IMP: Integrative Multi-species Prediction

Saccharomyces cerevisiae

33 known processes

HEM15 (YOR176W)

Hem15p

Entrez: 854347
SGD: S000005702
UniProtKB: P16622

Process Predictions
Disease Predictions

HEM15 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
energy derivation by oxidation of organic compounds	GO:0015980	125	0.261
organophosphate biosynthetic process	GO:0090407	182	0.230
oxidation reduction process	GO:0055114	353	0.229
cofactor metabolic process	GO:0051186	126	0.219
organophosphate metabolic process	GO:0019637	597	0.205
carbohydrate derivative biosynthetic process	GO:1901137	181	0.197
carbohydrate derivative metabolic process	GO:1901135	549	0.188
generation of precursor metabolites and energy	GO:0006091	147	0.169
nucleobase containing small molecule metabolic process	GO:0055086	491	0.151
glycerophospholipid metabolic process	GO:0006650	98	0.115
glycosylation	GO:0070085	66	0.112
nucleotide biosynthetic process	GO:0009165	79	0.110
nucleoside phosphate metabolic process	GO:0006753	458	0.108
cofactor biosynthetic process	GO:0051188	80	0.102
cellular lipid metabolic process	GO:0044255	229	0.095
coenzyme metabolic process	GO:0006732	104	0.094
glycerolipid metabolic process	GO:0046486	108	0.090
positive regulation of cellular biosynthetic process	GO:0031328	336	0.088
coenzyme biosynthetic process	GO:0009108	66	0.088
protein glycosylation	GO:0006486	57	0.086
aerobic respiration	GO:0009060	55	0.086
pyridine nucleotide metabolic process	GO:0019362	45	0.082
positive regulation of macromolecule metabolic process	GO:0010604	394	0.080
nucleotide metabolic process	GO:0009117	453	0.074
nucleoside triphosphate metabolic process	GO:0009141	364	0.073
glycogen metabolic process	GO:0005977	30	0.070
glycosyl compound biosynthetic process	GO:1901659	42	0.069
single organism carbohydrate metabolic process	GO:0044723	237	0.064
carbohydrate metabolic process	GO:0005975	252	0.063
nucleoside phosphate biosynthetic process	GO:1901293	80	0.062
regulation of transcription from rna polymerase ii promoter	GO:0006357	394	0.062
regulation of biological quality	GO:0065008	391	0.062
monocarboxylic acid metabolic process	GO:0032787	122	0.061
positive regulation of macromolecule biosynthetic process	GO:0010557	325	0.061
phospholipid biosynthetic process	GO:0008654	89	0.061
positive regulation of biosynthetic process	GO:0009891	336	0.061
lipid metabolic process	GO:0006629	269	0.059
nicotinamide nucleotide metabolic process	GO:0046496	44	0.058
nitrogen compound transport	GO:0071705	212	0.056
purine nucleoside metabolic process	GO:0042278	380	0.055
sexual reproduction	GO:0019953	216	0.055
cellular developmental process	GO:0048869	191	0.054
cell development	GO:0048468	107	0.053
positive regulation of gene expression	GO:0010628	321	0.052
cellular protein catabolic process	GO:0044257	213	0.052
positive regulation of nucleic acid templated transcription	GO:1903508	286	0.051
ribose phosphate metabolic process	GO:0019693	384	0.051
nucleoside metabolic process	GO:0009116	394	0.050
reproductive process in single celled organism	GO:0022413	145	0.050
single organism developmental process	GO:0044767	258	0.049
cellular carbohydrate metabolic process	GO:0044262	135	0.048
energy reserve metabolic process	GO:0006112	32	0.048
purine containing compound metabolic process	GO:0072521	400	0.048
cellular respiration	GO:0045333	82	0.048
nucleoside biosynthetic process	GO:0009163	38	0.047
negative regulation of cellular biosynthetic process	GO:0031327	312	0.047
cytoskeleton organization	GO:0007010	230	0.047
phospholipid metabolic process	GO:0006644	125	0.046
cell differentiation	GO:0030154	161	0.045
regulation of cell cycle process	GO:0010564	150	0.044
