IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

62 known processes

SEC2 (YNL272C)

Sec2p

SGD: S000005216
Entrez: 855449
UniProtKB: P17065

Process Predictions
Disease Predictions

SEC2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
cell communication	GO:0007154	345	0.873
golgi to plasma membrane transport	GO:0006893	33	0.831
autophagy	GO:0006914	106	0.823
vesicle mediated transport	GO:0016192	335	0.720
secretion by cell	GO:0032940	50	0.716
macroautophagy	GO:0016236	55	0.715
vesicle organization	GO:0016050	68	0.712
protein targeting	GO:0006605	272	0.643
golgi vesicle transport	GO:0048193	188	0.580
exocytosis	GO:0006887	42	0.565
cellular response to nutrient levels	GO:0031669	144	0.551
response to nutrient levels	GO:0031667	150	0.547
regulation of protein complex assembly	GO:0043254	77	0.547
vesicle docking involved in exocytosis	GO:0006904	8	0.526
intracellular protein transport	GO:0006886	319	0.490
response to extracellular stimulus	GO:0009991	156	0.480
cellular response to external stimulus	GO:0071496	150	0.471
post golgi vesicle mediated transport	GO:0006892	72	0.466
nucleoside phosphate metabolic process	GO:0006753	458	0.435
establishment of protein localization to organelle	GO:0072594	278	0.416
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.383
signaling	GO:0023052	208	0.383
single organism signaling	GO:0044700	208	0.342
er to golgi vesicle mediated transport	GO:0006888	86	0.342
cellular response to starvation	GO:0009267	90	0.338
guanosine containing compound catabolic process	GO:1901069	109	0.324
membrane organization	GO:0061024	276	0.313
positive regulation of cellular component organization	GO:0051130	116	0.312
cellular response to extracellular stimulus	GO:0031668	150	0.303
vacuolar transport	GO:0007034	145	0.302
intracellular signal transduction	GO:0035556	112	0.290
gtp catabolic process	GO:0006184	107	0.284
response to external stimulus	GO:0009605	158	0.275
purine nucleoside triphosphate catabolic process	GO:0009146	329	0.274
protein complex biogenesis	GO:0070271	314	0.273
response to starvation	GO:0042594	96	0.261
single organism catabolic process	GO:0044712	619	0.258
gtp metabolic process	GO:0046039	107	0.233
purine ribonucleoside catabolic process	GO:0046130	330	0.229
establishment of protein localization	GO:0045184	367	0.221
secretion	GO:0046903	50	0.220
organelle assembly	GO:0070925	118	0.208
protein transport	GO:0015031	345	0.206
cellular nitrogen compound catabolic process	GO:0044270	494	0.204
signal transduction	GO:0007165	208	0.197
glycosyl compound catabolic process	GO:1901658	335	0.195
carbohydrate derivative catabolic process	GO:1901136	339	0.193
ribonucleoside triphosphate catabolic process	GO:0009203	327	0.184
vesicle fusion	GO:0006906	33	0.181
organic cyclic compound catabolic process	GO:1901361	499	0.177
cell differentiation	GO:0030154	161	0.168
nucleoside catabolic process	GO:0009164	335	0.168
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.167
cellular protein complex assembly	GO:0043623	209	0.166
protein phosphorylation	GO:0006468	197	0.165
purine ribonucleotide catabolic process	GO:0009154	327	0.160
cytokinetic process	GO:0032506	78	0.159
mitochondrion organization	GO:0007005	261	0.156
glycosyl compound metabolic process	GO:1901657	398	0.155
actin filament based process	GO:0030029	104	0.153
nucleoside metabolic process	GO:0009116	394	0.152
small gtpase mediated signal transduction	GO:0007264	36	0.152
protein complex assembly	GO:0006461	302	0.149
phosphorylation	GO:0016310	291	0.147
purine nucleoside catabolic process	GO:0006152	330	0.146
cytokinesis	GO:0000910	92	0.145
heterocycle catabolic process	GO:0046700	494	0.138
regulation of response to extracellular stimulus	GO:0032104	20	0.132
nucleoside triphosphate metabolic process	GO:0009141	364	0.132
guanosine containing compound metabolic process	GO:1901068	111	0.129
purine containing compound catabolic process	GO:0072523	332	0.126
reproduction of a single celled organism	GO:0032505	191	0.126
purine ribonucleoside triphosphate catabolic process	GO:0009207	327	0.125
nucleotide metabolic process	GO:0009117	453	0.124
regulation of signaling	GO:0023051	119	0.121
membrane docking	GO:0022406	22	0.121
