Saccharomyces cerevisiae

156 known processes

POL2 (YNL262W)

Pol2p

(Aliases: DUN2)

POL2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna replicationGO:00062601470.988
dna dependent dna replicationGO:00062611150.986
dna repairGO:00062812360.950
dna strand elongation involved in dna replicationGO:0006271260.922
double strand break repairGO:00063021050.842
cellular response to dna damage stimulusGO:00069742870.822
error prone translesion synthesisGO:0042276110.796
aromatic compound catabolic processGO:00194394910.794
postreplication repairGO:0006301240.776
dna strand elongationGO:0022616290.766
dna biosynthetic processGO:0071897330.719
nucleobase containing compound catabolic processGO:00346554790.697
negative regulation of macromolecule metabolic processGO:00106053750.623
heterocycle catabolic processGO:00467004940.542
rna catabolic processGO:00064011180.516
gene silencingGO:00164581510.503
cellular macromolecule catabolic processGO:00442653630.449
negative regulation of nucleobase containing compound metabolic processGO:00459342950.438
cellular nitrogen compound catabolic processGO:00442704940.401
lagging strand elongationGO:0006273100.380
organic cyclic compound catabolic processGO:19013614990.378
macromolecule catabolic processGO:00090573830.336
negative regulation of biosynthetic processGO:00098903120.324
cell differentiationGO:00301541610.262
negative regulation of gene expression epigeneticGO:00458141470.233
single organism signalingGO:00447002080.231
cellular developmental processGO:00488691910.195
negative regulation of macromolecule biosynthetic processGO:00105582910.194
translesion synthesisGO:0019985160.167
regulation of mitotic cell cycleGO:00073461070.158
developmental processGO:00325022610.155
Worm
negative regulation of cellular biosynthetic processGO:00313273120.152
single organism reproductive processGO:00447021590.151
Worm
chromatin silencing at telomereGO:0006348840.149
single organism developmental processGO:00447672580.147
Worm
rna dependent dna replicationGO:0006278250.146
negative regulation of nucleic acid templated transcriptionGO:19035072600.144
establishment of protein localizationGO:00451843670.139
single organism catabolic processGO:00447126190.137
negative regulation of transcription dna templatedGO:00458922580.136
organophosphate metabolic processGO:00196375970.134
negative regulation of cellular metabolic processGO:00313244070.130
regulation of dna metabolic processGO:00510521000.130
dna dependent dna replication maintenance of fidelityGO:0045005140.127
homeostatic processGO:00425922270.123
negative regulation of rna biosynthetic processGO:19026792600.122
reproductive process in single celled organismGO:00224131450.121
protein localization to organelleGO:00333653370.116
dna replication initiationGO:0006270480.111
dna conformation changeGO:0071103980.108
protein acylationGO:0043543660.107
regulation of gene expression epigeneticGO:00400291470.106
developmental process involved in reproductionGO:00030061590.104
Worm
intracellular protein transportGO:00068863190.104
nucleobase containing small molecule metabolic processGO:00550864910.100
dna recombinationGO:00063101720.096
endosomal transportGO:0016197860.096
glycosyl compound catabolic processGO:19016583350.091
cell wall organization or biogenesisGO:00715541900.091
double strand break repair via break induced replicationGO:0000727250.089
negative regulation of nitrogen compound metabolic processGO:00511723000.088
negative regulation of cellular macromolecule biosynthetic processGO:20001132890.088
negative regulation of cell cycle phase transitionGO:1901988590.086
negative regulation of rna metabolic processGO:00512532620.085
regulation of catalytic activityGO:00507903070.085
protein import into nucleusGO:0006606550.083
ribonucleotide catabolic processGO:00092613270.082
organophosphate catabolic processGO:00464343380.082
snorna metabolic processGO:0016074400.081
ribonucleoside catabolic processGO:00424543320.081
covalent chromatin modificationGO:00165691190.080
reproduction of a single celled organismGO:00325051910.080
purine nucleoside triphosphate catabolic processGO:00091463290.080
reproductive processGO:00224142480.077
Worm
nucleoside phosphate metabolic processGO:00067534580.077
