Saccharomyces cerevisiae

20 known processes

MDH1 (YKL085W)

Mdh1p

MDH1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
energy derivation by oxidation of organic compoundsGO:00159801250.964
coenzyme metabolic processGO:00067321040.768
oxidation reduction processGO:00551143530.673
cofactor metabolic processGO:00511861260.650
nucleotide metabolic processGO:00091174530.615
generation of precursor metabolites and energyGO:00060911470.600
organophosphate metabolic processGO:00196375970.556
cellular protein complex assemblyGO:00436232090.444
mitochondrial electron transport ubiquinol to cytochrome cGO:0006122110.431
aerobic respirationGO:0009060550.421
nucleoside phosphate metabolic processGO:00067534580.357
nicotinamide nucleotide metabolic processGO:0046496440.315
oxidoreduction coenzyme metabolic processGO:0006733580.272
cellular respirationGO:0045333820.271
atp synthesis coupled electron transportGO:0042773250.256
tricarboxylic acid metabolic processGO:007235030.233
cytochrome complex assemblyGO:0017004290.229
nadh metabolic processGO:0006734120.204
nucleobase containing small molecule metabolic processGO:00550864910.191
monocarboxylic acid metabolic processGO:00327871220.185
pyridine nucleotide metabolic processGO:0019362450.183
purine ribonucleoside triphosphate biosynthetic processGO:0009206170.181
protein complex assemblyGO:00064613020.178
mitochondrial atp synthesis coupled electron transportGO:0042775250.177
translationGO:00064122300.159
nucleoside triphosphate metabolic processGO:00091413640.150
ribonucleoside metabolic processGO:00091193890.147
dicarboxylic acid metabolic processGO:0043648200.145
glycosyl compound metabolic processGO:19016573980.144
oxoacid metabolic processGO:00434363510.143
nucleoside monophosphate metabolic processGO:00091232670.142
purine ribonucleoside triphosphate metabolic processGO:00092053540.136
tricarboxylic acid cycleGO:000609960.133
purine ribonucleotide metabolic processGO:00091503720.129
carbohydrate derivative metabolic processGO:19011355490.128
organic acid metabolic processGO:00060823520.124
acyl coa metabolic processGO:0006637130.115
ribonucleotide metabolic processGO:00092593770.114
detection of glucoseGO:005159430.111
response to organic cyclic compoundGO:001407010.111
regulation of cellular component organizationGO:00511283340.106
cellular nitrogen compound catabolic processGO:00442704940.105
electron transport chainGO:0022900250.105
transmembrane transportGO:00550853490.100
developmental processGO:00325022610.099
cell agingGO:0007569700.089
purine ribonucleoside metabolic processGO:00461283800.082
protein complex biogenesisGO:00702713140.079
regulation of phosphate metabolic processGO:00192202300.075
cellular amine metabolic processGO:0044106510.075
mitochondrial translationGO:0032543520.074
hydrogen ion transmembrane transportGO:1902600490.073
ribose phosphate metabolic processGO:00196933840.072
nucleotide biosynthetic processGO:0009165790.072
purine ribonucleoside monophosphate metabolic processGO:00091672620.069
single organism catabolic processGO:00447126190.067
regulation of meiotic cell cycleGO:0051445430.066
aromatic compound catabolic processGO:00194394910.066
nucleoside triphosphate catabolic processGO:00091433290.066
respiratory electron transport chainGO:0022904250.066
thioester metabolic processGO:0035383130.065
negative regulation of protein metabolic processGO:0051248850.065
cellular response to chemical stimulusGO:00708873150.064
regulation of cellular amine metabolic processGO:0033238210.064
single organism membrane organizationGO:00448022750.063
heterocycle catabolic processGO:00467004940.062
amine metabolic processGO:0009308510.062
purine nucleoside triphosphate metabolic processGO:00091443560.061
protein transmembrane transportGO:0071806820.061
purine nucleoside monophosphate metabolic processGO:00091262620.060
negative regulation of cellular protein metabolic processGO:0032269850.059
pyridine containing compound metabolic processGO:0072524530.058
