Saccharomyces cerevisiae

112 known processes

SIR2 (YDL042C)

Sir2p

(Aliases: MAR1)

SIR2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of gene expression epigeneticGO:00400291470.999
chromatin silencingGO:00063421470.998
gene silencingGO:00164581510.997
negative regulation of transcription dna templatedGO:00458922580.997
negative regulation of rna metabolic processGO:00512532620.995
negative regulation of gene expression epigeneticGO:00458141470.993
negative regulation of cellular macromolecule biosynthetic processGO:20001132890.993
negative regulation of rna biosynthetic processGO:19026792600.989
negative regulation of macromolecule metabolic processGO:00106053750.989
negative regulation of nucleic acid templated transcriptionGO:19035072600.989
negative regulation of nucleobase containing compound metabolic processGO:00459342950.987
negative regulation of macromolecule biosynthetic processGO:00105582910.982
negative regulation of gene expressionGO:00106293120.980
negative regulation of nitrogen compound metabolic processGO:00511723000.980
chromatin modificationGO:00165682000.978
negative regulation of biosynthetic processGO:00098903120.977
negative regulation of cellular metabolic processGO:00313244070.977
chromatin organizationGO:00063252420.926
double strand break repairGO:00063021050.887
negative regulation of cellular biosynthetic processGO:00313273120.857
cellular response to dna damage stimulusGO:00069742870.771
dna conformation changeGO:0071103980.729
dna packagingGO:0006323550.723
cell agingGO:0007569700.695
agingGO:0007568710.681
chromatin silencing at telomereGO:0006348840.591
replicative cell agingGO:0001302460.554
dna repairGO:00062812360.499
regulation of chromatin silencingGO:0031935390.381
chromatin silencing at silent mating type cassetteGO:0030466530.372
cellular response to chemical stimulusGO:00708873150.361
nucleobase containing compound catabolic processGO:00346554790.314
single organism developmental processGO:00447672580.292
covalent chromatin modificationGO:00165691190.271
signalingGO:00230522080.270
regulation of cell divisionGO:00513021130.231
dna replication initiationGO:0006270480.228
response to chemicalGO:00422213900.223
response to organic substanceGO:00100331820.223
heterocycle catabolic processGO:00467004940.221
dna recombinationGO:00063101720.209
recombinational repairGO:0000725640.209
histone modificationGO:00165701190.202
meiotic cell cycle processGO:19030462290.199
negative regulation of gene silencingGO:0060969270.175
response to oxidative stressGO:0006979990.160
mitotic cell cycle processGO:19030472940.151
cellular nitrogen compound catabolic processGO:00442704940.147
developmental processGO:00325022610.145
macromolecule catabolic processGO:00090573830.142
regulation of cellular component organizationGO:00511283340.140
multi organism processGO:00517042330.130
dna replicationGO:00062601470.129
nuclear divisionGO:00002802630.126
aromatic compound catabolic processGO:00194394910.124
cellular amino acid metabolic processGO:00065202250.121
regulation of biological qualityGO:00650083910.121
cell communicationGO:00071543450.118
negative regulation of chromatin silencingGO:0031936250.117
cellular response to oxidative stressGO:0034599940.117
regulation of vesicle mediated transportGO:0060627390.116
organic cyclic compound catabolic processGO:19013614990.114
regulation of dna metabolic processGO:00510521000.112
carboxylic acid metabolic processGO:00197523380.112
Yeast
nucleus organizationGO:0006997620.111
regulation of dna dependent dna replication initiationGO:0030174210.103
single organism catabolic processGO:00447126190.101
protein localization to organelleGO:00333653370.101
chromatin assemblyGO:0031497350.098
organelle fissionGO:00482852720.094
chromatin silencing at rdnaGO:0000183320.089
regulation of transportGO:0051049850.081
regulation of cell cycle processGO:00105641500.078
homeostatic processGO:00425922270.077
non recombinational repairGO:0000726330.075
