IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

108 known processes

SPO16 (YHR153C)

Spo16p

Entrez: 856558
SGD: S000001196
UniProtKB: P17122

Process Predictions
Disease Predictions

SPO16 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
meiotic cell cycle process	GO:1903046	229	0.670
meiotic cell cycle	GO:0051321	272	0.576
nuclear division	GO:0000280	263	0.445
meiotic nuclear division	GO:0007126	163	0.428
dna recombination	GO:0006310	172	0.411
reproduction of a single celled organism	GO:0032505	191	0.397
meiosis i	GO:0007127	92	0.375
organelle fission	GO:0048285	272	0.259
dna repair	GO:0006281	236	0.149
cellular response to dna damage stimulus	GO:0006974	287	0.149
chromosome segregation	GO:0007059	159	0.133
double strand break repair	GO:0006302	105	0.129
negative regulation of biosynthetic process	GO:0009890	312	0.109
sexual reproduction	GO:0019953	216	0.107
fungal type cell wall organization	GO:0031505	145	0.097
single organism reproductive process	GO:0044702	159	0.096
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.091
external encapsulating structure organization	GO:0045229	146	0.091
cellular macromolecule catabolic process	GO:0044265	363	0.091
reciprocal meiotic recombination	GO:0007131	54	0.082
maintenance of dna repeat elements	GO:0043570	20	0.081
macromolecule catabolic process	GO:0009057	383	0.077
cell differentiation	GO:0030154	161	0.076
regulation of meiotic cell cycle	GO:0051445	43	0.075
negative regulation of meiosis	GO:0045835	23	0.073
regulation of meiosis	GO:0040020	42	0.071
synapsis	GO:0007129	19	0.070
ascospore formation	GO:0030437	107	0.070
cell communication	GO:0007154	345	0.069
reproductive process	GO:0022414	248	0.067
cell division	GO:0051301	205	0.066
reciprocal dna recombination	GO:0035825	54	0.065
establishment of protein localization	GO:0045184	367	0.063
oxoacid metabolic process	GO:0043436	351	0.062
regulation of organelle organization	GO:0033043	243	0.062
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.061
multi organism reproductive process	GO:0044703	216	0.061
anatomical structure development	GO:0048856	160	0.059
reproductive process in single celled organism	GO:0022413	145	0.058
carbohydrate derivative metabolic process	GO:1901135	549	0.056
organonitrogen compound biosynthetic process	GO:1901566	314	0.055
signal transduction	GO:0007165	208	0.055
mitotic sister chromatid segregation	GO:0000070	85	0.053
recombinational repair	GO:0000725	64	0.053
negative regulation of cellular metabolic process	GO:0031324	407	0.052
single organism cellular localization	GO:1902580	375	0.052
positive regulation of macromolecule metabolic process	GO:0010604	394	0.051
developmental process involved in reproduction	GO:0003006	159	0.051
double strand break repair via homologous recombination	GO:0000724	54	0.051
single organism developmental process	GO:0044767	258	0.051
single organism catabolic process	GO:0044712	619	0.050
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.050
cell development	GO:0048468	107	0.048
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.048
telomere maintenance	GO:0000723	74	0.046
negative regulation of macromolecule metabolic process	GO:0010605	375	0.045
single organism membrane organization	GO:0044802	275	0.044
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.044
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.044
homeostatic process	GO:0042592	227	0.043
cellular amino acid metabolic process	GO:0006520	225	0.042
anatomical structure morphogenesis	GO:0009653	160	0.041
negative regulation of rna metabolic process	GO:0051253	262	0.041
carboxylic acid metabolic process	GO:0019752	338	0.041
multi organism process	GO:0051704	233	0.041
mitotic cell cycle	GO:0000278	306	0.039
