IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

31 known processes

PBP2 (YBR233W)

Pbp2p

(Aliases: HEK1)

Entrez: 852533
SGD: S000000437
UniProtKB: P38151

Process Predictions
Disease Predictions

PBP2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
meiotic nuclear division	GO:0007126	163	0.512
meiosis i	GO:0007127	92	0.509
meiotic cell cycle	GO:0051321	272	0.367
reciprocal dna recombination	GO:0035825	54	0.260
mrna metabolic process	GO:0016071	269	0.242
reciprocal meiotic recombination	GO:0007131	54	0.242
meiotic cell cycle process	GO:1903046	229	0.182
dna recombination	GO:0006310	172	0.174
mrna processing	GO:0006397	185	0.168
dna conformation change	GO:0071103	98	0.112
developmental process	GO:0032502	261	0.109
reproduction of a single celled organism	GO:0032505	191	0.109
organelle fission	GO:0048285	272	0.103
nuclear division	GO:0000280	263	0.096
anatomical structure development	GO:0048856	160	0.092
sexual reproduction	GO:0019953	216	0.092
single organism developmental process	GO:0044767	258	0.086
rna 3 end processing	GO:0031123	88	0.082
regulation of cell division	GO:0051302	113	0.076
nucleobase containing compound catabolic process	GO:0034655	479	0.070
positive regulation of macromolecule metabolic process	GO:0010604	394	0.066
nuclear transport	GO:0051169	165	0.066
regulation of protein metabolic process	GO:0051246	237	0.062
nucleocytoplasmic transport	GO:0006913	163	0.058
regulation of molecular function	GO:0065009	320	0.057
mrna 3 end processing	GO:0031124	54	0.056
organic cyclic compound catabolic process	GO:1901361	499	0.055
heterocycle catabolic process	GO:0046700	494	0.054
regulation of cellular component organization	GO:0051128	334	0.051
cell division	GO:0051301	205	0.050
conjugation	GO:0000746	107	0.049
cellular nitrogen compound catabolic process	GO:0044270	494	0.048
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.047
meiotic chromosome segregation	GO:0045132	31	0.047
membrane organization	GO:0061024	276	0.047
aromatic compound catabolic process	GO:0019439	491	0.047
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.047
establishment of protein localization to organelle	GO:0072594	278	0.046
chromosome organization involved in meiosis	GO:0070192	32	0.046
rrna metabolic process	GO:0016072	244	0.046
organophosphate metabolic process	GO:0019637	597	0.045
multi organism reproductive process	GO:0044703	216	0.045
mrna export from nucleus	GO:0006406	60	0.044
regulation of cellular protein metabolic process	GO:0032268	232	0.044
cellular developmental process	GO:0048869	191	0.043
conjugation with cellular fusion	GO:0000747	106	0.043
reproductive process	GO:0022414	248	0.040
regulation of nuclear division	GO:0051783	103	0.040
regulation of organelle organization	GO:0033043	243	0.039
mitotic cell cycle	GO:0000278	306	0.039
carbohydrate derivative metabolic process	GO:1901135	549	0.039
protein modification by small protein conjugation	GO:0032446	144	0.038
intracellular protein transport	GO:0006886	319	0.038
single organism catabolic process	GO:0044712	619	0.038
response to chemical	GO:0042221	390	0.037
methylation	GO:0032259	101	0.037
regulation of cell cycle process	GO:0010564	150	0.037
cytoskeleton organization	GO:0007010	230	0.037
translation	GO:0006412	230	0.035
nuclear export	GO:0051168	124	0.035
positive regulation of transcription dna templated	GO:0045893	286	0.033
nuclear transcribed mrna catabolic process	GO:0000956	89	0.033
negative regulation of mitosis	GO:0045839	39	0.033
regulation of catalytic activity	GO:0050790	307	0.033
regulation of cellular component biogenesis	GO:0044087	112	0.033
negative regulation of cell cycle	GO:0045786	91	0.033
multi organism cellular process	GO:0044764	120	0.033
dna packaging	GO:0006323	55	0.033
anatomical structure morphogenesis	GO:0009653	160	0.032
reproductive process in single celled organism	GO:0022413	145	0.032
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.032
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.032
nucleoside metabolic process	GO:0009116	394	0.032
nucleoside phosphate metabolic process	GO:0006753	458	0.032
protein phosphorylation	GO:0006468	197	0.032
regulation of biological quality	GO:0065008	391	0.032