positive regulation of biosynthetic processGO:00098913360.074
phosphorylationGO:00163102910.068
cellular developmental processGO:00488691910.068
regulation of localizationGO:00328791270.067
glycosyl compound metabolic processGO:19016573980.067
double strand break repair via homologous recombinationGO:0000724540.067
cellular response to organic substanceGO:00713101590.065
anatomical structure homeostasisGO:0060249740.063
regulation of cell communicationGO:00106461240.061
rrna transcriptionGO:0009303310.059
response to nutrient levelsGO:00316671500.057
regulation of organelle organizationGO:00330432430.057
regulation of dna replicationGO:0006275510.055
cellular lipid metabolic processGO:00442552290.054
Yeast
negative regulation of dna metabolic processGO:0051053360.053
cell surface receptor signaling pathwayGO:0007166380.053
negative regulation of transcription from rna polymerase ii promoterGO:00001221370.050
cellular response to heatGO:0034605530.050
mitotic cell cycleGO:00002783060.050
reproductive processGO:00224142480.049
chromatin assembly or disassemblyGO:0006333600.048
establishment or maintenance of cell polarityGO:0007163960.048
cell cycle phase transitionGO:00447701440.048
regulation of gene silencingGO:0060968410.048
single organism signalingGO:00447002080.047
organic acid metabolic processGO:00060823520.047
Yeast
dna damage checkpointGO:0000077290.045
signal transductionGO:00071652080.044
sexual reproductionGO:00199532160.042
negative regulation of cell divisionGO:0051782660.042
dna dependent dna replicationGO:00062611150.041
meiotic nuclear divisionGO:00071261630.041
multi organism reproductive processGO:00447032160.040
single organism reproductive processGO:00447021590.040
negative regulation of cell communicationGO:0010648330.039
positive regulation of macromolecule metabolic processGO:00106043940.038
lipid localizationGO:0010876600.038
nucleoside catabolic processGO:00091643350.038
response to heatGO:0009408690.038
proteolysisGO:00065082680.037
response to oxygen containing compoundGO:1901700610.037
small molecule catabolic processGO:0044282880.036
cell differentiationGO:00301541610.036
organonitrogen compound catabolic processGO:19015654040.035
regulation of transcription from rna polymerase ii promoterGO:00063573940.035
positive regulation of gene expression epigeneticGO:0045815250.035
growthGO:00400071570.034
multi organism cellular processGO:00447641200.034
macromolecule methylationGO:0043414850.034
negative regulation of organelle organizationGO:00106391030.034
cellular chemical homeostasisGO:00550821230.032
regulation of transcription by chromatin organizationGO:0034401190.032
protein modification by small protein conjugation or removalGO:00706471720.031
nucleotide metabolic processGO:00091174530.031
protein localization to chromosomeGO:0034502280.029
mitotic cell cycle phase transitionGO:00447721410.029
nucleoside metabolic processGO:00091163940.029
autophagyGO:00069141060.029
regulation of catabolic processGO:00098941990.028
purine containing compound metabolic processGO:00725214000.028
cellular response to starvationGO:0009267900.028
organophosphate metabolic processGO:00196375970.027
carbohydrate derivative metabolic processGO:19011355490.027
nucleic acid phosphodiester bond hydrolysisGO:00903051940.027
mrna metabolic processGO:00160712690.026
chromatin remodelingGO:0006338800.025
chromosome condensationGO:0030261190.024
cellular response to extracellular stimulusGO:00316681500.024
positive regulation of nitrogen compound metabolic processGO:00511734120.023
rdna condensationGO:007055090.022
oxoacid metabolic processGO:00434363510.022
Yeast
nucleobase containing small molecule metabolic processGO:00550864910.022
nuclear transcribed mrna catabolic processGO:0000956890.022
sex determinationGO:0007530320.022
glycosyl compound catabolic processGO:19016583350.022
positive regulation of macromolecule biosynthetic processGO:00105573250.022
dna templated transcription terminationGO:0006353420.021
dephosphorylationGO:00163111270.021
