IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

20 known processes

MGR1 (YCL044C)

Mgr1p

Entrez: 850313
SGD: S000000549
UniProtKB: P25573

Process Predictions
Disease Predictions

MGR1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.857
proteolysis	GO:0006508	268	0.719
protein catabolic process	GO:0030163	221	0.618
cellular protein catabolic process	GO:0044257	213	0.401
modification dependent macromolecule catabolic process	GO:0043632	203	0.278
mitochondrion organization	GO:0007005	261	0.247
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	137	0.242
cellular lipid metabolic process	GO:0044255	229	0.221
protein processing	GO:0016485	64	0.206
protein complex assembly	GO:0006461	302	0.178
protein maturation	GO:0051604	76	0.168
single organism membrane organization	GO:0044802	275	0.163
single organism cellular localization	GO:1902580	375	0.161
ubiquitin dependent protein catabolic process	GO:0006511	181	0.151
macromolecule catabolic process	GO:0009057	383	0.146
lipid metabolic process	GO:0006629	269	0.138
cellular homeostasis	GO:0019725	138	0.135
membrane organization	GO:0061024	276	0.134
positive regulation of cellular biosynthetic process	GO:0031328	336	0.131
phosphorylation	GO:0016310	291	0.117
response to chemical	GO:0042221	390	0.112
modification dependent protein catabolic process	GO:0019941	181	0.111
misfolded or incompletely synthesized protein catabolic process	GO:0006515	21	0.110
cellular macromolecule catabolic process	GO:0044265	363	0.104
homeostatic process	GO:0042592	227	0.102
protein complex biogenesis	GO:0070271	314	0.098
single organism catabolic process	GO:0044712	619	0.095
purine containing compound metabolic process	GO:0072521	400	0.087
regulation of cellular component organization	GO:0051128	334	0.081
organophosphate metabolic process	GO:0019637	597	0.081
nucleoside phosphate metabolic process	GO:0006753	458	0.080
glycerolipid metabolic process	GO:0046486	108	0.077
protein folding	GO:0006457	94	0.071
regulation of protein metabolic process	GO:0051246	237	0.071
positive regulation of biosynthetic process	GO:0009891	336	0.068
proteasomal protein catabolic process	GO:0010498	141	0.067
er associated ubiquitin dependent protein catabolic process	GO:0030433	46	0.067
cellular ion homeostasis	GO:0006873	112	0.066
protein import	GO:0017038	122	0.066
organelle fission	GO:0048285	272	0.063
meiotic cell cycle	GO:0051321	272	0.063
phospholipid metabolic process	GO:0006644	125	0.062
glycerophospholipid metabolic process	GO:0006650	98	0.060
cellular chemical homeostasis	GO:0055082	123	0.060
single organism developmental process	GO:0044767	258	0.059
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.058
cell aging	GO:0007569	70	0.057
oxidation reduction process	GO:0055114	353	0.056
inner mitochondrial membrane organization	GO:0007007	26	0.054
cellular response to organic substance	GO:0071310	159	0.052
establishment of organelle localization	GO:0051656	96	0.052
lipid biosynthetic process	GO:0008610	170	0.052
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.050
phospholipid biosynthetic process	GO:0008654	89	0.049
protein transmembrane transport	GO:0071806	82	0.049
intracellular protein transmembrane transport	GO:0065002	80	0.049
negative regulation of macromolecule metabolic process	GO:0010605	375	0.048
cellular transition metal ion homeostasis	GO:0046916	59	0.047
response to external stimulus	GO:0009605	158	0.046
organonitrogen compound catabolic process	GO:1901565	404	0.045
protein localization to organelle	GO:0033365	337	0.045
positive regulation of macromolecule metabolic process	GO:0010604	394	0.044
nucleotide metabolic process	GO:0009117	453	0.042
signal transduction	GO:0007165	208	0.042
organelle fusion	GO:0048284	85	0.042
establishment of protein localization to organelle	GO:0072594	278	0.041
cellular metal ion homeostasis	GO:0006875	78	0.041
establishment of protein localization	GO:0045184	367	0.041
