IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

186 known processes

BMH2 (YDR099W)

Bmh2p

(Aliases: SCD3)

Entrez: 851676
SGD: S000002506
UniProtKB: P34730

Process Predictions
Disease Predictions

BMH2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
protein phosphorylation	GO:0006468	197	0.976	Mouse
mitotic cell cycle process	GO:1903047	294	0.933
single organism catabolic process	GO:0044712	619	0.915
cell wall biogenesis	GO:0042546	93	0.889
signaling	GO:0023052	208	0.841
regulation of localization	GO:0032879	127	0.833	Human Mouse
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.824	Yeast
negative regulation of gene expression	GO:0010629	312	0.818	Human Yeast
regulation of cellular component organization	GO:0051128	334	0.817	Yeast Mouse
cytoskeleton organization	GO:0007010	230	0.809	Fly
signal transduction	GO:0007165	208	0.808
reproductive process	GO:0022414	248	0.799
single organism signaling	GO:0044700	208	0.797
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.774
developmental process involved in reproduction	GO:0003006	159	0.771
mitotic cell cycle	GO:0000278	306	0.764
cell cycle phase transition	GO:0044770	144	0.750	Yeast
growth	GO:0040007	157	0.706
carbohydrate derivative biosynthetic process	GO:1901137	181	0.697
ascospore formation	GO:0030437	107	0.694
multi organism process	GO:0051704	233	0.690
endocytosis	GO:0006897	90	0.689
meiotic cell cycle process	GO:1903046	229	0.675
sexual reproduction	GO:0019953	216	0.645
intracellular signal transduction	GO:0035556	112	0.601
phosphorylation	GO:0016310	291	0.596	Mouse Fly
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.582	Human Yeast
cell development	GO:0048468	107	0.572
cellular response to dna damage stimulus	GO:0006974	287	0.565
cell communication	GO:0007154	345	0.563
response to external stimulus	GO:0009605	158	0.556
fungal type cell wall biogenesis	GO:0009272	80	0.553
protein catabolic process	GO:0030163	221	0.530
regulation of cell communication	GO:0010646	124	0.518	Human Fly
multi organism reproductive process	GO:0044703	216	0.490
negative regulation of cellular metabolic process	GO:0031324	407	0.488
cellular lipid metabolic process	GO:0044255	229	0.482
cellular component disassembly	GO:0022411	86	0.480
proteolysis	GO:0006508	268	0.457	Human
glycogen metabolic process	GO:0005977	30	0.457
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.455	Human Yeast
negative regulation of biosynthetic process	GO:0009890	312	0.453	Human Yeast
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.429
regulation of protein metabolic process	GO:0051246	237	0.427
regulation of transport	GO:0051049	85	0.411	Human Mouse
single organism developmental process	GO:0044767	258	0.406
spindle checkpoint	GO:0031577	35	0.402	Yeast
cell division	GO:0051301	205	0.393	Yeast Mouse
cellular protein catabolic process	GO:0044257	213	0.385
cellular macromolecule catabolic process	GO:0044265	363	0.367
cellular carbohydrate metabolic process	GO:0044262	135	0.357
negative regulation of rna metabolic process	GO:0051253	262	0.356	Human Yeast
reproduction of a single celled organism	GO:0032505	191	0.353
cell differentiation	GO:0030154	161	0.338
dephosphorylation	GO:0016311	127	0.331	Human Mouse
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.318	Yeast
carbohydrate derivative metabolic process	GO:1901135	549	0.274
sexual sporulation	GO:0034293	113	0.270
mitotic cell cycle checkpoint	GO:0007093	56	0.269	Yeast
regulation of cellular catabolic process	GO:0031329	195	0.268
lipid metabolic process	GO:0006629	269	0.262
cellular glucan metabolic process	GO:0006073	44	0.257
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.247	Human Yeast
developmental process	GO:0032502	261	0.244
single organism carbohydrate metabolic process	GO:0044723	237	0.220
cell wall organization or biogenesis	GO:0071554	190	0.217
regulation of biological quality	GO:0065008	391	0.212	Human Mouse Fly
