IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

95 known processes

POP2 (YNR052C)

Pop2p

(Aliases: CAF1)

Entrez: 855788
SGD: S000005335
UniProtKB: P39008

Process Predictions
Disease Predictions

POP2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
cellular macromolecule catabolic process	GO:0044265	363	0.999
nuclear transcribed mrna catabolic process deadenylation dependent decay	GO:0000288	44	0.992
macromolecule catabolic process	GO:0009057	383	0.986
mrna catabolic process	GO:0006402	93	0.971
nuclear transcribed mrna catabolic process	GO:0000956	89	0.959
heterocycle catabolic process	GO:0046700	494	0.885
rna catabolic process	GO:0006401	118	0.865
regulation of dna templated transcription elongation	GO:0032784	44	0.832
cellular nitrogen compound catabolic process	GO:0044270	494	0.791
positive regulation of dna templated transcription elongation	GO:0032786	42	0.723
positive regulation of macromolecule metabolic process	GO:0010604	394	0.710
positive regulation of transcription elongation from rna polymerase ii promoter	GO:0032968	38	0.704
dna templated transcription elongation	GO:0006354	91	0.684
mrna metabolic process	GO:0016071	269	0.639
organic cyclic compound catabolic process	GO:1901361	499	0.634
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.560
protein modification by small protein conjugation or removal	GO:0070647	172	0.526
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.501
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.497
positive regulation of rna metabolic process	GO:0051254	294	0.484
positive regulation of cellular biosynthetic process	GO:0031328	336	0.469
aromatic compound catabolic process	GO:0019439	491	0.456
positive regulation of rna biosynthetic process	GO:1902680	286	0.397
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.392
negative regulation of cellular biosynthetic process	GO:0031327	312	0.363
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.358
vesicle mediated transport	GO:0016192	335	0.338	Worm
nucleobase containing compound catabolic process	GO:0034655	479	0.326
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.323
negative regulation of nucleobase containing compound metabolic process	GO:0045934	295	0.306
negative regulation of biosynthetic process	GO:0009890	312	0.273
regulation of transcription elongation from rna polymerase ii promoter	GO:0034243	40	0.272
positive regulation of gene expression	GO:0010628	321	0.270
transcription elongation from rna polymerase ii promoter	GO:0006368	81	0.260
ubiquitin dependent protein catabolic process	GO:0006511	181	0.259
mitotic cell cycle process	GO:1903047	294	0.227
negative regulation of transcription dna templated	GO:0045892	258	0.225
ion transport	GO:0006811	274	0.204
protein modification by small protein conjugation	GO:0032446	144	0.196
positive regulation of biosynthetic process	GO:0009891	336	0.191
cellular homeostasis	GO:0019725	138	0.173
negative regulation of cellular metabolic process	GO:0031324	407	0.171
regulation of cellular protein metabolic process	GO:0032268	232	0.169
mrna processing	GO:0006397	185	0.162
negative regulation of macromolecule metabolic process	GO:0010605	375	0.161
posttranscriptional regulation of gene expression	GO:0010608	115	0.159
endosomal transport	GO:0016197	86	0.148
protein ubiquitination	GO:0016567	118	0.147
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.144
growth	GO:0040007	157	0.143
dna recombination	GO:0006310	172	0.143
vacuolar transport	GO:0007034	145	0.140
single organism cellular localization	GO:1902580	375	0.139
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.134
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.129
response to abiotic stimulus	GO:0009628	159	0.121
cytoskeleton dependent cytokinesis	GO:0061640	65	0.120
negative regulation of rna metabolic process	GO:0051253	262	0.116
organelle assembly	GO:0070925	118	0.106
