| protein acetylation | GO:0006473 | 59 | 1.000 | |
| histone modification | GO:0016570 | 119 | 1.000 | |
| covalent chromatin modification | GO:0016569 | 119 | 0.999 | |
| chromatin modification | GO:0016568 | 200 | 0.999 | |
| peptidyl lysine modification | GO:0018205 | 77 | 0.998 | |
| chromatin organization | GO:0006325 | 242 | 0.998 | |
| peptidyl lysine acetylation | GO:0018394 | 52 | 0.998 | |
| internal protein amino acid acetylation | GO:0006475 | 52 | 0.998 | |
| internal peptidyl lysine acetylation | GO:0018393 | 52 | 0.996 | |
| protein acylation | GO:0043543 | 66 | 0.995 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 394 | 0.991 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 252 | 0.988 | |
| histone acetylation | GO:0016573 | 51 | 0.987 | |
| peptidyl amino acid modification | GO:0018193 | 116 | 0.985 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 412 | 0.965 | |
| positive regulation of rna metabolic process | GO:0051254 | 294 | 0.947 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 286 | 0.940 | |
| positive regulation of rna biosynthetic process | GO:1902680 | 286 | 0.935 | |
| positive regulation of transcription dna templated | GO:0045893 | 286 | 0.930 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 325 | 0.924 | |
| positive regulation of biosynthetic process | GO:0009891 | 336 | 0.914 | |
| histone deubiquitination | GO:0016578 | 6 | 0.903 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 409 | 0.854 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 336 | 0.838 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 394 | 0.813 | |
| positive regulation of gene expression | GO:0010628 | 321 | 0.780 | |
| negative regulation of transcription dna templated | GO:0045892 | 258 | 0.667 | |
| histone h3 acetylation | GO:0043966 | 5 | 0.650 | Fly |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 300 | 0.608 | |
| negative regulation of rna metabolic process | GO:0051253 | 262 | 0.601 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 137 | 0.580 | |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 55 | 0.575 | |
| chromatin remodeling | GO:0006338 | 80 | 0.559 | Fly |
| negative regulation of biosynthetic process | GO:0009890 | 312 | 0.484 | |
| protein deubiquitination | GO:0016579 | 17 | 0.423 | |
| negative regulation of macromolecule metabolic process | GO:0010605 | 375 | 0.387 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 260 | 0.355 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 295 | 0.279 | |
| negative regulation of gene expression | GO:0010629 | 312 | 0.277 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 291 | 0.245 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 40 | 0.245 | |
| atp dependent chromatin remodeling | GO:0043044 | 36 | 0.245 | |
| cell communication | GO:0007154 | 345 | 0.241 | Fly |
| pseudohyphal growth | GO:0007124 | 75 | 0.228 | |
| mrna metabolic process | GO:0016071 | 269 | 0.219 | |
| mitotic cell cycle process | GO:1903047 | 294 | 0.217 | |
| cellular response to chemical stimulus | GO:0070887 | 315 | 0.212 | |
| protein dna complex subunit organization | GO:0071824 | 153 | 0.207 | |
| dna repair | GO:0006281 | 236 | 0.191 | |
| regulation of phosphate metabolic process | GO:0019220 | 230 | 0.178 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 289 | 0.171 | |
| regulation of chromatin modification | GO:1903308 | 23 | 0.158 | |
| positive regulation of phosphate metabolic process | GO:0045937 | 147 | 0.155 | |
| histone exchange | GO:0043486 | 18 | 0.152 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 260 | 0.148 | |
| regulation of phosphorus metabolic process | GO:0051174 | 230 | 0.138 | |
| positive regulation of phosphorus metabolic process | GO:0010562 | 147 | 0.136 | |
| regulation of histone exchange | GO:1900049 | 4 | 0.135 | |
| signal transduction | GO:0007165 | 208 | 0.126 | |
| negative regulation of cell cycle | GO:0045786 | 91 | 0.125 | |
| positive regulation of cellular component biogenesis | GO:0044089 | 45 | 0.123 | |
