| mrna metabolic process | GO:0016071 | 269 | 0.987 | |
| nuclear transcribed mrna catabolic process | GO:0000956 | 89 | 0.969 | Yeast |
| rna catabolic process | GO:0006401 | 118 | 0.933 | Yeast |
| cellular macromolecule catabolic process | GO:0044265 | 363 | 0.911 | Yeast |
| regulation of protein metabolic process | GO:0051246 | 237 | 0.874 | |
| negative regulation of gene expression | GO:0010629 | 312 | 0.778 | |
| regulation of cellular protein metabolic process | GO:0032268 | 232 | 0.728 | |
| gene silencing | GO:0016458 | 151 | 0.704 | |
| mrna catabolic process | GO:0006402 | 93 | 0.650 | Yeast |
| macromolecule catabolic process | GO:0009057 | 383 | 0.565 | Yeast |
| mrna processing | GO:0006397 | 185 | 0.558 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 115 | 0.530 | |
| ribonucleoprotein complex assembly | GO:0022618 | 143 | 0.496 | Human |
| organic cyclic compound catabolic process | GO:1901361 | 499 | 0.492 | Yeast |
| dna templated transcription elongation | GO:0006354 | 91 | 0.452 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 289 | 0.449 | |
| aromatic compound catabolic process | GO:0019439 | 491 | 0.444 | Yeast |
| positive regulation of rna metabolic process | GO:0051254 | 294 | 0.388 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 152 | 0.374 | Human |
| positive regulation of macromolecule metabolic process | GO:0010604 | 394 | 0.361 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 312 | 0.331 | |
| negative regulation of biosynthetic process | GO:0009890 | 312 | 0.328 | |
| single organism membrane organization | GO:0044802 | 275 | 0.305 | |
| establishment of rna localization | GO:0051236 | 92 | 0.293 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 494 | 0.288 | Yeast |
| positive regulation of biosynthetic process | GO:0009891 | 336 | 0.274 | |
| nucleobase containing compound catabolic process | GO:0034655 | 479 | 0.267 | Yeast |
| translation | GO:0006412 | 230 | 0.261 | |
| oxoacid metabolic process | GO:0043436 | 351 | 0.260 | |
| developmental process | GO:0032502 | 261 | 0.254 | Mouse Worm Fly |
| positive regulation of gene expression | GO:0010628 | 321 | 0.243 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 291 | 0.231 | |
| regulation of phosphorus metabolic process | GO:0051174 | 230 | 0.225 | |
| modification dependent macromolecule catabolic process | GO:0043632 | 203 | 0.224 | |
| organelle fission | GO:0048285 | 272 | 0.209 | |
| carboxylic acid biosynthetic process | GO:0046394 | 152 | 0.208 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 412 | 0.200 | |
| regulation of cell cycle | GO:0051726 | 195 | 0.190 | Fly |
| cellular amino acid metabolic process | GO:0006520 | 225 | 0.185 | |
| positive regulation of transcription dna templated | GO:0045893 | 286 | 0.178 | |
| regulation of translation | GO:0006417 | 89 | 0.176 | |
| rna localization | GO:0006403 | 112 | 0.172 | |
| transcription elongation from rna polymerase ii promoter | GO:0006368 | 81 | 0.168 | |
| regulation of gene expression epigenetic | GO:0040029 | 147 | 0.154 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 147 | 0.153 | |
| regulation of protein modification process | GO:0031399 | 110 | 0.140 | |
| histone modification | GO:0016570 | 119 | 0.131 | |
| negative regulation of rna metabolic process | GO:0051253 | 262 | 0.127 | |
| ncrna 3 end processing | GO:0043628 | 44 | 0.124 | |
| nitrogen compound transport | GO:0071705 | 212 | 0.123 | |
| organelle assembly | GO:0070925 | 118 | 0.120 | |
| negative regulation of protein metabolic process | GO:0051248 | 85 | 0.118 | |
| rna 3 end processing | GO:0031123 | 88 | 0.117 | |
| snorna metabolic process | GO:0016074 | 40 | 0.112 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 375 | 0.097 | |
