IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

23 known processes

FTH1 (YBR207W)

Fth1p

Entrez: 852506
SGD: S000000411
UniProtKB: P38310

Process Predictions
Disease Predictions

FTH1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
transmembrane transport	GO:0055085	349	0.987
metal ion transport	GO:0030001	75	0.963
inorganic ion transmembrane transport	GO:0098660	109	0.962
inorganic cation transmembrane transport	GO:0098662	98	0.960
cation transmembrane transport	GO:0098655	135	0.902
ion transport	GO:0006811	274	0.863
cation transport	GO:0006812	166	0.858
ion transmembrane transport	GO:0034220	200	0.773
transition metal ion transport	GO:0000041	45	0.633
cellular divalent inorganic cation homeostasis	GO:0072503	21	0.508
transition metal ion homeostasis	GO:0055076	59	0.456
divalent inorganic cation homeostasis	GO:0072507	21	0.403
cellular ion homeostasis	GO:0006873	112	0.382
ion homeostasis	GO:0050801	118	0.369
zinc ion transport	GO:0006829	9	0.362
cation homeostasis	GO:0055080	105	0.313
metal ion homeostasis	GO:0055065	79	0.304
chemical homeostasis	GO:0048878	137	0.286
cellular transition metal ion homeostasis	GO:0046916	59	0.269
cellular metal ion homeostasis	GO:0006875	78	0.237
regulation of biological quality	GO:0065008	391	0.233
organic cyclic compound catabolic process	GO:1901361	499	0.218
signaling	GO:0023052	208	0.205
single organism catabolic process	GO:0044712	619	0.196
protein transport	GO:0015031	345	0.193
membrane organization	GO:0061024	276	0.180
response to chemical	GO:0042221	390	0.166
organic acid metabolic process	GO:0006082	352	0.160
aromatic compound catabolic process	GO:0019439	491	0.148
phosphorylation	GO:0016310	291	0.134
oxoacid metabolic process	GO:0043436	351	0.125
cellular cation homeostasis	GO:0030003	100	0.117
intracellular protein transport	GO:0006886	319	0.116
organic anion transport	GO:0015711	114	0.104
divalent metal ion transport	GO:0070838	17	0.101
negative regulation of cell communication	GO:0010648	33	0.101
negative regulation of cellular component organization	GO:0051129	109	0.101
cellular response to chemical stimulus	GO:0070887	315	0.100
atp metabolic process	GO:0046034	251	0.100
cellular chemical homeostasis	GO:0055082	123	0.096
response to oxygen containing compound	GO:1901700	61	0.084
regulation of nuclear division	GO:0051783	103	0.083
cellular homeostasis	GO:0019725	138	0.081
heterocycle catabolic process	GO:0046700	494	0.080
protein localization to organelle	GO:0033365	337	0.077
ribonucleoside metabolic process	GO:0009119	389	0.077
purine nucleoside monophosphate metabolic process	GO:0009126	262	0.076
divalent inorganic cation transport	GO:0072511	26	0.075
response to organic substance	GO:0010033	182	0.071
negative regulation of signaling	GO:0023057	30	0.070
nucleobase containing compound transport	GO:0015931	124	0.069
glycosyl compound catabolic process	GO:1901658	335	0.068
regulation of cellular component organization	GO:0051128	334	0.065
cellular nitrogen compound catabolic process	GO:0044270	494	0.063
nucleoside metabolic process	GO:0009116	394	0.063
nucleoside monophosphate metabolic process	GO:0009123	267	0.062
homeostatic process	GO:0042592	227	0.061
regulation of cell communication	GO:0010646	124	0.061
establishment of protein localization	GO:0045184	367	0.061
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.060
glycosyl compound metabolic process	GO:1901657	398	0.055
regulation of transport	GO:0051049	85	0.053
cellular zinc ion homeostasis	GO:0006882	10	0.053
nucleoside catabolic process	GO:0009164	335	0.052
alpha amino acid biosynthetic process	GO:1901607	91	0.052
nucleobase containing compound catabolic process	GO:0034655	479	0.052
regulation of signaling	GO:0023051	119	0.050