positive regulation of gene expression	GO:0010628	321	0.031
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.030
protein transport	GO:0015031	345	0.030
posttranscriptional regulation of gene expression	GO:0010608	115	0.030	Yeast
regulation of mitotic cell cycle	GO:0007346	107	0.030
cellular macromolecule catabolic process	GO:0044265	363	0.029
fungal type cell wall organization	GO:0031505	145	0.029
rna catabolic process	GO:0006401	118	0.029
protein modification by small protein conjugation or removal	GO:0070647	172	0.029
dna repair	GO:0006281	236	0.029
recombinational repair	GO:0000725	64	0.029
mitotic cell cycle checkpoint	GO:0007093	56	0.028
rna polyadenylation	GO:0043631	26	0.028
sporulation	GO:0043934	132	0.027
ribose phosphate metabolic process	GO:0019693	384	0.027
cellular response to chemical stimulus	GO:0070887	315	0.026
nucleotide metabolic process	GO:0009117	453	0.026
cell cycle g2 m phase transition	GO:0044839	39	0.026
nucleobase containing small molecule metabolic process	GO:0055086	491	0.026
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.025
regulation of cell cycle	GO:0051726	195	0.025
regulation of cell cycle phase transition	GO:1901987	70	0.025
glycosyl compound catabolic process	GO:1901658	335	0.025
glycosyl compound metabolic process	GO:1901657	398	0.024
positive regulation of rna metabolic process	GO:0051254	294	0.024
response to cell cycle checkpoint signaling	GO:0072396	8	0.024
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.024
positive regulation of biosynthetic process	GO:0009891	336	0.024
purine nucleoside metabolic process	GO:0042278	380	0.024
regulation of mitosis	GO:0007088	65	0.024
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.023
synapsis	GO:0007129	19	0.023
single organism membrane organization	GO:0044802	275	0.023
mitotic nuclear division	GO:0007067	131	0.023
macromolecular complex disassembly	GO:0032984	80	0.023
mrna transport	GO:0051028	60	0.023
protein targeting to nucleus	GO:0044744	57	0.022
cell cycle checkpoint	GO:0000075	82	0.022
positive regulation of protein modification process	GO:0031401	49	0.022
multi organism process	GO:0051704	233	0.022
ribonucleotide metabolic process	GO:0009259	377	0.022
glycerolipid biosynthetic process	GO:0045017	71	0.022
glycerophospholipid biosynthetic process	GO:0046474	68	0.022
protein localization to organelle	GO:0033365	337	0.022
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.022
rna localization	GO:0006403	112	0.021	Yeast
regulation of cellular catabolic process	GO:0031329	195	0.021
dna integrity checkpoint	GO:0031570	41	0.021
vacuolar transport	GO:0007034	145	0.021
cell cycle phase transition	GO:0044770	144	0.020
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.020
mitotic cell cycle phase transition	GO:0044772	141	0.020
cellular transition metal ion homeostasis	GO:0046916	59	0.020
regulation of translation	GO:0006417	89	0.020
pseudohyphal growth	GO:0007124	75	0.020
positive regulation of catalytic activity	GO:0043085	178	0.020
cellular component disassembly	GO:0022411	86	0.020
single organism membrane fusion	GO:0044801	71	0.020
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.020
positive regulation of cell death	GO:0010942	3	0.020
regulation of metaphase anaphase transition of cell cycle	GO:1902099	27	0.020
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.019
positive regulation of cellular protein metabolic process	GO:0032270	89	0.019
response to oxidative stress	GO:0006979	99	0.019
protein dna complex subunit organization	GO:0071824	153	0.019
endomembrane system organization	GO:0010256	74	0.019
positive regulation of cellular biosynthetic process	GO:0031328	336	0.019
negative regulation of cellular catabolic process	GO:0031330	43	0.019
chemical homeostasis	GO:0048878	137	0.018
purine nucleotide catabolic process	GO:0006195	328	0.018
negative regulation of gene expression	GO:0010629	312	0.018
nucleoside monophosphate metabolic process	GO:0009123	267	0.018
regulation of protein modification process	GO:0031399	110	0.018
ribonucleoside metabolic process	GO:0009119	389	0.018
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.018
purine ribonucleoside metabolic process	GO:0046128	380	0.018
