IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

81 known processes

CAD1 (YDR423C)

Cad1p

(Aliases: YAP2)

Entrez: 852033
SGD: S000002831
UniProtKB: P24813

Process Predictions
Disease Predictions

CAD1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
regulation of biological quality	GO:0065008	391	0.150
response to chemical	GO:0042221	390	0.146
cation transport	GO:0006812	166	0.131
signaling	GO:0023052	208	0.113
cellular amino acid metabolic process	GO:0006520	225	0.104
cell communication	GO:0007154	345	0.104
macromolecule catabolic process	GO:0009057	383	0.095
response to oxygen containing compound	GO:1901700	61	0.086
establishment of protein localization	GO:0045184	367	0.086
single organism cellular localization	GO:1902580	375	0.084
aromatic compound catabolic process	GO:0019439	491	0.082
carboxylic acid catabolic process	GO:0046395	71	0.081
protein modification by small protein conjugation	GO:0032446	144	0.077
vacuolar transport	GO:0007034	145	0.074
cell wall organization	GO:0071555	146	0.074
response to oxidative stress	GO:0006979	99	0.074
response to endogenous stimulus	GO:0009719	26	0.073
small molecule catabolic process	GO:0044282	88	0.072
cellular macromolecule catabolic process	GO:0044265	363	0.070
ribonucleoprotein complex subunit organization	GO:0071826	152	0.066
fungal type cell wall organization or biogenesis	GO:0071852	169	0.066
organic acid metabolic process	GO:0006082	352	0.065
carboxylic acid metabolic process	GO:0019752	338	0.063
endosomal transport	GO:0016197	86	0.062
single organism catabolic process	GO:0044712	619	0.062
external encapsulating structure organization	GO:0045229	146	0.059
response to organic substance	GO:0010033	182	0.058
organelle assembly	GO:0070925	118	0.057
meiotic cell cycle	GO:0051321	272	0.056
heterocycle catabolic process	GO:0046700	494	0.054
protein modification by small protein conjugation or removal	GO:0070647	172	0.053
protein targeting to membrane	GO:0006612	52	0.053
response to organonitrogen compound	GO:0010243	18	0.053
regulation of cellular component organization	GO:0051128	334	0.052
cellular nitrogen compound catabolic process	GO:0044270	494	0.052
single organism developmental process	GO:0044767	258	0.051
alpha amino acid metabolic process	GO:1901605	124	0.051
glycerophospholipid metabolic process	GO:0006650	98	0.049
response to organic cyclic compound	GO:0014070	1	0.049
ion transmembrane transport	GO:0034220	200	0.048
organelle localization	GO:0051640	128	0.048
organophosphate metabolic process	GO:0019637	597	0.046
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.046
cellular ketone metabolic process	GO:0042180	63	0.046
cell division	GO:0051301	205	0.044
protein transport	GO:0015031	345	0.044
developmental process	GO:0032502	261	0.043
protein localization to membrane	GO:0072657	102	0.043
cell wall organization or biogenesis	GO:0071554	190	0.043
ribonucleoprotein complex assembly	GO:0022618	143	0.042
cofactor biosynthetic process	GO:0051188	80	0.041
phosphorylation	GO:0016310	291	0.041
response to reactive oxygen species	GO:0000302	22	0.041
response to nutrient levels	GO:0031667	150	0.041
regulation of localization	GO:0032879	127	0.041
negative regulation of cellular metabolic process	GO:0031324	407	0.040
cellular response to chemical stimulus	GO:0070887	315	0.039
late endosome to vacuole transport via multivesicular body sorting pathway	GO:0032511	26	0.039
intracellular protein transport	GO:0006886	319	0.039
cellular response to oxidative stress	GO:0034599	94	0.039
reciprocal dna recombination	GO:0035825	54	0.039
ion transport	GO:0006811	274	0.038
organic cyclic compound catabolic process	GO:1901361	499	0.038
cellular response to external stimulus	GO:0071496	150	0.036
regulation of cellular localization	GO:0060341	50	0.036
cofactor metabolic process	GO:0051186	126	0.036
