Danio rerio

34 known processes

ap1m2

adaptor-related protein complex 1, mu 2 subunit

(Aliases: Ap1m1,MGC103537,zgc:103537)

ap1m2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of cellular processGO:00485222010.352
regulation of biological qualityGO:00650082630.225
response to drugGO:004249330.169
hormone transportGO:000991420.154
agingGO:000756820.143
hormone secretionGO:004687920.109
regulation of hormone secretionGO:004688320.108
negative regulation of biological processGO:00485193040.103
positive regulation of cellular component biogenesisGO:004408930.102
regulation of metabolic processGO:00192223590.100
response to external stimulusGO:00096052640.100
locomotionGO:00400113130.095
Worm
positive regulation of cellular catabolic processGO:003133130.085
regulation of cell communicationGO:00106462320.083
multicellular organismal homeostasisGO:0048871290.082
transportGO:00068102200.078
regulation of autophagyGO:001050630.078
establishment of localizationGO:00512342440.077
regulation of response to stimulusGO:00485832690.077
cellular macromolecule metabolic processGO:00442603910.074
regulation of multicellular organism growthGO:004001440.073
regulation of response to nutrient levelsGO:003210710.072
organonitrogen compound metabolic processGO:1901564740.069
cellular response to nutrient levelsGO:003166920.069
guanosine containing compound metabolic processGO:190106840.068
small molecule metabolic processGO:0044281770.064
nucleoside monophosphate catabolic processGO:000912540.064
regulation of cellular carbohydrate metabolic processGO:001067540.063
regulation of developmental processGO:00507932470.063
regulation of carbohydrate metabolic processGO:000610940.062
type b pancreatic cell developmentGO:000332340.062
regulation of primary metabolic processGO:00800903110.062
organic acid metabolic processGO:0006082310.062
guanosine containing compound catabolic processGO:190106920.062
carbohydrate derivative metabolic processGO:1901135610.060
cellular aromatic compound metabolic processGO:00067252950.058
positive regulation of transportGO:005105020.057
cellular nitrogen compound metabolic processGO:00346412900.057
autophagyGO:000691440.057
peptide transportGO:001583310.057
monovalent inorganic cation transportGO:0015672420.056
single organism transportGO:00447652060.054
cell motilityGO:00488702440.053
organic cyclic compound biosynthetic processGO:19013622230.053
atp catabolic processGO:000620040.053
phagocytosisGO:000690930.053
single organism metabolic processGO:00447102170.052
cellular carbohydrate metabolic processGO:004426240.052
negative regulation of cellular processGO:00485232830.052
oxoacid metabolic processGO:0043436310.051
nucleoside phosphate metabolic processGO:0006753280.051
killing of cells in other organism involved in symbiotic interactionGO:005188310.050
nitrogen compound metabolic processGO:00068073190.050
nucleobase containing compound metabolic processGO:00061392740.049
xenobiotic metabolic processGO:000680540.049
regulation of purine nucleotide catabolic processGO:003312120.049
nucleic acid templated transcriptionGO:00976591810.049
macroautophagyGO:001623610.047
gtp metabolic processGO:004603940.047
regulation of multicellular organismal developmentGO:20000262230.047
regulation of biosynthetic processGO:00098892500.047
response to chemicalGO:00422213200.046
single organism localizationGO:19025782250.046
regulation of metal ion transportGO:001095940.046
signal transductionGO:00071654550.045
homeostatic processGO:00425921420.044
chordate embryonic developmentGO:00430092710.044
columnar cuboidal epithelial cell differentiationGO:0002065380.043
cellular component morphogenesisGO:00329893360.042
Worm
regulation of molecular functionGO:0065009700.042
aromatic compound biosynthetic processGO:00194382170.041
transmembrane transportGO:00550851200.041
response to nutrientGO:000758430.041
cellular biosynthetic processGO:00442492860.041
regulation of gtp catabolic processGO:003312420.041
larval developmentGO:000216420.041
Worm
organic cyclic compound metabolic processGO:19013603010.040
lipid storageGO:001991510.040
negative regulation of kinase activityGO:003367340.040
regulation of nucleotide catabolic processGO:003081120.039