sporulation	GO:0043934	132	0.200
organophosphate metabolic process	GO:0019637	597	0.199
negative regulation of cellular component organization	GO:0051129	109	0.198	Yeast
sister chromatid segregation	GO:0000819	93	0.192
negative regulation of macromolecule metabolic process	GO:0010605	375	0.186
regulation of cell cycle	GO:0051726	195	0.184	Yeast Mouse
regulation of vesicle mediated transport	GO:0060627	39	0.176
response to extracellular stimulus	GO:0009991	156	0.175
glucosamine containing compound biosynthetic process	GO:1901073	15	0.175
mitotic nuclear division	GO:0007067	131	0.168	Yeast
cellular response to external stimulus	GO:0071496	150	0.163
regulation of molecular function	GO:0065009	320	0.162
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.160
glucan metabolic process	GO:0044042	44	0.158
regulation of organelle organization	GO:0033043	243	0.158	Yeast
vesicle mediated transport	GO:0016192	335	0.158
negative regulation of transcription dna templated	GO:0045892	258	0.156	Human Yeast
secretion	GO:0046903	50	0.155
positive regulation of transport	GO:0051050	32	0.155	Mouse
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.154
reproductive process in single celled organism	GO:0022413	145	0.152
regulation of protein modification process	GO:0031399	110	0.148
actin cytoskeleton organization	GO:0030036	100	0.147
negative regulation of cellular biosynthetic process	GO:0031327	312	0.145	Human Yeast
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.144	Human Yeast
anatomical structure development	GO:0048856	160	0.144
microtubule based process	GO:0007017	117	0.143	Fly
filamentous growth	GO:0030447	124	0.141
establishment or maintenance of cell polarity	GO:0007163	96	0.135	Fly
negative regulation of molecular function	GO:0044092	68	0.125
cellular protein complex disassembly	GO:0043624	42	0.124
secretion by cell	GO:0032940	50	0.122
regulation of phosphate metabolic process	GO:0019220	230	0.118	Human Mouse Fly
mitotic spindle checkpoint	GO:0071174	34	0.118	Yeast
lipid biosynthetic process	GO:0008610	170	0.117
carbohydrate metabolic process	GO:0005975	252	0.116
negative regulation of protein depolymerization	GO:1901880	12	0.115
regulation of catabolic process	GO:0009894	199	0.113
negative regulation of cytoskeleton organization	GO:0051494	24	0.112
regulation of protein localization	GO:0032880	62	0.111	Human Mouse
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	36	0.106
proteasomal protein catabolic process	GO:0010498	141	0.105
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.100
response to pheromone	GO:0019236	92	0.098
polysaccharide biosynthetic process	GO:0000271	39	0.097
regulation of growth	GO:0040008	50	0.096	Mouse
regulation of anatomical structure size	GO:0090066	50	0.095
negative regulation of cell cycle phase transition	GO:1901988	59	0.094	Yeast
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.093
carbohydrate biosynthetic process	GO:0016051	82	0.091
cell wall assembly	GO:0070726	54	0.090
oxidation reduction process	GO:0055114	353	0.090
positive regulation of cellular component organization	GO:0051130	116	0.089
filamentous growth of a population of unicellular organisms	GO:0044182	109	0.088
negative regulation of cell division	GO:0051782	66	0.088	Yeast
positive regulation of cell communication	GO:0010647	28	0.087	Fly
energy reserve metabolic process	GO:0006112	32	0.087
regulation of cellular protein metabolic process	GO:0032268	232	0.086
cellular developmental process	GO:0048869	191	0.085
response to nutrient levels	GO:0031667	150	0.084
organelle fission	GO:0048285	272	0.083	Yeast
spindle organization	GO:0007051	37	0.082
regulation of cell cycle process	GO:0010564	150	0.081	Yeast
positive regulation of macromolecule metabolic process	GO:0010604	394	0.080
mitochondrion organization	GO:0007005	261	0.080	Human
conjugation with cellular fusion	GO:0000747	106	0.079
regulation of response to stress	GO:0080134	57	0.076
