IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

50 known processes

KIP1 (YBL063W)

Kip1p

(Aliases: CIN9)

SGD: S000000159
Entrez: 852216
UniProtKB: P28742

Process Predictions
Disease Predictions

KIP1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
microtubule based process	GO:0007017	117	0.747
mitotic sister chromatid segregation	GO:0000070	85	0.736
microtubule cytoskeleton organization	GO:0000226	109	0.723
sister chromatid segregation	GO:0000819	93	0.588
cytoskeleton organization	GO:0007010	230	0.557
mitotic cell cycle process	GO:1903047	294	0.488
metaphase anaphase transition of cell cycle	GO:0044784	28	0.469
regulation of metaphase anaphase transition of cell cycle	GO:1902099	27	0.448
regulation of mitotic sister chromatid separation	GO:0010965	29	0.447
mitotic spindle assembly checkpoint	GO:0007094	23	0.383
mitotic sister chromatid separation	GO:0051306	26	0.373
regulation of mitotic metaphase anaphase transition	GO:0030071	27	0.357
negative regulation of metaphase anaphase transition of cell cycle	GO:1902100	23	0.349
regulation of mitotic sister chromatid segregation	GO:0033047	30	0.314
negative regulation of mitotic metaphase anaphase transition	GO:0045841	23	0.313
negative regulation of mitotic sister chromatid separation	GO:2000816	23	0.307
chromosome segregation	GO:0007059	159	0.300
metaphase anaphase transition of mitotic cell cycle	GO:0007091	28	0.294
mitotic spindle organization	GO:0007052	30	0.285
negative regulation of chromosome segregation	GO:0051985	25	0.274
regulation of organelle organization	GO:0033043	243	0.256	Fly
negative regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032435	24	0.244
attachment of spindle microtubules to kinetochore	GO:0008608	25	0.239
spindle organization	GO:0007051	37	0.239
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process	GO:0031145	35	0.231
negative regulation of mitotic sister chromatid segregation	GO:0033048	24	0.219
single organism catabolic process	GO:0044712	619	0.213
mitotic spindle checkpoint	GO:0071174	34	0.208
meiotic cell cycle process	GO:1903046	229	0.190
negative regulation of cell division	GO:0051782	66	0.189
negative regulation of proteolysis	GO:0045861	33	0.187
chromosome separation	GO:0051304	33	0.187
mitotic cell cycle	GO:0000278	306	0.182
negative regulation of proteasomal protein catabolic process	GO:1901799	25	0.181
negative regulation of sister chromatid segregation	GO:0033046	24	0.171
cell cycle phase transition	GO:0044770	144	0.170
microtubule polymerization or depolymerization	GO:0031109	36	0.168
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	30	0.165
spindle checkpoint	GO:0031577	35	0.164
negative regulation of proteolysis involved in cellular protein catabolic process	GO:1903051	27	0.163
negative regulation of cellular protein catabolic process	GO:1903363	27	0.162
macromolecular complex disassembly	GO:0032984	80	0.155
cellular component disassembly	GO:0022411	86	0.152
negative regulation of protein catabolic process	GO:0042177	27	0.149
modification dependent macromolecule catabolic process	GO:0043632	203	0.147
negative regulation of protein maturation	GO:1903318	33	0.147
regulation of sister chromatid segregation	GO:0033045	30	0.136
microtubule anchoring	GO:0034453	25	0.131
negative regulation of chromosome organization	GO:2001251	39	0.130
negative regulation of mitosis	GO:0045839	39	0.129
mitotic cell cycle phase transition	GO:0044772	141	0.129
spindle assembly checkpoint	GO:0071173	23	0.128
chromosome localization	GO:0050000	20	0.127
modification dependent protein catabolic process	GO:0019941	181	0.126
maintenance of location	GO:0051235	66	0.123
negative regulation of organelle organization	GO:0010639	103	0.122	Fly
regulation of chromosome segregation	GO:0051983	44	0.121
negative regulation of cellular catabolic process	GO:0031330	43	0.120
regulation of nuclear division	GO:0051783	103	0.118
regulation of protein maturation	GO:1903317	34	0.118
establishment of protein localization	GO:0045184	367	0.118	Fly
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	137	0.117
regulation of cellular protein metabolic process	GO:0032268	232	0.117
cellular protein complex assembly	GO:0043623	209	0.116
regulation of proteasomal protein catabolic process	GO:0061136	34	0.113
mitotic metaphase plate congression	GO:0007080	8	0.109
meiotic chromosome segregation	GO:0045132	31	0.107
negative regulation of cellular metabolic process	GO:0031324	407	0.107
sister chromatid biorientation	GO:0031134	8	0.106
maintenance of protein location	GO:0045185	53	0.105
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	36	0.105