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.104
replicative cell aging	GO:0001302	46	0.103
positive regulation of organelle organization	GO:0010638	85	0.097
negative regulation of rna biosynthetic process	GO:1902679	260	0.094
homeostatic process	GO:0042592	227	0.094
endocytosis	GO:0006897	90	0.089	Worm
single organism reproductive process	GO:0044702	159	0.085	Worm
regulation of translation	GO:0006417	89	0.084
cell cycle g1 s phase transition	GO:0044843	64	0.084
rna localization	GO:0006403	112	0.080
regulation of cell cycle	GO:0051726	195	0.080	Worm
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.079
multi organism reproductive process	GO:0044703	216	0.075
aging	GO:0007568	71	0.074
mrna 3 end processing	GO:0031124	54	0.073
meiotic cell cycle	GO:0051321	272	0.073	Worm
regulation of biological quality	GO:0065008	391	0.072
dna repair	GO:0006281	236	0.071
chromatin silencing	GO:0006342	147	0.067
nucleic acid phosphodiester bond hydrolysis	GO:0090305	194	0.066
positive regulation of transcription dna templated	GO:0045893	286	0.065
nuclear transcribed mrna poly a tail shortening	GO:0000289	14	0.064
single organism developmental process	GO:0044767	258	0.062	Worm
carbohydrate derivative metabolic process	GO:1901135	549	0.062
negative regulation of gene expression	GO:0010629	312	0.060
response to oxidative stress	GO:0006979	99	0.057
rna 3 end processing	GO:0031123	88	0.057
positive regulation of cell cycle	GO:0045787	32	0.056	Worm
regulation of protein metabolic process	GO:0051246	237	0.055
regulation of cellular catabolic process	GO:0031329	195	0.054
cell aging	GO:0007569	70	0.052
translation	GO:0006412	230	0.050
negative regulation of gene expression epigenetic	GO:0045814	147	0.049
gene silencing	GO:0016458	151	0.048
cellular lipid metabolic process	GO:0044255	229	0.048
negative regulation of chromatin silencing	GO:0031936	25	0.048
dna replication	GO:0006260	147	0.046
g1 s transition of mitotic cell cycle	GO:0000082	64	0.042
regulation of dna replication	GO:0006275	51	0.041
regulation of cell cycle process	GO:0010564	150	0.040
oxidation reduction process	GO:0055114	353	0.039
regulation of organelle organization	GO:0033043	243	0.038
response to chemical	GO:0042221	390	0.038
positive regulation of molecular function	GO:0044093	185	0.037
cellular response to heat	GO:0034605	53	0.034
intracellular protein transport	GO:0006886	319	0.033
sexual reproduction	GO:0019953	216	0.033
organelle fission	GO:0048285	272	0.032
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.032
chemical homeostasis	GO:0048878	137	0.031
cation transport	GO:0006812	166	0.030
single organism signaling	GO:0044700	208	0.029
cellular lipid catabolic process	GO:0044242	33	0.029
multi organism process	GO:0051704	233	0.028
double strand break repair	GO:0006302	105	0.027
double strand break repair via homologous recombination	GO:0000724	54	0.027
cellular response to organic substance	GO:0071310	159	0.027
mitotic cell cycle	GO:0000278	306	0.027	Worm
anatomical structure homeostasis	GO:0060249	74	0.026
negative regulation of dna metabolic process	GO:0051053	36	0.026
lipid localization	GO:0010876	60	0.026
cell communication	GO:0007154	345	0.025
protein transport	GO:0015031	345	0.025
negative regulation of dna replication	GO:0008156	15	0.024
regulation of gene silencing	GO:0060968	41	0.023
regulation of response to stimulus	GO:0048583	157	0.023
lipid metabolic process	GO:0006629	269	0.023
meiotic cell cycle process	GO:1903046	229	0.022
reproductive process	GO:0022414	248	0.022	Worm
positive regulation of catabolic process	GO:0009896	135	0.022
chromatin modification	GO:0016568	200	0.022
cellular chemical homeostasis	GO:0055082	123	0.021
cellular response to chemical stimulus	GO:0070887	315	0.021
meiotic nuclear division	GO:0007126	163	0.021
proteasomal protein catabolic process	GO:0010498	141	0.020
dna dependent dna replication	GO:0006261	115	0.020
establishment of protein localization	GO:0045184	367	0.020