glucan metabolic process	GO:0044042	44	0.044
reproductive process	GO:0022414	248	0.044
glycosyl compound metabolic process	GO:1901657	398	0.042
cellular response to chemical stimulus	GO:0070887	315	0.042
purine containing compound biosynthetic process	GO:0072522	53	0.042
developmental process	GO:0032502	261	0.041
phosphorylation	GO:0016310	291	0.040
positive regulation of nucleobase containing compound metabolic process	GO:0045935	409	0.039
purine ribonucleotide metabolic process	GO:0009150	372	0.039
ribosome biogenesis	GO:0042254	335	0.039
cellular macromolecule catabolic process	GO:0044265	363	0.038
oxidoreduction coenzyme metabolic process	GO:0006733	58	0.038
macromolecule catabolic process	GO:0009057	383	0.038
purine nucleoside monophosphate biosynthetic process	GO:0009127	28	0.037
negative regulation of biosynthetic process	GO:0009890	312	0.037
nad metabolic process	GO:0019674	25	0.037
single organism catabolic process	GO:0044712	619	0.036
developmental process involved in reproduction	GO:0003006	159	0.036
sexual sporulation	GO:0034293	113	0.036
protein localization to organelle	GO:0033365	337	0.035
negative regulation of organelle organization	GO:0010639	103	0.035
glycoprotein metabolic process	GO:0009100	62	0.035
actin filament based process	GO:0030029	104	0.034
purine ribonucleoside biosynthetic process	GO:0046129	31	0.034
reproduction of a single celled organism	GO:0032505	191	0.034
negative regulation of macromolecule biosynthetic process	GO:0010558	291	0.033
actin cytoskeleton organization	GO:0030036	100	0.033
anatomical structure formation involved in morphogenesis	GO:0048646	136	0.033
cellular component assembly involved in morphogenesis	GO:0010927	73	0.033
homeostatic process	GO:0042592	227	0.032
positive regulation of rna biosynthetic process	GO:1902680	286	0.032
ion homeostasis	GO:0050801	118	0.032
sexual sporulation resulting in formation of a cellular spore	GO:0043935	113	0.031
hexose metabolic process	GO:0019318	78	0.031
ascospore formation	GO:0030437	107	0.031
ribose phosphate biosynthetic process	GO:0046390	50	0.031
detection of carbohydrate stimulus	GO:0009730	3	0.030
regulation of organelle organization	GO:0033043	243	0.030
response to abiotic stimulus	GO:0009628	159	0.030
multi organism process	GO:0051704	233	0.030
purine nucleoside triphosphate biosynthetic process	GO:0009145	17	0.029
cellular component morphogenesis	GO:0032989	97	0.029
anatomical structure morphogenesis	GO:0009653	160	0.028
regulation of phosphate metabolic process	GO:0019220	230	0.028
organelle assembly	GO:0070925	118	0.028
meiotic cell cycle process	GO:1903046	229	0.028
purine ribonucleoside monophosphate metabolic process	GO:0009167	262	0.028
nucleoside monophosphate biosynthetic process	GO:0009124	33	0.027
organelle localization	GO:0051640	128	0.027
positive regulation of transcription dna templated	GO:0045893	286	0.027
nucleoside monophosphate metabolic process	GO:0009123	267	0.027
cellular response to abiotic stimulus	GO:0071214	62	0.027
cell division	GO:0051301	205	0.027
glucan biosynthetic process	GO:0009250	26	0.027
positive regulation of nitrogen compound metabolic process	GO:0051173	412	0.026
mitochondrion organization	GO:0007005	261	0.026
anatomical structure development	GO:0048856	160	0.026
multi organism reproductive process	GO:0044703	216	0.026
detection of stimulus	GO:0051606	4	0.026
carbohydrate biosynthetic process	GO:0016051	82	0.026
pyridine containing compound biosynthetic process	GO:0072525	24	0.026
cell communication	GO:0007154	345	0.025
detection of glucose	GO:0051594	3	0.025
negative regulation of cell division	GO:0051782	66	0.025
ribonucleotide biosynthetic process	GO:0009260	44	0.025
