Saccharomyces cerevisiae

48 known processes

TIM50 (YPL063W)

Tim50p

TIM50 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
establishment of protein localization to mitochondrionGO:0072655631.000
protein targeting to mitochondrionGO:0006626560.999
protein transmembrane transportGO:0071806820.998
protein import into mitochondrial matrixGO:0030150200.996
protein localization to mitochondrionGO:0070585630.994
mitochondrial transportGO:0006839760.992
protein importGO:00170381220.978
establishment of protein localization to organelleGO:00725942780.977
protein targetingGO:00066052720.971
intracellular protein transportGO:00068863190.950
transmembrane transportGO:00550853490.947
mitochondrion organizationGO:00070052610.944
establishment of protein localizationGO:00451843670.930
protein transportGO:00150313450.925
single organism cellular localizationGO:19025803750.853
protein localization to organelleGO:00333653370.848
intracellular protein transmembrane transportGO:0065002800.847
intracellular protein transmembrane importGO:0044743670.807
mitochondrial membrane organizationGO:0007006480.242
inner mitochondrial membrane organizationGO:0007007260.230
rrna metabolic processGO:00160722440.123
establishment of protein localization to membraneGO:0090150990.121
protein complex biogenesisGO:00702713140.119
ribosomal small subunit biogenesisGO:00422741240.108
establishment of protein localization to mitochondrial membraneGO:0090151200.103
positive regulation of cellular biosynthetic processGO:00313283360.086
cellular response to chemical stimulusGO:00708873150.079
ncrna processingGO:00344703300.072
trna transportGO:0051031190.071
positive regulation of macromolecule metabolic processGO:00106043940.069
protein complex assemblyGO:00064613020.065
nucleobase containing compound transportGO:00159311240.064
cellular developmental processGO:00488691910.061
single organism membrane organizationGO:00448022750.059
single organism developmental processGO:00447672580.059
ribonucleoprotein complex assemblyGO:00226181430.059
positive regulation of biosynthetic processGO:00098913360.058
regulation of cellular component organizationGO:00511283340.056
meiotic cell cycle processGO:19030462290.053
protein localization to membraneGO:00726571020.052
membrane organizationGO:00610242760.052
nucleoside monophosphate metabolic processGO:00091232670.049
chromatin organizationGO:00063252420.049
cell communicationGO:00071543450.049
nucleic acid transportGO:0050657940.048
regulation of biological qualityGO:00650083910.047
negative regulation of nucleobase containing compound metabolic processGO:00459342950.047
vesicle mediated transportGO:00161923350.046
anatomical structure morphogenesisGO:00096531600.044
positive regulation of gene expressionGO:00106283210.044
developmental processGO:00325022610.043
response to chemicalGO:00422213900.043
negative regulation of nucleic acid templated transcriptionGO:19035072600.042
cellular response to organic substanceGO:00713101590.042
homeostatic processGO:00425922270.042
ribonucleoprotein complex subunit organizationGO:00718261520.042
rrna processingGO:00063642270.041
translationGO:00064122300.041
positive regulation of nitrogen compound metabolic processGO:00511734120.039
translational initiationGO:0006413560.038
negative regulation of cellular macromolecule biosynthetic processGO:20001132890.038
negative regulation of cellular metabolic processGO:00313244070.038
cellular response to extracellular stimulusGO:00316681500.037
nitrogen compound transportGO:00717052120.037
cellular component morphogenesisGO:0032989970.037
growthGO:00400071570.036
response to external stimulusGO:00096051580.036
mitotic cell cycle processGO:19030472940.035
positive regulation of macromolecule biosynthetic processGO:00105573250.035
single organism catabolic processGO:00447126190.035
dna replicationGO:00062601470.033
phospholipid metabolic processGO:00066441250.033
negative regulation of rna biosynthetic processGO:19026792600.033
carbohydrate derivative metabolic processGO:19011355490.033
regulation of protein metabolic processGO:00512462370.032
generation of precursor metabolites and energyGO:00060911470.032
cellular protein complex assemblyGO:00436232090.032
purine ribonucleotide metabolic processGO:00091503720.032
ribosome biogenesisGO:00422543350.031
covalent chromatin modificationGO:00165691190.031
regulation of dna metabolic processGO:00510521000.031
aerobic respirationGO:0009060550.031
cellular response to nutrient levelsGO:00316691440.031