| nuclear export | GO:0051168 | 124 | 0.095 | |
| negative regulation of cellular protein metabolic process | GO:0032269 | 85 | 0.094 | |
| regulation of phosphate metabolic process | GO:0019220 | 230 | 0.093 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 286 | 0.093 | |
| nuclear division | GO:0000280 | 263 | 0.088 | |
| cellular amine metabolic process | GO:0044106 | 51 | 0.086 | |
| chromatin silencing at telomere | GO:0006348 | 84 | 0.085 | |
| membrane organization | GO:0061024 | 276 | 0.082 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 286 | 0.079 | |
| organic acid metabolic process | GO:0006082 | 352 | 0.076 | |
| regulation of response to stimulus | GO:0048583 | 157 | 0.076 | |
| meiotic nuclear division | GO:0007126 | 163 | 0.076 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 42 | 0.072 | |
| response to chemical | GO:0042221 | 390 | 0.069 | |
| serine family amino acid metabolic process | GO:0009069 | 25 | 0.068 | |
| nucleobase containing compound transport | GO:0015931 | 124 | 0.067 | |
| chromatin silencing | GO:0006342 | 147 | 0.067 | |
| nucleic acid phosphodiester bond hydrolysis | GO:0090305 | 194 | 0.066 | |
| cellular ketone metabolic process | GO:0042180 | 63 | 0.064 | |
| covalent chromatin modification | GO:0016569 | 119 | 0.062 | |
| mrna transport | GO:0051028 | 60 | 0.060 | |
| protein ubiquitination | GO:0016567 | 118 | 0.059 | |
| negative regulation of cellular metabolic process | GO:0031324 | 407 | 0.058 | |
| single organism developmental process | GO:0044767 | 258 | 0.052 | Mouse Worm Fly |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 409 | 0.051 | |
| regulation of protein complex assembly | GO:0043254 | 77 | 0.051 | |
| glycerolipid metabolic process | GO:0046486 | 108 | 0.050 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 295 | 0.049 | |
| cellular response to chemical stimulus | GO:0070887 | 315 | 0.049 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 336 | 0.048 | |
| heterocycle catabolic process | GO:0046700 | 494 | 0.048 | Yeast |
| carboxylic acid metabolic process | GO:0019752 | 338 | 0.046 | |
| positive regulation of programmed cell death | GO:0043068 | 3 | 0.046 | |
| establishment of protein localization to membrane | GO:0090150 | 99 | 0.046 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 300 | 0.045 | |
| anatomical structure development | GO:0048856 | 160 | 0.044 | Mouse Worm Fly |
| gene silencing by rna | GO:0031047 | 3 | 0.043 | |
| rna splicing via transesterification reactions | GO:0000375 | 118 | 0.043 | |
| rna transport | GO:0050658 | 92 | 0.041 | |
| mrna 3 end processing | GO:0031124 | 54 | 0.041 | |
| regulation of cellular component organization | GO:0051128 | 334 | 0.039 | |
| nuclear transport | GO:0051169 | 165 | 0.038 | |
| mitotic cell cycle | GO:0000278 | 306 | 0.038 | Fly |
| nucleocytoplasmic transport | GO:0006913 | 163 | 0.034 | |
| regulation of transcription elongation from rna polymerase ii promoter | GO:0034243 | 40 | 0.034 | |
| negative regulation of transcription dna templated | GO:0045892 | 258 | 0.033 | |
| regulation of translational elongation | GO:0006448 | 25 | 0.033 | |
| nuclear transcribed mrna catabolic process nonsense mediated decay | GO:0000184 | 15 | 0.033 | |
| amine metabolic process | GO:0009308 | 51 | 0.032 | |
| regulation of cell cycle process | GO:0010564 | 150 | 0.031 | Fly |
| positive regulation of dna templated transcription elongation | GO:0032786 | 42 | 0.031 | |
| snorna processing | GO:0043144 | 34 | 0.031 | |
| dna replication | GO:0006260 | 147 | 0.029 | |
| lipid metabolic process | GO:0006629 | 269 | 0.029 | |
| mitochondrion organization | GO:0007005 | 261 | 0.027 | |
| rna export from nucleus | GO:0006405 | 88 | 0.027 | |
