| adaptation of signaling pathway | GO:0023058 | 23 | 0.983 | |
| adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion | GO:0000754 | 23 | 0.932 | |
| signal transduction | GO:0007165 | 208 | 0.621 | |
| meiotic nuclear division | GO:0007126 | 163 | 0.438 | Fly |
| intracellular protein transport | GO:0006886 | 319 | 0.401 | Fly |
| establishment of protein localization to organelle | GO:0072594 | 278 | 0.397 | Fly |
| intracellular signal transduction | GO:0035556 | 112 | 0.354 | |
| response to chemical | GO:0042221 | 390 | 0.349 | |
| response to organic substance | GO:0010033 | 182 | 0.326 | |
| cellular response to chemical stimulus | GO:0070887 | 315 | 0.305 | |
| cellular lipid metabolic process | GO:0044255 | 229 | 0.291 | |
| regulation of localization | GO:0032879 | 127 | 0.282 | Rat Fly |
| nuclear transport | GO:0051169 | 165 | 0.264 | Fly |
| nitrogen compound transport | GO:0071705 | 212 | 0.237 | Rat |
| conjugation | GO:0000746 | 107 | 0.227 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 394 | 0.217 | |
| cellular ion homeostasis | GO:0006873 | 112 | 0.213 | |
| regulation of biological quality | GO:0065008 | 391 | 0.198 | |
| establishment of protein localization | GO:0045184 | 367 | 0.197 | Fly |
| cellular chemical homeostasis | GO:0055082 | 123 | 0.191 | |
| establishment of protein localization to vacuole | GO:0072666 | 91 | 0.184 | |
| carboxylic acid metabolic process | GO:0019752 | 338 | 0.184 | |
| protein localization to organelle | GO:0033365 | 337 | 0.181 | Fly |
| regulation of transport | GO:0051049 | 85 | 0.180 | Rat Fly |
| regulation of cellular component organization | GO:0051128 | 334 | 0.158 | |
| protein transport | GO:0015031 | 345 | 0.158 | Fly |
| positive regulation of intracellular protein transport | GO:0090316 | 3 | 0.158 | Fly |
| cellular response to organic substance | GO:0071310 | 159 | 0.158 | |
| signaling | GO:0023052 | 208 | 0.157 | |
| vesicle mediated transport | GO:0016192 | 335 | 0.155 | |
| organophosphate metabolic process | GO:0019637 | 597 | 0.147 | |
| chemical homeostasis | GO:0048878 | 137 | 0.142 | |
| multi organism cellular process | GO:0044764 | 120 | 0.139 | |
| positive regulation of nucleocytoplasmic transport | GO:0046824 | 4 | 0.137 | Fly |
| cellular response to extracellular stimulus | GO:0031668 | 150 | 0.137 | |
| regulation of response to stimulus | GO:0048583 | 157 | 0.136 | |
| reproductive process | GO:0022414 | 248 | 0.129 | |
| regulation of nuclear division | GO:0051783 | 103 | 0.125 | |
| regulation of signaling | GO:0023051 | 119 | 0.125 | |
| ion homeostasis | GO:0050801 | 118 | 0.125 | |
| response to pheromone involved in conjugation with cellular fusion | GO:0000749 | 74 | 0.120 | |
| glycerophospholipid metabolic process | GO:0006650 | 98 | 0.113 | |
| regulation of cell cycle process | GO:0010564 | 150 | 0.112 | |
| single organism signaling | GO:0044700 | 208 | 0.112 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 286 | 0.109 | |
| vacuolar transport | GO:0007034 | 145 | 0.109 | |
| phosphorylation | GO:0016310 | 291 | 0.105 | |
| glycerolipid metabolic process | GO:0046486 | 108 | 0.104 | |
| regulation of cell communication | GO:0010646 | 124 | 0.104 | |
| multi organism reproductive process | GO:0044703 | 216 | 0.100 | |
| cellular homeostasis | GO:0019725 | 138 | 0.099 | |
| growth | GO:0040007 | 157 | 0.098 | |
| cell communication | GO:0007154 | 345 | 0.097 | |
| response to oxidative stress | GO:0006979 | 99 | 0.096 | |
| single organism cellular localization | GO:1902580 | 375 | 0.096 | Fly |
| protein targeting to vacuole | GO:0006623 | 91 | 0.096 | |
| response to external stimulus | GO:0009605 | 158 | 0.092 | |
| cellular response to pheromone | GO:0071444 | 88 | 0.088 | |
| positive regulation of cytoplasmic transport | GO:1903651 | 4 | 0.085 | Fly |
