| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 137 | 1.000 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 203 | 1.000 | |
| ubiquitin dependent protein catabolic process | GO:0006511 | 181 | 1.000 | |
| proteolysis involved in cellular protein catabolic process | GO:0051603 | 198 | 1.000 | |
| er associated ubiquitin dependent protein catabolic process | GO:0030433 | 46 | 1.000 | |
| proteasomal protein catabolic process | GO:0010498 | 141 | 1.000 | |
| modification dependent protein catabolic process | GO:0019941 | 181 | 1.000 | |
| cellular protein catabolic process | GO:0044257 | 213 | 1.000 | |
| protein catabolic process | GO:0030163 | 221 | 0.999 | |
| proteolysis | GO:0006508 | 268 | 0.999 | |
| cellular macromolecule catabolic process | GO:0044265 | 363 | 0.998 | |
| macromolecule catabolic process | GO:0009057 | 383 | 0.964 | |
| rrna catabolic process | GO:0016075 | 31 | 0.941 | |
| ncrna catabolic process | GO:0034661 | 33 | 0.889 | |
| retrograde protein transport er to cytosol | GO:0030970 | 8 | 0.888 | |
| single organism catabolic process | GO:0044712 | 619 | 0.814 | |
| ribosome associated ubiquitin dependent protein catabolic process | GO:1990116 | 7 | 0.804 | |
| response to organic substance | GO:0010033 | 182 | 0.784 | |
| misfolded or incompletely synthesized protein catabolic process | GO:0006515 | 21 | 0.640 | |
| protein modification by small protein conjugation | GO:0032446 | 144 | 0.561 | |
| response to misfolded protein | GO:0051788 | 11 | 0.554 | |
| organelle fission | GO:0048285 | 272 | 0.549 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 172 | 0.497 | |
| intracellular protein transport | GO:0006886 | 319 | 0.493 | |
| rna catabolic process | GO:0006401 | 118 | 0.488 | |
| nucleobase containing compound catabolic process | GO:0034655 | 479 | 0.452 | |
| purine nucleotide metabolic process | GO:0006163 | 376 | 0.430 | |
| cell cycle phase transition | GO:0044770 | 144 | 0.427 | |
| cellular response to topologically incorrect protein | GO:0035967 | 32 | 0.424 | |
| protein ubiquitination | GO:0016567 | 118 | 0.418 | |
| regulation of mitotic cell cycle | GO:0007346 | 107 | 0.404 | |
| response to topologically incorrect protein | GO:0035966 | 38 | 0.397 | |
| cellular response to chemical stimulus | GO:0070887 | 315 | 0.349 | |
| positive regulation of gene expression | GO:0010628 | 321 | 0.344 | |
| single organism membrane organization | GO:0044802 | 275 | 0.343 | |
| heterocycle catabolic process | GO:0046700 | 494 | 0.314 | |
| regulation of catalytic activity | GO:0050790 | 307 | 0.288 | |
| organic cyclic compound catabolic process | GO:1901361 | 499 | 0.281 | |
| cellular response to organic substance | GO:0071310 | 159 | 0.277 | |
| cytoplasm associated proteasomal ubiquitin dependent protein catabolic process | GO:0071629 | 5 | 0.269 | |
| regulation of molecular function | GO:0065009 | 320 | 0.239 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 356 | 0.217 | |
| positive regulation of catalytic activity | GO:0043085 | 178 | 0.212 | Human Mouse |
| microtubule based process | GO:0007017 | 117 | 0.204 | |
| regulation of cellular component organization | GO:0051128 | 334 | 0.202 | |
| meiotic cell cycle | GO:0051321 | 272 | 0.198 | Worm |
| cell communication | GO:0007154 | 345 | 0.197 | |
| protein complex biogenesis | GO:0070271 | 314 | 0.196 | Human Rat |
| nucleoside triphosphate metabolic process | GO:0009141 | 364 | 0.190 | |
| chromosome segregation | GO:0007059 | 159 | 0.181 | |
| single organism signaling | GO:0044700 | 208 | 0.178 | Worm |
| response to chemical | GO:0042221 | 390 | 0.176 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 267 | 0.156 | |
| purine containing compound catabolic process | GO:0072523 | 332 | 0.155 | |
| positive regulation of biosynthetic process | GO:0009891 | 336 | 0.154 | |
| ribonucleotide catabolic process | GO:0009261 | 327 | 0.152 | |
| aromatic compound catabolic process | GO:0019439 | 491 | 0.151 | |
| protein transport | GO:0015031 | 345 | 0.149 | |
| nucleoside catabolic process | GO:0009164 | 335 | 0.146 | |
| signaling | GO:0023052 | 208 | 0.143 | Worm |
| nonfunctional rrna decay | GO:0070651 | 12 | 0.143 | |
