IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

37 known processes

TRK1 (YJL129C)

Trk1p

Entrez: 853312
SGD: S000003665
UniProtKB: P12685

Process Predictions
Disease Predictions

TRK1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cellular cation homeostasis	GO:0030003	100	0.853
cellular ion homeostasis	GO:0006873	112	0.841
potassium ion homeostasis	GO:0055075	7	0.837
ion homeostasis	GO:0050801	118	0.820
cellular potassium ion homeostasis	GO:0030007	6	0.806
cellular chemical homeostasis	GO:0055082	123	0.760
metal ion homeostasis	GO:0055065	79	0.716
cation homeostasis	GO:0055080	105	0.667
monovalent inorganic cation homeostasis	GO:0055067	32	0.579
cellular metal ion homeostasis	GO:0006875	78	0.573
inorganic cation transmembrane transport	GO:0098662	98	0.483
cellular monovalent inorganic cation homeostasis	GO:0030004	27	0.472
homeostatic process	GO:0042592	227	0.456
positive regulation of macromolecule metabolic process	GO:0010604	394	0.450
cellular homeostasis	GO:0019725	138	0.439
chemical homeostasis	GO:0048878	137	0.397
negative regulation of biosynthetic process	GO:0009890	312	0.367
cation transport	GO:0006812	166	0.360
ion transport	GO:0006811	274	0.323
negative regulation of cellular metabolic process	GO:0031324	407	0.319
negative regulation of rna metabolic process	GO:0051253	262	0.298
negative regulation of cellular biosynthetic process	GO:0031327	312	0.287
regulation of biological quality	GO:0065008	391	0.268
negative regulation of gene expression	GO:0010629	312	0.231
transmembrane transport	GO:0055085	349	0.221
negative regulation of macromolecule metabolic process	GO:0010605	375	0.215
metal ion transport	GO:0030001	75	0.211
ion transmembrane transport	GO:0034220	200	0.209
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.180
response to osmotic stress	GO:0006970	83	0.172
cation transmembrane transport	GO:0098655	135	0.163
regulation of cellular component organization	GO:0051128	334	0.154
phosphorylation	GO:0016310	291	0.149
negative regulation of transcription dna templated	GO:0045892	258	0.144
positive regulation of rna biosynthetic process	GO:1902680	286	0.134
establishment of protein localization to organelle	GO:0072594	278	0.132
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.130
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.128
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.126
regulation of mitotic cell cycle	GO:0007346	107	0.126
negative regulation of rna biosynthetic process	GO:1902679	260	0.125
regulation of cellular protein metabolic process	GO:0032268	232	0.120
rna splicing	GO:0008380	131	0.116
multi organism cellular process	GO:0044764	120	0.115
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.113
carboxylic acid transport	GO:0046942	74	0.112
response to organic substance	GO:0010033	182	0.111
organonitrogen compound biosynthetic process	GO:1901566	314	0.103
protein targeting	GO:0006605	272	0.103
monovalent inorganic cation transport	GO:0015672	78	0.101
organic anion transport	GO:0015711	114	0.099
purine containing compound metabolic process	GO:0072521	400	0.095
mrna metabolic process	GO:0016071	269	0.093
chromatin silencing	GO:0006342	147	0.092
multi organism reproductive process	GO:0044703	216	0.091
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.088
regulation of organelle organization	GO:0033043	243	0.087
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.084
positive regulation of rna metabolic process	GO:0051254	294	0.082
anion transport	GO:0006820	145	0.082
response to abiotic stimulus	GO:0009628	159	0.082
positive regulation of transcription dna templated	GO:0045893	286	0.081
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.079
establishment of protein localization	GO:0045184	367	0.078
protein phosphorylation	GO:0006468	197	0.076
positive regulation of cellular component organization	GO:0051130	116	0.075
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.074
positive regulation of cellular biosynthetic process	GO:0031328	336	0.073
mitotic cell cycle process	GO:1903047	294	0.073
cellular response to starvation	GO:0009267	90	0.068
protein localization to organelle	GO:0033365	337	0.065
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.065
nitrogen compound transport	GO:0071705	212	0.064
