IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

160 known processes

GCS1 (YDL226C)

Gcs1p

SGD: S000002385
Entrez: 851372
UniProtKB: P35197

Process Predictions
Disease Predictions

GCS1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
single organism membrane organization	GO:0044802	275	0.876
membrane organization	GO:0061024	276	0.760
developmental process	GO:0032502	261	0.706
single organism developmental process	GO:0044767	258	0.704
cell differentiation	GO:0030154	161	0.673
establishment of protein localization to membrane	GO:0090150	99	0.628
protein transport	GO:0015031	345	0.624
negative regulation of cellular metabolic process	GO:0031324	407	0.575
intracellular protein transport	GO:0006886	319	0.532
golgi vesicle transport	GO:0048193	188	0.519
meiotic cell cycle process	GO:1903046	229	0.494
vesicle mediated transport	GO:0016192	335	0.466
single organism reproductive process	GO:0044702	159	0.439
lipid transport	GO:0006869	58	0.434
cellular developmental process	GO:0048869	191	0.427
establishment of protein localization	GO:0045184	367	0.427
single organism cellular localization	GO:1902580	375	0.401
cellular lipid metabolic process	GO:0044255	229	0.397
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.387
post golgi vesicle mediated transport	GO:0006892	72	0.370
regulation of phosphate metabolic process	GO:0019220	230	0.330
single organism catabolic process	GO:0044712	619	0.328
negative regulation of biosynthetic process	GO:0009890	312	0.309
phosphatidylinositol metabolic process	GO:0046488	62	0.295
organic acid biosynthetic process	GO:0016053	152	0.295
carboxylic acid biosynthetic process	GO:0046394	152	0.288
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.282
anatomical structure morphogenesis	GO:0009653	160	0.242
anatomical structure development	GO:0048856	160	0.234
phospholipid metabolic process	GO:0006644	125	0.224
regulation of lipid metabolic process	GO:0019216	45	0.222
regulation of vesicle mediated transport	GO:0060627	39	0.222
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.218
secretion by cell	GO:0032940	50	0.216
negative regulation of gene expression	GO:0010629	312	0.215
small molecule biosynthetic process	GO:0044283	258	0.215
response to chemical	GO:0042221	390	0.205
carbohydrate derivative metabolic process	GO:1901135	549	0.203
signaling	GO:0023052	208	0.191
sporulation	GO:0043934	132	0.188
developmental process involved in reproduction	GO:0003006	159	0.187
negative regulation of macromolecule metabolic process	GO:0010605	375	0.185
organelle fission	GO:0048285	272	0.180
lipid biosynthetic process	GO:0008610	170	0.179
regulation of catalytic activity	GO:0050790	307	0.176
mitotic cell cycle process	GO:1903047	294	0.175
regulation of molecular function	GO:0065009	320	0.170
meiotic cell cycle	GO:0051321	272	0.164
chromatin silencing	GO:0006342	147	0.152
lipid metabolic process	GO:0006629	269	0.152
regulation of cellular component organization	GO:0051128	334	0.149
mitotic cell cycle	GO:0000278	306	0.148
regulation of transport	GO:0051049	85	0.147
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.147
regulation of phosphorus metabolic process	GO:0051174	230	0.147
negative regulation of cellular biosynthetic process	GO:0031327	312	0.146
protein complex assembly	GO:0006461	302	0.146
regulation of gene expression epigenetic	GO:0040029	147	0.145
regulation of biological quality	GO:0065008	391	0.144
sexual sporulation	GO:0034293	113	0.142
cellular protein complex assembly	GO:0043623	209	0.140
positive regulation of biosynthetic process	GO:0009891	336	0.139
sexual reproduction	GO:0019953	216	0.139
protein localization to membrane	GO:0072657	102	0.134
gene silencing	GO:0016458	151	0.133
reproductive process	GO:0022414	248	0.133
phospholipid transport	GO:0015914	23	0.127
cellular amino acid metabolic process	GO:0006520	225	0.125
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.124
membrane fusion	GO:0061025	73	0.122
glycerophospholipid metabolic process	GO:0006650	98	0.120
positive regulation of cellular biosynthetic process	GO:0031328	336	0.119
secretion	GO:0046903	50	0.118
homeostatic process	GO:0042592	227	0.114
macromolecule catabolic process	GO:0009057	383	0.112
organic acid metabolic process	GO:0006082	352	0.111
cellular response to dna damage stimulus	GO:0006974	287	0.110
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.110
negative regulation of rna biosynthetic process	GO:1902679	260	0.107
signal transduction	GO:0007165	208	0.104
cell communication	GO:0007154	345	0.103
