Danio rerio

55 known processes

pycard

PYD and CARD domain containing

(Aliases: ASC,zgc:109874,asc1,zAsc,MGC109874)

pycard biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of innate immune responseGO:004508980.887
Human Mouse
defense response to bacteriumGO:0042742220.835
Human
protein secretionGO:000930610.810
Human Mouse
response to other organismGO:0051707970.806
Human Mouse
immune system processGO:00023762410.778
Human Mouse
regulation of biological qualityGO:00650082630.737
Mouse
response to molecule of bacterial originGO:0002237140.591
Human
positive regulation of defense response to virus by hostGO:000223000.591
Mouse
positive regulation of transportGO:005105020.583
Human Mouse
immune responseGO:0006955280.540
Human Mouse
response to stressGO:00069502630.487
Human Mouse
response to external biotic stimulusGO:0043207970.456
Human Mouse
response to drugGO:004249330.422
positive regulation of cellular processGO:00485222010.419
positive regulation of erk1 and erk2 cascadeGO:007037420.401
Human Mouse
regulation of cell communicationGO:00106462320.392
Human Mouse
regulation of primary metabolic processGO:00800903110.385
response to bacteriumGO:0009617580.371
Human Mouse
positive regulation of biological processGO:00485182530.366
positive regulation of programmed cell deathGO:0043068290.361
detection of chemical stimulus involved in sensory perceptionGO:005090730.312
regulation of defense response to virus by hostGO:005069110.311
Mouse
response to biotic stimulusGO:0009607970.307
Human Mouse
organelle organizationGO:00069962270.304
Human Mouse
positive regulation of secretion by cellGO:190353210.302
Human Mouse
antimicrobial humoral responseGO:001973020.289
cellular response to organic substanceGO:00713101050.281
Human
cellular response to chemical stimulusGO:00708871570.268
Human
regulation of i kappab kinase nf kappab signalingGO:004312240.242
Human
production of molecular mediator of immune responseGO:000244020.241
defense response to other organismGO:0098542330.238
Human Mouse
cognitionGO:005089010.238
leukocyte homeostasisGO:000177620.237
signal transductionGO:00071654550.232
Human Mouse
positive regulation of cellular component biogenesisGO:004408930.224
Mouse
response to lipidGO:0033993600.223
Human
response to external stimulusGO:00096052640.222
Human Mouse
response to chemicalGO:00422213200.217
Human
regulation of innate immune responseGO:0045088110.196
Human Mouse
protein metabolic processGO:00195381830.195
cell cycle processGO:0022402530.193
cellular response to molecule of bacterial originGO:007121930.167
Human
larval developmentGO:000216420.163
muscle structure developmentGO:00610611960.160
phagocytosisGO:000690930.157
Mouse
cellular response to external stimulusGO:007149620.156
specification of symmetryGO:00097992040.150
positive regulation of cell communicationGO:0010647560.148
Human Mouse
cellular protein metabolic processGO:00442671290.142
locomotionGO:00400113130.129
Mouse
gene expressionGO:00104672520.128
Human Mouse
agingGO:000756820.123
establishment of localizationGO:00512342440.121
Human Mouse
positive regulation of multicellular organismal processGO:0051240520.120
Human Mouse
regulation of signalingGO:00230512350.120
Human Mouse
defense response to virusGO:0051607100.118
Human Mouse
heterocycle metabolic processGO:00464832900.116
Human Mouse
cell cycleGO:0007049930.116
positive regulation of cytoskeleton organizationGO:005149530.113
Mouse
positive regulation of cytokine productionGO:000181920.113
Human Mouse
phagocytosis engulfmentGO:000691110.113
regulation of multicellular organismal processGO:00512392770.113
Human Mouse
positive regulation of lipid metabolic processGO:004583410.112
cellular macromolecule metabolic processGO:00442603910.110
positive regulation of cellular metabolic processGO:0031325940.107
organic cyclic compound metabolic processGO:19013603010.107
Human Mouse