purine ribonucleoside triphosphate metabolic processGO:00092053540.031
purine nucleoside monophosphate metabolic processGO:00091262620.030
cellular amide metabolic processGO:0043603590.030
rna transportGO:0050658920.030
organic acid metabolic processGO:00060823520.030
anatomical structure developmentGO:00488561600.029
protein import into mitochondrial inner membraneGO:0045039110.029
response to organic substanceGO:00100331820.029
nucleoside phosphate metabolic processGO:00067534580.028
nucleotide metabolic processGO:00091174530.028
protein localization to endoplasmic reticulumGO:0070972470.028
regulation of protein complex assemblyGO:0043254770.028
purine nucleoside triphosphate metabolic processGO:00091443560.028
cellular response to external stimulusGO:00714961500.028
chromatin modificationGO:00165682000.028
nuclear exportGO:00511681240.028
positive regulation of nucleobase containing compound metabolic processGO:00459354090.027
mitotic cell cycleGO:00002783060.027
oxidation reduction processGO:00551143530.027
dna packagingGO:0006323550.027
protein phosphorylationGO:00064681970.027
response to extracellular stimulusGO:00099911560.027
organelle fissionGO:00482852720.027
regulation of cellular component biogenesisGO:00440871120.027
lipid transportGO:0006869580.027
response to nutrient levelsGO:00316671500.026
purine ribonucleoside monophosphate metabolic processGO:00091672620.026
rna localizationGO:00064031120.026
organelle localizationGO:00516401280.026
nucleobase containing compound catabolic processGO:00346554790.026
negative regulation of cellular biosynthetic processGO:00313273120.026
regulation of translationGO:0006417890.025
rna methylationGO:0001510390.025
mitotic cell cycle phase transitionGO:00447721410.025
cofactor metabolic processGO:00511861260.025
purine nucleotide metabolic processGO:00061633760.025
sexual reproductionGO:00199532160.025
purine containing compound metabolic processGO:00725214000.024
meiotic cell cycleGO:00513212720.024
nucleosome organizationGO:0034728630.024
protein modification by small protein conjugationGO:00324461440.024
cellular homeostasisGO:00197251380.024
negative regulation of nitrogen compound metabolic processGO:00511723000.024
negative regulation of rna metabolic processGO:00512532620.024
regulation of catabolic processGO:00098941990.024
ribosomal subunit export from nucleusGO:0000054460.024
autophagyGO:00069141060.024
cofactor biosynthetic processGO:0051188800.024
cellular respirationGO:0045333820.024
ribonucleoside monophosphate metabolic processGO:00091612650.023
ribose phosphate metabolic processGO:00196933840.023
lipid localizationGO:0010876600.023
dna dependent dna replicationGO:00062611150.023
ribonucleoside triphosphate metabolic processGO:00091993560.023
regulation of cellular catabolic processGO:00313291950.023
ascospore formationGO:00304371070.022
maturation of ssu rrnaGO:00304901050.022
cellular lipid metabolic processGO:00442552290.022
nucleocytoplasmic transportGO:00069131630.022
maturation of ssu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000462960.022
lipid metabolic processGO:00066292690.022
nucleobase containing small molecule metabolic processGO:00550864910.022
regulation of dna replicationGO:0006275510.022
regulation of organelle organizationGO:00330432430.022
negative regulation of biosynthetic processGO:00098903120.022
establishment of organelle localizationGO:0051656960.021
ribosome localizationGO:0033750460.021
water soluble vitamin biosynthetic processGO:0042364380.021
dephosphorylationGO:00163111270.021
atp catabolic processGO:00062002240.021
phospholipid biosynthetic processGO:0008654890.021
ribonucleotide metabolic processGO:00092593770.021
establishment of rna localizationGO:0051236920.021
positive regulation of transcription dna templatedGO:00458932860.021
nucleoside phosphate catabolic processGO:19012923310.021
reproduction of a single celled organismGO:00325051910.021
cell developmentGO:00484681070.021
multi organism reproductive processGO:00447032160.021
rrna modificationGO:0000154190.021
signal transductionGO:00071652080.020
purine ribonucleoside triphosphate catabolic processGO:00092073270.020
cellular macromolecule catabolic processGO:00442653630.020
sporulationGO:00439341320.020
regulation of localizationGO:00328791270.020
organophosphate catabolic processGO:00464343380.020
negative regulation of transcription dna templatedGO:00458922580.019
response to organic cyclic compoundGO:001407010.019