| nuclear export | GO:0051168 | 124 | 0.121 | |
| protein modification by small protein removal | GO:0070646 | 29 | 0.115 | |
| mrna processing | GO:0006397 | 185 | 0.114 | |
| filamentous growth of a population of unicellular organisms | GO:0044182 | 109 | 0.112 | |
| chromatin silencing | GO:0006342 | 147 | 0.106 | |
| filamentous growth | GO:0030447 | 124 | 0.105 | |
| growth of unicellular organism as a thread of attached cells | GO:0070783 | 105 | 0.102 | |
| regulation of transcription by chromatin organization | GO:0034401 | 19 | 0.099 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 68 | 0.093 | |
| regulation of cell cycle | GO:0051726 | 195 | 0.090 | |
| protein modification by small protein conjugation or removal | GO:0070647 | 172 | 0.090 | |
| chromatin silencing at silent mating type cassette | GO:0030466 | 53 | 0.088 | |
| negative regulation of chromatin modification | GO:1903309 | 9 | 0.087 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 59 | 0.083 | |
| regulation of phosphorylation | GO:0042325 | 86 | 0.080 | |
| signaling | GO:0023052 | 208 | 0.080 | |
| negative regulation of mitotic cell cycle | GO:0045930 | 63 | 0.079 | |
| dna templated transcription initiation | GO:0006352 | 71 | 0.077 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 312 | 0.076 | |
| regulation of transcription initiation from rna polymerase ii promoter | GO:0060260 | 19 | 0.076 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 181 | 0.076 | |
| negative regulation of mitotic cell cycle phase transition | GO:1901991 | 57 | 0.075 | |
| response to chemical | GO:0042221 | 390 | 0.074 | |
| mitotic cell cycle | GO:0000278 | 306 | 0.070 | |
| mrna catabolic process | GO:0006402 | 93 | 0.070 | |
| protein dna complex assembly | GO:0065004 | 105 | 0.069 | |
| regulation of cell cycle process | GO:0010564 | 150 | 0.065 | |
| dna templated transcription elongation | GO:0006354 | 91 | 0.064 | |
| regulation of biological quality | GO:0065008 | 391 | 0.063 | |
| growth | GO:0040007 | 157 | 0.063 | |
| multi organism cellular process | GO:0044764 | 120 | 0.062 | |
| cell cycle checkpoint | GO:0000075 | 82 | 0.062 | |
| cellular response to organic substance | GO:0071310 | 159 | 0.061 | |
| sporulation resulting in formation of a cellular spore | GO:0030435 | 129 | 0.061 | |
| dna templated transcriptional preinitiation complex assembly | GO:0070897 | 51 | 0.057 | |
| negative regulation of cellular metabolic process | GO:0031324 | 407 | 0.056 | |
| regulation of cellular component organization | GO:0051128 | 334 | 0.055 | |
| positive regulation of transcription initiation from rna polymerase ii promoter | GO:0060261 | 13 | 0.054 | |
| regulation of cellular component biogenesis | GO:0044087 | 112 | 0.053 | |
| invasive filamentous growth | GO:0036267 | 65 | 0.051 | |
| heterocycle catabolic process | GO:0046700 | 494 | 0.049 | |
| multi organism reproductive process | GO:0044703 | 216 | 0.049 | |
| regulation of dna templated transcription initiation | GO:2000142 | 19 | 0.045 | |
| single organism signaling | GO:0044700 | 208 | 0.044 | |
| cellular response to nutrient levels | GO:0031669 | 144 | 0.043 | |
| regulation of protein complex assembly | GO:0043254 | 77 | 0.042 | |
| response to topologically incorrect protein | GO:0035966 | 38 | 0.042 | |
| nuclear rna surveillance | GO:0071027 | 30 | 0.041 | |
| regulation of localization | GO:0032879 | 127 | 0.040 | |
| negative regulation of chromosome organization | GO:2001251 | 39 | 0.040 | |
| gene silencing | GO:0016458 | 151 | 0.040 | |
| transcription dependent tethering of rna polymerase ii gene dna at nuclear periphery | GO:0000972 | 19 | 0.039 | |
| negative regulation of organelle organization | GO:0010639 | 103 | 0.038 | |
| rna transport | GO:0050658 | 92 | 0.038 | |
| cell growth | GO:0016049 | 89 | 0.037 | |
| cell cycle phase transition | GO:0044770 | 144 | 0.037 | |
| protein glycosylation | GO:0006486 | 57 | 0.037 | |
| nucleobase containing compound transport | GO:0015931 | 124 | 0.036 | |