positive regulation of phosphorus metabolic process	GO:0010562	147	0.102
cytoskeleton organization	GO:0007010	230	0.099
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.097
lipid localization	GO:0010876	60	0.097
negative regulation of rna metabolic process	GO:0051253	262	0.095
cellular macromolecule catabolic process	GO:0044265	363	0.095
positive regulation of transcription dna templated	GO:0045893	286	0.093
endosomal transport	GO:0016197	86	0.092
vesicle organization	GO:0016050	68	0.092
nucleotide metabolic process	GO:0009117	453	0.092
negative regulation of transcription dna templated	GO:0045892	258	0.091
carboxylic acid metabolic process	GO:0019752	338	0.091
organonitrogen compound biosynthetic process	GO:1901566	314	0.090
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.088
glycerophospholipid biosynthetic process	GO:0046474	68	0.087
sphingolipid biosynthetic process	GO:0030148	29	0.085
reproduction of a single celled organism	GO:0032505	191	0.083
negative regulation of gene expression epigenetic	GO:0045814	147	0.083
response to organic substance	GO:0010033	182	0.083
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.082
establishment or maintenance of cell polarity	GO:0007163	96	0.082
regulation of localization	GO:0032879	127	0.075
dephosphorylation	GO:0016311	127	0.074
positive regulation of gene expression	GO:0010628	321	0.073
positive regulation of phosphate metabolic process	GO:0045937	147	0.070
cellular ion homeostasis	GO:0006873	112	0.070
vacuole organization	GO:0007033	75	0.070
proteolysis	GO:0006508	268	0.070
cellular nitrogen compound catabolic process	GO:0044270	494	0.068
establishment of protein localization to organelle	GO:0072594	278	0.067
mitotic cytokinesis	GO:0000281	58	0.066
monocarboxylic acid metabolic process	GO:0032787	122	0.066
protein processing	GO:0016485	64	0.066
purine ribonucleoside catabolic process	GO:0046130	330	0.065
single organism signaling	GO:0044700	208	0.065
endomembrane system organization	GO:0010256	74	0.064
meiotic nuclear division	GO:0007126	163	0.064
cellular chemical homeostasis	GO:0055082	123	0.063
cytokinesis	GO:0000910	92	0.063
reproductive process in single celled organism	GO:0022413	145	0.063
ribonucleoside catabolic process	GO:0042454	332	0.063
regulation of cellular localization	GO:0060341	50	0.062
multi organism reproductive process	GO:0044703	216	0.061
regulation of response to stimulus	GO:0048583	157	0.061
nucleoside catabolic process	GO:0009164	335	0.060
cellular cation homeostasis	GO:0030003	100	0.060
plasma membrane organization	GO:0007009	21	0.059
glycosyl compound catabolic process	GO:1901658	335	0.058
multi organism process	GO:0051704	233	0.058
alpha amino acid biosynthetic process	GO:1901607	91	0.056
nuclear division	GO:0000280	263	0.055
regulation of nuclear division	GO:0051783	103	0.055
cellular homeostasis	GO:0019725	138	0.054
exocytosis	GO:0006887	42	0.054
regulation of cellular catabolic process	GO:0031329	195	0.053
positive regulation of rna metabolic process	GO:0051254	294	0.052
protein complex biogenesis	GO:0070271	314	0.052
ion transport	GO:0006811	274	0.051
oxoacid metabolic process	GO:0043436	351	0.050
cellular response to oxygen containing compound	GO:1901701	43	0.049
cellular response to chemical stimulus	GO:0070887	315	0.048
aromatic compound catabolic process	GO:0019439	491	0.048
glycerolipid metabolic process	GO:0046486	108	0.048
golgi to plasma membrane transport	GO:0006893	33	0.047
cell surface receptor signaling pathway	GO:0007166	38	0.046
nucleobase containing small molecule metabolic process	GO:0055086	491	0.044
purine ribonucleotide metabolic process	GO:0009150	372	0.044
positive regulation of molecular function	GO:0044093	185	0.044
regulation of lipid biosynthetic process	GO:0046890	32	0.044
cellular amino acid biosynthetic process	GO:0008652	118	0.043
single organism carbohydrate metabolic process	GO:0044723	237	0.043
protein maturation	GO:0051604	76	0.042
regulation of carbohydrate metabolic process	GO:0006109	43	0.042
positive regulation of catalytic activity	GO:0043085	178	0.042
heterocycle catabolic process	GO:0046700	494	0.041
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.040
regulation of signaling	GO:0023051	119	0.040
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.040
ribonucleoprotein complex subunit organization	GO:0071826	152	0.040
cellular component morphogenesis	GO:0032989	97	0.039
glycerolipid biosynthetic process	GO:0045017	71	0.038
chemical homeostasis	GO:0048878	137	0.038
dna repair	GO:0006281	236	0.038
organophosphate biosynthetic process	GO:0090407	182	0.038