protein import	GO:0017038	122	0.121
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.119
single organism membrane organization	GO:0044802	275	0.118
nucleobase containing compound catabolic process	GO:0034655	479	0.116
establishment of organelle localization	GO:0051656	96	0.113
membrane fusion	GO:0061025	73	0.112
organonitrogen compound catabolic process	GO:1901565	404	0.112
intracellular protein transmembrane transport	GO:0065002	80	0.111
purine containing compound metabolic process	GO:0072521	400	0.111
regulation of cellular component biogenesis	GO:0044087	112	0.111
nucleobase containing small molecule metabolic process	GO:0055086	491	0.110
regulation of cell communication	GO:0010646	124	0.108
ribose phosphate metabolic process	GO:0019693	384	0.104
organophosphate metabolic process	GO:0019637	597	0.104
nucleoside triphosphate catabolic process	GO:0009143	329	0.103
response to chemical	GO:0042221	390	0.102
aromatic compound catabolic process	GO:0019439	491	0.098
anatomical structure development	GO:0048856	160	0.092
positive regulation of exocytosis	GO:0045921	2	0.092
developmental process	GO:0032502	261	0.089
regulation of transport	GO:0051049	85	0.089
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.089
purine nucleotide metabolic process	GO:0006163	376	0.089
ribonucleoside metabolic process	GO:0009119	389	0.087
purine nucleotide catabolic process	GO:0006195	328	0.087
protein localization to membrane	GO:0072657	102	0.084
positive regulation of macromolecule metabolic process	GO:0010604	394	0.083
regulation of response to stress	GO:0080134	57	0.083
protein transmembrane transport	GO:0071806	82	0.082
endosomal transport	GO:0016197	86	0.082
single organism reproductive process	GO:0044702	159	0.081
ribonucleoside catabolic process	GO:0042454	332	0.078
multi organism reproductive process	GO:0044703	216	0.074
purine ribonucleoside metabolic process	GO:0046128	380	0.073
peroxisome organization	GO:0007031	68	0.072
sexual sporulation	GO:0034293	113	0.072
cellular developmental process	GO:0048869	191	0.071
ribonucleotide metabolic process	GO:0009259	377	0.070
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.068
carbohydrate derivative metabolic process	GO:1901135	549	0.067
single organism cellular localization	GO:1902580	375	0.066
purine ribonucleotide metabolic process	GO:0009150	372	0.064
cellular component disassembly	GO:0022411	86	0.063
single organism membrane fusion	GO:0044801	71	0.063
actin cytoskeleton organization	GO:0030036	100	0.062
organelle fusion	GO:0048284	85	0.062
sporulation resulting in formation of a cellular spore	GO:0030435	129	0.061
organophosphate catabolic process	GO:0046434	338	0.060
vesicle docking	GO:0048278	16	0.060
reproductive process	GO:0022414	248	0.059
endomembrane system organization	GO:0010256	74	0.059
cellular component assembly involved in morphogenesis	GO:0010927	73	0.059
intra golgi vesicle mediated transport	GO:0006891	22	0.058
regulation of exocytosis	GO:0017157	5	0.058
nucleotide catabolic process	GO:0009166	330	0.057
regulation of macroautophagy	GO:0016241	15	0.056
cell division	GO:0051301	205	0.055
single organism developmental process	GO:0044767	258	0.055
ncrna processing	GO:0034470	330	0.054
protein targeting to membrane	GO:0006612	52	0.053
ras protein signal transduction	GO:0007265	29	0.053
purine nucleoside metabolic process	GO:0042278	380	0.052
regulation of vesicle mediated transport	GO:0060627	39	0.048
positive regulation of cellular biosynthetic process	GO:0031328	336	0.048
response to organic substance	GO:0010033	182	0.048
regulation of localization	GO:0032879	127	0.048
regulation of cellular localization	GO:0060341	50	0.048
regulation of biological quality	GO:0065008	391	0.047
multi organism process	GO:0051704	233	0.045
regulation of protein metabolic process	GO:0051246	237	0.044
cytoskeleton organization	GO:0007010	230	0.044
organelle inheritance	GO:0048308	51	0.043
regulation of cellular component organization	GO:0051128	334	0.043
positive regulation of secretion by cell	GO:1903532	2	0.042
cellular component morphogenesis	GO:0032989	97	0.042
regulation of autophagy	GO:0010506	18	0.042
establishment of vesicle localization	GO:0051650	9	0.041