ribonucleoside monophosphate metabolic process	GO:0009161	265	0.025
macromolecule glycosylation	GO:0043413	57	0.025
dna dependent dna replication	GO:0006261	115	0.024
single organism reproductive process	GO:0044702	159	0.024
cellular homeostasis	GO:0019725	138	0.024
cellular ion homeostasis	GO:0006873	112	0.024
single organism signaling	GO:0044700	208	0.024
single organism membrane organization	GO:0044802	275	0.024
cellular response to osmotic stress	GO:0071470	50	0.024
ion transport	GO:0006811	274	0.023
nucleobase containing compound catabolic process	GO:0034655	479	0.023
nucleus organization	GO:0006997	62	0.023
polysaccharide biosynthetic process	GO:0000271	39	0.023
ribonucleotide metabolic process	GO:0009259	377	0.023
regulation of carbohydrate biosynthetic process	GO:0043255	31	0.023
oxoacid metabolic process	GO:0043436	351	0.022
meiotic cell cycle	GO:0051321	272	0.022
ncrna processing	GO:0034470	330	0.022
lipid biosynthetic process	GO:0008610	170	0.022
regulation of nuclear division	GO:0051783	103	0.022
gene silencing	GO:0016458	151	0.022
organic acid metabolic process	GO:0006082	352	0.022
nuclear transport	GO:0051169	165	0.022
membrane organization	GO:0061024	276	0.022
cellular response to organic substance	GO:0071310	159	0.022
purine nucleoside triphosphate metabolic process	GO:0009144	356	0.022
response to organic substance	GO:0010033	182	0.021
purine ribonucleoside triphosphate biosynthetic process	GO:0009206	17	0.021
organonitrogen compound catabolic process	GO:1901565	404	0.021
ribonucleoside biosynthetic process	GO:0042455	37	0.021
nucleocytoplasmic transport	GO:0006913	163	0.021
regulation of signaling	GO:0023051	119	0.021
chemical homeostasis	GO:0048878	137	0.021
protein complex biogenesis	GO:0070271	314	0.020
purine nucleotide metabolic process	GO:0006163	376	0.020
anion transport	GO:0006820	145	0.020
monosaccharide metabolic process	GO:0005996	83	0.020
carboxylic acid metabolic process	GO:0019752	338	0.020
single organism carbohydrate catabolic process	GO:0044724	73	0.020
glycogen biosynthetic process	GO:0005978	17	0.020
cellular cation homeostasis	GO:0030003	100	0.020
regulation of cell division	GO:0051302	113	0.020
cell wall organization	GO:0071555	146	0.020
negative regulation of cellular component organization	GO:0051129	109	0.020
cellular polysaccharide metabolic process	GO:0044264	55	0.020
positive regulation of secretion	GO:0051047	2	0.019
polysaccharide metabolic process	GO:0005976	60	0.019
pyridine containing compound metabolic process	GO:0072524	53	0.019
glycerophospholipid biosynthetic process	GO:0046474	68	0.019
rna localization	GO:0006403	112	0.019
rrna metabolic process	GO:0016072	244	0.018
response to organic cyclic compound	GO:0014070	1	0.018
regulation of signal transduction	GO:0009966	114	0.018
ribonucleoside triphosphate metabolic process	GO:0009199	356	0.018
cellular ketone metabolic process	GO:0042180	63	0.018
maintenance of protein location in cell	GO:0032507	50	0.018
establishment or maintenance of cell polarity	GO:0007163	96	0.018
regulation of cytoskeleton organization	GO:0051493	63	0.018
cellular chemical homeostasis	GO:0055082	123	0.018
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	252	0.018
regulation of glycogen biosynthetic process	GO:0005979	9	0.018
trehalose metabolic process	GO:0005991	11	0.017
disaccharide biosynthetic process	GO:0046351	7	0.017
dna replication	GO:0006260	147	0.017
disaccharide metabolic process	GO:0005984	25	0.017
response to chemical	GO:0042221	390	0.017
oligosaccharide metabolic process	GO:0009311	35	0.017
cellular carbohydrate biosynthetic process	GO:0034637	49	0.017
protein transport	GO:0015031	345	0.017