positive regulation of biosynthetic process	GO:0009891	336	0.036
oxoacid metabolic process	GO:0043436	351	0.036
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.035
cellular amino acid biosynthetic process	GO:0008652	118	0.035
positive regulation of cellular biosynthetic process	GO:0031328	336	0.035
regulation of protein metabolic process	GO:0051246	237	0.034
homeostatic process	GO:0042592	227	0.034
fungal type cell wall organization	GO:0031505	145	0.034
regulation of cell communication	GO:0010646	124	0.033
regulation of molecular function	GO:0065009	320	0.032
multi organism process	GO:0051704	233	0.032
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.032
nuclear transcribed mrna catabolic process	GO:0000956	89	0.032
maintenance of location	GO:0051235	66	0.032
membrane organization	GO:0061024	276	0.031
single organism signaling	GO:0044700	208	0.031
regulation of mitosis	GO:0007088	65	0.031
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.031
reciprocal meiotic recombination	GO:0007131	54	0.031
regulation of response to stimulus	GO:0048583	157	0.030
regulation of phosphorus metabolic process	GO:0051174	230	0.030
regulation of anatomical structure size	GO:0090066	50	0.030
positive regulation of rna metabolic process	GO:0051254	294	0.030
rrna processing	GO:0006364	227	0.029
anatomical structure morphogenesis	GO:0009653	160	0.029
organelle fission	GO:0048285	272	0.029
rna catabolic process	GO:0006401	118	0.029
meiosis i	GO:0007127	92	0.029
protein catabolic process	GO:0030163	221	0.028
dna replication	GO:0006260	147	0.028
signal transduction	GO:0007165	208	0.027
small molecule biosynthetic process	GO:0044283	258	0.027
ion homeostasis	GO:0050801	118	0.027
nuclear division	GO:0000280	263	0.027
regulation of receptor mediated endocytosis	GO:0048259	4	0.027
positive regulation of intracellular transport	GO:0032388	4	0.027
lipid transport	GO:0006869	58	0.026
endosome transport via multivesicular body sorting pathway	GO:0032509	27	0.026
peptidyl amino acid modification	GO:0018193	116	0.026
anion transmembrane transport	GO:0098656	79	0.026
cellular carbohydrate metabolic process	GO:0044262	135	0.026
positive regulation of programmed cell death	GO:0043068	3	0.025
negative regulation of mitosis	GO:0045839	39	0.025
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.025
regulation of cell cycle process	GO:0010564	150	0.025
regulation of nuclear division	GO:0051783	103	0.025
carbohydrate catabolic process	GO:0016052	77	0.025
regulation of cellular catabolic process	GO:0031329	195	0.025
ncrna processing	GO:0034470	330	0.025
protein localization to organelle	GO:0033365	337	0.025
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.024
nucleoside phosphate metabolic process	GO:0006753	458	0.024
positive regulation of apoptotic process	GO:0043065	3	0.024
response to external stimulus	GO:0009605	158	0.024
positive regulation of fatty acid oxidation	GO:0046321	3	0.024
dephosphorylation	GO:0016311	127	0.023
phosphatidylinositol metabolic process	GO:0046488	62	0.023
cellular protein catabolic process	GO:0044257	213	0.023
cellular lipid metabolic process	GO:0044255	229	0.023
regulation of cellular protein metabolic process	GO:0032268	232	0.023
organonitrogen compound catabolic process	GO:1901565	404	0.023
response to abiotic stimulus	GO:0009628	159	0.023
nucleotide metabolic process	GO:0009117	453	0.023
cellular polysaccharide metabolic process	GO:0044264	55	0.023
cellular response to extracellular stimulus	GO:0031668	150	0.023
regulation of dna metabolic process	GO:0051052	100	0.022
negative regulation of protein metabolic process	GO:0051248	85	0.022
ribonucleoside catabolic process	GO:0042454	332	0.022
regulation of cell division	GO:0051302	113	0.022
positive regulation of cytoplasmic transport	GO:1903651	4	0.022
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.022
