IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

60 known processes

SHC1 (YER096W)

Shc1p

SGD: S000000898
Entrez: 856832
UniProtKB: P39000

Process Predictions
Disease Predictions

SHC1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
meiotic cell cycle	GO:0051321	272	0.327
reproductive process in single celled organism	GO:0022413	145	0.327
single organism reproductive process	GO:0044702	159	0.306
ascospore formation	GO:0030437	107	0.294
single organism developmental process	GO:0044767	258	0.271
meiotic cell cycle process	GO:1903046	229	0.260
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.251
reproduction of a single celled organism	GO:0032505	191	0.245
cellular developmental process	GO:0048869	191	0.235
anatomical structure morphogenesis	GO:0009653	160	0.228
multi organism reproductive process	GO:0044703	216	0.225
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.225
developmental process involved in reproduction	GO:0003006	159	0.216
cellular component morphogenesis	GO:0032989	97	0.199
response to chemical	GO:0042221	390	0.187
reproductive process	GO:0022414	248	0.172
sporulation	GO:0043934	132	0.160
carbohydrate metabolic process	GO:0005975	252	0.152
developmental process	GO:0032502	261	0.147
cell differentiation	GO:0030154	161	0.146
anatomical structure development	GO:0048856	160	0.146
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.135
sexual reproduction	GO:0019953	216	0.131
cellular macromolecule catabolic process	GO:0044265	363	0.114
single organism carbohydrate metabolic process	GO:0044723	237	0.112
negative regulation of macromolecule metabolic process	GO:0010605	375	0.112
cell development	GO:0048468	107	0.108
single organism catabolic process	GO:0044712	619	0.095
fungal type cell wall organization or biogenesis	GO:0071852	169	0.090
fungal type cell wall biogenesis	GO:0009272	80	0.086
multi organism process	GO:0051704	233	0.083
negative regulation of cellular biosynthetic process	GO:0031327	312	0.083
macromolecule catabolic process	GO:0009057	383	0.083
negative regulation of rna biosynthetic process	GO:1902679	260	0.081
negative regulation of gene expression	GO:0010629	312	0.080
membrane organization	GO:0061024	276	0.076
regulation of biological quality	GO:0065008	391	0.074
sexual sporulation	GO:0034293	113	0.072
chromatin modification	GO:0016568	200	0.070
oxidation reduction process	GO:0055114	353	0.066
nucleoside metabolic process	GO:0009116	394	0.065
negative regulation of biosynthetic process	GO:0009890	312	0.065
carboxylic acid metabolic process	GO:0019752	338	0.065
cellular lipid metabolic process	GO:0044255	229	0.065
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.063
cell communication	GO:0007154	345	0.060
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.060
fungal type cell wall assembly	GO:0071940	53	0.060
small molecule biosynthetic process	GO:0044283	258	0.060
negative regulation of cellular metabolic process	GO:0031324	407	0.060
cell wall biogenesis	GO:0042546	93	0.059
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.058
hexose metabolic process	GO:0019318	78	0.058
spore wall assembly	GO:0042244	52	0.057
small molecule catabolic process	GO:0044282	88	0.056
regulation of cell cycle	GO:0051726	195	0.056
nucleotide metabolic process	GO:0009117	453	0.055
lipid metabolic process	GO:0006629	269	0.054
lipid biosynthetic process	GO:0008610	170	0.054
cellular response to heat	GO:0034605	53	0.054
organelle fission	GO:0048285	272	0.054
cellular response to extracellular stimulus	GO:0031668	150	0.053
organic acid metabolic process	GO:0006082	352	0.052
single organism cellular localization	GO:1902580	375	0.051
oxoacid metabolic process	GO:0043436	351	0.050
negative regulation of transcription dna templated	GO:0045892	258	0.049
single organism membrane organization	GO:0044802	275	0.049
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.047
response to external stimulus	GO:0009605	158	0.045
carboxylic acid biosynthetic process	GO:0046394	152	0.044
response to temperature stimulus	GO:0009266	74	0.043
purine ribonucleoside metabolic process	GO:0046128	380	0.039
organophosphate metabolic process	GO:0019637	597	0.039
nuclear division	GO:0000280	263	0.037
cellular protein catabolic process	GO:0044257	213	0.037