cellular nitrogen compound catabolic process	GO:0044270	494	0.064
positive regulation of biosynthetic process	GO:0009891	336	0.058
single organism cellular localization	GO:1902580	375	0.058
regulation of cellular component biogenesis	GO:0044087	112	0.057
macromolecule catabolic process	GO:0009057	383	0.057
regulation of cell cycle process	GO:0010564	150	0.054
membrane organization	GO:0061024	276	0.053
organic cyclic compound catabolic process	GO:1901361	499	0.052
cellular response to chemical stimulus	GO:0070887	315	0.051
response to chemical	GO:0042221	390	0.050
single organism catabolic process	GO:0044712	619	0.050
meiotic nuclear division	GO:0007126	163	0.050
carbohydrate derivative metabolic process	GO:1901135	549	0.049
gene silencing	GO:0016458	151	0.049
regulation of dna metabolic process	GO:0051052	100	0.049
ribonucleoside metabolic process	GO:0009119	389	0.047
regulation of protein metabolic process	GO:0051246	237	0.047
regulation of gene silencing	GO:0060968	41	0.046
nucleoside phosphate metabolic process	GO:0006753	458	0.046
cellular response to dna damage stimulus	GO:0006974	287	0.046
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.046
protein localization to vacuole	GO:0072665	92	0.045
regulation of cell communication	GO:0010646	124	0.045
regulation of mitotic cell cycle phase transition	GO:1901990	68	0.045
aromatic compound catabolic process	GO:0019439	491	0.044
chromatin modification	GO:0016568	200	0.044
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.043
organic acid transport	GO:0015849	77	0.043
intracellular protein transport	GO:0006886	319	0.043
establishment of protein localization to vacuole	GO:0072666	91	0.043
organophosphate metabolic process	GO:0019637	597	0.042
regulation of localization	GO:0032879	127	0.042
negative regulation of response to stimulus	GO:0048585	40	0.042
vacuolar transport	GO:0007034	145	0.041
multi organism process	GO:0051704	233	0.040
purine ribonucleoside metabolic process	GO:0046128	380	0.040
sporulation	GO:0043934	132	0.040
ribonucleotide metabolic process	GO:0009259	377	0.039
cell communication	GO:0007154	345	0.039
negative regulation of gene expression epigenetic	GO:0045814	147	0.038
purine ribonucleotide metabolic process	GO:0009150	372	0.037
intracellular signal transduction	GO:0035556	112	0.037
autophagy	GO:0006914	106	0.036
cellular response to extracellular stimulus	GO:0031668	150	0.035
nucleotide metabolic process	GO:0009117	453	0.035
cellular response to abiotic stimulus	GO:0071214	62	0.034
response to nutrient levels	GO:0031667	150	0.034
regulation of response to extracellular stimulus	GO:0032104	20	0.034
dna dependent dna replication	GO:0006261	115	0.034
sexual reproduction	GO:0019953	216	0.033
cellular response to nutrient levels	GO:0031669	144	0.032
positive regulation of gene expression	GO:0010628	321	0.032
single organism signaling	GO:0044700	208	0.031
dna replication	GO:0006260	147	0.031
purine nucleotide metabolic process	GO:0006163	376	0.031
vacuole organization	GO:0007033	75	0.030
negative regulation of protein metabolic process	GO:0051248	85	0.030
nucleobase containing compound catabolic process	GO:0034655	479	0.030
protein transport	GO:0015031	345	0.030
cellular developmental process	GO:0048869	191	0.030
vesicle mediated transport	GO:0016192	335	0.029
nucleobase containing small molecule metabolic process	GO:0055086	491	0.029
cell division	GO:0051301	205	0.029
transcription elongation from rna polymerase ii promoter	GO:0006368	81	0.029
negative regulation of cell communication	GO:0010648	33	0.029
mitochondrion organization	GO:0007005	261	0.029
regulation of transcription from rna polymerase ii promoter in response to stress	GO:0043618	51	0.028
positive regulation of fatty acid beta oxidation by positive regulation of transcription from rna polymerase ii promoter	GO:0097235	1	0.028
sodium ion transport	GO:0006814	9	0.028
regulation of response to stress	GO:0080134	57	0.028
signal transduction	GO:0007165	208	0.028
protein complex biogenesis	GO:0070271	314	0.028
cytokinesis	GO:0000910	92	0.027
nucleoside metabolic process	GO:0009116	394	0.027
heterocycle catabolic process	GO:0046700	494	0.027
negative regulation of cellular component organization	GO:0051129	109	0.027
dna templated transcription elongation	GO:0006354	91	0.027