negative regulation of gene expressionGO:00106293120.019
regulation of phosphorus metabolic processGO:00511742300.019
chemical homeostasisGO:00488781370.019
response to abiotic stimulusGO:00096281590.019
protein dna complex subunit organizationGO:00718241530.019
purine ribonucleoside catabolic processGO:00461303300.019
organonitrogen compound biosynthetic processGO:19015663140.019
regulation of catalytic activityGO:00507903070.019
carboxylic acid metabolic processGO:00197523380.019
rrna containing ribonucleoprotein complex export from nucleusGO:0071428460.019
sporulation resulting in formation of a cellular sporeGO:00304351290.018
golgi to plasma membrane transportGO:0006893330.018
establishment or maintenance of cell polarityGO:0007163960.018
organophosphate metabolic processGO:00196375970.018
vacuolar transportGO:00070341450.018
regulation of mitotic cell cycleGO:00073461070.018
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000466800.018
negative regulation of macromolecule metabolic processGO:00106053750.018
reproductive process in single celled organismGO:00224131450.018
rna splicing via transesterification reactions with guanosine as nucleophileGO:0000376100.018
organic anion transportGO:00157111140.018
cell growthGO:0016049890.018
coenzyme metabolic processGO:00067321040.018
protein foldingGO:0006457940.017
histone lysine methylationGO:0034968260.017
ribonucleoside catabolic processGO:00424543320.017
trna metabolic processGO:00063991510.017
positive regulation of catabolic processGO:00098961350.017
negative regulation of cellular component organizationGO:00511291090.017
trna aminoacylation for protein translationGO:0006418320.017
reproductive processGO:00224142480.017
ribonucleotide catabolic processGO:00092613270.017
negative regulation of phosphorus metabolic processGO:0010563490.017
developmental process involved in reproductionGO:00030061590.017
organelle fusionGO:0048284850.017
establishment of ribosome localizationGO:0033753460.017
golgi vesicle transportGO:00481931880.017
posttranscriptional regulation of gene expressionGO:00106081150.017
glycosyl compound metabolic processGO:19016573980.017
histone modificationGO:00165701190.017
organelle assemblyGO:00709251180.017
regulation of response to stimulusGO:00485831570.017
single organism signalingGO:00447002080.017
glycerophospholipid metabolic processGO:0006650980.017
peptide metabolic processGO:0006518280.017
ribosomal large subunit assemblyGO:0000027350.017
positive regulation of translationGO:0045727340.017
post golgi vesicle mediated transportGO:0006892720.017
cellular nitrogen compound catabolic processGO:00442704940.016
regulation of cell cycleGO:00517261950.016
organonitrogen compound catabolic processGO:19015654040.016
histone methylationGO:0016571280.016
positive regulation of rna metabolic processGO:00512542940.016
sterol transportGO:0015918240.016
regulation of molecular functionGO:00650093200.016
peptidyl lysine acetylationGO:0018394520.016
rrna export from nucleusGO:0006407180.016
dna strand elongationGO:0022616290.016
ribosome assemblyGO:0042255570.016
fungal type cell wall organization or biogenesisGO:00718521690.016
ion transportGO:00068112740.016
positive regulation of cellular catabolic processGO:00313311280.016
nucleoside triphosphate metabolic processGO:00091413640.016
cellular response to oxidative stressGO:0034599940.016
purine nucleoside monophosphate catabolic processGO:00091282240.016
mitotic nuclear divisionGO:00070671310.015
regulation of metal ion transportGO:001095920.015
trna export from nucleusGO:0006409160.015
negative regulation of macromolecule biosynthetic processGO:00105582910.015
anion transportGO:00068201450.015
dna conformation changeGO:0071103980.015
nucleus organizationGO:0006997620.015
ribonucleoprotein complex localizationGO:0071166460.015
dna catabolic processGO:0006308420.015
single organism reproductive processGO:00447021590.015
cellular amine metabolic processGO:0044106510.015
meiotic chromosome segregationGO:0045132310.015
energy derivation by oxidation of organic compoundsGO:00159801250.015
rna phosphodiester bond hydrolysis exonucleolyticGO:0090503290.015
cellular cation homeostasisGO:00300031000.015
peptidyl lysine modificationGO:0018205770.015
phospholipid transportGO:0015914230.015
regulation of cellular protein metabolic processGO:00322682320.015
rrna transportGO:0051029180.015
trna methylationGO:0030488210.015
glycosyl compound catabolic processGO:19016583350.015
signalingGO:00230522080.015