mitochondrion organizationGO:000700540.039
gene expressionGO:00104672520.038
cellular macromolecule biosynthetic processGO:00346452240.038
response to other organismGO:0051707970.038
positive regulation of gtpase activityGO:004354710.037
regulation of protein localization to nucleusGO:190018020.037
negative regulation of nucleocytoplasmic transportGO:004682320.036
regulation of cellular metabolic processGO:00313233200.036
regulation of nucleobase containing compound metabolic processGO:00192192500.036
positive regulation of nucleoside metabolic processGO:004597910.036
regulation of nucleoside metabolic processGO:000911820.035
response to external biotic stimulusGO:0043207970.035
cellular protein metabolic processGO:00442671290.035
regulation of catalytic activityGO:0050790550.035
cell morphogenesisGO:00009022890.035
Worm
regulation of response to oxidative stressGO:190288220.035
programmed cell deathGO:00125011190.034
macromolecule modificationGO:00434121110.034
regulation of multicellular organismal processGO:00512392770.034
phosphorus metabolic processGO:00067931090.034
carboxylic acid metabolic processGO:0019752220.034
water homeostasisGO:003010440.034
macromolecule biosynthetic processGO:00090592270.032
positive regulation of developmental processGO:0051094500.032
regulation of nitrogen compound metabolic processGO:00511712510.032
positive regulation of purine nucleotide catabolic processGO:003312310.031
intracellular signal transductionGO:0035556850.031
regulation of phosphate metabolic processGO:0019220430.031
negative regulation of protein kinase activityGO:000646940.031
cellular amino acid metabolic processGO:000652070.031
regulation of rna biosynthetic processGO:20011412130.031
cellular ketone metabolic processGO:0042180110.031
glucose homeostasisGO:004259310.031
nucleobase containing compound biosynthetic processGO:00346542050.031
positive regulation of nucleotide catabolic processGO:003081310.031
cell matrix adhesionGO:000716040.031
response to biotic stimulusGO:0009607970.031
regulation of response to extracellular stimulusGO:003210410.030
organic substance biosynthetic processGO:19015762890.030
cellular response to starvationGO:000926710.030
regulation of extrinsic apoptotic signaling pathwayGO:200123630.030
purine nucleoside monophosphate catabolic processGO:000912840.030
negative regulation of programmed cell deathGO:0043069580.030
regulation of membrane potentialGO:0042391230.029
regulation of synapse assemblyGO:005196330.029
protein modification processGO:00362111000.029
digestive tract developmentGO:00485652650.029
cellular response to extracellular stimulusGO:003166820.029
negative regulation of hormone secretionGO:004688820.028
hematopoietic or lymphoid organ developmentGO:00485341910.028
cell substrate adhesionGO:003158940.028
regulation of organ growthGO:004662030.027
negative regulation of protein phosphorylationGO:000193340.027
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.027
purine ribonucleoside metabolic processGO:0046128100.027
cellular response to chemical stimulusGO:00708871570.027
cellular nitrogen compound biosynthetic processGO:00442712180.026
hemopoiesisGO:00300971830.026
regulation of signal transductionGO:00099662250.026
neurological system processGO:0050877620.026
ribonucleoside monophosphate catabolic processGO:000915840.026
phosphorylationGO:0016310690.026
oxidation reduction processGO:0055114410.026
cellular localizationGO:0051641970.026
brain developmentGO:00074202930.026
regulation of transportGO:0051049450.026
heterocycle biosynthetic processGO:00181302150.025
protein polyubiquitinationGO:000020940.025
heterocycle metabolic processGO:00464832900.025
gastrulationGO:00073692080.025
negative regulation of extrinsic apoptotic signaling pathwayGO:200123720.025
cell migrationGO:00164772370.024
cation transmembrane transportGO:0098655650.024
regulation of cytokine productionGO:000181730.024
biosynthetic processGO:00090582940.024
protein metabolic processGO:00195381830.024
cell projection organizationGO:00300302840.023
Worm
gtp catabolic processGO:000618420.023
positive regulation of cytoskeleton organizationGO:005149530.023
negative regulation of catalytic activityGO:0043086210.023
cellular component movementGO:00069283350.023
