IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

40 known processes

ILS1 (YBL076C)

Ils1p

SGD: S000000172
Entrez: 852202
UniProtKB: P09436

Process Predictions
Disease Predictions

ILS1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
amino acid activation	GO:0043038	35	0.994
trna aminoacylation	GO:0043039	35	0.960
trna aminoacylation for protein translation	GO:0006418	32	0.944
translation	GO:0006412	230	0.460
carboxylic acid metabolic process	GO:0019752	338	0.342
organic acid metabolic process	GO:0006082	352	0.315
trna metabolic process	GO:0006399	151	0.304
rrna metabolic process	GO:0016072	244	0.304
cellular amino acid metabolic process	GO:0006520	225	0.295
oxoacid metabolic process	GO:0043436	351	0.252
cytoplasmic translation	GO:0002181	65	0.248
response to abiotic stimulus	GO:0009628	159	0.189
monosaccharide metabolic process	GO:0005996	83	0.163
mitochondrion organization	GO:0007005	261	0.158
single organism carbohydrate metabolic process	GO:0044723	237	0.142
membrane organization	GO:0061024	276	0.134
single organism membrane organization	GO:0044802	275	0.124
carboxylic acid biosynthetic process	GO:0046394	152	0.118
positive regulation of macromolecule metabolic process	GO:0010604	394	0.114
response to pheromone	GO:0019236	92	0.091
ribonucleoprotein complex subunit organization	GO:0071826	152	0.089
maturation of 5 8s rrna from tricistronic rrna transcript ssu rrna 5 8s rrna lsu rrna	GO:0000466	80	0.080
response to external stimulus	GO:0009605	158	0.079
small molecule biosynthetic process	GO:0044283	258	0.076
carbohydrate metabolic process	GO:0005975	252	0.074
developmental process	GO:0032502	261	0.071	Human
hexose metabolic process	GO:0019318	78	0.067
signal transduction	GO:0007165	208	0.065
detection of stimulus	GO:0051606	4	0.064
trna aminoacylation for mitochondrial protein translation	GO:0070127	9	0.058
nucleotide biosynthetic process	GO:0009165	79	0.057
ribonucleoprotein complex assembly	GO:0022618	143	0.056
positive regulation of cellular biosynthetic process	GO:0031328	336	0.053
nuclear transport	GO:0051169	165	0.053
regulation of biological quality	GO:0065008	391	0.052
cell communication	GO:0007154	345	0.052
reproductive process	GO:0022414	248	0.050
cellular response to pheromone	GO:0071444	88	0.049
cellular carbohydrate metabolic process	GO:0044262	135	0.047
nucleotide metabolic process	GO:0009117	453	0.045
multi organism process	GO:0051704	233	0.045
cellular amino acid biosynthetic process	GO:0008652	118	0.043
signaling	GO:0023052	208	0.042
dna templated transcription termination	GO:0006353	42	0.041
positive regulation of gene expression	GO:0010628	321	0.040
organic acid biosynthetic process	GO:0016053	152	0.040
mrna processing	GO:0006397	185	0.039
response to chemical	GO:0042221	390	0.039
posttranscriptional regulation of gene expression	GO:0010608	115	0.038
positive regulation of rna biosynthetic process	GO:1902680	286	0.037
alpha amino acid metabolic process	GO:1901605	124	0.037
nucleoside phosphate biosynthetic process	GO:1901293	80	0.037
single organism signaling	GO:0044700	208	0.036
glucose catabolic process	GO:0006007	17	0.035
dna packaging	GO:0006323	55	0.035
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.034
negative regulation of transcription dna templated	GO:0045892	258	0.034
organophosphate metabolic process	GO:0019637	597	0.034
regulation of cell communication	GO:0010646	124	0.034
anatomical structure development	GO:0048856	160	0.033
protein targeting to er	GO:0045047	39	0.033
multi organism reproductive process	GO:0044703	216	0.033
positive regulation of biosynthetic process	GO:0009891	336	0.032
conjugation with cellular fusion	GO:0000747	106	0.032
chromatin assembly	GO:0031497	35	0.031