| conjugation with cellular fusion | GO:0000747 | 106 | 0.083 | |
| response to nutrient levels | GO:0031667 | 150 | 0.083 | |
| response to extracellular stimulus | GO:0009991 | 156 | 0.083 | |
| organophosphate biosynthetic process | GO:0090407 | 182 | 0.081 | |
| single organism catabolic process | GO:0044712 | 619 | 0.078 | |
| sexual reproduction | GO:0019953 | 216 | 0.077 | |
| positive regulation of biosynthetic process | GO:0009891 | 336 | 0.076 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 325 | 0.076 | |
| protein targeting to nucleus | GO:0044744 | 57 | 0.074 | Fly |
| organic acid metabolic process | GO:0006082 | 352 | 0.073 | |
| glycosyl compound metabolic process | GO:1901657 | 398 | 0.072 | |
| cellular response to starvation | GO:0009267 | 90 | 0.072 | |
| regulation of intracellular signal transduction | GO:1902531 | 78 | 0.071 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 336 | 0.070 | |
| cellular response to external stimulus | GO:0071496 | 150 | 0.070 | |
| oxoacid metabolic process | GO:0043436 | 351 | 0.069 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 252 | 0.069 | |
| protein complex assembly | GO:0006461 | 302 | 0.069 | |
| cell division | GO:0051301 | 205 | 0.068 | |
| positive regulation of intracellular transport | GO:0032388 | 4 | 0.068 | Fly |
| protein localization to nucleus | GO:0034504 | 74 | 0.067 | Fly |
| cytoskeleton organization | GO:0007010 | 230 | 0.065 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 409 | 0.064 | |
| regulation of anatomical structure size | GO:0090066 | 50 | 0.063 | |
| phospholipid metabolic process | GO:0006644 | 125 | 0.060 | |
| anatomical structure development | GO:0048856 | 160 | 0.059 | Fly |
| regulation of organelle organization | GO:0033043 | 243 | 0.058 | |
| nucleoside phosphate metabolic process | GO:0006753 | 458 | 0.057 | |
| ribonucleoside metabolic process | GO:0009119 | 389 | 0.055 | |
| regulation of cell size | GO:0008361 | 30 | 0.053 | |
| positive regulation of cellular component organization | GO:0051130 | 116 | 0.053 | |
| purine containing compound biosynthetic process | GO:0072522 | 53 | 0.050 | |
| protein complex biogenesis | GO:0070271 | 314 | 0.050 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 314 | 0.050 | |
| ribose phosphate metabolic process | GO:0019693 | 384 | 0.049 | |
| nucleoside monophosphate metabolic process | GO:0009123 | 267 | 0.048 | |
| purine nucleoside monophosphate metabolic process | GO:0009126 | 262 | 0.048 | |
| nucleoside triphosphate biosynthetic process | GO:0009142 | 22 | 0.048 | |
| actin cytoskeleton organization | GO:0030036 | 100 | 0.047 | |
| organelle assembly | GO:0070925 | 118 | 0.047 | |
| positive regulation of apoptotic process | GO:0043065 | 3 | 0.047 | |
| nucleoside metabolic process | GO:0009116 | 394 | 0.046 | |
| cytokinesis | GO:0000910 | 92 | 0.046 | |
| regulation of signal transduction | GO:0009966 | 114 | 0.045 | |
| autophagy | GO:0006914 | 106 | 0.044 | |
| fungal type cell wall organization | GO:0031505 | 145 | 0.044 | Yeast |
| nucleocytoplasmic transport | GO:0006913 | 163 | 0.044 | Fly |
| regulation of intracellular protein transport | GO:0033157 | 13 | 0.043 | Fly |
| response to endogenous stimulus | GO:0009719 | 26 | 0.042 | Rat |
| positive regulation of rna biosynthetic process | GO:1902680 | 286 | 0.042 | |
| homeostatic process | GO:0042592 | 227 | 0.042 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 80 | 0.042 | |
| amide transport | GO:0042886 | 22 | 0.042 | Rat |
| positive regulation of phosphorus metabolic process | GO:0010562 | 147 | 0.041 | |
| response to glucose | GO:0009749 | 13 | 0.041 | Rat |
| positive regulation of phosphate metabolic process | GO:0045937 | 147 | 0.040 | |
| positive regulation of catalytic activity | GO:0043085 | 178 | 0.040 | |