regulation of phosphorus metabolic process	GO:0051174	230	0.027
regulation of transcription by pheromones	GO:0009373	14	0.027
regulation of catabolic process	GO:0009894	199	0.027
chromatin silencing at silent mating type cassette	GO:0030466	53	0.027
cellular response to external stimulus	GO:0071496	150	0.027
potassium ion transport	GO:0006813	17	0.026
regulation of sodium ion transport	GO:0002028	1	0.026
regulation of cell cycle	GO:0051726	195	0.026
peptidyl amino acid modification	GO:0018193	116	0.026
regulation of chromosome organization	GO:0033044	66	0.026
regulation of cellular carbohydrate metabolic process	GO:0010675	41	0.026
histone modification	GO:0016570	119	0.026
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.026
carbohydrate derivative catabolic process	GO:1901136	339	0.026
response to heat	GO:0009408	69	0.026
regulation of meiotic cell cycle	GO:0051445	43	0.025
nuclear division	GO:0000280	263	0.025
purine nucleoside metabolic process	GO:0042278	380	0.025
positive regulation of phosphate metabolic process	GO:0045937	147	0.025
signaling	GO:0023052	208	0.025
chromatin remodeling	GO:0006338	80	0.025
glycosyl compound metabolic process	GO:1901657	398	0.025
nucleoside catabolic process	GO:0009164	335	0.024
protein dephosphorylation	GO:0006470	40	0.024
regulation of signaling	GO:0023051	119	0.024
cellular response to oxidative stress	GO:0034599	94	0.024
small molecule biosynthetic process	GO:0044283	258	0.024
ribose phosphate metabolic process	GO:0019693	384	0.024
cellular transition metal ion homeostasis	GO:0046916	59	0.024
negative regulation of cellular protein metabolic process	GO:0032269	85	0.023
covalent chromatin modification	GO:0016569	119	0.023
regulation of translation	GO:0006417	89	0.023
cellular response to organic substance	GO:0071310	159	0.023
regulation of dna templated transcription elongation	GO:0032784	44	0.023
chromatin silencing at telomere	GO:0006348	84	0.023
regulation of chromatin silencing	GO:0031935	39	0.023
anatomical structure morphogenesis	GO:0009653	160	0.023
response to pheromone	GO:0019236	92	0.023
positive regulation of sodium ion transport	GO:0010765	1	0.023
regulation of response to stimulus	GO:0048583	157	0.023
cell differentiation	GO:0030154	161	0.023
double strand break repair	GO:0006302	105	0.022
organonitrogen compound catabolic process	GO:1901565	404	0.022
regulation of filamentous growth	GO:0010570	38	0.022
response to external stimulus	GO:0009605	158	0.022
response to extracellular stimulus	GO:0009991	156	0.022
conjugation with cellular fusion	GO:0000747	106	0.022
regulation of gene expression epigenetic	GO:0040029	147	0.022
response to uv	GO:0009411	4	0.022
cell cycle phase transition	GO:0044770	144	0.022
mitotic cell cycle	GO:0000278	306	0.022
response to starvation	GO:0042594	96	0.021
mitotic cytokinesis	GO:0000281	58	0.021
mrna processing	GO:0006397	185	0.021
regulation of signal transduction	GO:0009966	114	0.021
regulation of phosphate metabolic process	GO:0019220	230	0.020
regulation of cellular catabolic process	GO:0031329	195	0.020
macroautophagy	GO:0016236	55	0.020
cellular polysaccharide metabolic process	GO:0044264	55	0.020
cell wall biogenesis	GO:0042546	93	0.020
organic acid biosynthetic process	GO:0016053	152	0.020
protein processing	GO:0016485	64	0.020
chromatin organization	GO:0006325	242	0.020
response to salt stress	GO:0009651	34	0.020
cellular macromolecule catabolic process	GO:0044265	363	0.020
positive regulation of organelle organization	GO:0010638	85	0.020
regulation of cell cycle phase transition	GO:1901987	70	0.020
positive regulation of protein metabolic process	GO:0051247	93	0.020
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.020
lipid biosynthetic process	GO:0008610	170	0.019
mitotic cell cycle checkpoint	GO:0007093	56	0.019
cellular component macromolecule biosynthetic process	GO:0070589	24	0.019
dna repair	GO:0006281	236	0.019
regulation of metal ion transport	GO:0010959	2	0.019
invasive filamentous growth	GO:0036267	65	0.019
maintenance of location	GO:0051235	66	0.019
cell wall macromolecule metabolic process	GO:0044036	27	0.019
filamentous growth	GO:0030447	124	0.019
anatomical structure development	GO:0048856	160	0.019
internal peptidyl lysine acetylation	GO:0018393	52	0.019