regulation of response to stimulus	GO:0048583	157	0.041
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.041
ribonucleotide catabolic process	GO:0009261	327	0.040
positive regulation of cellular component biogenesis	GO:0044089	45	0.040
regulation of cellular catabolic process	GO:0031329	195	0.040
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.040
regulation of cellular protein metabolic process	GO:0032268	232	0.040
cellular response to chemical stimulus	GO:0070887	315	0.039
trna metabolic process	GO:0006399	151	0.039
posttranscriptional regulation of gene expression	GO:0010608	115	0.039
autophagic vacuole assembly	GO:0000045	16	0.039
protein polymerization	GO:0051258	51	0.038
organelle localization	GO:0051640	128	0.038
establishment of protein localization to membrane	GO:0090150	99	0.038
cell development	GO:0048468	107	0.037
exocyst assembly	GO:0001927	4	0.037
regulation of protein phosphorylation	GO:0001932	75	0.037
protein localization to mitochondrion	GO:0070585	63	0.035
sporulation	GO:0043934	132	0.035
trna processing	GO:0008033	101	0.034
transmembrane transport	GO:0055085	349	0.034
regulation of intracellular signal transduction	GO:1902531	78	0.034
anatomical structure morphogenesis	GO:0009653	160	0.034
establishment of protein localization to endoplasmic reticulum	GO:0072599	40	0.033
ascospore formation	GO:0030437	107	0.031
regulation of ras gtpase activity	GO:0032318	41	0.031
positive regulation of protein complex assembly	GO:0031334	39	0.029
positive regulation of transcription dna templated	GO:0045893	286	0.029
homeostatic process	GO:0042592	227	0.029
negative regulation of cellular component organization	GO:0051129	109	0.028
regulation of small gtpase mediated signal transduction	GO:0051056	47	0.028
positive regulation of response to nutrient levels	GO:0032109	12	0.027
early endosome to golgi transport	GO:0034498	11	0.027
regulation of response to external stimulus	GO:0032101	20	0.027
negative regulation of protein complex assembly	GO:0031333	15	0.026
protein targeting to mitochondrion	GO:0006626	56	0.026
sexual reproduction	GO:0019953	216	0.026
response to abiotic stimulus	GO:0009628	159	0.026
peptidyl amino acid modification	GO:0018193	116	0.026
negative regulation of macromolecule metabolic process	GO:0010605	375	0.025
protein localization to plasma membrane	GO:0072659	18	0.025
regulation of catalytic activity	GO:0050790	307	0.025
reproductive process in single celled organism	GO:0022413	145	0.023
rna modification	GO:0009451	99	0.023
cortical actin cytoskeleton organization	GO:0030866	11	0.022
negative regulation of organelle organization	GO:0010639	103	0.022
mitochondrion inheritance	GO:0000001	21	0.022
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.022
regulation of kinase activity	GO:0043549	71	0.022
retrograde transport endosome to golgi	GO:0042147	33	0.022
nucleoside monophosphate metabolic process	GO:0009123	267	0.021
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.021
peptidyl lysine modification	GO:0018205	77	0.021
oxoacid metabolic process	GO:0043436	351	0.021
regulation of catabolic process	GO:0009894	199	0.021
regulation of nucleotide catabolic process	GO:0030811	106	0.021
methylation	GO:0032259	101	0.020
regulation of organelle organization	GO:0033043	243	0.020
mitochondrion localization	GO:0051646	29	0.020
macromolecular complex disassembly	GO:0032984	80	0.020
cell fate commitment	GO:0045165	32	0.020
cellular protein catabolic process	GO:0044257	213	0.020
retrograde vesicle mediated transport golgi to er	GO:0006890	28	0.020
regulation of cellular response to stress	GO:0080135	50	0.019
nitrogen compound transport	GO:0071705	212	0.019
positive regulation of cellular catabolic process	GO:0031331	128	0.019
nucleoside phosphate catabolic process	GO:1901292	331	0.019
ribonucleoprotein complex subunit organization	GO:0071826	152	0.019
protein alkylation	GO:0008213	48	0.019
peroxisomal transport	GO:0043574	22	0.018
positive regulation of kinase activity	GO:0033674	24	0.018
cellular response to organic substance	GO:0071310	159	0.018
protein localization to endoplasmic reticulum	GO:0070972	47	0.018
protein complex disassembly	GO:0043241	70	0.018
positive regulation of gene expression	GO:0010628	321	0.018