nucleotide catabolic process	GO:0009166	330	0.018
response to abiotic stimulus	GO:0009628	159	0.017
chromatin remodeling	GO:0006338	80	0.017
regulation of meiosis i	GO:0060631	14	0.017
negative regulation of catabolic process	GO:0009895	43	0.017
establishment of protein localization	GO:0045184	367	0.017
modification dependent macromolecule catabolic process	GO:0043632	203	0.017
macromolecule methylation	GO:0043414	85	0.017
purine containing compound metabolic process	GO:0072521	400	0.017
cell communication	GO:0007154	345	0.017
purine ribonucleotide catabolic process	GO:0009154	327	0.016
cell differentiation	GO:0030154	161	0.016
purine nucleotide metabolic process	GO:0006163	376	0.016
vacuole organization	GO:0007033	75	0.016
regulation of catabolic process	GO:0009894	199	0.016
fungal type cell wall organization or biogenesis	GO:0071852	169	0.016
ribonucleotide catabolic process	GO:0009261	327	0.016
filamentous growth of a population of unicellular organisms	GO:0044182	109	0.016
macromolecule catabolic process	GO:0009057	383	0.016
cell development	GO:0048468	107	0.016
negative regulation of macromolecule metabolic process	GO:0010605	375	0.016
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.016
cellular response to dna damage stimulus	GO:0006974	287	0.016
protein import	GO:0017038	122	0.016
regulation of dna replication	GO:0006275	51	0.015
response to organic cyclic compound	GO:0014070	1	0.015
protein import into nucleus	GO:0006606	55	0.015
mitotic cell cycle process	GO:1903047	294	0.015
positive regulation of apoptotic process	GO:0043065	3	0.015
regulation of protein modification by small protein conjugation or removal	GO:1903320	29	0.015
cellular modified amino acid metabolic process	GO:0006575	51	0.015
external encapsulating structure organization	GO:0045229	146	0.015
snrna metabolic process	GO:0016073	25	0.015
homeostatic process	GO:0042592	227	0.015
nucleoside monophosphate catabolic process	GO:0009125	224	0.015
dna dependent dna replication	GO:0006261	115	0.015
regulation of cellular amine metabolic process	GO:0033238	21	0.015
protein targeting	GO:0006605	272	0.015
nuclear transcribed mrna poly a tail shortening	GO:0000289	14	0.015
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	109	0.015
negative regulation of protein metabolic process	GO:0051248	85	0.015
ion homeostasis	GO:0050801	118	0.014
positive regulation of translation	GO:0045727	34	0.014
negative regulation of cell cycle phase transition	GO:1901988	59	0.014
ribonucleoside catabolic process	GO:0042454	332	0.014
protein methylation	GO:0006479	48	0.014
positive regulation of molecular function	GO:0044093	185	0.014
regulation of cellular localization	GO:0060341	50	0.014
positive regulation of programmed cell death	GO:0043068	3	0.014
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.014
cellular chemical homeostasis	GO:0055082	123	0.014
negative regulation of catalytic activity	GO:0043086	60	0.014
nucleoside phosphate catabolic process	GO:1901292	331	0.014
carbohydrate derivative catabolic process	GO:1901136	339	0.014
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.014
single organism cellular localization	GO:1902580	375	0.014
ascospore formation	GO:0030437	107	0.014
positive regulation of intracellular transport	GO:0032388	4	0.013
positive regulation of catabolic process	GO:0009896	135	0.013
organonitrogen compound catabolic process	GO:1901565	404	0.013
phospholipid biosynthetic process	GO:0008654	89	0.013
protein alkylation	GO:0008213	48	0.013
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.013
mitotic recombination	GO:0006312	55	0.013
peptidyl amino acid modification	GO:0018193	116	0.013
organonitrogen compound biosynthetic process	GO:1901566	314	0.013
negative regulation of protein processing	GO:0010955	33	0.013
positive regulation of organelle organization	GO:0010638	85	0.013
nitrogen compound transport	GO:0071705	212	0.013
organophosphate catabolic process	GO:0046434	338	0.013
purine nucleoside catabolic process	GO:0006152	330	0.013
sister chromatid segregation	GO:0000819	93	0.013
negative regulation of chromosome organization	GO:2001251	39	0.013
positive regulation of protein metabolic process	GO:0051247	93	0.013