response to chemicalGO:00422213900.058
organophosphate biosynthetic processGO:00904071820.057
regulation of phosphorus metabolic processGO:00511742300.057
regulation of translationGO:0006417890.055
branched chain amino acid metabolic processGO:0009081160.054
nad metabolic processGO:0019674250.054
response to organic substanceGO:00100331820.053
ribonucleotide catabolic processGO:00092613270.053
gtp metabolic processGO:00460391070.053
purine nucleotide metabolic processGO:00061633760.052
mitochondrial genome maintenanceGO:0000002400.052
protein transportGO:00150313450.051
detection of hexose stimulusGO:000973230.049
negative regulation of organelle organizationGO:00106391030.049
single organism developmental processGO:00447672580.048
carbohydrate metabolic processGO:00059752520.047
protein dna complex subunit organizationGO:00718241530.047
purine nucleotide catabolic processGO:00061953280.045
nucleotide catabolic processGO:00091663300.045
ribonucleoside triphosphate catabolic processGO:00092033270.045
regulation of cellular protein metabolic processGO:00322682320.044
ribonucleoside triphosphate metabolic processGO:00091993560.043
glucose metabolic processGO:0006006650.043
nucleobase containing compound catabolic processGO:00346554790.042
energy coupled proton transport down electrochemical gradientGO:0015985170.042
phosphorylationGO:00163102910.042
cofactor biosynthetic processGO:0051188800.042
purine ribonucleoside catabolic processGO:00461303300.042
positive regulation of apoptotic processGO:004306530.041
small molecule biosynthetic processGO:00442832580.040
establishment of protein localizationGO:00451843670.040
developmental process involved in reproductionGO:00030061590.039
mitochondrion organizationGO:00070052610.039
organonitrogen compound biosynthetic processGO:19015663140.039
nucleoside catabolic processGO:00091643350.037
purine nucleoside metabolic processGO:00422783800.037
purine ribonucleotide catabolic processGO:00091543270.037
organonitrogen compound catabolic processGO:19015654040.037
reproductive processGO:00224142480.037
carboxylic acid metabolic processGO:00197523380.037
cellular amino acid biosynthetic processGO:00086521180.036
purine containing compound catabolic processGO:00725233320.036
chromatin silencing at rdnaGO:0000183320.036
ribonucleoside monophosphate metabolic processGO:00091612650.035
detection of monosaccharide stimulusGO:003428730.035
negative regulation of macromolecule metabolic processGO:00106053750.035
cellular developmental processGO:00488691910.034
atp metabolic processGO:00460342510.034
cytoplasmic translationGO:0002181650.034
inorganic ion transmembrane transportGO:00986601090.034
nucleoside metabolic processGO:00091163940.033
purine containing compound metabolic processGO:00725214000.033
macromolecular complex disassemblyGO:0032984800.033
nucleoside phosphate biosynthetic processGO:1901293800.033
regulation of molecular functionGO:00650093200.032
purine nucleoside catabolic processGO:00061523300.032
organic cyclic compound catabolic processGO:19013614990.032
agingGO:0007568710.031
negative regulation of cellular component organizationGO:00511291090.031
negative regulation of cell cycleGO:0045786910.031
positive regulation of macromolecule biosynthetic processGO:00105573250.031
purine nucleotide biosynthetic processGO:0006164410.030
purine ribonucleoside monophosphate biosynthetic processGO:0009168280.029
carbohydrate derivative catabolic processGO:19011363390.028
organophosphate catabolic processGO:00464343380.027
regulation of catalytic activityGO:00507903070.027
sulfur compound metabolic processGO:0006790950.027
negative regulation of cell cycle processGO:0010948860.027
negative regulation of protein modification processGO:0031400370.026
ribonucleoside catabolic processGO:00424543320.026
cellular response to organic substanceGO:00713101590.026
regulation of generation of precursor metabolites and energyGO:0043467230.025