g1 s transition of mitotic cell cycleGO:0000082640.021
cellular response to external stimulusGO:00714961500.021
negative regulation of cellular component organizationGO:00511291090.021
reproduction of a single celled organismGO:00325051910.020
response to organic cyclic compoundGO:001407010.020
protein phosphorylationGO:00064681970.020
double strand break repair via nonhomologous end joiningGO:0006303270.019
negative regulation of cell cycle processGO:0010948860.018
regulation of response to stressGO:0080134570.018
protein ubiquitinationGO:00165671180.018
negative regulation of mitotic cell cycleGO:0045930630.018
organophosphate catabolic processGO:00464343380.018
purine containing compound catabolic processGO:00725233320.018
regulation of multi organism processGO:0043900200.017
single organism cellular localizationGO:19025803750.017
response to uvGO:000941140.017
regulation of cellular response to stressGO:0080135500.017
response to external stimulusGO:00096051580.017
response to abiotic stimulusGO:00096281590.016
regulation of cell growthGO:0001558290.016
conjugationGO:00007461070.016
telomere maintenance via telomeraseGO:0007004210.016
lipid metabolic processGO:00066292690.016
Yeast
cell divisionGO:00513012050.016
cellular ketone metabolic processGO:0042180630.016
carbohydrate derivative catabolic processGO:19011363390.015
cellular protein catabolic processGO:00442572130.015
snrna processingGO:0016180170.015
telomere organizationGO:0032200750.015
regulation of cell cycle phase transitionGO:1901987700.015
regulation of catalytic activityGO:00507903070.015
cellular amino acid catabolic processGO:0009063480.015
cell fate commitmentGO:0045165320.015
ribose phosphate metabolic processGO:00196933840.014
regulation of dna dependent dna replicationGO:0090329370.014
mating type switchingGO:0007533280.014
conjugation with cellular fusionGO:00007471060.014
meiotic cell cycleGO:00513212720.014
trna metabolic processGO:00063991510.014
response to inorganic substanceGO:0010035470.013
establishment of cell polarityGO:0030010640.013
carbohydrate metabolic processGO:00059752520.013
positive regulation of cellular biosynthetic processGO:00313283360.013
negative regulation of cell cycle phase transitionGO:1901988590.013
peptidyl lysine modificationGO:0018205770.013
regulation of mitotic cell cycle phase transitionGO:1901990680.012
protein dna complex subunit organizationGO:00718241530.012
ribonucleotide metabolic processGO:00092593770.012
positive regulation of catabolic processGO:00098961350.012
negative regulation of cell cycleGO:0045786910.012
mrna catabolic processGO:0006402930.012
mating type determinationGO:0007531320.012
regulation of response to stimulusGO:00485831570.012
regulation of meiotic cell cycleGO:0051445430.012
peptidyl lysine acetylationGO:0018394520.011
regulation of chromatin silencing at telomereGO:0031938270.011
protein complex assemblyGO:00064613020.011
positive regulation of rna metabolic processGO:00512542940.011
rna catabolic processGO:00064011180.011
regulation of signal transductionGO:00099661140.011
response to temperature stimulusGO:0009266740.011
dna catabolic processGO:0006308420.011
regulation of cellular ketone metabolic processGO:0010565420.011
regulation of protein metabolic processGO:00512462370.011
positive regulation of dna metabolic processGO:0051054260.011
regulation of molecular functionGO:00650093200.010
telomere maintenance via telomere lengtheningGO:0010833220.010
peptidyl amino acid modificationGO:00181931160.010
double strand break repair via break induced replicationGO:0000727250.010
cellular ion homeostasisGO:00068731120.010
positive regulation of nucleic acid templated transcriptionGO:19035082860.010
internal protein amino acid acetylationGO:0006475520.010
transcription dependent tethering of rna polymerase ii gene dna at nuclear peripheryGO:0000972190.010
response to endogenous stimulusGO:0009719260.010

SIR2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.015