single organism developmental process	GO:0044767	258	0.018
regulation of dna dependent dna replication	GO:0090329	37	0.018
cellular lipid metabolic process	GO:0044255	229	0.018
response to organic cyclic compound	GO:0014070	1	0.018
negative regulation of cell cycle process	GO:0010948	86	0.018
regulation of protein modification process	GO:0031399	110	0.018
regulation of nuclear division	GO:0051783	103	0.018
carbohydrate metabolic process	GO:0005975	252	0.018
maintenance of location in cell	GO:0051651	58	0.018
positive regulation of cell cycle	GO:0045787	32	0.018
carbohydrate derivative biosynthetic process	GO:1901137	181	0.018
cellular carbohydrate metabolic process	GO:0044262	135	0.018
regulation of transport	GO:0051049	85	0.018
meiotic cell cycle	GO:0051321	272	0.017
regulation of cellular hyperosmotic salinity response	GO:1900069	2	0.017
ribonucleoprotein complex subunit organization	GO:0071826	152	0.017
regulation of cellular response to stress	GO:0080135	50	0.017
negative regulation of signaling	GO:0023057	30	0.017
cellular lipid catabolic process	GO:0044242	33	0.017
negative regulation of phosphorus metabolic process	GO:0010563	49	0.017
protein targeting to vacuole	GO:0006623	91	0.017
single organism membrane organization	GO:0044802	275	0.017
protein maturation	GO:0051604	76	0.017
oxidation reduction process	GO:0055114	353	0.016
organelle fission	GO:0048285	272	0.016
cell growth	GO:0016049	89	0.016
polysaccharide metabolic process	GO:0005976	60	0.016
conjugation	GO:0000746	107	0.016
mitotic cytokinetic process	GO:1902410	45	0.016
pseudohyphal growth	GO:0007124	75	0.016
cellular polysaccharide biosynthetic process	GO:0033692	38	0.016
single organism carbohydrate metabolic process	GO:0044723	237	0.016
positive regulation of catabolic process	GO:0009896	135	0.016
dephosphorylation	GO:0016311	127	0.016
negative regulation of cell cycle phase transition	GO:1901988	59	0.016
nucleosome organization	GO:0034728	63	0.016
ribonucleoprotein complex assembly	GO:0022618	143	0.016
protein complex assembly	GO:0006461	302	0.016
translation	GO:0006412	230	0.016
regulation of chromatin silencing at telomere	GO:0031938	27	0.016
regulation of sulfite transport	GO:1900071	1	0.016
nucleoside monophosphate metabolic process	GO:0009123	267	0.015
organophosphate biosynthetic process	GO:0090407	182	0.015
organelle localization	GO:0051640	128	0.015
negative regulation of mitotic cell cycle	GO:0045930	63	0.015
protein dna complex assembly	GO:0065004	105	0.015
atp catabolic process	GO:0006200	224	0.015
invasive growth in response to glucose limitation	GO:0001403	61	0.015
cell cycle checkpoint	GO:0000075	82	0.015
regulation of transcription by chromatin organization	GO:0034401	19	0.015
maintenance of protein location in cell	GO:0032507	50	0.015
primary alcohol catabolic process	GO:0034310	1	0.015
positive regulation of cell cycle process	GO:0090068	31	0.015
acetate biosynthetic process	GO:0019413	4	0.015
monocarboxylic acid transport	GO:0015718	24	0.015
nucleoside triphosphate catabolic process	GO:0009143	329	0.015
negative regulation of organelle organization	GO:0010639	103	0.014
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	38	0.014
negative regulation of cellular response to alkaline ph by negative regulation of transcription from rna polymerase ii promoter	GO:1900463	1	0.014
regulation of molecular function	GO:0065009	320	0.014
mitotic nuclear division	GO:0007067	131	0.014
negative regulation of mitotic cell cycle phase transition	GO:1901991	57	0.014
lipid transport	GO:0006869	58	0.014
organic acid metabolic process	GO:0006082	352	0.014
regulation of response to drug	GO:2001023	3	0.014
negative regulation of phosphate metabolic process	GO:0045936	49	0.014
regulation of cell division	GO:0051302	113	0.014
macromolecular complex disassembly	GO:0032984	80	0.014
nuclear transcribed mrna catabolic process	GO:0000956	89	0.013
positive regulation of gene expression epigenetic	GO:0045815	25	0.013
cytokinetic process	GO:0032506	78	0.013
regulation of transcription involved in g1 s transition of mitotic cell cycle	GO:0000083	27	0.013
endocytosis	GO:0006897	90	0.013
trna metabolic process	GO:0006399	151	0.013
negative regulation of cell division	GO:0051782	66	0.013
reproductive process	GO:0022414	248	0.013