regulation of protein metabolic processGO:00512462370.025
cell differentiationGO:00301541610.025
nuclear exportGO:00511681240.025
mitochondrial respiratory chain complex assemblyGO:0033108360.025
carbon catabolite activation of transcriptionGO:0045991260.024
cellular ketone metabolic processGO:0042180630.023
glycosyl compound catabolic processGO:19016583350.023
regulation of signalingGO:00230511190.023
regulation of dna replicationGO:0006275510.023
purine containing compound biosynthetic processGO:0072522530.022
regulation of cell cycle processGO:00105641500.022
response to extracellular stimulusGO:00099911560.022
carboxylic acid biosynthetic processGO:00463941520.021
positive regulation of cellular component organizationGO:00511301160.021
response to external stimulusGO:00096051580.021
alcohol biosynthetic processGO:0046165750.021
positive regulation of phosphorus metabolic processGO:00105621470.020
positive regulation of rna metabolic processGO:00512542940.020
single organism cellular localizationGO:19025803750.020
regulation of catabolic processGO:00098941990.020
nucleoside triphosphate biosynthetic processGO:0009142220.020
carbon catabolite regulation of transcriptionGO:0045990390.020
tetrapyrrole biosynthetic processGO:0033014140.020
mitochondrial respiratory chain complex iv biogenesisGO:0097034260.020
phospholipid metabolic processGO:00066441250.020
cellular amino acid metabolic processGO:00065202250.019
intracellular protein transmembrane importGO:0044743670.019
organelle localizationGO:00516401280.019
purine ribonucleotide biosynthetic processGO:0009152390.018
inorganic cation transmembrane transportGO:0098662980.018
covalent chromatin modificationGO:00165691190.018
purine ribonucleoside triphosphate catabolic processGO:00092073270.018
regulation of protein modification processGO:00313991100.017
regulation of transferase activityGO:0051338830.017
protein maturationGO:0051604760.017
mitochondrial respiratory chain complex iv assemblyGO:0033617180.017
negative regulation of biosynthetic processGO:00098903120.017
posttranscriptional regulation of gene expressionGO:00106081150.017
glycerolipid metabolic processGO:00464861080.017
tetrapyrrole metabolic processGO:0033013150.017
regulation of meiosisGO:0040020420.017
positive regulation of organelle organizationGO:0010638850.016
regulation of phosphorylationGO:0042325860.016
regulation of nuclear divisionGO:00517831030.016
cell morphogenesisGO:0000902300.016
purine nucleoside monophosphate biosynthetic processGO:0009127280.016
regulation of cellular catabolic processGO:00313291950.016
establishment of protein localization to mitochondrionGO:0072655630.016
chromatin organizationGO:00063252420.016
coenzyme biosynthetic processGO:0009108660.016
positive regulation of protein metabolic processGO:0051247930.015
organic hydroxy compound metabolic processGO:19016151250.015
positive regulation of nucleotide metabolic processGO:00459811010.015
regulation of organelle organizationGO:00330432430.015
negative regulation of phosphorus metabolic processGO:0010563490.015
protein phosphorylationGO:00064681970.015
nucleoside phosphate catabolic processGO:19012923310.015
regulation of nucleotide metabolic processGO:00061401100.015
regulation of cellular amino acid metabolic processGO:0006521160.015
positive regulation of cellular amine metabolic processGO:0033240100.014
mitotic cell cycle processGO:19030472940.014
ribonucleoprotein complex subunit organizationGO:00718261520.014
mitochondrial respiratory chain complex iii biogenesisGO:0097033110.014
positive regulation of cell deathGO:001094230.014
monosaccharide metabolic processGO:0005996830.014
guanosine containing compound catabolic processGO:19010691090.014
protein localization to plasma membraneGO:0072659180.014
carbohydrate biosynthetic processGO:0016051820.014
regulation of protein phosphorylationGO:0001932750.014
nucleoside monophosphate biosynthetic processGO:0009124330.014