coenzyme metabolic process	GO:0006732	104	0.022
mitochondrion organization	GO:0007005	261	0.022
carbohydrate metabolic process	GO:0005975	252	0.021
response to extracellular stimulus	GO:0009991	156	0.021
cellular response to dna damage stimulus	GO:0006974	287	0.021
negative regulation of macromolecule metabolic process	GO:0010605	375	0.021
protein phosphorylation	GO:0006468	197	0.021
mitotic cell cycle checkpoint	GO:0007093	56	0.021
golgi vesicle transport	GO:0048193	188	0.021
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.020
protein complex assembly	GO:0006461	302	0.020
cellular response to organic substance	GO:0071310	159	0.020
negative regulation of phosphorus metabolic process	GO:0010563	49	0.020
chemical homeostasis	GO:0048878	137	0.020
positive regulation of cell death	GO:0010942	3	0.020
reproductive process	GO:0022414	248	0.020
regulation of dna replication	GO:0006275	51	0.020
nucleobase containing compound catabolic process	GO:0034655	479	0.020
late endosome to vacuole transport	GO:0045324	42	0.019
cellular response to oxygen containing compound	GO:1901701	43	0.019
rna 3 end processing	GO:0031123	88	0.019
protein ubiquitination	GO:0016567	118	0.019
meiotic cell cycle process	GO:1903046	229	0.019
regulation of phosphate metabolic process	GO:0019220	230	0.019
regulation of cellular component size	GO:0032535	50	0.019
negative regulation of gene expression	GO:0010629	312	0.019
regulation of transferase activity	GO:0051338	83	0.018
purine nucleotide catabolic process	GO:0006195	328	0.018
establishment of protein localization to vacuole	GO:0072666	91	0.018
negative regulation of protein phosphorylation	GO:0001933	24	0.018
carboxylic acid biosynthetic process	GO:0046394	152	0.018
response to osmotic stress	GO:0006970	83	0.018
phospholipid metabolic process	GO:0006644	125	0.018
organonitrogen compound biosynthetic process	GO:1901566	314	0.018
regulation of cell cycle phase transition	GO:1901987	70	0.018
cellular developmental process	GO:0048869	191	0.018
oxidoreduction coenzyme metabolic process	GO:0006733	58	0.018
positive regulation of secretion by cell	GO:1903532	2	0.018
monocarboxylic acid metabolic process	GO:0032787	122	0.018
nuclear transport	GO:0051169	165	0.018
negative regulation of catalytic activity	GO:0043086	60	0.017
regulation of signaling	GO:0023051	119	0.017
protein localization to vacuole	GO:0072665	92	0.017
establishment of protein localization to organelle	GO:0072594	278	0.017
chromosome segregation	GO:0007059	159	0.017
regulation of protein modification process	GO:0031399	110	0.017
regulation of transport	GO:0051049	85	0.017
mitotic cell cycle phase transition	GO:0044772	141	0.017
positive regulation of catalytic activity	GO:0043085	178	0.017
mrna processing	GO:0006397	185	0.017
energy reserve metabolic process	GO:0006112	32	0.017
nucleocytoplasmic transport	GO:0006913	163	0.017
cellular response to nutrient	GO:0031670	50	0.016
glycogen metabolic process	GO:0005977	30	0.016
mrna metabolic process	GO:0016071	269	0.016
cellular response to nutrient levels	GO:0031669	144	0.016
cellular carbohydrate catabolic process	GO:0044275	33	0.016
organic anion transport	GO:0015711	114	0.016
anion transport	GO:0006820	145	0.016
regulation of catalytic activity	GO:0050790	307	0.016
dna recombination	GO:0006310	172	0.016
regulation of cellular component biogenesis	GO:0044087	112	0.016
cellular amino acid catabolic process	GO:0009063	48	0.016
mitotic cell cycle	GO:0000278	306	0.016
negative regulation of organelle organization	GO:0010639	103	0.016
retrograde transport endosome to golgi	GO:0042147	33	0.016
phospholipid biosynthetic process	GO:0008654	89	0.016
cellular protein complex assembly	GO:0043623	209	0.016
sporulation	GO:0043934	132	0.016
positive regulation of transcription dna templated	GO:0045893	286	0.016