| autophagy | GO:0006914 | 106 | 0.141 | |
| positive regulation of protein localization to nucleus | GO:1900182 | 7 | 0.137 | |
| regulation of cellular component biogenesis | GO:0044087 | 112 | 0.135 | Human |
| mitotic cell cycle | GO:0000278 | 306 | 0.132 | |
| purine ribonucleotide metabolic process | GO:0009150 | 372 | 0.130 | |
| regulation of cell cycle | GO:0051726 | 195 | 0.124 | |
| establishment of organelle localization | GO:0051656 | 96 | 0.121 | |
| microtubule cytoskeleton organization | GO:0000226 | 109 | 0.118 | |
| cytoskeleton organization | GO:0007010 | 230 | 0.115 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 494 | 0.115 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 325 | 0.109 | |
| nucleotide catabolic process | GO:0009166 | 330 | 0.109 | |
| protein complex assembly | GO:0006461 | 302 | 0.108 | Human Rat |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 286 | 0.107 | |
| organelle assembly | GO:0070925 | 118 | 0.107 | |
| nuclear division | GO:0000280 | 263 | 0.106 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 45 | 0.104 | Human |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 265 | 0.103 | |
| establishment of protein localization | GO:0045184 | 367 | 0.100 | |
| maintenance of protein location in cell | GO:0032507 | 50 | 0.098 | |
| nucleoside metabolic process | GO:0009116 | 394 | 0.095 | |
| regulation of protein localization | GO:0032880 | 62 | 0.091 | |
| membrane organization | GO:0061024 | 276 | 0.091 | |
| positive regulation of cellular component organization | GO:0051130 | 116 | 0.086 | |
| chromosome localization | GO:0050000 | 20 | 0.086 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 286 | 0.084 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 314 | 0.081 | |
| spindle organization | GO:0007051 | 37 | 0.080 | |
| mitotic nuclear division | GO:0007067 | 131 | 0.079 | |
| translation | GO:0006412 | 230 | 0.078 | |
| signal transduction | GO:0007165 | 208 | 0.078 | Worm |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 262 | 0.077 | |
| ribonucleotide metabolic process | GO:0009259 | 377 | 0.077 | |
| rrna metabolic process | GO:0016072 | 244 | 0.075 | |
| ribose phosphate metabolic process | GO:0019693 | 384 | 0.075 | |
| organelle disassembly | GO:1903008 | 13 | 0.073 | |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 327 | 0.073 | |
| purine nucleoside triphosphate metabolic process | GO:0009144 | 356 | 0.070 | |
| piecemeal microautophagy of nucleus | GO:0034727 | 33 | 0.069 | |
| regulation of cell division | GO:0051302 | 113 | 0.064 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 336 | 0.064 | |
| organophosphate catabolic process | GO:0046434 | 338 | 0.063 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 262 | 0.063 | |
| nucleoside monophosphate catabolic process | GO:0009125 | 224 | 0.062 | |
| nucleoside phosphate catabolic process | GO:1901292 | 331 | 0.062 | |
| maintenance of location | GO:0051235 | 66 | 0.060 | |
| cellular response to starvation | GO:0009267 | 90 | 0.060 | |
| maintenance of protein location | GO:0045185 | 53 | 0.059 | |
| mitotic cell cycle phase transition | GO:0044772 | 141 | 0.059 | |
| purine ribonucleoside monophosphate catabolic process | GO:0009169 | 224 | 0.059 | |
| purine ribonucleoside catabolic process | GO:0046130 | 330 | 0.058 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 394 | 0.058 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 412 | 0.056 | |
| positive regulation of protein complex assembly | GO:0031334 | 39 | 0.055 | Human |
| sister chromatid segregation | GO:0000819 | 93 | 0.055 | |
| macroautophagy | GO:0016236 | 55 | 0.055 | |
| nucleophagy | GO:0044804 | 34 | 0.054 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 68 | 0.052 | |
| ribonucleoside catabolic process | GO:0042454 | 332 | 0.051 | |
| atp catabolic process | GO:0006200 | 224 | 0.050 | |
| regulation of cellular catabolic process | GO:0031329 | 195 | 0.049 | Human Zebrafish Rat |
| sexual reproduction | GO:0019953 | 216 | 0.049 | |
| organonitrogen compound catabolic process | GO:1901565 | 404 | 0.049 | |
| cellular protein complex assembly | GO:0043623 | 209 | 0.049 | |