nucleoside metabolic process	GO:0009116	394	0.040
intracellular signal transduction	GO:0035556	112	0.039
organelle localization	GO:0051640	128	0.039
developmental process	GO:0032502	261	0.039
transition metal ion homeostasis	GO:0055076	59	0.039
mitochondrial membrane organization	GO:0007006	48	0.038
chemical homeostasis	GO:0048878	137	0.038
protein phosphorylation	GO:0006468	197	0.037
rna splicing	GO:0008380	131	0.037
cell communication	GO:0007154	345	0.037
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.037
purine ribonucleoside metabolic process	GO:0046128	380	0.037
response to organic substance	GO:0010033	182	0.036
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.036
carbohydrate derivative metabolic process	GO:1901135	549	0.035
cellular response to chemical stimulus	GO:0070887	315	0.034
purine nucleoside metabolic process	GO:0042278	380	0.033
response to temperature stimulus	GO:0009266	74	0.033
chromosome segregation	GO:0007059	159	0.033
metal ion homeostasis	GO:0055065	79	0.032
cellular amino acid metabolic process	GO:0006520	225	0.032
signaling	GO:0023052	208	0.032
organic acid metabolic process	GO:0006082	352	0.032
mitochondrial transport	GO:0006839	76	0.032
cellular amine metabolic process	GO:0044106	51	0.031
regulation of cellular protein metabolic process	GO:0032268	232	0.031
aging	GO:0007568	71	0.031
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.030
glycosyl compound metabolic process	GO:1901657	398	0.030
cellular amide metabolic process	GO:0043603	59	0.029
regulation of catabolic process	GO:0009894	199	0.029
regulation of catalytic activity	GO:0050790	307	0.029
positive regulation of protein metabolic process	GO:0051247	93	0.029
cytoskeleton organization	GO:0007010	230	0.029
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.029
cation homeostasis	GO:0055080	105	0.029
response to abiotic stimulus	GO:0009628	159	0.028
nucleobase containing small molecule metabolic process	GO:0055086	491	0.028
amine metabolic process	GO:0009308	51	0.027
mitotic cell cycle	GO:0000278	306	0.027
positive regulation of cellular catabolic process	GO:0031331	128	0.027
cellular response to external stimulus	GO:0071496	150	0.027
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.026
establishment of protein localization to mitochondrion	GO:0072655	63	0.026
intracellular protein transmembrane import	GO:0044743	67	0.026
purine ribonucleotide catabolic process	GO:0009154	327	0.026
ribonucleoside metabolic process	GO:0009119	389	0.026
purine containing compound catabolic process	GO:0072523	332	0.026
regulation of biological quality	GO:0065008	391	0.025
regulation of signal transduction	GO:0009966	114	0.025
regulation of cellular catabolic process	GO:0031329	195	0.025
protein targeting	GO:0006605	272	0.025
cellular ketone metabolic process	GO:0042180	63	0.025
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.024
positive regulation of organelle organization	GO:0010638	85	0.024
positive regulation of nucleotide metabolic process	GO:0045981	101	0.024
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.024
negative regulation of cellular metabolic process	GO:0031324	407	0.024
positive regulation of purine nucleotide metabolic process	GO:1900544	100	0.024
protein transport	GO:0015031	345	0.023
cell wall organization	GO:0071555	146	0.023
regulation of proteolysis	GO:0030162	44	0.023
positive regulation of cellular protein metabolic process	GO:0032270	89	0.023
peptide metabolic process	GO:0006518	28	0.023
nuclear division	GO:0000280	263	0.022
external encapsulating structure organization	GO:0045229	146	0.022
anion transport	GO:0006820	145	0.022
organic anion transport	GO:0015711	114	0.022
pyridine containing compound metabolic process	GO:0072524	53	0.021
response to unfolded protein	GO:0006986	29	0.021
mitotic cell cycle process	GO:1903047	294	0.021
regulation of purine nucleotide metabolic process	GO:1900542	109	0.021