ribosome biogenesis	GO:0042254	335	0.036
organic acid biosynthetic process	GO:0016053	152	0.036
ascospore wall biogenesis	GO:0070591	52	0.035
cell wall assembly	GO:0070726	54	0.035
ascospore wall assembly	GO:0030476	52	0.034
chromatin organization	GO:0006325	242	0.034
regulation of protein metabolic process	GO:0051246	237	0.034
protein ubiquitination	GO:0016567	118	0.034
purine nucleoside metabolic process	GO:0042278	380	0.034
carbohydrate biosynthetic process	GO:0016051	82	0.034
organonitrogen compound catabolic process	GO:1901565	404	0.034
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.033
carboxylic acid catabolic process	GO:0046395	71	0.033
purine containing compound metabolic process	GO:0072521	400	0.033
organonitrogen compound biosynthetic process	GO:1901566	314	0.032
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.032
cell growth	GO:0016049	89	0.031
carbohydrate derivative metabolic process	GO:1901135	549	0.031
translation	GO:0006412	230	0.031
protein localization to organelle	GO:0033365	337	0.031
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.030
organic hydroxy compound metabolic process	GO:1901615	125	0.030
energy derivation by oxidation of organic compounds	GO:0015980	125	0.030
response to heat	GO:0009408	69	0.030
atp metabolic process	GO:0046034	251	0.029
posttranscriptional regulation of gene expression	GO:0010608	115	0.029
response to nutrient levels	GO:0031667	150	0.029
protein catabolic process	GO:0030163	221	0.029
cellular carbohydrate metabolic process	GO:0044262	135	0.029
positive regulation of protein metabolic process	GO:0051247	93	0.029
homeostatic process	GO:0042592	227	0.029
regulation of catabolic process	GO:0009894	199	0.028
protein targeting to vacuole	GO:0006623	91	0.028
cell aging	GO:0007569	70	0.028
chemical homeostasis	GO:0048878	137	0.028
generation of precursor metabolites and energy	GO:0006091	147	0.028
filamentous growth	GO:0030447	124	0.028
positive regulation of macromolecule metabolic process	GO:0010604	394	0.028
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.028
organic acid catabolic process	GO:0016054	71	0.027
cellular response to dna damage stimulus	GO:0006974	287	0.027
glycosyl compound metabolic process	GO:1901657	398	0.027
cellular component assembly involved in morphogenesis	GO:0010927	73	0.027
regulation of catalytic activity	GO:0050790	307	0.027
cellular response to organic substance	GO:0071310	159	0.027
external encapsulating structure organization	GO:0045229	146	0.027
monosaccharide metabolic process	GO:0005996	83	0.027
mitotic nuclear division	GO:0007067	131	0.026
phosphorylation	GO:0016310	291	0.026
vesicle mediated transport	GO:0016192	335	0.026
proteolysis	GO:0006508	268	0.025
invasive growth in response to glucose limitation	GO:0001403	61	0.025
cellular response to chemical stimulus	GO:0070887	315	0.025
multi organism cellular process	GO:0044764	120	0.025
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.025
nucleoside triphosphate metabolic process	GO:0009141	364	0.025
regulation of cellular protein metabolic process	GO:0032268	232	0.025
nucleobase containing small molecule metabolic process	GO:0055086	491	0.024
filamentous growth of a population of unicellular organisms	GO:0044182	109	0.024
response to organic substance	GO:0010033	182	0.024
response to extracellular stimulus	GO:0009991	156	0.024
establishment of protein localization to vacuole	GO:0072666	91	0.024
ribonucleotide metabolic process	GO:0009259	377	0.024
alcohol metabolic process	GO:0006066	112	0.024
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.024
protein targeting	GO:0006605	272	0.024
protein modification by small protein conjugation	GO:0032446	144	0.023
ribonucleoside metabolic process	GO:0009119	389	0.023
regulation of gene expression epigenetic	GO:0040029	147	0.023
polysaccharide metabolic process	GO:0005976	60	0.023
growth	GO:0040007	157	0.023
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.022
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.022
nucleoside phosphate metabolic process	GO:0006753	458	0.022
response to inorganic substance	GO:0010035	47	0.022
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.021
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.021