| glycoprotein biosynthetic process | GO:0009101 | 61 | 0.036 | |
| polysaccharide metabolic process | GO:0005976 | 60 | 0.035 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 42 | 0.034 | |
| monosaccharide metabolic process | GO:0005996 | 83 | 0.034 | |
| transcription elongation from rna polymerase ii promoter | GO:0006368 | 81 | 0.033 | |
| positive regulation of organelle organization | GO:0010638 | 85 | 0.033 | |
| regulation of chromatin silencing | GO:0031935 | 39 | 0.033 | |
| rna localization | GO:0006403 | 112 | 0.033 | |
| single organism carbohydrate metabolic process | GO:0044723 | 237 | 0.033 | |
| nucleobase containing small molecule metabolic process | GO:0055086 | 491 | 0.033 | |
| response to organic substance | GO:0010033 | 182 | 0.033 | |
| positive regulation of catalytic activity | GO:0043085 | 178 | 0.032 | |
| aromatic compound catabolic process | GO:0019439 | 491 | 0.032 | |
| regulation of protein metabolic process | GO:0051246 | 237 | 0.032 | |
| regulation of cell cycle phase transition | GO:1901987 | 70 | 0.032 | |
| negative regulation of dna metabolic process | GO:0051053 | 36 | 0.032 | |
| regulation of chromatin silencing at silent mating type cassette | GO:0090054 | 13 | 0.032 | |
| regulation of cellular protein metabolic process | GO:0032268 | 232 | 0.031 | |
| rna splicing | GO:0008380 | 131 | 0.031 | |
| response to external stimulus | GO:0009605 | 158 | 0.031 | |
| regulation of protein modification process | GO:0031399 | 110 | 0.031 | |
| macromolecule glycosylation | GO:0043413 | 57 | 0.031 | |
| response to extracellular stimulus | GO:0009991 | 156 | 0.030 | |
| chromatin silencing at rdna | GO:0000183 | 32 | 0.030 | |
| protein transport | GO:0015031 | 345 | 0.030 | |
| chromatin assembly or disassembly | GO:0006333 | 60 | 0.030 | |
| macromolecule catabolic process | GO:0009057 | 383 | 0.030 | |
| cytoskeleton dependent cytokinesis | GO:0061640 | 65 | 0.029 | |
| rna surveillance | GO:0071025 | 30 | 0.029 | |
| histone methylation | GO:0016571 | 28 | 0.029 | |
| invasive growth in response to glucose limitation | GO:0001403 | 61 | 0.029 | |
| protein complex assembly | GO:0006461 | 302 | 0.029 | |
| response to oxidative stress | GO:0006979 | 99 | 0.028 | |
| cellular response to extracellular stimulus | GO:0031668 | 150 | 0.028 | |
| positive regulation of rna polymerase ii transcriptional preinitiation complex assembly | GO:0045899 | 11 | 0.028 | |
| regulation of organelle organization | GO:0033043 | 243 | 0.027 | |
| mitotic cell cycle phase transition | GO:0044772 | 141 | 0.027 | |
| meiotic cell cycle | GO:0051321 | 272 | 0.027 | |
| response to reactive oxygen species | GO:0000302 | 22 | 0.027 | |
| cellular response to oxidative stress | GO:0034599 | 94 | 0.027 | |
| cellular macromolecule catabolic process | GO:0044265 | 363 | 0.027 | |
| cellular ketone metabolic process | GO:0042180 | 63 | 0.026 | |
| positive regulation of transcription elongation from rna polymerase ii promoter | GO:0032968 | 38 | 0.026 | |
| positive regulation of dna templated transcription initiation | GO:2000144 | 13 | 0.026 | |
| rna export from nucleus | GO:0006405 | 88 | 0.025 | |
| anatomical structure formation involved in morphogenesis | GO:0048646 | 136 | 0.025 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 494 | 0.025 | |
| organonitrogen compound catabolic process | GO:1901565 | 404 | 0.025 | |
| positive regulation of protein modification process | GO:0031401 | 49 | 0.025 | |
| positive regulation of molecular function | GO:0044093 | 185 | 0.025 | |
| regulation of catalytic activity | GO:0050790 | 307 | 0.025 | |
| heterochromatin organization | GO:0070828 | 11 | 0.024 | |
| regulation of molecular function | GO:0065009 | 320 | 0.024 | |
| cellular carbohydrate metabolic process | GO:0044262 | 135 | 0.024 | |
| glycoprotein metabolic process | GO:0009100 | 62 | 0.024 | |
| carbohydrate derivative metabolic process | GO:1901135 | 549 | 0.023 | |
| single organism developmental process | GO:0044767 | 258 | 0.023 | Fly |