single organism signaling	GO:0044700	208	0.021
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.021
glycerophospholipid biosynthetic process	GO:0046474	68	0.021
negative regulation of biosynthetic process	GO:0009890	312	0.021
nucleoside triphosphate catabolic process	GO:0009143	329	0.020
gene silencing	GO:0016458	151	0.020
regulation of cellular component biogenesis	GO:0044087	112	0.020
chromatin modification	GO:0016568	200	0.020
microtubule based process	GO:0007017	117	0.020
cellular respiration	GO:0045333	82	0.019
translation	GO:0006412	230	0.019
regulation of cell division	GO:0051302	113	0.019
conjugation with cellular fusion	GO:0000747	106	0.019
regulation of cellular ketone metabolic process	GO:0010565	42	0.019
cellular response to extracellular stimulus	GO:0031668	150	0.019
positive regulation of protein complex assembly	GO:0031334	39	0.019
ion homeostasis	GO:0050801	118	0.019
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.019
carboxylic acid metabolic process	GO:0019752	338	0.019
response to oxidative stress	GO:0006979	99	0.019
ribonucleoside catabolic process	GO:0042454	332	0.019
regulation of hydrolase activity	GO:0051336	133	0.019
ribonucleotide catabolic process	GO:0009261	327	0.019
response to nutrient levels	GO:0031667	150	0.018
nucleoside triphosphate metabolic process	GO:0009141	364	0.018
positive regulation of translation	GO:0045727	34	0.018
positive regulation of cell death	GO:0010942	3	0.018
nucleotide catabolic process	GO:0009166	330	0.018
response to topologically incorrect protein	GO:0035966	38	0.018
ribonucleotide metabolic process	GO:0009259	377	0.018
sexual reproduction	GO:0019953	216	0.018
regulation of organelle organization	GO:0033043	243	0.018
single organism membrane fusion	GO:0044801	71	0.018
mitotic cell cycle phase transition	GO:0044772	141	0.018
positive regulation of gene expression	GO:0010628	321	0.018
dna recombination	GO:0006310	172	0.018
small molecule catabolic process	GO:0044282	88	0.018
vesicle mediated transport	GO:0016192	335	0.017
positive regulation of cellular component organization	GO:0051130	116	0.017
regulation of intracellular signal transduction	GO:1902531	78	0.017
positive regulation of programmed cell death	GO:0043068	3	0.016
glycosyl compound catabolic process	GO:1901658	335	0.016
negative regulation of rna biosynthetic process	GO:1902679	260	0.016
intracellular protein transport	GO:0006886	319	0.016
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.016
response to organic cyclic compound	GO:0014070	1	0.016
regulation of anatomical structure size	GO:0090066	50	0.016
regulation of cell communication	GO:0010646	124	0.016
organic cyclic compound catabolic process	GO:1901361	499	0.016
purine nucleotide metabolic process	GO:0006163	376	0.016
nucleobase containing compound transport	GO:0015931	124	0.016
regulation of nucleotide catabolic process	GO:0030811	106	0.016
fungal type cell wall organization	GO:0031505	145	0.016
alcohol metabolic process	GO:0006066	112	0.016
regulation of nucleotide metabolic process	GO:0006140	110	0.015
negative regulation of protein metabolic process	GO:0051248	85	0.015
negative regulation of gene expression	GO:0010629	312	0.015
mitotic recombination	GO:0006312	55	0.015
membrane fusion	GO:0061025	73	0.015
response to heat	GO:0009408	69	0.015
negative regulation of signaling	GO:0023057	30	0.015
nucleoside phosphate catabolic process	GO:1901292	331	0.015
regulation of cell cycle process	GO:0010564	150	0.015
posttranscriptional regulation of gene expression	GO:0010608	115	0.014
ncrna processing	GO:0034470	330	0.014
regulation of translation	GO:0006417	89	0.014
regulation of transcription from rna polymerase ii promoter in response to stress	GO:0043618	51	0.014
chromatin silencing at rdna	GO:0000183	32	0.014
oxoacid metabolic process	GO:0043436	351	0.014
cellular response to oxidative stress	GO:0034599	94	0.014