maturation of 5 8s rrnaGO:0000460800.015
growth of unicellular organism as a thread of attached cellsGO:00707831050.015
macromolecule glycosylationGO:0043413570.015
conjugationGO:00007461070.015
regulation of cellular ketone metabolic processGO:0010565420.014
regulation of dna dependent dna replicationGO:0090329370.014
nucleoside metabolic processGO:00091163940.014
negative regulation of cell cycle phase transitionGO:1901988590.014
oxoacid metabolic processGO:00434363510.014
water soluble vitamin metabolic processGO:0006767410.014
sexual sporulationGO:00342931130.014
nucleoside catabolic processGO:00091643350.014
mrna modificationGO:0016556100.014
protein modification by small protein conjugation or removalGO:00706471720.014
ribonucleoside monophosphate catabolic processGO:00091582240.014
regulation of phosphate metabolic processGO:00192202300.014
membrane fusionGO:0061025730.014
positive regulation of intracellular protein transportGO:009031630.014
positive regulation of nucleotide metabolic processGO:00459811010.014
protein acylationGO:0043543660.014
proteolysisGO:00065082680.014
cellular chemical homeostasisGO:00550821230.014
cell cycle checkpointGO:0000075820.014
oxidoreduction coenzyme metabolic processGO:0006733580.014
cell differentiationGO:00301541610.014
conjugation with cellular fusionGO:00007471060.014
glycoprotein biosynthetic processGO:0009101610.014
monocarboxylic acid metabolic processGO:00327871220.014
amine metabolic processGO:0009308510.014
purine ribonucleoside metabolic processGO:00461283800.014
purine ribonucleotide catabolic processGO:00091543270.013
positive regulation of protein metabolic processGO:0051247930.013
regulation of lipid metabolic processGO:0019216450.013
rna splicingGO:00083801310.013
trna processingGO:00080331010.013
cell cycle g2 m phase transitionGO:0044839390.013
response to pheromoneGO:0019236920.013
cation transportGO:00068121660.013
dna strand elongation involved in dna replicationGO:0006271260.013
purine nucleoside catabolic processGO:00061523300.013
rrna pseudouridine synthesisGO:003111840.013
vitamin biosynthetic processGO:0009110380.013
cellular amino acid biosynthetic processGO:00086521180.013
heterocycle catabolic processGO:00467004940.013
ascospore wall assemblyGO:0030476520.013
regulation of mitochondrion organizationGO:0010821200.013
endomembrane system organizationGO:0010256740.013
spore wall assemblyGO:0042244520.013
dna recombinationGO:00063101720.013
protein targeting to erGO:0045047390.013
organic cyclic compound catabolic processGO:19013614990.013
positive regulation of nucleic acid templated transcriptionGO:19035082860.013
chromatin assemblyGO:0031497350.013
telomere organizationGO:0032200750.013
regulation of nucleoside metabolic processGO:00091181060.013
protein localization to nucleusGO:0034504740.013
cellular response to dna damage stimulusGO:00069742870.013
response to starvationGO:0042594960.013
glycerolipid metabolic processGO:00464861080.013
maturation of lsu rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna GO:0000463330.013
purine nucleotide catabolic processGO:00061953280.013
atp metabolic processGO:00460342510.013
sexual sporulation resulting in formation of a cellular sporeGO:00439351130.013
nucleoside monophosphate catabolic processGO:00091252240.013
protein dna complex assemblyGO:00650041050.013
anatomical structure homeostasisGO:0060249740.013
organic acid transportGO:0015849770.013
cleavage involved in rrna processingGO:0000469690.012
maturation of lsu rrnaGO:0000470390.012
atp synthesis coupled electron transportGO:0042773250.012
protein methylationGO:0006479480.012
ribonucleoprotein complex export from nucleusGO:0071426460.012
positive regulation of rna biosynthetic processGO:19026802860.012
response to topologically incorrect proteinGO:0035966380.012
carboxylic acid transportGO:0046942740.012
peptidyl amino acid modificationGO:00181931160.012
protein glycosylationGO:0006486570.012
chromatin assembly or disassemblyGO:0006333600.012
positive regulation of organelle organizationGO:0010638850.012
protein processingGO:0016485640.012
transcription initiation from rna polymerase ii promoterGO:0006367550.012
macromolecule methylationGO:0043414850.012
filamentous growth of a population of unicellular organismsGO:00441821090.012
maintenance of locationGO:0051235660.012
positive regulation of purine nucleotide metabolic processGO:19005441000.012
regulation of dna dependent dna replication initiationGO:0030174210.012