ubiquitin dependent protein catabolic process	GO:0006511	181	0.021
cell wall organization or biogenesis	GO:0071554	190	0.021
nucleobase containing compound catabolic process	GO:0034655	479	0.021
response to starvation	GO:0042594	96	0.021
glucose metabolic process	GO:0006006	65	0.021
mitochondrion organization	GO:0007005	261	0.020
nuclear export	GO:0051168	124	0.020
mitotic cell cycle	GO:0000278	306	0.020
regulation of cellular catabolic process	GO:0031329	195	0.020
purine nucleoside monophosphate metabolic process	GO:0009126	262	0.020
regulation of protein modification process	GO:0031399	110	0.020
regulation of organelle organization	GO:0033043	243	0.019
positive regulation of gene expression	GO:0010628	321	0.019
ribonucleoprotein complex subunit organization	GO:0071826	152	0.019
monocarboxylic acid metabolic process	GO:0032787	122	0.019
protein complex assembly	GO:0006461	302	0.019
organelle assembly	GO:0070925	118	0.019
heterocycle catabolic process	GO:0046700	494	0.019
positive regulation of rna metabolic process	GO:0051254	294	0.018
ribonucleoprotein complex assembly	GO:0022618	143	0.018
negative regulation of gene expression epigenetic	GO:0045814	147	0.018
purine ribonucleotide metabolic process	GO:0009150	372	0.018
hexose biosynthetic process	GO:0019319	30	0.018
regulation of cellular component organization	GO:0051128	334	0.018
transmembrane transport	GO:0055085	349	0.018
positive regulation of cellular protein metabolic process	GO:0032270	89	0.018
cellular response to nutrient levels	GO:0031669	144	0.018
establishment of protein localization	GO:0045184	367	0.018
signaling	GO:0023052	208	0.018
alcohol biosynthetic process	GO:0046165	75	0.017
intracellular protein transport	GO:0006886	319	0.017
purine nucleoside catabolic process	GO:0006152	330	0.017
gluconeogenesis	GO:0006094	30	0.017
phospholipid metabolic process	GO:0006644	125	0.017
negative regulation of rna metabolic process	GO:0051253	262	0.017
mitotic cell cycle process	GO:1903047	294	0.017
modification dependent protein catabolic process	GO:0019941	181	0.017
aging	GO:0007568	71	0.017
carbohydrate derivative biosynthetic process	GO:1901137	181	0.017
rrna containing ribonucleoprotein complex export from nucleus	GO:0071428	46	0.017
ribose phosphate metabolic process	GO:0019693	384	0.017
glycosyl compound catabolic process	GO:1901658	335	0.017
protein transport	GO:0015031	345	0.017
spindle pole body organization	GO:0051300	33	0.016
aromatic compound catabolic process	GO:0019439	491	0.016
organic hydroxy compound biosynthetic process	GO:1901617	81	0.016
response to abiotic stimulus	GO:0009628	159	0.016
protein localization to vacuole	GO:0072665	92	0.016
cytoskeleton organization	GO:0007010	230	0.016
purine containing compound catabolic process	GO:0072523	332	0.016
regulation of phosphorus metabolic process	GO:0051174	230	0.016
regulation of cellular component biogenesis	GO:0044087	112	0.016
negative regulation of cellular component organization	GO:0051129	109	0.016
response to osmotic stress	GO:0006970	83	0.016
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	137	0.015
nuclear transport	GO:0051169	165	0.015
cellular lipid catabolic process	GO:0044242	33	0.015
cellular response to external stimulus	GO:0071496	150	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.015
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.015
regulation of transcription from rna polymerase ii promoter in response to zinc ion starvation	GO:0034225	3	0.015
sulfite transport	GO:0000316	2	0.015
gene silencing	GO:0016458	151	0.015
positive regulation of biosynthetic process	GO:0009891	336	0.015
alpha amino acid metabolic process	GO:1901605	124	0.015
nucleoside monophosphate metabolic process	GO:0009123	267	0.015
positive regulation of cellular biosynthetic process	GO:0031328	336	0.015
cell cycle g1 s phase transition	GO:0044843	64	0.015
dna recombination	GO:0006310	172	0.015
ion transport	GO:0006811	274	0.015
nucleic acid phosphodiester bond hydrolysis	GO:0090305	194	0.015
regulation of cell communication	GO:0010646	124	0.015
cell cycle phase transition	GO:0044770	144	0.014
response to uv	GO:0009411	4	0.014
fungal type cell wall organization	GO:0031505	145	0.014
ncrna processing	GO:0034470	330	0.014
organic cyclic compound catabolic process	GO:1901361	499	0.014