macromolecular complex disassembly	GO:0032984	80	0.075
mitotic sister chromatid segregation	GO:0000070	85	0.074
protein complex disassembly	GO:0043241	70	0.070
nuclear export	GO:0051168	124	0.066	Mouse
cell cycle checkpoint	GO:0000075	82	0.066
purine nucleotide metabolic process	GO:0006163	376	0.066
regulation of phosphorus metabolic process	GO:0051174	230	0.066	Human Mouse Fly
positive regulation of signaling	GO:0023056	20	0.064	Fly
negative regulation of organelle organization	GO:0010639	103	0.064	Yeast
anatomical structure morphogenesis	GO:0009653	160	0.064
negative regulation of nuclear division	GO:0051784	62	0.064	Yeast
response to heat	GO:0009408	69	0.063
cell growth	GO:0016049	89	0.063
cellular polysaccharide metabolic process	GO:0044264	55	0.061
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.061	Yeast
mitotic spindle organization	GO:0007052	30	0.059
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.059	Human Yeast
negative regulation of proteolysis	GO:0045861	33	0.057	Human
regulation of catalytic activity	GO:0050790	307	0.056
energy derivation by oxidation of organic compounds	GO:0015980	125	0.055
establishment of organelle localization	GO:0051656	96	0.055
regulation of filamentous growth	GO:0010570	38	0.054
organonitrogen compound biosynthetic process	GO:1901566	314	0.054
protein depolymerization	GO:0051261	21	0.054
protein complex assembly	GO:0006461	302	0.054
regulation of dephosphorylation	GO:0035303	18	0.053	Human Mouse
mitotic cell cycle phase transition	GO:0044772	141	0.053	Yeast
replicative cell aging	GO:0001302	46	0.053
regulation of dna replication	GO:0006275	51	0.053
response to chemical	GO:0042221	390	0.052
ras protein signal transduction	GO:0007265	29	0.052
cellular polysaccharide biosynthetic process	GO:0033692	38	0.051
negative regulation of mitotic cell cycle	GO:0045930	63	0.051	Yeast
polysaccharide metabolic process	GO:0005976	60	0.050
regulation of signal transduction	GO:0009966	114	0.050	Fly
positive regulation of rna metabolic process	GO:0051254	294	0.049
cell wall chitin biosynthetic process	GO:0006038	12	0.048
establishment of protein localization	GO:0045184	367	0.046	Human Mouse
regulation of cellular response to stress	GO:0080135	50	0.046
chromosome segregation	GO:0007059	159	0.045	Fly
macromolecule catabolic process	GO:0009057	383	0.045
positive regulation of rna biosynthetic process	GO:1902680	286	0.045
protein modification by small protein conjugation or removal	GO:0070647	172	0.045
conjugation	GO:0000746	107	0.045
regulation of lipid metabolic process	GO:0019216	45	0.044
negative regulation of rna biosynthetic process	GO:1902679	260	0.044	Human Yeast
regulation of protein complex assembly	GO:0043254	77	0.042
protein dephosphorylation	GO:0006470	40	0.042	Human Mouse
regulation of lipid biosynthetic process	GO:0046890	32	0.042
regulation of protein dephosphorylation	GO:0035304	4	0.042	Human Mouse
dna replication	GO:0006260	147	0.042
regulation of nuclear division	GO:0051783	103	0.040	Yeast
meiotic cell cycle	GO:0051321	272	0.039
response to starvation	GO:0042594	96	0.039
maintenance of protein location	GO:0045185	53	0.039	Human
iron sulfur cluster assembly	GO:0016226	22	0.039
regulation of response to stimulus	GO:0048583	157	0.039	Fly
regulation of protein processing	GO:0070613	34	0.038	Human
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	137	0.036
homeostatic process	GO:0042592	227	0.036	Mouse
negative regulation of catabolic process	GO:0009895	43	0.036
cellular response to nutrient levels	GO:0031669	144	0.035
positive regulation of gene expression	GO:0010628	321	0.035
maintenance of location	GO:0051235	66	0.035	Human
regulation of proteolysis	GO:0030162	44	0.035	Human
cytoskeleton dependent cytokinesis	GO:0061640	65	0.035
positive regulation of intracellular protein transport	GO:0090316	3	0.035	Mouse
glycoprotein metabolic process	GO:0009100	62	0.035
glycerophospholipid metabolic process	GO:0006650	98	0.034