regulation of nucleoside metabolic process	GO:0009118	106	0.038
purine nucleoside metabolic process	GO:0042278	380	0.038
organophosphate ester transport	GO:0015748	45	0.037
microtubule based process	GO:0007017	117	0.036
cellular response to external stimulus	GO:0071496	150	0.036
vacuolar transport	GO:0007034	145	0.036
carbohydrate biosynthetic process	GO:0016051	82	0.036
organophosphate metabolic process	GO:0019637	597	0.035
organonitrogen compound catabolic process	GO:1901565	404	0.035
organelle assembly	GO:0070925	118	0.035
cellular component assembly involved in morphogenesis	GO:0010927	73	0.035
nucleobase containing compound catabolic process	GO:0034655	479	0.034
negative regulation of organelle organization	GO:0010639	103	0.034
modification dependent protein catabolic process	GO:0019941	181	0.034
protein catabolic process	GO:0030163	221	0.034
negative regulation of cellular component organization	GO:0051129	109	0.034
ascospore formation	GO:0030437	107	0.034
regulation of cell communication	GO:0010646	124	0.034
cellular response to organic substance	GO:0071310	159	0.033
cellular response to extracellular stimulus	GO:0031668	150	0.033
mitotic nuclear division	GO:0007067	131	0.033
regulation of cell division	GO:0051302	113	0.033
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.032
establishment of organelle localization	GO:0051656	96	0.032
cation homeostasis	GO:0055080	105	0.032
cell division	GO:0051301	205	0.032
response to oxygen containing compound	GO:1901700	61	0.031
establishment of protein localization to plasma membrane	GO:0090002	17	0.031
membrane docking	GO:0022406	22	0.031
ion homeostasis	GO:0050801	118	0.030
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.030
carbohydrate metabolic process	GO:0005975	252	0.030
regulation of meiosis	GO:0040020	42	0.030
macromolecule methylation	GO:0043414	85	0.030
protein localization to plasma membrane	GO:0072659	18	0.030
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.030
positive regulation of exocytosis	GO:0045921	2	0.029
nucleoside triphosphate catabolic process	GO:0009143	329	0.028
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.028
ribose phosphate metabolic process	GO:0019693	384	0.028
endoplasmic reticulum organization	GO:0007029	30	0.028
translation	GO:0006412	230	0.028
cellular amine metabolic process	GO:0044106	51	0.028
organic hydroxy compound metabolic process	GO:1901615	125	0.028
negative regulation of nuclear division	GO:0051784	62	0.027
carbohydrate derivative catabolic process	GO:1901136	339	0.027
purine containing compound catabolic process	GO:0072523	332	0.027
positive regulation of rna biosynthetic process	GO:1902680	286	0.027
negative regulation of phosphorus metabolic process	GO:0010563	49	0.027
positive regulation of macromolecule metabolic process	GO:0010604	394	0.027
alpha amino acid metabolic process	GO:1901605	124	0.027
nucleoside phosphate metabolic process	GO:0006753	458	0.026
regulation of dna templated transcription elongation	GO:0032784	44	0.026
response to nutrient levels	GO:0031667	150	0.026
organic cyclic compound catabolic process	GO:1901361	499	0.026
covalent chromatin modification	GO:0016569	119	0.026
cellular carbohydrate biosynthetic process	GO:0034637	49	0.026
regulation of purine nucleotide metabolic process	GO:1900542	109	0.025
purine nucleoside catabolic process	GO:0006152	330	0.025
positive regulation of cellular component organization	GO:0051130	116	0.025
negative regulation of phosphate metabolic process	GO:0045936	49	0.025
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.025
mitotic cytokinetic process	GO:1902410	45	0.024
er to golgi vesicle mediated transport	GO:0006888	86	0.024
microtubule cytoskeleton organization	GO:0000226	109	0.024
glycoprotein metabolic process	GO:0009100	62	0.023
regulation of meiotic cell cycle	GO:0051445	43	0.023
regulation of catabolic process	GO:0009894	199	0.023
cellular response to nutrient levels	GO:0031669	144	0.023
amine metabolic process	GO:0009308	51	0.023
regulation of dephosphorylation	GO:0035303	18	0.022
cellular component disassembly	GO:0022411	86	0.022
endocytosis	GO:0006897	90	0.022
nucleoside phosphate catabolic process	GO:1901292	331	0.022
iron ion homeostasis	GO:0055072	34	0.021
protein localization to nucleus	GO:0034504	74	0.021
regulation of cellular protein metabolic process	GO:0032268	232	0.021
regulation of signal transduction	GO:0009966	114	0.021
cellular biogenic amine metabolic process	GO:0006576	37	0.021
positive regulation of nucleoside metabolic process	GO:0045979	97	0.021