| regulation of chromosome organization | GO:0033044 | 66 | 0.023 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 147 | 0.023 | |
| n terminal protein amino acid acetylation | GO:0006474 | 8 | 0.023 | |
| carbohydrate metabolic process | GO:0005975 | 252 | 0.023 | |
| cell division | GO:0051301 | 205 | 0.023 | |
| carbohydrate biosynthetic process | GO:0016051 | 82 | 0.023 | |
| negative regulation of cell cycle process | GO:0010948 | 86 | 0.022 | |
| response to nutrient levels | GO:0031667 | 150 | 0.022 | |
| regulation of chromatin silencing at telomere | GO:0031938 | 27 | 0.022 | |
| mrna export from nucleus | GO:0006406 | 60 | 0.021 | |
| positive regulation of cell death | GO:0010942 | 3 | 0.021 | |
| regulation of histone modification | GO:0031056 | 18 | 0.021 | |
| regulation of gene expression epigenetic | GO:0040029 | 147 | 0.021 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 115 | 0.020 | |
| regulation of cellular carbohydrate metabolic process | GO:0010675 | 41 | 0.020 | |
| multi organism process | GO:0051704 | 233 | 0.020 | |
| posttranscriptional tethering of rna polymerase ii gene dna at nuclear periphery | GO:0000973 | 16 | 0.020 | |
| histone h3 k4 methylation | GO:0051568 | 18 | 0.020 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 364 | 0.020 | |
| regulation of carbohydrate biosynthetic process | GO:0043255 | 31 | 0.020 | |
| hexose metabolic process | GO:0019318 | 78 | 0.020 | |
| conjugation with cellular fusion | GO:0000747 | 106 | 0.019 | |
| protein complex localization | GO:0031503 | 32 | 0.019 | |
| sexual reproduction | GO:0019953 | 216 | 0.019 | |
| carboxylic acid metabolic process | GO:0019752 | 338 | 0.019 | |
| response to unfolded protein | GO:0006986 | 29 | 0.019 | |
| sporulation | GO:0043934 | 132 | 0.019 | |
| mrna transport | GO:0051028 | 60 | 0.019 | |
| nuclear transcribed mrna catabolic process | GO:0000956 | 89 | 0.019 | |
| histone h3 k9 acetylation | GO:0043970 | 3 | 0.019 | |
| rna catabolic process | GO:0006401 | 118 | 0.019 | |
| response to endoplasmic reticulum stress | GO:0034976 | 23 | 0.019 | |
| organic cyclic compound catabolic process | GO:1901361 | 499 | 0.018 | |
| cellular amino acid metabolic process | GO:0006520 | 225 | 0.018 | |
| glucose metabolic process | GO:0006006 | 65 | 0.018 | |
| protein complex disassembly | GO:0043241 | 70 | 0.017 | |
| positive regulation of response to stimulus | GO:0048584 | 37 | 0.017 | |
| positive regulation of transferase activity | GO:0051347 | 28 | 0.017 | |
| double strand break repair via nonhomologous end joining | GO:0006303 | 27 | 0.017 | |
| regulation of cellular localization | GO:0060341 | 50 | 0.017 | |
| protein targeting | GO:0006605 | 272 | 0.016 | |
| single organism catabolic process | GO:0044712 | 619 | 0.016 | |
| regulation of transferase activity | GO:0051338 | 83 | 0.016 | |
| er nucleus signaling pathway | GO:0006984 | 23 | 0.016 | |
| nucleocytoplasmic transport | GO:0006913 | 163 | 0.016 | |
| reproduction of a single celled organism | GO:0032505 | 191 | 0.016 | |
| glycosylation | GO:0070085 | 66 | 0.016 | |
| ncrna processing | GO:0034470 | 330 | 0.016 | |
| regulation of gene silencing | GO:0060968 | 41 | 0.015 | |
| regulation of chromatin organization | GO:1902275 | 23 | 0.015 | |
| proteasome mediated ubiquitin dependent protein catabolic process | GO:0043161 | 137 | 0.015 | |
| cellular response to external stimulus | GO:0071496 | 150 | 0.015 | |
| regulation of mitotic cell cycle | GO:0007346 | 107 | 0.015 | |
| establishment of rna localization | GO:0051236 | 92 | 0.015 | |
| regulation of dna metabolic process | GO:0051052 | 100 | 0.015 | |
| protein methylation | GO:0006479 | 48 | 0.015 | |
| phosphorylation | GO:0016310 | 291 | 0.015 | |
| regulation of signal transduction | GO:0009966 | 114 | 0.015 | |
| regulation of cellular ketone metabolic process by positive regulation of transcription from rna polymerase ii promoter | GO:0072366 | 10 | 0.015 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 64 | 0.015 | |