positive regulation of catalytic activity	GO:0043085	178	0.034	Human
single organism nuclear import	GO:1902593	56	0.033
aging	GO:0007568	71	0.033
regulation of cytoskeleton organization	GO:0051493	63	0.032
maintenance of location in cell	GO:0051651	58	0.032	Human
maintenance of protein location in cell	GO:0032507	50	0.032	Human
positive regulation of molecular function	GO:0044093	185	0.032	Human
response to oxygen containing compound	GO:1901700	61	0.031
regulation of cellular localization	GO:0060341	50	0.031	Mouse
ribonucleotide metabolic process	GO:0009259	377	0.031
actin filament organization	GO:0007015	56	0.031
nucleoside phosphate catabolic process	GO:1901292	331	0.030
protein folding	GO:0006457	94	0.030	Fly
cellular response to organic substance	GO:0071310	159	0.030
negative regulation of cell cycle	GO:0045786	91	0.030	Yeast
negative regulation of cell cycle process	GO:0010948	86	0.029	Yeast
regulation of signaling	GO:0023051	119	0.028	Human Fly
glycerolipid metabolic process	GO:0046486	108	0.028
cell death	GO:0008219	30	0.028
dna replication initiation	GO:0006270	48	0.027
negative regulation of phosphate metabolic process	GO:0045936	49	0.027	Human Mouse
protein export from nucleus	GO:0006611	17	0.027	Mouse
phospholipid metabolic process	GO:0006644	125	0.027
programmed cell death	GO:0012501	30	0.027
regulation of hydrolase activity	GO:0051336	133	0.027	Human
metallo sulfur cluster assembly	GO:0031163	22	0.026
positive regulation of response to stimulus	GO:0048584	37	0.026	Fly
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.026
autophagy	GO:0006914	106	0.026
organonitrogen compound catabolic process	GO:1901565	404	0.025
purine ribonucleoside metabolic process	GO:0046128	380	0.025
fungal type cell wall organization or biogenesis	GO:0071852	169	0.025
positive regulation of organelle organization	GO:0010638	85	0.024
aminoglycan biosynthetic process	GO:0006023	15	0.024
negative regulation of protein maturation	GO:1903318	33	0.024	Human
death	GO:0016265	30	0.024
posttranscriptional regulation of gene expression	GO:0010608	115	0.024	Fly
nucleocytoplasmic transport	GO:0006913	163	0.024	Mouse
cell aging	GO:0007569	70	0.023
generation of precursor metabolites and energy	GO:0006091	147	0.023
protein autophosphorylation	GO:0046777	15	0.023
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.023
negative regulation of protein modification process	GO:0031400	37	0.023
cell wall macromolecule biosynthetic process	GO:0044038	24	0.023
positive regulation of cell growth	GO:0030307	7	0.023	Mouse
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.023
dna dependent dna replication	GO:0006261	115	0.023
nuclear division	GO:0000280	263	0.023	Yeast
regulation of microtubule cytoskeleton organization	GO:0070507	32	0.022
positive regulation of cellular catabolic process	GO:0031331	128	0.022
regulation of cellular protein catabolic process	GO:1903362	36	0.022
protein complex biogenesis	GO:0070271	314	0.022
positive regulation of biosynthetic process	GO:0009891	336	0.022
positive regulation of signal transduction	GO:0009967	20	0.022	Fly
positive regulation of nucleocytoplasmic transport	GO:0046824	4	0.021	Mouse
chromatin organization	GO:0006325	242	0.021
cellular component assembly involved in morphogenesis	GO:0010927	73	0.021
positive regulation of cellular biosynthetic process	GO:0031328	336	0.021
nitrogen compound transport	GO:0071705	212	0.021
cellular component movement	GO:0006928	20	0.020	Mouse
purine containing compound metabolic process	GO:0072521	400	0.020
negative regulation of protein complex disassembly	GO:0043242	14	0.020
nucleoside metabolic process	GO:0009116	394	0.020
regulation of dna metabolic process	GO:0051052	100	0.020
regulation of protein maturation	GO:1903317	34	0.020	Human
multi organism cellular process	GO:0044764	120	0.020
positive regulation of catabolic process	GO:0009896	135	0.020