regulation of erk1 and erk2 cascadeGO:007037240.106
Human Mouse
striated muscle cell differentiationGO:00511461290.105
i kappab kinase nf kappab signalingGO:000724940.101
Human
peptide metabolic processGO:000651810.101
cell morphogenesis involved in differentiationGO:00009041950.098
positive regulation of cell cycleGO:004578730.098
amine metabolic processGO:000930820.097
stem cell fate commitmentGO:004886510.097
negative regulation of cytokine productionGO:000181810.095
Human
regulation of establishment of protein localizationGO:007020140.095
Human Mouse
positive regulation of apoptotic processGO:0043065290.095
positive regulation of immune effector processGO:000269930.092
innate immune responseGO:0045087130.092
Human Mouse
brain developmentGO:00074202930.090
regulation of protein metabolic processGO:0051246560.089
regulation of cellular metabolic processGO:00313233200.089
cytokinesisGO:000091030.086
negative regulation of protein phosphorylationGO:000193340.085
Human
activation of immune responseGO:000225390.085
Human Mouse
central nervous system developmentGO:00074173870.084
organonitrogen compound metabolic processGO:1901564740.084
Mouse
myeloid cell homeostasisGO:0002262560.082
small gtpase mediated signal transductionGO:000726480.082
peptide transportGO:001583310.081
positive regulation of molecular functionGO:0044093330.081
cellular ketone metabolic processGO:0042180110.080
gastrulationGO:00073692080.078
negative regulation of sequence specific dna binding transcription factor activityGO:004343320.077
Human
rho protein signal transductionGO:000726650.077
organic substance transportGO:0071702580.076
Human Mouse
positive regulation of secretionGO:005104710.074
Human Mouse
regulation of production of molecular mediator of immune responseGO:000270010.073
blood vessel developmentGO:00015682460.073
cell morphogenesisGO:00009022890.072
biosynthetic processGO:00090582940.068
Human
humoral immune responseGO:000695950.067
positive regulation of signal transductionGO:0009967560.067
Human Mouse
regulation of epithelial cell proliferationGO:005067830.065
fatty acid transportGO:001590810.065
cellular response to lipopolysaccharideGO:007122230.063
Human
single organism transportGO:00447652060.063
Human Mouse
digestive tract developmentGO:00485652650.061
transportGO:00068102200.059
Human Mouse
regulation of immune system processGO:0002682340.057
Human Mouse
apoptotic processGO:00069151160.057
negative regulation of response to stimulusGO:00485851040.056
Human
positive regulation of catalytic activityGO:0043085250.056
cell surface receptor signaling pathwayGO:00071663250.053
Human
long chain fatty acid transportGO:001590910.052
regulation of defense responseGO:0031347140.052
Human Mouse
single organism localizationGO:19025782250.052
Human Mouse
heart contractionGO:0060047710.052
positive regulation of metabolic processGO:00098931080.052
response to abiotic stimulusGO:00096281220.051
response to organic cyclic compoundGO:0014070510.051
lipid digestionGO:004424130.051
regulation of peptidyl tyrosine phosphorylationGO:005073010.051
regulation of metabolic processGO:00192223590.050
regulation of response to biotic stimulusGO:000283120.050
Mouse
cytoskeleton dependent cytokinesisGO:006164030.049
regulation of intracellular signal transductionGO:1902531570.048
Human Mouse
regulation of developmental processGO:00507932470.048
ras protein signal transductionGO:000726570.048
maintenance of locationGO:005123540.047
cellular modified amino acid metabolic processGO:000657530.047
deathGO:00162651210.046
regulation of response to stimulusGO:00485832690.045
Human Mouse
positive regulation of lymphocyte mediated immunityGO:000270810.045
oligopeptide transportGO:000685710.044
regulation of signal transductionGO:00099662250.043
Human Mouse
tissue remodelingGO:004877140.043
homeostatic processGO:00425921420.043