rrna processing	GO:0006364	227	0.029
cellular response to external stimulus	GO:0071496	150	0.029
multi organism cellular process	GO:0044764	120	0.028
nucleobase containing small molecule metabolic process	GO:0055086	491	0.026
nitrogen compound transport	GO:0071705	212	0.026
positive regulation of rna metabolic process	GO:0051254	294	0.025
cellular protein complex assembly	GO:0043623	209	0.025
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.025
negative regulation of rna metabolic process	GO:0051253	262	0.025
single organism developmental process	GO:0044767	258	0.024	Human
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.024
intracellular signal transduction	GO:0035556	112	0.024
conjugation	GO:0000746	107	0.024
single organism catabolic process	GO:0044712	619	0.023
establishment of protein localization to endoplasmic reticulum	GO:0072599	40	0.023
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.023
ncrna processing	GO:0034470	330	0.023
nucleoside metabolic process	GO:0009116	394	0.023
protein folding	GO:0006457	94	0.023
macromolecule catabolic process	GO:0009057	383	0.022
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.022
nucleoside phosphate metabolic process	GO:0006753	458	0.021
establishment of organelle localization	GO:0051656	96	0.021
cell wall organization or biogenesis	GO:0071554	190	0.021
ion homeostasis	GO:0050801	118	0.020
cellular response to organic substance	GO:0071310	159	0.020
cellular protein complex disassembly	GO:0043624	42	0.020
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.020
cellular amide metabolic process	GO:0043603	59	0.020
fungal type cell wall organization	GO:0031505	145	0.020
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.020
nuclear export	GO:0051168	124	0.019
detection of chemical stimulus	GO:0009593	3	0.019
regulation of molecular function	GO:0065009	320	0.019
cellular response to starvation	GO:0009267	90	0.019
aspartate family amino acid metabolic process	GO:0009066	40	0.019
cellular cation homeostasis	GO:0030003	100	0.019
cellular response to chemical stimulus	GO:0070887	315	0.018
ion transport	GO:0006811	274	0.018
chromatin silencing at telomere	GO:0006348	84	0.018
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.018
regulation of translational elongation	GO:0006448	25	0.018
organonitrogen compound biosynthetic process	GO:1901566	314	0.018
purine containing compound biosynthetic process	GO:0072522	53	0.018
pigment biosynthetic process	GO:0046148	22	0.018
negative regulation of rna biosynthetic process	GO:1902679	260	0.018
regulation of signal transduction	GO:0009966	114	0.018
cellular homeostasis	GO:0019725	138	0.017
carbohydrate biosynthetic process	GO:0016051	82	0.017
nucleotide catabolic process	GO:0009166	330	0.017
negative regulation of gene expression epigenetic	GO:0045814	147	0.017
regulation of response to stimulus	GO:0048583	157	0.017
vesicle organization	GO:0016050	68	0.017
membrane invagination	GO:0010324	43	0.017
single organism membrane invagination	GO:1902534	43	0.016
vesicle mediated transport	GO:0016192	335	0.016
maturation of 5 8s rrna	GO:0000460	80	0.016
cellular response to nutrient levels	GO:0031669	144	0.016
vitamin metabolic process	GO:0006766	41	0.016
pigment metabolic process	GO:0042440	23	0.016
monosaccharide catabolic process	GO:0046365	28	0.016
mrna splicing via spliceosome	GO:0000398	108	0.015
ribosome assembly	GO:0042255	57	0.015
cellular developmental process	GO:0048869	191	0.015	Human
anatomical structure morphogenesis	GO:0009653	160	0.015
pseudouridine synthesis	GO:0001522	13	0.015
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.015
dna conformation change	GO:0071103	98	0.015
macromolecular complex disassembly	GO:0032984	80	0.015