regulation of carbohydrate metabolic process	GO:0006109	43	0.017
metal ion homeostasis	GO:0055065	79	0.017
proteolysis involved in cellular protein catabolic process	GO:0051603	198	0.017
regulation of cell cycle	GO:0051726	195	0.017
negative regulation of cell cycle	GO:0045786	91	0.017
cellular glucan metabolic process	GO:0006073	44	0.017
detection of hexose stimulus	GO:0009732	3	0.017
signal transduction	GO:0007165	208	0.017
peptidyl amino acid modification	GO:0018193	116	0.017
dna replication initiation	GO:0006270	48	0.016
negative regulation of cellular metabolic process	GO:0031324	407	0.016
regulation of gene expression epigenetic	GO:0040029	147	0.016
response to osmotic stress	GO:0006970	83	0.016
regulation of protein polymerization	GO:0032271	33	0.016
regulation of cellular component organization	GO:0051128	334	0.016
protein complex assembly	GO:0006461	302	0.016
regulation of cellular ketone metabolic process	GO:0010565	42	0.016
maintenance of location in cell	GO:0051651	58	0.015
hormone transport	GO:0009914	1	0.015
chromatin silencing	GO:0006342	147	0.015
purine ribonucleoside metabolic process	GO:0046128	380	0.015
purine ribonucleotide biosynthetic process	GO:0009152	39	0.015
chromatin silencing at silent mating type cassette	GO:0030466	53	0.015
cellular amide metabolic process	GO:0043603	59	0.015
signaling	GO:0023052	208	0.015
regulation of anatomical structure size	GO:0090066	50	0.015
purine nucleoside biosynthetic process	GO:0042451	31	0.015
sporulation	GO:0043934	132	0.015
nadph regeneration	GO:0006740	13	0.015
regulation of protein metabolic process	GO:0051246	237	0.015
positive regulation of rna metabolic process	GO:0051254	294	0.015
regulation of phosphorus metabolic process	GO:0051174	230	0.014
monosaccharide biosynthetic process	GO:0046364	31	0.014
chromatin silencing at telomere	GO:0006348	84	0.014
fungal type cell wall organization	GO:0031505	145	0.014
protein folding	GO:0006457	94	0.014
conjugation with cellular fusion	GO:0000747	106	0.014
establishment of protein localization	GO:0045184	367	0.014
organelle fission	GO:0048285	272	0.014
budding cell bud growth	GO:0007117	29	0.014
cell budding	GO:0007114	48	0.014
positive regulation of cell communication	GO:0010647	28	0.014
regulation of cell communication	GO:0010646	124	0.014
glycoprotein biosynthetic process	GO:0009101	61	0.014
detection of chemical stimulus	GO:0009593	3	0.014
trehalose biosynthetic process	GO:0005992	7	0.014
regulation of localization	GO:0032879	127	0.014
response to pheromone involved in conjugation with cellular fusion	GO:0000749	74	0.014
nucleic acid transport	GO:0050657	94	0.014
nucleobase containing compound transport	GO:0015931	124	0.013
purine nucleoside monophosphate metabolic process	GO:0009126	262	0.013
protein polymerization	GO:0051258	51	0.013
protein processing	GO:0016485	64	0.013
nuclear import	GO:0051170	57	0.013
cellular transition metal ion homeostasis	GO:0046916	59	0.013
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	137	0.013
cellular protein complex assembly	GO:0043623	209	0.013
cellular nitrogen compound catabolic process	GO:0044270	494	0.013
conjugation	GO:0000746	107	0.013
cell morphogenesis	GO:0000902	30	0.013
aromatic compound catabolic process	GO:0019439	491	0.013
protein n linked glycosylation	GO:0006487	34	0.013
phosphatidylinositol metabolic process	GO:0046488	62	0.013
positive regulation of cytoskeleton organization	GO:0051495	39	0.013
positive regulation of catabolic process	GO:0009896	135	0.013
regulation of cellular component biogenesis	GO:0044087	112	0.013
cell cycle checkpoint	GO:0000075	82	0.013
glycosyl compound catabolic process	GO:1901658	335	0.013