regulation of cell cycleGO:00517261950.014
cellular response to nutrient levelsGO:00316691440.014
cellular cation homeostasisGO:00300031000.014
regulation of purine nucleotide metabolic processGO:19005421090.014
regulation of nucleoside metabolic processGO:00091181060.014
single organism reproductive processGO:00447021590.014
anatomical structure homeostasisGO:0060249740.013
cell cycle checkpointGO:0000075820.013
regulation of phosphatidylcholine biosynthetic processGO:200124570.013
carbon catabolite regulation of transcription from rna polymerase ii promoterGO:0000429340.013
ribonucleotide biosynthetic processGO:0009260440.013
intracellular protein transportGO:00068863190.013
rna transportGO:0050658920.013
positive regulation of biosynthetic processGO:00098913360.013
detection of chemical stimulusGO:000959330.013
cellular biogenic amine metabolic processGO:0006576370.013
ribose phosphate biosynthetic processGO:0046390500.013
positive regulation of molecular functionGO:00440931850.013
signal transductionGO:00071652080.013
regulation of cellular carbohydrate metabolic processGO:0010675410.013
single organism carbohydrate metabolic processGO:00447232370.013
protein localization to membraneGO:00726571020.013
respiratory chain complex iv assemblyGO:0008535180.013
meiotic nuclear divisionGO:00071261630.013
negative regulation of cellular metabolic processGO:00313244070.013
positive regulation of programmed cell deathGO:004306830.013
positive regulation of intracellular protein transportGO:009031630.012
atp catabolic processGO:00062002240.012
establishment of rna localizationGO:0051236920.012
positive regulation of secretionGO:005104720.012
nucleoside biosynthetic processGO:0009163380.012
hexose metabolic processGO:0019318780.012
negative regulation of transferase activityGO:0051348310.012
divalent inorganic cation homeostasisGO:0072507210.012
monovalent inorganic cation transportGO:0015672780.012
pigment biosynthetic processGO:0046148220.012
positive regulation of cellular biosynthetic processGO:00313283360.012
positive regulation of purine nucleotide metabolic processGO:19005441000.012
positive regulation of gene expressionGO:00106283210.012
purine nucleoside triphosphate biosynthetic processGO:0009145170.012
intracellular protein transmembrane transportGO:0065002800.012
autophagyGO:00069141060.012
protein localization to mitochondrionGO:0070585630.012
leucine metabolic processGO:000655180.012
regulation of nucleotide catabolic processGO:00308111060.012
response to oxidative stressGO:0006979990.012
regulation of hydrolase activityGO:00513361330.011
multi organism processGO:00517042330.011
histone modificationGO:00165701190.011
rna localizationGO:00064031120.011
protein foldingGO:0006457940.011
regulation of mitochondrion organizationGO:0010821200.011
regulation of cell cycle phase transitionGO:1901987700.011
response to starvationGO:0042594960.011
cellular homeostasisGO:00197251380.011
regulation of cell divisionGO:00513021130.011
replicative cell agingGO:0001302460.011
homeostatic processGO:00425922270.011
positive regulation of cellular protein metabolic processGO:0032270890.011
alpha amino acid metabolic processGO:19016051240.011
regulation of mitochondrial translationGO:0070129150.011
phospholipid biosynthetic processGO:0008654890.010
negative regulation of nuclear divisionGO:0051784620.010
regulation of cellular respirationGO:004345770.010
cell communicationGO:00071543450.010
ribonucleoside monophosphate biosynthetic processGO:0009156310.010
response to endogenous stimulusGO:0009719260.010
anatomical structure developmentGO:00488561600.010
positive regulation of cellular catabolic processGO:00313311280.010
organic acid biosynthetic processGO:00160531520.010

MDH1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.026
cancerDOID:16200.026
disease of cellular proliferationDOID:1456600.026
disease of anatomical entityDOID:700.014
inherited metabolic disorderDOID:65500.010
disease of metabolismDOID:001466700.010