positive regulation of transport	GO:0051050	32	0.018
cortical cytoskeleton organization	GO:0030865	11	0.017
regulation of dna metabolic process	GO:0051052	100	0.017
positive regulation of response to external stimulus	GO:0032103	12	0.017
regulation of transferase activity	GO:0051338	83	0.017
establishment of cell polarity	GO:0030010	64	0.017
prenylation	GO:0097354	6	0.017
regulation of gtp catabolic process	GO:0033124	84	0.017
negative regulation of cell cycle process	GO:0010948	86	0.017
cellular macromolecule catabolic process	GO:0044265	363	0.016
positive regulation of protein metabolic process	GO:0051247	93	0.016
ascospore type prospore assembly	GO:0031321	15	0.016
regulation of phosphate metabolic process	GO:0019220	230	0.016
maintenance of protein location	GO:0045185	53	0.016
regulation of protein localization	GO:0032880	62	0.016
macromolecule catabolic process	GO:0009057	383	0.016
ion transport	GO:0006811	274	0.016
positive regulation of cell communication	GO:0010647	28	0.016
regulation of protein kinase activity	GO:0045859	67	0.016
exocyst localization	GO:0051601	6	0.016
dna templated transcription initiation	GO:0006352	71	0.015
developmental process involved in reproduction	GO:0003006	159	0.015
positive regulation of catabolic process	GO:0009896	135	0.015
protein modification by small protein conjugation or removal	GO:0070647	172	0.015
positive regulation of response to stimulus	GO:0048584	37	0.014
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.014
regulation of anatomical structure size	GO:0090066	50	0.014
ribonucleoprotein complex assembly	GO:0022618	143	0.014
asexual reproduction	GO:0019954	48	0.014
regulation of purine nucleotide metabolic process	GO:1900542	109	0.013
response to endogenous stimulus	GO:0009719	26	0.013
negative regulation of protein polymerization	GO:0032272	12	0.013
anion transport	GO:0006820	145	0.013
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.013
g2 m transition of mitotic cell cycle	GO:0000086	38	0.013
positive regulation of organelle organization	GO:0010638	85	0.013
intracellular protein transmembrane import	GO:0044743	67	0.013
negative regulation of gene expression	GO:0010629	312	0.013
mitochondrion distribution	GO:0048311	21	0.013
cellular protein complex disassembly	GO:0043624	42	0.013
endoplasmic reticulum organization	GO:0007029	30	0.013
mrna processing	GO:0006397	185	0.013
rab protein signal transduction	GO:0032482	0	0.012
peroxisome degradation	GO:0030242	22	0.012
cellular lipid metabolic process	GO:0044255	229	0.012
meiotic cell cycle	GO:0051321	272	0.012
regulation of cell cycle g2 m phase transition	GO:1902749	8	0.012
growth	GO:0040007	157	0.012
cellular response to pheromone	GO:0071444	88	0.012
mrna metabolic process	GO:0016071	269	0.012
negative regulation of cellular metabolic process	GO:0031324	407	0.012
regulation of dna replication	GO:0006275	51	0.012
regulation of cell cycle process	GO:0010564	150	0.012
cellular response to endogenous stimulus	GO:0071495	22	0.011
atp catabolic process	GO:0006200	224	0.011
regulation of hydrolase activity	GO:0051336	133	0.011
positive regulation of secretion	GO:0051047	2	0.011
regulation of ras protein signal transduction	GO:0046578	47	0.011
protein localization to organelle	GO:0033365	337	0.011
positive regulation of rna metabolic process	GO:0051254	294	0.011
regulation of protein modification process	GO:0031399	110	0.011
positive regulation of cell death	GO:0010942	3	0.011
regulation of cell cycle	GO:0051726	195	0.011
dephosphorylation	GO:0016311	127	0.011
negative regulation of cellular protein metabolic process	GO:0032269	85	0.011
maintenance of protein location in cell	GO:0032507	50	0.011
monocarboxylic acid metabolic process	GO:0032787	122	0.011
negative regulation of dna metabolic process	GO:0051053	36	0.011
positive regulation of biosynthetic process	GO:0009891	336	0.011
alcohol metabolic process	GO:0006066	112	0.011
response to unfolded protein	GO:0006986	29	0.010
establishment or maintenance of cell polarity	GO:0007163	96	0.010
regulation of response to nutrient levels	GO:0032107	20	0.010

SEC2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org

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