peptidyl lysine modificationGO:0018205770.076
agingGO:0007568710.075
base excision repairGO:0006284140.075
mitotic cell cycle checkpointGO:0007093560.073
protein transportGO:00150313450.072
peptidyl lysine acetylationGO:0018394520.070
meiotic cell cycle processGO:19030462290.070
nucleotide metabolic processGO:00091174530.069
nucleotide catabolic processGO:00091663300.067
cell fate commitmentGO:0045165320.066
mating type switchingGO:0007533280.065
trna metabolic processGO:00063991510.065
chemical homeostasisGO:00488781370.064
negative regulation of mitotic cell cycleGO:0045930630.063
purine ribonucleoside triphosphate metabolic processGO:00092053540.061
purine nucleotide metabolic processGO:00061633760.061
mitotic cell cycle processGO:19030472940.060
signalingGO:00230522080.060
nucleoside metabolic processGO:00091163940.060
regulation of cellular component organizationGO:00511283340.058
recombinational repairGO:0000725640.058
single organism cellular localizationGO:19025803750.057
regulation of biological qualityGO:00650083910.057
establishment of protein localization to organelleGO:00725942780.057
translationGO:00064122300.057
nucleocytoplasmic transportGO:00069131630.057
purine nucleoside triphosphate metabolic processGO:00091443560.056
histone acetylationGO:0016573510.056
cell wall organizationGO:00715551460.056
chromatin silencingGO:00063421470.056
nucleoside triphosphate catabolic processGO:00091433290.055
chromatin silencing at silent mating type cassetteGO:0030466530.055
protein importGO:00170381220.055
purine ribonucleotide catabolic processGO:00091543270.054
nucleus localizationGO:0051647220.054
ribonucleoside triphosphate metabolic processGO:00091993560.051
purine ribonucleoside metabolic processGO:00461283800.051
regulation of cell cycle processGO:00105641500.050
regulation of cell cycle phase transitionGO:1901987700.049
regulation of cellular component biogenesisGO:00440871120.048
atp metabolic processGO:00460342510.048
protein localization to nucleusGO:0034504740.048
cell communicationGO:00071543450.047
meiotic cell cycleGO:00513212720.047
dna replication removal of rna primerGO:004313750.047
peptidyl amino acid modificationGO:00181931160.046
internal protein amino acid acetylationGO:0006475520.046
regulation of mitotic cell cycle phase transitionGO:1901990680.046
organonitrogen compound biosynthetic processGO:19015663140.046
meiotic mismatch repairGO:000071090.045
negative regulation of mitotic cell cycle phase transitionGO:1901991570.044
mitotic chromosome condensationGO:0007076110.044
positive regulation of cell cycleGO:0045787320.043
double strand break repair via homologous recombinationGO:0000724540.043
carbohydrate derivative catabolic processGO:19011363390.041
guanosine containing compound metabolic processGO:19010681110.040
purine ribonucleoside catabolic processGO:00461303300.040
nucleoside triphosphate metabolic processGO:00091413640.039
protein targeting to nucleusGO:0044744570.039
single organism nuclear importGO:1902593560.039
chromosome segregationGO:00070591590.038
telomere maintenance via telomeraseGO:0007004210.038
nucleoside phosphate catabolic processGO:19012923310.038
cellular response to abiotic stimulusGO:0071214620.035
glycerophospholipid metabolic processGO:0006650980.035
telomere organizationGO:0032200750.034
negative regulation of cell cycle processGO:0010948860.034
positive regulation of molecular functionGO:00440931850.034
double strand break repair via nonhomologous end joiningGO:0006303270.034
cell cycle phase transitionGO:00447701440.034
carbohydrate derivative metabolic processGO:19011355490.033
chromatin modificationGO:00165682000.033
external encapsulating structure organizationGO:00452291460.033
organelle localizationGO:00516401280.033
gtp metabolic processGO:00460391070.032
protein targetingGO:00066052720.032
negative regulation of dna metabolic processGO:0051053360.031
organonitrogen compound catabolic processGO:19015654040.031
regulation of molecular functionGO:00650093200.031
snrna metabolic processGO:0016073250.030
nucleoside catabolic processGO:00091643350.030
dna replication okazaki fragment processingGO:003356770.029
negative regulation of cellular protein metabolic processGO:0032269850.029
regulation of nucleotide catabolic processGO:00308111060.029