meiotic cell cycle	GO:0051321	272	0.105
negative regulation of protein processing	GO:0010955	33	0.104
ubiquitin dependent protein catabolic process	GO:0006511	181	0.103
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.101
cellular protein catabolic process	GO:0044257	213	0.100
organelle assembly	GO:0070925	118	0.100
sister chromatid cohesion	GO:0007062	49	0.099
regulation of protein catabolic process	GO:0042176	40	0.099
protein catabolic process	GO:0030163	221	0.098
regulation of cytoskeleton organization	GO:0051493	63	0.097	Fly
regulation of cellular protein catabolic process	GO:1903362	36	0.097
regulation of protein metabolic process	GO:0051246	237	0.096
regulation of protein processing	GO:0070613	34	0.095
negative regulation of nuclear division	GO:0051784	62	0.095
regulation of mitosis	GO:0007088	65	0.093
mitotic sister chromatid cohesion	GO:0007064	38	0.092
negative regulation of catabolic process	GO:0009895	43	0.090
proteasomal protein catabolic process	GO:0010498	141	0.089
cellular macromolecule catabolic process	GO:0044265	363	0.087
regulation of biological quality	GO:0065008	391	0.087
maintenance of protein location in cell	GO:0032507	50	0.087
protein dna complex subunit organization	GO:0071824	153	0.085
proteolysis	GO:0006508	268	0.085
microtubule cytoskeleton organization involved in mitosis	GO:1902850	13	0.084
establishment of protein localization to organelle	GO:0072594	278	0.084
protein localization to organelle	GO:0033365	337	0.083
protein processing	GO:0016485	64	0.083
mitotic nuclear division	GO:0007067	131	0.082
single organism cellular localization	GO:1902580	375	0.079
regulation of proteolysis	GO:0030162	44	0.078
negative regulation of macromolecule metabolic process	GO:0010605	375	0.076
regulation of cell division	GO:0051302	113	0.076
organelle localization	GO:0051640	128	0.074
negative regulation of cell cycle phase transition	GO:1901988	59	0.074
protein complex assembly	GO:0006461	302	0.072
cell division	GO:0051301	205	0.069
organelle fission	GO:0048285	272	0.068
negative regulation of cell cycle process	GO:0010948	86	0.066
protein complex disassembly	GO:0043241	70	0.066
negative regulation of cellular component organization	GO:0051129	109	0.066	Fly
protein maturation	GO:0051604	76	0.066
establishment of organelle localization	GO:0051656	96	0.064
negative regulation of protein metabolic process	GO:0051248	85	0.064
negative regulation of cellular protein metabolic process	GO:0032269	85	0.064
cellular protein complex disassembly	GO:0043624	42	0.062
mitotic cell cycle checkpoint	GO:0007093	56	0.062
macromolecule catabolic process	GO:0009057	383	0.062
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.062
regulation of cell cycle process	GO:0010564	150	0.062	Fly
spindle assembly	GO:0051225	9	0.060
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.060
regulation of microtubule based process	GO:0032886	32	0.059	Fly
regulation of cellular component organization	GO:0051128	334	0.057	Fly
filamentous growth	GO:0030447	124	0.057
regulation of microtubule cytoskeleton organization	GO:0070507	32	0.056	Fly
meiotic nuclear division	GO:0007126	163	0.055
regulation of cellular catabolic process	GO:0031329	195	0.054
regulation of chromosome organization	GO:0033044	66	0.051
regulation of catabolic process	GO:0009894	199	0.051
cell cycle checkpoint	GO:0000075	82	0.050
nuclear division	GO:0000280	263	0.050
mitotic spindle elongation	GO:0000022	14	0.048
regulation of cell cycle phase transition	GO:1901987	70	0.046
regulation of mitotic cell cycle	GO:0007346	107	0.045	Fly
regulation of cell cycle	GO:0051726	195	0.045	Fly
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.044
protein depolymerization	GO:0051261	21	0.044
negative regulation of gene expression	GO:0010629	312	0.044
attachment of mitotic spindle microtubules to kinetochore	GO:0051315	9	0.041
chromosome condensation	GO:0030261	19	0.041
negative regulation of cell cycle	GO:0045786	91	0.039
regulation of microtubule polymerization or depolymerization	GO:0031110	18	0.038	Fly
protein complex biogenesis	GO:0070271	314	0.037
negative regulation of cytoskeleton organization	GO:0051494	24	0.036	Fly
filamentous growth of a population of unicellular organisms	GO:0044182	109	0.036
protein dna complex assembly	GO:0065004	105	0.033
chromosome organization involved in meiosis	GO:0070192	32	0.031
protein transport	GO:0015031	345	0.031	Fly
negative regulation of molecular function	GO:0044092	68	0.030
negative regulation of mitotic cell cycle	GO:0045930	63	0.029
microtubule polymerization	GO:0046785	30	0.029