microtubule cytoskeleton organization involved in mitosis	GO:1902850	13	0.020
ion homeostasis	GO:0050801	118	0.020
pseudohyphal growth	GO:0007124	75	0.020
regulation of kinase activity	GO:0043549	71	0.019	Mouse
cellular response to chemical stimulus	GO:0070887	315	0.019
protein modification by small protein conjugation	GO:0032446	144	0.018
sterol metabolic process	GO:0016125	47	0.018
protein processing	GO:0016485	64	0.018	Human
negative regulation of cellular catabolic process	GO:0031330	43	0.018
nucleotide biosynthetic process	GO:0009165	79	0.017
response to organic cyclic compound	GO:0014070	1	0.017
steroid biosynthetic process	GO:0006694	35	0.017
protein transport	GO:0015031	345	0.017	Human Mouse
cell surface receptor signaling pathway	GO:0007166	38	0.017
ribonucleoside metabolic process	GO:0009119	389	0.017
regulation of cellular component biogenesis	GO:0044087	112	0.017
single organism membrane organization	GO:0044802	275	0.016
protein import into nucleus	GO:0006606	55	0.016
cellular response to extracellular stimulus	GO:0031668	150	0.016
single organism reproductive process	GO:0044702	159	0.016
negative regulation of protein metabolic process	GO:0051248	85	0.016
negative regulation of transport	GO:0051051	15	0.015	Human
negative regulation of phosphorus metabolic process	GO:0010563	49	0.015	Human Mouse
protein localization to nucleus	GO:0034504	74	0.015
positive regulation of protein metabolic process	GO:0051247	93	0.015
glycosyl compound metabolic process	GO:1901657	398	0.015
purine containing compound biosynthetic process	GO:0072522	53	0.014
nuclear transport	GO:0051169	165	0.014	Mouse
response to organic substance	GO:0010033	182	0.014
regulation of generation of precursor metabolites and energy	GO:0043467	23	0.014
organelle localization	GO:0051640	128	0.013
microtubule depolymerization	GO:0007019	8	0.013
positive regulation of cellular protein metabolic process	GO:0032270	89	0.013
eisosome assembly	GO:0070941	8	0.013
cellular response to starvation	GO:0009267	90	0.013
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.013
cytokinetic process	GO:0032506	78	0.013
glycerolipid biosynthetic process	GO:0045017	71	0.013
cellular component macromolecule biosynthetic process	GO:0070589	24	0.013
regulation of endocytosis	GO:0030100	17	0.013
organic cyclic compound catabolic process	GO:1901361	499	0.013
protein dna complex subunit organization	GO:0071824	153	0.013
dna damage checkpoint	GO:0000077	29	0.012
cell wall macromolecule metabolic process	GO:0044036	27	0.012
response to monosaccharide	GO:0034284	13	0.012
organelle assembly	GO:0070925	118	0.012
cell wall polysaccharide metabolic process	GO:0010383	17	0.011
cellular carbohydrate biosynthetic process	GO:0034637	49	0.011
nucleotide metabolic process	GO:0009117	453	0.011
lipid modification	GO:0030258	37	0.011
ribonucleoside catabolic process	GO:0042454	332	0.011
purine containing compound catabolic process	GO:0072523	332	0.011
positive regulation of transcription dna templated	GO:0045893	286	0.011
cellular respiration	GO:0045333	82	0.011
peptidyl amino acid modification	GO:0018193	116	0.011
anatomical structure homeostasis	GO:0060249	74	0.011
pyruvate metabolic process	GO:0006090	37	0.011
nucleobase containing small molecule metabolic process	GO:0055086	491	0.011
rrna metabolic process	GO:0016072	244	0.011
purine nucleotide biosynthetic process	GO:0006164	41	0.011
cellular nitrogen compound catabolic process	GO:0044270	494	0.011
positive regulation of intracellular signal transduction	GO:1902533	16	0.011	Fly
histone modification	GO:0016570	119	0.010
positive regulation of secretion	GO:0051047	2	0.010
purine ribonucleoside catabolic process	GO:0046130	330	0.010
positive regulation of cytoplasmic transport	GO:1903651	4	0.010	Mouse
response to abiotic stimulus	GO:0009628	159	0.010	Fly

BMH2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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