modification dependent macromolecule catabolic process	GO:0043632	203	0.020
response to osmotic stress	GO:0006970	83	0.020
golgi vesicle transport	GO:0048193	188	0.020
protein localization to organelle	GO:0033365	337	0.020
establishment or maintenance of cell polarity	GO:0007163	96	0.019
organonitrogen compound biosynthetic process	GO:1901566	314	0.019
positive regulation of cell cycle process	GO:0090068	31	0.019
carbohydrate biosynthetic process	GO:0016051	82	0.019
mitochondrion localization	GO:0051646	29	0.019
cell wall organization or biogenesis	GO:0071554	190	0.019
negative regulation of gene silencing	GO:0060969	27	0.019
negative regulation of response to stimulus	GO:0048585	40	0.018
cellular component disassembly	GO:0022411	86	0.018
regulation of mrna metabolic process	GO:1903311	17	0.018
mitotic cytokinesis	GO:0000281	58	0.018
cellular protein catabolic process	GO:0044257	213	0.018
dna integrity checkpoint	GO:0031570	41	0.018
nucleosome organization	GO:0034728	63	0.018
mitochondrial genome maintenance	GO:0000002	40	0.018
membrane organization	GO:0061024	276	0.018
regulation of dna dependent dna replication	GO:0090329	37	0.018
regulation of chromatin silencing	GO:0031935	39	0.018
regulation of catabolic process	GO:0009894	199	0.018
sporulation	GO:0043934	132	0.017
single organism catabolic process	GO:0044712	619	0.017
monovalent inorganic cation transport	GO:0015672	78	0.017
cellular response to nutrient	GO:0031670	50	0.016
protein monoubiquitination	GO:0006513	13	0.016
response to organic substance	GO:0010033	182	0.016
regulation of gene expression epigenetic	GO:0040029	147	0.016
filamentous growth	GO:0030447	124	0.016
carbohydrate derivative biosynthetic process	GO:1901137	181	0.016
regulation of dna metabolic process	GO:0051052	100	0.016
reproduction of a single celled organism	GO:0032505	191	0.015
developmental process involved in reproduction	GO:0003006	159	0.015	Worm
regulation of localization	GO:0032879	127	0.015
cellular developmental process	GO:0048869	191	0.015
translational initiation	GO:0006413	56	0.015
protein catabolic process	GO:0030163	221	0.015
dna dependent dna replication maintenance of fidelity	GO:0045005	14	0.014
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.014
cellular response to dna damage stimulus	GO:0006974	287	0.014
anatomical structure development	GO:0048856	160	0.014	Worm
mitotic cytokinetic process	GO:1902410	45	0.014
chromatin remodeling	GO:0006338	80	0.013
positive regulation of protein metabolic process	GO:0051247	93	0.013
filamentous growth of a population of unicellular organisms	GO:0044182	109	0.013
chromatin organization	GO:0006325	242	0.013
nuclear transcribed mrna catabolic process exonucleolytic	GO:0000291	12	0.013
cytokinesis	GO:0000910	92	0.013
growth of unicellular organism as a thread of attached cells	GO:0070783	105	0.013
ribonucleoprotein complex assembly	GO:0022618	143	0.012
cell division	GO:0051301	205	0.012
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.012
regulation of cellular component organization	GO:0051128	334	0.012
dna templated transcription termination	GO:0006353	42	0.012
regulation of dna recombination	GO:0000018	24	0.012
organophosphate biosynthetic process	GO:0090407	182	0.012
ribonucleoprotein complex subunit organization	GO:0071826	152	0.012
response to external stimulus	GO:0009605	158	0.011
negative regulation of carbohydrate metabolic process	GO:0045912	17	0.011
small molecule biosynthetic process	GO:0044283	258	0.011
regulation of meiotic cell cycle	GO:0051445	43	0.011	Worm
pseudohyphal growth	GO:0007124	75	0.011
purine nucleotide metabolic process	GO:0006163	376	0.010
response to uv	GO:0009411	4	0.010
rna phosphodiester bond hydrolysis exonucleolytic	GO:0090503	29	0.010
sexual sporulation	GO:0034293	113	0.010

POP2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.025

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