| regulation of meiotic cell cycle | GO:0051445 | 43 | 0.040 | |
| glycosyl compound biosynthetic process | GO:1901659 | 42 | 0.040 | |
| single organism developmental process | GO:0044767 | 258 | 0.039 | Fly |
| lipid metabolic process | GO:0006629 | 269 | 0.039 | |
| cellular response to oxidative stress | GO:0034599 | 94 | 0.039 | |
| developmental process | GO:0032502 | 261 | 0.038 | Fly |
| alcohol metabolic process | GO:0006066 | 112 | 0.038 | |
| ion transport | GO:0006811 | 274 | 0.038 | |
| positive regulation of transport | GO:0051050 | 32 | 0.038 | Rat Fly |
| nucleobase containing small molecule metabolic process | GO:0055086 | 491 | 0.038 | |
| nucleoside monophosphate biosynthetic process | GO:0009124 | 33 | 0.037 | |
| regulation of cellular component size | GO:0032535 | 50 | 0.037 | |
| cellular response to nutrient levels | GO:0031669 | 144 | 0.036 | |
| multi organism process | GO:0051704 | 233 | 0.036 | |
| ribonucleotide metabolic process | GO:0009259 | 377 | 0.035 | |
| actin filament based process | GO:0030029 | 104 | 0.033 | |
| organelle fission | GO:0048285 | 272 | 0.033 | Fly |
| ribose phosphate biosynthetic process | GO:0046390 | 50 | 0.032 | |
| single organism nuclear import | GO:1902593 | 56 | 0.032 | Fly |
| response to drug | GO:0042493 | 41 | 0.032 | Human |
| response to pheromone | GO:0019236 | 92 | 0.031 | |
| ribonucleoside monophosphate metabolic process | GO:0009161 | 265 | 0.031 | |
| cell wall organization or biogenesis | GO:0071554 | 190 | 0.031 | Yeast |
| regulation of phosphate metabolic process | GO:0019220 | 230 | 0.031 | |
| response to oxygen containing compound | GO:1901700 | 61 | 0.029 | Rat |
| actin filament organization | GO:0007015 | 56 | 0.029 | |
| nuclear import | GO:0051170 | 57 | 0.029 | Fly |
| purine containing compound metabolic process | GO:0072521 | 400 | 0.029 | |
| protein localization to vacuole | GO:0072665 | 92 | 0.029 | |
| response to carbohydrate | GO:0009743 | 14 | 0.029 | Rat |
| monocarboxylic acid metabolic process | GO:0032787 | 122 | 0.029 | |
| regulation of protein localization | GO:0032880 | 62 | 0.028 | Fly |
| purine ribonucleoside monophosphate metabolic process | GO:0009167 | 262 | 0.028 | |
| response to metal ion | GO:0010038 | 24 | 0.027 | Human |
| response to starvation | GO:0042594 | 96 | 0.027 | |
| negative regulation of cell cycle | GO:0045786 | 91 | 0.027 | |
| phosphatidylinositol metabolic process | GO:0046488 | 62 | 0.027 | |
| reproduction of a single celled organism | GO:0032505 | 191 | 0.027 | |
| lipid biosynthetic process | GO:0008610 | 170 | 0.027 | |
| positive regulation of signaling | GO:0023056 | 20 | 0.027 | Rat |
| purine nucleoside metabolic process | GO:0042278 | 380 | 0.027 | |
| carbohydrate derivative metabolic process | GO:1901135 | 549 | 0.026 | |
| nuclear division | GO:0000280 | 263 | 0.026 | Fly |
| establishment of organelle localization | GO:0051656 | 96 | 0.026 | |
| cellular macromolecule catabolic process | GO:0044265 | 363 | 0.025 | |
| cellular component disassembly | GO:0022411 | 86 | 0.025 | |
| cellular component movement | GO:0006928 | 20 | 0.024 | |
| positive regulation of phosphorylation | GO:0042327 | 33 | 0.024 | |
| regulation of dna dependent dna replication | GO:0090329 | 37 | 0.024 | |
| regulation of phosphorus metabolic process | GO:0051174 | 230 | 0.024 | |
| regulation of cellular localization | GO:0060341 | 50 | 0.024 | Rat Fly |
| positive regulation of gene expression | GO:0010628 | 321 | 0.024 | |
| nucleoside biosynthetic process | GO:0009163 | 38 | 0.023 | |
| regulation of cell cycle | GO:0051726 | 195 | 0.023 | |
| cellular response to endogenous stimulus | GO:0071495 | 22 | 0.023 | |
| mitotic cell cycle phase transition | GO:0044772 | 141 | 0.023 | |
| purine ribonucleoside metabolic process | GO:0046128 | 380 | 0.023 | |