organophosphate biosynthetic process	GO:0090407	182	0.016
regulation of cell cycle	GO:0051726	195	0.015
carbohydrate derivative catabolic process	GO:1901136	339	0.015
regulation of intracellular signal transduction	GO:1902531	78	0.015
negative regulation of phosphate metabolic process	GO:0045936	49	0.015
negative regulation of cellular protein metabolic process	GO:0032269	85	0.015
divalent inorganic cation homeostasis	GO:0072507	21	0.015
establishment of organelle localization	GO:0051656	96	0.015
regulation of organelle organization	GO:0033043	243	0.015
positive regulation of molecular function	GO:0044093	185	0.015
regulation of mitotic cell cycle	GO:0007346	107	0.015
cellular homeostasis	GO:0019725	138	0.015
response to nitrogen compound	GO:1901698	18	0.015
growth	GO:0040007	157	0.015
single organism membrane organization	GO:0044802	275	0.015
cell differentiation	GO:0030154	161	0.015
organic acid catabolic process	GO:0016054	71	0.015
regulation of transcription from rna polymerase ii promoter in response to stress	GO:0043618	51	0.015
nucleotide catabolic process	GO:0009166	330	0.015
positive regulation of nucleocytoplasmic transport	GO:0046824	4	0.015
positive regulation of phosphorus metabolic process	GO:0010562	147	0.015
negative regulation of mitotic cell cycle	GO:0045930	63	0.014
regulation of catabolic process	GO:0009894	199	0.014
organic acid biosynthetic process	GO:0016053	152	0.014
vesicle mediated transport	GO:0016192	335	0.014
carbohydrate derivative metabolic process	GO:1901135	549	0.014
lipid biosynthetic process	GO:0008610	170	0.014
spore wall biogenesis	GO:0070590	52	0.014
reproductive process in single celled organism	GO:0022413	145	0.014
mrna catabolic process	GO:0006402	93	0.014
vacuole organization	GO:0007033	75	0.014
nuclear export	GO:0051168	124	0.014
apoptotic process	GO:0006915	30	0.014
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.013
purine ribonucleotide catabolic process	GO:0009154	327	0.013
methylation	GO:0032259	101	0.013
metal ion transport	GO:0030001	75	0.013
response to nutrient	GO:0007584	52	0.013
trna metabolic process	GO:0006399	151	0.013
regulation of protein serine threonine kinase activity	GO:0071900	41	0.013
regulation of protein kinase activity	GO:0045859	67	0.013
positive regulation of macromolecule metabolic process	GO:0010604	394	0.013
ribonucleoside metabolic process	GO:0009119	389	0.013
regulation of hydrolase activity	GO:0051336	133	0.013
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.013
organophosphate ester transport	GO:0015748	45	0.013
regulation of protein complex assembly	GO:0043254	77	0.013
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.013
positive regulation of phosphate metabolic process	GO:0045937	147	0.013
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.013
regulation of fatty acid beta oxidation	GO:0031998	3	0.013
microtubule cytoskeleton organization	GO:0000226	109	0.013
nucleoside catabolic process	GO:0009164	335	0.013
purine ribonucleotide metabolic process	GO:0009150	372	0.013
aging	GO:0007568	71	0.013
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.013
intracellular signal transduction	GO:0035556	112	0.013
response to metal ion	GO:0010038	24	0.013
nucleoside triphosphate catabolic process	GO:0009143	329	0.013
chromatin organization	GO:0006325	242	0.013
atp catabolic process	GO:0006200	224	0.012
microautophagy	GO:0016237	43	0.012
regulation of lipid catabolic process	GO:0050994	4	0.012
response to transition metal nanoparticle	GO:1990267	16	0.012
rrna metabolic process	GO:0016072	244	0.012
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.012
mapk cascade involved in cell wall organization or biogenesis	GO:0000196	9	0.012
positive regulation of hydrolase activity	GO:0051345	112	0.012
translation	GO:0006412	230	0.012