positive regulation of molecular function	GO:0044093	185	0.014
trna metabolic process	GO:0006399	151	0.014
protein modification by small protein conjugation	GO:0032446	144	0.013
positive regulation of apoptotic process	GO:0043065	3	0.013
mitochondrial genome maintenance	GO:0000002	40	0.013
purine ribonucleotide metabolic process	GO:0009150	372	0.013
conjugation	GO:0000746	107	0.013
protein complex disassembly	GO:0043241	70	0.013
response to inorganic substance	GO:0010035	47	0.013
regulation of dna templated transcription in response to stress	GO:0043620	51	0.013
acetate biosynthetic process	GO:0019413	4	0.013
peptidyl lysine modification	GO:0018205	77	0.013
positive regulation of purine nucleotide catabolic process	GO:0033123	97	0.013
regulation of molecular function	GO:0065009	320	0.013
regulation of cell cycle	GO:0051726	195	0.013
rna splicing via transesterification reactions	GO:0000375	118	0.013
organophosphate catabolic process	GO:0046434	338	0.013
regulation of cellular component size	GO:0032535	50	0.013
protein localization to mitochondrion	GO:0070585	63	0.013
histone modification	GO:0016570	119	0.013
peptidyl amino acid modification	GO:0018193	116	0.013
cellular developmental process	GO:0048869	191	0.013
negative regulation of signal transduction	GO:0009968	30	0.012
carbohydrate derivative catabolic process	GO:1901136	339	0.012
response to pheromone involved in conjugation with cellular fusion	GO:0000749	74	0.012
regulation of nucleoside metabolic process	GO:0009118	106	0.012
actin filament organization	GO:0007015	56	0.012
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.012
regulation of gtpase activity	GO:0043087	84	0.012
meiotic nuclear division	GO:0007126	163	0.012
regulation of response to stimulus	GO:0048583	157	0.012
nucleoside catabolic process	GO:0009164	335	0.012
mitochondrion localization	GO:0051646	29	0.012
cellular protein complex assembly	GO:0043623	209	0.012
meiotic cell cycle process	GO:1903046	229	0.012
cellular response to nutrient levels	GO:0031669	144	0.012
positive regulation of catabolic process	GO:0009896	135	0.012
response to hypoxia	GO:0001666	4	0.012
nitrogen compound transport	GO:0071705	212	0.012
transmembrane transport	GO:0055085	349	0.011
regulation of mitochondrion organization	GO:0010821	20	0.011
positive regulation of cell cycle process	GO:0090068	31	0.011
ribose phosphate metabolic process	GO:0019693	384	0.011
cellular component disassembly	GO:0022411	86	0.011
protein modification by small protein conjugation or removal	GO:0070647	172	0.011
negative regulation of transcription dna templated	GO:0045892	258	0.011
autophagy	GO:0006914	106	0.011
regulation of purine nucleotide catabolic process	GO:0033121	106	0.011
chromatin silencing at silent mating type cassette	GO:0030466	53	0.011
positive regulation of mitochondrion organization	GO:0010822	16	0.011
organelle inheritance	GO:0048308	51	0.011
regulation of response to drug	GO:2001023	3	0.011
negative regulation of mapk cascade	GO:0043409	11	0.011
covalent chromatin modification	GO:0016569	119	0.011
establishment of protein localization to endoplasmic reticulum	GO:0072599	40	0.010
response to calcium ion	GO:0051592	1	0.010
chromatin silencing	GO:0006342	147	0.010
histone deacetylation	GO:0016575	26	0.010
organic acid biosynthetic process	GO:0016053	152	0.010
carboxylic acid biosynthetic process	GO:0046394	152	0.010
regulation of signaling	GO:0023051	119	0.010
carboxylic acid catabolic process	GO:0046395	71	0.010
cellular nitrogen compound catabolic process	GO:0044270	494	0.010
heterocycle catabolic process	GO:0046700	494	0.010
regulation of protein complex assembly	GO:0043254	77	0.010
response to oxygen containing compound	GO:1901700	61	0.010

MGR1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.020
	nervous system disease	DOID:863	0	0.012

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network