| positive regulation of programmed cell death | GO:0043068 | 3 | 0.022 | |
| glycerolipid biosynthetic process | GO:0045017 | 71 | 0.022 | |
| positive regulation of protein transport | GO:0051222 | 5 | 0.022 | Fly |
| fatty acid metabolic process | GO:0006631 | 51 | 0.022 | |
| cellular cation homeostasis | GO:0030003 | 100 | 0.022 | |
| cellular response to dna damage stimulus | GO:0006974 | 287 | 0.022 | |
| response to monosaccharide | GO:0034284 | 13 | 0.021 | Rat |
| fungal type cell wall organization or biogenesis | GO:0071852 | 169 | 0.021 | Yeast |
| cellular developmental process | GO:0048869 | 191 | 0.021 | |
| cell morphogenesis | GO:0000902 | 30 | 0.021 | |
| nuclear export | GO:0051168 | 124 | 0.021 | |
| hormone transport | GO:0009914 | 1 | 0.020 | Rat |
| amine metabolic process | GO:0009308 | 51 | 0.020 | |
| protein import into nucleus | GO:0006606 | 55 | 0.020 | Fly |
| negative regulation of cell cycle process | GO:0010948 | 86 | 0.020 | |
| positive regulation of cell death | GO:0010942 | 3 | 0.020 | |
| response to nitrogen compound | GO:1901698 | 18 | 0.020 | Rat |
| cell growth | GO:0016049 | 89 | 0.020 | |
| ribonucleoside triphosphate metabolic process | GO:0009199 | 356 | 0.020 | |
| organic acid biosynthetic process | GO:0016053 | 152 | 0.019 | |
| nucleobase containing compound transport | GO:0015931 | 124 | 0.019 | |
| cellular response to organonitrogen compound | GO:0071417 | 14 | 0.019 | |
| positive regulation of protein localization to nucleus | GO:1900182 | 7 | 0.019 | Fly |
| microtubule based process | GO:0007017 | 117 | 0.019 | |
| glucan biosynthetic process | GO:0009250 | 26 | 0.019 | |
| cellular response to glucose stimulus | GO:0071333 | 8 | 0.019 | Rat |
| positive regulation of response to stimulus | GO:0048584 | 37 | 0.019 | Rat |
| atp metabolic process | GO:0046034 | 251 | 0.017 | |
| glucose metabolic process | GO:0006006 | 65 | 0.017 | |
| response to organonitrogen compound | GO:0010243 | 18 | 0.017 | Rat |
| response to organic cyclic compound | GO:0014070 | 1 | 0.017 | |
| ribonucleoside monophosphate biosynthetic process | GO:0009156 | 31 | 0.017 | |
| anion transport | GO:0006820 | 145 | 0.017 | |
| cation transport | GO:0006812 | 166 | 0.016 | |
| endocytosis | GO:0006897 | 90 | 0.016 | |
| apoptotic process | GO:0006915 | 30 | 0.016 | |
| cell wall organization | GO:0071555 | 146 | 0.016 | Yeast |
| regulation of hormone levels | GO:0010817 | 1 | 0.016 | Rat |
| negative regulation of biosynthetic process | GO:0009890 | 312 | 0.016 | |
| regulation of protein export from nucleus | GO:0046825 | 3 | 0.016 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 364 | 0.016 | |
| negative regulation of meiotic cell cycle | GO:0051447 | 24 | 0.015 | |
| cellular metal ion homeostasis | GO:0006875 | 78 | 0.015 | |
| regulation of protein transport | GO:0051223 | 17 | 0.015 | Fly |
| protein targeting | GO:0006605 | 272 | 0.014 | Fly |
| organic hydroxy compound metabolic process | GO:1901615 | 125 | 0.014 | |
| response to inorganic substance | GO:0010035 | 47 | 0.014 | Human |
| fatty acid biosynthetic process | GO:0006633 | 22 | 0.014 | |
| aromatic compound catabolic process | GO:0019439 | 491 | 0.014 | |
| regulation of molecular function | GO:0065009 | 320 | 0.014 | |
| positive regulation of cell communication | GO:0010647 | 28 | 0.014 | Rat |
| carbohydrate derivative biosynthetic process | GO:1901137 | 181 | 0.014 | |
| cell cycle checkpoint | GO:0000075 | 82 | 0.014 | |
| purine nucleoside biosynthetic process | GO:0042451 | 31 | 0.014 | |
| phosphatidylcholine metabolic process | GO:0046470 | 20 | 0.014 | |
| regulation of dna replication | GO:0006275 | 51 | 0.014 | |
| regulation of intracellular transport | GO:0032386 | 26 | 0.014 | Fly |
| nucleobase containing compound catabolic process | GO:0034655 | 479 | 0.013 | |