intracellular signal transductionGO:0035556850.043
Human Mouse
antibacterial humoral responseGO:001973120.043
regulation of cellular amine metabolic processGO:003323800.042
multicellular organism growthGO:003526440.042
cell migrationGO:00164772370.042
Mouse
system processGO:00030081850.041
vasculature developmentGO:00019442780.041
determination of bilateral symmetryGO:00098552040.041
macromolecule modificationGO:00434121110.040
Human
stem cell maintenanceGO:001982740.040
cellular protein modification processGO:00064641000.040
Human
cellular component morphogenesisGO:00329893360.040
cellular response to endogenous stimulusGO:0071495680.039
regulation of gene expressionGO:00104682650.039
Human Mouse
protein modification processGO:00362111000.039
Human
regulation of mapk cascadeGO:0043408140.038
Human Mouse
regulation of cellular component organizationGO:0051128860.038
Human Mouse
regulation of catalytic activityGO:0050790550.038
epithelial cell differentiationGO:00308551160.037
regulation of immune effector processGO:000269750.037
Mouse
digestive system developmentGO:00551232890.036
single organism metabolic processGO:00447102170.036
Human Mouse
cellular amine metabolic processGO:004410620.036
response to virusGO:0009615210.036
Human Mouse
neuron developmentGO:00486662620.035
positive regulation of cellular amine metabolic processGO:003324000.035
response to transition metal nanoparticleGO:1990267280.035
oxoacid metabolic processGO:0043436310.035
guanosine containing compound catabolic processGO:190106920.035
Mouse
homeostasis of number of cellsGO:0048872620.034
regulation of cell cycleGO:0051726520.034
regulation of protein ubiquitinationGO:003139630.034
membrane invaginationGO:001032410.034
regulation of cell activationGO:005086510.034
Human Mouse
regulation of molecular functionGO:0065009700.034
response to woundingGO:00096111160.034
Mouse
skin developmentGO:0043588540.034
regulation of cellular ketone metabolic processGO:001056570.033
tube morphogenesisGO:00352393490.033
leukocyte differentiationGO:0002521250.033
regulation of protein transportGO:005122330.032
Human Mouse
positive regulation of notch signaling pathwayGO:004574730.032
regulation of cellular amino acid metabolic processGO:000652100.032
regulation of macromolecule metabolic processGO:00602553170.032
cellular response to xenobiotic stimulusGO:0071466350.031
defense response to gram negative bacteriumGO:005082980.031
Human
dna metabolic processGO:0006259270.031
positive regulation of protein complex assemblyGO:003133420.031
Mouse
response to oxygen containing compoundGO:1901700550.030
Human
establishment of localization in cellGO:0051649770.030
Human Mouse
response to fungusGO:0009620250.030
cellular nitrogen compound biosynthetic processGO:00442712180.030
Human
actin filament based processGO:0030029640.029
Mouse
cell projection morphogenesisGO:00488582440.029
nuclear divisionGO:0000280230.029
positive regulation of cell deathGO:0010942290.029
regulation of actin filament based processGO:003297090.029
Mouse
regulation of multicellular organismal developmentGO:20000262230.029
regulation of wound healingGO:006104120.028
stem cell proliferationGO:007208940.028
positive regulation of cellular biosynthetic processGO:0031328680.028
regulation of multicellular organism growthGO:004001440.028
cellular amide metabolic processGO:004360340.028
positive regulation of nitrogen compound metabolic processGO:0051173690.028
response to corticosteroidGO:003196010.028
zymogen activationGO:003163830.027
Mouse
multicellular organismal water homeostasisGO:005089110.027
gland developmentGO:00487321430.027
cell motilityGO:00488702440.027
Mouse
response to nutrientGO:000758430.026
regulation of apoptotic processGO:0042981980.026
embryo development ending in birth or egg hatchingGO:00097922710.026
heart processGO:0003015710.026
cellular component movementGO:00069283350.026
Mouse