ncrna catabolic processGO:0034661330.029
cellular homeostasisGO:00197251380.029
regulation of protein metabolic processGO:00512462370.028
mitotic recombinationGO:0006312550.027
cell divisionGO:00513012050.027
regulation of hydrolase activityGO:00513361330.027
chromatin silencing at rdnaGO:0000183320.027
glycosyl compound metabolic processGO:19016573980.027
glycerolipid metabolic processGO:00464861080.026
negative regulation of gene expressionGO:00106293120.026
regulation of purine nucleotide catabolic processGO:00331211060.026
mitotic dna integrity checkpointGO:0044774180.025
mitotic nuclear divisionGO:00070671310.025
ribonucleotide metabolic processGO:00092593770.025
phospholipid metabolic processGO:00066441250.025
purine nucleoside catabolic processGO:00061523300.025
dna unwinding involved in dna replicationGO:0006268130.025
dna geometric changeGO:0032392430.024
establishment of nucleus localizationGO:0040023220.024
atp catabolic processGO:00062002240.024
regulation of nucleoside metabolic processGO:00091181060.024
rna polyadenylationGO:0043631260.024
intracellular signal transductionGO:00355561120.023
mitotic sister chromatid cohesionGO:0007064380.023
positive regulation of catalytic activityGO:00430851780.023
multi organism reproductive processGO:00447032160.023
generation of precursor metabolites and energyGO:00060911470.023
posttranscriptional regulation of gene expressionGO:00106081150.023
heterochromatin organization involved in chromatin silencingGO:007086880.023
purine nucleotide catabolic processGO:00061953280.022
nucleoside monophosphate metabolic processGO:00091232670.022
dna duplex unwindingGO:0032508420.022
guanosine containing compound catabolic processGO:19010691090.022
organophosphate biosynthetic processGO:00904071820.021
nucleotide excision repairGO:0006289500.021
regulation of protein complex assemblyGO:0043254770.021
response to uvGO:000941140.021
dna integrity checkpointGO:0031570410.021
multi organism processGO:00517042330.021
glycerolipid biosynthetic processGO:0045017710.021
cell agingGO:0007569700.020
regulation of signalingGO:00230511190.020
ribonucleoside metabolic processGO:00091193890.020
protein acetylationGO:0006473590.020
ribose phosphate metabolic processGO:00196933840.020
purine nucleoside metabolic processGO:00422783800.020
mitochondrion organizationGO:00070052610.020
histone h3 acetylationGO:004396650.020
phospholipid biosynthetic processGO:0008654890.019
non recombinational repairGO:0000726330.019
cell cycle checkpointGO:0000075820.019
response to external stimulusGO:00096051580.019
regulation of protein modification processGO:00313991100.019
regulation of cellular catabolic processGO:00313291950.019
negative regulation of molecular functionGO:0044092680.019
sporulation resulting in formation of a cellular sporeGO:00304351290.019
sex determinationGO:0007530320.019
protein dna complex subunit organizationGO:00718241530.019
mismatch repairGO:0006298140.019
regulation of organelle organizationGO:00330432430.018
oxidation reduction processGO:00551143530.018
purine ribonucleoside monophosphate catabolic processGO:00091692240.018
ncrna processingGO:00344703300.018
purine containing compound catabolic processGO:00725233320.018
regulation of cell cycleGO:00517261950.018
regulation of catabolic processGO:00098941990.017
mitotic cell cycle phase transitionGO:00447721410.017
cellular ion homeostasisGO:00068731120.017
nuclear importGO:0051170570.017
regulation of signal transductionGO:00099661140.017
dna catabolic process endonucleolyticGO:0000737310.017
cellular chemical homeostasisGO:00550821230.017
maintenance of dna repeat elementsGO:0043570200.017
anatomical structure morphogenesisGO:00096531600.016
regulation of cellular protein metabolic processGO:00322682320.016
regulation of dna dependent dna replicationGO:0090329370.016
nuclear migrationGO:0007097220.016
protein export from nucleusGO:0006611170.016
vesicle mediated transportGO:00161923350.016
lipid metabolic processGO:00066292690.016
protein complex biogenesisGO:00702713140.016
cellular response to starvationGO:0009267900.016
ribonucleoside triphosphate catabolic processGO:00092033270.016
modification dependent macromolecule catabolic processGO:00436322030.016
alcohol metabolic processGO:00060661120.016