| purine nucleotide catabolic process | GO:0006195 | 328 | 0.048 | |
| ribonucleoside triphosphate catabolic process | GO:0009203 | 327 | 0.047 | |
| purine ribonucleoside metabolic process | GO:0046128 | 380 | 0.047 | |
| cellular response to nutrient levels | GO:0031669 | 144 | 0.047 | |
| positive regulation of hydrolase activity | GO:0051345 | 112 | 0.046 | Human Mouse |
| purine ribonucleotide catabolic process | GO:0009154 | 327 | 0.045 | |
| fungal type cell wall organization or biogenesis | GO:0071852 | 169 | 0.044 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 224 | 0.044 | |
| glutamine family amino acid metabolic process | GO:0009064 | 31 | 0.043 | |
| glycosyl compound catabolic process | GO:1901658 | 335 | 0.043 | |
| purine containing compound metabolic process | GO:0072521 | 400 | 0.041 | |
| protein localization to nucleus | GO:0034504 | 74 | 0.040 | |
| nucleoside triphosphate catabolic process | GO:0009143 | 329 | 0.040 | |
| purine nucleoside triphosphate catabolic process | GO:0009146 | 329 | 0.040 | |
| regulation of dna replication | GO:0006275 | 51 | 0.038 | |
| multi organism reproductive process | GO:0044703 | 216 | 0.037 | |
| death | GO:0016265 | 30 | 0.036 | Mouse |
| regulation of protein metabolic process | GO:0051246 | 237 | 0.035 | |
| protein localization to organelle | GO:0033365 | 337 | 0.035 | |
| atp metabolic process | GO:0046034 | 251 | 0.034 | |
| microtubule anchoring | GO:0034453 | 25 | 0.033 | |
| carbohydrate derivative catabolic process | GO:1901136 | 339 | 0.033 | |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 55 | 0.032 | |
| sister chromatid biorientation | GO:0031134 | 8 | 0.032 | |
| membrane invagination | GO:0010324 | 43 | 0.031 | |
| regulation of organelle organization | GO:0033043 | 243 | 0.031 | |
| nucleotide metabolic process | GO:0009117 | 453 | 0.031 | |
| glutamine family amino acid biosynthetic process | GO:0009084 | 18 | 0.030 | |
| nucleoside phosphate metabolic process | GO:0006753 | 458 | 0.030 | |
| positive regulation of transferase activity | GO:0051347 | 28 | 0.030 | |
| regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032434 | 30 | 0.029 | Human Rat |
| telomere organization | GO:0032200 | 75 | 0.029 | |
| regulation of cellular localization | GO:0060341 | 50 | 0.029 | |
| autophagic vacuole assembly | GO:0000045 | 16 | 0.029 | |
| cell cycle checkpoint | GO:0000075 | 82 | 0.027 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.026 | |
| peptide metabolic process | GO:0006518 | 28 | 0.025 | |
| negative regulation of proteasomal protein catabolic process | GO:1901799 | 25 | 0.025 | |
| mrna processing | GO:0006397 | 185 | 0.025 | |
| attachment of spindle microtubules to kinetochore | GO:0008608 | 25 | 0.024 | |
| negative regulation of cellular protein catabolic process | GO:1903363 | 27 | 0.024 | |
| cellular amino acid catabolic process | GO:0009063 | 48 | 0.024 | |
| negative regulation of catabolic process | GO:0009895 | 43 | 0.024 | |
| microtubule cytoskeleton organization involved in mitosis | GO:1902850 | 13 | 0.023 | |
| cellular response to dna damage stimulus | GO:0006974 | 287 | 0.023 | Human |
| oxoacid metabolic process | GO:0043436 | 351 | 0.023 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 409 | 0.022 | |
| cellular component disassembly | GO:0022411 | 86 | 0.021 | |
| positive regulation of rna metabolic process | GO:0051254 | 294 | 0.021 | |
| response to extracellular stimulus | GO:0009991 | 156 | 0.021 | |
| regulation of cellular protein metabolic process | GO:0032268 | 232 | 0.021 | |
| generation of precursor metabolites and energy | GO:0006091 | 147 | 0.021 | |
| protein complex disassembly | GO:0043241 | 70 | 0.020 | |
| regulation of protein processing | GO:0070613 | 34 | 0.020 | |
| response to organic cyclic compound | GO:0014070 | 1 | 0.020 | |
| regulation of catabolic process | GO:0009894 | 199 | 0.019 | Human Zebrafish Rat |
| single organism developmental process | GO:0044767 | 258 | 0.019 | Zebrafish Worm |
| mitochondrion organization | GO:0007005 | 261 | 0.019 | |
| cell cycle g2 m phase transition | GO:0044839 | 39 | 0.019 | |