nucleoside triphosphate catabolic process	GO:0009143	329	0.013
cellular amine metabolic process	GO:0044106	51	0.013
rna splicing via transesterification reactions	GO:0000375	118	0.013
dna replication initiation	GO:0006270	48	0.013
response to organic substance	GO:0010033	182	0.013
negative regulation of molecular function	GO:0044092	68	0.013
purine containing compound catabolic process	GO:0072523	332	0.013
regulation of chromosome organization	GO:0033044	66	0.013
positive regulation of dna templated transcription elongation	GO:0032786	42	0.013
regulation of protein localization	GO:0032880	62	0.013
glycerophospholipid metabolic process	GO:0006650	98	0.013
phosphatidylcholine biosynthetic process	GO:0006656	18	0.013
negative regulation of cell division	GO:0051782	66	0.012
cellular lipid metabolic process	GO:0044255	229	0.012
cofactor biosynthetic process	GO:0051188	80	0.012
purine ribonucleotide metabolic process	GO:0009150	372	0.012
dna catabolic process	GO:0006308	42	0.012
ribonucleoside monophosphate catabolic process	GO:0009158	224	0.012
purine ribonucleoside catabolic process	GO:0046130	330	0.012
guanosine containing compound metabolic process	GO:1901068	111	0.012
cellular component morphogenesis	GO:0032989	97	0.012
mitotic dna integrity checkpoint	GO:0044774	18	0.012
negative regulation of proteolysis	GO:0045861	33	0.012
amine metabolic process	GO:0009308	51	0.012
nucleoside catabolic process	GO:0009164	335	0.012
nuclear import	GO:0051170	57	0.012
regulation of dna metabolic process	GO:0051052	100	0.012
chromatin modification	GO:0016568	200	0.012
negative regulation of phosphate metabolic process	GO:0045936	49	0.012
rna export from nucleus	GO:0006405	88	0.012
nucleic acid phosphodiester bond hydrolysis	GO:0090305	194	0.012
regulation of phosphorus metabolic process	GO:0051174	230	0.012
nucleobase containing compound transport	GO:0015931	124	0.012
negative regulation of cellular protein metabolic process	GO:0032269	85	0.012
regulation of transferase activity	GO:0051338	83	0.012
dna replication	GO:0006260	147	0.011	Yeast
cellular amide metabolic process	GO:0043603	59	0.011
chromatin assembly or disassembly	GO:0006333	60	0.011
metaphase anaphase transition of mitotic cell cycle	GO:0007091	28	0.011
negative regulation of organelle organization	GO:0010639	103	0.011
cell growth	GO:0016049	89	0.011
trna metabolic process	GO:0006399	151	0.011
postreplication repair	GO:0006301	24	0.011
mrna catabolic process	GO:0006402	93	0.011
dephosphorylation	GO:0016311	127	0.011
single organism reproductive process	GO:0044702	159	0.011
membrane fusion	GO:0061025	73	0.011
transition metal ion homeostasis	GO:0055076	59	0.011
single organism nuclear import	GO:1902593	56	0.011
carboxylic acid metabolic process	GO:0019752	338	0.011
regulation of nucleotide catabolic process	GO:0030811	106	0.011
protein maturation	GO:0051604	76	0.011
regulation of protein localization to nucleus	GO:1900180	16	0.011
lipid metabolic process	GO:0006629	269	0.011
regulation of hydrolase activity	GO:0051336	133	0.011
ethanolamine containing compound metabolic process	GO:0042439	21	0.011
negative regulation of protein catabolic process	GO:0042177	27	0.011
ncrna catabolic process	GO:0034661	33	0.011
phosphorylation	GO:0016310	291	0.011
regulation of establishment of protein localization	GO:0070201	17	0.011
negative regulation of cellular metabolic process	GO:0031324	407	0.011
regulation of protein maturation	GO:1903317	34	0.010
negative regulation of proteolysis involved in cellular protein catabolic process	GO:1903051	27	0.010
asexual reproduction	GO:0019954	48	0.010
dna geometric change	GO:0032392	43	0.010
negative regulation of proteasomal protein catabolic process	GO:1901799	25	0.010
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic process	GO:0031145	35	0.010
mitotic sister chromatid separation	GO:0051306	26	0.010
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.010
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.010
negative regulation of cell cycle process	GO:0010948	86	0.010

PBP2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.014

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