pre replicative complex assembly involved in nuclear cell cycle dna replicationGO:0006267200.015
response to organic cyclic compoundGO:001407010.015
positive regulation of hydrolase activityGO:00513451120.015
nucleic acid phosphodiester bond hydrolysisGO:00903051940.015
regulation of purine nucleotide metabolic processGO:19005421090.015
dna topological changeGO:0006265100.015
cellular lipid metabolic processGO:00442552290.015
negative regulation of protein metabolic processGO:0051248850.015
mating type determinationGO:0007531320.014
nuclear mrna surveillanceGO:0071028220.014
rrna catabolic processGO:0016075310.014
meiotic nuclear divisionGO:00071261630.014
protein complex assemblyGO:00064613020.014
meiosis iGO:0007127920.014
pre replicative complex assemblyGO:0036388200.014
positive regulation of catabolic processGO:00098961350.014
snorna processingGO:0043144340.014
internal peptidyl lysine acetylationGO:0018393520.014
purine ribonucleoside monophosphate metabolic processGO:00091672620.014
regulation of mrna splicing via spliceosomeGO:004802430.014
telomere cappingGO:0016233100.014
sister chromatid cohesionGO:0007062490.014
carbohydrate derivative biosynthetic processGO:19011371810.013
negative regulation of dna replicationGO:0008156150.013
mitotic cell cycleGO:00002783060.013
small molecule catabolic processGO:0044282880.013
cation homeostasisGO:00550801050.013
glycerophospholipid biosynthetic processGO:0046474680.013
positive regulation of cellular component organizationGO:00511301160.013
response to osmotic stressGO:0006970830.013
regulation of dna recombinationGO:0000018240.013
fungal type cell wall organizationGO:00315051450.013
purine ribonucleotide metabolic processGO:00091503720.013
negative regulation of protein modification processGO:0031400370.013
vesicle organizationGO:0016050680.013
chromatin organizationGO:00063252420.013
gene conversionGO:0035822140.013
dna packagingGO:0006323550.013
sexual reproductionGO:00199532160.012
purine ribonucleoside triphosphate catabolic processGO:00092073270.012
cell developmentGO:00484681070.012
regulation of dna replicationGO:0006275510.012
regulation of nucleotide metabolic processGO:00061401100.012
g1 s transition of mitotic cell cycleGO:0000082640.012
Human
regulation of cell differentiationGO:0045595120.012
carboxylic acid metabolic processGO:00197523380.012
negative regulation of cell cycleGO:0045786910.012
cellular response to external stimulusGO:00714961500.012
dephosphorylationGO:00163111270.012
positive regulation of protein modification processGO:0031401490.012
regulation of gtp catabolic processGO:0033124840.012
metal ion homeostasisGO:0055065790.012
mitochondrial genome maintenanceGO:0000002400.011
positive regulation of macromolecule biosynthetic processGO:00105573250.011
cell surface receptor signaling pathwayGO:0007166380.011
filamentous growth of a population of unicellular organismsGO:00441821090.011
vacuolar transportGO:00070341450.011
regulation of translationGO:0006417890.011
positive regulation of gene expressionGO:00106283210.011
pre replicative complex assembly involved in cell cycle dna replicationGO:1902299200.011
cell growthGO:0016049890.011
positive regulation of dna metabolic processGO:0051054260.011
endocytosisGO:0006897900.011
positive regulation of cytoplasmic transportGO:190365140.011
heterochromatin organizationGO:0070828110.011
regulation of ras gtpase activityGO:0032318410.011
positive regulation of cellular catabolic processGO:00313311280.011
filamentous growthGO:00304471240.011
positive regulation of macromolecule metabolic processGO:00106043940.010
cut catabolic processGO:0071034120.010
ascospore formationGO:00304371070.010
fatty acid metabolic processGO:0006631510.010
telomere maintenance via telomere lengtheningGO:0010833220.010
ion homeostasisGO:00508011180.010
negative regulation of phosphorus metabolic processGO:0010563490.010
mitotic sister chromatid segregationGO:0000070850.010
cellular biogenic amine metabolic processGO:0006576370.010
fungal type cell wall organization or biogenesisGO:00718521690.010

POL2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.041
cancerDOID:16200.018
Human
organ system cancerDOID:005068600.018
Human
disease of cellular proliferationDOID:1456600.018
Human