nucleoside phosphate metabolic process	GO:0006753	458	0.038
membrane organization	GO:0061024	276	0.037
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.037
developmental process	GO:0032502	261	0.037
organelle assembly	GO:0070925	118	0.037
cellular developmental process	GO:0048869	191	0.036
cell wall organization or biogenesis	GO:0071554	190	0.036
negative regulation of gene expression	GO:0010629	312	0.036
regulation of signaling	GO:0023051	119	0.035
regulation of biological quality	GO:0065008	391	0.035
cellular response to chemical stimulus	GO:0070887	315	0.034
carbohydrate metabolic process	GO:0005975	252	0.034
sexual sporulation	GO:0034293	113	0.033
mitotic cell cycle process	GO:1903047	294	0.033
protein transport	GO:0015031	345	0.033
regulation of catalytic activity	GO:0050790	307	0.033
mitotic nuclear division	GO:0007067	131	0.032
phosphorylation	GO:0016310	291	0.032
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.032
protein catabolic process	GO:0030163	221	0.032
synaptonemal complex organization	GO:0070193	16	0.032
regulation of dna metabolic process	GO:0051052	100	0.032
mitotic sister chromatid cohesion	GO:0007064	38	0.031
cellular component assembly involved in morphogenesis	GO:0010927	73	0.031
negative regulation of rna biosynthetic process	GO:1902679	260	0.031
protein modification by small protein conjugation	GO:0032446	144	0.031
meiotic chromosome segregation	GO:0045132	31	0.031
cellular protein catabolic process	GO:0044257	213	0.030
negative regulation of cellular biosynthetic process	GO:0031327	312	0.030
aromatic compound catabolic process	GO:0019439	491	0.030
chromatin silencing	GO:0006342	147	0.030
regulation of cellular component organization	GO:0051128	334	0.030
protein targeting	GO:0006605	272	0.030
generation of precursor metabolites and energy	GO:0006091	147	0.029
protein ubiquitination	GO:0016567	118	0.029
nucleobase containing small molecule metabolic process	GO:0055086	491	0.029
anatomical structure homeostasis	GO:0060249	74	0.029
amine metabolic process	GO:0009308	51	0.028
telomere organization	GO:0032200	75	0.028
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.028
nucleotide metabolic process	GO:0009117	453	0.028
cell cycle checkpoint	GO:0000075	82	0.028
signaling	GO:0023052	208	0.028
cellular amine metabolic process	GO:0044106	51	0.028
negative regulation of transcription dna templated	GO:0045892	258	0.027
regulation of cell division	GO:0051302	113	0.027
conjugation	GO:0000746	107	0.027
cellular component morphogenesis	GO:0032989	97	0.027
sporulation	GO:0043934	132	0.027
response to organic cyclic compound	GO:0014070	1	0.027
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.026
regulation of cell cycle process	GO:0010564	150	0.026
organophosphate biosynthetic process	GO:0090407	182	0.026
regulation of cell cycle	GO:0051726	195	0.026
intracellular signal transduction	GO:0035556	112	0.026
sister chromatid segregation	GO:0000819	93	0.026
establishment of mitotic sister chromatid cohesion	GO:0034087	15	0.026
organic cyclic compound catabolic process	GO:1901361	499	0.025
chromosome organization involved in meiosis	GO:0070192	32	0.025
regulation of catabolic process	GO:0009894	199	0.025
carbohydrate derivative biosynthetic process	GO:1901137	181	0.025
conjugation with cellular fusion	GO:0000747	106	0.025
mitotic recombination	GO:0006312	55	0.025
protein phosphorylation	GO:0006468	197	0.025
organophosphate metabolic process	GO:0019637	597	0.025
protein modification by small protein conjugation or removal	GO:0070647	172	0.025
regulation of signal transduction	GO:0009966	114	0.024
purine nucleotide metabolic process	GO:0006163	376	0.024
regulation of cellular catabolic process	GO:0031329	195	0.024
regulation of phosphorus metabolic process	GO:0051174	230	0.024
