| cofactor metabolic process | GO:0051186 | 126 | 0.898 | Rat |
| coenzyme metabolic process | GO:0006732 | 104 | 0.858 | Rat |
| oxidoreduction coenzyme metabolic process | GO:0006733 | 58 | 0.843 | Rat |
| carboxylic acid metabolic process | GO:0019752 | 338 | 0.787 | |
| oxidation reduction process | GO:0055114 | 353 | 0.767 | |
| generation of precursor metabolites and energy | GO:0006091 | 147 | 0.706 | Rat |
| energy derivation by oxidation of organic compounds | GO:0015980 | 125 | 0.649 | Rat |
| organic acid metabolic process | GO:0006082 | 352 | 0.603 | |
| aerobic respiration | GO:0009060 | 55 | 0.603 | Rat |
| small molecule biosynthetic process | GO:0044283 | 258 | 0.583 | Yeast |
| oxoacid metabolic process | GO:0043436 | 351 | 0.561 | |
| cellular respiration | GO:0045333 | 82 | 0.442 | Rat |
| organophosphate metabolic process | GO:0019637 | 597 | 0.440 | Rat |
| nucleobase containing small molecule metabolic process | GO:0055086 | 491 | 0.423 | Rat |
| nucleoside phosphate metabolic process | GO:0006753 | 458 | 0.418 | Rat |
| pyridine containing compound metabolic process | GO:0072524 | 53 | 0.412 | Rat |
| pyridine nucleotide metabolic process | GO:0019362 | 45 | 0.328 | Rat |
| tricarboxylic acid metabolic process | GO:0072350 | 3 | 0.303 | |
| nicotinamide nucleotide metabolic process | GO:0046496 | 44 | 0.280 | Rat |
| nucleotide metabolic process | GO:0009117 | 453 | 0.189 | Rat |
| monocarboxylic acid metabolic process | GO:0032787 | 122 | 0.157 | Yeast |
| carbohydrate metabolic process | GO:0005975 | 252 | 0.147 | Yeast |
| cellular response to chemical stimulus | GO:0070887 | 315 | 0.141 | |
| single organism catabolic process | GO:0044712 | 619 | 0.127 | |
| tricarboxylic acid cycle | GO:0006099 | 6 | 0.107 | Rat |
| protein maturation | GO:0051604 | 76 | 0.099 | |
| single organism developmental process | GO:0044767 | 258 | 0.089 | |
| protein processing | GO:0016485 | 64 | 0.085 | |
| multi organism process | GO:0051704 | 233 | 0.083 | |
| organonitrogen compound catabolic process | GO:1901565 | 404 | 0.077 | |
| organonitrogen compound biosynthetic process | GO:1901566 | 314 | 0.070 | Yeast |
| dicarboxylic acid metabolic process | GO:0043648 | 20 | 0.069 | Rat |
| pyruvate metabolic process | GO:0006090 | 37 | 0.068 | |
| growth | GO:0040007 | 157 | 0.066 | |
| regulation of organelle organization | GO:0033043 | 243 | 0.066 | |
| cofactor biosynthetic process | GO:0051188 | 80 | 0.065 | |
| lipid metabolic process | GO:0006629 | 269 | 0.063 | |
| aging | GO:0007568 | 71 | 0.063 | |
| mitochondrial translation | GO:0032543 | 52 | 0.056 | |
| response to chemical | GO:0042221 | 390 | 0.055 | |
| carboxylic acid biosynthetic process | GO:0046394 | 152 | 0.055 | Yeast |
| ribonucleoside metabolic process | GO:0009119 | 389 | 0.054 | |
| glucose metabolic process | GO:0006006 | 65 | 0.054 | |
| cellular amine metabolic process | GO:0044106 | 51 | 0.052 | |
| translation | GO:0006412 | 230 | 0.048 | |
| apoptotic process | GO:0006915 | 30 | 0.047 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 394 | 0.047 | |
| nucleoside triphosphate metabolic process | GO:0009141 | 364 | 0.046 | |
| aromatic compound catabolic process | GO:0019439 | 491 | 0.045 | |
| positive regulation of cellular component organization | GO:0051130 | 116 | 0.045 | |
| response to abiotic stimulus | GO:0009628 | 159 | 0.044 | |
| cell aging | GO:0007569 | 70 | 0.044 | |
| cellular amino acid metabolic process | GO:0006520 | 225 | 0.043 | Yeast |
| cell death | GO:0008219 | 30 | 0.042 | |
| nad metabolic process | GO:0019674 | 25 | 0.042 | Rat |
| glycosyl compound metabolic process | GO:1901657 | 398 | 0.041 | |
| mitochondrion organization | GO:0007005 | 261 | 0.039 | |
| developmental process | GO:0032502 | 261 | 0.039 | |
| regulation of cellular component organization | GO:0051128 | 334 | 0.039 | |
| positive regulation of apoptotic process | GO:0043065 | 3 | 0.037 | |
| regulation of molecular function | GO:0065009 | 320 | 0.037 | |
| coenzyme biosynthetic process | GO:0009108 | 66 | 0.036 | |
| regulation of biological quality | GO:0065008 | 391 | 0.035 | |
| programmed cell death | GO:0012501 | 30 | 0.035 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 409 | 0.035 | |
| purine ribonucleoside metabolic process | GO:0046128 | 380 | 0.033 | |
| amine metabolic process | GO:0009308 | 51 | 0.032 | |
| regulation of protein metabolic process | GO:0051246 | 237 | 0.032 | |