regulation of cellular ketone metabolic processGO:001056570.023
protein localization to nucleusGO:003450430.022
purine ribonucleoside monophosphate catabolic processGO:000916940.022
positive regulation of secretionGO:005104710.022
regulation of protein complex assemblyGO:004325430.022
regulation of cell deathGO:00109411030.022
regulation of cell substrate adhesionGO:001081010.022
regulation of transcription dna templatedGO:00063552130.022
nucleic acid metabolic processGO:00903042440.022
ion transmembrane transportGO:0034220910.022
response to temperature stimulusGO:0009266150.022
negative regulation of macromolecule metabolic processGO:0010605760.022
positive regulation of catabolic processGO:000989640.022
lipid oxidationGO:003444010.022
regulation of cell developmentGO:00602841000.021
response to uvGO:000941130.021
cell projection morphogenesisGO:00488582440.021
Worm
regulation of anatomical structure morphogenesisGO:00226031300.021
regulation of hormone levelsGO:0010817210.020
liver developmentGO:0001889960.020
cellular modified amino acid metabolic processGO:000657530.020
negative regulation of multicellular organismal processGO:0051241690.020
cell deathGO:00082191210.020
regulation of oxidative stress induced cell deathGO:190320120.020
fat soluble vitamin metabolic processGO:000677540.020
regulation of macromolecule metabolic processGO:00602553170.020
positive regulation of cellular carbohydrate metabolic processGO:001067610.019
embryo development ending in birth or egg hatchingGO:00097922710.019
Worm
deathGO:00162651210.019
cellular protein modification processGO:00064641000.019
endoplasmic reticulum unfolded protein responseGO:003096820.019
regulation of cellular amine metabolic processGO:003323800.019
negative regulation of cell deathGO:0060548600.019
regulation of dendrite developmentGO:005077330.019
morphogenesis of an epitheliumGO:00020093330.019
system processGO:00030081850.019
rna metabolic processGO:00160702190.018
positive regulation of multicellular organismal processGO:0051240520.018
membrane fusionGO:006102520.018
lipid homeostasisGO:005508830.018
glucocorticoid metabolic processGO:000821120.018
immune system processGO:00023762410.018
Worm
regulation of blood pressureGO:000821710.018
regulation of localizationGO:00328791040.018
growthGO:00400071740.018
negative regulation of protein import into nucleusGO:004230820.018
cellular response to hypoxiaGO:007145610.018
peptidyl serine phosphorylationGO:001810510.018
regulation of cellular response to oxidative stressGO:190040720.018
extrinsic apoptotic signaling pathway via death domain receptorsGO:000862510.018
ion transportGO:00068111140.018
negative regulation of secretion by cellGO:190353120.018
regulation of signalingGO:00230512350.018
swimming behaviorGO:003626980.017
maintenance of locationGO:005123540.017
disruption of cells of other organismGO:004436410.017
regulation of protein catabolic processGO:004217610.017
cellular response to external stimulusGO:007149620.017
actin filament based processGO:0030029640.017
regulation of cell matrix adhesionGO:000195210.017
sensory organ developmentGO:00074233930.017
peptide metabolic processGO:000651810.017
positive regulation of protein complex assemblyGO:003133420.017
immune system developmentGO:00025201910.017
regulation of sodium ion transportGO:000202820.017
nucleobase containing small molecule metabolic processGO:0055086320.016
regulation of peptidyl tyrosine phosphorylationGO:005073010.016
intrinsic apoptotic signaling pathway in response to oxidative stressGO:000863120.016
positive regulation of catalytic activityGO:0043085250.016
multicellular organism growthGO:003526440.016
hydrogen peroxide metabolic processGO:004274320.016
positive regulation of biological processGO:00485182530.016
negative regulation of cellular metabolic processGO:0031324770.016
cell killingGO:000190620.016
regulation of cellular component organizationGO:0051128860.016
regulation of gene expressionGO:00104682650.016
negative regulation of dna replicationGO:000815620.016
regulation of gtpase activityGO:004308720.016
cellular respirationGO:004533330.016
nucleotide metabolic processGO:0009117280.015
protein import into nucleusGO:000660630.015
regulation of endocrine processGO:004406020.015