regulation of molecular function	GO:0065009	320	0.049
regulation of cellular protein metabolic process	GO:0032268	232	0.047
ncrna processing	GO:0034470	330	0.047
zinc ion homeostasis	GO:0055069	10	0.046
carbohydrate derivative catabolic process	GO:1901136	339	0.045
maintenance of location	GO:0051235	66	0.043
regulation of phosphorus metabolic process	GO:0051174	230	0.043
anion transport	GO:0006820	145	0.042
monosaccharide transport	GO:0015749	24	0.041
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.041
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.041
negative regulation of cellular metabolic process	GO:0031324	407	0.040
nucleotide metabolic process	GO:0009117	453	0.040
protein targeting	GO:0006605	272	0.039
nucleoside monophosphate catabolic process	GO:0009125	224	0.039
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.039
nucleotide catabolic process	GO:0009166	330	0.039
anion transmembrane transport	GO:0098656	79	0.038
nucleoside triphosphate metabolic process	GO:0009141	364	0.038
purine nucleoside monophosphate catabolic process	GO:0009128	224	0.036
carboxylic acid metabolic process	GO:0019752	338	0.036
regulation of transferase activity	GO:0051338	83	0.036
nucleoside phosphate catabolic process	GO:1901292	331	0.035
copper ion transport	GO:0006825	16	0.034
purine ribonucleoside catabolic process	GO:0046130	330	0.034
regulation of anatomical structure size	GO:0090066	50	0.033
macromolecule catabolic process	GO:0009057	383	0.033
nucleobase containing small molecule metabolic process	GO:0055086	491	0.032
multi organism process	GO:0051704	233	0.032
proteolysis	GO:0006508	268	0.032
positive regulation of macromolecule metabolic process	GO:0010604	394	0.032
nitrogen compound transport	GO:0071705	212	0.030
cellular response to organic substance	GO:0071310	159	0.030
regulation of localization	GO:0032879	127	0.030
organic acid catabolic process	GO:0016054	71	0.029
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.029
regulation of cellular component size	GO:0032535	50	0.029
organophosphate catabolic process	GO:0046434	338	0.029
establishment of protein localization to organelle	GO:0072594	278	0.028
cellular response to extracellular stimulus	GO:0031668	150	0.028
indole containing compound metabolic process	GO:0042430	9	0.027
conjugation with cellular fusion	GO:0000747	106	0.027
cell communication	GO:0007154	345	0.026
purine containing compound metabolic process	GO:0072521	400	0.026
single organism membrane organization	GO:0044802	275	0.025
negative regulation of biosynthetic process	GO:0009890	312	0.025
atp catabolic process	GO:0006200	224	0.025
response to inorganic substance	GO:0010035	47	0.025
purine ribonucleotide catabolic process	GO:0009154	327	0.024
negative regulation of gene expression	GO:0010629	312	0.024
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.023
single organism signaling	GO:0044700	208	0.023
protein catabolic process	GO:0030163	221	0.022
carbohydrate transport	GO:0008643	33	0.022
carbohydrate derivative metabolic process	GO:1901135	549	0.022
detection of hexose stimulus	GO:0009732	3	0.022
organonitrogen compound biosynthetic process	GO:1901566	314	0.021
purine nucleoside metabolic process	GO:0042278	380	0.021
protein targeting to vacuole	GO:0006623	91	0.021
detection of stimulus	GO:0051606	4	0.020
cellular response to pheromone	GO:0071444	88	0.020
protein maturation	GO:0051604	76	0.020
organonitrogen compound catabolic process	GO:1901565	404	0.019
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.019
cellular response to nutrient levels	GO:0031669	144	0.018
organophosphate ester transport	GO:0015748	45	0.018
vacuolar transport	GO:0007034	145	0.018
autophagy	GO:0006914	106	0.017
glycoprotein biosynthetic process	GO:0009101	61	0.017