protein localization to vacuoleGO:0072665920.012
mitotic recombinationGO:0006312550.012
gene silencingGO:00164581510.012
vitamin metabolic processGO:0006766410.012
intracellular signal transductionGO:00355561120.012
pseudohyphal growthGO:0007124750.012
positive regulation of nucleoside metabolic processGO:0045979970.012
rna 5 end processingGO:0000966330.012
amino acid transportGO:0006865450.012
anatomical structure formation involved in morphogenesisGO:00486461360.011
organophosphate ester transportGO:0015748450.011
multi organism processGO:00517042330.011
endosomal transportGO:0016197860.011
carbohydrate metabolic processGO:00059752520.011
protein alkylationGO:0008213480.011
aromatic compound catabolic processGO:00194394910.011
rrna methylationGO:0031167130.011
mitotic sister chromatid cohesionGO:0007064380.011
purine nucleoside triphosphate catabolic processGO:00091463290.011
iron ion homeostasisGO:0055072340.011
regulation of cell growthGO:0001558290.011
nuclear divisionGO:00002802630.011
regulation of transportGO:0051049850.011
trna wobble base modificationGO:0002097270.011
regulation of transmembrane transporter activityGO:002289810.011
positive regulation of cytoplasmic transportGO:190365140.011
pyruvate metabolic processGO:0006090370.011
negative regulation of cellular protein metabolic processGO:0032269850.011
positive regulation of programmed cell deathGO:004306830.011
filamentous growthGO:00304471240.011
modification dependent macromolecule catabolic processGO:00436322030.011
positive regulation of intracellular transportGO:003238840.011
peroxisome organizationGO:0007031680.011
cell cycle phase transitionGO:00447701440.011
rna phosphodiester bond hydrolysisGO:00905011120.011
response to uvGO:000941140.011
histone acetylationGO:0016573510.011
endoplasmic reticulum organizationGO:0007029300.011
internal peptidyl lysine acetylationGO:0018393520.011
chromosome segregationGO:00070591590.011
mitochondrial respiratory chain complex iii biogenesisGO:0097033110.011
alcohol biosynthetic processGO:0046165750.011
positive regulation of cellular protein metabolic processGO:0032270890.011
protein targeting to vacuoleGO:0006623910.011
fungal type cell wall organizationGO:00315051450.011
ubiquitin dependent protein catabolic processGO:00065111810.011
protein n linked glycosylationGO:0006487340.011
g2 m transition of mitotic cell cycleGO:0000086380.011
rna export from nucleusGO:0006405880.011
regulation of cell communicationGO:00106461240.011
guanosine containing compound catabolic processGO:19010691090.011
cell divisionGO:00513012050.011
organelle inheritanceGO:0048308510.011
cytoplasmic translational initiationGO:000218370.011
carbohydrate derivative catabolic processGO:19011363390.011
positive regulation of sequence specific dna binding transcription factor activityGO:005109120.011
establishment of protein localization to vacuoleGO:0072666910.011
protein export from nucleusGO:0006611170.010
negative regulation of dna metabolic processGO:0051053360.010
positive regulation of protein complex assemblyGO:0031334390.010
cellular response to pheromoneGO:0071444880.010
regulation of mitotic cell cycle phase transitionGO:1901990680.010
spore wall biogenesisGO:0070590520.010
respiratory electron transport chainGO:0022904250.010
negative regulation of cell cycleGO:0045786910.010
rna 3 end processingGO:0031123880.010
sister chromatid cohesionGO:0007062490.010
cellular metal ion homeostasisGO:0006875780.010
protein targeting to membraneGO:0006612520.010
regulation of cell divisionGO:00513021130.010
protein insertion into membraneGO:0051205130.010
regulation of reproductive processGO:2000241240.010
ribosomal small subunit assemblyGO:0000028150.010
cytoplasmic translationGO:0002181650.010
purine containing compound catabolic processGO:00725233320.010
amino acid activationGO:0043038350.010
telomere maintenanceGO:0000723740.010
atp dependent chromatin remodelingGO:0043044360.010
dna replication initiationGO:0006270480.010
golgi to vacuole transportGO:0006896230.010
regulation of purine nucleotide metabolic processGO:19005421090.010
negative regulation of dna replicationGO:0008156150.010

TIM50 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
nervous system diseaseDOID:86300.014
hematopoietic system diseaseDOID:7400.011
bone marrow diseaseDOID:496100.011
immune system diseaseDOID:291400.011
congenital hypoplastic anemiaDOID:134200.010
diamond blackfan anemiaDOID:133900.010
anemiaDOID:235500.010
aplastic anemiaDOID:1244900.010