energy derivation by oxidation of organic compounds	GO:0015980	125	0.015
response to starvation	GO:0042594	96	0.015
adaptation of signaling pathway	GO:0023058	23	0.015
purine ribonucleotide catabolic process	GO:0009154	327	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.014
nucleoside monophosphate metabolic process	GO:0009123	267	0.014
regulation of protein metabolic process	GO:0051246	237	0.014
negative regulation of biosynthetic process	GO:0009890	312	0.014
cellular ketone metabolic process	GO:0042180	63	0.014
negative regulation of cellular biosynthetic process	GO:0031327	312	0.014
cellular nitrogen compound catabolic process	GO:0044270	494	0.014
response to nutrient levels	GO:0031667	150	0.014
rna localization	GO:0006403	112	0.014
carbohydrate derivative catabolic process	GO:1901136	339	0.014
atp catabolic process	GO:0006200	224	0.013
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.013
generation of precursor metabolites and energy	GO:0006091	147	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.013
positive regulation of molecular function	GO:0044093	185	0.013
rrna modification	GO:0000154	19	0.013
rna export from nucleus	GO:0006405	88	0.013
lipid transport	GO:0006869	58	0.013
water soluble vitamin metabolic process	GO:0006767	41	0.012
carbohydrate catabolic process	GO:0016052	77	0.012
mitochondrial rna metabolic process	GO:0000959	24	0.012
death	GO:0016265	30	0.012
organelle localization	GO:0051640	128	0.012
response to extracellular stimulus	GO:0009991	156	0.012
response to inorganic substance	GO:0010035	47	0.012
vitamin biosynthetic process	GO:0009110	38	0.012
establishment of rna localization	GO:0051236	92	0.012
phospholipid metabolic process	GO:0006644	125	0.012
purine ribonucleoside monophosphate catabolic process	GO:0009169	224	0.012
transmembrane transport	GO:0055085	349	0.012
regulation of organelle organization	GO:0033043	243	0.012
cellular divalent inorganic cation homeostasis	GO:0072503	21	0.012
organonitrogen compound catabolic process	GO:1901565	404	0.012
developmental process involved in reproduction	GO:0003006	159	0.012
chromatin modification	GO:0016568	200	0.011
positive regulation of phosphate metabolic process	GO:0045937	147	0.011
golgi vesicle transport	GO:0048193	188	0.011
nucleic acid transport	GO:0050657	94	0.011
lipid localization	GO:0010876	60	0.011
ribonucleoside monophosphate catabolic process	GO:0009158	224	0.011
srp dependent cotranslational protein targeting to membrane	GO:0006614	14	0.011
purine ribonucleoside biosynthetic process	GO:0046129	31	0.011
mrna metabolic process	GO:0016071	269	0.011
endomembrane system organization	GO:0010256	74	0.011
purine nucleoside monophosphate catabolic process	GO:0009128	224	0.011
protein complex assembly	GO:0006461	302	0.011
cellular response to extracellular stimulus	GO:0031668	150	0.011
protein complex disassembly	GO:0043241	70	0.011
purine nucleoside biosynthetic process	GO:0042451	31	0.011
protein processing	GO:0016485	64	0.011
negative regulation of gene expression	GO:0010629	312	0.011
sexual reproduction	GO:0019953	216	0.011
negative regulation of cellular metabolic process	GO:0031324	407	0.010
cation transport	GO:0006812	166	0.010
nucleocytoplasmic transport	GO:0006913	163	0.010
chromatin silencing	GO:0006342	147	0.010
atp metabolic process	GO:0046034	251	0.010
positive regulation of catabolic process	GO:0009896	135	0.010
polysaccharide metabolic process	GO:0005976	60	0.010
external encapsulating structure organization	GO:0045229	146	0.010
mitochondrial transport	GO:0006839	76	0.010
programmed cell death	GO:0012501	30	0.010

ILS1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.036
	nervous system disease	DOID:863	0	0.018

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