| cellular response to oxygen containing compound | GO:1901701 | 43 | 0.013 | Rat |
| positive regulation of secretion | GO:0051047 | 2 | 0.013 | Rat |
| cation homeostasis | GO:0055080 | 105 | 0.013 | |
| positive regulation of secretion by cell | GO:1903532 | 2 | 0.013 | Rat |
| response to topologically incorrect protein | GO:0035966 | 38 | 0.013 | |
| regulation of meiosis | GO:0040020 | 42 | 0.013 | |
| sphingolipid metabolic process | GO:0006665 | 41 | 0.013 | |
| cell budding | GO:0007114 | 48 | 0.013 | |
| positive regulation of protein metabolic process | GO:0051247 | 93 | 0.013 | |
| alpha amino acid catabolic process | GO:1901606 | 28 | 0.013 | |
| ribonucleoprotein complex subunit organization | GO:0071826 | 152 | 0.013 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 42 | 0.013 | |
| dna replication | GO:0006260 | 147 | 0.013 | |
| regulation of transcription factor import into nucleus | GO:0042990 | 4 | 0.013 | Fly |
| organonitrogen compound catabolic process | GO:1901565 | 404 | 0.012 | |
| dna integrity checkpoint | GO:0031570 | 41 | 0.012 | |
| cellular protein complex assembly | GO:0043623 | 209 | 0.012 | |
| lipid transport | GO:0006869 | 58 | 0.012 | |
| cation transmembrane transport | GO:0098655 | 135 | 0.012 | |
| carboxylic acid biosynthetic process | GO:0046394 | 152 | 0.012 | |
| nucleoside catabolic process | GO:0009164 | 335 | 0.012 | |
| regulation of small gtpase mediated signal transduction | GO:0051056 | 47 | 0.012 | |
| trehalose metabolic process | GO:0005991 | 11 | 0.012 | |
| atp catabolic process | GO:0006200 | 224 | 0.012 | |
| organic anion transport | GO:0015711 | 114 | 0.012 | |
| cellular response to topologically incorrect protein | GO:0035967 | 32 | 0.012 | |
| ribonucleoside monophosphate catabolic process | GO:0009158 | 224 | 0.011 | |
| programmed cell death | GO:0012501 | 30 | 0.011 | |
| response to hypoxia | GO:0001666 | 4 | 0.011 | |
| phospholipid biosynthetic process | GO:0008654 | 89 | 0.011 | |
| carboxylic acid transport | GO:0046942 | 74 | 0.011 | |
| cellular amine metabolic process | GO:0044106 | 51 | 0.011 | |
| protein phosphorylation | GO:0006468 | 197 | 0.011 | |
| purine ribonucleotide metabolic process | GO:0009150 | 372 | 0.011 | |
| negative regulation of gene expression | GO:0010629 | 312 | 0.011 | |
| membrane lipid metabolic process | GO:0006643 | 67 | 0.011 | |
| cellular response to hypoxia | GO:0071456 | 4 | 0.011 | |
| organic hydroxy compound biosynthetic process | GO:1901617 | 81 | 0.011 | |
| cellular metabolic compound salvage | GO:0043094 | 20 | 0.011 | |
| heterocycle catabolic process | GO:0046700 | 494 | 0.011 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 115 | 0.011 | |
| positive regulation of signal transduction | GO:0009967 | 20 | 0.011 | |
| positive regulation of intracellular signal transduction | GO:1902533 | 16 | 0.010 | |
| regulation of hydrolase activity | GO:0051336 | 133 | 0.010 | |
| regulation of developmental process | GO:0050793 | 30 | 0.010 | |
| dna damage checkpoint | GO:0000077 | 29 | 0.010 | |
| regulation of cellular catabolic process | GO:0031329 | 195 | 0.010 | |
| response to hexose | GO:0009746 | 13 | 0.010 | Rat |
| sphingolipid biosynthetic process | GO:0030148 | 29 | 0.010 | |
| endomembrane system organization | GO:0010256 | 74 | 0.010 | |
| transition metal ion homeostasis | GO:0055076 | 59 | 0.010 | |
| purine ribonucleotide biosynthetic process | GO:0009152 | 39 | 0.010 | |
| er nucleus signaling pathway | GO:0006984 | 23 | 0.010 | |
| negative regulation of cell cycle phase transition | GO:1901988 | 59 | 0.010 | |
| dephosphorylation | GO:0016311 | 127 | 0.010 | |
| membrane organization | GO:0061024 | 276 | 0.010 | |
| metal ion transport | GO:0030001 | 75 | 0.010 | |
| monocarboxylic acid biosynthetic process | GO:0072330 | 35 | 0.010 | |