ribosome biogenesis	GO:0042254	335	0.012
purine ribonucleoside metabolic process	GO:0046128	380	0.012
polysaccharide metabolic process	GO:0005976	60	0.012
cellular divalent inorganic cation homeostasis	GO:0072503	21	0.012
organophosphate catabolic process	GO:0046434	338	0.012
spore wall assembly	GO:0042244	52	0.012
cell cycle phase transition	GO:0044770	144	0.012
establishment of protein localization to membrane	GO:0090150	99	0.012
purine containing compound catabolic process	GO:0072523	332	0.012
positive regulation of lipid catabolic process	GO:0050996	4	0.012
cellular cation homeostasis	GO:0030003	100	0.012
organelle inheritance	GO:0048308	51	0.012
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.012
er to golgi vesicle mediated transport	GO:0006888	86	0.012
glycosyl compound metabolic process	GO:1901657	398	0.011
nucleoside triphosphate metabolic process	GO:0009141	364	0.011
response to inorganic substance	GO:0010035	47	0.011
protein targeting	GO:0006605	272	0.011
purine containing compound metabolic process	GO:0072521	400	0.011
conjugation with cellular fusion	GO:0000747	106	0.011
regulation of glucose metabolic process	GO:0010906	27	0.011
negative regulation of cellular component organization	GO:0051129	109	0.011
glycosyl compound catabolic process	GO:1901658	335	0.011
regulation of cell size	GO:0008361	30	0.011
mrna 3 end processing	GO:0031124	54	0.011
negative regulation of transferase activity	GO:0051348	31	0.011
positive regulation of fatty acid beta oxidation	GO:0032000	3	0.011
multi organism reproductive process	GO:0044703	216	0.011
cell surface receptor signaling pathway	GO:0007166	38	0.011
regulation of protein dephosphorylation	GO:0035304	4	0.011
regulation of cellular ketone metabolic process	GO:0010565	42	0.011
response to hypoxia	GO:0001666	4	0.011
amine metabolic process	GO:0009308	51	0.011
regulation of phosphorylation	GO:0042325	86	0.011
cellular glucan metabolic process	GO:0006073	44	0.011
nitrogen compound transport	GO:0071705	212	0.011
intra golgi vesicle mediated transport	GO:0006891	22	0.011
protein targeting to vacuole	GO:0006623	91	0.011
lipid metabolic process	GO:0006629	269	0.011
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.011
nucleoside monophosphate catabolic process	GO:0009125	224	0.011
regulation of kinase activity	GO:0043549	71	0.011
negative regulation of mitotic sister chromatid separation	GO:2000816	23	0.011
purine nucleoside catabolic process	GO:0006152	330	0.011
generation of precursor metabolites and energy	GO:0006091	147	0.011
sexual sporulation	GO:0034293	113	0.011
regulation of microtubule based process	GO:0032886	32	0.011
piecemeal microautophagy of nucleus	GO:0034727	33	0.011
regulation of establishment of protein localization	GO:0070201	17	0.011
transmembrane transport	GO:0055085	349	0.011
purine nucleoside monophosphate catabolic process	GO:0009128	224	0.011
lipid localization	GO:0010876	60	0.011
cellular component disassembly	GO:0022411	86	0.010
cellular response to abiotic stimulus	GO:0071214	62	0.010
reproduction of a single celled organism	GO:0032505	191	0.010
monocarboxylic acid catabolic process	GO:0072329	26	0.010
positive regulation of transport	GO:0051050	32	0.010
biological adhesion	GO:0022610	14	0.010
regulation of ras protein signal transduction	GO:0046578	47	0.010
positive regulation of secretion	GO:0051047	2	0.010
secretion	GO:0046903	50	0.010
ras protein signal transduction	GO:0007265	29	0.010
mapk cascade	GO:0000165	30	0.010
proteasomal protein catabolic process	GO:0010498	141	0.010
response to starvation	GO:0042594	96	0.010
guanosine containing compound metabolic process	GO:1901068	111	0.010
secretion by cell	GO:0032940	50	0.010

CAD1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.032
	nervous system disease	DOID:863	0	0.013

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