vacuolar transport	GO:0007034	145	0.023
budding cell bud growth	GO:0007117	29	0.023
nucleobase containing compound catabolic process	GO:0034655	479	0.023
response to abiotic stimulus	GO:0009628	159	0.023
cell budding	GO:0007114	48	0.023
mitotic chromosome condensation	GO:0007076	11	0.023
positive regulation of cellular protein metabolic process	GO:0032270	89	0.023
mitochondrion organization	GO:0007005	261	0.023
establishment of protein localization to organelle	GO:0072594	278	0.022
organic acid metabolic process	GO:0006082	352	0.022
single organism carbohydrate metabolic process	GO:0044723	237	0.022
response to organic substance	GO:0010033	182	0.022
organonitrogen compound catabolic process	GO:1901565	404	0.022
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.022
growth	GO:0040007	157	0.022
regulation of gene expression epigenetic	GO:0040029	147	0.022
meiotic mismatch repair	GO:0000710	9	0.022
protein dna complex assembly	GO:0065004	105	0.022
dna integrity checkpoint	GO:0031570	41	0.022
posttranscriptional regulation of gene expression	GO:0010608	115	0.021
regulation of protein metabolic process	GO:0051246	237	0.021
regulation of molecular function	GO:0065009	320	0.021
heterocycle catabolic process	GO:0046700	494	0.021
protein localization to organelle	GO:0033365	337	0.021
positive regulation of cellular biosynthetic process	GO:0031328	336	0.020
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.020
double strand break repair via synthesis dependent strand annealing	GO:0045003	12	0.020
dna recombinase assembly	GO:0000730	9	0.020
vesicle mediated transport	GO:0016192	335	0.020
organophosphate catabolic process	GO:0046434	338	0.020
positive regulation of cellular component organization	GO:0051130	116	0.020
negative regulation of cell cycle	GO:0045786	91	0.020
response to chemical	GO:0042221	390	0.020
positive regulation of catabolic process	GO:0009896	135	0.020
protein dna complex subunit organization	GO:0071824	153	0.020
glycosyl compound metabolic process	GO:1901657	398	0.020
autophagy	GO:0006914	106	0.020
chromosome condensation	GO:0030261	19	0.019
trna metabolic process	GO:0006399	151	0.019
single organism signaling	GO:0044700	208	0.019
carbohydrate derivative catabolic process	GO:1901136	339	0.019
cellular ketone metabolic process	GO:0042180	63	0.019
nucleoside catabolic process	GO:0009164	335	0.019
regulation of response to stimulus	GO:0048583	157	0.019
response to oxidative stress	GO:0006979	99	0.019
response to external stimulus	GO:0009605	158	0.019
hexose metabolic process	GO:0019318	78	0.018
positive regulation of programmed cell death	GO:0043068	3	0.018
nucleoside metabolic process	GO:0009116	394	0.018
response to extracellular stimulus	GO:0009991	156	0.018
cell cycle g1 s phase transition	GO:0044843	64	0.018
cellular response to external stimulus	GO:0071496	150	0.018
chromatin silencing at silent mating type cassette	GO:0030466	53	0.018
cellular response to nutrient levels	GO:0031669	144	0.018
intracellular protein transport	GO:0006886	319	0.018
glycosyl compound catabolic process	GO:1901658	335	0.018
regulation of cellular ketone metabolic process	GO:0010565	42	0.018
nucleic acid phosphodiester bond hydrolysis	GO:0090305	194	0.018
regulation of cellular protein metabolic process	GO:0032268	232	0.018
synaptonemal complex assembly	GO:0007130	12	0.018
ribonucleoside metabolic process	GO:0009119	389	0.018
ribonucleotide metabolic process	GO:0009259	377	0.018
purine ribonucleoside metabolic process	GO:0046128	380	0.018
positive regulation of protein metabolic process	GO:0051247	93	0.017
positive regulation of molecular function	GO:0044093	185	0.017
ribose phosphate metabolic process	GO:0019693	384	0.017
cell morphogenesis	GO:0000902	30	0.017