cell projection assemblyGO:0030031640.015
Worm
monocyte differentiationGO:003022420.015
cellular response to radiationGO:007147840.015
amide transportGO:0042886120.015
organic substance transportGO:0071702580.015
Worm
regulation of apoptotic processGO:0042981980.015
nuclear exportGO:005116810.015
adult behaviorGO:003053420.015
killing of cells of other organismGO:003164010.015
negative regulation of cellular biosynthetic processGO:0031327550.015
cellular response to oxygen levelsGO:007145310.015
regulation of rna metabolic processGO:00512522240.015
zymogen activationGO:003163830.015
regulation of response to external stimulusGO:0032101310.015
regulation of cellular amino acid metabolic processGO:000652100.015
negative regulation of rna metabolic processGO:0051253480.015
adherens junction organizationGO:003433240.015
long chain fatty acid metabolic processGO:000167610.015
negative regulation of protein localization to nucleusGO:190018120.014
negative regulation of nitrogen compound metabolic processGO:0051172590.014
negative regulation of cytoplasmic transportGO:190365020.014
embryonic hemopoiesisGO:0035162530.014
protein localization to plasma membraneGO:007265910.014
negative regulation of molecular functionGO:0044092230.014
gland developmentGO:00487321430.014
cellular response to stressGO:0033554620.014
regulation of heart growthGO:006042020.014
nitrogen compound transportGO:0071705230.014
positive regulation of gtp catabolic processGO:003312610.014
positive regulation of epithelial cell differentiationGO:003085820.014
regulation of oxidative stress induced intrinsic apoptotic signaling pathwayGO:190217520.014
regulation of dendrite morphogenesisGO:004881430.014
heart contractionGO:0060047710.014
positive regulation of macromolecule metabolic processGO:0010604930.014
cellular protein catabolic processGO:004425740.014
regulation of striated muscle contractionGO:000694220.014
energy reserve metabolic processGO:000611220.014
regulation of cytoplasmic transportGO:190364940.014
cellular amine metabolic processGO:004410620.014
regulation of neurogenesisGO:0050767870.014
positive regulation of signalingGO:0023056560.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178680.014
negative regulation of stem cell differentiationGO:200073720.013
cell cell signalingGO:0007267520.013
regulation of transporter activityGO:003240920.013
regulation of synapse organizationGO:005080730.013
response to glucoseGO:000974930.013
regulation of cellular biosynthetic processGO:00313262450.013
myeloid cell differentiationGO:0030099860.013
apoptotic process involved in developmentGO:190274220.013
response to ketoneGO:190165410.013
regulation of cellular macromolecule biosynthetic processGO:20001122220.013
vitamin biosynthetic processGO:000911020.013
regulation of phosphorus metabolic processGO:0051174430.013
regulation of neuron differentiationGO:0045664560.013
steroid hormone secretionGO:003592910.013
negative regulation of signalingGO:0023057960.013
response to inorganic substanceGO:0010035380.013
enteroendocrine cell differentiationGO:003588390.013
cellular catabolic processGO:0044248270.013
regulation of circadian rhythmGO:004275240.013
amine metabolic processGO:000930820.013
cellular response to unfolded proteinGO:003462020.013
positive regulation of cell developmentGO:0010720250.013
transcription dna templatedGO:00063511810.013
response to stressGO:00069502630.013
Worm
negative regulation of cellular macromolecule biosynthetic processGO:2000113480.013
regulation of steroid hormone secretionGO:200083110.013
negative regulation of rna biosynthetic processGO:1902679450.013
positive regulation of small gtpase mediated signal transductionGO:005105710.013
cellular response to decreased oxygen levelsGO:003629410.012
generation of neuronsGO:00486993850.012
regulation of protein bindingGO:004339330.012
endosome organizationGO:000703220.012
developmental growth involved in morphogenesisGO:0060560860.012
multicellular organismal signalingGO:0035637220.012
regulation of protein import into nucleusGO:004230620.012
carbohydrate homeostasisGO:003350010.012
regulation of protein transportGO:005122330.012
organophosphate metabolic processGO:0019637370.012