regulation of cellular protein metabolic processGO:0032268520.026
regulation of nucleobase containing compound metabolic processGO:00192192500.026
Human Mouse
regulation of cell deathGO:00109411030.026
regulation of cytokine productionGO:000181730.026
Human Mouse
single organism organelle organizationGO:19025891990.026
Mouse
spermatid developmentGO:000728620.026
regulation of programmed cell deathGO:00430671010.026
plasma membrane repairGO:000177820.025
positive regulation of catabolic processGO:000989640.025
nitrogen compound metabolic processGO:00068073190.025
Human Mouse
programmed cell deathGO:00125011190.025
response to hypoxiaGO:0001666250.025
positive regulation of immune responseGO:0050778110.025
Human Mouse
organic acid metabolic processGO:0006082310.025
regulation of cellular macromolecule biosynthetic processGO:20001122220.024
Human
regulation of cell proliferationGO:0042127370.024
Mouse
regulation of phosphorus metabolic processGO:0051174430.024
Human Mouse
erk1 and erk2 cascadeGO:007037140.024
Human Mouse
response to lipopolysaccharideGO:0032496130.024
Human
cell type specific apoptotic processGO:0097285220.023
regulation of vesicle mediated transportGO:006062790.023
Mouse
angiogenesisGO:00015251580.023
cellular component biogenesisGO:00440851780.023
Mouse
cellular component disassemblyGO:002241110.023
regulation of nucleic acid templated transcriptionGO:19035062130.023
Human
autophagyGO:000691440.023
Mouse
regulation of striated muscle contractionGO:000694220.023
adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domainsGO:000246040.022
organic anion transportGO:0015711150.022
heart morphogenesisGO:00030071560.022
regulation of cyclin dependent protein serine threonine kinase activityGO:000007910.022
negative regulation of blood vessel endothelial cell migrationGO:004353710.022
negative regulation of endothelial cell migrationGO:001059610.022
regulation of biosynthetic processGO:00098892500.022
Human
muscle fiber developmentGO:0048747520.021
cellular localizationGO:0051641970.021
Human Mouse
response to inorganic substanceGO:0010035380.021
cell activationGO:0001775160.021
Human Mouse
protein targeting to nucleusGO:004474430.021
cellular amino acid metabolic processGO:000652070.021
positive regulation of myeloid cell differentiationGO:004563920.021
cytoplasmic pattern recognition receptor signaling pathwayGO:000275310.021
vesicle mediated transportGO:0016192220.021
Mouse
cellular process involved in reproduction in multicellular organismGO:0022412280.021
positive regulation of response to stimulusGO:0048584800.021
Human Mouse
gtp metabolic processGO:004603940.020
Mouse
positive regulation of cell adhesionGO:004578510.020
response to xenobiotic stimulusGO:0009410450.020
guanosine containing compound metabolic processGO:190106840.020
Mouse
positive regulation of hydrolase activityGO:0051345130.020
phosphorylationGO:0016310690.020
Human Mouse
protein localization to plasma membraneGO:007265910.020
positive regulation of immune system processGO:0002684170.020
Human Mouse
cranial nerve developmentGO:0021545420.020
reproductionGO:0000003400.019
regulation of localizationGO:00328791040.019
Human Mouse
multicellular organism reproductionGO:0032504350.019
response to alkaloidGO:004327920.019
determination of left right symmetryGO:00073681790.019
eye developmentGO:00016542770.019
gamete generationGO:0007276330.019
protein importGO:001703830.019
regulation of cellular biosynthetic processGO:00313262450.019
Human
response to endogenous stimulusGO:0009719830.019
positive regulation of cellular amino acid metabolic processGO:004576400.019
regulation of rho protein signal transductionGO:003502320.018
Mouse
regulation of nucleoside metabolic processGO:000911820.018
Mouse
macromolecule localizationGO:0033036540.018
Human Mouse
negative regulation of multicellular organismal processGO:0051241690.018
Human