positive regulation of molecular function	GO:0044093	185	0.013
organic hydroxy compound biosynthetic process	GO:1901617	81	0.013
posttranscriptional regulation of gene expression	GO:0010608	115	0.013
protein dna complex subunit organization	GO:0071824	153	0.013
protein acetylation	GO:0006473	59	0.013
filamentous growth of a population of unicellular organisms	GO:0044182	109	0.013
transition metal ion homeostasis	GO:0055076	59	0.013
amine metabolic process	GO:0009308	51	0.013
organelle inheritance	GO:0048308	51	0.013
positive regulation of dna templated transcription elongation	GO:0032786	42	0.013
organic hydroxy compound transport	GO:0015850	41	0.013
negative regulation of cell cycle	GO:0045786	91	0.012
cellular response to pheromone	GO:0071444	88	0.012
cellular ketone metabolic process	GO:0042180	63	0.012
positive regulation of cellular protein metabolic process	GO:0032270	89	0.012
organophosphate catabolic process	GO:0046434	338	0.012
membrane fusion	GO:0061025	73	0.012
organelle assembly	GO:0070925	118	0.012
nucleic acid phosphodiester bond hydrolysis	GO:0090305	194	0.012
positive regulation of mitotic cell cycle	GO:0045931	16	0.012
cellular response to osmotic stress	GO:0071470	50	0.012
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.012
cellular glucan metabolic process	GO:0006073	44	0.012
aging	GO:0007568	71	0.012
response to anoxia	GO:0034059	3	0.012
nuclear transport	GO:0051169	165	0.012
cellular response to oxygen containing compound	GO:1901701	43	0.012
negative regulation of chromosome organization	GO:2001251	39	0.012
regulation of cellular ketone metabolic process	GO:0010565	42	0.012
cellular component disassembly	GO:0022411	86	0.012
negative regulation of gene silencing	GO:0060969	27	0.012
positive regulation of growth	GO:0045927	19	0.012
exit from mitosis	GO:0010458	37	0.012
ribonucleoside catabolic process	GO:0042454	332	0.012
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.012
negative regulation of protein modification process	GO:0031400	37	0.012
g1 s transition of mitotic cell cycle	GO:0000082	64	0.012
rna splicing via transesterification reactions	GO:0000375	118	0.012
fungal type cell wall organization or biogenesis	GO:0071852	169	0.012
purine nucleoside catabolic process	GO:0006152	330	0.012
response to ph	GO:0009268	18	0.011
cell cycle dna replication	GO:0044786	36	0.011
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.011
cytoskeleton dependent cytokinesis	GO:0061640	65	0.011
small molecule catabolic process	GO:0044282	88	0.011
developmental process involved in reproduction	GO:0003006	159	0.011
late endosome to vacuole transport	GO:0045324	42	0.011
cell wall organization or biogenesis	GO:0071554	190	0.011
golgi to vacuole transport	GO:0006896	23	0.011
positive regulation of ethanol catabolic process	GO:1900066	1	0.011
single organism membrane fusion	GO:0044801	71	0.011
regulation of response to external stimulus	GO:0032101	20	0.011
aminoglycan biosynthetic process	GO:0006023	15	0.011
hypotonic response	GO:0006971	2	0.011
positive regulation of programmed cell death	GO:0043068	3	0.011
protein complex disassembly	GO:0043241	70	0.011
peptidyl lysine modification	GO:0018205	77	0.011
negative regulation of nuclear division	GO:0051784	62	0.011
dna recombination	GO:0006310	172	0.011
positive regulation of transcription from rna polymerase ii promoter in response to acidic ph	GO:0061402	4	0.011
purine nucleotide biosynthetic process	GO:0006164	41	0.010
negative regulation of meiotic cell cycle	GO:0051447	24	0.010
regulation of nucleotide metabolic process	GO:0006140	110	0.010
cellular response to blue light	GO:0071483	2	0.010
cellular response to uv	GO:0034644	3	0.010
protein deacylation	GO:0035601	27	0.010
regulation of fatty acid oxidation	GO:0046320	3	0.010
positive regulation of lipid catabolic process	GO:0050996	4	0.010
dna damage checkpoint	GO:0000077	29	0.010
positive regulation of transcription from rna polymerase ii promoter by oleic acid	GO:0061429	4	0.010
vacuole fusion	GO:0097576	40	0.010
hexose metabolic process	GO:0019318	78	0.010
positive regulation of cellular response to drug	GO:2001040	3	0.010
nucleoside triphosphate metabolic process	GO:0009141	364	0.010

TRK1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.019

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