telomere organization	GO:0032200	75	0.028
cellular response to chemical stimulus	GO:0070887	315	0.028
regulation of catalytic activity	GO:0050790	307	0.028
endocytosis	GO:0006897	90	0.027
response to organic cyclic compound	GO:0014070	1	0.027
reproduction of a single celled organism	GO:0032505	191	0.027
microtubule depolymerization	GO:0007019	8	0.027
reproductive process	GO:0022414	248	0.026
metaphase plate congression	GO:0051310	8	0.026
response to chemical	GO:0042221	390	0.026
regulation of molecular function	GO:0065009	320	0.026
spindle pole body organization	GO:0051300	33	0.025
negative regulation of protein depolymerization	GO:1901880	12	0.025	Fly
glycosyl compound metabolic process	GO:1901657	398	0.025
regulation of protein complex assembly	GO:0043254	77	0.025
regulation of cellular component biogenesis	GO:0044087	112	0.025
protein localization to chromosome	GO:0034502	28	0.025
dna packaging	GO:0006323	55	0.024
negative regulation of protein complex disassembly	GO:0043242	14	0.024	Fly
spindle stabilization	GO:0043146	2	0.024	Fly
pseudohyphal growth	GO:0007124	75	0.023
maintenance of location in cell	GO:0051651	58	0.023
protein targeting	GO:0006605	272	0.023
ribose phosphate metabolic process	GO:0019693	384	0.023
cell communication	GO:0007154	345	0.023
spindle pole body separation	GO:0000073	13	0.023
purine ribonucleoside metabolic process	GO:0046128	380	0.022
nucleic acid phosphodiester bond hydrolysis	GO:0090305	194	0.022
organonitrogen compound catabolic process	GO:1901565	404	0.022
organophosphate metabolic process	GO:0019637	597	0.022
regulation of mitotic spindle organization	GO:0060236	8	0.022	Fly
microtubule nucleation	GO:0007020	17	0.022
positive regulation of organelle organization	GO:0010638	85	0.022
protein polymerization	GO:0051258	51	0.022
establishment or maintenance of cell polarity	GO:0007163	96	0.022
nucleoside metabolic process	GO:0009116	394	0.022
purine containing compound metabolic process	GO:0072521	400	0.021
regulation of protein polymerization	GO:0032271	33	0.021
positive regulation of macromolecule metabolic process	GO:0010604	394	0.021
purine nucleoside metabolic process	GO:0042278	380	0.021
reproductive process in single celled organism	GO:0022413	145	0.020
cytokinesis	GO:0000910	92	0.020
ribonucleoside metabolic process	GO:0009119	389	0.020
anatomical structure homeostasis	GO:0060249	74	0.020
purine ribonucleotide metabolic process	GO:0009150	372	0.020
spindle assembly involved in mitosis	GO:0090307	4	0.020
establishment of spindle orientation	GO:0051294	10	0.020
purine nucleotide metabolic process	GO:0006163	376	0.020
dna conformation change	GO:0071103	98	0.019
regulation of dna metabolic process	GO:0051052	100	0.019
establishment of mitotic sister chromatid cohesion	GO:0034087	15	0.018
nucleobase containing small molecule metabolic process	GO:0055086	491	0.018
cytokinetic process	GO:0032506	78	0.018
carbohydrate derivative metabolic process	GO:1901135	549	0.018
response to organic substance	GO:0010033	182	0.018
oxidation reduction process	GO:0055114	353	0.018
ribonucleotide metabolic process	GO:0009259	377	0.017
cell wall organization or biogenesis	GO:0071554	190	0.017
single organism developmental process	GO:0044767	258	0.017	Fly
meiotic sister chromatid segregation	GO:0045144	14	0.017
nucleoside phosphate metabolic process	GO:0006753	458	0.017
multi organism process	GO:0051704	233	0.016
glycosyl compound catabolic process	GO:1901658	335	0.016
positive regulation of cellular component organization	GO:0051130	116	0.016
organic cyclic compound catabolic process	GO:1901361	499	0.016
mitochondrion organization	GO:0007005	261	0.016
ribosome biogenesis	GO:0042254	335	0.016
negative regulation of protein polymerization	GO:0032272	12	0.016
mitochondrial genome maintenance	GO:0000002	40	0.016
nucleotide metabolic process	GO:0009117	453	0.015
cellular response to organic substance	GO:0071310	159	0.015
vesicle mediated transport	GO:0016192	335	0.015
conjugation with cellular fusion	GO:0000747	106	0.015
growth	GO:0040007	157	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.015
cellular nitrogen compound catabolic process	GO:0044270	494	0.015
positive regulation of cellular biosynthetic process	GO:0031328	336	0.015
negative regulation of catalytic activity	GO:0043086	60	0.015
positive regulation of biosynthetic process	GO:0009891	336	0.015
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.015
dephosphorylation	GO:0016311	127	0.015
nucleobase containing compound catabolic process	GO:0034655	479	0.015
regulation of spindle organization	GO:0090224	8	0.015	Fly