response to mechanical stimulusGO:0009612240.018
cellular response to stressGO:0033554620.018
Human
cellular response to starvationGO:000926710.018
regulation of cell differentiationGO:00455951420.018
leukocyte activationGO:0045321120.018
Human Mouse
multi organism processGO:00517041340.017
Human Mouse
positive regulation of protein polymerizationGO:003227320.017
Mouse
developmental growthGO:00485891660.017
negative regulation of signal transductionGO:0009968940.017
Human
wound healingGO:0042060900.017
peripheral nervous system developmentGO:0007422550.017
positive regulation of signalingGO:0023056560.017
Human Mouse
immune effector processGO:0002252230.017
Human Mouse
protein localization to membraneGO:007265790.017
negative regulation of defense responseGO:003134820.017
neutrophil homeostasisGO:000178010.017
establishment of protein localizationGO:0045184140.017
Human Mouse
peripheral nervous system neuron developmentGO:0048935220.017
response to glucocorticoidGO:005138410.017
neuroblast fate commitmentGO:001401710.017
phosphorus metabolic processGO:00067931090.017
Human Mouse
cellular macromolecule biosynthetic processGO:00346452240.017
Human
positive regulation of extrinsic apoptotic signaling pathwayGO:200123810.017
Human
transcription dna templatedGO:00063511810.017
Human
regulation of protein complex disassemblyGO:004324410.017
negative regulation of cell deathGO:0060548600.016
positive regulation of glial cell differentiationGO:004568710.016
mapk cascadeGO:0000165180.016
Human Mouse
regulation of bindingGO:005109830.016
negative regulation of cellular processGO:00485232830.016
Human
folic acid containing compound metabolic processGO:000676020.016
positive regulation of dna metabolic processGO:005105410.016
keratinocyte differentiationGO:003021600.016
digestive tract morphogenesisGO:00485462310.016
positive regulation of production of molecular mediator of immune responseGO:000270210.016
cellular component assemblyGO:00226071700.016
Mouse
phosphate containing compound metabolic processGO:00067961080.016
Human Mouse
lymphocyte proliferationGO:004665110.015
Mouse
sensory perception of chemical stimulusGO:000760630.015
neuroblast differentiationGO:001401610.015
carboxylic acid metabolic processGO:0019752220.015
myotube differentiationGO:0014902450.015
regulation of protein localization to nucleusGO:190018020.015
positive regulation of jnk cascadeGO:004633030.015
Human
morphogenesis of an epitheliumGO:00020093330.015
regulation of circadian sleep wake cycle sleepGO:004518710.015
cellular aromatic compound metabolic processGO:00067252950.015
Human Mouse
multicellular organismal reproductive processGO:0048609350.015
nuclear importGO:005117030.015
macromolecule biosynthetic processGO:00090592270.015
Human
negative regulation of kinase activityGO:003367340.014
Human
positive regulation of cell activationGO:005086710.014
Human Mouse
glycoprotein biosynthetic processGO:0009101210.014
reactive oxygen species metabolic processGO:007259360.014
chemical homeostasisGO:0048878490.014
negative regulation of programmed cell deathGO:0043069580.014
regulation of oligodendrocyte differentiationGO:004871310.014
hemopoiesisGO:00300971830.014
protein localization to nucleusGO:003450430.014
meiotic nuclear divisionGO:000712640.014
head developmentGO:00603223030.014
endocardial cushion formationGO:000327220.014
regulation of phosphate metabolic processGO:0019220430.014
Human Mouse
response to cytokineGO:003409770.014
Human
positive regulation of intracellular signal transductionGO:1902533150.013
Human Mouse
small molecule metabolic processGO:0044281770.013
Mouse
nucleic acid metabolic processGO:00903042440.013
Human
negative regulation of signalingGO:0023057960.013
Human
positive regulation of epithelial cell proliferationGO:005067910.013
negative regulation of protein transportGO:005122430.013
negative regulation of biological processGO:00485193040.013