| protein dna complex disassembly | GO:0032986 | 20 | 0.015 | |
| histone lysine methylation | GO:0034968 | 26 | 0.014 | |
| positive regulation of signal transduction | GO:0009967 | 20 | 0.014 | |
| regulation of glucose metabolic process | GO:0010906 | 27 | 0.014 | |
| macromolecule methylation | GO:0043414 | 85 | 0.014 | |
| replicative cell aging | GO:0001302 | 46 | 0.014 | |
| cellular bud site selection | GO:0000282 | 35 | 0.014 | |
| cellular response to unfolded protein | GO:0034620 | 23 | 0.014 | |
| negative regulation of chromatin silencing | GO:0031936 | 25 | 0.014 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 224 | 0.014 | |
| regulation of transport | GO:0051049 | 85 | 0.014 | |
| ion transport | GO:0006811 | 274 | 0.013 | |
| positive regulation of protein metabolic process | GO:0051247 | 93 | 0.013 | |
| mitotic dna integrity checkpoint | GO:0044774 | 18 | 0.013 | |
| mitotic cytokinesis | GO:0000281 | 58 | 0.013 | |
| single organism cellular localization | GO:1902580 | 375 | 0.013 | |
| iron ion transport | GO:0006826 | 18 | 0.013 | |
| regulation of cellular amino acid metabolic process | GO:0006521 | 16 | 0.013 | |
| regulation of filamentous growth of a population of unicellular organisms | GO:1900428 | 36 | 0.013 | |
| amine metabolic process | GO:0009308 | 51 | 0.013 | |
| ribonucleoside metabolic process | GO:0009119 | 389 | 0.013 | |
| protein processing | GO:0016485 | 64 | 0.013 | |
| regulation of cell division | GO:0051302 | 113 | 0.013 | |
| regulation of transcription elongation from rna polymerase ii promoter | GO:0034243 | 40 | 0.013 | |
| regulation of cellular amine metabolic process | GO:0033238 | 21 | 0.013 | |
| regulation of histone acetylation | GO:0035065 | 7 | 0.013 | |
| developmental process | GO:0032502 | 261 | 0.013 | Fly |
| macromolecular complex disassembly | GO:0032984 | 80 | 0.013 | |
| dna replication | GO:0006260 | 147 | 0.013 | |
| alcohol biosynthetic process | GO:0046165 | 75 | 0.012 | |
| regulation of growth of unicellular organism as a thread of attached cells | GO:0070784 | 31 | 0.012 | |
| mitotic cytokinetic process | GO:1902410 | 45 | 0.012 | |
| positive regulation of transcription from rna polymerase ii promoter in response to stress | GO:0036003 | 33 | 0.012 | |
| intracellular protein transport | GO:0006886 | 319 | 0.012 | |
| cellular amine metabolic process | GO:0044106 | 51 | 0.012 | |
| positive regulation of cellular component organization | GO:0051130 | 116 | 0.012 | |
| nucleoside phosphate metabolic process | GO:0006753 | 458 | 0.012 | |
| positive regulation of cell communication | GO:0010647 | 28 | 0.012 | |
| regulation of cell communication | GO:0010646 | 124 | 0.012 | |
| response to oxygen containing compound | GO:1901700 | 61 | 0.012 | |
| positive regulation of programmed cell death | GO:0043068 | 3 | 0.011 | |
| response to inorganic substance | GO:0010035 | 47 | 0.011 | |
| ribosomal small subunit biogenesis | GO:0042274 | 124 | 0.011 | |
| positive regulation of sequence specific dna binding transcription factor activity | GO:0051091 | 2 | 0.011 | |
| meiotic nuclear division | GO:0007126 | 163 | 0.011 | |
| cellular response to dna damage stimulus | GO:0006974 | 287 | 0.011 | |
| regulation of kinase activity | GO:0043549 | 71 | 0.011 | |
| sexual sporulation resulting in formation of a cellular spore | GO:0043935 | 113 | 0.011 | |
| regulation of rna splicing | GO:0043484 | 3 | 0.011 | |
| methylation | GO:0032259 | 101 | 0.011 | |
| nuclear transport | GO:0051169 | 165 | 0.011 | |
| regulation of signaling | GO:0023051 | 119 | 0.011 | |
| histone ubiquitination | GO:0016574 | 17 | 0.011 | |
| asexual reproduction | GO:0019954 | 48 | 0.011 | |
| cellular response to nutrient | GO:0031670 | 50 | 0.011 | |
| carbohydrate derivative catabolic process | GO:1901136 | 339 | 0.011 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 89 | 0.010 | |
| endoplasmic reticulum unfolded protein response | GO:0030968 | 23 | 0.010 | |
| positive regulation of hydrolase activity | GO:0051345 | 112 | 0.010 | |
