007091280.028
posttranscriptional regulation of gene expressionGO:00106081150.028
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051270.028
positive regulation of cellular protein metabolic processGO:0032270890.027
Yeast
positive regulation of protein phosphorylationGO:0001934280.027
Yeast
regulation of cellular amine metabolic processGO:0033238210.027
amine metabolic processGO:0009308510.027
peptidyl amino acid modificationGO:00181931160.027
dna catabolic process endonucleolyticGO:0000737310.026
establishment of organelle localizationGO:0051656960.026
purine nucleoside triphosphate metabolic processGO:00091443560.025
vesicle mediated transportGO:00161923350.025
purine containing compound metabolic processGO:00725214000.025
microtubule cytoskeleton organizationGO:00002261090.025
positive regulation of cellular component organizationGO:00511301160.024
maintenance of dna repeat elementsGO:0043570200.024
negative regulation of nuclear divisionGO:0051784620.023
Yeast
organophosphate catabolic processGO:00464343380.023
spindle organizationGO:0007051370.023
ribonucleoside triphosphate metabolic processGO:00091993560.023
dna replication checkpointGO:000007690.022
nucleoside triphosphate metabolic processGO:00091413640.022
response to uvGO:000941140.021
cell buddingGO:0007114480.021
Yeast
regulation of cellular amino acid metabolic processGO:0006521160.021
regulation of multi organism processGO:0043900200.021
meiotic dna double strand break processingGO:000070650.020
sex determinationGO:0007530320.020
cell wall organizationGO:00715551460.020
nucleoside monophosphate metabolic processGO:00091232670.020
meiotic dna double strand break formationGO:0042138120.020
positive regulation of intracellular protein transportGO:009031630.020
base excision repairGO:0006284140.020
response to osmotic stressGO:0006970830.020
Yeast
mismatch repairGO:0006298140.019
positive regulation of programmed cell deathGO:004306830.019
apoptotic processGO:0006915300.019
meiotic cell cycle checkpointGO:0033313100.019
Yeast
regulation of cellular catabolic processGO:00313291950.019
chromatin silencingGO:00063421470.019
positive regulation of cell deathGO:001094230.018
organonitrogen compound biosynthetic processGO:19015663140.018
negative regulation of metaphase anaphase transition of cell cycleGO:1902100230.018
positive regulation of protein modification by small protein conjugation or removalGO:1903322120.018
dephosphorylationGO:00163111270.018
regulation of signal transductionGO:00099661140.018
mating type determinationGO:0007531320.018
regulation of hydrolase activityGO:00513361330.018
cellular response to organic substanceGO:00713101590.018
regulation of homeostatic processGO:0032844190.018
organelle assemblyGO:00709251180.017
histone phosphorylationGO:001657230.017
ubiquitin dependent protein catabolic processGO:00065111810.017
regulation of cyclin dependent protein serine threonine kinase activityGO:0000079190.017
purine ribonucleoside monophosphate metabolic processGO:00091672620.017
positive regulation of cytoplasmic transportGO:190365140.017
negative regulation of nitrogen compound metabolic processGO:00511723000.017
Yeast
positive regulation of molecular functionGO:00440931850.017
positive regulation of macromolecule metabolic processGO:00106043940.017
Yeast
fungal type cell wall organizationGO:00315051450.016
negative regulation of phosphorus metabolic processGO:0010563490.016
sphingolipid biosynthetic processGO:0030148290.016
anatomical structure morphogenesisGO:00096531600.016
Yeast
regulation of proteolysis involved in cellular protein catabolic processGO:1903050360.016
purine ribonucleoside monophosphate catabolic processGO:00091692240.016
atp catabolic processGO:00062002240.016
chromatin assemblyGO:0031497350.016
positive regulation of nitrogen compound metabolic processGO:00511734120.016
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434300.016
negative regulation of catalytic activityGO:0043086600.015
response to organic substanceGO:00100331820.015
response to chemicalGO:00422213900.015
Yeast
gene conversionGO:0035822140.015
cellular response to osmotic stressGO:0071470500.015
Yeast
synapsisGO:0007129190.015
purine nucleoside monophosphate catabolic processGO:00091282240.015
ribonucleoside monophosphate metabolic processGO:00091612650.015
synaptonemal complex assemblyGO:0007130120.015
mitotic spindle organizationGO:0007052300.015
positive regulation of apoptotic processGO:004306530.014
response to starvationGO:0042594960.014
cellular macromolecule catabolic processGO:00442653630.014
cytoskeleton dependent cytokinesisGO:0061640650.014
regulation of dna repairGO:0006282140.014
peptidyl lysine acetylationGO:0018394520.014
ribonucleoside monophosphate catabolic processGO:00091582240.014
purine nucleoside monophosphate metabolic processGO:00091262620.013
dna catabolic process exonucleolyticGO:0000738190.013
growthGO:00400071570.013
Yeast
nucleotide biosynthetic processGO:0009165790.013
negative regulation of proteasomal protein catabolic processGO:1901799250.013
negative regulation of exit from mitosisGO:0001100160.013
endocytosisGO:0006897900.013
positive regulation of catabolic processGO:00098961350.013
regulation of protein modification by small protein conjugation or removalGO:1903320290.013
positive regulation of nuclear divisionGO:005178590.013
nucleoside monophosphate catabolic processGO:00091252240.013
negative regulation of cellular carbohydrate metabolic processGO:0010677170.013
actin cytoskeleton organizationGO:00300361000.013
mitotic chromosome condensationGO:0007076110.012
regulation of protein catabolic processGO:0042176400.012
protein modification by small protein conjugationGO:00324461440.012
g2 dna damage checkpointGO:003157210.012
oxoacid metabolic processGO:00434363510.012
positive regulation of dna replicationGO:0045740110.012
protein dephosphorylationGO:0006470400.012
negative regulation of protein catabolic processGO:0042177270.012
positive regulation of spindle pole body separationGO:001069670.011
negative regulation of proteolysisGO:0045861330.011
negative regulation of g2 m transition of mitotic cell cycleGO:001097250.011
atp metabolic processGO:00460342510.011
membrane lipid biosynthetic processGO:0046467540.011
positive regulation of protein kinase activityGO:0045860220.011
intracellular protein transportGO:00068863190.011
carbohydrate derivative biosynthetic processGO:19011371810.011
regulation of response to extracellular stimulusGO:0032104200.011
negative regulation of mitosisGO:0045839390.011
regulation of transcription involved in g1 s transition of mitotic cell cycleGO:0000083270.011
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145350.011
regulation of cell communicationGO:00106461240.011
sporulation resulting in formation of a cellular sporeGO:00304351290.010
monosaccharide metabolic processGO:0005996830.010
Yeast
regulation of chromosome segregationGO:0051983440.010
cellular component morphogenesisGO:0032989970.010
Yeast
glucose metabolic processGO:0006006650.010
Yeast

RAD53 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.015