nucleocytoplasmic transportGO:000691340.012
regulation of tube sizeGO:003515020.012
regulation of postsynaptic membrane potentialGO:006007810.012
negative regulation of intracellular protein transportGO:009031730.012
phosphate containing compound metabolic processGO:00067961080.012
cell death in response to oxidative stressGO:003647320.012
inorganic ion transmembrane transportGO:0098660570.012
purine nucleotide metabolic processGO:0006163270.012
apoptotic process involved in morphogenesisGO:006056120.012
neuron differentiationGO:00301823530.012
membrane invaginationGO:001032410.012
cell part morphogenesisGO:00329902460.012
Worm
positive regulation of secretion by cellGO:190353210.012
triglyceride homeostasisGO:007032820.012
response to carbohydrateGO:000974330.012
regulation of cellular component movementGO:0051270550.012
cell surface receptor signaling pathwayGO:00071663250.012
sensory system developmentGO:0048880760.012
hepaticobiliary system developmentGO:0061008980.011
negative regulation of cell communicationGO:0010648960.011
cellular response to topologically incorrect proteinGO:003596720.011
regulation of growth rateGO:004000910.011
regulation of dna replicationGO:000627530.011
positive regulation of carbohydrate metabolic processGO:004591310.011
er nucleus signaling pathwayGO:000698420.011
ribose phosphate metabolic processGO:0019693270.011
organelle assemblyGO:00709251100.011
Worm
positive regulation of cellular amine metabolic processGO:003324000.011
negative regulation of mapk cascadeGO:004340940.011
inorganic cation transmembrane transportGO:0098662500.011
protein dephosphorylationGO:000647030.011
transmission of nerve impulseGO:0019226190.011
endocrine hormone secretionGO:006098620.011
purine ribonucleotide metabolic processGO:0009150270.011
nuclear importGO:005117030.011
internal protein amino acid acetylationGO:000647520.011
regulation of cardiac muscle contractionGO:005511720.011
positive regulation of cell adhesionGO:004578510.011
myelin assemblyGO:003228810.011
fat soluble vitamin biosynthetic processGO:004236220.011
protein acetylationGO:000647320.011
proteolysis involved in cellular protein catabolic processGO:005160330.011
cellular amide metabolic processGO:004360340.011
apoptotic processGO:00069151160.011
modification dependent macromolecule catabolic processGO:004363230.011
positive regulation of map kinase activityGO:004340630.011
regulation of cell killingGO:003134120.011
regulation of response to biotic stimulusGO:000283120.011
negative regulation of biosynthetic processGO:0009890550.011
regulation of bindingGO:005109830.010
neural tube patterningGO:0021532330.010
multi organism processGO:00517041340.010
establishment of protein localization to plasma membraneGO:009000210.010
negative regulation of metabolic processGO:0009892860.010
regulation of proteolysis involved in cellular protein catabolic processGO:190305010.010
regulation of ion transmembrane transporter activityGO:003241220.010
nuclear transportGO:005116940.010
cellular component biogenesisGO:00440851780.010
Worm
peptidyl lysine dimethylationGO:001802710.010
phototransductionGO:000760220.010
muscle fiber developmentGO:0048747520.010
positive regulation of cell activationGO:005086710.010
type b pancreatic cell differentiationGO:000330980.010
negative regulation of intracellular transportGO:003238730.010
positive regulation of cellular metabolic processGO:0031325940.010
negative regulation of protein serine threonine kinase activityGO:007190120.010

ap1m2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.056
musculoskeletal system diseaseDOID:1700.046
disease of metabolismDOID:001466700.045
cardiovascular system diseaseDOID:128700.017
myopathyDOID:42300.016
muscle tissue diseaseDOID:6600.016
muscular diseaseDOID:008000000.016
cancerDOID:16200.016
disease of cellular proliferationDOID:1456600.016
organ system cancerDOID:005068600.016
cardiomyopathyDOID:005070000.015
heart diseaseDOID:11400.015
acquired metabolic diseaseDOID:006015800.011
diabetes mellitusDOID:935100.011
type 2 diabetes mellitusDOID:935200.011
glucose metabolism diseaseDOID:419400.011
carbohydrate metabolism diseaseDOID:005001300.011
intrinsic cardiomyopathyDOID:006003600.010
inherited metabolic disorderDOID:65500.010