| meiotic cell cycle | GO:0051321 | 272 | 0.026 | |
| protein localization to membrane | GO:0072657 | 102 | 0.026 | |
| single organism catabolic process | GO:0044712 | 619 | 0.026 | |
| intracellular mrna localization | GO:0008298 | 23 | 0.025 | |
| protein localization to organelle | GO:0033365 | 337 | 0.025 | |
| nucleic acid transport | GO:0050657 | 94 | 0.025 | |
| negative regulation of protein modification process | GO:0031400 | 37 | 0.023 | |
| poly a mrna export from nucleus | GO:0016973 | 24 | 0.023 | Yeast |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 325 | 0.022 | |
| regulation of response to stress | GO:0080134 | 57 | 0.022 | |
| small molecule biosynthetic process | GO:0044283 | 258 | 0.021 | |
| regulation of biological quality | GO:0065008 | 391 | 0.021 | |
| regulation of signaling | GO:0023051 | 119 | 0.021 | |
| translational elongation | GO:0006414 | 32 | 0.021 | |
| positive regulation of cell death | GO:0010942 | 3 | 0.020 | |
| regulation of signal transduction | GO:0009966 | 114 | 0.020 | |
| multi organism process | GO:0051704 | 233 | 0.020 | |
| cytoplasmic translation | GO:0002181 | 65 | 0.020 | |
| chromosome segregation | GO:0007059 | 159 | 0.020 | |
| mrna splicing via spliceosome | GO:0000398 | 108 | 0.020 | |
| ribonucleoside catabolic process | GO:0042454 | 332 | 0.020 | |
| anatomical structure morphogenesis | GO:0009653 | 160 | 0.019 | |
| chromatin modification | GO:0016568 | 200 | 0.018 | |
| dna dependent dna replication | GO:0006261 | 115 | 0.018 | |
| rna surveillance | GO:0071025 | 30 | 0.017 | Yeast |
| positive regulation of protein metabolic process | GO:0051247 | 93 | 0.016 | |
| regulation of dna templated transcription elongation | GO:0032784 | 44 | 0.016 | |
| positive regulation of apoptotic process | GO:0043065 | 3 | 0.016 | |
| regulation of hydrolase activity | GO:0051336 | 133 | 0.015 | |
| regulation of catabolic process | GO:0009894 | 199 | 0.015 | |
| endomembrane system organization | GO:0010256 | 74 | 0.015 | |
| chromatin organization | GO:0006325 | 242 | 0.014 | |
| establishment of protein localization to organelle | GO:0072594 | 278 | 0.014 | |
| positive regulation of translation | GO:0045727 | 34 | 0.014 | |
| developmental process involved in reproduction | GO:0003006 | 159 | 0.014 | Worm |
| regulation of cellular amine metabolic process | GO:0033238 | 21 | 0.014 | |
| negative regulation of cell cycle | GO:0045786 | 91 | 0.014 | Fly |
| rna phosphodiester bond hydrolysis | GO:0090501 | 112 | 0.013 | |
| positive regulation of cellular component organization | GO:0051130 | 116 | 0.013 | |
| cellular developmental process | GO:0048869 | 191 | 0.013 | Fly |
| negative regulation of rna biosynthetic process | GO:1902679 | 260 | 0.013 | |
| regulation of carbohydrate metabolic process | GO:0006109 | 43 | 0.013 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 16 | 0.013 | |
| regulation of mrna splicing via spliceosome | GO:0048024 | 3 | 0.013 | Human |
| maturation of 5 8s rrna | GO:0000460 | 80 | 0.013 | |
| regulation of cellular component biogenesis | GO:0044087 | 112 | 0.012 | |
| establishment of protein localization | GO:0045184 | 367 | 0.012 | |
| regulation of organelle organization | GO:0033043 | 243 | 0.012 | |
| monosaccharide metabolic process | GO:0005996 | 83 | 0.012 | |
| regulation of rna splicing | GO:0043484 | 3 | 0.012 | Human |
| single organism carbohydrate metabolic process | GO:0044723 | 237 | 0.011 | |
| ncrna processing | GO:0034470 | 330 | 0.011 | |
| rna polyadenylation | GO:0043631 | 26 | 0.011 | |
| organic acid biosynthetic process | GO:0016053 | 152 | 0.011 | |
| chromatin remodeling | GO:0006338 | 80 | 0.011 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 89 | 0.010 | |
| proteolysis | GO:0006508 | 268 | 0.010 | |