Human
behaviorGO:0007610740.013
anion transportGO:0006820380.013
regulation of heart contractionGO:0008016320.013
pole plasm assemblyGO:000731540.013
response to organic substanceGO:00100331530.013
Human
regulation of protein complex assemblyGO:004325430.013
Mouse
localization of cellGO:00516742440.013
Mouse
neuron projection morphogenesisGO:00488121610.013
phosphatidylinositol mediated signalingGO:004801520.012
regulation of phGO:000688530.012
growthGO:00400071740.012
b cell activationGO:004211320.012
positive regulation of gtp catabolic processGO:003312610.012
cellular response to organic cyclic compoundGO:0071407380.012
nucleobase containing compound metabolic processGO:00061392740.012
Human Mouse
response to uvGO:000941130.012
membrane organizationGO:0061024210.012
regulation of cellular phGO:003064110.012
regulation of immune responseGO:0050776140.012
Human Mouse
one carbon compound transportGO:0019755140.011
positive regulation of biosynthetic processGO:0009891680.011
single organism cellular localizationGO:1902580460.011
protein import into nucleusGO:000660630.011
regulation of protein modification by small protein conjugation or removalGO:190332030.011
response to alcoholGO:0097305140.011
positive regulation of stem cell proliferationGO:200064810.011
regulation of dna replicationGO:000627530.011
cellular response to hormone stimulusGO:0032870390.011
spermatid differentiationGO:004851520.011
regulation of coagulationGO:005081820.011
positive regulation of nucleobase containing compound metabolic processGO:0045935690.011
mitotic cell cycleGO:0000278640.011
negative regulation of apoptotic processGO:0043066550.011
adherens junction organizationGO:003433240.011
epidermal cell differentiationGO:0009913360.011
g1 s transition of mitotic cell cycleGO:000008210.011
positive regulation of gtpase activityGO:004354710.011
nucleobase containing small molecule metabolic processGO:0055086320.011
Mouse
regulation of protein targetingGO:190353320.011
ion transportGO:00068111140.011
rna biosynthetic processGO:00327741810.011
Human
regulation of gtpase activityGO:004308720.011
Mouse
epithelial tube morphogenesisGO:00605621480.011
protein localizationGO:0008104400.011
Human Mouse
regulation of cell cycle processGO:0010564200.011
cellular response to extracellular stimulusGO:003166820.011
protein polymerizationGO:005125840.011
Mouse
organonitrogen compound biosynthetic processGO:1901566470.011
macromolecular complex subunit organizationGO:0043933740.011
Mouse
pteridine containing compound metabolic processGO:004255830.011
protein depolymerizationGO:005126110.011
regulation of transportGO:0051049450.010
Human Mouse
regulation of dna templated transcription in response to stressGO:004362000.010
mononuclear cell proliferationGO:003294310.010
Mouse
gtp catabolic processGO:000618420.010
Mouse
immune system developmentGO:00025201910.010
atrioventricular valve developmentGO:0003171110.010
organelle fusionGO:004828430.010
positive regulation of cellular component organizationGO:0051130130.010
Human Mouse
cell projection organizationGO:00300302840.010
negative regulation of epithelial cell migrationGO:001063310.010
regulation of leukocyte mediated immunityGO:000270310.010
neurological system processGO:0050877620.010
blood circulationGO:0008015870.010
regulation of muscle hypertrophyGO:001474320.010
muscle cell differentiationGO:00426921390.010
cellular response to oxygen levelsGO:007145310.010
regulation of transferase activityGO:0051338160.010
Human

pycard disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in zebrafish and predicted with the zebrafish functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.025
disease of metabolismDOID:001466700.017
musculoskeletal system diseaseDOID:1700.013
amyloidosisDOID:912000.012
acquired metabolic diseaseDOID:006015800.012
integumentary system diseaseDOID:1600.010