regulation of protein modification process	GO:0031399	110	0.017
detection of monosaccharide stimulus	GO:0034287	3	0.017
negative regulation of intracellular signal transduction	GO:1902532	27	0.016
single organism membrane invagination	GO:1902534	43	0.016
positive regulation of molecular function	GO:0044093	185	0.016
response to toxic substance	GO:0009636	9	0.016
purine nucleotide catabolic process	GO:0006195	328	0.016
meiotic cell cycle	GO:0051321	272	0.016
positive regulation of cellular protein metabolic process	GO:0032270	89	0.016
small molecule catabolic process	GO:0044282	88	0.016
negative regulation of nuclear division	GO:0051784	62	0.015
nucleoside triphosphate catabolic process	GO:0009143	329	0.015
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.015
establishment of protein localization to vacuole	GO:0072666	91	0.015
regulation of cellular amino acid metabolic process	GO:0006521	16	0.015
regulation of cell size	GO:0008361	30	0.015
negative regulation of organelle organization	GO:0010639	103	0.015
response to nutrient levels	GO:0031667	150	0.015
fungal type cell wall assembly	GO:0071940	53	0.014
aerobic respiration	GO:0009060	55	0.014
anatomical structure development	GO:0048856	160	0.014
regulation of protein metabolic process	GO:0051246	237	0.014
regulation of protein phosphorylation	GO:0001932	75	0.014
regulation of cell cycle	GO:0051726	195	0.014
peptidyl amino acid modification	GO:0018193	116	0.014
cellular component morphogenesis	GO:0032989	97	0.014
response to organic cyclic compound	GO:0014070	1	0.014
iron ion homeostasis	GO:0055072	34	0.014
response to metal ion	GO:0010038	24	0.014
ribonucleoside monophosphate catabolic process	GO:0009158	224	0.014
hexose transport	GO:0008645	24	0.013
microautophagy	GO:0016237	43	0.013
trna processing	GO:0008033	101	0.013
purine nucleoside catabolic process	GO:0006152	330	0.013
positive regulation of ion transport	GO:0043270	5	0.013
negative regulation of catalytic activity	GO:0043086	60	0.013
spore wall biogenesis	GO:0070590	52	0.013
cellular response to oxygen containing compound	GO:1901701	43	0.013
single organism cellular localization	GO:1902580	375	0.013
regulation of phosphorylation	GO:0042325	86	0.013
regulation of catalytic activity	GO:0050790	307	0.013
regulation of cellular amine metabolic process	GO:0033238	21	0.013
positive regulation of apoptotic process	GO:0043065	3	0.013
positive regulation of protein modification process	GO:0031401	49	0.013
regulation of organelle organization	GO:0033043	243	0.013
dna replication	GO:0006260	147	0.012
reproductive process	GO:0022414	248	0.012
alpha amino acid metabolic process	GO:1901605	124	0.012
mitotic sister chromatid segregation	GO:0000070	85	0.012
regulation of response to stimulus	GO:0048583	157	0.012
cell division	GO:0051301	205	0.011
regulation of cell cycle process	GO:0010564	150	0.011
vacuole organization	GO:0007033	75	0.011
regulation of meiosis	GO:0040020	42	0.011
programmed cell death	GO:0012501	30	0.011
negative regulation of cellular protein metabolic process	GO:0032269	85	0.011
purine ribonucleotide metabolic process	GO:0009150	372	0.011
negative regulation of signal transduction	GO:0009968	30	0.011
positive regulation of catalytic activity	GO:0043085	178	0.011
mitochondrial translation	GO:0032543	52	0.011
organic hydroxy compound transport	GO:0015850	41	0.011
negative regulation of macromolecule metabolic process	GO:0010605	375	0.011
conjugation	GO:0000746	107	0.011
amine metabolic process	GO:0009308	51	0.010
external encapsulating structure organization	GO:0045229	146	0.010
cellular amino acid metabolic process	GO:0006520	225	0.010

FTH1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.026

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