| positive regulation of catabolic process | GO:0009896 | 135 | 0.019 | Human Rat |
| gene silencing by rna | GO:0031047 | 3 | 0.019 | |
| inclusion body assembly | GO:0070841 | 1 | 0.018 | Mouse |
| ergosterol metabolic process | GO:0008204 | 31 | 0.018 | |
| regulation of gene expression epigenetic | GO:0040029 | 147 | 0.018 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 375 | 0.018 | |
| negative regulation of cell cycle process | GO:0010948 | 86 | 0.018 | |
| regulation of cell cycle process | GO:0010564 | 150 | 0.017 | |
| purine ribonucleoside triphosphate metabolic process | GO:0009205 | 354 | 0.017 | |
| multi organism process | GO:0051704 | 233 | 0.017 | |
| developmental process | GO:0032502 | 261 | 0.016 | Zebrafish Worm |
| er nucleus signaling pathway | GO:0006984 | 23 | 0.016 | Worm |
| reproductive process | GO:0022414 | 248 | 0.016 | Worm |
| mitotic metaphase plate congression | GO:0007080 | 8 | 0.016 | |
| regulation of hydrolase activity | GO:0051336 | 133 | 0.016 | Human Mouse |
| purine nucleoside catabolic process | GO:0006152 | 330 | 0.016 | |
| macromolecular complex disassembly | GO:0032984 | 80 | 0.016 | |
| cell development | GO:0048468 | 107 | 0.015 | |
| cell wall organization | GO:0071555 | 146 | 0.015 | |
| regulation of phosphorylation | GO:0042325 | 86 | 0.015 | |
| regulation of transcription initiation from rna polymerase ii promoter | GO:0060260 | 19 | 0.015 | |
| regulation of biological quality | GO:0065008 | 391 | 0.015 | |
| response to unfolded protein | GO:0006986 | 29 | 0.015 | Worm |
| glycogen metabolic process | GO:0005977 | 30 | 0.015 | |
| regulation of protein ubiquitination | GO:0031396 | 20 | 0.015 | |
| ribonucleoside metabolic process | GO:0009119 | 389 | 0.014 | |
| cellular amide metabolic process | GO:0043603 | 59 | 0.014 | |
| positive regulation of nucleoside metabolic process | GO:0045979 | 97 | 0.014 | |
| programmed cell death | GO:0012501 | 30 | 0.014 | Mouse |
| maintenance of location in cell | GO:0051651 | 58 | 0.014 | |
| purine nucleoside metabolic process | GO:0042278 | 380 | 0.014 | |
| protein localization to endoplasmic reticulum | GO:0070972 | 47 | 0.014 | |
| positive regulation of molecular function | GO:0044093 | 185 | 0.014 | Human Mouse |
| cellular modified amino acid metabolic process | GO:0006575 | 51 | 0.014 | |
| spindle pole body organization | GO:0051300 | 33 | 0.014 | |
| aging | GO:0007568 | 71 | 0.014 | |
| purine nucleoside monophosphate catabolic process | GO:0009128 | 224 | 0.013 | |
| positive regulation of mitotic cell cycle | GO:0045931 | 16 | 0.013 | |
| regulation of cell cycle phase transition | GO:1901987 | 70 | 0.013 | |
| cellular response to extracellular stimulus | GO:0031668 | 150 | 0.013 | |
| vacuole organization | GO:0007033 | 75 | 0.013 | |
| protein deubiquitination | GO:0016579 | 17 | 0.012 | Human |
| regulation of nuclear division | GO:0051783 | 103 | 0.012 | |
| glycosyl compound metabolic process | GO:1901657 | 398 | 0.012 | |
| chromatin organization | GO:0006325 | 242 | 0.012 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.012 | |
| protein folding | GO:0006457 | 94 | 0.011 | |
| external encapsulating structure organization | GO:0045229 | 146 | 0.011 | |
| anatomical structure morphogenesis | GO:0009653 | 160 | 0.011 | |
| sporulation resulting in formation of a cellular spore | GO:0030435 | 129 | 0.011 | |
| glutathione metabolic process | GO:0006749 | 16 | 0.011 | |
| positive regulation of purine nucleotide catabolic process | GO:0033123 | 97 | 0.011 | |
| cell death | GO:0008219 | 30 | 0.010 | Mouse |
| chromatin modification | GO:0016568 | 200 | 0.010 | |
| metaphase plate congression | GO:0051310 | 8 | 0.010 | |
| chromatin assembly or disassembly | GO:0006333 | 60 | 0.010 | |
| double strand break repair via homologous recombination | GO:0000724 | 54 | 0.010 | |
| negative regulation of gene expression | GO:0010629 | 312 | 0.010 | |
| anatomical structure homeostasis | GO:0060249 | 74 | 0.010 | |
| negative regulation of proteasomal ubiquitin dependent protein catabolic process | GO:0032435 | 24 | 0.010 | |
| regulation of chromosome organization | GO:0033044 | 66 | 0.010 | |