establishment of cell polarity	GO:0030010	64	0.021
spindle organization	GO:0007051	37	0.020
cellular ketone metabolic process	GO:0042180	63	0.020
regulation of protein localization	GO:0032880	62	0.019
cellular modified amino acid metabolic process	GO:0006575	51	0.019
organelle localization	GO:0051640	128	0.019
purine ribonucleotide catabolic process	GO:0009154	327	0.019
response to external stimulus	GO:0009605	158	0.019
cell development	GO:0048468	107	0.018
regulation of nucleotide metabolic process	GO:0006140	110	0.018
protein complex disassembly	GO:0043241	70	0.018
generation of precursor metabolites and energy	GO:0006091	147	0.018
positive regulation of dna templated transcription elongation	GO:0032786	42	0.018
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.018
nucleoside triphosphate metabolic process	GO:0009141	364	0.018
steroid metabolic process	GO:0008202	47	0.018
response to organic cyclic compound	GO:0014070	1	0.018
regulation of organelle organization	GO:0033043	243	0.017
purine nucleotide catabolic process	GO:0006195	328	0.017
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.017
protein acylation	GO:0043543	66	0.017
chromatin remodeling	GO:0006338	80	0.017
modification dependent macromolecule catabolic process	GO:0043632	203	0.017
regulation of cellular component biogenesis	GO:0044087	112	0.016
ribosomal small subunit biogenesis	GO:0042274	124	0.016
gtp metabolic process	GO:0046039	107	0.016
cytoskeleton dependent cytokinesis	GO:0061640	65	0.016
cell death	GO:0008219	30	0.016
single organism membrane fusion	GO:0044801	71	0.016
chromatin modification	GO:0016568	200	0.015
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.015
positive regulation of hydrolase activity	GO:0051345	112	0.015
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.015
programmed cell death	GO:0012501	30	0.015
organelle fusion	GO:0048284	85	0.015
positive regulation of cellular catabolic process	GO:0031331	128	0.015
regulation of phospholipid biosynthetic process	GO:0071071	15	0.014
glycoprotein biosynthetic process	GO:0009101	61	0.014
vesicle fusion	GO:0006906	33	0.014
filamentous growth	GO:0030447	124	0.014
organophosphate catabolic process	GO:0046434	338	0.014
alcohol metabolic process	GO:0006066	112	0.014
regulation of cellular ketone metabolic process	GO:0010565	42	0.014
guanosine containing compound catabolic process	GO:1901069	109	0.014
response to hexose	GO:0009746	13	0.014
aging	GO:0007568	71	0.014
sterol biosynthetic process	GO:0016126	35	0.013
response to extracellular stimulus	GO:0009991	156	0.013
ribonucleotide catabolic process	GO:0009261	327	0.013
response to monosaccharide	GO:0034284	13	0.013
response to nutrient	GO:0007584	52	0.013
positive regulation of purine nucleotide metabolic process	GO:1900544	100	0.013
amide transport	GO:0042886	22	0.013
response to abiotic stimulus	GO:0009628	159	0.013
nucleotide catabolic process	GO:0009166	330	0.013
peptide transport	GO:0015833	14	0.013
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.013
positive regulation of gtp catabolic process	GO:0033126	80	0.013
phospholipid biosynthetic process	GO:0008654	89	0.013
regulation of nucleotide catabolic process	GO:0030811	106	0.012
sterol metabolic process	GO:0016125	47	0.012
ribonucleotide metabolic process	GO:0009259	377	0.012
positive regulation of secretion	GO:0051047	2	0.012
glycosylation	GO:0070085	66	0.012
dna templated transcription elongation	GO:0006354	91	0.012
purine containing compound metabolic process	GO:0072521	400	0.012
regulation of kinase activity	GO:0043549	71	0.012
macromolecule glycosylation	GO:0043413	57	0.012
positive regulation of nucleotide catabolic process	GO:0030813	97	0.011
polysaccharide metabolic process	GO:0005976	60	0.011
ubiquitin dependent protein catabolic process	GO:0006511	181	0.011
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.011
cellular response to oxidative stress	GO:0034599	94	0.011
actin cytoskeleton organization	GO:0030036	100	0.011
cytokinetic process	GO:0032506	78	0.011
methylation	GO:0032259	101	0.011
positive regulation of purine nucleotide catabolic process	GO:0033123	97	0.011
atp catabolic process	GO:0006200	224	0.010
trna metabolic process	GO:0006399	151	0.010
fatty acid biosynthetic process	GO:0006633	22	0.010
regulation of protein metabolic process	GO:0051246	237	0.010
actin filament based process	GO:0030029	104	0.010
polysaccharide biosynthetic process	GO:0000271	39	0.010

GCS1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.023

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network