regulation of translation	GO:0006417	89	0.013
transition metal ion homeostasis	GO:0055076	59	0.013
cellular response to oxidative stress	GO:0034599	94	0.013
atp biosynthetic process	GO:0006754	17	0.012
establishment of protein localization to organelle	GO:0072594	278	0.012
meiotic nuclear division	GO:0007126	163	0.012
negative regulation of nucleic acid templated transcription	GO:1903507	260	0.012
negative regulation of nitrogen compound metabolic process	GO:0051172	300	0.012
nuclear export	GO:0051168	124	0.012
filamentous growth	GO:0030447	124	0.012
ketone biosynthetic process	GO:0042181	13	0.012
positive regulation of programmed cell death	GO:0043068	3	0.012
positive regulation of organelle organization	GO:0010638	85	0.012
maintenance of location	GO:0051235	66	0.012
negative regulation of rna metabolic process	GO:0051253	262	0.012
endosomal transport	GO:0016197	86	0.012
negative regulation of gene expression epigenetic	GO:0045814	147	0.012
positive regulation of cellular component organization	GO:0051130	116	0.012
rrna processing	GO:0006364	227	0.012
ribonucleoside metabolic process	GO:0009119	389	0.012
asexual reproduction	GO:0019954	48	0.012
regulation of protein depolymerization	GO:1901879	12	0.012
maintenance of protein location	GO:0045185	53	0.012
ribonucleoside catabolic process	GO:0042454	332	0.012
regulation of catabolic process	GO:0009894	199	0.012
positive regulation of carbohydrate metabolic process	GO:0045913	13	0.012
meiotic chromosome segregation	GO:0045132	31	0.011
organic hydroxy compound transport	GO:0015850	41	0.011
positive regulation of protein complex assembly	GO:0031334	39	0.011
peptide metabolic process	GO:0006518	28	0.011
response to glucose	GO:0009749	13	0.011
regulation of generation of precursor metabolites and energy	GO:0043467	23	0.011
dna repair	GO:0006281	236	0.011
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	289	0.011
regulation of response to stimulus	GO:0048583	157	0.011
adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion	GO:0000754	23	0.011
quinone metabolic process	GO:1901661	13	0.011
lipid modification	GO:0030258	37	0.011
intracellular protein transport	GO:0006886	319	0.011
negative regulation of gene expression	GO:0010629	312	0.011
cellular metal ion homeostasis	GO:0006875	78	0.011
amine metabolic process	GO:0009308	51	0.011
cellular response to anoxia	GO:0071454	3	0.011
positive regulation of intracellular protein transport	GO:0090316	3	0.011
hexose catabolic process	GO:0019320	24	0.011
chromosome segregation	GO:0007059	159	0.011
rna transport	GO:0050658	92	0.011
regulation of hormone levels	GO:0010817	1	0.011
purine ribonucleoside triphosphate metabolic process	GO:0009205	354	0.011
purine nucleoside catabolic process	GO:0006152	330	0.010
monosaccharide catabolic process	GO:0046365	28	0.010
positive regulation of cell death	GO:0010942	3	0.010
cellular lipid catabolic process	GO:0044242	33	0.010
cation homeostasis	GO:0055080	105	0.010
carbohydrate derivative catabolic process	GO:1901136	339	0.010
negative regulation of macromolecule metabolic process	GO:0010605	375	0.010
regulation of gluconeogenesis	GO:0006111	16	0.010
organelle inheritance	GO:0048308	51	0.010
regulation of chromatin silencing at telomere	GO:0031938	27	0.010
glucose metabolic process	GO:0006006	65	0.010
positive regulation of cellular component biogenesis	GO:0044089	45	0.010

HEM15 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in yeast and predicted with the yeast functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.022
disease of metabolism	DOID:0014667	0.011
inherited metabolic disorder	DOID:655	0.011

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