sister chromatid cohesion	GO:0007062	49	0.017
response to nutrient levels	GO:0031667	150	0.017
negative regulation of protein metabolic process	GO:0051248	85	0.017
negative regulation of phosphorylation	GO:0042326	28	0.017
cell wall organization	GO:0071555	146	0.017
protein autophosphorylation	GO:0046777	15	0.017
negative regulation of cell division	GO:0051782	66	0.017
pseudohyphal growth	GO:0007124	75	0.017
positive regulation of biosynthetic process	GO:0009891	336	0.017
chemical homeostasis	GO:0048878	137	0.016
mitochondrion localization	GO:0051646	29	0.016
negative regulation of cellular protein metabolic process	GO:0032269	85	0.016
cellular response to extracellular stimulus	GO:0031668	150	0.016
cellular amino acid biosynthetic process	GO:0008652	118	0.016
nucleoside triphosphate metabolic process	GO:0009141	364	0.016
regulation of dna replication	GO:0006275	51	0.016
purine ribonucleoside catabolic process	GO:0046130	330	0.016
endosomal transport	GO:0016197	86	0.016
dna packaging	GO:0006323	55	0.016
positive regulation of intracellular protein transport	GO:0090316	3	0.016
glycerolipid biosynthetic process	GO:0045017	71	0.016
response to starvation	GO:0042594	96	0.016
gene silencing	GO:0016458	151	0.016
filamentous growth	GO:0030447	124	0.015
chromatin modification	GO:0016568	200	0.015
negative regulation of nuclear division	GO:0051784	62	0.015
negative regulation of cell cycle process	GO:0010948	86	0.015
spore wall biogenesis	GO:0070590	52	0.015
glycerolipid metabolic process	GO:0046486	108	0.015
regulation of phosphate metabolic process	GO:0019220	230	0.015
negative regulation of protein modification process	GO:0031400	37	0.015
regulation of protein modification process	GO:0031399	110	0.015
cellular response to oxidative stress	GO:0034599	94	0.015
translation	GO:0006412	230	0.015
positive regulation of intracellular transport	GO:0032388	4	0.015
dna replication	GO:0006260	147	0.015
mrna processing	GO:0006397	185	0.015
macroautophagy	GO:0016236	55	0.015
single organism membrane fusion	GO:0044801	71	0.015
chromatin organization	GO:0006325	242	0.014
mrna 3 end processing	GO:0031124	54	0.014
regulation of cellular amino acid metabolic process	GO:0006521	16	0.014
chromatin silencing at telomere	GO:0006348	84	0.014
multi organism cellular process	GO:0044764	120	0.014
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.014
ribonucleotide catabolic process	GO:0009261	327	0.014
cellular response to organic substance	GO:0071310	159	0.014
chromosome separation	GO:0051304	33	0.014
regulation of nuclear division	GO:0051783	103	0.014
macromolecule methylation	GO:0043414	85	0.014
energy derivation by oxidation of organic compounds	GO:0015980	125	0.014
positive regulation of cell death	GO:0010942	3	0.014
alpha amino acid metabolic process	GO:1901605	124	0.014
protein complex biogenesis	GO:0070271	314	0.014
single organism carbohydrate catabolic process	GO:0044724	73	0.014
regulation of hydrolase activity	GO:0051336	133	0.014
nucleotide catabolic process	GO:0009166	330	0.013
cell growth	GO:0016049	89	0.013
regulation of cellular component biogenesis	GO:0044087	112	0.013
spindle pole body organization	GO:0051300	33	0.013
dna damage checkpoint	GO:0000077	29	0.013
regulation of dna dependent dna replication	GO:0090329	37	0.013
membrane lipid metabolic process	GO:0006643	67	0.013
negative regulation of dna metabolic process	GO:0051053	36	0.013
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.013
regulation of metaphase anaphase transition of cell cycle	GO:1902099	27	0.013
phospholipid biosynthetic process	GO:0008654	89	0.013
purine nucleoside catabolic process	GO:0006152	330	0.013
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.013