spindle elongation	GO:0051231	14	0.015
regulation of protein modification process	GO:0031399	110	0.015
regulation of hydrolase activity	GO:0051336	133	0.015
dna replication	GO:0006260	147	0.014
heterocycle catabolic process	GO:0046700	494	0.014
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.014
ribonucleotide catabolic process	GO:0009261	327	0.014
rdna condensation	GO:0070550	9	0.014
carbohydrate derivative catabolic process	GO:1901136	339	0.014
nucleoside monophosphate metabolic process	GO:0009123	267	0.014
purine containing compound catabolic process	GO:0072523	332	0.014
sexual reproduction	GO:0019953	216	0.014
dna dependent dna replication	GO:0006261	115	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.014
establishment of cell polarity	GO:0030010	64	0.014
nucleoside triphosphate metabolic process	GO:0009141	364	0.014
purine ribonucleoside catabolic process	GO:0046130	330	0.014
purine nucleoside catabolic process	GO:0006152	330	0.014
spindle localization	GO:0051653	14	0.014
nucleoside triphosphate catabolic process	GO:0009143	329	0.014
nucleoside catabolic process	GO:0009164	335	0.014
establishment of nucleus localization	GO:0040023	22	0.013
generation of precursor metabolites and energy	GO:0006091	147	0.013
aromatic compound catabolic process	GO:0019439	491	0.013
conjugation	GO:0000746	107	0.013
dna recombination	GO:0006310	172	0.013
organophosphate catabolic process	GO:0046434	338	0.013
nucleoside phosphate catabolic process	GO:1901292	331	0.013
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.013
protein ubiquitination	GO:0016567	118	0.013
ribonucleoside catabolic process	GO:0042454	332	0.013
purine ribonucleotide catabolic process	GO:0009154	327	0.013
single organism reproductive process	GO:0044702	159	0.013
nucleotide catabolic process	GO:0009166	330	0.013
mrna metabolic process	GO:0016071	269	0.013
mitotic chromosome condensation	GO:0007076	11	0.013
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.013
purine nucleotide catabolic process	GO:0006195	328	0.013
regulation of protein depolymerization	GO:1901879	12	0.012	Fly
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	38	0.012
intracellular protein transport	GO:0006886	319	0.012
telomere maintenance	GO:0000723	74	0.012
mitotic dna integrity checkpoint	GO:0044774	18	0.012
cellular component morphogenesis	GO:0032989	97	0.012
organelle transport along microtubule	GO:0072384	18	0.012
response to hypoxia	GO:0001666	4	0.012
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.012
mating type determination	GO:0007531	32	0.012
membrane organization	GO:0061024	276	0.012
dna unwinding involved in dna replication	GO:0006268	13	0.012
multi organism reproductive process	GO:0044703	216	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.012
multi organism cellular process	GO:0044764	120	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.011
purine nucleoside monophosphate metabolic process	GO:0009126	262	0.011
cellular developmental process	GO:0048869	191	0.011	Fly
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.011
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.011
regulation of localization	GO:0032879	127	0.011
establishment of mitotic spindle orientation	GO:0000132	10	0.011
positive regulation of transcription dna templated	GO:0045893	286	0.011
positive regulation of catabolic process	GO:0009896	135	0.011
mrna processing	GO:0006397	185	0.011
microtubule based transport	GO:0010970	18	0.011
organelle disassembly	GO:1903008	13	0.011
endomembrane system organization	GO:0010256	74	0.011	Fly
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.011
dna duplex unwinding	GO:0032508	42	0.011
regulation of cellular localization	GO:0060341	50	0.011
protein modification by small protein conjugation or removal	GO:0070647	172	0.010
positive regulation of gene expression	GO:0010628	321	0.010
maintenance of sister chromatid cohesion	GO:0034086	4	0.010
cellular response to oxidative stress	GO:0034599	94	0.010
nuclear migration	GO:0007097	22	0.010
positive regulation of protein metabolic process	GO:0051247	93	0.010
regulation of phosphorus metabolic process	GO:0051174	230	0.010
nuclear migration along microtubule	GO:0030473	18	0.010
regulation of phosphate metabolic process	GO:0019220	230	0.010
single organism membrane organization	GO:0044802	275	0.010

KIP1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease	DO term ID	Probability
disease of cellular proliferation	DOID:14566	0.011
organ system cancer	DOID:0050686	0.011
cancer	DOID:162	0.011

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