chromatin remodeling	GO:0006338	80	0.014
microtubule organizing center organization	GO:0031023	33	0.014
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.014
regulation of transport	GO:0051049	85	0.014
cellular nitrogen compound catabolic process	GO:0044270	494	0.014
regulation of response to stress	GO:0080134	57	0.014
protein complex biogenesis	GO:0070271	314	0.014
cellular component disassembly	GO:0022411	86	0.014
invasive filamentous growth	GO:0036267	65	0.014
establishment of protein localization to organelle	GO:0072594	278	0.014
protein import	GO:0017038	122	0.014
meiotic nuclear division	GO:0007126	163	0.014
regulation of localization	GO:0032879	127	0.013
regulation of signaling	GO:0023051	119	0.013
cation transport	GO:0006812	166	0.013
dna repair	GO:0006281	236	0.013
vacuolar transport	GO:0007034	145	0.013
regulation of growth of unicellular organism as a thread of attached cells	GO:0070784	31	0.013
translational elongation	GO:0006414	32	0.013
cellular response to pheromone	GO:0071444	88	0.013
establishment of protein localization to membrane	GO:0090150	99	0.013
cellular amino acid metabolic process	GO:0006520	225	0.013
cell morphogenesis	GO:0000902	30	0.013
modification dependent macromolecule catabolic process	GO:0043632	203	0.013
regulation of phosphate metabolic process	GO:0019220	230	0.013
cellular response to starvation	GO:0009267	90	0.013
regulation of cell cycle process	GO:0010564	150	0.013
regulation of molecular function	GO:0065009	320	0.013
protein localization to membrane	GO:0072657	102	0.013
nucleoside catabolic process	GO:0009164	335	0.013
cellular ketone metabolic process	GO:0042180	63	0.012
monocarboxylic acid catabolic process	GO:0072329	26	0.012
response to organic cyclic compound	GO:0014070	1	0.012
regulation of protein ubiquitination	GO:0031396	20	0.012
regulation of translation	GO:0006417	89	0.012
histone modification	GO:0016570	119	0.012
nucleocytoplasmic transport	GO:0006913	163	0.012
steroid metabolic process	GO:0008202	47	0.012
coenzyme metabolic process	GO:0006732	104	0.012
cellular amino acid biosynthetic process	GO:0008652	118	0.012
regulation of transcription by chromatin organization	GO:0034401	19	0.012
telomere organization	GO:0032200	75	0.011
cellular response to freezing	GO:0071497	4	0.011
negative regulation of protein metabolic process	GO:0051248	85	0.011
purine nucleotide metabolic process	GO:0006163	376	0.011
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.011
cellular response to anoxia	GO:0071454	3	0.011
guanosine containing compound catabolic process	GO:1901069	109	0.011
negative regulation of ergosterol biosynthetic process	GO:0010895	1	0.011
regulation of cell division	GO:0051302	113	0.011
oxidative phosphorylation	GO:0006119	26	0.011
cellular metal ion homeostasis	GO:0006875	78	0.011
regulation of response to stimulus	GO:0048583	157	0.011
positive regulation of cell cycle	GO:0045787	32	0.011
response to hydrostatic pressure	GO:0051599	2	0.011
positive regulation of cytokinesis	GO:0032467	2	0.011
regulation of lipid catabolic process	GO:0050994	4	0.011
ribonucleotide catabolic process	GO:0009261	327	0.011
cellular response to blue light	GO:0071483	2	0.011
cell division	GO:0051301	205	0.011
positive regulation of catabolic process	GO:0009896	135	0.010
purine ribonucleoside catabolic process	GO:0046130	330	0.010
spore wall biogenesis	GO:0070590	52	0.010
regulation of carbohydrate metabolic process	GO:0006109	43	0.010
signal transduction	GO:0007165	208	0.010
protein modification by small protein conjugation or removal	GO:0070647	172	0.010
macromolecular complex disassembly	GO:0032984	80	0.010
positive regulation of response to stimulus	GO:0048584	37	0.010
regulation of protein modification by small protein conjugation or removal	GO:1903320	29	0.010
negative regulation of cellular hyperosmotic salinity response by negative regulation of transcription from rna polymerase ii promoter	GO:1900464	2	0.010
cell wall macromolecule metabolic process	GO:0044036	27	0.010
mitotic cell cycle phase transition	GO:0044772	141	0.010
nucleoside triphosphate catabolic process	GO:0009143	329	0.010

SHC1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.025

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