negative regulation of gene expression epigenetic	GO:0045814	147	0.013
protein complex assembly	GO:0006461	302	0.013
organelle inheritance	GO:0048308	51	0.013
regulation of intracellular signal transduction	GO:1902531	78	0.013
positive regulation of apoptotic process	GO:0043065	3	0.013
nucleoside monophosphate metabolic process	GO:0009123	267	0.013
positive regulation of catalytic activity	GO:0043085	178	0.013
negative regulation of phosphate metabolic process	GO:0045936	49	0.013
covalent chromatin modification	GO:0016569	119	0.013
negative regulation of cellular component organization	GO:0051129	109	0.012
regulation of meiosis i	GO:0060631	14	0.012
regulation of cell communication	GO:0010646	124	0.012
purine containing compound metabolic process	GO:0072521	400	0.012
cellular biogenic amine metabolic process	GO:0006576	37	0.012
ascospore wall assembly	GO:0030476	52	0.012
vesicle organization	GO:0016050	68	0.012
protein localization to membrane	GO:0072657	102	0.012
purine ribonucleotide metabolic process	GO:0009150	372	0.012
nucleocytoplasmic transport	GO:0006913	163	0.012
response to hypoxia	GO:0001666	4	0.012
regulation of cellular amine metabolic process	GO:0033238	21	0.012
regulation of protein serine threonine kinase activity	GO:0071900	41	0.012
regulation of protein kinase activity	GO:0045859	67	0.012
double strand break repair via nonhomologous end joining	GO:0006303	27	0.012
cellular nitrogen compound catabolic process	GO:0044270	494	0.012
cell cycle dna replication	GO:0044786	36	0.012
modification dependent protein catabolic process	GO:0019941	181	0.011
proteolysis	GO:0006508	268	0.011
purine nucleoside metabolic process	GO:0042278	380	0.011
protein folding	GO:0006457	94	0.011
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.011
maintenance of rdna	GO:0043007	9	0.011
phospholipid metabolic process	GO:0006644	125	0.011
positive regulation of phosphorus metabolic process	GO:0010562	147	0.011
positive regulation of rna biosynthetic process	GO:1902680	286	0.011
endomembrane system organization	GO:0010256	74	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.011
cellular amide metabolic process	GO:0043603	59	0.011
cellular lipid metabolic process	GO:0044255	229	0.011
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.011
positive regulation of gene expression	GO:0010628	321	0.011
glycerophospholipid metabolic process	GO:0006650	98	0.011
positive regulation of cellular catabolic process	GO:0031331	128	0.011
carbohydrate catabolic process	GO:0016052	77	0.011
alpha amino acid biosynthetic process	GO:1901607	91	0.011
cellular homeostasis	GO:0019725	138	0.011
regulation of cellular response to stress	GO:0080135	50	0.011
regulation of response to stress	GO:0080134	57	0.011
nucleoside triphosphate catabolic process	GO:0009143	329	0.011
negative regulation of meiotic cell cycle	GO:0051447	24	0.011
regulation of vesicle mediated transport	GO:0060627	39	0.010
nucleoside phosphate catabolic process	GO:1901292	331	0.010
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.010
telomere maintenance via recombination	GO:0000722	32	0.010
oxidation reduction process	GO:0055114	353	0.010
rna splicing	GO:0008380	131	0.010
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.010
mitotic cytokinesis	GO:0000281	58	0.010
regulation of translation	GO:0006417	89	0.010
proteasomal protein catabolic process	GO:0010498	141	0.010
regulation of phosphorylation	GO:0042325	86	0.010
golgi vesicle transport	GO:0048193	188	0.010
regulation of dna templated transcription in response to stress	GO:0043620	51	0.010
modification dependent macromolecule catabolic process	GO:0043632	203	0.010

SPO16 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.014

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