| organic hydroxy compound metabolic process | GO:1901615 | 125 | 0.031 | |
| alcohol metabolic process | GO:0006066 | 112 | 0.030 | |
| regulation of response to stimulus | GO:0048583 | 157 | 0.028 | |
| phosphorylation | GO:0016310 | 291 | 0.028 | |
| purine nucleotide metabolic process | GO:0006163 | 376 | 0.028 | |
| nucleoside phosphate biosynthetic process | GO:1901293 | 80 | 0.027 | |
| transition metal ion homeostasis | GO:0055076 | 59 | 0.026 | |
| protein localization to organelle | GO:0033365 | 337 | 0.026 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 336 | 0.025 | |
| carbohydrate derivative metabolic process | GO:1901135 | 549 | 0.024 | |
| organic acid biosynthetic process | GO:0016053 | 152 | 0.024 | Yeast |
| nadh metabolic process | GO:0006734 | 12 | 0.024 | Rat |
| carbohydrate derivative biosynthetic process | GO:1901137 | 181 | 0.024 | |
| response to organic cyclic compound | GO:0014070 | 1 | 0.022 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 89 | 0.021 | |
| protein transport | GO:0015031 | 345 | 0.021 | |
| maintenance of location | GO:0051235 | 66 | 0.021 | |
| cellular amino acid biosynthetic process | GO:0008652 | 118 | 0.021 | Yeast |
| heterocycle catabolic process | GO:0046700 | 494 | 0.020 | |
| endocytosis | GO:0006897 | 90 | 0.019 | |
| cellular macromolecule catabolic process | GO:0044265 | 363 | 0.019 | |
| response to organic substance | GO:0010033 | 182 | 0.019 | |
| monocarboxylic acid biosynthetic process | GO:0072330 | 35 | 0.019 | |
| negative regulation of organelle organization | GO:0010639 | 103 | 0.018 | |
| reproductive process in single celled organism | GO:0022413 | 145 | 0.018 | |
| positive regulation of gene expression | GO:0010628 | 321 | 0.018 | |
| regulation of phosphorylation | GO:0042325 | 86 | 0.018 | |
| ribose phosphate metabolic process | GO:0019693 | 384 | 0.018 | |
| positive regulation of cell death | GO:0010942 | 3 | 0.018 | |
| response to oxidative stress | GO:0006979 | 99 | 0.017 | |
| sexual reproduction | GO:0019953 | 216 | 0.017 | |
| cellular developmental process | GO:0048869 | 191 | 0.017 | |
| regulation of growth | GO:0040008 | 50 | 0.016 | |
| macromolecule catabolic process | GO:0009057 | 383 | 0.016 | |
| positive regulation of organelle organization | GO:0010638 | 85 | 0.016 | |
| regulation of localization | GO:0032879 | 127 | 0.015 | |
| regulation of transferase activity | GO:0051338 | 83 | 0.014 | |
| death | GO:0016265 | 30 | 0.014 | |
| cellular lipid metabolic process | GO:0044255 | 229 | 0.014 | |
| nucleoside metabolic process | GO:0009116 | 394 | 0.014 | |
| positive regulation of catalytic activity | GO:0043085 | 178 | 0.013 | |
| cellular nitrogen compound catabolic process | GO:0044270 | 494 | 0.013 | |
| regulation of phosphate metabolic process | GO:0019220 | 230 | 0.013 | |
| organic cyclic compound catabolic process | GO:1901361 | 499 | 0.013 | |
| response to external stimulus | GO:0009605 | 158 | 0.013 | |
| dna replication | GO:0006260 | 147 | 0.013 | |
| cell differentiation | GO:0030154 | 161 | 0.013 | |
| positive regulation of protein metabolic process | GO:0051247 | 93 | 0.013 | |
| anatomical structure development | GO:0048856 | 160 | 0.012 | |
| single organism signaling | GO:0044700 | 208 | 0.012 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 412 | 0.012 | |
| carbohydrate catabolic process | GO:0016052 | 77 | 0.012 | |
| ribonucleotide metabolic process | GO:0009259 | 377 | 0.012 | |
| regulation of mitochondrion organization | GO:0010821 | 20 | 0.012 | |
| fungal type cell wall organization | GO:0031505 | 145 | 0.011 | |
| purine ribonucleotide metabolic process | GO:0009150 | 372 | 0.011 | |
| replicative cell aging | GO:0001302 | 46 | 0.011 | |
| multi organism reproductive process | GO:0044703 | 216 | 0.011 | |
| purine containing compound metabolic process | GO:0072521 | 400 | 0.011 | |
| signal transduction | GO:0007165 | 208 | 0.011 | |
| regulation of phosphorus metabolic process | GO:0051174 | 230 | 0.011 | |
| regulation of translation | GO:0006417 | 89 | 0.011 | |
| regulation of signal transduction | GO:0009966 | 114 | 0.011 | |
| positive regulation of programmed cell death | GO:0043068 | 3 | 0.011 | |
| positive regulation of molecular function | GO:0044093 | 185 | 0.010 | |
| regulation of chromosome organization | GO:0033044 | 66 | 0.010 | |
| positive regulation of biosynthetic process | GO:0009891 | 336 | 0.010 | |
| nucleobase containing compound catabolic process | GO:0034655 | 479 | 0.010 | |
